Journal Cover
Nature Cell Biology
Journal Prestige (SJR): 14.07
Citation Impact (citeScore): 14
Number of Followers: 454  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1465-7392 - ISSN (Online) 1476-4679
Published by NPG Homepage  [144 journals]
  • Single-cell multi-omics sequencing of human early embryos
    • Single-cell multi-omics sequencing of human early embryos

      Single-cell multi-omics sequencing of human early embryos, Published online: 18 June 2018; doi:10.1038/s41556-018-0123-2

      Using scCOOL-seq, Li et al. simultaneously characterize the DNA methylation and chromatin accessibility of the same cell during human preimplantation development.Single-cell multi-omics sequencing of human early embryos, Published online: 2018-06-18; doi:10.1038/s41556-018-0123-22018-06-18
      DOI: 10.1038/s41556-018-0123-2
       
  • Pro-tumorigenic AMPK in glioblastoma
    • Pro-tumorigenic AMPK in glioblastoma

      Pro-tumorigenic AMPK in glioblastoma, Published online: 18 June 2018; doi:10.1038/s41556-018-0129-9

      AMPK is a key metabolic sensor promoting cellular energy homeostasis under low-nutrient conditions and other stresses. However, its role in cancer is context-dependent and not fully understood. A study now shows that glioma stem cells co-opt an AMPK-dependent pathway to rewire metabolism, promoting tumour growth.Pro-tumorigenic AMPK in glioblastoma, Published online: 2018-06-18; doi:10.1038/s41556-018-0129-92018-06-18
      DOI: 10.1038/s41556-018-0129-9
       
  • Dynamic kinetochore size regulation promotes microtubule capture and
           chromosome biorientation in mitosis
    • Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis

      Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis, Published online: 18 June 2018; doi:10.1038/s41556-018-0130-3

      Sacristan et al. show that the dynein adaptor Spindly facilitates oligomerisation of the RZZ complex to expand the kinetochore, after which Spindly-associated dynein compacts the kinetochore to allow for faithful chromosome segregation.Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis, Published online: 2018-06-18; doi:10.1038/s41556-018-0130-32018-06-18
      DOI: 10.1038/s41556-018-0130-3
       
  • Single-cell characterization of haematopoietic progenitors and their
           trajectories in homeostasis and perturbed haematopoiesis
    • Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

      Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis, Published online: 18 June 2018; doi:10.1038/s41556-018-0121-4

      Using a multi-tier scRNA-seq and CRISP-seq approach, Giladi et al. define a transcriptional signature for the naive haematopoietic stem cell state, and follow progenitor plasticity and fate commitment under the influence of cytokines and growth factors.Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis, Published online: 2018-06-18; doi:10.1038/s41556-018-0121-42018-06-18
      DOI: 10.1038/s41556-018-0121-4
       
  • AMP kinase promotes glioblastoma bioenergetics and tumour growth
    • AMP kinase promotes glioblastoma bioenergetics and tumour growth

      AMP kinase promotes glioblastoma bioenergetics and tumour growth, Published online: 18 June 2018; doi:10.1038/s41556-018-0126-z

      Signalling by the energy sensor kinase AMPK is generally tumour suppressive, but Chhipa et al. show that AMPK is upregulated in glioblastoma, where it phosphorylates CREB1 to enhance HIF1α and GABPA transcription and to support tumour bioenergetics.AMP kinase promotes glioblastoma bioenergetics and tumour growth, Published online: 2018-06-18; doi:10.1038/s41556-018-0126-z2018-06-18
      DOI: 10.1038/s41556-018-0126-z
       
  • A single-cell chromatin map of human embryos
    • A single-cell chromatin map of human embryos

      A single-cell chromatin map of human embryos, Published online: 18 June 2018; doi:10.1038/s41556-018-0134-z

      The transition from a fertilized egg to a pluripotent and transcriptionally independent embryo requires multi-layered chromatin regulation. A study now provides simultaneous profiling of chromatin accessibility and DNA methylation in human preimplantation embryos at single-cell resolution.A single-cell chromatin map of human embryos, Published online: 2018-06-18; doi:10.1038/s41556-018-0134-z2018-06-18
      DOI: 10.1038/s41556-018-0134-z
       
  • Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to
           create an epigenetic barrier to somatic cell reprogramming
    • Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming

      Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming, Published online: 15 June 2018; doi:10.1038/s41556-018-0128-x

      Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogrammingPublisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming, Published online: 2018-06-15; doi:10.1038/s41556-018-0128-x2018-06-15
      DOI: 10.1038/s41556-018-0128-x
       
  • Author Correction: Recognition of RNA N 6-methyladenosine by IGF2BP
           proteins enhances mRNA stability and translation
    • Author Correction: Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

      Author Correction: Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation, Published online: 07 June 2018; doi:10.1038/s41556-018-0102-7

      Author Correction: Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translationAuthor Correction: Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation, Published online: 2018-06-07; doi:10.1038/s41556-018-0102-72018-06-07
      DOI: 10.1038/s41556-018-0102-7
       
 
 
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