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European Journal of Pharmacology
Journal Prestige (SJR): 1.057
Citation Impact (citeScore): 3
Number of Followers: 10  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0014-2999 - ISSN (Online) 1879-0712
Published by Elsevier Homepage  [3281 journals]
  • The Rho kinase (ROCK) inhibitor Y-27632 reduces the β2-adrenoceptor
           density but enhance cAMP formation in primary equine bronchial epithelial
           cells

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      Abstract: Publication date: 15 September 2021Source: European Journal of Pharmacology, Volume 907Author(s): Linda Marie Schellenberg, Ralf Regenthal, Getu Abraham
       
  • Antiseptic mouthwash inhibits antihypertensive and vascular protective
           effects of L-arginine

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      Abstract: Publication date: 15 September 2021Source: European Journal of Pharmacology, Volume 907Author(s): Rose I.M. Batista, Renato C. Nogueira, Graziele C. Ferreira, Gustavo H. Oliveira-Paula, Célio Damacena-Angelis, Lucas C. Pinheiro, Jose E. Tanus-Santos
       
  • Intervertebral foramen injection of plerixafor attenuates neuropathic pain
           after chronic compression of the dorsal root ganglion: Possible
           involvement of the down-regulation of Nav1.8 and Nav1.9

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      Abstract: Publication date: Available online 10 July 2021Source: European Journal of PharmacologyAuthor(s): Fei Yang, Yi-Qing Zou, Min Li, Wen-Jun Luo, Guo-Zhong Chen, Xiao-Zhi Wu
       
  • 1-Methyl tryptophan, an indoleamine 2,3-dioxygenase inhibitor, attenuates
           cardiac and hepatic dysfunction in rats with biliary cirrhosis

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      Abstract: Publication date: Available online 9 July 2021Source: European Journal of PharmacologyAuthor(s): Sevda Shayesteh, Gilles J. Guillemin, Amir Rashidian, Hedyeh Faghir‐Ghanesefat, Ali R. Mani, Seyed Mohammad Tavangar, Ahmad R. Dehpour
       
  • Cytochrome P450 2F2 (CYP2F2) negatively regulates browning in 3T3-L1 white
           adipocytes

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      Abstract: Publication date: Available online 9 July 2021Source: European Journal of PharmacologyAuthor(s): Trang Thi Huyen Dang, Minji Choi, Huong Giang Pham, Jong Won Yun
       
  • Dioscin alleviates lung ischemia/reperfusion injury by regulating
           FXR-mediated oxidative stress, apoptosis, and inflammation

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      Abstract: Publication date: Available online 9 July 2021Source: European Journal of PharmacologyAuthor(s): Lile Dong, Lianhong Yin, Ruomiao Li, Lina Xu, Youwei Xu, Xu Han, Yan Qi
       
  • Ferroptosis as a new therapeutic opportunity for nonviral liver disease

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      Abstract: Publication date: Available online 9 July 2021Source: European Journal of PharmacologyAuthor(s): Min Jia, Hongmei Zhang, Qiaohong Qin, Ying Hou, Xin Zhang, Di Chen, Hong Zhang, Yulong Chen
       
  • Caveolin-1 attenuates acetaminophen aggravated lipid accumulation in
           alcoholic fatty liver by activating mitophagy via the Pink-1/Parkin
           pathway

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      Abstract: Publication date: Available online 9 July 2021Source: European Journal of PharmacologyAuthor(s): Wei Jiang, Jiarong Wang, Weiju Xue, Jiao Xin, Congjian Shi, Jiagen Wen, Xiaowen Feng, Yan Huang, Chengmu Hu
       
  • Aspirin ameliorates pulmonary vascular remodeling in pulmonary
           hypertension by dampening endothelial-to-mesenchymal transition

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      Abstract: Publication date: Available online 8 July 2021Source: European Journal of PharmacologyAuthor(s): Ning Huang, Tian-Tian Zhu, Ting Liu, Xiao-Yue Ge, Di Wang, Hong Liu, Guang-Xuan Zhu, Zheng Zhang, Chang-Ping Hu
       
  • Betaine alleviates right ventricular failure via regulation of Rho A/ROCK
           signaling pathway in rats with pulmonary arterial hypertension

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      Abstract: Publication date: Available online 8 July 2021Source: European Journal of PharmacologyAuthor(s): Yingjie Lv, Pengsheng Ma, Jialing Wang, Qingbin Xu, Jun Fan, Lin Yan, Ping Ma, Ru Zhou
       
  • An insight into the implications of estrogen deficiency and transforming
           growth factor β in antiepileptic drugs-induced bone loss

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      Abstract: Publication date: Available online 7 July 2021Source: European Journal of PharmacologyAuthor(s): Md Jamir Anwar, Sattam K. Alenezi, Danish Mahmood, Faizul Azam, Khalid Saad Alharbi
       
  • Effects of antiviral drug therapy on dynamic thiol/disulphide homeostasis
           and nitric oxide levels in COVID-19 patients

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      Abstract: Publication date: Available online 7 July 2021Source: European Journal of PharmacologyAuthor(s): Ayşe Özlem Mete, Kübra Kocak, Ahmet Saracaloglu, Seniz Demiryürek, Özgür Altınbaş, Abdullah T. Demiryürek
       
  • Mibefradil reduces hepatic glucose output in HepG2 cells via
           Ca2+/calmodulin-dependent protein kinase II-dependent Akt/forkhead box
           O1signaling

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      Abstract: Publication date: Available online 3 July 2021Source: European Journal of PharmacologyAuthor(s): Dai Ying, Shan Mengya, Li Peilin, Zhao Lingong, Ma huan, Xu Jing, Zhang Le, Zhang Kebin, Chen Bin, Yan Jun, Guo Shaodong, Xu Zihui
       
  • Dapagliflozin attenuates steatosis in livers of high-fat diet-induced mice
           and oleic acid-treated L02 cells via regulating AMPK/mTOR pathway

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      Abstract: Publication date: Available online 3 July 2021Source: European Journal of PharmacologyAuthor(s): Jingyi Luo, Pengbo Sun, Yangyang Wang, Yang Chen, Yaoyun Niu, Yipei Ding, Naihan Xu, Yaou Zhang, Weidong Xie
       
  • Discovery of a novel CDK7 inhibitor YPN-005 in small cell lung cancer

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      Abstract: Publication date: Available online 3 July 2021Source: European Journal of PharmacologyAuthor(s): Yun Jung Choi, Hyeonjeong Lee, Da-Som Kim, Dong Ha Kim, Myoung-Hee Kang, Yong-Hee Cho, Chang-Min Choi, Jakyung Yoo, Kwang-Ok Lee, Eun Kyung Choi, Jae Cheol Lee, Jin Kyung Rho
       
  • Latcripin-7A from Lentinula edodes C91-3 induce apoptosis, autophagy, and
           cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting
           PI3K/Akt/mTOR signaling

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      Abstract: Publication date: Available online 2 July 2021Source: European Journal of PharmacologyAuthor(s): Syed Riaz Ud Din, Muhammad Azhar Nisar, Muhammad Noman Ramzan, Muhammad Zubair Saleem, Hassan Ghayas, Bashir Ahmad, Samana Batool, Kashif Kifayat, Xiaorong Guo, Min Huang, Mintao Zhong
       
  • The leukotriene receptor antagonist montelukast in the treatment of
           non-alcoholic steatohepatitis: A proof-of-concept, randomized,
           double-blind, placebo-controlled trial

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      Abstract: Publication date: 5 September 2021Source: European Journal of Pharmacology, Volume 906Author(s): Mahmoud Samy Abdallah, Ahmed Hossam Eldeen, Sally Said Tantawy, Tarek Mohamed Mostafa
       
  • Zinc oxide nanoparticle-triggered oxidative stress and autophagy
           activation in human tenon fibroblasts

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      Abstract: Publication date: Available online 2 July 2021Source: European Journal of PharmacologyAuthor(s): Dadong Guo, Zhe Wang, Lijie Guo, Xuewei Yin, Zonghong Li, Mengxian Zhou, Tuling Li, Chen Chen, Hongsheng Bi
       
  • Molecular signaling of synthetic cannabinoids: Comparison of CB1 receptor
           and TRPV1 channel activation

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      Abstract: Publication date: Available online 2 July 2021Source: European Journal of PharmacologyAuthor(s): Haley K. Andersen, Kenneth B. Walsh
       
  • XHL11, a novel selective EGFR inhibitor, overcomes EGFRT790M-mediated
           resistance in non-small cell lung cancer

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      Abstract: Publication date: Available online 2 July 2021Source: European Journal of PharmacologyAuthor(s): Yi Li, Qing-Long Yu, Tong-Fang Li, Ya-Ni Xiao, Li Zhang, Qiu-Yan Zhang, Chun-Guang Ren, Hong-Lei Xie
       
  • Iso-suillin-induced DNA damage leading to cell cycle arrest and apoptosis
           arised from p53 phosphorylation in A549 cells

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Yongxin Yan, Shengjie Yao, Zhiqiang Jia, Junxia Zhao, Li'an Wang
       
  • Effect of acute and chronic exposure to lovastatin on the anticonvulsant
           action of classical antiepileptic drugs in the mouse maximal
           electroshock-induced seizure model

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Michał Tomaszewski, Dorota Zolkowska, Zbigniew Plewa, Stanisław J. Czuczwar, Jarogniew J. Łuszczki
       
  • Anti-fibrotic effects of p53 activation induced by RNA polymerase I
           inhibitor in primary cardiac fibroblasts

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Shu Pang, Ye Chen, Chaochao Dai, Tengfei Liu, Wenjing Zhang, Jianli Wang, Xiaopei Cui, Xiaosun Guo, Fan Jiang
       
  • Activation of peripheral δ2-opioid receptor prevents
           reperfusion heart injury

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Leonid N. Maslov, Alexander V. Mukhomedzyanov, Sergey Y. Tsibulnikov, M.-Saadeh Suleiman, Igor Khaliulin, Peter R. Oeltgen
       
  • Dual effects of atorvastatin on angiogenesis pathways in the
           differentiation of mesenchymal stem cells

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Solmaz Khalighfard, Vahid Khori, Ali Mohammad Alizadeh, Gelareh Vahabzadeh, Mahboubeh Tajaldini, Sima Sedighi, Zohreh Nozarian, Hamid Khodayari, Saeed Khodayari, Fatemeh Ganji, Ziba Veisi Malekshahi, Tahereh Mirmajidi
       
  • Research progress of phosphatidylinositol 4-kinase and its inhibitors in
           inflammatory diseases

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Yan-ping Li, Reyaj Mikrani, Yi-fan Hu, Mirza Muhammad Faran Ashraf Baig, Muhammad Abbas, Fahad Akhtar, Ming Xu
       
  • A brief review of urate transporter 1 (URAT1) inhibitors for the treatment
           of hyperuricemia and gout: Current therapeutic options and potential
           applications

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      Abstract: Publication date: Available online 1 July 2021Source: European Journal of PharmacologyAuthor(s): Danni Song, Xu Zhao, Fuqi Wang, Gang Wang
       
  • Short-chain fatty acid receptors involved in epithelial acetylcholine
           release in rat caecum

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      Abstract: Publication date: Available online 30 June 2021Source: European Journal of PharmacologyAuthor(s): Jasmin Ballout, Yasutada Akiba, Jonathan D. Kaunitz, Martin Diener
       
  • Sirtuin 1 as the mechanism of action of agents used in the diabetes
           mellitus pharmacotherapy

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      Abstract: Publication date: Available online 30 June 2021Source: European Journal of PharmacologyAuthor(s): Agnieszka Stelmaszyk, Przemysław Mikołajczak, Marzena Dworacka
       
  • Anticancer effects of Traditional Chinese Medicine on
           epithelial-mesenchymal transition(EMT) in breast cancer: Cellular and
           molecular targets

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      Abstract: Publication date: Available online 30 June 2021Source: European Journal of PharmacologyAuthor(s): Yiran Lu, Yu Ding, Jiahui Wei, Song He, Xinmiao Liu, Huihao Pan, Bao Yuan, Qing Liu, Jiabao Zhang
       
  • Sacubitril/valsartan in chronic kidney disease: From pharmacological
           mechanism to clinical application

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      Abstract: Publication date: Available online 30 June 2021Source: European Journal of PharmacologyAuthor(s): Huang Kuang, Xin Huang, Zhifeng Zhou, Xuexin Cheng, Gaosi Xu
       
  • The β2 subunit E155 residue as a proton sensor at the binding site on
           GABA type A receptors

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      Abstract: Publication date: Available online 30 June 2021Source: European Journal of PharmacologyAuthor(s): Michał A. Michałowski, Marta A. Czyżewska, Ilona Iżykowska, Jerzy W. Mozrzymas
       
  • Targeting HMGB1/TLR4/NF-κB signaling pathway by protocatechuic acid
           protects against l-arginine induced acute pancreatitis and multiple organs
           injury in rats

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      Abstract: Publication date: Available online 29 June 2021Source: European Journal of PharmacologyAuthor(s): Marwa E. Abdelmageed, Manar A. Nader, Marwa S. Zaghloul
       
  • Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of
           hepatocellular carcinoma by targeting lipogenesis

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      Abstract: Publication date: 5 September 2021Source: European Journal of Pharmacology, Volume 906Author(s): Huannan Meng, Mengqin Shen, Jiajin Li, Ruixue Zhang, Xi Li, Li Zhao, Gang Huang, Jianjun Liu
       
  • PEX5 prevents cardiomyocyte hypertrophy via suppressing the
           redox-sensitive signaling pathways MAPKs and STAT3

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      Abstract: Publication date: 5 September 2021Source: European Journal of Pharmacology, Volume 906Author(s): Minghui Wang, Jingyan Li, Yanqing Ding, Sidong Cai, Zhuoming Li, Peiqing Liu
       
  • Concomitant use of analgesics and immune checkpoint inhibitors in
           non-small cell lung cancer: A pharmacodynamics perspective

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      Abstract: Publication date: 5 September 2021Source: European Journal of Pharmacology, Volume 906Author(s): Rahmad Aji Prasetya, Marjolein Metselaar-Albers, Ferdi Engels
       
  • New contributions to the drug profile of TNFα inhibitor SPD304: Affinity,
           selectivity and ADMET considerations

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      Abstract: Publication date: Available online 26 June 2021Source: European Journal of PharmacologyAuthor(s): Aïda Mascret, Hadley Mouhsine, Ghada Attia, Damien Cabrera, Mohamed Benchekroun, Patrick Gizzi, Chouki Zerrouki, Najla Fourati, Jean-François Zagury, Maité Sylla-Iyarreta Veitia, Marc Port
       
  • Xanthine oxidoreductase promotes the progression of colitis-associated
           colorectal cancer by causing DNA damage and mediating macrophage M1
           polarization

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      Abstract: Publication date: Available online 24 June 2021Source: European Journal of PharmacologyAuthor(s): Hongling Li, Chengjuan Zhang, Hao Zhang, Haitao Li
       
  • Prostaglandin D2 inhibits mediator release and antigen induced
           bronchoconstriction in the Guinea pig trachea by activation of DP1
           receptors

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      Abstract: Publication date: Available online 24 June 2021Source: European Journal of PharmacologyAuthor(s): Jesper Säfholm, Willem Abma, Jielu Liu, David Balgoma, Alexander Fauland, Johan Kolmert, Craig E. Wheelock, Mikael Adner, Sven-Erik Dahlén
       
  • Apelin/APJ system: A novel therapeutic target for locomotor system
           diseases

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      Abstract: Publication date: Available online 24 June 2021Source: European Journal of PharmacologyAuthor(s): Jingshun Luo, Wei Liu, Fen Feng, Linxi Chen
       
  • Asiatic acid protects articular cartilage through promoting chondrogenesis
           and inhibiting inflammation and hypertrophy in osteoarthritis

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      Abstract: Publication date: Available online 24 June 2021Source: European Journal of PharmacologyAuthor(s): Zhengmeng Yang, Lu Feng, Jianping Huang, Xiaoting Zhang, Weiping Lin, Bin Wang, Liao Cui, Sien Lin, Gang Li
       
  • Ligand modulation of KCNQ-encoded (KV7) potassium channels in the heart
           and nervous system

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      Abstract: Publication date: Available online 24 June 2021Source: European Journal of PharmacologyAuthor(s): Moawiah M. Naffaa, Ola A. Al-Ewaidat
       
  • Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian
           drug

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      Abstract: Publication date: Available online 23 June 2021Source: European Journal of PharmacologyAuthor(s): Pricila Pflüger, Patrícia Pereira, María I. Loza, José Brea, Dolores Viña, Amit Kumar, José A. Fontenla
       
  • Protective effects of dioscin against isoproterenol-induced cardiac
           hypertrophy via adjusting PKCε/ERK-mediated oxidative stress

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      Abstract: Publication date: Available online 23 June 2021Source: European Journal of PharmacologyAuthor(s): Ruomiao Li, Yan Qi, Qianhui Yuan, Lina Xu, Meng Gao, Youwei Xu, Xu Han, Lianhong Yin, Chuntong Liu
       
  • Intermittent administration sodium valproate has a protective effect on
           bone health in ovariectomized rats

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      Abstract: Publication date: Available online 22 June 2021Source: European Journal of PharmacologyAuthor(s): Zhou-Shan Tao, Wan-Shu Zhou, Hong-Guang Xu, Min Yang
       
  • miR-424 induces apoptosis in glioblastoma cells and targets AKT1 and RAF1
           oncogenes from the ERBB signaling pathway

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      Abstract: Publication date: Available online 18 June 2021Source: European Journal of PharmacologyAuthor(s): Fatemeh Gheidari, Ehsan Arefian, Fatemeh Jamshidi Adegani, Mohammad Reza Kalhori, Ehsan Seyedjafari, Mahboubeh Kabiri, Ladan Teimoori-Toolabi, Masoud Soleimani
       
  • Editing flagellin derivatives for exploration of potent radioprotective
           agents

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      Abstract: Publication date: Available online 18 June 2021Source: European Journal of PharmacologyAuthor(s): Tong Shi, Jun Jiang, Meng Gao, Ronglin Ma, Xuejun Chen, Ruihua Zhang, Jianfu Xu, Weili Wang, Shujuan Xu, Xi Liu, Huizhen Zheng, Chen Wang, Liqin Li, Ruibin Li
       
  • Sodium-glucose co-transporter 2 inhibitors in nonalcoholic fatty liver
           disease

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Evangelia S. Makri, Antonis Goulas, Stergios A. Polyzos
       
  • IGF-1 receptor is involved in the regulatory effects of icariin and
           icaritin in astrocytes under basal conditions and after an inflammatory
           challenge

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Wen-Di Zhang, Na Li, Zhong-Rui Du, Mei Zhang, Su Chen, Wen-Fang Chen
       
  • High-dose vitamin D3 c ameliorates renal fibrosis by vitamin D receptor
           activation and inhibiting TGF-β1/Smad3 signaling pathway in 5/6
           nephrectomized rats

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Fujing Wang, Rong Hu, Jiaxing Zhang, Tingting Pei, Zhuo’en He, Liliang Ju, Zhongxiao Han, Mingqing Wang, Wei Xiao
       
  • Tenovin-1 inhibited dengue virus replication through SIRT2

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Yihong Wan, Wenyu Wu, Jiawen Zhang, Liren Li, Yuanda Wan, Xiaodong Tang, Xiaoguang Chen, Shuwen Liu, Xingang Yao
       
  • The analgesic effects of ulinastatin either as a single agent or in
           combination with sufentanil: A novel therapeutic potential for
           postoperative pain

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Zhi-Bin Guo, Li Tang, Li-Ping Wang, Huang-Hui Wu, Chang-Lu Huang, Mei-Xiang Zhan, Zhong-Mou Shi, Chen-Long Yang, Guo-Zhong Chen, Yi-Qing Zou, Fei Yang, Xiao-Zhi Wu
       
  • Inhibition of dynamin-related protein 1 ameliorates the mitochondrial
           ultrastructure via PINK1 and Parkin in the mice model of Parkinson’s
           disease

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Si-Tong Feng, Zhen-Zhen Wang, Yu-He Yuan, Xiao-Le Wang, Zhen-Yu Guo, Jing-Hong Hu, Xu Yan, Nai-Hong Chen, Yi Zhang
       
  • Diosgenin attenuates tumor growth and metastasis in transgenic prostate
           cancer mouse model by negatively regulating both NF-κB/STAT3 signaling
           cascades

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Sakshi Sikka, Muthu K. Shanmugam, Kodappully Sivaraman Siveen, Tina H. Ong, Min Hee Yang, Jong Hyun Lee, Peramaiyan Rajendran, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Tahani Awad Alahmadi, Shireen Vali, Alan Prem Kumar, Gautam Sethi, Lingzhi Wang, Kam Man Hui, Kwang Seok Ahn
       
  • Perspectives for synthetic curcumins in chemoprevention and treatment of
           cancer: an update with promising analogues

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      Abstract: Publication date: Available online 17 June 2021Source: European Journal of PharmacologyAuthor(s): Adeoluwa Adeluola, Abu Hasanat Md Zulfiker, Daniel Brazeau, A.R.M.Ruhul Amin
       
  • Identification and characterization of MAM03055A: a novel bivalent sigma-2
           receptor/TMEM97 ligand with cytotoxic activity

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      Abstract: Publication date: Available online 16 June 2021Source: European Journal of PharmacologyAuthor(s): Cheri Z. Liu, Marco Mottinelli, Hilary E. Nicholson, Bridget M. McVeigh, Neelum K. Wong, Christopher R. McCurdy, Wayne D. Bowen
       
  • Sphingosine-1-phosphate induces myocyte autophagy after myocardial
           infarction through mTOR inhibition

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      Abstract: Publication date: Available online 16 June 2021Source: European Journal of PharmacologyAuthor(s): Li-Guo Yang, Ai-Ling Wang, Lu Li, Hong Yang, Xi Jie, Zong-Feng Zhu, Xiao-Juan Zhang, Hui-Ping Zhao, Rui-Fang Chi, Bao Li, Fu-Zhong Qin, Jia-Pu Wang, Ke Wang
       
  • Triclosan down-regulates fatty acid synthase through microRNAs in HepG2
           cells

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      Abstract: Publication date: Available online 16 June 2021Source: European Journal of PharmacologyAuthor(s): Donglei Sun, Tianhe Zhao, Keyan Long, Mei Wu, Zunzhen Zhang
       
  • Anti-inflammatory effects of a novel phosphodiesterase-4 inhibitor,
           AA6216, in mouse dermatitis models

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      Abstract: Publication date: Available online 15 June 2021Source: European Journal of PharmacologyAuthor(s): Natsuki Kubota-Ishida, Takashi Matsuhira, Chizuko Kaji, Chika Kikuchi, Yuji Tabata
       
  • Impact of protocatechuic acid on high fat diet-induced metabolic syndrome
           sequelae in rats

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      Abstract: Publication date: Available online 12 June 2021Source: European Journal of PharmacologyAuthor(s): Omnia A. Nour, Hamdy A. Ghoniem, Manar A. Nader, Ghada M. Suddek
       
  • Kaempferol inhibits benign prostatic hyperplasia by resisting the action
           of androgen

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      Abstract: Publication date: Available online 12 June 2021Source: European Journal of PharmacologyAuthor(s): Xueni Wang, Junjie Zhu, Huimin Yan, Mengyao Shi, Qiaoqi Zheng, Yu Wang, Yan Zhu, Lin Miao, Xiumei Gao
       
  • Possible involvement of agmatine in neuropharmacological actions of
           metformin in diabetic mice

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      Abstract: Publication date: Available online 12 June 2021Source: European Journal of PharmacologyAuthor(s): Nandkishor Kotagale, Sandip Rahangdale, Anjali Borkar, Kundan Singh, Abhilasha Ikhar, Nikita Takale, Milind Umekar, Brijesh Taksande
       
  • Preclinical evidence of synergism between atovaquone and chemotherapy by
           AMPK-dependent mitochondrial dysfunction

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      Abstract: Publication date: Available online 12 June 2021Source: European Journal of PharmacologyAuthor(s): Fan Xie, Jianhua Gong, Hongxia Tan, Han Zhang, Jingping Ma
       
  • Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic
           review and meta-analysis of clinical studies

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      Abstract: Publication date: Available online 12 June 2021Source: European Journal of PharmacologyAuthor(s): Kiarash Saleki, Shakila Yaribash, Mohammad Banazadeh, Ehsan Hajihosseinlou, Mahdi Gouravani, Amene Saghazadeh, Nima Rezaei
       
  • Nitric oxide modulates tapentadol antinociceptive tolerance and physical
           dependence

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      Abstract: Publication date: Available online 11 June 2021Source: European Journal of PharmacologyAuthor(s): Renata Wolińska, Patrycja Kleczkowska, Anna de Cordé-Skurska, Piotr Poznański, Mariusz Sacharczuk, Joanna Mika, Magdalena Bujalska-Zadrożny
       
  • P2X7 receptor in multifaceted cellular signalling and its relevance as a
           potential therapeutic target in different diseases

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      Abstract: Publication date: 5 September 2021Source: European Journal of Pharmacology, Volume 906Author(s): Abtar Mishra, Assirbad Behura, Ashish Kumar, Lincoln Naik, Ashapoorna Swain, Mousumi Das, Suman Sudha Sarangi, Puja Dokania, Vijaya R. Dirisala, Sujit K. Bhutia, Amit Mishra, Ramandeep Singh, Rohan Dhiman
       
  • Biological activity of 2α,3β,23-trihydroxyolean-12-ene on
           glucose homeostasis

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      Abstract: Publication date: Available online 10 June 2021Source: European Journal of PharmacologyAuthor(s): Allisson Jhonatan Gomes Castro, Luisa Helena Cazarolli, Marisa Jadna Silva Frederico, Betina Fernanda Dambrós, Francieli Kanumfre de Carvalho, Verônica Aiceles de Medeiros Pinto, Cristiane da Fonte Ramos, Fabíola Branco Filippin Monteiro, Moacir Geraldo Pizzolatti, Fátima Regina Mena Barreto Silva
       
  • Sestrin2 suppression aggravates oxidative stress and apoptosis in
           endothelial cells subjected to pharmacologically induced endoplasmic
           reticulum stress

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Munazza T. Fatima, Maram Hasan, Shahenda S. Abdelsalam, Siveen K. Sivaraman, Heba El-Gamal, Muhammad A. Zahid, Mohamed A. Elrayess, Hesham M. Korashy, Asad Zeidan, Aijaz S. Parray, Abdelali Agouni
       
  • Sophoraflavanone M, a prenylated flavonoid from Sophora flavescens Ait.,
           suppresses pro-inflammatory mediators through both NF-κB and JNK/AP-1
           signaling pathways in LPS-primed macrophages

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Yixin Han, Xiaoyu Zhang, Yuan Kang, Yuan Gao, Ximeng Li, Ruijuan Qi, Runlan Cai, Yun Qi
       
  • Scutellarin ameliorates colitis-associated colorectal cancer by
           suppressing Wnt/β-catenin signaling cascade

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Sha Zeng, Li Chen, Qiang Sun, Hui Zhao, Han Yang, Shan Ren, Maolun Liu, Xianli Meng, Haibo Xu
       
  • Novel archetype in psoriasis management bridging molecular dynamics in
           exploring novel therapies

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Krishna Yadav, Deependra Singh, Manju Rawat Singh
       
  • SIRT1/PGC-1α signaling activation by mangiferin attenuates cerebral
           hypoxia/reoxygenation injury in neuroblastoma cells

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Mengfan Chen, Zheng Wang, Wenying Zhou, Chenxi Lu, Ting Ji, Wenwen Yang, Zhenxiao Jin, Ye Tian, Wangrui Lei, Songdi Wu, Qi Fu, Zhen Wu, Xue Wu, Mengzhen Han, Minfeng Fang, Yang Yang
       
  • Alpha lipoic acid priming enhances the hepatoprotective effect of adipose
           derived stem cells in CCl4 induced hepatic injury in-vitro

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Faiza Yaqub, Noreen Latief, Hira Butt, Nadia Naseer, Sheikh Riazuddin
       
  • Effect of anti-hyperglycemic drugs on endoplasmic reticulum (ER) stress in
           human coronary artery endothelial cells

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      Abstract: Publication date: Available online 9 June 2021Source: European Journal of PharmacologyAuthor(s): Poonam Kapadia, Priyanka Bikkina, Angelica Marie Landicho, Shrina Parekh, Michael J. Haas, Arshag D. Mooradian
       
  • Novel small molecule inhibitors of the transcription factor ETS-1 and
           their antitumor activity against hepatocellular carcinoma

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      Abstract: Publication date: Available online 8 June 2021Source: European Journal of PharmacologyAuthor(s): Yamin Jie, Guijun Liu, Mingyan E, Ying Li, Guo Xu, Jingjing Guo, Yinyin Li, Guanghua Rong, Yongwu Li, Anxin Gu
       
  • ASIC1a promotes acidic microenvironment-induced HCC cells migration and
           invasion by inducing autophagy

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      Abstract: Publication date: Available online 8 June 2021Source: European Journal of PharmacologyAuthor(s): Yinghong Wang, Jin Zhang, Peng Jiang, Kai Li, Yancai Sun, Yan Huang
       
  • Synthesis, molecular docking, dynamic simulation and pharmacological
           characterization of potent multifunctional agent (dual GPR40-PPARγ
           agonist) for the treatment of experimental type 2 diabetes

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      Abstract: Publication date: Available online 8 June 2021Source: European Journal of PharmacologyAuthor(s): Sergio Hidalgo-Figueroa, Ana Rodríguez-Luévano, Julio C. Almanza-Pérez, Abraham Giacoman-Martínez, Rolffy Ortiz-Andrade, Ismael León-Rivera, Gabriel Navarrete-Vázquez
       
  • Peroxisome proliferator-activated receptor agonist (pioglitazone) with
           exogenous adiponectin ameliorates arterial stiffness and oxidative stress
           in diabetic Wistar Kyoto rats

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      Abstract: Publication date: Available online 7 June 2021Source: European Journal of PharmacologyAuthor(s): Sheryar Afzal, Munavvar Abdul Sattar, Edward James Johns, Olorunfemi.A. Eseyin
       
  • Efficacy and safety of Dihydroorotate dehydrogenase (DHODH) inhibitors
           “Leflunomide” and “Teriflunomide” in Covid-19: A narrative review.
           

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      Abstract: Publication date: Available online 7 June 2021Source: European Journal of PharmacologyAuthor(s): Hardeep Kaur, Phulen Sarma, Anusuya Bhattacharyya, Saurabh Sharma, Neeraj Chhimpa, Manisha Prajapat, Ajay Prakash, Subodh Kumar, Ashutosh Singh, Rahul Singh, Pramod Avti, Prasad Thota, Bikash Medhi
       
  • Clinical efficacy of zinc supplementation in improving antioxidant defense
           system: a comprehensive systematic review and time-response meta-analysis
           of controlled clinical trials

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      Abstract: Publication date: Available online 6 June 2021Source: European Journal of PharmacologyAuthor(s): Amir Hossein Faghfouri, Meysam Zarezadeh, Baharak Aghapour, Azimeh Izadi, Helya Rostamkhani, Amin Majnouni, Ahmed Abu-Zaid, Hamed Kord Varkaneh, Zohreh Ghoreishi, Alireza Ostadrahimi
       
  • Amelioration of cognitive deficit in zebrafish by an undescribed
           anthraquinone from Juglans regia L.: An in-silico, in-vitro and in-vivo
           approach

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      Abstract: Publication date: Available online 4 June 2021Source: European Journal of PharmacologyAuthor(s): Shinde Bhagatsing Devidas, Shubham Nilkanth Rahmatkar, Rahul Singh, Nitisha Sendri, Rituraj Purohit, Damanpreet Singh, Pamita Bhandari
       
  • Chondroprotective and antiarthritic effects of Galangin in Osteoarthritis:
           An in Vitro and in Vivo Study

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      Abstract: Publication date: Available online 4 June 2021Source: European Journal of PharmacologyAuthor(s): Xiaojian Huang, Wenbin Pei, Bowei Ni, Rui Zhang, Hongbo You
       
  • mGlu2/3 receptor in the prelimbic cortex is implicated in stress
           resilience and vulnerability in mice

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      Abstract: Publication date: Available online 4 June 2021Source: European Journal of PharmacologyAuthor(s): Xiao-Yuan Jing, Yan Wang, Hua-Wei Zou, Zi-Lin Li, Ying-Juan Liu, Lai-Fu Li
       
  • Novel inhibitor of OCT1 enhances the sensitivity of human esophageal
           squamous cell carcinoma cells to antitumor agents

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      Abstract: Publication date: Available online 2 June 2021Source: European Journal of PharmacologyAuthor(s): Xiao-zheng Zou, Xiu-hua Zhou, Ying-qi Feng, Jun-feng Hao, Bing Liang, Meng-wei Jia
       
  • Imatinib inhibits the malignancy of hepatocellular carcinoma by
           suppressing autophagy

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      Abstract: Publication date: Available online 1 June 2021Source: European Journal of PharmacologyAuthor(s): Meng-Chao Xiao, Hui Qian, Chen-Kai Huang, Bai-Nan Zheng, Fang-Zhi Yan, Fang Liu, Xin Zhang, Shi-Jie Chen, Cheng Luo, Wei-Fen Xie
       
  • Gliquidone ameliorates hepatic insulin resistance in
           streptozotocin-induced diabetic Sur1 -/- rats

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      Abstract: Publication date: Available online 1 June 2021Source: European Journal of PharmacologyAuthor(s): Rui Zhang, Xiaojun Zhou, Qiqi Sheng, Qian Zhang, Tianyue Xie, Chunmei Xu, Zhiwei Zou, Jianjun Dong, Lin Liao
       
  • Inhibition of double stranded RNA dependent protein kinase (PKR) abrogates
           isoproterenol induced myocardial ischemia in vitro in cultured
           cardiomyocytes and in vivo in wistar rats

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      Abstract: Publication date: Available online 1 June 2021Source: European Journal of PharmacologyAuthor(s): Sureshbabu Mangali, Audesh Bhat, Deepika Dasari, Dharmarajan Sriram, Arti Dhar
       
  • An evidence update on the protective mechanism of tangeretin against
           neuroinflammation based on network pharmacology prediction and
           transcriptomic analysis

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      Abstract: Publication date: Available online 1 June 2021Source: European Journal of PharmacologyAuthor(s): Shuo Lv, Qiyang Chen, Zhenqing Li, Zhiqin Zhou
       
  • Identification and molecular study on the interaction of Schisandrin C
           with human 5-HT3A receptor

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      Abstract: Publication date: Available online 31 May 2021Source: European Journal of PharmacologyAuthor(s): Sanung Eom, Jaeeun Lee, Yeong-Bin Baek, Hye Duck Yeom, Shinhui Lee, Chaelin Kim, Youngseo Park, Sang-Ik Park, Chang-Min Lee, Junho H. Lee
       
  • HO-1: A new potential therapeutic target to combat osteoporosis

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      Abstract: Publication date: Available online 31 May 2021Source: European Journal of PharmacologyAuthor(s): Jingmin Che, Jiancheng Yang, Bin Zhao, Peng Shang
       
  • A novel evodiamine amino derivative as a PI3K/AKT signaling pathway
           modulator that induces apoptosis in small cell lung cancer cells

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      Abstract: Publication date: Available online 31 May 2021Source: European Journal of PharmacologyAuthor(s): Tingting Wang, Di Qi, Xueyuan Hu, Na Li, Xue Zhang, Hongming Liu, Cailing Zhong, Jingqing Zhang
       
  • Corilagin ameliorates atherosclerosis by regulating MMP-1, -2, and -9
           expression in vitro and in vivo

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      Abstract: Publication date: Available online 29 May 2021Source: European Journal of PharmacologyAuthor(s): Yiting Tao, Li Zhang, Renhua Yang, Yongzhao Yang, Haonan Jin, Xiaochao Zhang, Qin Hu, Bo He, Zhiqiang Shen, Peng Chen
       
  • A novel all-trans retinoic acid derivative regulates cell cycle and
           differentiation of myelodysplastic syndrome cells by USO1

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      Abstract: Publication date: Available online 29 May 2021Source: European Journal of PharmacologyAuthor(s): Shufang Li, Ge Deng, Jingwen Su, Ke Wang, Cong Wang, Lanlan Li, Sujing Song, Xiaoqing Peng, Feihu Chen
       
  • Biased agonists with less glucagon-like peptide-1 receptor-mediated
           endocytosis prolong hypoglycaemic effects

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      Abstract: Publication date: Available online 26 May 2021Source: European Journal of PharmacologyAuthor(s): Qiang Wu, Song Chen, Hanchen Zhu, Na Xu, Qianhua Yang, Wenbing Yao, Xiangdong Gao
       
  • Mitochondrial dysfunction and apoptosis are attenuated through activation
           of AMPK/GSK-3β/PP2A pathway in Parkinson’s disease

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      Abstract: Publication date: Available online 26 May 2021Source: European Journal of PharmacologyAuthor(s): Jianhua Su, Junhua Zhang, Rui Bao, Changbo Xia, Yu Zhang, Zhujun Zhu, Qi Lv, Yingjie Qi, Jianqin Xue
       
  • The proarrhythmic effects of hypothermia in atria isolated from
           5-HT4-receptor-overexpressing mice

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      Abstract: Publication date: Available online 25 May 2021Source: European Journal of PharmacologyAuthor(s): Ulrich Gergs, Tobias Brückner, Britt Hofmann, Joachim Neumann
       
  • BDNF modulated KCC2 ubiquitylation in spinal cord dorsal horn of mice

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      Abstract: Publication date: Available online 25 May 2021Source: European Journal of PharmacologyAuthor(s): Juan-Juan Ma, Tian-Yu Zhang, Xin-Tong Diao, Lin Yao, Yin-Xia Li, Zhan-Wei Suo, Xian Yang, Xiao-Dong Hu, Yan-Ni Liu
       
  • Apigenin acts as a partial agonist action at estrogen receptors in
           vivo

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      Abstract: Publication date: Available online 25 May 2021Source: European Journal of PharmacologyAuthor(s): Lu Yao, Zhuoyan Fan, Shiwen Han, Na Sun, Huilian Che
       
  • Inhibiting Wnt production by downregulating prostaglandins to prevent
           colon tumor formation by aspirin

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      Abstract: Publication date: Available online 23 May 2021Source: European Journal of PharmacologyAuthor(s): Yaqian Feng, Lei Tao, Guoqiang Wang, Zhen Li, Mingming Yang, Weishen He, Xincheng Zhong, Yong Zhang, Jinliang Yang, Shinghu Cheung, Fiona McDonald, Ligong Chen
       
  • Antitussive effects of NaV 1.7 blockade in guinea pigs

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      Abstract: Publication date: Available online 16 May 2021Source: European Journal of PharmacologyAuthor(s): Li Yu, Kojun Tsuji, Izumi Ujihara, Qi Liu, Nikoleta Pavelkova, Takanori Tsujimura, Makoto Inoue, Sonya Meeker, Eric Nisenbaum, Jeff S. McDermott, Jeff Krajewski, Bradley J. Undem, Marian Kollarik, Brendan J. Canning
       
 
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