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Journal Cover Nature Reviews Immunology
  [SJR: 26.85]   [H-I: 292]   [210 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1474-1733 - ISSN (Online) 1474-1741
   Published by NPG Homepage  [136 journals]
  • Chemokines: Moving on up
    • Chemokines: Moving on up

      Chemokines: Moving on up, Published online: 04 December 2017; doi:10.1038/nri.2017.137

      Chemotaxis of myeloid cells in response to CCL19 and CXCL12 involves temporal sensing of an increasing source concentration of chemokine.Chemokines: Moving on up, Published online: 2017-12-04; doi:10.1038/nri.2017.1372017-12-04
      DOI: 10.1038/nri.2017.137
       
  • Vaccines in 2017: Closing in on a Zika virus vaccine
    • Vaccines in 2017: Closing in on a Zika virus vaccine

      Vaccines in 2017: Closing in on a Zika virus vaccine, Published online: 04 December 2017; doi:10.1038/nri.2017.132

      Over the past 2 years, Zika virus (ZIKV) has emerged as a pathogen capable of causing devastating congenital malformations in the developing fetus and significant neurological disease in adults. In 2017, substantial progress has been made towards the development, immunological analysis and preclinical evaluation of vaccine platforms to prevent the pathologies associated with ZIKV infection.Vaccines in 2017: Closing in on a Zika virus vaccine, Published online: 2017-12-04; doi:10.1038/nri.2017.1322017-12-04
      DOI: 10.1038/nri.2017.132
       
  • ITIMs: episode 1 of the inhibitory saga
    • ITIMs: episode 1 of the inhibitory saga

      ITIMs: episode 1 of the inhibitory saga, Published online: 27 November 2017; doi:10.1038/nri.2017.134

      Eric Vivier recounts how the initial description of the ITIM motif in FcγRIIB helped to launch the field of inhibitory immune receptors.ITIMs: episode 1 of the inhibitory saga, Published online: 2017-11-27; doi:10.1038/nri.2017.1342017-11-27
      DOI: 10.1038/nri.2017.134
       
  • Microglia and macrophages in brain homeostasis and disease
    • Microglia and macrophages in brain homeostasis and disease

      Microglia and macrophages in brain homeostasis and disease, Published online: 20 November 2017; doi:10.1038/nri.2017.125

      This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases.Microglia and macrophages in brain homeostasis and disease, Published online: 2017-11-20; doi:10.1038/nri.2017.1252017-11-20
      DOI: 10.1038/nri.2017.125
       
  • MHC molecules: Immune editing shapes the cancer landscape
    • MHC molecules: Immune editing shapes the cancer landscape

      MHC molecules: Immune editing shapes the cancer landscape, Published online: 13 November 2017; doi:10.1038/nri.2017.129

      NatureArticleSnippet(type=short-summary, markup=

      HLA variation or loss is associated with immune editing in human tumours.

      , isJats=true)MHC molecules: Immune editing shapes the cancer landscape, Published online: 2017-11-13; doi:10.1038/nri.2017.1292017-11-13
      DOI: 10.1038/nri.2017.129
       
  • The diverse functions of the PD1 inhibitory pathway
    • The diverse functions of the PD1 inhibitory pathway

      The diverse functions of the PD1 inhibitory pathway, Published online: 13 November 2017; doi:10.1038/nri.2017.108

      NatureArticleSnippet(type=short-summary, markup=

      In this Review, the authors detail the complex expression patterns and regulation of programmed cell death protein 1 (PD1) and its ligands. The authors focus on the importance of understanding these pathways in order to optimize the efficiency and safety of immune checkpoint blockade in patients.

      , isJats=true)The diverse functions of the PD1 inhibitory pathway, Published online: 2017-11-13; doi:10.1038/nri.2017.1082017-11-13
      DOI: 10.1038/nri.2017.108
       
  • Dendritic cells: Managing migration
    • Dendritic cells: Managing migration

      Dendritic cells: Managing migration, Published online: 13 November 2017; doi:10.1038/nri.2017.128

      NatureArticleSnippet(type=short-summary, markup=

      Lysosomal calcium signalling links antigen uptake by tissue dendritic cells to migration to the lymph nodes.

      , isJats=true)Dendritic cells: Managing migration, Published online: 2017-11-13; doi:10.1038/nri.2017.1282017-11-13
      DOI: 10.1038/nri.2017.128
       
  • Inflammation: Inflammatory memory is skin deep
    • Inflammation: Inflammatory memory is skin deep

      Inflammation: Inflammatory memory is skin deep, Published online: 07 November 2017; doi:10.1038/nri.2017.127

      NatureArticleSnippet(type=short-summary, markup=

      Skin epithelial stem cells show inflammatory memory, which enhances their response to tissue damage.

      , isJats=true)Inflammation: Inflammatory memory is skin deep, Published online: 2017-11-07; doi:10.1038/nri.2017.1272017-11-07
      DOI: 10.1038/nri.2017.127
       
 
 
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