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JAMA The Journal of the American Medical Association
Journal Prestige (SJR): 8.876
Citation Impact (citeScore): 7
Number of Followers: 1800  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 0098-7484 - ISSN (Online) 1538-3598
Published by American Medical Association Homepage  [14 journals]
  • Highlights for September 18, 2018
    • Pages: 1083 - 1085
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2017.12548
      Issue No: Vol. 320, No. 11 (2018)
       
  • JAMA
    • Pages: 1087 - 1088
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2017.12549
      Issue No: Vol. 320, No. 11 (2018)
       
  • A Day in the Life: Caring for Transgender Patients in New York City
    • Authors: Abbasi J.
      Pages: 1092 - 1093
      Abstract: This Medical News article profiles Joshua D. Safer, MD, who leads Mount Sinai’s Center for Transgender Medicine and Surgery.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11218
      Issue No: Vol. 320, No. 11 (2018)
       
  • Are Bacteria Transplants the Future of Eczema Therapy'
    • Authors: Abbasi J.
      Pages: 1094 - 1095
      Abstract: This Medical News article discusses early clinical trials of beneficial bacteria therapy for eczema, or atopic dermatitis.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12334
      Issue No: Vol. 320, No. 11 (2018)
       
  • Enabling School Success to Improve Community Health
    • Authors: Sharfstein J; Santamaria R.
      Pages: 1096 - 1096
      Abstract: From an innovative play space designed to teach children about concepts of engineering and mathematics to an outdoor teaching kitchen to help students learn about nutrition and to new school health services for vulnerable teens, several recenthttp://nantuckethospital.org/nch-awards-762000-to-local-nonprofits-to-address-the-islands-most-pressing-health-issues/community investments by the local hospital in Nantucket, Massachusetts, aim to help the island’s children stay and succeed in school. And for good reason: there may be no better long-term investment in health.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12567
      Issue No: Vol. 320, No. 11 (2018)
       
  • Armadillos Bring Risk of Leprosy
    • Authors: Friedrich MJ.
      Pages: 1097 - 1097
      Abstract: Armadillos can serve as an environmental reservoir for Mycobacterium leprae, the bacterial agent that causes leprosy, and hunting, handling, or eating armadillo meat can increase the risk of infection, report an international team of researchers in PLoS Neglected Tropical Diseases.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12741
      Issue No: Vol. 320, No. 11 (2018)
       
  • Cardiovascular Disease in India
    • Authors: Friedrich MJ.
      Pages: 1097 - 1097
      Abstract: Ischemic heart disease deaths are rising in India, particularly in rural areas and among young adults, while deaths from stroke have dropped in most parts of the country, according to a study in The Lancet Global Health.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13373
      Issue No: Vol. 320, No. 11 (2018)
       
  • Early Initiation of Breastfeeding
    • Authors: Friedrich MJ.
      Pages: 1097 - 1097
      Abstract: Globally, only 2 out of 5 newborns began breastfeeding within an hour of birth in 2017, leaving an estimated 78 million newborns to wait over 1 hour to be put to the breast, according to a new report from the United Nations Children’s Fund (UNICEF) and the World Health Organization (WHO).
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13372
      Issue No: Vol. 320, No. 11 (2018)
       
  • Brain Stimulation Approved for Obsessive-Compulsive Disorder
    • Authors: Voelker R.
      Pages: 1098 - 1098
      Abstract: The FDA has expanded the approved indications for transcranial magnetic stimulation (TMS) to include obsessive-compulsive disorder (OCD). In 2008, TMS was approved to treat major depression and in 2013 got the nod for pain from certain migraine headaches.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13301
      Issue No: Vol. 320, No. 11 (2018)
       
  • Generic Form of EpiPen Approved
    • Authors: Voelker R.
      Pages: 1098 - 1098
      Abstract: Aiming to spur competition, lower prices, and ward off drug shortages, the FDA approved the first generic epinephrine autoinjector to treat life-threatening allergic reactions. The approval came 2 years after public outcries concerning steep price hikes for the brand name product, EpiPen, manufactured by the global drug maker Mylan N.V.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13297
      Issue No: Vol. 320, No. 11 (2018)
       
  • Vaginal Ring Contraceptive Remains Effective for 1 Year
    • Authors: Voelker R.
      Pages: 1098 - 1098
      Abstract: The first vaginal ring contraceptive that women can use for a full year has received FDA approval. In comparison, a contraceptive ring currently marketed in the United States has to be replaced monthly.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13299
      Issue No: Vol. 320, No. 11 (2018)
       
  • Prospects for a Deep Learning Health Care System
    • Authors: Naylor C.
      Pages: 1099 - 1100
      Abstract: In this Viewpoint, David Naylor reviews factors driving the adoption of deep learning and artificial intelligence in health care, including the digitization of health data and efficiencies in processing those data sets to automate routine clinical tasks and accelerate research and technology development.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11103
      Issue No: Vol. 320, No. 11 (2018)
       
  • The Potential of Deep Learning Technology to Transform Health Care
    • Authors: Hinton G.
      Pages: 1101 - 1102
      Abstract: In this Viewpoint, Geoffrey Hinton of Google’s Brain Team discusses the basics of neural networks: their underlying data structures, how they can be trained and combined to process complex health data sets, and future prospects for harnessing their unsupervised learning to clinical challenges.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11100
      Issue No: Vol. 320, No. 11 (2018)
       
  • Informatics, Data Science, and Artificial Intelligence
    • Authors: Zhu L; Zheng W.
      Pages: 1103 - 1104
      Abstract: This Viewpoint discusses how advances in data science and informatics are driving a transformation of biomedical research and clinical practice toward models where data mining and artificial intelligence will underlie development of precision therapies.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.8211
      Issue No: Vol. 320, No. 11 (2018)
       
  • Moments of Silence in the Intensive Care Unit
    • Authors: Barbash IJ.
      Pages: 1105 - 1106
      Abstract: In this narrative medicine essay, an intensivist tells how he and his colleagues joined in a moment of silence to honor the ICU death of a man under their care with a do-not-resuscitate order.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12753
      Issue No: Vol. 320, No. 11 (2018)
       
  • Clinical Implications and Challenges of Artificial Intelligence and Deep
           Learning
    • Authors: Stead WW.
      Pages: 1107 - 1108
      Abstract: Artificial intelligence (AI) and deep learning are entering the mainstream of clinical medicine. For example, in December 2016, Gulshan et al reported development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. An accompanying editorial by Wong and Bressler pointed out limits of the study, the need for further validation of the algorithm in different populations, and unresolved challenges (eg, incorporating the algorithm into clinical work flows and convincing clinicians and patients to “trust a ‘black box’”). Sixteen months later, the Food and Drug Administration (FDA) permitted marketing of the first medical device to use AI to detect diabetic retinopathy. FDA reduced the risk of releasing the device by limiting the indication for use to screening adults who do not have visual symptoms for greater than mild retinopathy, to refer them to an eye care specialist.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11029
      Issue No: Vol. 320, No. 11 (2018)
       
  • Symptoms of Burnout Among Physicians
    • Authors: Schwenk TL; Gold KJ.
      Pages: 1109 - 1110
      Abstract: A patient complains of intermittent wheezing. He cannot characterize the wheezing further with regard to timing, precipitating events, or how it affects his health. A physician makes a diagnosis of asthma without further evaluation, gives the patient several recommendations regarding lifestyle modification and potential precipitants, and prescribes an inhaled long-acting β-agonist and corticosteroid.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11703
      Issue No: Vol. 320, No. 11 (2018)
       
  • Weight Management in Adults With Obesity
    • Authors: Yanovski SZ.
      Pages: 1111 - 1113
      Abstract: In this issue of JAMA, the US Preventive Services Task Force (USPSTF) presents its 2018 recommendation statement and an accompanying evidence review on weight loss interventions to prevent obesity-related morbidity and mortality in adults. In this update of the 2012 USPSTF recommendation, the major recommendation did not substantially change: clinicians should offer or refer adults with a body mass index (BMI) of 30 or higher to intensive, multicomponent behavioral interventions. The task force concluded that there is moderate certainty of moderate net benefit, with little risk of harm, and provided an evidence grade of “B,” indicating that provision of the service is recommended. Payers often use such recommendations to inform coverage decisions.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.11031
      Issue No: Vol. 320, No. 11 (2018)
       
  • Association of Clinical Specialty With Symptoms of Burnout and Regret
           Among US Resident Physicians
    • Authors: Dyrbye LN; Burke SE, Hardeman RR, et al.
      Pages: 1114 - 1130
      Abstract: This survey study investigates risk factors for symptoms of burnout and career choice regret among US physicians during their second year of residency.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12615
      Issue No: Vol. 320, No. 11 (2018)
       
  • Prevalence of Burnout Among Physicians
    • Authors: Rotenstein LS; Torre M, Ramos MA, et al.
      Pages: 1131 - 1150
      Abstract: This systematic review assesses how burnout among practicing physicians has been defined in the published medical literature and estimates its prevalence by definitions, assessment methods, and study quality.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12777
      Issue No: Vol. 320, No. 11 (2018)
       
  • Accuracy of [ 18 F]flortaucipir PET for Alzheimer Disease vs Other
           Neurodegenerative Disorders
    • Authors: Ossenkoppele R; Rabinovici GD, Smith R, et al.
      Pages: 1151 - 1162
      Abstract: This diagnostic accuracy study characterizes the ability of [18F]flortaucipir to discriminate Alzheimer from non-Alzheimer neurodegenerative disorders among patients at dementia clinics and research centers.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.12917
      Issue No: Vol. 320, No. 11 (2018)
       
  • USPSTF Recommendation: Behavioral Interventions to Prevent Adult
           Obesity-Related Outcomes
    • Pages: 1163 - 1171
      Abstract: This 2018 Recommendation Statement from the US Preventive Services Task Force recommends that clinicians offer or refer adults with a body mass index of 30 or higher to intensive, multicomponent behavioral interventions (B recommendation).
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13022
      Issue No: Vol. 320, No. 11 (2018)
       
  • USPSTF Evidence Report: Behavioral Interventions to Prevent Adult
           Obesity-Related Outcomes
    • Authors: LeBlanc ES; Patnode CD, Webber EM, et al.
      Pages: 1172 - 1191
      Abstract: This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on interventions to prevent obesity-related morbidity and mortality summarizes published evidence on the benefits and harms of behavioral and pharmacotherapy weight loss and weight loss maintenance interventions in adults.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.7777
      Issue No: Vol. 320, No. 11 (2018)
       
  • On Deep Learning for Medical Image Analysis
    • Authors: Carin L; Pencina MJ.
      Pages: 1192 - 1193
      Abstract: This JAMA Guide to Statistics and Methods explains the basic concepts underlying convolutional neural networks (CNNs), a type of machine learning being used to automate the reading of medical images.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13316
      Issue No: Vol. 320, No. 11 (2018)
       
  • Association Between Maintaining Certification in General Surgery and
           Loss-of-License Actions
    • Authors: Jones AT; Kopp JP, Malangoni MA.
      Pages: 1195 - 1196
      Abstract: This study uses American Board of Surgery data to assess the association between maintainence of certification in general surgery and loss-of-license actions after expiration of the initial 10-year certification among general surgeons.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.9550
      Issue No: Vol. 320, No. 11 (2018)
       
  • Scholarship Support for Veterans Enrolling in MD, JD, and MBA Programs
    • Authors: Graves S; Seagle BL, Kocherginsky M, et al.
      Pages: 1197 - 1198
      Abstract: This study compares Veterans Administration (VA) scholarship support for veterans enrolling in degree-granting medical schools vs law or business programs at the same institutions.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.10260
      Issue No: Vol. 320, No. 11 (2018)
       
  • Premedication for Neonates and Nonemergency Intubation
    • Authors: Fideler F; Grasshoff C.
      Pages: 1199 - 1199
      Abstract: To the Editor Dr Durrmeyer and colleagues investigated 173 neonates requiring nonemergent intubation in a multicenter, double-blind clinical trial, randomly assigning infants to receive atropine-propofol or atropine-atracurium-sufentanil before nasotracheal intubation. The authors reported that “the frequency of prolonged desaturation did not differ significantly [between groups]…. However, the study may have been underpowered to detect a clinically important difference.”
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.10014
      Issue No: Vol. 320, No. 11 (2018)
       
  • Premedication for Neonates and Nonemergency Intubation—Reply
    • Authors: Durrmeyer X; Tourneux P, Dechartres A.
      Pages: 1199 - 1200
      Abstract: In Reply Drs Fideler and Grasshoff raise 2 concerns regarding our trial comparing 2 premedication regimens for neonates requiring nonemergency intubation in the neonatal intensive care unit (NICU). Concerning the potential neurotoxicity of anesthetics and analgesics on the developing human brain, epidemiological data on surgical anesthesia and experimental animal data have suggested an association between surgical anesthesia and neurodevelopmental impairment, resulting in an FDA warning in 2016. However, a single, brief exposure to a general anesthetic, as used in our study, was not within the scope of the FDA warning. Available data from premature infants exposed to anesthetics, sedatives, or analgesics in the NICU are limited but reassuring thus far. Epidemiological studies that found an association with neurodevelopmental impairment could not disentangle the respective roles of anesthetics, surgery, pain, or the underlying condition. Repeated early painful experiences in the NICU are associated with impaired neurodevelopment when premature infants are older, so it is necessary to evaluate the balance between eventual toxicity and pain. For this purpose, neurodevelopmental follow-up of the infants in the study is ongoing.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.10025
      Issue No: Vol. 320, No. 11 (2018)
       
  • Safety of Topical Calcineurin Inhibitors for Hailey-Hailey Disease
    • Authors: Han F.
      Pages: 1200 - 1200
      Abstract: To the Editor Dr Haley and colleagues described a patient with Hailey-Hailey disease (HHD) in a JAMA Clinical Challenge article. The authors stated that long-term topical calcineurin inhibitors (TCIs) such as tacrolimus or pimecrolimus could be applied to control HHD because they lacked the adverse effects of topical corticosteroids. However, the US Food and Drug Administration (FDA) issued a public health advisory in 2005 about a potential cancer risk associated with the use of tacrolimus, based on animal studies and case reports in a small number of patients. Although the finding is controversial, the number of patients in whom cancer developed after TCI therapy has been increasing. Development of squamous cell carcinoma has been reported with topical application of 0.1% tacrolimus for 10 months in a patient with HHD, and tacrolimus therapy may have promoted the development of squamous cell carcinoma from the HHD lesion. Because of limited and uncertain data on the long-term safety of topical TCIs in HHD treatment, especially as these agents are used off-label, TCIs should be applied as a second-line therapy for short-term or intermittent treatment of HHD, and patients treated with TCIs require careful follow-up.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.9554
      Issue No: Vol. 320, No. 11 (2018)
       
  • Safety of Topical Calcineurin Inhibitors for Hailey-Hailey
           Disease—Reply
    • Authors: Haley CT; Mui U, Tyring SK.
      Pages: 1200 - 1201
      Abstract: In Reply Mr Han raises an important point regarding the use of TCIs, which are labeled for use in atopic dermatitis, to treat HHD. The FDA issued a black box warning of a possible association between TCI use and the development of cancer (lymphoma and skin) based on case reports and animal studies, a warning not supported by the American Academy of Dermatology. Most of these animal studies demonstrated an increased risk of malignancy after administration of systemic or topical calcineurin inhibitors in doses far exceeding those used by humans.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.9558
      Issue No: Vol. 320, No. 11 (2018)
       
  • Treatment of Chronic Hepatitis B Infection
    • Authors: Zhou Y.
      Pages: 1201 - 1201
      Abstract: To the Editor Dr Tang and colleagues summarized the current clinical evidence on the management of chronic hepatitis B virus (HBV) infection. I have some concerns about the review. First, it is not adequate to designate HBV e antigen (HBeAg) as HBV envelope antigen. HBeAg is not a structural component of HBV itself, but a derivative of HBV core antigen (HBcAg) that is secreted into the circulation during viral replication. The HBV envelope does not contain HBeAg.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.10007
      Issue No: Vol. 320, No. 11 (2018)
       
  • Treatment of Chronic Hepatitis B Infection—Reply
    • Authors: Tang L; Kottilil S.
      Pages: 1202 - 1202
      Abstract: In Reply The e in HBeAg has been referred to as an abbreviation for “envelope” in several recent studies. Magnius and Espmark first described a new antigenic specificity in individuals positive for Australia antigen (now known as HBsAg) and proposed the designation of e for this new specificity. Although they did not state what the e stood for, others have reported that Magnius and Espmark meant for it to be a stand-alone e. Because the earliest publications do not refer to the e antigen as standing for envelope, we conclude that it does not. The review article has been corrected online and a correction notice appears in this issue.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.10021
      Issue No: Vol. 320, No. 11 (2018)
       
  • Incorrect Expansion of a Term and Other Clarifications
    • Pages: 1202 - 1202
      Abstract: In the Review entitled “Chronic Hepatitis B Infection: A Review” published in the May 1, 2018, issue of JAMA, the term “hepatitis B envelope antigen” should have been “hepatitis B e antigen” in several places throughout the article. In Figure 1, the hepatitis e antigen was removed from the depiction of the hepatitis B virion. In Table 3, in the “isolated core” row, wording in the last column “interpretation details” was revised for the third bullet point. This article was corrected online.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.9637
      Issue No: Vol. 320, No. 11 (2018)
       
  • Spring Downsizing
    • Authors: Pies R.
      Pages: 1203 - 1203
      Abstract: The lilac buds  are plumper now,unharmed  by April snows.A colony of ladybugs  feeds on honeyyou dabbed  on our antique window.Our last April here,  we inventorywhat we’ll keep,  what must go.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.5762
      Issue No: Vol. 320, No. 11 (2018)
       
  • Proprietaries, Pianos and Probity
    • Pages: 1204 - 1204
      Abstract: A correspondent, in calling attention to one of a series of resolutions we quoted last week, comments as follows: “Had this resolution been passed by the American Medical Association and been endorsed and published by The Journal, I am inclined to think that frenzied protests would have arisen in certain quarters about the attempt of the Association to throttle ‘independent medical journalism.’” The resolution referred to by our correspondent reads as follows:
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2017.12578
      Issue No: Vol. 320, No. 11 (2018)
       
  • Behavioral Interventions for Weight Loss
    • Authors: Jin J.
      Pages: 1210 - 1210
      Abstract: This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on behavioral interventions for weight loss to prevent obesity-related problems in adults.
      PubDate: Tue, 18 Sep 2018 00:00:00 GMT
      DOI: 10.1001/jama.2018.13125
      Issue No: Vol. 320, No. 11 (2018)
       
 
 
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