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Journal of Pediatric and Neonatal Individualized Medicine
Journal Prestige (SJR): 0.13
Number of Followers: 5  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2281-0692
Published by Hygeia Press Homepage  [1 journal]
  • Effect of human milk enriched with human milk-based fortifier (HMBF)
           versus bovine milk-based fortifier (BMBF) on growth and morbidity among
           very low birth weight (VLBW) infants – A randomized controlled trial

    • Authors: Rakesh Kotha, Kalyan Chakravarthy Konda, Paramesh Pandala, Alimelu Maddireddi
      Abstract: Introduction: Survival of preterm neonates increased dramatically with the advancement in neonatology services. These infants have high nutritional demands for optimal growth, and human milk alone is insufficient to meet their needs. Hence, fortification of milk has become the standard of care. Bovine milk-based fortifiers (BMBF) are commonly used, but there exists concern regarding the exposure to cow milk protein. Human milk-based fortifier (HMBF) use offers a theoretical advantage from the immunological and gastrointestinal standpoint. We intend to study the effects of HMBF compared to BMBF on growth and morbidity of preterm neonates. Methodology: It is a single-centre, open-labelled, randomized controlled trial (RCT) enrolling very low birth weight (VLBW) neonates of less than 34 weeks of gestation weighing between 1,000 and 1,500 g. Only human milk was used, and infants were randomized to receive either fortifier after reaching 100 ml/kg/day of enteral feeds. Growth and morbidity of preterm neonates were analysed. Results: A total of 50 infants were enrolled (25 in each arm). Weight gain (21.42 vs. 20.84 g/day, p = 0.77) and growth velocity (16.45 vs. 15.85 g/kg/day, p = 0.57) were similar in both groups with no statistical difference. Sepsis (relative risk [RR] = 0.6), feed intolerance (RR = 0.57), necrotizing enterocolitis (NEC) (RR = 0.33) and duration of hospital stay (33 vs. 36 days) were better in the HMBF group than in the BMBF group. Conclusion: Growth velocity was similar in both groups. However, HMBF was well tolerated by neonates with lesser incidence of feed intolerance, NEC, sepsis, and lesser hospital stay duration than in neonates supplemented with BMBF. Given the fewer number of studies, there is a need for well-powered RCTs with a good sample size to fill the knowledge gap.
      PubDate: 2021-11-17
      DOI: 10.7363/110104
      Issue No: Vol. 11, No. 1 (2021)
       
  • Lectures of the Nobel Week 2021 organized at Villa Nobel in Sanremo,
           Italy; Villa Nobel, Sanremo (Italy); December 11, 2021

    • Authors: --- Various Authors
      Abstract: Lectures of the Nobel Week 2021 organized at Villa Nobel in Sanremo, Italy   NEW FRONTIERS IN PEDIATRICS [NUOVE FRONTIERE IN PEDIATRIA]   Villa Nobel • Sanremo (Italy) • December 11th, 2021   The meeting has been organized by the Alfred Nobel’s Friends International Association and Centro Studi Alfred Nobel’s Friends Sanremo in collaboration with Prime Quality srl.   LECT 1. THE INTERNATIONAL ALFRED NOBEL’S FRIENDS STUDY CENTER IN SANREMO AND PEDIATRICS [IL CENTRO STUDI INTERNAZIONALE ALFRED NOBEL’S FRIENDS DI SANREMO E LA PEDIATRIA] • G. Trapani (Sanremo, Italy) LECT 2. LOW DOSE MEDICINE IN PEDIATRIC CLINICAL PRACTICE [LA LOW DOSE MEDICINE NELLA PRATICA CLINICA PEDIATRICA] • S. Bernasconi (Parma, Italy) LECT 3. HERBAL MEDICINE AND VIRUSES [FITOTERAPIA E VIRUS] • F. Macrì (Rome, Italy) LECT 4. NUTRACEUTICALS AND THE IMMUNE SYSTEM [NUTRACEUTICA E SISTEMA IMMUNITARIO] • G. Trapani (Sanremo, Italy) LECT 5. METABOLOMICS AND MICROBIOMICS: FROM PATHOLOGY TO VACCINATION [METABOLOMICA E MICROBIOMICA: DALLA PATOLOGIA ALLA VACCINAZIONE] • V. Fanos (Cagliari, Italy) LECT 6. THE NURSING MOTHER’S DIET: AN ADDED VALUE' [LA DIETA DELLA NUTRICE: UN VALORE AGGIUNTO'] • E. Bertino, S. Gandino (Turin, Italy) LECT 7. CHILDREN’S HEALTH AND ENVIRONMENT [LA SALUTE DEI BAMBINI E L’AMBIENTE] • E. Pira, C. Ciocan (Turin, Italy) LECT 8. THE ROLE OF BIFIDOBACTERIA IN THE HEALTH OF THE CHILD [IL RUOLO DEI BIFIDOBATTERI PER LA SALUTE DEL BAMBINO] • M. Romeo (Pavia, Italy) LECT 9. HAZELNUT SHELL CONTAINS A FUNCTIONAL FIBRE (AXOS) OF VALUE IN MODULATING THE METABOLIC RESPONSE IN HUMANS [DAGLI SCARTI DELLA NOCCIOLA, UN PREBIOTICO (AXOS) PER LA PREVENZIONE DELLE COMMUNICABLE DISEASES] • R. Menta (Alba, Italy)
      PubDate: 2021-11-16
      DOI: 10.7363/110101
      Issue No: Vol. 11, No. 1 (2021)
       
 
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