Similar Journals
HOME > Journal Current TOC
|
Journal of Medical Histology
Number of Followers: 8  Open Access journalISSN (Print) 2536-9172 - ISSN (Online) 2536-930X Published by Cairo Univeristy  [5 journals]
|
- The possible therapeutic effect of Stem Cells-Conditioned Medium on Statin
induced animal model ...
Abstract: Myopathies are diseases with a high incidence rate in the entire world because skeletal muscle degeneration gradually impairs patient movement and may even result in death, necessitating the urgent need for an effective cure. This study aims to explore the efficacy of stem cell conditioned medium (SC-CM) supplied by 2 distinct routes (IMIV) to repair injured skeletal muscle in a rat model of statin-induced myopathy..Fifty adult male albino rats were used in this study, and they were equally divided into five groups. the control group, IV conditioned medium treated group in which myopathy was induced then the rats were IV injected with 0.5 ml of SC-CM in tail vein, IM conditioned medium treated group the rats were locally injected with 0.5 ml of SC-CM after induction of myopathy, the untreated myopathy group was left without treatment for 4 weeks. Blood samples and muscular specimens from all groups were collected for biochemical (CK-MM and Myoglobin levels) and histological studies. All measurements were statistically analyzed.The myopathy group showed marked muscle degeneration, with inflammatory cells infiltration. Compared with control group, there was significant decrease in the area% of PAS and the number of myogenin positive cells and significant increase in mean CK-MM and MYO levels and in the area% of collagen and caspase3 positive cells. Four weeks after SC-CM injection (IMIV), there was marked improvement in histological architecture of the skeletal muscle and all measured parameters. The improvement was more obvious in the IV injected group.
PubDate: Sun, 14 May 2023 22:00:00 +010
- The efficacy of the adipose tissue derived mesenchymal stem cells in the
treatment of the lead ...
Abstract: Background and objectives: Lead acetate is one of the heavy metals that causes food, water and air pollution. Exposure to lead acetate causes toxic effects on several body organs including the kidney. The adipose tissue contains multipotent mesenchymal stem cells that could be isolated and cultured on suitable media to proliferate and give large number of stem cells. When injected into a living animal body, these stem cells have the ability to migrate to the sites of the lesions to replace the destroyed cells. The aim of the present study was to evaluate the possibility of the adipose tissue derived mesenchymal stem cells (Ad-MSCs) to ameliorate the nephrotoxic effects of lead acetate.Material and methods: Fifty adult male albino rats were used in this work. Ten rats were used as a source of the Ad-MSCs and the other forty rats were used in the experimental study. These forty rats were randomly divided into four groups; group 1 (control group), group 2 (lead acetate-treated group) received lead acetate to induce nephrotoxicity, group 3 (recovery group) received lead acetate to induce nephrotoxicity then left for spontaneous recovery. Group 4 (Ad-MSCs-treated group) received lead acetate to induce nephrotoxicity then, receive the Ad-MSCs to induce renal recovery.Results: Lead acetate administration caused impaired renal function, disturbed renal oxidant/antioxidant status and histological renal destruction with insignificant spontaneous recovery. Administration of Ad-MSCs alleviated the biochemical and histological nephrotoxic effects of lead acetate.Conclusion: The Ad-MSCs have curative properties against the nephrotoxic effects caused by lead acetate.
PubDate: Wed, 26 Apr 2023 22:00:00 +010
- Effect of Chronic Stress on Suprarenal Cortex and Possible Therapeutic
Potential of Ibuprofen ...
Abstract: Humans are constantly subjected to different stressors that endanger their ability to live a normal life. Since the adrenal gland is the primary organ implicated in the stress response, the purpose of this study was to assess the effects of stress on this organ and the contribution of ibuprofen and Mesenchymal stem cells microvesicles to ameliorate these effects. Material & methods: Four groups of ten rats each: control group, stress group that subjected to various forms of stress for two weeks Ibuprofen group received an intraperitoneal injection of 60 mg/kg ibuprofen after the stress period. MSC-MVs group received a single intravenous injection of 15 ul of MSC-MVs in 0.5 ml PBS after the stress. The rats then were sacrificed, and adrenal gland samples were prepared for immunohistochemical staining and light microscopy. Blood samples was taken for analysis of cortisol, aldosterone, malondialdehyde, and interleukin-6 levels. Result: Sections stained with H&E and immunohistochemical stains showed a mild improvement in ibuprofen group. The biochemical results confirmed that MSC-MVs group results were equivalent to those of the control group at the same period. There was no observable difference between the control group and MSC-MVs group. Conclusion: When given chronically and simultaneously under stressful settings to male albino rats, MSCs-MVs improves the histological alterations of the adrenal gland. Ibuprofen also helps these modifications, but to a lesser extent
PubDate: Wed, 15 Feb 2023 22:00:00 +010
- Effect of Topical application of Stem Cells - Conditioned Medium versus
their derived Exosomes ...
Abstract: Background: corneal ulcers are a serious vision frightening emergency. Even with accurate treatment, patients may suffer complications as perforation, scarring, cataracts, glaucoma, synechiae, and even loss of vision. Stem cells‐based treatment is considered as a promising approach in corneal ulcer treatment. Now a days, alternative stem cell conditioned medium (CM) and exosomes (EXs) -based treatment for corneal ulcers are feasible approaches.Aim: to compare the possible ameliorating effects of stem cells conditioned medium (CM) versus their derived exosomes (EXs) in corneal ulcer healing. Material and Method: 40 rats were randomly allocated into five groups; the control, corneal ulcer, CM-treated, EXs-treated and recovery groups; corneas were obtained for biochemical assessment of TNFα, VEGF, MDA and GSH levels and for histological structure . Corneal damage was assessed by histopathological scoring and immunohistochemical staining.Results: corneal ulcer group revealed a significant increase in TNFα, VEGF and MDA levels and also revealed significant decrease in the GSH level. Histological assessment revealed structural alteration indicating severs corneal damage. Moreover a significant increase in P53 expression. Interestingly, CM and EXs administration significantly decreased TNFα, VEGF and MDA levels and increased GSH level. Additionally, there was obvious improvement in histological structure of corneas, and significant decrease in P53 expression.Conclusion: To the best of our knowledge, this is the first study to investigate CM versus EXs in treatment of corneal ulcer. Both EXs and CM ameliorate healing of corneal ulcers with having a superior amelioration effect to EXs. The superior effect of EXs duetoanti-apoptotic, anti-inflammatory, and anti-oxidative.
PubDate: Wed, 08 Feb 2023 22:00:00 +010
- Effects of chronic uncontrolled hyperglycemia on neuroglial population of
CA3 region of ...
Abstract: Introduction: Altered function of astrocytes has been noticed in diabetes mellitus type1.Aims: this study was carried out to determine the effects of chronic uncontrolled hyperglycemia on neuroglial elements of the CA3 region of hippocampus. Materials & Methods: diabetes was induced in adult male wistar rats by application of streptozotocin (60mg/kg). After 8 weeks ,the hippocampi were removed and the number of astrocytes and degenerated neurons in CA3 were studied using transmission electron microscopy. Results: The astrocytes exhibited structural changes, including reduced electron density of the nucleus, electro-lucent heterochromatin, and vacuolated cytoplasm. The mean number of astrocytes in the CA3 region of diabetic group (7±2) showed a significant increase compared to the control group (P
PubDate: Tue, 07 Feb 2023 22:00:00 +010
- Gold Nanoparticles Alleviate Meloxicam Induced Toxicity in Adult Male Rat
Spleen through ...
Abstract: Background: Meloxicam is an analgesic with higher selective inhibition of cyclooxygenase 2 (COX-2). COX-2 inhibition induces oxidative stress. Gold nanoparticles (AuNPs) have several medical applications in diagnosing and treating diseases and have potent free radical scavenging properties.Objective: This study was conducted to assess the possible therapeutic effect of AuNPs on meloxicam-induced splenic toxicity at different time points. Materials and methods: Forty-five rats were used in this experiment and were divided into eight groups: group I; the control group. Group II received AuNPs for 2 weeks. Groups III and IV received meloxicam for 2 weeks and 2 months respectively. Groups V and VI received AuNPs for 2 weeks after receiving meloxicam for 2 weeks and 2 months respectively. Groups VII and VIII received meloxicam for two weeks and 2 months respectively followed by cessation of treatment for 2 weeks. Both meloxicam and AuNPs were injected daily intraperitoneally in a dose of 15mg/kg and 50 ul respectively. Histological changes, AuNPs localization in the spleen by silver nitrate, PCNA immunoexpression to detect cellular proliferation, and LC3 and p62 for detecting autophagy activation were studied.Results: Time-dependent degenerative histological changes and increased PCNA, LC3, and p62 expression were observed after meloxicam treatment. However, AuNPs ameliorated these changes.Conclusion: AuNPs have a therapeutic role against the toxic effects of meloxicam in the spleen which may be due to their antioxidant activity, in addition to activation of autophagy.
PubDate: Mon, 16 Jan 2023 22:00:00 +010
- Role of Botulinum Toxin A (Botox) as a New Modality in Induced Rhematoid
Arthritis Versus ...
Abstract: Introduction: Rheumatoid arthritis (RA) is defined as a chronic immune-mediated disease and the Botox is tried to be a new treatment. The aim of our work to compare the ameliorating actions of the peri-articular Botox as a new modality and the systematic corticosteroids on the rheumatoid arthritis in the adult albino rats. Materials and methods: Rats were randomly allocated into 5 weight-matched groups, each of 5 rats; Group 1: ten rats were divided into the negative control were left without any intervention and the positive control were injected intra-articularly with saline, Group 2 induced RA by injecting rats with Freund's Complete Adjuvant (CFA), Group 3 were injected with Botox together with CFA and Group 4 were injected with dexamethasone (DEX) with CFA. Results: the RA induced rats showed significant improvement histologically, biochemically and radiologically when given corticosteroids with mild amelioration when given Botox. Conclusion: we have concluded that the use of Botox and dexamethasone were effective therapies of the RA with the priority to dexamethasone in the management of the RA.
PubDate: Sat, 27 Aug 2022 22:00:00 +010
- Dose – Related Amiodarone induced Thyrotoxicity in Adult Albino Rat
and its Possible ...
Abstract: : Introduction: Amiodarone (AMN) is one of the most common anti-arrhythmic drugs having many harmful effects on many organs such as the thyroid gland. The aim of the present study is to delineate the possible protective action of vitamin E to ameliorate the AMN induced thyrotoxicity. Materials and methods: 20 rats were utilized and divided into group I were given no medications, group II were given half the therapeutic dose of amiodarone, group III were given the therapeutic dose of amiodarone orally and group IV were given the therapeutic dose of amiodarone and vitamin E. after 3 weeks, all rats were sacrificed and the thyroids were examined histologically and histochrmically for Bax. The sera were analyzed for the inflammatory markers including CRP and P53. Results: the thyroids showed amiodarone related histological and histochemical alterations with hormonal and inflammatory disturbances. It was concluded that vitamin E could reduce the amiodarone induced thyrotoxicity.
PubDate: Wed, 10 Aug 2022 22:00:00 +010
- The therapeutic potential of exosomes derived from mesenchymal stem cells
in experimentally ...
Abstract: Background and objectives: Cerebrovascular complications of hypertension are highly dangerous. In recent studies, exosomes have been widely used in several disease research areas, including hypertension research. Mesenchymal stem cells (MSCs) release high levels of exosomes. Therefore, we investigated the role of MSC-derived exosomes in alleviating hypertension-induced changes in the cerebral cortex of a rat model. Methods: A total of 30 rats were assigned to control, hypertensive, and exosome-treated groups which received 100 µg MSC-derived exosomes total protein via tail vein. Tissue samples were examined for gene expression using real-time quantitative polymerase chain reaction (RT-qPCR) and light and electron microscopy. Results and conclusion: Exosome treatment recovered blood vessels, neural cells and blood-brain barrier (BBB) alterations as verified by upregulated endothelial nitric oxide synthase (eNOS) and AMP-activated protein kinase (AMPK) mRNA, downregulated α-smooth muscle actin (α-SMA) mRNA, and enhanced angiogenic factors, miRNA-222 and Tie2 protein. Exosomes exerted anti-apoptotic effects by increasing Bcl-xl expression and decreasing caspase 3 protein levels in immune histochemical sections. The anti-inflammatory potential of exosomes was indicated by reduced IL-1β mRNA and microglia activation factor Iba1 protein levels. Neuronal protection was supported by upregulated miRNA-133b and calbindin D28K (CB) protein levels. Moreover, the astrocyte vascular feet protein aquaporin (AQP4) was downregulated. MSC-derived exosomes may be considered a novel strategy for treating cerebral hypertension complications.
PubDate: Fri, 01 Jul 2022 22:00:00 +010
- Cisplatin - induced Retinotoxicity in Adult Male Albino Rat and the
ameliorating Role of ...
Abstract: Background: Cisplatin (CP) is a main chemotherapy but cause damage on different organs. Aim of the work: the current study assessed Cisplatin’s effect on retina and the protective role of N-acetylcysteine (NAC). Material and methodes: the experiment was done on 30 male adult albino rats divided into three groups as following; control (Group I), Cisplatin-treated group (single intraperitoneal injection (IP) of CP 7 mg/kg , Group II), N- acetylcysteine-treated group (single IP of CP 7 mg/kg+ orally NAC 200 mg/kg/ 14 d, Group III. On day 14 of Cisplatin administration, tissue samples were collected for histobiochemical and histomorphometrical analysis. Results: The results detected that CP lead to a significant increase in MDA level and decrease of total antioxidant and eNos levels in retinal tissue as compared to other groups. Moreover, CP caused histopathological degeneration in the retina while NAC could improve it. Conclusion: CP had toxic effects on retina with modulating effect of NAC.
PubDate: Mon, 07 Mar 2022 22:00:00 +010
- Evaluation of Nandrolone Decanoate Effects on Sinoatrial Node in
Experimental Rat Model ...
Abstract: Background: Nandrolone decanoate (NA) is one of the anabolic steroids used medically and abused by athletes but hasseveral harmful effects.Aim: Evaluate the effect of nandrolone decanoate on sinoatrial node structure of albino rat and the effect of its withdrawal.Materials and Methods: Thirty adult albino rats were divided into three groups each containing ten rats. Group I (control): tenrats were divided into the negative control was left untreated and the positive control was injected by castor oil, twice weekly/8weeks. Group II (NA group): ten rats were injected by NA 5 mg/kg twice/week/8 weeks. Group III (recovery group): ten ratswere injected by NA 5 mg/kg twice/week /8 weeks, then were left 12 weeks to evaluate recovery. At the end, the sinoatrial nodewere dissected out, and subjected to histological and immunohistochemical examination.Results: Examination of right atrial sections of NA injected group showed wide separation of sinoatrial node structure anddisordered cell arrangement. P cell degeneration with increased cytoplasmic vacuoles was noted. Some cardiomyocytesexhibited degenerative changes including wavy sarcoplasm and fragmented pyknotic nuclei. After discontinuation of NA, thesinoatraial node did not regain its normal architecture. Mean area percentage % of collagen fiber deposition, SYN and iNOSimmunoexpressing in NA injected group was significantly increased relative to control group which did not recovered afterdrug withdrawal.Conclusion: Use of NA caused serious changes in sinoatrial node tissue which will threaten life of their users especially theathletes. Thus, NA must be administered only under medical supervision.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- Harmful Impacts of Bisphenol A on the Prostate of Adult Albino Rat and the
Possible Role of ...
Abstract: Introduction: Huge amounts of bisphenol A (BPA) are manufactured all over the world. The prostate is the major accessorysex gland of mammalian males. BPA can be toxic to prostatic tissues.Objectives: Investigate the impact of BPA on the prostate gland of adult male albino rats and the possibility of recovery.Materials and Methods: Thirty adult male albino rats (180-220 g) were assigned into three groups. Control group: received1mL of corn oil via gavage once daily for 8 weeks; BPA group: given 50 mg/kg of BPA in 1mL corn oil orally/ day for 8 weeks;Recovery group: given BPA the same manner as in BPA group and held without treatment for another 4 weeks. At the end ofthe study, blood was collected to measure serum testosterone. The prostate gland was removed and prepared for histologicaland immunohistochemical analysis.Results: In the BPA group, the testosterone level dropped significantly. Irregularity of prostatic acini; thickening, andhyperplasia of the prostatic epithelium; abundant stroma with congested blood vessels were seen in hematoxylin and eosin(H&E)-stained sections. Morphometry revealed that the epithelial height, number of proliferating cell nuclear antigen (PCNA)positive cells, and the area percentage of collagen were significantly higher while the acinar surface area, acinar perimeter,and the optical density (OD) of androgen receptors (AR) in epithelial cells were significantly lower. These changes partiallyresolved after stopping BPA treatment.Conclusion: The Prostate gland of adult rats can partially recover from the harmful impacts of bisphenol A.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- Histological Study on the Effect of Curcumin and Curcumin Nanoparticles on
Cadmium-Induced ...
Abstract: Background: Cadmium (Cd) is a non-essential heavy metal that is toxic to humans. Liver damage is one of chronic Cdexposure's most serious side effects. Curcumin has antioxidant and anti-inflammatory characteristics that make it goodpreventive therapy. Unfortunately, it has poor bioavailability due to its low solubility in aqueous solutions. However, itsnanoparticle formulations improve absorption by 10–14 times. Therefore, the present study was performed to evaluate thepossible protective effect of curcumin and nanocurcumin on Cd-induced liver damage in adult male albino rats.Materials and Methods: Forty-two male albino rats were used in this study. Rats were divided into 6 main groups. Cd-treatedgroup received 5mg /kg Cd dissolved in saline orally, once daily alone or associated either curcumin or nanocurcumin dissolvedin phosphate buffer in a dose 100mg /kg, orally once daily for 28 days. The appropriate controls were included. Animals werescarified and livers were harvested and processed for histological, immunohistochemical and morphometric assessments.Results: Cd caused damage to liver tissues in the form of blood sinusoid congestion and hepatocyte vacuolation with pyknoticnuclei. Moreover, there was inflammatory cell infiltration and increased collagen deposition. Immunohistochemistry revealeda strong positive Bax immunoreactivity in cadmium group. Oral administration of curcumin and nanocurcumin significantlyattenuated hepatotoxicity with a concomitant reduction in Bax immunoreactivity.Conclusion: Administration of curcumin and nanocurcumin demonstrated beneficial effects on Cd-induced hepatic histologicalalterations. Moreover, nano curcumin administration showed a more ameliorative effect on the histological structure of Cdinducedhepatic toxicity.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- Therapeutic Efficacy of Melatonin Pretreated Bone Marrow Mesenchymal Stem
Cells Versus ...
Abstract: Background: Diabetic cardiomyopathy (DCM) is a common condition that is associated with morbidity and mortality. Withthe medical advancement in cell treatment, stem cell therapy has a potential therapeutic strategy for DCM.Objectives: We aim to evaluate the possible therapeutic effects of Mesenchymal stem cells (MSCs) versus melatonin (MLT)preconditioned-MSCs in induced diabetic cardiomyopathy in rats.Materials and Methods: Forty-five male adult albino rats were divided into four groups. Group I: Control group. Group < br />II: Diabetic group: Rats received single intraperitoneal injection of streptozotocin STZ (50 mg/kg body weight). Group < br />III: DC treated with MSCs. Group IV: DC treated with MLT preconditioned-MSCs. Histological, ultrastructural andimmunohistochemical studies were performed on left ventricle myocardium. We also estimated the survival of MLTpreconditionedMSCs in vitro. Bcl-2, Casp-3, interleukin 1 (IL-1), and interleukin 10 (IL-10) expression were measured usingreal-time PCR in tissue homogenates.Results: Our findings revealed a significant increase in immunohistochemical expression of apoptotic markers in the diabeticgroup, as well as a disruption of the normal cardiac histological ultrastructure. Melatonin improved MSCs survival in vitroand altered apoptotic markers. In addition, the melatonin-preconditioned MSC group showed a significant increase in B-celllymphoma 2 (Bcl-2) mRNA expression and a significant decrease in Casp-3. Enhanced immunomodulatory behavior wasobvious by a significant attrition of the mRNA expression of IL-1β (inflammatory-agonist) and a significant altitude of IL-10(inflammatory-antagonist).Conclusion: The melatonin-preconditioning of MSCs enhance their survival and immunomodulatory activities and preciselyrestored cardiac histology. Thus, it unveils an encouraging interference of DC.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- The Beneficial Effects of Lipoic Acid Versus Coenzyme Q10 on
Arginine-Induced Acute ...
Abstract: Background: Acute pancreatitis (AP) is a self-limiting condition to a widespread, deadly multi-organ failure that can resultin death.Objectives: To compare the protective effect of alpha lipoic acid (ALA) and Coenzyme (Q10) in an experimental rat modelof L-arginine-induced AP.Materials (Subjects): Forty adult male albino rats were randomized equally into 4 groups: (i) The control group; (ii) The APgroup received L-Arginine by intraperitoneal (IP) injection in two doses of 2 g/kg body weight each, 1 hour apart, (iii) TheALA+AP group was injected with L-Arginine and intramuscular (IM) injection of ALA in two doses of 60mg/kg body weight;1 hour before L-arginine injection and 24 hours after the second dose of L-arginine; (iii) The Coenzyme Q10+AP group wasinjected with L-Arginine and IM injection of Q10 in two doses of 30mg/kg body weight; 1 hour before L-arginine injection and24 hours after the second dose of L-arginine. Histological, immunohistochemical for HSP70 and NF-κB, and morphometricstudies were done followed by statistical analysis.Results: AP group showed significant distortion of the pancreatic acini with obvious cellular damage while those treated byALA and Coenzyme Q 10 especially ALA showed significant pancreatic tissue improvement as shown by HSP70 and NF-κBimmunoexpressing.Conclusions: ALA and Q 10 therapy proved a clear protective effect in suppressing experimentally generated AP in malealbino rats, but the improvement was more obvious with ALA.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- The Possible Protective Role of Tannic Acid against Monosodium
Glutamate-Induced Pancreatic and ...
Abstract: Background: Monosodium Glutamate (MSG) is a common flavor enhancer that has several toxic effects on different bodyorgans. Tannic acid (TA) is a naturally occurring antioxidant component with several pharmacological properties.Objectives: The present study was conducted to assess the possible protective role of TA on MSG-induced hepatic andpancreatic toxicity.Materials and Methods: 40 adult male albino rats were divided into 4 equal groups. Group I was the control group, group IIreceived TA, group III received MSG, and group IV received TA + MSG for 4 weeks. TA and MSG were received in a doseof 100mg/kg BW and 2g/kg BW respectively. At the end of the study, the evaluation was done by biochemical analysis andhistopathology. Immunohistochemistry was used to measure BAX antibody and insulin expression.Results: MSG increased the levels of pancreatic enzymes; amylase and lipase enzymes, as well as blood sugar levels. Liverenzymes were also increased. Histologically, degenerative changes were observed in the liver and pancreas with increased isletssurface area. MSG increased the expression of the apoptotic marker BAX and decreased β-cells percentage. Co-administrationof TA with MSG attenuated these degenerative effects.Conclusion: MSG has toxic effects on the liver and pancreas leading to increased blood glucose levels. TA has an antioxidantrole against MSG toxicity with a reduction of blood glucose levels.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
- Histological and Biochemical Study on the Estrogen Role in
Indomethacin-induced Gastric Ulcer ...
Abstract: In the article titled “Histological and Biochemical Study on the Estrogen Role in Indomethacin-induced Gastric Ulcer ofMenopausal Rats”, published on pages 146-161, Issue 2, Volume 2 of Journal of Medical Histology[1], the English title of thearticle was written incorrectly as “Histological and Biochemical Study on the Estrogen Role in Indomethacin-induced GastricUlcer of Menopausal Rats” instead of “Estrogen supplementation role in the treatment of indomethacin-induced gastric ulcerof ovarectomized rat (Histological and Biochemical study)”.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
Issue No: Vol. 2 (2021)
- The role of retinoids in acute renal damage associated with acetic acid
induced ulcerative ...
Abstract: In the article titled “The role of retinoids in acute renal damage associated with acetic acid induced ulcerative colitis inadult male rats: Histological and biochemical study”, published on pages 44–58, Issue 1, Volume 3 of Journal of MedicalHistology[1], the English title of the article was written incorrectly as “The role of retinoids in acute renal damage associatedwith acetic acid induced ulcerative colitis in adult male rats: Histological and biochemical study” instead of “Histological andBiochemical study of rat renal cortex in induced ulcerative colitis with evaluating the potential role of retinoids”.
PubDate: Tue, 30 Nov 2021 22:00:00 +010
Issue No: Vol. 3 (2021)
