Journal Cover Nature Methods
  [SJR: 21.715]   [H-I: 189]   [290 followers]  Follow
    
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   ISSN (Print) 1548-7091 - ISSN (Online) 1548-7105
   Published by NPG Homepage  [135 journals]
  • Multicolor quantitative confocal imaging cytometry
    • Multicolor quantitative confocal imaging cytometry

      Multicolor quantitative confocal imaging cytometry, Published online: 13 November 2017; doi:10.1038/nmeth.4503

      NatureArticleSnippet(type=short-summary, markup=

      This resource paper describes the steps involved in carrying out quantitative multicolour imaging in tissue. It is applied to cleared mouse bone and plots the spatial distribution of specific cell populations within the marrow.

      , isJats=true)Multicolor quantitative confocal imaging cytometry, Published online: 2017-11-13; doi:10.1038/nmeth.45032017-11-13
      DOI: 10.1038/nmeth.4503
       
  • Profiling the transcriptome with RNA SPOTs
    • Profiling the transcriptome with RNA SPOTs

      Profiling the transcriptome with RNA SPOTs, Published online: 13 November 2017; doi:10.1038/nmeth.4500

      NatureArticleSnippet(type=short-summary, markup=

      RNA SPOTs adapts sequential fluorescence in situ hybridization (seqFISH) for highly accurate and inexpensive transcriptome-scale or targeted RNA quantification in vitro.

      , isJats=true)Profiling the transcriptome with RNA SPOTs, Published online: 2017-11-13; doi:10.1038/nmeth.45002017-11-13
      DOI: 10.1038/nmeth.4500
       
  • An improved MS2 system for accurate reporting of the mRNA life cycle
    • An improved MS2 system for accurate reporting of the mRNA life cycle

      An improved MS2 system for accurate reporting of the mRNA life cycle, Published online: 13 November 2017; doi:10.1038/nmeth.4502

      NatureArticleSnippet(type=short-summary, markup=

      An improved MS2-tagging system for live-cell RNA imaging allows faithful monitoring of the mRNA life cycle, overcoming degradation artifacts associated with previous versions and having implications regarding mRNA regulation in yeast.

      , isJats=true)An improved MS2 system for accurate reporting of the mRNA life cycle, Published online: 2017-11-13; doi:10.1038/nmeth.45022017-11-13
      DOI: 10.1038/nmeth.4502
       
  • The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral
           resolution and high mass-resolving power
    • The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power

      The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power, Published online: 13 November 2017; doi:10.1038/nmeth.4504

      NatureArticleSnippet(type=short-summary, markup=

      The high spatial resolution of secondary ion mass spectrometry and the high resolving power of the Orbitrap mass spectrometer are combined in a single imaging platform, the 3D OrbiSIMS. The instrument's capabilities for resolving lipids and neurotransmitters in the brain with subcellular spatial resolution, and a drug in a single cell in three dimensions is demonstrated.

      , isJats=true)The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power, Published online: 2017-11-13; doi:10.1038/nmeth.45042017-11-13
      DOI: 10.1038/nmeth.4504
       
  • Isolation and 3D expansion of multipotent Sox9+ mouse lung
           progenitors
    • Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors

      Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors, Published online: 06 November 2017; doi:10.1038/nmeth.4498

      NatureArticleSnippet(type=short-summary, markup=

      This paper describes methods for the 3D culture of mouse lung progenitor cells that can differentiate in vitro and in vivo along all epithelial lineages.

      , isJats=true)Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors, Published online: 2017-11-06; doi:10.1038/nmeth.44982017-11-06
      DOI: 10.1038/nmeth.4498
       
  • The Author File: Alice C. McHardy
    • The Author File: Alice C. McHardy

      The Author File: Alice C. McHardy, Published online: 31 October 2017; doi:10.1038/nmeth.4485

      NatureArticleSnippet(type=standfirst, markup=

      How to run a computational competition energized by modern dance.

      , isJats=true)The Author File: Alice C. McHardy, Published online: 2017-10-31; doi:10.1038/nmeth.44852017-10-31
      DOI: 10.1038/nmeth.4485
       
  • DNA sequencing: Packing, trapping and sequencing
    • DNA sequencing: Packing, trapping and sequencing

      DNA sequencing: Packing, trapping and sequencing, Published online: 31 October 2017; doi:10.1038/nmeth.4487

      NatureArticleSnippet(type=standfirst, markup=

      Ultralow concentrations of DNA can be optically sequenced with SMRT DNA sequencing.

      , isJats=true)DNA sequencing: Packing, trapping and sequencing, Published online: 2017-10-31; doi:10.1038/nmeth.44872017-10-31
      DOI: 10.1038/nmeth.4487
       
  • Stem cells: Antibodies trigger reprogramming
    • Stem cells: Antibodies trigger reprogramming

      Stem cells: Antibodies trigger reprogramming, Published online: 31 October 2017; doi:10.1038/nmeth.4491

      NatureArticleSnippet(type=standfirst, markup=

      Antibodies that initiate signaling cascades and thereby replace reprogramming factors promise an efficient and safe way to produce pluripotent stem cells.

      , isJats=true)Stem cells: Antibodies trigger reprogramming, Published online: 2017-10-31; doi:10.1038/nmeth.44912017-10-31
      DOI: 10.1038/nmeth.4491
       
 
 
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