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Nature Reviews Genetics
Journal Prestige (SJR): 34.896
Citation Impact (citeScore): 17
Number of Followers: 377  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1471-0056 - ISSN (Online) 1471-0064
Published by NPG Homepage  [143 journals]
  • Publisher Correction: The relationship between genome structure and
           function

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      Nature Reviews Genetics, Published online: 14 October 2021; doi:10.1038/s41576-021-00425-w

      Publisher Correction: The relationship between genome structure and functionNature Reviews Genetics, Published online: 2021-10-14; doi:10.1038/s41576-021-00425-w2021-10-14
      DOI: 10.1038/s41576-021-00425-w
       
  • GETting at single-cell chromatin dynamics

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      Nature Reviews Genetics, Published online: 14 October 2021; doi:10.1038/s41576-021-00426-9

      A study in Nature Biotechnology describes single-cell genome and epigenome by transposases sequencing (scGET-seq), which generates euchromatin and heterochromatin profiles from the same cell, and Chromatin Velocity, a computational framework capable of predicting future epigenetic cell fate trajectories from scGET-seq data.Nature Reviews Genetics, Published online: 2021-10-14; doi:10.1038/s41576-021-00426-92021-10-14
      DOI: 10.1038/s41576-021-00426-9
       
  • Foreseeing the principles of genome architecture

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      Nature Reviews Genetics, Published online: 05 October 2021; doi:10.1038/s41576-021-00423-y

      Tom Misteli highlights a 2006 study by Shopland et al., which used relatively simple methods to visualize characteristics of chromosome organization. Their conclusions foreshadowed key concepts in the field: topologically associating domains, compartments and cell-to-cell heterogeneity in genome organization.Nature Reviews Genetics, Published online: 2021-10-05; doi:10.1038/s41576-021-00423-y2021-10-05
      DOI: 10.1038/s41576-021-00423-y
       
  • Overlapping genes in natural and engineered genomes

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      Nature Reviews Genetics, Published online: 05 October 2021; doi:10.1038/s41576-021-00417-w

      The authors review overlapping sequences as fundamental features of prokaryotic, eukaryotic and viral genomes, discussing the diverse topologies and functions of overlapping genes, open reading frames and coding sequences. Moreover, they highlight the potential of harnessing sequence overlaps for synthetic biology approaches.Nature Reviews Genetics, Published online: 2021-10-05; doi:10.1038/s41576-021-00417-w2021-10-05
      DOI: 10.1038/s41576-021-00417-w
       
  • Interplay between chromatin marks in development and disease

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      Nature Reviews Genetics, Published online: 04 October 2021; doi:10.1038/s41576-021-00416-x

      In this Review, Janssen and Lorincz discuss the intricate and multilayered interplay between chromatin marks. Focusing on histone methylation and DNA methylation during mammalian development, they discuss the implications for gene regulation, differentiation and human disease.Nature Reviews Genetics, Published online: 2021-10-04; doi:10.1038/s41576-021-00416-x2021-10-04
      DOI: 10.1038/s41576-021-00416-x
       
  • Detecting ribosomal footprints in single cells

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      Nature Reviews Genetics, Published online: 30 September 2021; doi:10.1038/s41576-021-00422-z

      A study in Nature describes single-cell ribosome sequencing, which advances single-cell genomics by enabling the measurement of translational dynamics in single cells.Nature Reviews Genetics, Published online: 2021-09-30; doi:10.1038/s41576-021-00422-z2021-09-30
      DOI: 10.1038/s41576-021-00422-z
       
  • Abiotic stress responses in plants

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      Nature Reviews Genetics, Published online: 24 September 2021; doi:10.1038/s41576-021-00413-0

      In this Review, Zhang et al. summarize our current understanding of the molecular mechanisms underlying the responses of plants to abiotic stresses, and how this knowledge can be used to improve crop resilience through genetic, chemical and microbial approaches.Nature Reviews Genetics, Published online: 2021-09-24; doi:10.1038/s41576-021-00413-02021-09-24
      DOI: 10.1038/s41576-021-00413-0
       
  • The genetics of obesity: from discovery to biology

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      Nature Reviews Genetics, Published online: 23 September 2021; doi:10.1038/s41576-021-00414-z

      In this Review, Loos and Yeo summarize our current understanding of the genetic underpinnings of monogenic and polygenic obesity. They highlight the commonalities revealed by recent studies and discuss the implications for treatment and prediction of obesity risk.Nature Reviews Genetics, Published online: 2021-09-23; doi:10.1038/s41576-021-00414-z2021-09-23
      DOI: 10.1038/s41576-021-00414-z
       
 
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