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Journal Cover Nature Communications
  Journal Prestige (SJR): 6.539
  Citation Impact (citeScore): 114
  Number of Followers: 220  
    
  This is an Open Access Journal Open Access journal
   ISSN (Online) 2041-1723
   Published by NPG Homepage  [143 journals]
  • FGF signalling controls the specification of hair placode-derived SOX9
           positive progenitors to Merkel cells
    • FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells

      FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells, Published online: 20 June 2018; doi:10.1038/s41467-018-04399-y

      Merkel cells are mechanoreceptors located in the epidermis whose developmental origin is unclear. Here the authors show that Merkel cells originate from SOX9 positive cells inside hair follicles and that FGFR2-mediated epithelial signalling is required for their specification.FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells, Published online: 2018-06-20; doi:10.1038/s41467-018-04399-y2018-06-20
      DOI: 10.1038/s41467-018-04399-y
       
  • Carbon nitride supported Fe2 cluster catalysts with superior performance
           for alkene epoxidation
    • Carbon nitride supported Fe2 cluster catalysts with superior performance for alkene epoxidation

      Carbon nitride supported Fe2 cluster catalysts with superior performance for alkene epoxidation, Published online: 15 June 2018; doi:10.1038/s41467-018-04845-x

      Sub-nano clusters with atomic precision provide a compelling platform for bridging heterogeneous and homogeneous catalysis, but their synthesis remains a great challenge. Here, the authors report a precursor-preselected wet-chemistry strategy to synthesize highly dispersed Fe2 clusters supported on mesoporous carbon nitride.Carbon nitride supported Fe2 cluster catalysts with superior performance for alkene epoxidation, Published online: 2018-06-15; doi:10.1038/s41467-018-04845-x2018-06-15
      DOI: 10.1038/s41467-018-04845-x
       
  • Liquid phase blending of metal-organic frameworks
    • Liquid phase blending of metal-organic frameworks

      Liquid phase blending of metal-organic frameworks, Published online: 15 June 2018; doi:10.1038/s41467-018-04553-6

      The recently introduced glass and liquid states of metal–organic frameworks (MOFs) provide opportunities to design and explore new properties for this class of material. Here, the authors show that a MOF liquid can be blended with another MOF component to produce domain-structured MOF glasses with single, tailorable glass transitions.Liquid phase blending of metal-organic frameworks, Published online: 2018-06-15; doi:10.1038/s41467-018-04553-62018-06-15
      DOI: 10.1038/s41467-018-04553-6
       
  • Efficient RNA drug delivery using red blood cell extracellular vesicles
    • Efficient RNA drug delivery using red blood cell extracellular vesicles

      Efficient RNA drug delivery using red blood cell extracellular vesicles, Published online: 15 June 2018; doi:10.1038/s41467-018-04791-8

      RNA delivery for disease treatment often has low uptake efficiencies and cytotoxicity. Here the authors produce extracellular vesicles from red blood cells for in vivo cargo delivery.Efficient RNA drug delivery using red blood cell extracellular vesicles, Published online: 2018-06-15; doi:10.1038/s41467-018-04791-82018-06-15
      DOI: 10.1038/s41467-018-04791-8
       
  • Strong lowering of ionization energy of metallic clusters by organic
           ligands without changing shell filling
    • Strong lowering of ionization energy of metallic clusters by organic ligands without changing shell filling

      Strong lowering of ionization energy of metallic clusters by organic ligands without changing shell filling, Published online: 15 June 2018; doi:10.1038/s41467-018-04799-0

      Metallic clusters with an excess electron beyond a closed shell have very low ionization energies, in analogy to alkali atoms. Here, the authors use select ligands to lower the ionization energy of metallic clusters without changing the number of valence electrons, introducing a route to alkali-like superatoms that is independent of the final shell occupancy.Strong lowering of ionization energy of metallic clusters by organic ligands without changing shell filling, Published online: 2018-06-15; doi:10.1038/s41467-018-04799-02018-06-15
      DOI: 10.1038/s41467-018-04799-0
       
  • When optimization for governing human-environment tipping elements is
           neither sustainable nor safe
    • When optimization for governing human-environment tipping elements is neither sustainable nor safe

      When optimization for governing human-environment tipping elements is neither sustainable nor safe, Published online: 15 June 2018; doi:10.1038/s41467-018-04738-z

      Economic optimization in environmental governance was criticized for delivering short-term gains at the expense of long-term environmental degradation. Here, the authors use a stylized model of human-environment tipping elements to show no paradigm guarantees fulfilling another paradigm.When optimization for governing human-environment tipping elements is neither sustainable nor safe, Published online: 2018-06-15; doi:10.1038/s41467-018-04738-z2018-06-15
      DOI: 10.1038/s41467-018-04738-z
       
  • Dual-functional peptide with defective interfering genes effectively
           protects mice against avian and seasonal influenza
    • Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza

      Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza, Published online: 15 June 2018; doi:10.1038/s41467-018-04792-7

      A limited number of therapeutics is available to treat influenza A virus (IAV) infections. Here, the authors show that defective interfering genes, delivered with a dual-functional peptide that enables intracellular accumulation and prevents endosomal acidification, inhibit IAV replication in vitro and in vivo.Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza, Published online: 2018-06-15; doi:10.1038/s41467-018-04792-72018-06-15
      DOI: 10.1038/s41467-018-04792-7
       
  • Nanoscale metal-organic frameworks enhance radiotherapy to potentiate
           checkpoint blockade immunotherapy
    • Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

      Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy, Published online: 15 June 2018; doi:10.1038/s41467-018-04703-w

      Radiotherapy is known to have local immunomodulatory effects, while an effective systemic immune response is an issue. Here, the authors report on nMOF radiosensitizers for enhanced radiotherapy which in combination with anti-PD-L1 antibodies result in a systemic immune response to distant tumors.Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy, Published online: 2018-06-15; doi:10.1038/s41467-018-04703-w2018-06-15
      DOI: 10.1038/s41467-018-04703-w
       
 
 
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