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Nature Reviews Genetics
Journal Prestige (SJR): 34.896
Citation Impact (citeScore): 17
Number of Followers: 259  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1471-0056 - ISSN (Online) 1471-0064
Published by NPG Homepage  [144 journals]
  • Prospecting for pluripotency
    • Prospecting for pluripotency

      Prospecting for pluripotency, Published online: 22 June 2018; doi:10.1038/s41576-018-0030-1

      Unlike most organisms, planaria maintain pluripotent stem cells (PSCs) beyond embryogenesis. A new study reports the prospective identification and isolation of a neoblast subpopulation containing adult PSCs, characterization of which should help uncover the mechanisms underlying pluripotency and tissue regeneration.Prospecting for pluripotency, Published online: 2018-06-22; doi:10.1038/s41576-018-0030-12018-06-22
      DOI: 10.1038/s41576-018-0030-1
       
  • What makes us human'
    • What makes us human?

      What makes us human?, Published online: 20 June 2018; doi:10.1038/s41576-018-0029-7

      A publication in Science reports the sequencing, assembly and comparative analysis of new and improved great ape genomes and provides a stepping stone for the identification of genetic variation specific to humans.What makes us human?, Published online: 2018-06-20; doi:10.1038/s41576-018-0029-72018-06-20
      DOI: 10.1038/s41576-018-0029-7
       
  • Refining the splice region
    • Refining the splice region

      Refining the splice region, Published online: 19 June 2018; doi:10.1038/s41576-018-0028-8

      A study in Genome Research reports the impact of genetic variation near splice sites on human disease and may help prioritize and functionally interpret newly identified variants.Refining the splice region, Published online: 2018-06-19; doi:10.1038/s41576-018-0028-82018-06-19
      DOI: 10.1038/s41576-018-0028-8
       
  • All eyes on rapid adaptive evolution
    • All eyes on rapid adaptive evolution

      All eyes on rapid adaptive evolution, Published online: 15 June 2018; doi:10.1038/s41576-018-0027-9

      A new study reveals that DNA methylation-mediated repression of gene expression regulates early eye development in blind cave morphs of Astyanax mexicanus.All eyes on rapid adaptive evolution, Published online: 2018-06-15; doi:10.1038/s41576-018-0027-92018-06-15
      DOI: 10.1038/s41576-018-0027-9
       
  • Chromosome interaction hubs around nuclear bodies
    • Chromosome interaction hubs around nuclear bodies

      Chromosome interaction hubs around nuclear bodies, Published online: 08 June 2018; doi:10.1038/s41576-018-0026-x

      A paper in Cell presents split–pool recognition of interactions by tag extension (SPRITE), a method that enables the identification of multiple, simultaneously occurring DNA and RNA interactions genome-wide within the nucleus.Chromosome interaction hubs around nuclear bodies, Published online: 2018-06-08; doi:10.1038/s41576-018-0026-x2018-06-08
      DOI: 10.1038/s41576-018-0026-x
       
  • Using genetic data to strengthen causal inference in observational
           research
    • Using genetic data to strengthen causal inference in observational research

      Using genetic data to strengthen causal inference in observational research, Published online: 05 June 2018; doi:10.1038/s41576-018-0020-3

      Various types of observational studies can provide statistical associations between factors, such as between an environmental exposure and a disease state. This Review discusses the various genetics-focused statistical methodologies that can move beyond mere associations to identify (or refute) various mechanisms of causality, with implications for responsibly managing risk factors in health care and the behavioural and social sciences.Using genetic data to strengthen causal inference in observational research, Published online: 2018-06-05; doi:10.1038/s41576-018-0020-32018-06-05
      DOI: 10.1038/s41576-018-0020-3
       
  • The rice genome revolution: from an ancient grain to Green Super Rice
    • The rice genome revolution: from an ancient grain to Green Super Rice

      The rice genome revolution: from an ancient grain to Green Super Rice, Published online: 05 June 2018; doi:10.1038/s41576-018-0024-z

      Genomic technologies are helping researchers to understand the natural genetic variation that exists in wild and cultivated rice populations. Harnessing this genetic variation will be key to developing Green Super Rice varieties with high yield and low environmental costs.The rice genome revolution: from an ancient grain to Green Super Rice, Published online: 2018-06-05; doi:10.1038/s41576-018-0024-z2018-06-05
      DOI: 10.1038/s41576-018-0024-z
       
  • From genome-wide associations to candidate causal variants by statistical
           fine-mapping
    • From genome-wide associations to candidate causal variants by statistical fine-mapping

      From genome-wide associations to candidate causal variants by statistical fine-mapping, Published online: 29 May 2018; doi:10.1038/s41576-018-0016-z

      Fine-mapping is the process by which a trait-associated region from a genome-wide association study (GWAS) is analysed to identify the particular genetic variants that are likely to causally influence the examined trait. This Review discusses the diverse statistical approaches to fine-mapping and their foundations, strengths and limitations, including integration of trans-ethnic human population data and functional annotations.From genome-wide associations to candidate causal variants by statistical fine-mapping, Published online: 2018-05-29; doi:10.1038/s41576-018-0016-z2018-05-29
      DOI: 10.1038/s41576-018-0016-z
       
 
 
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