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Journal Cover International Scholarly Research Notices
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   ISSN (Online) 2356-7872
   Published by Hindawi Homepage  [269 journals]
  • Corrigendum to “Rheumatological Findings in Candidates for Valvular
           Heart Surgery”

    • PubDate: Mon, 27 Nov 2017 06:45:12 +000
       
  • Corrigendum to “Comparison between Fluconazole with Oral Protexin
           Combination and Fluconazole in the Treatment of Vulvovaginal
           Candidiasis”

    • PubDate: Mon, 27 Nov 2017 00:00:00 +000
       
  • Corrigendum to “The Severity of Retinopathy in the Extremely
           Premature Infants”

    • PubDate: Wed, 22 Nov 2017 00:00:00 +000
       
  • Corrigendum to “Does Comorbidity Increase the Risk of Dengue Hemorrhagic
           Fever and Dengue Shock Syndrome'”

    • PubDate: Wed, 22 Nov 2017 00:00:00 +000
       
  • Corrigendum to “Seroprevalence of Dengue IgG Antibodies among Healthy
           Adult Population in Lahore, Pakistan”

    • PubDate: Wed, 22 Nov 2017 00:00:00 +000
       
  • Sirolimus Ointment for Facial Angiofibromas in Individuals with Tuberous
           Sclerosis Complex

    • Abstract: Background. Facial angiofibromas affect most patients with tuberous sclerosis complex. They tend to progress, can cause recurrent bleeding and facial disfigurement, and have significant psychological effects. We reviewed the effectiveness and safety of topical sirolimus ointment 0.1%. We also assessed the effect of treatment on quality of life. Methods. We report our experience in using sirolimus ointment in 14 patients with TSC (9 children and 5 adults). The impact of sirolimus ointment was monitored with digital photography, dermatological review using a validated Facial Angiofibroma Severity Index (FASI), and quality of life assessments using the questionnaires PedsQL for children and SF36 for adults. Results. The FASI scores were improved in 12/14 cases after six months’ treatment, and improvement was more likely in children (median FASI scores of improvement after treatment were 3 points for children and 1 for adults). Proxy-reported PedsQL scores for the total psychosocial domain improved significantly in the children in the cohort with treatment. Conclusions. Sirolimus ointment 0.1% administered once a day was effective in treating facial angiofibromas. It appears to be safe and well tolerated and to have a positive impact on patients’ quality of life. It appeared to be most beneficial when started in childhood.
      PubDate: Wed, 15 Nov 2017 07:56:33 +000
       
  • Barriers to Diet and Exercise among Nepalese Type 2 Diabetic Patients

    • Abstract: This study aims to identify the modifiable barriers encountered by type 2 diabetic patients in Nepal to achieving their recommended dietary and exercise advice. A cross-sectional study was conducted among 197 type 2 diabetic patients, attending a diabetic clinic. Binary logistic regression models were used to identify perceived barriers. About 41% and 46% of the participants were noncompliant to diet and exercise advice, respectively; only 35.5% the participants were compliant to both. Perceived social acceptability (OR = 0.14; 95% CI: 0.03–0.58) and reminder to action (OR = 2.77; 95% CI: 1.38–5.53) were associated with noncompliance to diet. Most of the barriers to diet were related to taste, feast and festivals, lack of knowledge, and availability of healthy options. Self-efficacy (OR = 0.09; 95% CI: 0.02–0.34) and social acceptability (OR = 0.12; 95% CI: 0.04–0.34) were significant predictors of noncompliance to exercise. The supportive role of children and spouse and the opposing role of friends and relatives were important for compliance to both. A misconception on diabetes severity, effectiveness of healthy lifestyle, and exercise timing was prevalent among the study participants. Addressing the modifiable barriers identified in this study is essential for successful diabetes management in Nepal.
      PubDate: Tue, 14 Nov 2017 00:00:00 +000
       
  • The In Vivo Dynamics of HIV Infection with the Influence of Cytotoxic T
           Lymphocyte Cells

    • Abstract: The in vivo dynamics of HIV infection, the infection mechanism, the cell types infected, and the role played by the cytotoxic cells are poorly understood. This paper uses mathematical modelling as a tool to investigate and analyze the immune system dynamics in the presence of HIV infection. We formulate a six-dimensional model of nonlinear ordinary differential equations derived from known biological interaction mechanisms between the immune cells and the HIV virions. The existence and uniqueness as well as positivity and boundedness of the solutions to the differential equations are proved. Furthermore, the disease-free reproduction number is derived and the local asymptotic stability of the model investigated. In addition, numerical analysis is carried out to illustrate the importance of having . Lastly, the biological dynamics of HIV in vivo infection are graphically represented. The results indicate that, at acute infection, the cytotoxic T-cells play a paramount role in reducing HIV viral replication. In addition, the results emphasize the importance of developing controls, interventions, and management policies that when implemented would lead to viral suppression during acute infection.
      PubDate: Tue, 14 Nov 2017 00:00:00 +000
       
  • Corrigendum to “On a Nonlinear Wave Equation Associated with Dirichlet
           Conditions: Solvability and Asymptotic Expansion of Solutions in Many
           Small Parameters”

    • PubDate: Sun, 05 Nov 2017 00:00:00 +000
       
  • The Severity of Retinopathy in the Extremely Premature Infants

    • Abstract: Objective. We aimed to investigate the incidence and the severity of retinopathy of extremely premature infants and to evaluate the risk factors and outcome of the cases. Materials and Methods. Out of 200 premature births, we retrospectively reviewed 9 cases that developed ROP. We excluded cases where ROP developed in newborns > 30 weeks of gestational age and cases where medical notes were unavailable or incomplete. Topical drops of cyclopentolate 1% and phenylephrine 5% were instilled and fundoscopy was performed using a direct ophthalmoscope. Results. The incidence of ROP was 4.5% in the 9-year period. The infants were divided into two groups. Group 1 included premature infants ≤27 weeks of age and Group 2 included those >27 weeks but ≤ 30 weeks of age. We found that the infants of Group 1 showed advanced stages of ROP in comparison to Group 2. Out of 18 eyes, 11 eyes had stage 3 ROP and they were all found in Group 1 (100% of cases). Conclusion. The severity of ROP was associated with earlier gestational age, lower birth weight, and oxygen supplementation. Constant cooperation between physicians and nursing staff is necessary to avoid undetected cases and further prevent ROP related blindness.
      PubDate: Wed, 18 Oct 2017 00:00:00 +000
       
  • Corrigendum to “Utilization of Preventive Measures for
           Glucocorticoid-Induced Osteoporosis among Veterans with Inflammatory Bowel
           Disease”

    • PubDate: Mon, 18 Sep 2017 00:00:00 +000
       
  • Study on Strength Behavior of Organic Soil Stabilized with Fly Ash

    • Abstract: The aim of this study is to investigate the effect of fly ash on the consistency, compactness, acidic properties, and strength of organic soil. The presence of organic content in the soil has detrimental impacts on the physical and strength behavior of soil. To investigate the effectiveness of fly ash in the stabilization of organic soil, two types of fly ashes (Type I and Type II) at different percentages were used. It is found that fly ash significantly reduces the plasticity index of the organic soil, whereas the liquid and plastic limits increase. The dry density of the fly ash-soil mixture increases significantly, while the water requirement reduces due to the addition of fly ash. The increase of dry density compromises higher strength. The increase of with the increase of fly ash content is mainly due to the pozzolanic reaction of fly ash, although the reduction in water content results from the addition of dry fly ash solid. Moreover, Type I fly ash contributes a higher value of qu compared to Type II fly ash. This is attributed to the characteristics of fly ash including CaO and CaO/SiO2 ratio.
      PubDate: Mon, 11 Sep 2017 09:47:16 +000
       
  • Physicochemical Characterization and Polyphenolic Content of Beninese
           Honeys

    • Abstract: The physicochemical and phytochemical analyses of honeys () from Sudanese, Sudano-Guinean, and Guinean areas of Benin were investigated. Results showed that dark amber is the dominant color. Moisture content ranged from 15.50% to 23.50%, and 72% of honeys respected the Codex Alimentarius recommendation. pH varied between 2.87 and 6.15, and free acidity ranged from 9.00 to 39.00 meq/kg. Electrical conductivity varied from 0.37 to 1.43 mS/cm. The content in fructose varied from 21.67% to 94.21%, and proline content ranged between 306.31 and 1187.93 mg/kg. All physicochemical characteristics varied with the areas. A negative correlation was found between pH and moisture content (; ). A positive correlation was established between pH and conductivity (; ) and between proline and color (; ). Total phenolic content varied between 55.97 and 224.99 mg GAE/100 g, and flavonoid content ranged between 1.43 and 29.81 mg CAE/100 g. Flavonoid was positively correlated with color (; ) and proline (; ). Tukey’s test revealed differences between total phenolic and flavonoid contents of honeys from five areas (). In general, Sudanese and Sudano-Guinean honeys showed potential toward therapeutic applications because of their high phenolic contents.
      PubDate: Thu, 07 Sep 2017 10:03:26 +000
       
  • Contraceptive Methods Accessed in Volta Region, Ghana, 2009–2014

    • Abstract: Introduction. In 2016, Volta Region was one of the two regions in Ghana that recorded a high prevalence of teenage pregnancy, accounting for 15.5% of all adolescent pregnancies in the country. This study aimed to determine the prevalence of contraceptive methods accessed by person, place, and time in Volta Region, Ghana, 2009–2014. Method. We carried out a secondary analysis of contraceptive use data derived from the District Health Information Management System (DHIMS) 2 for Volta Region, between 2009 and 2014. We calculated proportions and described trends. Results. Over the five-year period, there were 673,409 (75.0%) acceptors of family planning out of a total 897, 645 males and females of reproductive age. The proportion of family planning acceptors increased gradually from 18% in 2009 to 23% in 2014. Contraceptive methods were most commonly accessed by male and female between 20 and 29 years. The most common methods of contraceptives accessed were injectables among females accounting for about 70% and condoms accounting for over 90% among males. Conclusion. All the districts in Volta Region did not access contraceptives adequately. The Volta Regional Health Directorate should encourage and support research to ascertain factors influencing uptake of contraceptive methods in all the districts.
      PubDate: Thu, 07 Sep 2017 08:15:31 +000
       
  • Diversity of Aerobic Bacteria Isolated from Oral and Cloacal Cavities from
           Free-Living Snakes Species in Costa Rica Rainforest

    • Abstract: Costa Rica has a significant number of snakebites per year and bacterial infections are often complications in these animal bites. Hereby, this study aims to identify, characterize, and report the diversity of the bacterial community in the oral and cloacal cavities of venomous and nonvenomous snakes found in wildlife in Costa Rica. The snakes where captured by casual encounter search between August and November of 2014 in the Quebrada González sector, in Braulio Carrillo National Park. A total of 120 swabs, oral and cloacal, were taken from 16 individuals of the Viperidae and Colubridae families. Samples were cultured on four different media at room temperature. Once isolated in pure culture, colonies were identified with the VITEK® 2C platform (bioMérieux). In order to test the identification provided on environmental isolates, molecular analyses were conducted on 27 isolates of different bacterial species. Specific 16S rDNA PCR-mediated amplification for bacterial taxonomy was performed, then sequenced, and compared with sequences of Ribosomal Database Project (RDP). From 90 bacterial isolates, 40 different bacterial species were identified from both oral and cloacal swabs. These results indicate the diversity of opportunistic pathogens present and their potential to generate infections and zoonosis in humans.
      PubDate: Sun, 20 Aug 2017 09:17:36 +000
       
  • Accuracy of Preoperative Scoring Systems for the Prognostication and
           Treatment of Patients with Spinal Metastases

    • Abstract: Background. In patients with spinal metastatic disease, survival prognosis is a key consideration in selection for surgery and determining the extent of treatment. Individual survival prediction however remains difficult. We sought to validate the prognostic accuracy of seven preoperative scoring systems. Methods. 61 patients surgically treated for spinal metastases were retrospectively reviewed. Preoperative scores were calculated for Tokuhashi, Revised Tokuhashi, Bauer, Modified Bauer, Sioutos, Tomita, and van der Linden scoring systems. Prognostic value was determined by comparison of predicted and actual survival. Results. The Revised Tokuhashi and Modified Bauer scoring systems had the best survival predictive accuracy. Rate of agreement for survival prognosis was the greatest for the Modified Bauer score. There was a significant difference in survival of the prognostic groups for all but the van der Linden score, being most significant for the Revised Tokuhashi, Bauer, Modified Bauer, and Tomita scoring systems (). Conclusion. Overall, the scoring systems are accurate at differentiating patients into short-, intermediate-, and long-term survivors. More precise prediction of actual survival is limited and the decision for or against surgery should never be based on survival prognostication alone but should take into account symptoms such as neurological deficit or pain from pathological fracture and instability.
      PubDate: Tue, 15 Aug 2017 09:10:10 +000
       
  • Use of Genotype MTBDRplus Assay for Diagnosis of Multidrug-Resistant
           Tuberculosis in Nepal

    • Abstract: The main aims of this study were to study the patterns of mutations in rpoB, katG, and inhA genes in Mycobacterium tuberculosis strains isolated from patients from Nepal and to evaluate the performance of genotype MTBDRplus assay, taking conventional drug susceptibility testing as gold standard for diagnosis of MDR-TB. A total of 69 Mycobacterium tuberculosis strains isolated from 73 smear positive sputum samples from patients suspected of suffering from multidrug-resistant tuberculosis were used in our study. The drug susceptibility pattern of Mycobacterium tuberculosis isolated from these sputum specimens was determined by using genotype MTBDRplus assay taking conventional drug susceptibility testing as reference. The sensitivity and specificity of the genotype MTBDRplus assay for the detection of MDR-TB were found to be 88.7% and 100%, respectively. 88.7% of the rifampicin resistant isolates had mutations in rpoB gene. Similarly, 79.7% and 9.4% of isoniazid resistant isolates had mutations in katG and inhA genes, respectively. Genotype MTBDRplus assay was found to be very rapid and highly sensitive and specific method for diagnosis of MDR-TB and will be very helpful for early diagnosis of MDR-TB in high tuberculosis burden countries.
      PubDate: Sun, 13 Aug 2017 00:00:00 +000
       
  • Fortification of Ogi with Whey Increases Essential Amino Acids Content of
           Fortified Product

    • Abstract: The inability of humans to synthesize essential amino acids (EAA) necessitates the need to increase the levels of these nutrient molecules in certain foods in which they are deficient. Maize ogi is a typical food product for both infants and adults in Africa, but with poor EAA content. This study therefore sought to assess the possibility of increasing the EAA content in maize ogi by processing it with cheese whey instead of water. Maize ogi and whey-fortified ogi were prepared by the usual procedure of grain soaking, milling, and drying. Samples from both treatments were subjected to proximate composition and amino acid profile analyses using Waters 616/626 LC (HPLC) instrument. L-lysine, L-trytophan, and L-methionine contents in maize ogi remarkably increased from 0.52, 0.15, and 0.90 mg/100 gm sample, respectively, to 0.90, 240, and 1.320 mg/100 gm sample in whey-fortified ogi. There were also significant increases in other EAA contents of whey-fortified ogi relative to its counterpart (normal maize ogi). The sum increase in EAA contents (9,405 mg) correlates with the increase in protein (1 gm) per gram sample. This study demonstrates that cheese whey increases EAA content in maize ogi and suggests that whey-fortified maize ogi may be a preferred alternative to water processed maize ogi.
      PubDate: Mon, 07 Aug 2017 00:00:00 +000
       
  • Use of the Bayley Scales of Infant and Toddler Development, Third Edition,
           to Assess Developmental Outcome in Infants and Young Children in an Urban
           Setting in South Africa

    • Abstract: Background. The Bayley Scales of Infant and Toddler Development (III) is a tool developed in a Western setting. Aim. To evaluate the development of a group of inner city children in South Africa with no neonatal risk factors using the Bayley Scales of Infant and Toddler Development (III), to determine an appropriate cut-off to define developmental delay, and to establish variation in scores done in the same children before and after one year of age. Methods. Cohort follow-up study. Results. 74 children had at least one Bayley III assessment at a mean age of 19.4 months (95% CI 18.4 to 20.4). The mean composite cognitive score was 92.2 (95% CI 89.4 to 95.0), the mean composite language score was 94.8 (95% CI 92.5 to 97.1), and mean composite motor score was 98.8 (95% CI 96.8 to 101.0). No child had developmental delay using a cut-off score of 70. In paired assessments above and below one year of age, the cognitive score remained unchanged, the language score decreased significantly (), and motor score increased significantly () between the two ages. Conclusion. The Bayley Scales of Infant and Toddler Development (III) is a suitable tool for assessing development in urban children in southern Africa.
      PubDate: Tue, 01 Aug 2017 07:56:25 +000
       
  • Modeling the Impact of Bed-Net Use and Treatment on Malaria Transmission
           Dynamics

    • Abstract: We modeled the impact of bed-net use and insecticide treated nets (ITNs), temperature, and treatment on malaria transmission dynamics using ordinary differential equations. To achieve this we formulated a simple model of mosquito biting rate that depends on temperature and usage of insecticides treated bed nets. We conducted global uncertainty and sensitivity analysis using Latin Hypercube Sampling (LHC) and Partial Rank Correlation Coefficient (PRCC) in order to find the most effective parameters that affect malaria transmission dynamics. We established the existence of the region where the model is epidemiologically feasible. We conducted the stability analysis of the disease-free equilibrium by the threshold parameter. We found the condition for the existence of the endemic equilibrium and provided necessary condition for its stability. Our results show that the peak of mosquitoes biting rate occurs at a range of temperature values not on a single value as previously reported in literature. The results also show that the combination of treatment and ITNs usage is the most effective intervention strategy towards control and eradication of malaria transmissions. Sensitivity analysis results indicate that the biting rate and the mosquitoes death rates are the most important parameters in the dynamics of malaria transmission.
      PubDate: Tue, 01 Aug 2017 00:00:00 +000
       
  • Clinician’s Update on the Benign, Premalignant, and Malignant Skin
           Tumours of the Vulva: The Dermatologist’s View

    • Abstract: Correct and rapid diagnosis of skin tumours often requires biopsy and histopathological examination to differentiate benign lesions such as seborrhoeic keratoses or melanocytic naevi from premalignant and malignant lesions such as malignant melanoma. Particularly, to the untrained eye, any benign skin tumour—pigmented or nonpigmented—is easily mistaken for a malignant lesion. Qualified clinical evaluation is paramount in order to reduce the frequency of unwarranted skin biopsies. Herein, the most common benign, premalignant, and malignant vulvar skin tumours are reviewed.
      PubDate: Tue, 25 Jul 2017 07:55:59 +000
       
  • Acute Appendicitis in Pregnancy and the Developing World

    • Abstract: Background. Acute appendicitis is the commonest nonobstetric surgical emergency during pregnancy. The aim of the study was to compare perioperative outcomes of acute appendicitis in pregnant and nonpregnant patients. Methods. A retrospective review of medical records of 56 pregnant patients between 2011 and 2016 who were compared with 164 nonpregnant women of reproductive age who underwent open appendectomy between 2014 and 2016 for acute appendicitis. The patient’s demographics and perioperative data were analyzed. Results. The median age of pregnant and nonpregnant patients observed was 26 years (range 19–37) and 26 years (range 18–43). There were no significant differences between the groups in negative appendectomy (21.4 and 21.3%, ), perforated appendicitis (25 and 23.8%, ), postoperative complications (28.6 and 26.8%, ), and median length of hospital stay (5 and 4.5 days, ). There were 3.6% preterm labour, no maternal mortality, and no fetal loss. In multivariate analysis, WBC >18000/mm3 and long patient time to surgery were independent risk factors for appendicular perforation and postoperative complication (). Conclusion. Our results of appendectomy in pregnant patients are comparable with nonpregnant patients. Hence the same perioperative treatment protocol can be followed in pregnant and nonpregnant patients even in resource-poor setting.
      PubDate: Thu, 20 Jul 2017 00:00:00 +000
       
  • The Ethanolic Stem-Bark Extract of Antrocaryon micraster Inhibits
           Carrageenan-Induced Pleurisy and Pedal Oedema in Murine Models of
           Inflammation

    • Abstract: We investigated the antioxidant and anti-inflammatory effects of a 70% v/v ethanol extract of the stem bark of Antrocaryon micraster on murine models of carrageenan-induced pleurisy and paw oedema. Rat pleural fluid was analysed for volume, protein content, and leucocytes, while lung histology was assessed for damage. Lung tissue homogenates were assayed for glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), and myeloperoxidase (MPO). Phytochemical analysis was carried out on the stem bark. Acute toxicity studies were conducted in rats. In the pleurisy model the extract (30–300 mg/kg) significantly reduced the volume and amount of proteins and leucocytes in the exudate and also protected against lung injury. Tissue level of GSH and SOD and CAT expression were increased while MDA level and MPO activity were reduced. The peak and total oedema responses were significantly suppressed when given both preemptively and curatively in the mice paw oedema test. Saponins, alkaloids, triterpenoids, and tannins were present in the stem bark. A. micraster extract exhibited no apparent acute toxicity. We conclude that the ethanolic stem-bark extract of A. micraster has antioxidant action and exhibits significant anti-inflammatory activity through suppression of pleurisy and paw oedema induced with carrageenan.
      PubDate: Mon, 17 Jul 2017 08:01:55 +000
       
  • Corrigendum to “Risk Factors for Fracture in Diabetes: The Canadian
           Multicentre Osteoporosis Study”

    • PubDate: Wed, 12 Jul 2017 07:40:33 +000
       
  • Review of Organism Density and Bacteriologic Conversion of Sputum among
           Tuberculosis Patients

    • Abstract: Objective. This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. Methods. We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage. Results. A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (), scanty (), ++ (), and +++ (). We recorded sputum conversion rate of 80.90%, 94.56%, and 98.31% in the intensive, continuation, and completion phases, respectively. Conclusion. This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment.
      PubDate: Tue, 11 Jul 2017 00:00:00 +000
       
  • Corrigendum to “Recommendations for Diagnosis and Management of
           Osteoporosis in COPD Men”

    • PubDate: Sun, 02 Jul 2017 08:14:41 +000
       
  • Dual Kidney Transplantation: A Review of Past and Prospect for Future

    • Abstract: Kidney transplantation (KT) is one of the treatment options for patients with chronic kidney disease. The number of patients waiting for kidney transplantation is growing day by day. Various strategies have been put in place to expand the donor pool. Extended criteria donors are now accepted more frequently. Increasing number of elderly donors with age > 60 years, history of diabetes or hypertension, and clinical proteinuria are accepted as donor. Dual kidney transplantation (DKT) is also more frequently done and experience with this technique is slowly building up. DKT not only helps to reduce the number of patients on waiting list but also limits unnecessary discard of viable organs. Surgical complications of DKT are comparable to single kidney transplantation (SKT). Patient and graft survivals are also promising. This review article provides a summary of evidence available in the literature.
      PubDate: Sun, 02 Jul 2017 07:44:45 +000
       
  • Retracted: Physical Activity: An Important Adaptative Mechanism for
           Body-Weight Control

    • PubDate: Sun, 02 Jul 2017 06:46:45 +000
       
  • Corrigendum to “Risk Factors for Falls and Fragility Fractures in
           Community-Dwelling Seniors: A One-Year Prospective Study”

    • PubDate: Sun, 02 Jul 2017 06:23:37 +000
       
  • S-100β and Antioxidant Capacity in Cerebrospinal Fluid during and after
           Thoracic Endovascular Aortic Repair

    • Abstract: Background. Thoracic Endovascular Aortic Repair (TEVAR) has substantially decreased the mortality and major complications from aortic surgery. However, neurological complications such as spinal cord ischemia may still occur after TEVAR. S-100β is a biomarker of central nervous system injury, and oxidant injury plays an important role in neurological injury. In this pilot study, we examined the trends of S-100β and antioxidant capacity in the CSF during and after TEVAR. Methods. We recruited 10 patients who underwent elective TEVAR. CSF samples were collected through a lumbar catheter at the following time points: before the start of surgery () and immediately () and 24 () and 48 hours () after the deployment of the aortic stent. S-100β and CSF antioxidant capacity were analyzed with the use of commercially available kits. Results. We observed that the level of S-100β in all of the subjects at 24 hours after the deployment of the aortic stent () increased. However, the levels of S-100β at and were comparable to the baseline value. The antioxidant capacity remained unchanged. No patient had a clinical neurologic complication. Conclusions. Our observations may indicate biochemical/subclinical central nervous system injury attributable to the deployment of the aortic stent.
      PubDate: Tue, 27 Jun 2017 07:09:06 +000
       
 
 
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