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JCO Precision Oncology
Number of Followers: 8

Full-text available via subscription

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ISSN (Online) 2473-4284
Published by LWW Wolters Kluwer

[297 journals]

Targeting Anaplastic Lymphoma Kinase in GI Primary Malignancies
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  Authors: Jerold Loh, Yvonne Li En Ang, Amit Jain, Joe Yeong, Raghav Sundar
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-08-08T07:00:00
  DOI: 10.1200/PO.22.00208
Soft Tissue Leiomyosarcoma With Microsatellite Instability, High Tumor
Mutational Burden, and Programmed Death Ligand-1 Expression Showing
Pathologic Complete Response to Pembrolizumab: A Case Report
Open Access Article
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  Authors: Timothy Kwang Yong Tay, Joe Poh Sheng Yeong, Eileen Xueqin Chen, Xin Xiu Sam, Johnathan Xiande Lim, Jason Yongsheng Chan
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-08-08T07:00:00
  DOI: 10.1200/PO.22.00068
Multianalyte Prognostic Signature Including Circulating Tumor DNA and
Circulating Tumor Cells in Patients With Advanced Pancreatic
Adenocarcinoma
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  Authors: William J. Chapin, Jacob E. Till, Wei-Ting Hwang, Jennifer R. Eads, Thomas B. Karasic, Peter J. O'Dwyer, Charles J. Schneider, Ursina R. Teitelbaum, Janae Romeo, Taylor A. Black, Theresa E. Christensen, Colleen Redlinger Tabery, Amanda Anderson, Megan Slade, Michael LaRiviere, Stephanie S. Yee, Kim A. Reiss, Mark H. O'Hara, Erica L. Carpenter
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-08-08T07:00:00
  DOI: 10.1200/PO.22.00060
Phase II Study of Afatinib in Patients With Tumors With Human Epidermal
Growth Factor Receptor 2–Activating Mutations: Results From the National
Cancer Institute–Molecular Analysis for Therapy Choice ECOG-ACRIN Trial
(EAY131) Subprotocol EAY131-B
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  Authors: Philippe L. Bedard, Shuli Li, Kari B. Wisinski, Eddy S. Yang, Sewanti A. Limaye, Edith P. Mitchell, James A. Zwiebel, Jeffrey A. Moscow, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David R. Patton, P. Mickey Williams, Stanley R. Hamilton, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O'Dwyer, Alice P. Chen, Keith T. Flaherty
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-08-08T07:00:00
  DOI: 10.1200/PO.22.00165
An Approach to Solving the Complex Clinicogenomic Data Landscape in
Precision Oncology: Learnings From the Design of WAYFIND-R, a Global
Precision Oncology Registry
Open Access Article
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  Authors: Christophe Le Tourneau, Camille Perret, Allan Hackshaw, Jean-Yves Blay, Christoph Nabholz, Jan Geissler, Thy Do, Martina von Meyenn, Rodrigo Dienstmann
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-08-08T07:00:00
  DOI: 10.1200/PO.22.00019
Response to Alpelisib in an Adolescent With PIK3CA-Mutated Metastatic
Gastrointestinal Stromal Tumor
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  Authors: Sarah Cohen-Gogo, Nisha Kanwar, Furqan Shaikh, Reto M. Baertschiger, Adam Shlien, David Malkin, Juan Putra, Ailish Coblentz, Anita Villani, Abha A. Gupta, Daniel A. Morgenstern
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-08-02T07:00:00
  DOI: 10.1200/PO.22.00105
Lung Adenocarcinoma Associated With Germline EGFR R776H Variant: A Case
Report and Review of the Literature
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  Authors: Justin Lin Sovich, Tu Dan, Amber Gemmell, Cheyla Clark, Jeffrey Gagan, Jonathan E. Dowell
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-21T07:00:00
  DOI: 10.1200/PO.21.00559
Identification of KRASG12C Mutations in Circulating Tumor DNA in Patients
With Cancer
Open Access Article
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  Authors: Kyaw Z. Thein, Amadeo B. Biter, Kimberly C. Banks, Andrew W. Duda, Jennifer Saam, Jason Roszik, Filip Janku, Ferdinandos Skoulidis, John V. Heymach, Scott Kopetz, Funda Meric-Bernstam, David S. Hong
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-07-21T07:00:00
  DOI: 10.1200/PO.21.00547
DPYD*7 as a Predictor of Severe Fluoropyrimidine-Related Adverse Events
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  Authors: Mirjam de With, Gemma Brufau, Laila A. van den Berg, Femke M. de Man, Marija Trajkovic, Martine F. Thijs, Rob Castel, Henricus J. Vermeer, Samira el Bouazzaoui, Amber van Hemel, Maja Matic, Ron H. J. Mathijssen, Sander Bins, Ron H. N. van Schaik
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-07-21T07:00:00
  DOI: 10.1200/PO.22.00180
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-18T07:00:00
  DOI: 10.1200/PO.22.00356
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-18T07:00:00
  DOI: 10.1200/PO.22.00354
BRCA2 Alterations in Neuroendocrine/Small-Cell Carcinoma Prostate Cancer:
A Case Series
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  Authors: Lynn Symonds, Erik Konnick, Funda Vakar-Lopez, Heather H. Cheng, Michael T. Schweizer, Peter S. Nelson, Colin C. Pritchard, Bruce Montgomery
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-14T07:00:00
  DOI: 10.1200/PO.22.00091
Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment
Outcomes in Advanced Cancers
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  Authors: Mohamed A. Gouda, Helen J. Huang, Sarina A. Piha-Paul, S. Greg Call, Daniel D. Karp, Siqing Fu, Aung Naing, Vivek Subbiah, Shubham Pant, Derek J. Dustin, Apostolia M. Tsimberidou, David S. Hong, Jordi Rodon, Funda Meric-Bernstam, Filip Janku
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-07-14T07:00:00
  DOI: 10.1200/PO.21.00512
Cost-Effectiveness of Parallel Versus Sequential Testing of Genetic
Aberrations for Stage IV Non–Small-Cell Lung Cancer in the Netherlands
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  Authors: Henri B. Wolff, Elisabeth M.P. Steeghs, Zakile A. Mfumbilwa, Harry J.M. Groen, Eddy M. Adang, Stefan M. Willems, Katrien Grünberg, Ed Schuuring, Marjolijn J.L. Ligtenberg, Bastiaan B.J. Tops, Veerle M.H. Coupé
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-07-14T07:00:00
  DOI: 10.1200/PO.22.00201
Spontaneous Fluctuations of Tumor-Informed Circulating Tumor DNA at Low
Levels
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  Authors: Farshid Dayyani, Maheswari Senthil
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-14T07:00:00
  DOI: 10.1200/PO.22.00177
Reply to F. Dayyani et al
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  Authors: Pashtoon M. Kasi, Gordon Fehringer, Alexey Aleshin, Scott Kopetz
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-14T07:00:00
  DOI: 10.1200/PO.22.00275
CDK4/6 Inhibition With Anti–PD-1 Checkpoint Blockade Induces Major
Response in Aggressive Classic Kaposi Sarcoma After Previous Progression
on Anti-PD–1 Alone
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  Authors: Sminu Bose, Tristan Lee, Shaelyn Choi, Ladan Fazlollahi, Michael J. Rasiej, Gary K. Schwartz, Matthew Ingham
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-12T07:00:00
  DOI: 10.1200/PO.21.00550
Genomic Biomarkers and Genome-Wide Loss-of-Heterozygosity Scores in
Metastatic Prostate Cancer Following Progression on Androgen-Targeting
Therapies
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  Authors: Amado J. Zurita, Ryon P. Graf, Guillermo Villacampa, Kira Raskina, Ethan Sokol, Dexter Jin, Emmanuel S. Antonarakis, Gerald Li, Richard S. P. Huang, Irene Casanova-Salas, Ana Vivancos, Joan Carles, Jeffrey S. Ross, Alexa B. Schrock, Geoffrey R. Oxnard, Joaquin Mateo
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-07-12T07:00:00
  DOI: 10.1200/PO.22.00195
Germline De Novo Mutations as a Cause of Childhood Cancer
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  Authors: Wafaa M. Rashed, Erin L. Marcotte, Logan G. Spector
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Cancer Prevention
  Citation: JCO Precision Oncology
  PubDate: |2022-07-12T07:00:00
  DOI: 10.1200/PO.21.00505
DICER1-Associated Anaplastic Sarcoma of the Kidney With Coexisting
Activating PDGFRA D842V Mutations and Response to Targeted Kinase
Inhibitors in One Patient
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  Authors: Cristina R. Antonescu, Victor E. Reuter, Mary Lou Keohan, Sinchun Hwang, Ping Chi
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-07T07:00:00
  DOI: 10.1200/PO.21.00554
Durable Response to Combined Osimertinib and Pralsetinib Treatment for
Osimertinib Resistance Due to Novel Intergenic ANK3-RET Fusion in
EGFR-Mutated Non–Small-Cell Lung Cancer
Open Access Article
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  Authors: Edyta M. Urbanska, Jens B. Sørensen, Linea C. Melchior, Junia C. Costa, Eric Santoni-Rugiu
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-07-07T07:00:00
  DOI: 10.1200/PO.22.00040
Matched Molecular Profiling of Cell-Free DNA and Tumor Tissue in Patients
With Advanced Clear Cell Renal Cell Carcinoma
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  Authors: Ritesh R. Kotecha, Erika Gedvilaite, Ryan Ptashkin, Andrea Knezevic, Samuel Murray, Ian Johnson, Natalie Shapnik, Darren R. Feldman, Maria I. Carlo, Neil J. Shah, Marisa Dunigan, Kety Huberman, Ryma Benayed, Ahmet Zehir, Michael F. Berger, Marc Ladanyi, Dana W. Y. Tsui, Robert J. Motzer, Chung-Han Lee, Martin H. Voss
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-07-07T07:00:00
  DOI: 10.1200/PO.22.00012
Multidimensional Molecular Profiling of Metastatic Triple-Negative Breast
Cancer and Immune Checkpoint Inhibitor Benefit
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  Authors: Romualdo Barroso-Sousa, Juliet Forman, Katharine Collier, Zachary T. Weber, Tejas R. Jammihal, Katrina Z. Kao, Edward T. Richardson, Tanya Keenan, Ofir Cohen, Michael P. Manos, Ryan C. Brennick, Patrick A. Ott, F. Stephen Hodi, Deborah A. Dillon, Victoria Attaya, Tess O'Meara, Nancy U. Lin, Eliezer M. Van Allen, Scott Rodig, Eric P. Winer, Elizabeth A. Mittendorf, Catherine J. Wu, Nikhil Wagle, Daniel G. Stover, Sachet A. Shukla, Sara M. Tolaney
  Abstract: JCO Precision Oncology, Volume , Issue 6, July 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-07-07T07:00:00
  DOI: 10.1200/PO.21.00413
Social Genomics as a Framework for Understanding Health Disparities Among
Adolescent and Young Adult Cancer Survivors: A Commentary
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  Authors: Lauren V. Ghazal, Steve Cole, John M. Salsman, Lynne Wagner, Fenghai Duan, Ilana Gareen, Lauren Lux, Susan K. Parsons, Christabel Cheung, David M. Loeb, Pinki Prasad, Shira Dinner, Brad Zebrack
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.21.00462
Tumor Mutational Burden Is a Potential Predictive Biomarker for Response
to Immune Checkpoint Inhibitors in Patients With Advanced Biliary Tract
Cancer
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  Authors: Savannah S. Liddell, Sakti Chakrabarti, Grant A. Wintheiser, Tyler J. Zemla, Qian Shi, Sri Harsha Tella, Zhaohui Jin, Vanessa B. Wookey, Hind Hassan, Nguyen H. Tran, Mitesh J. Borad, Amit Mahipal
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.22.00003
PARP Inhibitor Insensitivity to BRCA1/2 Monoallelic Mutations in
Microsatellite Instability-High Cancers
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  Authors: Ethan S. Sokol, Dexter X. Jin, Alexander Fine, Sally E. Trabucco, Sophia Maund, Garrett Frampton, Luciana Molinero, Emmanuel S. Antonarakis
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.21.00531
Genomic Landscape of Advanced Solid Tumors in Circulating Tumor DNA and
Correlation With Tissue Sequencing: A Single Institution's Experience
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  Authors: Lorenzo Gerratana, Michael Movarek, Firas Wehbe, Neelima Katam, Devalingam Mahalingam, Jeannine Donahue, Ami Shah, Young K. Chae, Mary Mulcahy, Dean Tsarwhas, Victoria Villaflor, Aparna Kalyan, Maha Hussein, Jyoti Patel, Sunandana Chandra, Leonidas C. Platanias, William Gradishar, Massimo Cristofanilli, Amir Behdad
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.21.00289
Homologous Recombination Deficiency in Pancreatic Cancer: Poly
(ADP-ribose) Polymerase Inhibition, Checkpoint Inhibition, or a
Combination of Both'
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  Authors: Fergus Keane, Wungki Park, Eileen M. O'Reilly
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.22.00141
Reply to F. Keane et al
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  Authors: Vinod Ganju, Daniel Croagh, Joanne Lundy
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-30T07:00:00
  DOI: 10.1200/PO.22.00171
Checkpoint Inhibitor Immunotherapy to Treat Temozolomide-Associated
Hypermutation in Advanced Atypical Carcinoid Tumor of the Lung
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  Authors: Fangdi Sun, James P. Grenert, Lisa Tan, Jessica Van Ziffle, Nancy M. Joseph, Claire K. Mulvey, Emily Bergsland
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-23T07:00:00
  DOI: 10.1200/PO.22.00009
RAD51B Harbors Germline Mutations Associated With Pancreatic Ductal
Adenocarcinoma
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  Authors: Fanfan Xie, Ding Ding, Cong Lin, Dea Cunningham, Michael Wright, Ammar A. Javed, Nilo Azad, Valerie Lee, Ross Donehower, Ana De Jesus-Acosta, Dung T. Le, Michael Pishvaian, Eun Ji Shin, Anne Marie Lennon, Mouen Khashab, Vikesh Singh, Alison P. Klein, Nicholas J. Roberts, Amy Hacker-Prietz, Thomas McPhaul, Richard A. Burkhart, William R. Burns, Amol Narang, Atif Zaheer, Elliot K. Fishman, Elizabeth D. Thompson, Robert Anders, Jun Yu, Jin He, Christopher L. Wolfgang, Lei Zheng, Dongbing Liu, Kui Wu, Daniel A. Laheru
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-06-23T07:00:00
  DOI: 10.1200/PO.21.00404
Disparities in Biomarker Testing and Clinical Trial Enrollment Among
Patients With Lung, Breast, or Colorectal Cancers in the United States
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  Authors: Debora S. Bruno, Lisa M. Hess, Xiaohong Li, Eric Wen Su, Monaliben Patel
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Diagnostics
  Citation: JCO Precision Oncology
  PubDate: |2022-06-23T07:00:00
  DOI: 10.1200/PO.21.00427
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-23T07:00:00
  DOI: 10.1200/PO.22.00301
Gamma Secretase Inhibition for a Child With Metastatic Glomus Tumor and
Activated NOTCH1
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  Authors: Ellen Zhang, Amber Miller, Catherine Clinton, Kylene DeSmith, Stephan D. Voss, Jon C. Aster, Alanna J. Church, Reza Rahbar, Nadezhda Eberhart, Katherine A. Janeway, Steven G. DuBois
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-22T07:00:00
  DOI: 10.1200/PO.22.00099
Clinical and Genomic Characterization of Bladder Carcinomas With Glandular
Phenotype
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  Authors: Nima Almassi, Karissa Whiting, Antoun Toubaji, Andrew T. Lenis, Emmet J. Jordan, Helen Won, Ashley M. Regazzi, Ying-Bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Irina Ostrovnaya, Eugene J. Pietzak, Eugene K. Cha, Alvin C. Goh, Timothy F. Donahue, Harry W. Herr, S. Machele Donat, Guido Dalbagni, Bernard H. Bochner, Min Yuen Teo, Samuel A. Funt, Jonathan E. Rosenberg, Victor E. Reuter, Dean F. Bajorin, David B. Solit, Hikmat Al-Ahmadie, Gopa Iyer
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-06-22T07:00:00
  DOI: 10.1200/PO.21.00392
Programmatic Efforts Increase Adoption of Genomic Precision Medicine in
Cancer Care in a Community Cancer Center
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  Authors: Sourat Darabi, David Braxton, Jeanne Homer, Taylor Brodie, Dori Holnagel, Burton Eisenberg, Michael J. Demeure
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-06-22T07:00:00
  DOI: 10.1200/PO.22.00090
Missing Companion Diagnostic for US Food and Drug
Administration–Approved Hematological and Oncological Drugs
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  Authors: Jan Trøst Jørgensen
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-16T07:00:00
  DOI: 10.1200/PO.22.00100
Locoregionally Advanced, BRAF V600L–Positive, Mucosal Melanoma of the
Hypopharynx Treated With a Combination of BRAF and MEK Inhibitors
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  Authors: Giovanni Lampasona, Jonathan Noujaim, Olga Gologan, Jeremie Berdugo, Anastasios Maniakas
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-16T07:00:00
  DOI: 10.1200/PO.21.00561
Reply to T. Ménard
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  Authors: Nahed Jalloul, Shridar Ganesan, Judy E. Garber, Hossein Khiabanian
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-16T07:00:00
  DOI: 10.1200/PO.22.00188
Inferences of Mutational Status for Variants Detected From Tumor-Only
Sequencing—A Quality Assurance Strategy
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  Authors: Timothé Ménard
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-16T07:00:00
  DOI: 10.1200/PO.22.00125
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-16T07:00:00
  DOI: 10.1200/PO.22.00296
A Three-Gene Signature Predicts Response to Selinexor in Multiple Myeloma
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  Authors: Paula Restrepo, Sherry Bhalla, Yogita Ghodke-Puranik, Adolfo Aleman, Violetta Leshchenko, David T. Melnekoff, Sarita Agte, Joy Jiang, Deepu Madduri, Joshua Richter, Shambavi Richard, Ajai Chari, Hearn Jay Cho, Sundar Jagannath, Christopher J. Walker, Yosef Landesman, Alessandro Laganà, Samir Parekh
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-06-15T07:00:00
  DOI: 10.1200/PO.22.00147
Molecular Characterization of Mesothelioma: Impact of Histologic Type and
Site of Origin on Molecular Landscape
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  Authors: Ibiayi Dagogo-Jack, Russell W. Madison, Jochen K. Lennerz, Kuei-Ting Chen, Julia F. Hopkins, Alexa B. Schrock, Lauren L. Ritterhouse, Ashley Lester, Keith A. Wharton Jr, Mari Mino-Kenudson, Natalie Danziger, Yin P. Hung, Douglas A. Mata, Jeffrey S. Ross
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-06-15T07:00:00
  DOI: 10.1200/PO.21.00422
Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type
2 Iodothyronine Deiodinase
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  Authors: Laura Boucai, Federico Salas-Lucia, Gnana P. Krishnamoorthy, Eric Sherman, Charles M. Rudin, Alexander Drilon, Antonio C. Bianco, James A. Fagin
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-06-15T07:00:00
  DOI: 10.1200/PO.21.00496
Minimal Residual Disease–Guided Intermittent Dosing in Patients With
Cancer: Successful Treatment of Chemoresistant Anaplastic Large Cell
Lymphoma Using Intermittent Lorlatinib Dosing
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  Authors: Petra Pokorna, Giannoula Lakka Klement, Alzbeta Vasikova, Veronika Kanderova, Marta Jezova, Kristyna Noskova, Peter Mudry, Michal Kyr, Tomas Merta, Viera Bajciova, Zdenka Krenova, Hana Palova, Dalibor Valik, Lenka Zdrazilova Dubska, Ondrej Slaby, Jaroslav Sterba
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-14T07:00:00
  DOI: 10.1200/PO.21.00525
Primary Clonal Loss of Mismatch Repair Protein on Immunohistochemistry: A
Pattern of Abnormality That Warrants Genetic Workup
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  Authors: Christine Orr, Chiyun Wang, Canan Firat, Louise C. Connell, Margaret R. Sheehan, Efsevia Vakiani, Zsofia K. Stadler, Jinru Shia
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-14T07:00:00
  DOI: 10.1200/PO.22.00111
Severe Lactic Acidosis Complicated by Insulin-Resistant Hyperosmolar
Hyperglycemic Syndrome in a Patient With Metastatic Breast Cancer
Undergoing AKT-Inhibitor Therapy
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  Authors: Maria I. Stamou, Christopher Chen, Seth A. Wander, Jeffrey G. Supko, Dejan Juric, Aditya Bardia, Deborah J. Wexler
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-14T07:00:00
  DOI: 10.1200/PO.21.00428
MET/HGF Coexpression as a Novel Predictive Biomarker for Response to MET
Inhibitor Therapy in a Case of Psammomatous Melanotic Schwannoma
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  Authors: Jenny J. Li, Xiaoling Zhang, Neil Sankar, Lynn Espiritu, Sanjeev Redkar, Guo-liang Yu, Sani H. Kizilbash
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.22.00096
Concurrent Germline BRCA1/2 and Mismatch Repair Mutations in Young-Onset
Pancreatic and Colorectal Cancer: The Importance of Comprehensive Germline
and Somatic Characterization to Inform Therapeutic Options
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  Authors: Muhammet Ozer, Megha Ranganathan, Nicolas Lecomte, Juan M. Schvartzman, Henry S. Walch, Walid K. Chatila, Jungeui Hong, Maria I. Carlo, Michael F. Walsh, Margaret Sheehan, Diana Mandelker, Ozge Ceyhan-Birsoy, Anna Maio, Yelena Kemel, Christine A. Iacobuzio-Donahue, Eileen M. O'Reilly, Kenneth H. Yu
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.21.00560
Clinical, Genomic, and Transcriptomic Data Profiling of Biliary Tract
Cancer Reveals Subtype-Specific Immune Signatures
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  Authors: Kabir Mody, Prerna Jain, Sherif M. El-Refai, Nilofer S. Azad, Daniel J. Zabransky, Marina Baretti, Rachna T. Shroff, R. Katie Kelley, Anthony B. El-Khouiery, Adam J. Hockenberry, Denise Lau, Gregory B. Lesinski, Mark Yarchoan
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.21.00510
Reply to E. Rosenbaum et al
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  Authors: Joseph Paul Eder
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.22.00136
Interpreting Nonrandomized Clinical Trial Data in Low-Grade Sarcoma:
Differentiating Clinical Benefit From Indolent Disease Is Key
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  Authors: Evan Rosenbaum, Sujana Movva, Ciara Kelly
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.22.00092
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-06-08T07:00:00
  DOI: 10.1200/PO.22.00269
Germline Variant Spectrum Among African American Men Undergoing Prostate
Cancer Germline Testing: Need for Equity in Genetic Testing
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  Authors: Veda N. Giri, Rebecca Hartman, Mary Pritzlaff, Carrie Horton, Scott W. Keith
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-06-06T07:00:00
  DOI: 10.1200/PO.22.00234
Cell-Free Tumor DNA Dominant Clone Allele Frequency Is Associated With
Poor Outcomes in Advanced Biliary Cancers Treated With Platinum-Based
Chemotherapy
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  Authors: Pedro Luiz Serrano Uson Junior, Umair Majeed, Jun Yin, Gehan Botrus, Mohamad Bassam Sonbol, Daniel H. Ahn, Jason S. Starr, Jeremy C. Jones, Hani Babiker, Samantha R. Inabinett, Natasha Wylie, Ashton W.R. Boyle, Tanios S. Bekaii-Saab, Gregory J. Gores, Rory Smoot, Michael Barrett, Bolni Nagalo, Nathalie Meurice, Natalie Elliott, Joachim Petit, Yumei Zhou, Mansi Arora, Chelsae Dumbauld, Oumar Barro, Alexander Baker, James Bogenberger, Kenneth Buetow, Aaron Mansfield, Kabir Mody, Mitesh J. Borad
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-06-06T07:00:00
  DOI: 10.1200/PO.21.00274
Longitudinal Shifts of Solid Tumor and Liquid Biopsy Sequencing
Concordance in Metastatic Breast Cancer
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  Authors: Minetta C. Liu, Matthew MacKay, Matthew Kase, Aneta Piwowarczyk, Christine Lo, Jeff Schaeffer, Justin D. Finkle, Christopher E. Mason, Nike Beaubier, Kimberly L. Blackwell, Ben Ho Park
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-06-06T07:00:00
  DOI: 10.1200/PO.21.00321
Biomarkers for Cyclin-Dependent Kinase 4/6 Inhibitors in the Treatment of
Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor
2-Negative Advanced/Metastatic Breast Cancer: Translation to Clinical
Practice
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  Authors: Tam Binh V. Bui, Boudewijn M.T. Burgering, Andrei Goga, Hope S. Rugo, Laura J. van ‘t Veer
  Abstract: JCO Precision Oncology, Volume , Issue 6, June 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-06-06T07:00:00
  DOI: 10.1200/PO.21.00473
Genomic Evolution and Personalized Therapy of an Infantile Fibrosarcoma
Harboring an NTRK Oncogenic Fusion
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  Authors: Anne Thorwarth, Kerstin Haase, Claudia Röefzaad, Kristian W. Pajtler, Kathrin Schramm, Kathrin Hauptmann, Anke Behnke, Christian Vokuhl, Thomas Elgeti, Alexander Gratopp, Johannes H. Schulte, Monika Scheer, Pablo Hernáiz Driever, Karsten Nysom, Angelika Eggert, Anton G. Henssen, Hedwig E. Deubzer
  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-05-25T07:00:00
  DOI: 10.1200/PO.21.00283
Utility of Homologous Recombination Deficiency Biomarkers Across Cancer
Types
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  Authors: Shiro Takamatsu, J.B. Brown, Ken Yamaguchi, Junzo Hamanishi, Koji Yamanoi, Hisamitsu Takaya, Tomoko Kaneyasu, Seiichi Mori, Masaki Mandai, Noriomi Matsumura
  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-05-25T07:00:00
  DOI: 10.1200/PO.22.00085
Retraction
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  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-05-25T07:00:00
  DOI: 10.1200/PO.22.00124
Tumor and Constitutional Sequencing for Neurofibromatosis Type 1
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  Authors: Schuyler Tong, W. Patrick Devine, Joseph T. Shieh
  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-05-18T07:00:00
  DOI: 10.1200/PO.21.00540
Clustered 8-Oxo-Guanine Mutations and Oncogenic Gene Fusions in
Microsatellite-Unstable Colorectal Cancer
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  Authors: Russell W. Madison, Xiaoju Hu, Vivek Ramanan, Zhuxuan Xu, Richard S.P. Huang, Ethan S. Sokol, Garrett M. Frampton, Alexa B. Schrock, Siraj M. Ali, Shridar Ganesan, Subhajyoti De
  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-05-18T07:00:00
  DOI: 10.1200/PO.21.00477
Phase II Study of Lorlatinib in Patients With Anaplastic Lymphoma
Kinase–Positive Lung Cancer and CNS-Specific Relapse
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  Authors: Ibiayi Dagogo-Jack, Geoffrey R. Oxnard, Makenzi Evangelist, Subba R. Digumarthy, Jessica J. Lin, Justin F. Gainor, John F. Murphy, Michael S. Rabin, Rebecca S. Heist, Alona Muzikansky, Alice T. Shaw
  Abstract: JCO Precision Oncology, Volume , Issue 6, May 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-05-18T07:00:00
  DOI: 10.1200/PO.21.00522
Effects of Metastatic Sites on Circulating Tumor DNA in Patients With
Metastatic Colorectal Cancer
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  Authors: Hideaki Bando, Yoshiaki Nakamura, Hiroya Taniguchi, Manabu Shiozawa, Hisateru Yasui, Taito Esaki, Yoshinori Kagawa, Tadamichi Denda, Taroh Satoh, Kentaro Yamazaki, Yu Sunakawa, Takeshi Kato, Masahiro Goto, Satoshi Yuki, Tomohiro Nishina, Eiji Oki, Eiji Shinozaki, Nobuhisa Matsuhashi, Naoki Takahashi, Akihito Tsuji, Koushiro Ohtsubo, Masashi Wakabayashi, Takashi Ikeno, Masayuki Hata, Justin I. Odegaard, Takayuki Yoshino
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-05-11T07:00:00
  DOI: 10.1200/PO.21.00535
Negative Ultraselection of Patients With RAS/BRAF Wild-Type,
Microsatellite-Stable Metastatic Colorectal Cancer Receiving
Anti–EGFR-Based Therapy
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  Authors: Giovanni Randon, Giulia Maddalena, Marco Maria Germani, Chiara Carlotta Pircher, Paolo Manca, Francesca Bergamo, Mirella Giordano, Caterina Sposetti, Aldo Montagna, Guglielmo Vetere, Luca Zambelli, Cosimo Rasola, Alessandra Boccaccino, Filippo Pagani, Margherita Ambrosini, Marco Massafra, Gabriella Fontanini, Massimo Milione, Matteo Fassan, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-05-11T07:00:00
  DOI: 10.1200/PO.22.00037
Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has
a Measurable Impact on Clinical Care
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  Authors: Ryan J. Summers, Sharon M. Castellino, Christopher C. Porter, Tobey J. MacDonald, Gargi D. Basu, Szabolcs Szelinger, Manoj K. Bhasin, Thomas Cash, Alexis B. Carter, Robert Craig Castellino, Jason R. Fangusaro, Sarah G. Mitchell, Melinda G. Pauly, Bojana Pencheva, Daniel S. Wechsler, Douglas K. Graham, Kelly C. Goldsmith
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-05-11T07:00:00
  DOI: 10.1200/PO.21.00451
Progression-Free Survival in Patients With Cholangiocarcinoma With or
Without FGF/FGFR Alterations: A FIGHT-202 Post Hoc Analysis of Prior
Systemic Therapy Response
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  Authors: Kristen Bibeau, Luis Féliz, Christine F. Lihou, Haobo Ren, Ghassan K. Abou-Alfa
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-05-11T07:00:00
  DOI: 10.1200/PO.21.00414
Activity of Pemigatinib in Pilocytic Astrocytoma and FGFR1N546K Mutation
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  Authors: Stephen Capone, Leena Ketonen, Shiao-Pei Weathers, Vivek Subbiah
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-05-04T07:00:00
  DOI: 10.1200/PO.21.00371
Genomic Features of Lung-Recurrent Hormone-Sensitive Prostate Cancer
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  Authors: Nicolette M. Fonseca, Kim Van der Eecken, Cameron Herberts, Sofie Verbeke, Sarah W.S. Ng, Nicolaas Lumen, Elie Ritch, Andrew J. Murtha, Cecily Q. Bernales, Elena Schönlau, Lisa Moris, Jo Van Dorpe, Matti Annala, Alexander W. Wyatt, Piet Ost
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-05-04T07:00:00
  DOI: 10.1200/PO.21.00543
Isocitrate Dehydrogenase Mutations in Cholangiocarcinoma: Still a Long
Road Ahead
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  Authors: Federico Nichetti, Monica Niger
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-05-04T07:00:00
  DOI: 10.1200/PO.22.00065
Reply to F. Nichetti et al
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  Authors: Grant Wintheiser, Tyler Zemla, Amit Mahipal
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-05-04T07:00:00
  DOI: 10.1200/PO.22.00131
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-04-28T07:00:00
  DOI: 10.1200/PO.22.00193
Distinct Neoadjuvant Chemotherapy Response and 5-Year Outcome in Patients
With Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor
2–Negative Breast Tumors That Reclassify as Basal-Type by the 80-Gene
Signature
Open Access Article
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  Authors: Pat W. Whitworth, Peter D. Beitsch, James V. Pellicane, Paul L. Baron, Laura A. Lee, Carrie L. Dul, Mary K. Murray, Mark A. Gittleman, Raye J. Budway, Rakhshanda Layeequr Rahman, Pond R. Kelemen, William C. Dooley, David T. Rock, Kenneth H. Cowan, Beth-Ann Lesnikoski, Julie L. Barone, Andrew Y. Ashikari, Beth B. Dupree, Shiyu Wang, Andrea R. Menicucci, Erin B. Yoder, Christine Finn, Kate Corcoran, Lisa E. Blumencranz, William Audeh
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-04-27T07:00:00
  DOI: 10.1200/PO.21.00463
ALK Inhibitors in Patients With ALK Fusion–Positive GI Cancers: An
International Data Set and a Molecular Case Series
Open Access Article
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  Authors: Margherita Ambrosini, Marzia Del Re, Paolo Manca, Andrew Hendifar, Alexander Drilon, Guilherme Harada, Anne Hansen Ree, Samuel Klempner, Gunhild Mari Mælandsmo, Kjersti Flatmark, Hege G. Russnes, James M. Cleary, Harshabad Singh, Elisa Sottotetti, Antonia Martinetti, Giovanni Randon, Andrea Sartore-Bianchi, Iolanda Capone, Massimo Milione, Maria Di Bartolomeo, Filippo Pietrantonio
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-04-27T07:00:00
  DOI: 10.1200/PO.22.00015
Homologous Recombination Repair Gene Variants and Outcomes Among Patients
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  Authors: Meghan J. Price, Vishal Vashistha, David Winski, Michael J. Kelley, Rhonda L. Bitting, Bruce Montgomery
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-04-27T07:00:00
  DOI: 10.1200/PO.21.00461
Common Variant in ALDH2 Modifies the Risk of Breast Cancer Among Carriers
of the p.K3326* Variant in BRCA2
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  Authors: Wojciech Kluźniak, Agata Szymiczek, Amelie Rodrigue, Dominika Wokołorczyk, Bogna Rusak, Klaudia Stempa, Tomasz Huzarski, Jacek Gronwald, Jan Lubiński, Neda Zamani, Shiyu Zhang, Jean-Yves Masson, Steven A. Narod, Cezary Cybulski, Mohammad R. Akbari
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-04-20T07:00:00
  DOI: 10.1200/PO.21.00450
Acute Leukemia Classification Using Transcriptional Profiles From Low-Cost
Nanopore mRNA Sequencing
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  Authors: Jeremy Wang, Nickhill Bhakta, Vanessa Ayer Miller, Mahler Revsine, Mark R. Litzow, Elisabeth Paietta, Yuri Fedoriw, Kathryn G. Roberts, Zhaohui Gu, Charles G. Mullighan, Corbin D. Jones, Thomas B. Alexander
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Diagnostics
  Citation: JCO Precision Oncology
  PubDate: |2022-04-20T07:00:00
  DOI: 10.1200/PO.21.00326
Larotrectinib Before Initial Radioactive Iodine Therapy in Pediatric TRK
Fusion–Positive Papillary Thyroid Carcinoma: Time to Reconsider the
Treatment Paradigm for Distantly Metastatic Disease'
Open Access Article
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  Authors: Steven G. Waguespack, Sanjit O. Tewari, Naifa L. Busaidy, Mark E. Zafereo
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-04-14T07:00:00
  DOI: 10.1200/PO.21.00467
Circulating Tumor-Macrophage Fusion Cells and Circulating Tumor Cells
Complement Non–Small-Cell Lung Cancer Screening in Patients With
Suspicious Lung-RADS 4 Nodules
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  Authors: Yariswamy Manjunath, Kanve Nagaraj Suvilesh, Jonathan B. Mitchem, Diego M. Avella Patino, Eric T. Kimchi, Kevin F. Staveley-O'Carroll, Klaus Pantel, Huang Yi, Guangfu Li, Peter K. Harris, Aadel A. Chaudhuri, Jussuf T. Kaifi
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-04-13T07:00:00
  DOI: 10.1200/PO.21.00378
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-04-13T07:00:00
  DOI: 10.1200/PO.22.00175
Optimal Sequential Predictive Probability Designs for Early-Phase Oncology
Expansion Cohorts
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  Authors: Emily C. Zabor, Alexander M. Kaizer, Elizabeth Garrett-Mayer, Brian P. Hobbs
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Statistical Analysis
  Citation: JCO Precision Oncology
  PubDate: |2022-04-06T07:00:00
  DOI: 10.1200/PO.21.00390
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-04-06T07:00:00
  DOI: 10.1200/PO.22.00162
Diagnostic and Prognostic Implications of GNAS Inactivation in Sonic
Hedgehog–Activated Medulloblastoma: Case Report with Comprehensive
Molecular Profiling and Review of Literature
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  Authors: Erin Goode, Liliana Montoya, Eric Graham, Brianna Pruniski, Curtis Simmons, Alexander Ngwube, Lindsey M. Hoffman, Nishant Tiwari, Kenneth Aldape, Harper N. Price, Vera Paulson, Ross Mangum
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-31T07:00:00
  DOI: 10.1200/PO.21.00403
Hyperthermic Intraperitoneal Chemotherapy–Induced Molecular Changes in
Humans Validate Preclinical Data in Ovarian Cancer
Open Access Article
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  Authors: Thanh H. Dellinger, Ernest S. Han, Mustafa Raoof, Byrne Lee, Xiwei Wu, Hyejin Cho, Ting-Fang He, Peter Lee, Marianne Razavi, Winnie S. Liang, Daniel Schmolze, Saul J. Priceman, Stephen Lee, Wei-Chien Lin, Jeff F. Lin, Mehdi Kebria, Amy Hakim, Nora Ruel, Daphne B. Stewart, Edward W. Wang, Benjamin I. Paz, Mark T. Wakabayashi, Mihaela C. Cristea, Lorna Rodriguez-Rodriguez
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-03-31T07:00:00
  DOI: 10.1200/PO.21.00239
Perspectives and Experiences of Parents and Adolescents Who Participate in
a Pediatric Precision Oncology Program: "When You Feel Helpless, This Kind
of Thing Is Very Helpful"
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  Authors: Larissa Waldman, Kelly Hancock, Bailey Gallinger, Brittney Johnstone, Ledia Brunga, David Malkin, Maru Barrera, Anita Villani
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-31T07:00:00
  DOI: 10.1200/PO.21.00444
PIK3CA Mutations Drive Therapeutic Resistance in Human Epidermal Growth
Factor Receptor 2–Positive Breast Cancer
Open Access Article
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  Authors: Aryana R. Rasti, Amy Guimaraes-Young, Farrah Datko, Virginia F. Borges, Dara L. Aisner, Elena Shagisultanova
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-31T07:00:00
  DOI: 10.1200/PO.21.00370
Exploring Survival Outcomes in Metastatic Colorectal Cancer Harboring KRAS
A146 Mutations: Important Distinction or Simple Distraction'
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  Authors: Richard Pham, Azim Jalali, Chia Chong, Vanessa Wong, Kate Dunn, Peter Gibbs
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-28T07:00:00
  DOI: 10.1200/PO.21.00564
Reply to R. Pham et al
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  Authors: Iris van 't Erve, Cornelis J.A. Punt, Gerrit A. Meijer, Remond J.A. Fijneman
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-28T07:00:00
  DOI: 10.1200/PO.22.00053
Response to BRAF and MEK Inhibitors in BRAF Thr599dup–Mutated
Melanoma
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  Authors: Marion Oberlé, Philippe Jamme, Sandrine Mansard, Laurent Machet, Alice Hervieu, Nora Kramkimel, Anna Greliak, Anne Sophie Jarrousse, Valentin Derangère, David Dudoignon, Clotilde Descarpentries, Laurent Mortier
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-23T07:00:00
  DOI: 10.1200/PO.21.00417
Acquired Resistance Mechanisms to PD-L1 Blockade in a Patient With
Microsatellite Instability-High Extrahepatic Cholangiocarcinoma
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  Authors: Monica Niger, Federico Nichetti, Francesca Dell'Angelo, Vera Cappelletti, Chiara Pircher, Marta Vismara, Christian Cotsoglou, Sherrie Bhoori, Andrea Vingiani, Maria Di Bartolomeo, Filippo Pietrantonio, Filippo de Braud, Giancarlo Pruneri, Maria Grazia Daidone, Vincenzo Mazzaferro
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-23T07:00:00
  DOI: 10.1200/PO.21.00472
Landscape of KRASG12C, Associated Genomic Alterations, and Interrelation
With Immuno-Oncology Biomarkers in KRAS-Mutated Cancers
Open Access Article
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  Authors: Mohamed E. Salem, Sherif M. El-Refai, Wei Sha, Alberto Puccini, Axel Grothey, Thomas J. George, Jimmy J. Hwang, Bert O'Neil, Alexander S. Barrett, Kunal C. Kadakia, Laura W. Musselwhite, Derek Raghavan, Eric Van Cutsem, Josep Tabernero, Jeanne Tie
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-23T07:00:00
  DOI: 10.1200/PO.21.00245
Identifying Outcomes of Patients With Advanced Pancreatic Adenocarcinoma
and RECIST Stable Disease Using Radiomics Analysis
Open Access Article
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  Authors: Qiuxia Yang, Yize Mao, Hui Xie, Tao Qin, Zhijun Mai, Qian Cai, Hailin Wen, Yong Li, Rong Zhang, Lizhi Liu
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-23T07:00:00
  DOI: 10.1200/PO.21.00362
Changes in Triple-Negative Breast Cancer Molecular Subtypes in Patients
Without Pathologic Complete Response After Neoadjuvant Systemic
Chemotherapy
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  Authors: Hiroko Masuda, Kenichi Harano, Sakiko Miura, Ying Wang, Yuko Hirota, Oi Harada, Mohit Kumar Jolly, Yuki Matsunaga, Bora Lim, Anita L. Wood, Napa Parinyanitikul, Hee Jin Lee, Gyungyub Gong, Jason T. George, Herbert Levine, Jangsoon Lee, Xiaoping Wang, Anthony Lucci, Arvind Rao, Brock L. Schweitzer, O. Rayne Lawrence, Robert S. Seitz, Stephan W. Morris, David R. Hout, Seigo Nakamura, Savitri Krishnamurthy, Naoto T. Ueno
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-03-16T07:00:00
  DOI: 10.1200/PO.20.00368
Safety, Feasibility, and Merits of Longitudinal Molecular Testing of
Multiple Metastatic Sites to Inform mTNBC Patient Treatment in the
Intensive Trial of Omics in Cancer
Open Access Article
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  Authors: Kimberly A. Burton, Elisabeth Mahen, Eric Quentin Konnick, Sibel Blau, Michael O. Dorschner, Arturo B. Ramirez, Stephen C. Schmechel, Chaozhong Song, Rahul Parulkar, Stephanie Parker, Francis Mark Senecal, Colin C. Pritchard, Brigham H. Mecham, Christopher Szeto, Patricia Spilman, Jingchun Zhu, Vijayakrishna K. Gadi, Roy Ronen, Jackie Stilwell, Eric Kaldjian, Janusz Dutkowski, Stephen Charles Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, C. Anthony Blau
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-16T07:00:00
  DOI: 10.1200/PO.21.00280
FGFR Inhibitors in Cholangiocarcinoma: A Real-World Experience at a
Tertiary Center
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  Authors: Alessandro Rizzo, Giovanni Brandi
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-16T07:00:00
  DOI: 10.1200/PO.21.00511
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  Authors: Jennifer Gile, Amina Jatoi, Wen Wee Ma, Mitesh Borad, Nguyen H. Tran
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-16T07:00:00
  DOI: 10.1200/PO.22.00061
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-16T07:00:00
  DOI: 10.1200/PO.22.00116
Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in
Multinodular Hepatocellular Carcinoma
Open Access Article
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  Authors: Mairene Coto-Llerena, Andrej Benjak, John Gallon, Marie-Anne Meier, Tuyana Boldanova, Luigi M. Terracciano, Charlotte K.Y. Ng, Salvatore Piscuoglio
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-03-09T08:00:00
  DOI: 10.1200/PO.21.00335
Comparative Study of Bayesian Information Borrowing Methods in Oncology
Clinical Trials
Open Access Article
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  Authors: Liwen Su, Xin Chen, Jingyi Zhang, Fangrong Yan
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Statistical Analysis
  Citation: JCO Precision Oncology
  PubDate: |2022-03-09T08:00:00
  DOI: 10.1200/PO.21.00394
Impact of Circulating Tumor DNA–Based Detection of Molecular Residual
Disease on the Conduct and Design of Clinical Trials for Solid Tumors
Open Access Article
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  Authors: Pashtoon M. Kasi, Gordon Fehringer, Hiroya Taniguchi, Naureen Starling, Yoshiaki Nakamura, Daisuke Kotani, Thomas Powles, Bob T. Li, Lajos Pusztai, Vasily N. Aushev, Ekaterina Kalashnikova, Shruti Sharma, Meenakshi Malhotra, Zachary P. Demko, Alexey Aleshin, Angel Rodriguez, Paul R. Billings, Axel Grothey, Julien Taieb, David Cunningham, Takayuki Yoshino, Scott Kopetz
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-03-09T08:00:00
  DOI: 10.1200/PO.21.00181
Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers
Exhibiting Hypermutation: An IRRDC Study
Open Access Article
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  Authors: Jacob J. Henderson, Anirban Das, Daniel A. Morgenstern, Sumedha Sudhaman, Vanessa Bianchi, Jill Chung, Logine Negm, Melissa Edwards, David E. Kram, Michael Osborn, Cynthia Hawkins, Eric Bouffet, Yoon-Jae Cho, Uri Tabori
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-03-02T08:00:00
  DOI: 10.1200/PO.21.00286
Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in
Treatment-Naive Colorectal Cancer
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  Authors: Rodrigo Gularte-Mérida, Shaleigh Smith, Anita S. Bowman, Arnaud da Cruz Paula, Walid Chatila, Craig M. Bielski, Monika Vyas, Laetitia Borsu, Ahmet Zehir, Luciano G. Martelotto, Jinru Shia, Rona Yaeger, Fang Fang, Rui Gardner, Ruibang Luo, Michael C. Schatz, Ronglai Shen, Britta Weigelt, Francisco Sánchez-Vega, Jorge S. Reis-Filho, Jaclyn F. Hechtman
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-03-02T08:00:00
  DOI: 10.1200/PO.21.00365
Cyclin-Dependent Kinase 4/6 Inhibitor Outcomes in Patients With Advanced
Breast Cancer Carrying Germline Pathogenic Variants in DNA
Repair–Related Genes
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  Authors: Luisina Bruno, Alexis Ostinelli, Federico Waisberg, Diego Enrico, Carolina Ponce, Sergio Rivero, Albano Blanco, Martín Zarba, Martín Loza, Verónica Fabiano, Mora Amat, María Teresa Pombo, Laura Noro, Matías Chacón, Federico Coló, Reinaldo Chacón, Jorge Nadal, Adrián Nervo, Victoria Costanzo
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-03-02T08:00:00
  DOI: 10.1200/PO.21.00140
A Case of Prostate Cancer Harboring Androgen Receptor T878A
Progesterone-Responsive Mutant Emerging After Abiraterone Acetate
Treatment Responding to Darolutamide
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  Authors: Andreas Varkaris, Julia Stevens, Yuho Ono, Steven P. Balk, Joaquim Bellmunt
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-02-24T08:00:00
  DOI: 10.1200/PO.21.00091
Validity of 1% Hormonal Receptor Positivity Cutoff by the ASCO/College of
American Pathologists Guidelines at the Georgia Cancer Center
Open Access Article
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  Authors: Firas Kreidieh, Ramses F. Sadek, Li Fang Zhang, Aaron Gopal, Jean-Pierre Blaize, David Yashar, Reena Patel, Hiral S. Patel, Shou-Ching Tang, Houssein Abdul Sater
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-02-24T08:00:00
  DOI: 10.1200/PO.21.00201
PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for
Immunogenicity in BRCA-Deficient Ovarian Cancer
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  Authors: Adam A. Kraya, Kara N. Maxwell, Monika A. Eiva, Bradley Wubbenhorst, John Pluta, Michael Feldman, Anupma Nayak, Daniel J. Powell, Susan M. Domchek, Robert H. Vonderheide, Katherine L. Nathanson
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-02-24T08:00:00
  DOI: 10.1200/PO.21.00159
Clinical Opportunities for Germline Pharmacogenetics and Management of
Drug-Drug Interactions in Patients With Advanced Solid Cancers
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  Authors: Tyler Shugg, Reynold C. Ly, Elizabeth J. Rowe, Santosh Philips, Mustafa A. Hyder, Milan Radovich, Marc B. Rosenman, Victoria M. Pratt, John T. Callaghan, Zeruesenay Desta, Bryan P. Schneider, Todd C. Skaar
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-24T08:00:00
  DOI: 10.1200/PO.21.00312
Plasma Cell-Free DNA Integrity Assessed by Automated Electrophoresis
Predicts the Achievement of Pathologic Complete Response to Neoadjuvant
Chemotherapy in Patients With Breast Cancer
Open Access Article
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  Authors: Gabriella Cirmena, Lorenzo Ferrando, Francesco Ravera, Anna Garuti, Martina Dameri, Maurizio Gallo, Valentina Barbero, Fabio Ferrando, Lucia Del Mastro, Alessandro Garlaschi, Daniele Friedman, Piero Fregatti, Alberto Ballestrero, Gabriele Zoppoli
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-24T08:00:00
  DOI: 10.1200/PO.21.00198
Clinical Validity of Plasma-Based Genotyping for Microsatellite
Instability Assessment in Advanced GI Cancers: SCRUM-Japan GOZILA Substudy

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  Authors: Yoshiaki Nakamura, Wataru Okamoto, Tadamichi Denda, Tomohiro Nishina, Yoshito Komatsu, Satoshi Yuki, Hisateru Yasui, Taito Esaki, Yu Sunakawa, Makoto Ueno, Eiji Shinozaki, Nobuhisa Matsuhashi, Takashi Ohta, Ken Kato, Koushiro Ohtsubo, Hideaki Bando, Hiroki Hara, Taroh Satoh, Kentaro Yamazaki, Yoshiyuki Yamamoto, Naohiro Okano, Tetsuji Terazawa, Takeshi Kato, Eiji Oki, Akihito Tsuji, Yosuke Horita, Yasuo Hamamoto, Akihito Kawazoe, Hiromichi Nakajima, Shogo Nomura, Ryuta Mitani, Mihoko Yuasa, Kiwamu Akagi, Takayuki Yoshino
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-02-21T08:00:00
  DOI: 10.1200/PO.21.00383
Utility of Perioperative Measurement of Cell-Free DNA and Circulating
Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review
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  Authors: Phillip J. Hsu, Khushboo Singh, Ankit Dhiman, Hunter D. D. Witmer, Chuan He, Oliver S. Eng, Daniel V. T. Catenacci, Mitchell C. Posner, Kiran K. Turaga
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-21T08:00:00
  DOI: 10.1200/PO.21.00337
Real-World Experience of NTRK Fusion–Positive Thyroid Cancer
Open Access Article
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  Authors: Jong Chul Park, Arya Ashok, Chienying Liu, Hyunseok Kang
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-02-16T08:00:00
  DOI: 10.1200/PO.21.00442
Biomarker-Based Phase II Study of Sapanisertib (TAK-228): An mTORC1/2
Inhibitor in Patients With Refractory Metastatic Renal Cell Carcinoma
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  Authors: Bradley A. McGregor, Wanling Xie, Elio Adib, Walter M. Stadler, Yousef Zakharia, Aijai Alva, M. Dror Michaelson, Shilpa Gupta, Elaine T. Lam, Subrina Farah, Amin H. Nassar, Xiao X. Wei, Kerry L. Kilbridge, Lauren Harshman, Sabina Signoretti, Lynette Sholl, David J. Kwiatkowski, Rana R. McKay, Toni K. Choueiri
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-02-16T08:00:00
  DOI: 10.1200/PO.21.00448
Monitoring of Dynamic Changes and Clonal Evolution in Circulating Tumor
DNA From Patients With IDH-Mutated Cholangiocarcinoma Treated With
Isocitrate Dehydrogenase Inhibitors
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  Authors: Morten Lapin, Helen J. Huang, Sharmeen Chagani, Milind Javle, Rachna T. Shroff, Shubham Pant, Mohamed A. Gouda, Anjali Raina, Kiran Madwani, Veronica R. Holley, S. Greg Call, Derek J. Dustin, Richard B. Lanman, Funda Meric-Bernstam, Victoria M. Raymond, Lawrence N. Kwong, Filip Janku
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-02-16T08:00:00
  DOI: 10.1200/PO.21.00197
Identification of Recurrent Insertions and Deletions in Exon 18 and 19 of
Human Epidermal Growth Factor Receptor 2 as Potential Drivers in
Non–Small-Cell Lung Cancer and Other Cancer Types
Open Access Article
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  Authors: Yan Yin, Lijie Song, Dongsheng Shi, Bin Liu, Xiangke Li, Minjie Yang, Bihao Liu, Dejuan Wang, Jianwen Qin
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-16T08:00:00
  DOI: 10.1200/PO.21.00325
Lymphomatous Meningitis From Anaplastic Lymphoma Kinase+ Anaplastic Large
T-Cell Lymphoma Treated With Lorlatinib: A Case Report
Open Access Article
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  Authors: Smitha Mellacheruvu, Mark N. Sayegh, R. Alejandro Sica, Haiying Cheng, Maria Laureana Santos-Zabala, Jacob H. Gebrael, Ulrich Hermanto, Norman L. Rosen
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-02-09T08:00:00
  DOI: 10.1200/PO.21.00250
Phase Ib SEASTAR Study: Combining Rucaparib and Sacituzumab Govitecan in
Patients With Cancer With or Without Mutations in Homologous Recombination
Repair Genes
Open Access Article
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  Authors: Timothy A. Yap, Erika Hamilton, Todd Bauer, Ecaterina E. Dumbrava, Rinath Jeselsohn, Aaron Enke, Sabrina Hurley, Kevin K. Lin, Jenn Habeck, Heidi Giordano, Geoffrey I. Shapiro
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-02-09T08:00:00
  DOI: 10.1200/PO.21.00456
Phase II Study of Taselisib in PIK3CA-Mutated Solid Tumors Other Than
Breast and Squamous Lung Cancer: Results From the NCI-MATCH ECOG-ACRIN
Trial (EAY131) Subprotocol I
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  Authors: Ian E. Krop, Opeyemi A. Jegede, Juneko E. Grilley-Olson, Josh D. Lauring, Edith P. Mitchell, James A. Zwiebel, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Stanley R. Hamilton, Scott A. Kono, James M. Ford, Agustin A. Garcia, Xingwei D. Sui, Robert D. Siegel, Brian M. Slomovitz, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O'Dwyer, Alice P. Chen, Keith T. Flaherty
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-09T08:00:00
  DOI: 10.1200/PO.21.00424
Defining and Targeting Esophagogastric Cancer Genomic Subsets With
Patient-Derived Xenografts
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  Authors: Ryan H. Moy, Henry S. Walch, Marissa Mattar, Walid K. Chatila, Daniela Molena, Vivian E. Strong, Laura H. Tang, Steven B. Maron, Daniel G. Coit, David R. Jones, Jaclyn F. Hechtman, David B. Solit, Nikolaus Schultz, Elisa de Stanchina, Yelena Y. Janjigian
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-02-09T08:00:00
  DOI: 10.1200/PO.21.00242
Treatment of Disseminated Intravenous Leiomyomatosis With ALK Targeting
Crizotinib: A Successful Case Report
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  Authors: Priscila Barreto-Coelho, Andrew Rosenberg, Ty Subhawong, Philippos Costa, Andrea P. Espejo-Freire, Steven Bialick, Emily Jonczak, Jonathan C. Trent, Gina Z. D'Amato
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-02-02T08:00:00
  DOI: 10.1200/PO.21.00336
Clinical and Molecular Characterization of POLE Mutations as Predictive
Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers

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  Authors: Benjamin Garmezy, Jinesh Gheeya, Heather Y. Lin, Yuefan Huang, Taebeom Kim, Xianli Jiang, Kyaw Z. Thein, Patrick G. Pilié, Fadl Zeineddine, Wanlin Wang, Kenna R. Shaw, Jordi Rodon, John Paul Shen, Ying Yuan, Funda Meric-Bernstam, Ken Chen, Timothy A. Yap
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-02-02T08:00:00
  DOI: 10.1200/PO.21.00267
Distinct Genomic Landscapes in Early-Onset and Late-Onset Endometrial
Cancer
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  Authors: Jungyoon Choi, Andreana N. Holowatyj, Mengmeng Du, Zhishan Chen, Wanqing Wen, Nikolaus Schultz, Loren Lipworth, Xingyi Guo
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-02-02T08:00:00
  DOI: 10.1200/PO.21.00401
Clinical Utility of CDK4/6 Inhibitors in Sarcoma: Successes and Future
Challenges
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  Authors: Jocelyn Y. Hsu, Nathan D. Seligson, John L. Hays, Wayne O. Miles, James L. Chen
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-02-02T08:00:00
  DOI: 10.1200/PO.21.00211
Clinical Utility of Genomic Testing in Cancer Care
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  Authors: Daryl Pritchard, Clifford Goodman, Lincoln D. Nadauld
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.21.00349
Sustained Response to Entrectinib in an Infant With a Germline ALKAL2
Variant and Refractory Metastatic Neuroblastoma With Chromosomal 2p Gain

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  Authors: Diana Treis, Ganesh Umapathy, Susanne Fransson, Jikui Guan, Patricia Mendoza-García, Joachim T. Siaw, Sandra Wessman, Lena Gordon Murkes, Jakob J. E. Stenman, Anna Djos, Lotta H. M. Elfman, John Inge Johnsen, Bengt Hallberg, Ruth H. Palmer, Tommy Martinsson, Per Kogner
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.21.00271
Exceptional Response to Olaparib and Pembrolizumab for Pancreatic
Adenocarcinoma With Germline BRCA1 Mutation and High Tumor Mutation
Burden: Case Report and Literature Review
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  Authors: Joanne Lundy, Owen McKay, Daniel Croagh, Vinod Ganju
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.21.00437
Urinary 3-Methoxytyramine Is a Biomarker for MYC Activity in Patients With
Neuroblastoma
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  Authors: Iedan R. N. Verly, Yvette A. H. Matser, René Leen, Rutger Meinsma, Marta Fiocco, Jan Koster, Richard Volckmann, Dilara Savci-Heijink, Giuliana Cangemi, Sebastiano Barco, Linda J. Valentijn, Godelieve A. M. Tytgat, André B. P. van Kuilenburg
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.20.00447
Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA
Sequencing
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  Authors: Jayne Y. Hehir-Kwa, Marco J. Koudijs, Eugene T. P. Verwiel, Lennart A. Kester, Marc van Tuil, Eric Strengman, Arjan Buijs, Mariëtte E. G. Kranendonk, Laura S. Hiemcke-Jiwa, Valerie de Haas, Ellen van de Geer, Wendy de Leng, Jasper van der Lugt, Philip Lijnzaad, Frank C. P. Holstege, Patrick Kemmeren, Bastiaan B. J. Tops
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Diagnostics
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.20.00504
Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor
Kinase Fusion–Positive Lung Cancers
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  Authors: Alexander Drilon, Daniel S. W. Tan, Ulrik N. Lassen, Serge Leyvraz, Yongmei Liu, Jyoti D. Patel, Lee Rosen, Benjamin Solomon, Ricarda Norenberg, Laura Dima, Nicoletta Brega, Lin Shen, Victor Moreno, Shivaani Kummar, Jessica J. Lin
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-01-27T08:00:00
  DOI: 10.1200/PO.21.00418
Sustained Response to the Mitogen-Activated Extracellular Kinase Inhibitor
Trametinib in a Spindle Cell Sarcoma Harboring a QKI-RAF1 Gene Fusion
Open Access Article
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  Authors: François Panet, Sungmi Jung, Thierry Alcindor
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-20T08:00:00
  DOI: 10.1200/PO.21.00303
Apolipoprotein B mRNA-Editing Catalytic Polypeptide-Like–Induced Protein
Changes in Estrogen Receptor–Positive, Human Epidermal Growth Factor
Receptor 2–Negative Breast Cancer Throughout Disease Progression
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  Authors: Manouk K. Bos, Marcel Smid, Stefan Sleijfer, John W. M. Martens
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genomics
  Citation: JCO Precision Oncology
  PubDate: |2022-01-20T08:00:00
  DOI: 10.1200/PO.21.00190
ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to
Anti–Human Epidermal Growth Factor Receptor 2 Therapy in Advanced
Gastroesophageal Adenocarcinoma
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  Authors: Liangliang Zhang, Omar Hamdani, Ole Gjoerup, Cheryl Cho-Phan, Jeremy Snider, Emily Castellanos, Halla Nimeiri, Garrett Frampton, Jeffrey M. Venstrom, Geoffrey Oxnard, Samuel J. Klempner, Alexa B. Schrock
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-01-20T08:00:00
  DOI: 10.1200/PO.21.00330
Real-World Analysis of Off-Label Use of Molecularly Targeted Therapy in a
Large Academic Medical Center Cohort
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  Authors: Vivek A. Upadhyay, Bruce E. Johnson, Adam B. Landman, Michael J. Hassett
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Targeted Drug Therapy
  Citation: JCO Precision Oncology
  PubDate: |2022-01-20T08:00:00
  DOI: 10.1200/PO.21.00232
Tumor-Informed Versus Plasma-Only Liquid Biopsy Assay in a Patient With
Multiple Primary Malignancies
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  Authors: Pashtoon Murtaza Kasi
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-18T08:00:00
  DOI: 10.1200/PO.21.00298
Case of Metastatic Pheochromocytoma and Meningiomas in a Patient With
Lynch Syndrome
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  Authors: Meryl D. Colton, Kenneth Tompkins, Emily O'Donnell, Dara Aisner, Christopher H. Lieu, Eric Q. Konnick, Lauren Fishbein
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-13T08:00:00
  DOI: 10.1200/PO.21.00251
Circulating T-Cell Repertoires Correlate With the Tumor Response in
Patients With Breast Cancer Receiving Neoadjuvant Chemotherapy
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  Authors: Gengxi Cai, Zhanwen Guan, Yabin Jin, Zuhui Su, Xiangping Chen, Qing Liu, Chunlin Wang, Xiaoxia Yin, Lifang Zhang, Guolin Ye, Wei Luo
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-01-13T08:00:00
  DOI: 10.1200/PO.21.00120
Mainstreaming Genetic Testing for Epithelial Ovarian Cancer by Oncology
Providers: A Survey of Current Practice
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  Authors: Megan A. Czekalski, Rachelle C. Huziak, Andrea L. Durst, Sarah Taylor, Phuong L. Mai
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Cancer Genetics
  Citation: JCO Precision Oncology
  PubDate: |2022-01-13T08:00:00
  DOI: 10.1200/PO.21.00409
Mutant PPM1D- and TP53-Driven Hematopoiesis Populates the Hematopoietic
Compartment in Response to Peptide Receptor Radionuclide Therapy
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  Authors: Abhay Singh, Nuria Mencia-Trinchant, Elizabeth A. Griffiths, Alaa Altahan, Mahesh Swaminathan, Medhavi Gupta, Matthew Gravina, Rutaba Tajammal, Mark G. Faber, LunBiao Yan, Eti Sinha, Duane C. Hassane, David Neil Hayes, Monica L. Guzman, Renuka Iyer, Eunice S. Wang, Swapna Thota
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-01-13T08:00:00
  DOI: 10.1200/PO.21.00309
Erratum
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  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-13T08:00:00
  DOI: 10.1200/PO.21.00566
Real-World Data From a Molecular Tumor Board: Improved Outcomes in Breast
and Gynecologic Cancers Patients With Precision Medicine
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  Authors: Lindsey M. Charo, Ramez N. Eskander, Jason Sicklick, Ki Hwan Kim, Hyo Jeong Lim, Ryosuke Okamura, Suzanna Lee, Rupa Subramanian, Richard Schwab, Rebecca Shatsky, Steven Plaxe, Shumei Kato, Razelle Kurzrock
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-01-06T08:00:00
  DOI: 10.1200/PO.20.00508
Systematic Review of Molecular Biomarkers Predictive of Resistance to
CDK4/6 Inhibition in Metastatic Breast Cancer
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  Authors: Uzma S. Asghar, Ruhi Kanani, Rebecca Roylance, Sibylle Mittnacht
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Biomarkers
  Citation: JCO Precision Oncology
  PubDate: |2022-01-06T08:00:00
  DOI: 10.1200/PO.21.00002
Lasting Complete Clinical Response of a Recurring Cutaneous Squamous Cell
Carcinoma With MEK Mutation and PIK3CA Amplification Achieved by Dual
Trametinib and Metformin Therapy
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  Authors: Éva Remenár, Róbert Dóczi, Anna Dirner, Anna Sipos, Anita Perjési, Dóra Tihanyi, Barbara Vodicska, Dóra Lakatos, Katalin Horváth, Kornélia Kajáry, Richárd Schwáb, Júlia Déri, Csongor György Lengyel, Edit Várkondi, István Vályi-Nagy, István Peták
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-06T08:00:00
  DOI: 10.1200/PO.21.00344
Exceptional Clinical Response to Alectinib in Pancreatic Acinar Cell
Carcinoma With a Novel ALK-KANK4 Gene Fusion
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  Authors: Marina Gaule, Camilla Pesoni, Alberto Quinzii, Camilla Zecchetto, Simona Casalino, Valeria Merz, Serena Contarelli, Silvia Pietrobono, Elena Vissio, Luca Molinaro, Enrica Manzin, Roberta Volpatto, Giorgio Vellani, Davide Melisi
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Citation: JCO Precision Oncology
  PubDate: |2022-01-05T08:00:00
  DOI: 10.1200/PO.21.00400
Isocitrate Dehydrogenase–Mutated Cholangiocarcinoma: Natural History
and Clinical Outcomes
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  Authors: Grant Wintheiser, Tyler Zemla, Qian Shi, Nguyen Tran, Kritika Prasai, Sri Harsha Tella, Kabir Mody, Daniel Ahn, Mitesh Borad, Tanios Bekaii-Saab, Amit Mahipal
  Abstract: JCO Precision Oncology, Volume , Issue 6, April 2022.
  
  Keywords: Precision Medicine
  Citation: JCO Precision Oncology
  PubDate: |2022-01-05T08:00:00
  DOI: 10.1200/PO.21.00156