Subjects -> STATISTICS (Total: 130 journals)
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- Reflecting on Andy Grieve's influence and innovation: A personal
perspective-
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Authors:
Mike K. Smith
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 702-705, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2220 Issue No: Vol. 21, No. 4 (2022)
- The cross‐over of statistical thinking and practices: A pandemic
catalyst-
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Authors:
Andrew D. Garrett
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 778-789, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2221 Issue No: Vol. 21, No. 4 (2022)
- From innovative thinking to pharmaceutical industry implementation: Some
success stories-
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Authors:
Rosalind Walley; Nigel Brayshaw Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 712-719, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2222 Issue No: Vol. 21, No. 4 (2022)
- Viewpoint: Do not resurrect the two‐stage procedure
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Authors:
Stephen Senn
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 808-814, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2224 Issue No: Vol. 21, No. 4 (2022)
- The design and analysis of vaccine trials for COVID‐19 for the
purpose of estimating efficacy-
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Authors:
Stephen Senn
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 790-807, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2226 Issue No: Vol. 21, No. 4 (2022)
- Simulation‐based sequential design
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Authors:
Peter Müller; Yunshan Duan,
Mauricio Garcia Tec Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 729-739, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2216 Issue No: Vol. 21, No. 4 (2022)
- Rationale for the update algorithm of the graphical approach to
sequentially rejective multiple test procedures-
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Authors:
Willi Maurer; Frank Bretz,
Martin Posch Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 757-763, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2227 Issue No: Vol. 21, No. 4 (2022)
- Study‐design in pandemics: From surveillance and
performance‐evaluation to licensing and pharmacovigilance-
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Authors:
Sheila M. Bird
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 764-777, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2217 Issue No: Vol. 21, No. 4 (2022)
- The Acute Stroke Therapy by Inhibition of Neutrophils study – Key
features and impact-
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Authors:
Simon Kirby; Christy Chuang‐Stein Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 720-728, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2218 Issue No: Vol. 21, No. 4 (2022)
- Do statisticians count' A prior and posterior viewpoint
-
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Authors:
Margaret Jones; Gemma Hodgson Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 706-711, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2229 Issue No: Vol. 21, No. 4 (2022)
- Informed decision‐making: Statistical methodology for surrogacy
evaluation and its role in licensing and reimbursement assessments-
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Authors:
Christopher J. Weir; Rod S. Taylor Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 740-756, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2219 Issue No: Vol. 21, No. 4 (2022)
- A note from the editors
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Stephen Senn; Mike K. Smith Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 700-700, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2242 Issue No: Vol. 21, No. 4 (2022)
- Issue Information
-
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Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 697-699, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2136 Issue No: Vol. 21, No. 4 (2022)
- Foreword
-
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Authors:
Adrian Smith
Abstract: Pharmaceutical Statistics, Volume 21, Issue 4, Page 701-701, July/August 2022. PubDate: 2022-07-12T12:00:00-07:00 DOI: 10.1002/pst.2243 Issue No: Vol. 21, No. 4 (2022)
- Key considerations for choosing a statistical method to deal with
incomplete treatment adherence in pragmatic trials-
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Authors:
Md. Belal Hossain; Mohammad Ehsanul Karim Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-08-03T03:19:22-07:00 DOI: 10.1002/pst.2258
- Response to the letter to the editor regarding our article ‘statistical
methodology for highly variable compounds: A novel design approach for the ofatumumab phase 2 bioequivalence study’ https://doi.org/10.1002/pst.2233-
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Authors:
Byron Jones; Bingbing Li,
Morten Bagger,
Alex Goodyear,
Inga Ludwig Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-20T05:27:43-07:00 DOI: 10.1002/pst.2254
- Comments on “Statistical methodology for highly variable compounds: A
novel design approach for the Ofatumumab phase 2 bioequivalence study”-
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Authors:
Wanjie Sun; Donald J. Schuirmann,
Stella Grosser Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-20T05:17:53-07:00 DOI: 10.1002/pst.2255
- Evaluating response‐adaptive randomization procedures for recurrent
events and terminal event data using a composite endpoint-
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Authors:
Yu‐Lin Mau; Pei‐Fang Su Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-19T06:39:29-07:00 DOI: 10.1002/pst.2253
- A Bayesian piecewise exponential phase II design for monitoring a
time‐to‐event endpoint-
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Authors:
Yun Qing; Peter F. Thall,
Ying Yuan Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-18T10:33:46-07:00 DOI: 10.1002/pst.2256
- Left truncation in linked data: A practical guide to understanding left
truncation and applying it using SAS and R-
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Authors:
Yanling Jin; Thanh G. N. Ton,
Devin Incerti,
Sylvia Hu Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-17T06:40:17-07:00 DOI: 10.1002/pst.2257
- CUSUMIN: A cumulative sum interval design for cancer phase I dose finding
studies-
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Authors:
Tomoyoshi Hatayama; Seiichi Yasui Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-07-14T06:20:20-07:00 DOI: 10.1002/pst.2247
- Improving early phase oncology clinical trial design: A case study
-
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Authors:
Alan J. Phillips; Timothy P. Clark Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-29T12:09:37-07:00 DOI: 10.1002/pst.2252
- Win ratio approach for analyzing composite time‐to‐event endpoint with
opposite treatment effects in its components-
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Authors:
Ran Liao; Sujatro Chakladar,
Margaret Gamalo Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-29T02:19:24-07:00 DOI: 10.1002/pst.2248
- Estimators for handling COVID‐19‐related intercurrent events with a
hypothetical strategy-
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Authors:
Florian Lasch; Lorenzo Guizzaro Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-28T01:09:11-07:00 DOI: 10.1002/pst.2244
- Win statistics (win ratio, win odds, and net benefit) can complement one
another to show the strength of the treatment effect on time‐to‐event outcomes-
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Authors:
Gaohong Dong; Bo Huang,
Johan Verbeeck,
Ying Cui,
James Song,
Margaret Gamalo‐Siebers,
Duolao Wang,
David C. Hoaglin,
Yodit Seifu,
Tobias Mütze,
John Kolassa Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-27T01:24:01-07:00 DOI: 10.1002/pst.2251
- A semi‐mechanistic dose‐finding design in oncology using
pharmacokinetic/pharmacodynamic modeling-
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Authors:
Xiao Su; Yisheng Li,
Peter Müller,
Chia‐Wei Hsu,
Haitao Pan,
Kim‐Anh Do Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-24T01:44:37-07:00 DOI: 10.1002/pst.2249
- A MCP‐Mod approach to designing and analyzing survival trials with
potential non‐proportional hazards-
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Authors:
Xiaodong Luo; Yuan Sun,
Zhixing Xu Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-23T03:59:52-07:00 DOI: 10.1002/pst.2241
- Propensity score matching and stratification using multiparty data without
pooling-
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Authors:
Jixian Wang; Roland Marion‐Gallois Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-22T10:54:35-07:00 DOI: 10.1002/pst.2250
- Weighted log‐rank test to compare two survival functions in the presence
of dependent censoring-
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Authors:
Philippe Flandre
Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-16T04:03:56-07:00 DOI: 10.1002/pst.2245
- Confirmatory efficacy testing for individual dose–placebo comparisons
using serial gatekeeping procedure in dose‐finding trials with multiple comparison procedures–modeling-
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Authors:
Yusuke Yamaguchi; Toshifumi Sugitani,
Satoshi Yoshida,
Kazushi Maruo Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-16T02:54:20-07:00 DOI: 10.1002/pst.2246
- Estimation of treatment effects in short‐term depression studies. An
evaluation based on the ICH E9(R1) estimands framework-
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Authors:
Marian Mitroiu; Steven Teerenstra,
Katrien Oude Rengerink,
Frank Pétavy,
Kit C. B. Roes Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-06-09T05:42:54-07:00 DOI: 10.1002/pst.2214
- Optimal unplanned design modification in adaptive two‐stage trials
-
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Authors:
Maximilian Pilz; Carolin Herrmann,
Geraldine Rauch,
Meinhard Kieser Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-23T09:00:31-07:00 DOI: 10.1002/pst.2228
- Statistical methodology for highly variable compounds: A novel design
approach for the Ofatumumab Phase 2 bioequivalence study-
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Authors:
Byron Jones; Bingbing Li,
Morten Bagger,
Alex Goodyear,
Inga Ludwig Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-23T08:10:16-07:00 DOI: 10.1002/pst.2233
- Empirical likelihood inference for area under the receiver operating
characteristic curve using ranked set samples-
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Authors:
Chul Moon; Xinlei Wang,
Johan Lim Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-20T04:28:53-07:00 DOI: 10.1002/pst.2230
- Standard and reference‐based conditional mean imputation
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Authors:
Marcel Wolbers; Alessandro Noci,
Paul Delmar,
Craig Gower‐Page,
Sean Yiu,
Jonathan W. Bartlett Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-19T03:28:44-07:00 DOI: 10.1002/pst.2234
- The utilities and pitfalls of stratified analysis in challenging
situations-
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Authors:
Jin Wang
Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-16T06:22:53-07:00 DOI: 10.1002/pst.2232
- 2 stage subgroup‐specific time‐to‐event (2S‐Sub‐TITE): An
adaptive two‐stage time‐to‐toxicity design for subgroup‐specific dose finding in phase I oncology trials-
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Authors:
Alana McGovern; Andrew G. Chapple,
Clement Ma Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-12T11:59:53-07:00 DOI: 10.1002/pst.2231
- A Bayesian latent class model for predicting gestational age in health
administrative data-
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Authors:
Shuang Wang; Gavino Puggioni,
Xuerong Wen Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-10T05:00:29-07:00 DOI: 10.1002/pst.2225
- Practical guide to sample size calculations: Installation of the app
SampSize-
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Authors:
Laura Flight; Steven A. Julious Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-10T03:34:43-07:00 DOI: 10.1002/pst.2215
- Doubly‐robust methods for differences in restricted mean lifetimes using
pseudo‐observations-
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Authors:
Sangbum Choi; Taehwa Choi,
Hye‐Young Lee,
Sung Won Han,
Dipankar Bandyopadhyay Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-05-07T02:54:57-07:00 DOI: 10.1002/pst.2223
- A flexible mixed data model applied to claims data for post‐market
surveillance of prescription drug safety behavior-
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Authors:
Harris Butler; John D. Rice,
Nichole E. Carlson,
Elaine H. Morrato Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-04-03T08:37:42-07:00 DOI: 10.1002/pst.2213
- Eliciting judgements about dependent quantities of interest: The SHeffield
ELicitation Framework extension and copula methods illustrated using an asthma case study-
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Authors:
Björn Holzhauer; Lisa V. Hampson,
John Paul Gosling,
Björn Bornkamp,
Joseph Kahn,
Markus R. Lange,
Wen‐Lin Luo,
Caterina Brindicci,
David Lawrence,
Steffen Ballerstedt,
Anthony O'Hagan Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-04-03T06:28:14-07:00 DOI: 10.1002/pst.2212
- Treatment‐specific marginal structural Cox model for the effect of
treatment discontinuation-
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Authors:
Dana Johnson; Karen Pieper,
Shu Yang Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-31T03:09:47-07:00 DOI: 10.1002/pst.2211
- Confidence intervals for point‐of‐stabilization of content
uniformity-
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Authors:
Zdeněk Hlávka; Petr Míchal,
Martin Otava Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-28T05:18:27-07:00 DOI: 10.1002/pst.2207
- Geometric approaches to assessing the numerical feasibility for conducting
matching‐adjusted indirect comparisons-
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Authors:
Ekkehard Glimm; Lillian Yau Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-28T04:02:42-07:00 DOI: 10.1002/pst.2210
- SCI: A Bayesian adaptive phase I/II dose‐finding design accounting for
semi‐competing risks outcomes for immunotherapy trials-
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Authors:
Yifei Zhang; Beibei Guo,
Sha Cao,
Chi Zhang,
Yong Zang Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-24T10:57:57-07:00 DOI: 10.1002/pst.2209
- A two‐stage adaptive clinical trial design with data‐driven subgroup
identification at interim analysis-
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Authors:
Sarah E. Johnston; Ilya Lipkovich,
Alex Dmitrienko,
Yan Daniel Zhao Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-24T01:39:17-07:00 DOI: 10.1002/pst.2208
- Assessment of pharmacokinetic linearity after repeated drug administration
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Authors:
Alexander Bauer; Matts Kagedal,
Martin J. Wolfsegger Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-17T04:26:15-07:00 DOI: 10.1002/pst.2206
- The importance of using ordinal scores for patient classification based on
health‐related quality of life trajectories-
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Authors:
Antoine Barbieri; Florence Cousson‐Gélie,
Louise Baussard,
Sophie Gourgou,
Christian Lavergne,
Caroline Mollevi Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-15T04:43:17-07:00 DOI: 10.1002/pst.2205
- Bayesian adaptive randomization design incorporating propensity
score‐matched historical controls-
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Authors:
Ryo Sawamoto; Koji Oba,
Yutaka Matsuyama Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-12T03:45:24-08:00 DOI: 10.1002/pst.2203
- Analysis of an incomplete binary outcome dichotomized from an underlying
continuous variable in clinical trials-
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Authors:
Chenchen Ma; Xin Shen,
Yongming Qu,
Yu Du Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-11T08:18:30-08:00 DOI: 10.1002/pst.2204
- Estimating survival parameters under conditionally independent left
truncation-
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Arjun Sondhi
Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-03-09T03:51:12-08:00 DOI: 10.1002/pst.2202
- Pairwise joint modeling of clustered and high‐dimensional outcomes with
covariate missingness in pediatric pneumonia care-
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Susan Gachau; Edmund Njeru Njagi,
Geert Molenberghs,
Nelson Owuor,
Rachel Sarguta,
Mike English,
Philip Ayieko Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-24T03:30:03-08:00 DOI: 10.1002/pst.2197
- Estimation and expected sample size in Simon's two stage designs that stop
as early as possible-
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Antonios Daletzakis; Rutger Bor,
Marianne A. Jonker,
Kit C. B. Roes,
Harm Tinteren Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-22T12:10:40-08:00 DOI: 10.1002/pst.2200
- Sample size re‐estimation for response‐adaptive randomized
clinical trials-
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Xin Li; Feifang Hu Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-22T04:02:37-08:00 DOI: 10.1002/pst.2199
- Utilizing restricted mean duration of response for efficacy evaluation of
cancer treatments-
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Bo Huang; Lu Tian Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-21T08:48:47-08:00 DOI: 10.1002/pst.2198
- Incorporating historical controls in clinical trials with longitudinal
outcomes using the modified power prior-
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Hongchao Qi; Dimitris Rizopoulos,
Emmanuel Lesaffre,
Joost Rosmalen Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-06T09:48:53-08:00 DOI: 10.1002/pst.2195
- Estimands in observational studies: Some considerations beyond ICH E9 (R1)
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Authors:
Heng Li; Chenguang Wang,
Wei‐Chen Chen,
Nelson Lu,
Changhong Song,
Ram Tiwari,
Yunling Xu,
Lilly Q. Yue Abstract: Pharmaceutical Statistics, EarlyView. PubDate: 2022-02-06T08:58:06-08:00 DOI: 10.1002/pst.2196
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