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Journal Cover Nature Reviews Genetics
  [SJR: 32.615]   [H-I: 267]   [245 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1471-0056 - ISSN (Online) 1471-0064
   Published by NPG Homepage  [135 journals]
  • Putting gene essentiality into context
    • Putting gene essentiality into context

      Putting gene essentiality into context, Published online: 12 December 2017; doi:10.1038/nrg.2017.141

      Two articles in this issue of Nature Reviews Genetics discuss our maturing understanding of gene essentiality in cells and humansPutting gene essentiality into context, Published online: 2017-12-12; doi:10.1038/nrg.2017.1412017-12-12
      DOI: 10.1038/nrg.2017.141
       
  • Technique: A miniature living recording device
    • Technique: A miniature living recording device

      Technique: A miniature living recording device, Published online: 11 December 2017; doi:10.1038/nrg.2017.110

      Technique: A miniature living recording deviceTechnique: A miniature living recording device, Published online: 2017-12-11; doi:10.1038/nrg.2017.1102017-12-11
      DOI: 10.1038/nrg.2017.110
       
  • Genetic architecture: the shape of the genetic contribution to human
           traits and disease
    • Genetic architecture: the shape of the genetic contribution to human traits and disease

      Genetic architecture: the shape of the genetic contribution to human traits and disease, Published online: 11 December 2017; doi:10.1038/nrg.2017.101

      Genetic architecture describes the characteristics of genetic variation that are responsible for phenotypic variability. This Review discusses the types of genetic architecture that have been observed, how they can be measured and how genetic architecture informs the scientific and clinical goals of human genetics.Genetic architecture: the shape of the genetic contribution to human traits and disease, Published online: 2017-12-11; doi:10.1038/nrg.2017.1012017-12-11
      DOI: 10.1038/nrg.2017.101
       
  • A change of view: homologous recombination at single-molecule resolution
    • A change of view: homologous recombination at single-molecule resolution

      A change of view: homologous recombination at single-molecule resolution, Published online: 11 December 2017; doi:10.1038/nrg.2017.92

      In this Review, Kaniecki et al. discuss how the use of single-molecule optical microscopy and super-resolution optical microscopy methods has benefited our understanding of homologous recombination by generating detailed insights into the molecules and processes involved.A change of view: homologous recombination at single-molecule resolution, Published online: 2017-12-11; doi:10.1038/nrg.2017.922017-12-11
      DOI: 10.1038/nrg.2017.92
       
  • Stem cells: Regenerating the skin of a young patient
    • Stem cells: Regenerating the skin of a young patient

      Stem cells: Regenerating the skin of a young patient, Published online: 04 December 2017; doi:10.1038/nrg.2017.106

      Stem cells: Regenerating the skin of a young patientStem cells: Regenerating the skin of a young patient, Published online: 2017-12-04; doi:10.1038/nrg.2017.1062017-12-04
      DOI: 10.1038/nrg.2017.106
       
  • Am I ready for CRISPR' A user's guide to genetic screens
    • Am I ready for CRISPR? A user's guide to genetic screens

      Am I ready for CRISPR? A user's guide to genetic screens, Published online: 04 December 2017; doi:10.1038/nrg.2017.97

      The rapid development of CRISPR-based gene manipulation has enabled various approaches for high-throughput functional genomics. This Review guides users through the practicalities of CRISPR-based functional genomics screens, including study design options, best-practice approaches, pitfalls to avoid and data analysis strategies.Am I ready for CRISPR? A user's guide to genetic screens, Published online: 2017-12-04; doi:10.1038/nrg.2017.972017-12-04
      DOI: 10.1038/nrg.2017.97
       
  • Pathogen genomics: Genomics in the time of cholera
    • Pathogen genomics: Genomics in the time of cholera

      Pathogen genomics: Genomics in the time of cholera, Published online: 04 December 2017; doi:10.1038/nrg.2017.105

      Pathogen genomics: Genomics in the time of choleraPathogen genomics: Genomics in the time of cholera, Published online: 2017-12-04; doi:10.1038/nrg.2017.1052017-12-04
      DOI: 10.1038/nrg.2017.105
       
  • Gene expression: SPOTting single RNA molecules transcriptome-wide
    • Gene expression: SPOTting single RNA molecules transcriptome-wide

      Gene expression: SPOTting single RNA molecules transcriptome-wide, Published online: 04 December 2017; doi:10.1038/nrg.2017.107

      Gene expression: SPOTting single RNA molecules transcriptome-wideGene expression: SPOTting single RNA molecules transcriptome-wide, Published online: 2017-12-04; doi:10.1038/nrg.2017.1072017-12-04
      DOI: 10.1038/nrg.2017.107
       
 
 
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