Subjects -> MATHEMATICS (Total: 1013 journals)
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    - MATHEMATICS (714 journals)
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MATHEMATICS (714 journals)            First | 1 2 3 4     

Showing 601 - 538 of 538 Journals sorted alphabetically
Research in the Mathematical Sciences     Open Access  
Research Journal of Pure Algebra     Open Access   (Followers: 1)
Researches in Mathematics     Open Access  
Results in Control and Optimization     Open Access  
Results in Mathematics     Hybrid Journal  
Results in Nonlinear Analysis     Open Access  
Review of Symbolic Logic     Full-text available via subscription   (Followers: 2)
Reviews in Mathematical Physics     Hybrid Journal   (Followers: 1)
Revista Baiana de Educação Matemática     Open Access  
Revista Bases de la Ciencia     Open Access  
Revista BoEM - Boletim online de Educação Matemática     Open Access  
Revista Colombiana de Matemáticas     Open Access   (Followers: 1)
Revista de Ciencias     Open Access  
Revista de Educación Matemática     Open Access  
Revista de la Escuela de Perfeccionamiento en Investigación Operativa     Open Access  
Revista de la Real Academia de Ciencias Exactas, Fisicas y Naturales. Serie A. Matematicas     Partially Free  
Revista de Matemática : Teoría y Aplicaciones     Open Access   (Followers: 1)
Revista Digital: Matemática, Educación e Internet     Open Access  
Revista Electrónica de Conocimientos, Saberes y Prácticas     Open Access  
Revista Integración : Temas de Matemáticas     Open Access  
Revista Internacional de Sistemas     Open Access  
Revista Latinoamericana de Etnomatemática     Open Access  
Revista Latinoamericana de Investigación en Matemática Educativa     Open Access  
Revista Matemática Complutense     Hybrid Journal  
Revista REAMEC : Rede Amazônica de Educação em Ciências e Matemática     Open Access  
Revista SIGMA     Open Access  
Ricerche di Matematica     Hybrid Journal  
RMS : Research in Mathematics & Statistics     Open Access  
Royal Society Open Science     Open Access   (Followers: 7)
Russian Journal of Mathematical Physics     Full-text available via subscription  
Russian Mathematics     Hybrid Journal  
Sahand Communications in Mathematical Analysis     Open Access  
Sampling Theory, Signal Processing, and Data Analysis     Hybrid Journal  
São Paulo Journal of Mathematical Sciences     Hybrid Journal  
Science China Mathematics     Hybrid Journal   (Followers: 1)
Science Progress     Full-text available via subscription   (Followers: 1)
Sciences & Technologie A : sciences exactes     Open Access  
Selecta Mathematica     Hybrid Journal   (Followers: 1)
SeMA Journal     Hybrid Journal  
Semigroup Forum     Hybrid Journal   (Followers: 1)
Set-Valued and Variational Analysis     Hybrid Journal  
SIAM Journal on Applied Mathematics     Hybrid Journal   (Followers: 11)
SIAM Journal on Computing     Hybrid Journal   (Followers: 11)
SIAM Journal on Control and Optimization     Hybrid Journal   (Followers: 18)
SIAM Journal on Discrete Mathematics     Hybrid Journal   (Followers: 8)
SIAM Journal on Financial Mathematics     Hybrid Journal   (Followers: 3)
SIAM Journal on Mathematics of Data Science     Hybrid Journal   (Followers: 1)
SIAM Journal on Matrix Analysis and Applications     Hybrid Journal   (Followers: 3)
SIAM Journal on Optimization     Hybrid Journal   (Followers: 12)
Siberian Advances in Mathematics     Hybrid Journal  
Siberian Mathematical Journal     Hybrid Journal  
Sigmae     Open Access  
SILICON     Hybrid Journal  
SN Partial Differential Equations and Applications     Hybrid Journal  
Soft Computing     Hybrid Journal   (Followers: 7)
Statistics and Computing     Hybrid Journal   (Followers: 14)
Stochastic Analysis and Applications     Hybrid Journal   (Followers: 3)
Stochastic Partial Differential Equations : Analysis and Computations     Hybrid Journal   (Followers: 2)
Stochastic Processes and their Applications     Hybrid Journal   (Followers: 6)
Stochastics and Dynamics     Hybrid Journal   (Followers: 2)
Studia Scientiarum Mathematicarum Hungarica     Full-text available via subscription   (Followers: 1)
Studia Universitatis Babeș-Bolyai Informatica     Open Access  
Studies In Applied Mathematics     Hybrid Journal   (Followers: 1)
Studies in Mathematical Sciences     Open Access   (Followers: 1)
Superficies y vacio     Open Access  
Suska Journal of Mathematics Education     Open Access   (Followers: 1)
Swiss Journal of Geosciences     Hybrid Journal   (Followers: 1)
Synthesis Lectures on Algorithms and Software in Engineering     Full-text available via subscription   (Followers: 2)
Synthesis Lectures on Mathematics and Statistics     Full-text available via subscription   (Followers: 1)
Tamkang Journal of Mathematics     Open Access  
Tatra Mountains Mathematical Publications     Open Access  
Teaching Mathematics     Full-text available via subscription   (Followers: 10)
Teaching Mathematics and its Applications: An International Journal of the IMA     Hybrid Journal   (Followers: 4)
Teaching Statistics     Hybrid Journal   (Followers: 8)
Technometrics     Full-text available via subscription   (Followers: 8)
The Journal of Supercomputing     Hybrid Journal   (Followers: 1)
The Mathematica journal     Open Access  
The Mathematical Gazette     Full-text available via subscription   (Followers: 1)
The Mathematical Intelligencer     Hybrid Journal  
The Ramanujan Journal     Hybrid Journal  
The VLDB Journal     Hybrid Journal   (Followers: 2)
Theoretical and Mathematical Physics     Hybrid Journal   (Followers: 7)
Theory and Applications of Graphs     Open Access  
Topological Methods in Nonlinear Analysis     Full-text available via subscription  
Transactions of the London Mathematical Society     Open Access   (Followers: 1)
Transformation Groups     Hybrid Journal  
Turkish Journal of Mathematics     Open Access  
Ukrainian Mathematical Journal     Hybrid Journal  
Uniciencia     Open Access  
Uniform Distribution Theory     Open Access  
Unisda Journal of Mathematics and Computer Science     Open Access  
Unnes Journal of Mathematics     Open Access   (Followers: 1)
Unnes Journal of Mathematics Education     Open Access   (Followers: 2)
Unnes Journal of Mathematics Education Research     Open Access   (Followers: 1)
Ural Mathematical Journal     Open Access  
Vestnik Samarskogo Gosudarstvennogo Tekhnicheskogo Universiteta. Seriya Fiziko-Matematicheskie Nauki     Open Access  
Vestnik St. Petersburg University: Mathematics     Hybrid Journal  
VFAST Transactions on Mathematics     Open Access   (Followers: 1)
Vietnam Journal of Mathematics     Hybrid Journal  
Vinculum     Full-text available via subscription  
Visnyk of V. N. Karazin Kharkiv National University. Ser. Mathematics, Applied Mathematics and Mechanics     Open Access   (Followers: 2)
Water SA     Open Access   (Followers: 1)
Water Waves     Hybrid Journal  
Zamm-Zeitschrift Fuer Angewandte Mathematik Und Mechanik     Hybrid Journal   (Followers: 1)
ZDM     Hybrid Journal   (Followers: 2)
Zeitschrift für angewandte Mathematik und Physik     Hybrid Journal   (Followers: 2)
Zeitschrift fur Energiewirtschaft     Hybrid Journal  
Zetetike     Open Access  

  First | 1 2 3 4     

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Science Progress
Journal Prestige (SJR): 0.351
Citation Impact (citeScore): 1
Number of Followers: 1  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 0036-8504 - ISSN (Online) 2047-7163
Published by Sage Publications Homepage  [1174 journals]
  • Evaluation of lateral capacity for flexible drilled shafts in cohesionless
           soils

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      Authors: Ssu-An Chou, Yit-Jin Chen, Jiunn-Shyang Chiou, Anjerick Topacio, Maria Cecilia Marcos
      Abstract: Science Progress, Volume 105, Issue 3_suppl, July-September 2022.
      This study aimed to evaluate and improve the p–y curve method for use in the lateral analysis of flexible circular drilled shafts in cohesionless soils. Onsite circular drilled shaft lateral load test data from all over the world were collected, and the applicability of O’Neill and Murchison's p–y curve method was evaluated by comparing the measured values with the method's predicted values. Results showed that the current predictions were underestimated after applying the method to a database of flexible circular drilled shafts in cohesionless soils. Then, the difference (ΔQ) between the predicted value (Qp) and measured value (Qm) was normalized using the measured value (ΔQ/Qm) to determine the percent difference, and an average value of − 47% was produced. The difference ratio between the measured and predicted values was proportional to the diameter of the pile. To calibrate the prediction of the current method, this study applied two parameters (α and β) as modifications to reduce ΔQ. The parameters were decided by using the average difference ratio and average absolute difference methods. The reliability and consistency of the prediction of the p–y curve method were enhanced by applying the recommended modifying parameters. Specific design recommendations were also provided based on the proposed modifications on the original p–y curve.
      Citation: Science Progress
      PubDate: 2022-07-22T06:49:55Z
      DOI: 10.1177/00368504221113195
      Issue No: Vol. 105, No. 3_suppl (2022)
       
  • Does tourism industry agglomeration improve China's energy and carbon
           emissions performance'

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      Authors: Yicheng Zhou, Boqiang Lin
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      The tourism industry is seen as having great potential, but tourism development and tourism activities may increase energy consumption and environmental pressure. Based on the provincial panel data of China from 2000 to 2017, we calculate the energy and carbon emission performance by using the non-radial distance function (NDDF) and further investigate the impact of tourism industry agglomeration on energy and carbon emission efficiency by combining the panel fixed effect model, mediation effect model and quantile regression. Our research results show that there is an inverted U-shaped relationship between tourism industry agglomeration and energy and carbon emission efficiency, and tourism industry agglomeration can improve energy and carbon emission efficiency at present. At the same time, the impact of tourism industry agglomeration on energy and carbon emission efficiency has regional heterogeneity. The industrial structure upgrading plays an important role in the process of tourism industry agglomeration. In addition, with the improvement of energy and carbon emission performance, the impact of tourism industry agglomeration is also different. These findings suggest that policymakers should promote tourism industry agglomeration to realize energy conservation and emission reduction. The Chinese government should focus on the tourism resources and advantages of different regions and formulate differentiated regional policies to improve ecological performance.
      Citation: Science Progress
      PubDate: 2022-09-22T05:02:55Z
      DOI: 10.1177/00368504221126790
      Issue No: Vol. 105, No. 3 (2022)
       
  • Microplastics in soil and freshwater: Understanding sources, distribution,
           potential impacts, and regulations for management

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      Authors: Maimoona Raza, Jin-Yong Lee, Jihye Cha
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Plastic debris is a complex and persistent environmental contaminant that has received a high amount of attention in the last few years. Understanding the sources, transport, fate, occurrence, and health risks of microplastics (MPs) in the environment is essential as millions of tons of plastic are manufactured and released into the environment. There is a high possibility that MPs will accumulate and retain within continental environments and have effects on the environment and human health. This review elucidates the outcomes of studies related to the prevalence, transport, fate, and health risks of MPs in soil and freshwater environments. The review shows that the sources of MPs are diverse and extensive and their occurrence, transport, fate, and health risks in the environment are affected by their physico-chemical characteristics and by natural factors. Implemented legislation or regulatory plans to reduce MPs contamination of the environment have been reviewed in this study. Moreover, management options are presented.
      Citation: Science Progress
      PubDate: 2022-09-22T05:02:19Z
      DOI: 10.1177/00368504221126676
      Issue No: Vol. 105, No. 3 (2022)
       
  • Optimal design and numerical analysis of multi-field coupling in a screw
           pump under wet gas compression

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      Authors: Xuejing Zhang, Junhu Yang, Li Wang, Chong Ma, Wei Han, Yubing Gong
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      During on-site operation under wet gas compression, the volumetric efficiency of a twin-screw pump decreases sharply, the temperature in the pump rises significantly, severe vibration and even jamming can occur. To solve the problems caused by wet gas compression structurally, a method for optimizing the design of a decompression screw is proposed in this paper based on the characteristics of a twin-screw pump and screw compressor. A fluid–solid multi-field thermal-coupling scheme is used to calculate the pressure, temperature, deformation, outflow, and volumetric efficiency of a screw pump before and after optimization. The average deviation between the calculated outflow and the experimental results was no more than 5%, demonstrating the accuracy of the calculation. After optimization, the return flow between the pump stages was significantly reduced and the outflow had increased. When the pressure difference between the inlet and outlet was 1 MPa, the maximum increase was about 18%. With an increase of the gas volume fraction from 95% to 99%, the average increase of the volumetric efficiency was about 14%. The temperature rise in the chambers at all levels and the temperature difference between the inlet and outlet of the decompression screw pump were lower than those of a traditional screw pump. The deformations at the three clearances were also less than those of a traditional screw pump, which helps to avoid jamming caused by thermal expansion.
      Citation: Science Progress
      PubDate: 2022-09-17T05:05:06Z
      DOI: 10.1177/00368504221124955
      Issue No: Vol. 105, No. 3 (2022)
       
  • The economic and environmental analysis of solar energy development under
           climate impacts

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      Authors: Liguo Zhang, Qin Zhang, Muhammad Aftab Rafiq
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Solar energy is a promising renewable technology to secure energy security and reduce emissions. While there are several solar energy studies, the intensified climate change has altered the climate pattern such as regional sunny hours and the strength of solar radiation. To investigate the impact of climate change on the regional solar energy potential, this study analyses the average sunny hour and solar radiation from monthly data from Jan. 2009 to Apr. 2021 and applies the ARIMA and ARDL models to predict the potential changes of these factors for the period of May 2021 to Dec. 2025. The results show the impact of climate change on solar energy generation potential is geographically different. Based on the historical data, the estimated electricity generation potential from conventional PV, PV/PCM, and PVT/PCM technologies are 2,636, 2,747, and 2868 kWh per m2, respectively. However, under climate impacts, their power potential will be greatly reduced to 2,422, 2,525, and 2636 kWh per m2. Specifically, the future power potential will decline up to 8%, and thus the policymakers should incorporate the climate influence on solar energy development and application to minimize power fluctuation.
      Citation: Science Progress
      PubDate: 2022-09-15T06:28:13Z
      DOI: 10.1177/00368504221124065
      Issue No: Vol. 105, No. 3 (2022)
       
  • Effect of methomyl on water quality, growth performance and antioxidant
           system in liver of GIFT (Oreochromis niloticus) in the presence of
           peppermint (Mentha haplocalyx Briq.) as a floating bed

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      Authors: Xiaojun Jing, Tingyan Liu, Benkhelifa Fateh, Jiazhang Chen, Yao Zheng, Gangchun Xu
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      This study was conducted to investigate the effect of methomyl (MET) on water quality, growth and antioxidant system of genetically improved farmed tilapia (GIFT, Oreochromis niloticus) in the presence of peppermint as a floating bed. The concentration of NH3-N, NO2−-N, NO3−-N and TP in T3 (with 200 g wet peppermint) was significantly lower (P 
      Citation: Science Progress
      PubDate: 2022-09-14T05:15:48Z
      DOI: 10.1177/00368504221124047
      Issue No: Vol. 105, No. 3 (2022)
       
  • Ensemble of diverse deep neural networks with pseudo-labels for repayment
           prediction in social lending

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      Authors: Ji-Yoon Kim, Sung-Bae Cho
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      In peer-to-peer (P2P) social lending, it is important to predict the repayment of borrowers. P2P lending data are generated in real-time, but most of them are pending to decide the repayment because the deadline is not yet expired. Adding the unexpired data with appropriate labels into the training set could improve the performance of a prediction model, but the pseudo-labels cannot be certainly precise. In this paper, we propose an ensemble classifier composed of diverse convolutional neural networks (CNNs) of GoogLeNet, ResNet and DenseNet for the repayment prediction in social lending with the pseudo-labels approximated by an uncertainty handling scheme. The additional data labeled by Dempster-Shafer fusion of two semi-supervised learning methods boost up training of various models of CNNs, which are combined by weighted voting. A diversity measure is applied to constructing a pool of different models of CNNs that extract the effective features in the social lending data with labeling noise and predict the borrower's loan status. The experiment with the real dataset of 855,502 cases from Lending Club confirms that the diverse ensemble combined with weighted voting achieves the highest performance and outperforms conventional methods.
      Citation: Science Progress
      PubDate: 2022-09-13T03:04:38Z
      DOI: 10.1177/00368504221124004
      Issue No: Vol. 105, No. 3 (2022)
       
  • Impact of non-exercise activity thermogenesis on physical activity in
           patients with COPD

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      Authors: Toru Shirahata, Yuki Nishida, Hideaki Sato, Sanehiro Yogi, Tomoe Akagami, Makoto Nagata, Shigeho Tanaka, Hidetoshi Nakamura, Fuminori Katsukawa
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Physical inactivity is associated with comorbidities and mortality in chronic obstructive pulmonary disease (COPD) patients. Although non-exercise activity thermogenesis (NEAT) is important for evaluating the physical activity level (PAL) of patients with chronic diseases, it has not yet been assessed in COPD patients. This study included male patients with COPD (n = 28) and high risk for COPD (n = 8). Total energy expenditure (TEE) and basal metabolic rate (BMR) were measured using the doubly labeled water (DLW) method and indirect calorimetry, respectively. PAL was calculated as TEE/BMR, while the NEAT was obtained from a questionnaire. Physical activity was also assessed using an accelerometer. The total NEAT score was correlated with PAL (r = 0.534, P 
      Citation: Science Progress
      PubDate: 2022-09-09T11:52:38Z
      DOI: 10.1177/00368504221117064
      Issue No: Vol. 105, No. 3 (2022)
       
  • Investigation of inflammation-related parameters in patients with
           candidemia hospitalized in the intensive care unit: A retrospective cohort
           study

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      Authors: Burcu Tunay, Selda Aydin
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      BackgroundCandidemia is the most common invasive fungal disease in intensive care units (ICUs).ObjectiveWe aimed to investigate cases of candidemia infection developing in the ICU and factors associated with mortality due to this infection.Materials and MethodsThis is a retrospective study including patients admitted to a tertiary university hospital ICU between January 2012 and December 2020. Patients over 18 years of age who had candida growth in at least one blood culture taken from central or peripheral samples (>48 h after admission to the ICU) without concurrent growth were evaluated.ResultsThe study group consisted of 136 patients with candida. Eighty-seven (63.97%) patients were male, with a median age of 69.5 (59–76.5) years. The 7-day mortality rate was 35.29%, while the 30-day mortality rate was 69.11%. As a result of multiple logistic regression analysis, after adjusting for age and malignancy, high APACHE II score and low platelet-lymphocyte ratio (PLR) - were found to be significant factors in predicting both 7-day and 30-day mortality.ConclusionIn this study, PLR and APACHE II scores were shown to be independent predictors of mortality in patients with candidemia in the ICU.
      Citation: Science Progress
      PubDate: 2022-09-08T05:21:00Z
      DOI: 10.1177/00368504221124055
      Issue No: Vol. 105, No. 3 (2022)
       
  • Exploring ecosystem carbon storage change and scenario simulation in the
           Qiantang River source region of China

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      Authors: Ludan Cao, Fanbin Kong, Caiyao Xu
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      To explore the impact of land-use change on carbon storage, this study coupled the InVEST model and the FLUS model to analyse the spatial and temporal characteristics of carbon storage in the Qiantang River source region from 2000 to 2030. The carbon storage in the study area is evaluated which declined rapidly from 166.22 × 106 t in 2000 to 164.41 × 106 t in 2020, and the spatial distribution of carbon storage could be characterized by “the northwest and the southwest of region with higher, the east and the centre of the region with lower”. The carbon storage was simulated based on the historical trend development scenario, the food security scenario, and the ecological protection scenario. The carbon storage with the food security scenario could achieve 162.74 × 106 t in 2030. The carbon storage with the ecological protection scenario had an increase of 62.60 t/km2 compared to the historical natural tendency development. Interestingly, the food security scenario had the smallest carbon loss value which is about $1.39 × 109, and its net carbon storage value was the largest which is about $3.71 × 109. The results of this study could provide a scientific reference for the conservation of carbon storage and land use management for climate change and sustainable development. This paper also can lay the foundation for subsequent further studies such as artificial intelligence.
      Citation: Science Progress
      PubDate: 2022-09-05T06:28:23Z
      DOI: 10.1177/00368504221113186
      Issue No: Vol. 105, No. 3 (2022)
       
  • Optimization insulation thickness and reduction of CO2 emissions for pipes
           in all generation district heating networks

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      Authors: Meryem Terhan
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      District heating systems are provided solutions for the increasing energy problems in high-population cities. Energy costs go up depending on increasing heat loss in DHS's distribution network. Heat loss from the network consists of 5–20% of transferred energy, and this loss is higher than the other losses in the heating system. In the study, heat losses from the pipes such as supply-return pipes, hot water and circulation pipes into heat canals are investigated based on energy, exergy, economic and environmental. Optimum insulation thicknesses, energy savings, reduction of CO2 emissions, the first investment costs and payback periods of the pipes in the network of all-generation district heating systems are investigated by using Life Cycle Cost Analysis (LCCA) method for fuel types like natural gas, fuel oil and coal. Optimum insulation thicknesses are calculated for different nominal sizes of pipes and various insulation materials such as glass wool, and rock wool for the different climatic zones. According to the results of the study, the heat losses from pipes in the 4th generation DHS network are decreased between 38.19% and 33.33% from the warmest climate zone to the coldest climate zone according to the 3rd generation. Energy savings, reduction of CO2 emissions, payback periods and optimum insulation thickness values of supply and return pipes in the network are respectively changed between 7.80–98.86 $/m, 39.61–322.32 kg CO2/year, 0.028–0.38 years and 0.025–0.0105 m depending on various fuel types, insulation materials, nominal size pipes, climatic zones and all generation types.
      Citation: Science Progress
      PubDate: 2022-09-01T07:01:32Z
      DOI: 10.1177/00368504221122287
      Issue No: Vol. 105, No. 3 (2022)
       
  • Robustification of the state-space MRAC law for under-actuated systems via
           fuzzy-immunological computations

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      Authors: Omer Saleem, Mohsin Rizwan, Fahim Gohar Awan
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      This paper formulates an enhanced Model-Reference-Adaptive-Controller (MRAC) that is augmented with a fuzzy-immune adaptive regulator to strengthen the disturbance-attenuation capability of closed-loop under-actuated systems. The proposed scheme employs the conventional state-space MRAC and augments it with a pre-configured fuzzy-immune mechanism that acts as a superior regulator to dynamically modulate the adaptation gains of the Lyapunov gain-adjustment law. The immunological computations increase the controller's adaptability to flexibly manipulate the damping control effort under exogenous disturbances. The efficacy of the proposed Immune-MRAC law is comparatively analyzed under practical disturbance conditions by conducting real-time hardware experiments on the QNET rotary pendulum. The experimental outcomes validate the faster transient-recovery behavior and stronger damping effort of the proposed control law against the exogenous disturbances while preserving the system's asymptotic stability and control energy efficiency.
      Citation: Science Progress
      PubDate: 2022-08-30T07:05:20Z
      DOI: 10.1177/00368504221122291
      Issue No: Vol. 105, No. 3 (2022)
       
  • Genetic diversity and growth responses of Indonesian tomato (Solanum
           lycopersicum L.) genotypes under lead stress

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      Authors: Nurul Jadid, Chusnul Eka Safitri, Adillatul Lathiifatun Jannah, Wirdhatul Muslihatin, Kristanti Indah Purwani, Faisol Mas’ud
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Tomato (Solanum lycopersicum L.) is cultivated and consumed worldwide, including in Indonesia. It is used in the food, cosmetic, and pharmaceutical industries, due to its high content of carotenoid (lycopene) compounds that have antioxidant and anticancer activities. In Indonesia, although several cultivars of tomato are cultivated, including Opal, Permata, Mutiara, and Rewako, studies on their genetic information are limited. Unpredicted climate change as well as heavy metal contamination, especially Pb pollution, has threatened Indonesian food security. Therefore, our study aimed to analyze the genetic diversity of the four local tomatoes using random amplified polymorphic DNA (RAPD) markers and to determine the growth responses of several local tomato genotypes under Pb stress. In this study, morphological responses to Pb, including plant height and root length were observed. The RAPD analysis showed that Rewako and Permata were distinct, whereas Opal and Mutiara were closely related, possessing 81.8% similarity. Pb stress influenced plant height and root length in the four tomato genotypes, with each genotype exhibiting different morphological responses than others. However, the closely related Mutiara and Opal genotypes demonstrated similar responses to Pb stress to Permata and Rewako. Our study demonstrates that RAPD are sensitive and efficient for elucidating the genomic profile of the tomato genotypes. In addition, our results suggest that genetic variation among tomato genotypes might influence the morphological responses against Pb stress.
      Citation: Science Progress
      PubDate: 2022-08-25T04:48:31Z
      DOI: 10.1177/00368504221122364
      Issue No: Vol. 105, No. 3 (2022)
       
  • Long-lasting leukocytosis in patients with schizophrenia treated with
           clozapine after electroconvulsive therapy: ECT stabilizes white blood cell
           count

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      Authors: Kotaro Sugita, Yasuhiro Mori, Kousuke Kanemoto, Sotaro Sugita
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      IntroductionThe present study was conducted to investigate the possible hematologic impact of long-term electroconvulsive therapy (ECT) in patients with drug-resistant schizophrenia and receiving clozapine therapy.Subjects and MethodsIn this retrospective study, clinical charts of 57 hospitalized patients with schizophrenia who required clozapine therapy because of active psychotic symptoms resistant to other antipsychotics were examined. For 18 who underwent ECT, the first assessment was conducted at the end of that therapy (average two months after start, 7.68 sessions) and the second two months later. As for the 39 patients who did not undergo ECT, the first and second assessment points were at two and four months, respectively, after a randomly chosen time point.ResultsMultiple regression analysis revealed that modified ECT (m-ECT) (ß = 0.346, p = 0.005), gender (males showed greater increase) (ß = 0.273, p = 0.023), and disease duration (longer associated with greater increase) (ß = 0.258, p = 0.033) were correlated with a change in white blood cell (WBC) count (ΔR2 = 0.277, p 
      Citation: Science Progress
      PubDate: 2022-08-24T08:01:36Z
      DOI: 10.1177/00368504221117067
      Issue No: Vol. 105, No. 3 (2022)
       
  • When donor T cells attack: The curious case of liver transplant-associated
           acute graft-versus-host-disease

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      Authors: Max Deschner, Donald J. Bastin, Ziad Solh, Karen Bosma, Wael Haddara, Ping Yang, Robert Broadbent, Aaron Haig, Jonathan Keow, Mayur Brahmania, Anargyros Xenocostas, Uday Deotare
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Graft versus host disease is a rare but deadly complication of solid organ transplant. Clinical features of graft-versus-host-disease are non-specific, which may lead to delayed diagnosis as more common conditions including infections or drug reactions are considered. We describe a 54-year-old male patient who underwent liver transplantation for alcohol use disorder-related cirrhosis and developed acute graft-versus-host disease. Initial clinical presentation included dermatitis, bone marrow failure and enteritis. Results of skin biopsy and cytogenetic studies were consistent with liver transplant-associated acute graft-versus-host disease. The importance of this case is to highlight to transplant physicians and surgeons the challenges of diagnosing graft-versus-host-disease. In our case, pre-existing partnerships among the liver and hematopoietic stem cell transplant teams, transfusion medicine specialists, critical care specialists and facilitated timely communication relevant to confirming graft-versus-host disease. We propose an algorithm to assist in the workup of suspected graft-versus-host disease. Because this condition is characterized by high mortality, a high index of suspicion is imperative for prompt diagnosis and optimal management of the donor-recipient immune interaction when patients present with classic clinical features.
      Citation: Science Progress
      PubDate: 2022-08-18T06:53:33Z
      DOI: 10.1177/00368504221117070
      Issue No: Vol. 105, No. 3 (2022)
       
  • A comprehensive review of fault diagnosis and fault-tolerant control
           techniques for modular multi-level converters

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      Authors: Faizan Ahmad, Muhammad Adnan, Arslan Ahmed Amin, Muhammad Gufran Khan
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      BackgroundMany faults occur in the modular multi-level converters (MMCs), including unbalancing capacitor voltage, lower and upper arm unbalancing, the line to line voltage unbalancing, sensors and actuators fault, system fault, and sub-modules fault in high as well as medium voltage applications.IntroductionSeveral fault-tolerant approaches are presented to overcome these problems, such as active fault-tolerant control system (AFTCS), passive fault-tolerant control system (PFTCS), hybrid fault-tolerant control system (HFTCS), redundant system technique, special power circuit with the controller, and zero sequence voltage methods, which we will explain extensively in this article.MethodologyThis review emphasizes the types of faults in the MMCs and discusses the protection methods under failure conditions. The MMC is more popular in high voltage applications because it not only improves the quality of the grid but also has good harmonic performance in high power transmission. There is no need for any isolated dc sources to operate it. When faults are removed, the efficiency and reliability of the system will be increased.ResultsThis extensive explanation of the current literature on MMC fault diagnosis and control techniques will conclude which methods provide a more valuable solution. Finally, this paper discusses the best approach to reduce MMC faults and provides a future research direction to the readers.
      Citation: Science Progress
      PubDate: 2022-08-17T08:03:27Z
      DOI: 10.1177/00368504221118965
      Issue No: Vol. 105, No. 3 (2022)
       
  • The development of input-monitoring system on biofuel economics and social
           welfare analysis

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      Authors: Chih-Chun Kung, Binbo Zheng, Hailing Li, Shan-Shan Kung
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Biofuel production relies on stable supply of biomass which would be significantly influenced by climate-induced impacts. Since the actual agricultural outputs are relatively unpredictable in the face of uncertain environmental conditions and can only be realized in the harvest season, providing useful information regarding the stability of biomass supply to the downstream biofuel industry is crucial. This study firstly illustrates a theoretical framework to explore the resultant market equilibrium and optimal conditions of agricultural and bioenergy production in the face of highly uncertain environmental risks and then employs a two-stage stochastic programming model to investigate the optimal biofuel development and associated economic and environmental effects. The results show that total welfare may not always increase because the loss of other agricultural commodities induced by climate impacts may be greater than the gains received by biofuel production and emission reduction. This study provides insights into the area where artificial intelligence monitoring system can be implemented to analyze the input data associated with agricultural activities and help the biofuel industry to improve its production possibilities.
      Citation: Science Progress
      PubDate: 2022-08-17T08:03:07Z
      DOI: 10.1177/00368504221118350
      Issue No: Vol. 105, No. 3 (2022)
       
  • Optimization of the Beijing Economy-Energy-Emissions System 2021–2035: A
           Scenario Simulation Analysis Based on a System Dynamics Model

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      Authors: Anfeng Zhu, Daojuan Wang, Yinghan Chen, Zhengquan Guo
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      This paper constructs an Economy-Energy-Emissions (3E) System Dynamics Model using the megacity of Beijing, China, as an example, to estimate the effects of different policy scenarios (including three single-policy scenarios and four combined-policy scenarios) on the core variables of Beijing's 3E system from 2021 to 2035. The results suggest two main points. (1) Following the current development trend, the proportion of the GDP represented by the added value of advanced high-precision industries (Gao Jing Jian in Chinese) will only be 43% in 2035, implying a limited role in promoting economic growth. Despite effective control of total energy consumption, fossil energy's share of total consumption will reach 57% by 2035, hindering the process of making the energy consumption structure cleaner and leading to failure to achieve the targeted inflection point in CO2 emissions by 2025. PM2.5 control shows some successful results and will decrease to 19 μg/m3 in 2035. However, a gap compared to other world-class cities remains. (2) The implementation of a single policy for either industrial structure optimization, energy structure transformation, or emissions control cannot simultaneously meet the goal of high-quality coordinated development of Beijing's 3E system, whereas the comprehensive implementation of policies in all three dimensions is demonstrably effective.
      Citation: Science Progress
      PubDate: 2022-08-17T08:02:49Z
      DOI: 10.1177/00368504221118231
      Issue No: Vol. 105, No. 3 (2022)
       
  • Eco-friendly management of Parthenium hysterophorus

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      Authors: Fredrick Ojija
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      In sub-Saharan Africa, the invasive plant Parthenium hysterophorus (Parthenium) is threatening ecosystem integrity, biodiversity, and smallholder livelihoods. But, there is no single effective method of controlling it. Desmodium intortum, Lablab purpureus, and Medicago sativa were tested for their capacity to suppress Parthenium, as well as the allelopathic potential of Desmodium uncinatum leaf crude (DuLc) extract. While the study investigated the effect of DuLc extract concentrations on seed germination and seedling growth in laboratory, pot, field plot, it also assessed the effect of selected suppressive plants on Parthenium growth. It was found that high levels of DuLc concentrations and suppressive plants inhibited Parthenium germination and growth. When Parthenium was grown with suppressive plants, its growth was inhibited compared to when it was grown alone. When grown with all three test plants, the stem height and total fresh biomass of Parthenium seedlings were lowered by more than 60% and 59% in pots, and 40% and 45% in plots, respectively. Parthenium seed germination was decreased by 57% in plots, 60% in pots, and 73% in petri dishes at higher DuLc concentrations (i.e. 75% and 100%). Parthenium seedling stem heights were 36% (in plots) and 30% (in pots) shorter when sprayed with higher concentrations of DuLc. Overall, the findings of this study suggest that suppressive plants and those containing allelochemicals can be employed as a management tool to combat Parthenium invasion in sub-Saharan Africa, notably in Tanzania.
      Citation: Science Progress
      PubDate: 2022-08-08T07:27:50Z
      DOI: 10.1177/00368504221118234
      Issue No: Vol. 105, No. 3 (2022)
       
  • Design optimization of powered ankle prosthesis to reduce peak power
           requirement

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      Authors: Muhammad Bilal, Mohsin Rizwan, Hafiz Farhan Maqbool, Muhammad Ahsan, Ali Raza
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      The aim of the prosthetic devices is to replicate the able-bodied angle-torque profile of a healthy human during locomotion. A lightweight and energy-efficient ankle joint is able to lower the actuator peak power and/or energy consumption per gait cycle, while adequately fulfilling the profile matching constraints. This study presents the design optimization of the prosthetic ankle joint containing an elastic element and actuator coupled with a rigid triangular part. The dimensions of the ankle joint triangular part were optimized to minimize actuator peak power and maximize spring energy within its elastic limits. As a result of series simulation tests, at 1.1 and 1.6 m/s walking speeds, the simulation of dorsi/plantar flexion shows up to 78.8% and 66.98% reduction in motor peak power compared to a direct drive system, respectively. Low power ankle-prosthetic device that closely matches the angle-torque profile of a healthy human’s ankle, is one of the key parameters for the cost-effectiveness of lower limb prostheses.
      Citation: Science Progress
      PubDate: 2022-08-08T07:27:33Z
      DOI: 10.1177/00368504221117895
      Issue No: Vol. 105, No. 3 (2022)
       
  • Body Shape Questionnaire-34 (BSQ) and Functionality Appreciation Scale
           (FAS) - pertinent body image screening tools: Creation and validation of
           Polish language versions

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      Authors: Ida Yurtsever, Łukasz Matusiak, Marta Szepietowska, Chris Evans, Jacek C Szepietowski
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Objective:Body image is defined as the perception of one's own body. While positive body image has a positive impact on quality of life, self-dissatisfaction may lead to depression, anxiety and low self-esteem. Body image might be quantified and evaluated: relevant instruments include the Body Shape Questionnaire (BSQ) and the Functionality Appreciation Scale (FAS).This study was designed to translate and evaluate the psychometric properties of the Polish versions of these instruments.Methods:Translation (both forward and backward) from the original English versions of the questionnaires met international standards. Internal consistency and test-retest reliability are reported from 89 participants for the BSQ and 103 for the FAS. The participants also completed the Polish versions of the Body Image Quality of Life Inventory (BIQLI) and the Body Appreciation Scale-2 (BAS-2) to explore convergent validity.Results:Both, Polish versions of the BSQ and the FAS demonstrated good internal consistency and reproducibility. Convergent validity revealed a moderate relationship between the BSQ and the BIQLI scores, and a strong one between the FAS and the BAS-2 scores.Conclusion:Polish versions of both BSQ and FAS questionnaires showed sufficiently strong psychometric properties to support their use in clinical and research work with Polish speaking patients.
      Citation: Science Progress
      PubDate: 2022-08-05T07:14:18Z
      DOI: 10.1177/00368504221117068
      Issue No: Vol. 105, No. 3 (2022)
       
  • Corrigendum

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      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.

      Citation: Science Progress
      PubDate: 2022-08-03T04:41:40Z
      DOI: 10.1177/00368504221116685
      Issue No: Vol. 105, No. 3 (2022)
       
  • Temporal profile of angiogenesis and expression of extracellular
           matrix-related genes in rat brains following experimental intracerebral
           hemorrhage

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      Authors: A-Li Yang, Hua-Jun Zhou, Tao Tang, Jie-Kun Luo, Han-Jin Cui
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Background:Angiogenesis is essential for the repair process after intracerebral hemorrhage (ICH).Methods:Given the importance of the extracellular matrix (ECM) in angiogenesis, we analysed the temporal profile of angiogenesis in rat brains on days 4, 7, and 21 after ICH. To this end, we compared the expression of ECM-related genes between ICH-induced and sham-operated groups using a complementary DNA (cDNA) array. We further measured protein expression using western blot and immunohistochemistry assays. Fluorescein isothiocyanate (FITC)-dextran was injected into the tail vein to examine the angioarchitecture in the perihematomal region.Results:Among the 88 ECM-related genes, we identified 42, 50, and 38 genes that were significantly upregulated on days 4, 7, and 21 after ICH, respectively (P 
      Citation: Science Progress
      PubDate: 2022-07-28T06:14:25Z
      DOI: 10.1177/00368504221115509
      Issue No: Vol. 105, No. 3 (2022)
       
  • Oscillometry in total laryngectomized patients: A case study

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      Authors: Antonio Gilardi, Maria Carolina Colucci, Andrea Colizza, Mario Barreto, Antonio Minni, Massimo Ralli, Antonio Greco, Pasquale Parisi, Marco de Vincentiis
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Attempts to analyze respiratory function of the laryngectomized patient with tests such as spirometry and plethysmography have been described in the literature, highlighting however substantial difficulties. Oscillometry, through the forced oscillation technique (FOT), measures the mechanical properties of the respiratory system minimizing the problems related to the patient's lack of compliance. This methodology has never been applied to these patients and therefore represents a new perspective in the analysis of respiratory function.
      Citation: Science Progress
      PubDate: 2022-07-22T06:49:36Z
      DOI: 10.1177/00368504221110854
      Issue No: Vol. 105, No. 3 (2022)
       
  • Temporomandibular joint synovial chondromatosis: An analysis of 7 cases
           and literature review

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      Authors: Zhiqiang Song, Shanshan Yuan, Junjie Liu, Astrid D. Bakker, Jenneke Klein-Nulend, Janak L. Pathak, Qingbin Zhang
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Objective:To investigate the diagnosis and treatment procedure of synovial chondromatosis (SC) of the temporomandibular joint (TMJ).Methods:Clinical features, imaging features, surgical methods, and prognosis of 7 patients with SC of the TMJ were analyzed. We also reviewed and analyzed surgery-relevant literature included in the Pubmed database in the past decade using the search terms “synovial chondromatosis” and “temporomandibular joint”, and found 181 cases.Results:There was no specific difference in the symptoms of SC in the TMJ in different Milgram’s stages in our cases and the cases mentioned in the literature. The main symptoms of SC in the TMJ were pain (100%, 7/7; 64.64%, 117/181), limited mouth opening (57.14%, 4/7; 53.59%, 97/181), swelling (14.29%, 1/7; 28.18%, 51/181), crepitus (28.57%, 2/7; 19.34%, 35/181), and clicking (14.29%, 1/7; 9.94%, 18/181) in our cases and cases from literature separately. The imaging features of SC were occupying lesions (including loose bodies or masses) (71.42%, 5/7; 37.57%, 68/181), bone change in condyle or glenoid fossa (1/7, 14.29%; 34.81%, 63/181), effusion (42.86%, 3/7; 20.99%, 38/181), joint space changes (42.86%, 3/7; 11.05%, 20/181) in our cases and cases from literature separately. The surgical procedures seem to depend mainly on the involved structures and the extension of the lesion rather than the Milgram’s stage.Conclusions:The clinical features of SC in the TMJ are nonspecific and easy to be misdiagnosed. MRI is helpful in the diagnosis of SC in the TMJ. The surgical procedures mainly depend on the involved structures and the extension of the lesion.
      Citation: Science Progress
      PubDate: 2022-07-19T06:33:33Z
      DOI: 10.1177/00368504221115232
      Issue No: Vol. 105, No. 3 (2022)
       
  • Risk of device-related thrombosis following short-term oral
           anticoagulation with low-dose dabigatran versus warfarin after Watchman
           left atrial appendage occlusion

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      Authors: Heng Ge, Chi Zhang, Zhi-Qing Qiao, Zi-Yong Hao, Zheng Li, Zhi-Chun Gu, Li-Sheng Jiang, Ben He, Jun Pu
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Background:Percutaneous left atrial appendage occlusion (LAAO) provides an alternative for poor candidates for long-term oral anticoagulation (OAC). To prevent device-related thrombosis (DRT), OAC should be continued for the first 45 days to allow complete endothelialization post-LAAO implantation. Whereas, evidence is limited on the feasibility and safety of direct oral anticoagulants (DOACs) used after LAAO.Methods:This was a retrospective observational single-center study of AF patients undergoing LAAO with a Watchman device and receiving either low-dose dabigatran (110mg twice daily) or warfarin in the peri- and post-procedural period for 45 days. Transesophageal echocardiography was scheduled to perform at 6 weeks, 6 months, and 12 months after the procedure to assess the stability of the device and to detect DRT. Incidence of thromboembolic and bleeding events were also evaluated during the follow-up period.Results:There were a total of 84 patients who successfully underwent Watchman implantation, with 38 patients (45.2%) receiving low-dose dabigatran and 46 patients (54.8%) using warfarin post-LAAO. Peri-procedural complications occurred in 10 patients, with 3 patients in the dabigatran group and 7 patients in the warfarin group (7.9% vs. 15.2%, p = 0.30). During the 12-month follow-up, 1 patient experienced major bleeding and 16 patients suffered minor bleeding in the warfarin group, while 5 patients treated with dabigatran had minor bleeding (34.8% vs. 13.2%, p = 0.02). Besides, 6 DRT (15.8%) were detected in dabigatran groups, and the incidence was higher than in the warfarin group (15.8% vs. 2.2%, p = 0.03). No DRT-related ischemic events were found.Conclusions:This study suggested that short-term low-dose dabigatran (110 mg twice daily) could significantly decrease the risk of bleeding compared with warfarin at the expense of increased risk of DRT post-LAAO. Therefore, low-dose dabigatran should be used with caution for post-implant anticoagulation of LAAO. Further studies are urgently needed on the feasibility and safety of DOACs post-LAAO.
      Citation: Science Progress
      PubDate: 2022-07-18T03:54:49Z
      DOI: 10.1177/00368504221113194
      Issue No: Vol. 105, No. 3 (2022)
       
  • Optimization of doubly-fed induction generator (DFIG)based wind turbine to
           achieve maximum power generation with imperialist competitive algorithm
           (ICA)

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      Authors: Saade Abdalkareem Jasim, Rosario Mireya Romero Parra, Yasir Salam Karim, Ahmed B. Mahdi, Maria Jade Catalan Opulencia, Khusniddin Fakhriddinovich Uktamov, Ali Thaeer Hammid
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Today, due to the end of fossil fuels and efforts to reduce the use of renewable resources, wind energy is a suitable option for the production of electrical energy due to its high-power generation. To increase the output efficiency of wind turbines, maximum power point tracking techniques are required for wind turbine energy conversion systems. In this research, the maximum power point (MPPT) method for two-way fed wind turbine systems (DFIG) is presented. The performance of the induction generator is presented on both sides of the power and the values of this generator such as speed, torque, voltage, current and maximum power at the time of wind speed changes. The presented work is presented in two scenarios and the model is performed without the algorithm then, a maximum power point tracking method based on the Colonial Competition Algorithm (ICA) has been applied to estimate the power of the two power induction generators. According to the results, it can be said that in the scenario with the algorithm of generating electric power by the turbine, several times in the production state is 9 MW, which is the rate of the turbine's nominal power, while in another scenario, the power generated by the turbine is 85% of the power in the state with the algorithm.
      Citation: Science Progress
      PubDate: 2022-07-14T08:38:23Z
      DOI: 10.1177/00368504221113193
      Issue No: Vol. 105, No. 3 (2022)
       
  • Alterations of IL-1beta and TNF-alpha expression in RAW264.7 cell damage
           induced by two samples of PM2.5 with different compositions

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      Authors: Yizhen Lyu, Jieting Zhou, Jianjun Li, Jin Li, Guocheng Hu, Liyun Wang, Liang Wang, Jing Han, Dong Wang
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Fine particulate matter 2.5 (PM2.5) has been demonstrated by previous studies to be associated with cell damage. To explore the impact of the composition of PM2.5 on PM2.5-mediated inflammation, this study investigated the composition of PM2.5 collected during the wintertime indoor heating season and observed its inflammatory effect. Samples were collected during the heating season from December 5, 2017, to January 8, 2018, in Xi’an. Compositions of organic carbon (OC), elemental carbon (EC), and water-soluble ions were analysed. Two representative samples (sample 1 and 2) were selected with significant differences in compositions. They were configured into four concentrations (0.1 μg/mL, 1 μg/mL, 10 μg/mL, 20 μg/mL) and used as interventions on RAW264.7 cells for 4 h and 24 h separately. Cell viability was detected by CCK-8. Tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) gene and protein expression levels were detected by real-time quantitative real-time polymerase chain reaction (RT-qPCR) and western blotting. The results showed that the cell viability of sample 1 intervened cells at 4 h and 24 h was lower than that of sample 2. IL-1β gene in most PM2.5 intervention groups was lower than in the control group. Protein expression was higher at 4 h than at 24 h. In conclusion, PM2.5 components influence cell viability and expression of IL-1β and TNF-α, while high concentrations of NO3−, Cl−, Na+, K+, Mg2+, Ca2+, and others in the PM2.5 composition have a significant harmful effect.
      Citation: Science Progress
      PubDate: 2022-07-14T08:18:31Z
      DOI: 10.1177/00368504221113709
      Issue No: Vol. 105, No. 3 (2022)
       
  • Women, negative work-home interaction and stress: Impact of the second
           wave of the COVID-19 pandemic on spanish general and healthcare workers

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      Authors: Carmen Rodríguez-Domínguez, Sara Domínguez-Salas, Regina Allande-Cussó, Macarena Romero-Martín, Juan Gómez-Salgado, Carlos Ruiz-Frutos
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      The COVID-19 pandemic has come to stay, at least for a while. The initial bewilderment and restrictive measures have given way to the population's mental decay and increased stress on workers facing work and family demands in a difficult-to-manage situation. For this reason, this descriptive cross-sectional study sought to analyze stress levels in a sample of 263 general and healthcare workers (from 24 to 67 years of age) and their relationship with negative work-home interaction (WHI) and with gender in the second wave of contagions and deaths caused by the COVID-19 pandemic in Spain (October-December 2020). The results showed that having a higher level of WHI, the presence of work overload, health concerns, economic concerns, and lower-income were predictors of stress among these workers. Age and health-related occupations were contributing factors to work overload and health-related concerns. In addition, the relationship between being a woman and suffering from higher stress levels was mediated by income level, economic concern, and the WHI. Other variables such as having children or dependents, marital status, concern for the health of others, and teleworking were not associated with the stress levels detected in the sample. This research pays attention to the health state of workers beyond the initial stage of the pandemic, where most studies on this issue have concentrated. Thus, this study provides evidence of the uneven impact this crisis has on women and men, contributing to clarifying the relationship between gender, the WHI, and stress.
      Citation: Science Progress
      PubDate: 2022-07-14T08:17:52Z
      DOI: 10.1177/00368504221112751
      Issue No: Vol. 105, No. 3 (2022)
       
  • Integration of various protein similarities using random forest technique
           to infer augmented drug-protein matrix for enhancing drug-disease
           association prediction

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      Authors: Satanat Kitsiranuwat, Apichat Suratanee, Kitiporn Plaimas
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Identifying new therapeutic indications for existing drugs is a major challenge in drug repositioning. Most computational drug repositioning methods focus on known targets. Analyzing multiple aspects of various protein associations provides an opportunity to discover underlying drug-associated proteins that can be used to improve the performance of the drug repositioning approaches. In this study, machine learning models were developed based on the similarities of diversified biological features, including protein interaction, topological network, sequence alignment, and biological function to predict protein pairs associating with the same drugs. The crucial set of features was identified, and the high performances of protein pair predictions were achieved with an area under the curve (AUC) value of more than 93%. Based on drug chemical structures, the drug similarity levels of the promising protein pairs were used to quantify the inferred drug-associated proteins. Furthermore, these proteins were employed to establish an augmented drug-protein matrix to enhance the efficiency of three existing drug repositioning techniques: a similarity constrained matrix factorization for the drug-disease associations (SCMFDD), an ensemble meta-paths and singular value decomposition (EMP-SVD) model, and a topology similarity and singular value decomposition (TS-SVD) technique. The results showed that the augmented matrix helped to improve the performance up to 4% more in comparison to the original matrix for SCMFDD and EMP-SVD, and about 1% more for TS-SVD. In summary, inferring new protein pairs related to the same drugs increase the opportunity to reveal missing drug-associated proteins that are important for drug development via the drug repositioning technique.
      Citation: Science Progress
      PubDate: 2022-07-08T07:07:25Z
      DOI: 10.1177/00368504221109215
      Issue No: Vol. 105, No. 3 (2022)
       
  • Research on AGV trackless guidance technology based on the global vision

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      Authors: Zhaolun Zheng, Yujun Lu
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      With the change of manufacturing mode and the progress of science and technology, the traditional manufacturing industry has gradually developed to intelligent manufacturing and flexible manufacturing. To achieve factory transformation, Automatic Guided Vehicle (AGV) is indispensable. In this paper, an AGV trackless guidance technology based on global vision is proposed. Firstly, the global vision camera is used to obtain the image of the AGV driving area, and then the obstacle information and position information of the AGV are obtained by image processing technology. Secondly, the A* algorithm is used to intelligently plan the AGV driving path, and the wireless network communication is used to control the AGV driving according to the planned path. Experiments show that the method is feasible and has the advantages of high flexibility, high precision, low cost and strong expansibility, which is of great significance to the realization of intelligent warehouse and unmanned chemical plant.
      Citation: Science Progress
      PubDate: 2022-07-01T10:30:16Z
      DOI: 10.1177/00368504221103766
      Issue No: Vol. 105, No. 3 (2022)
       
  • Physiologic and pathophysiologic roles of AKAP12

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      Authors: Hui Li
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      A kinase anchoring protein (AKAP) 12 is a scaffolding protein that improves the specificity and efficiency of spatiotemporal signal through assembling intracellular signal proteins into a specific complex. AKAP12 is a negative mitogenic regulator that plays an important role in controlling cytoskeletal architecture, maintaining endothelial integrity, regulating glial function and forming blood-brain barrier (BBB) and blood retinal barrier (BRB). Moreover, elevated or reduced AKAP12 contributes to a variety of diseases. Complex connections between AKAP12 and various diseases including chronic liver diseases (CLDs), inflammatory diseases and a series of cancers will be tried to delineate in this paper. We first describe the expression, distribution and physiological function of AKAP12. Then we summarize the current knowledge of different connections between AKAP12 expression and various diseases. Some research groups have found paradoxical roles of AKAP12 in different diseases and further confirmation is needed. This paper aims to assess the role of AKAP12 in physiology and diseases to help lay the foundation for the design of small molecules for specific AKAP12 to correct the pathological signal defects.
      Citation: Science Progress
      PubDate: 2022-07-01T10:29:36Z
      DOI: 10.1177/00368504221109212
      Issue No: Vol. 105, No. 3 (2022)
       
  • Mortality and risk factors for COVID-19 in hemodialysis patients: A
           systematic review and meta-analysis

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      Authors: Pulin Li, Youhong Guan, Sijing Zhou, Enze Wang, Peng Sun, Guanghe Fei, Daxiong Zeng, Ran Wang
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Introduction: The present study systematically reviewed the clinical features and risk factors in patients undergoing maintenance hemodialysis (MHD) who also acquired coronavirus disease 2019 (COVID-19). More specifically, clinical manifestations, prognosis, and risk factors for death among this population were explored. Method: A literature search using the PubMed, Web of Science, and Embase databases, for articles involving patients with laboratory-confirmed COVID-19 and undergoing MHD published between January 1, 2020, and March 13, 2022, was performed. Random-effects meta-analyses were performed to calculate the weighted mean prevalence and corresponding 95% confidence interval (CI) or weighted means and 95% CI. Heterogeneity among studies was assessed using I2 statistics. Results: Twenty-two studies including 13,191 patients with COVID-19 undergoing MHD were selected. The most common symptoms included fever (53% [95% CI 41%–65%]) and cough (54% [95% CI 48%-60%]); however, 17% (95% CI 11%–22%) of the cases were asymptomatic. In subgroup analysis, the proportion of male patients (65% [95% CI 58%–71%]), and patients with coronary artery disease (30% [95% CI 17%–44%) and chronic obstructive pulmonary disease (9% [95% CI 4%–15%]) was greater in the non-survivor group compared with the survivor group. Furthermore, patients undergoing MHD, who were also positive for COVID-19, exhibited a high mortality rate (24% [95% CI 19%–28%]). Conclusions: MHD patients with COVID-19 may initially present as asymptomatic or with mild symptoms; nevertheless, in this study, these patients exhibited a higher risk for death compared with COVID-19 patients not undergoing MHD. Moreover, male sex and underlying cardiovascular and respiratory diseases increased the mortality risk.
      Citation: Science Progress
      PubDate: 2022-07-01T06:59:15Z
      DOI: 10.1177/00368504221110858
      Issue No: Vol. 105, No. 3 (2022)
       
  • Tooth root resorption: A review

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      Authors: Artak Heboyan, Anna Avetisyan, Mohmed Isaqali Karobari, Anand Marya, Zohaib Khurshid, Dinesh Rokaya, Muhammad Sohail Zafar, Gustavo Vicentis de Oliveira Fernandes
      Abstract: Science Progress, Volume 105, Issue 3, July-September 2022.
      Tooth root resorption is multifactorial, leading to progressive destruction and eventual loss of tooth root dentin and cement. There are internal and external types of root resorption, each having its variety. The etiology and pathogenesis of tooth root resorption are poorly understood, and the most significant etiological factors are trauma, pulpal infection, tooth bleaching, and orthodontic treatment. Tooth root resorption is primarily asymptomatic; thus, it is revealed accidentally by radiographic examination. Progressive clinical manifestations are pain, tooth discoloration, tooth mobility, and other conditions. Awareness of the causes and risk factors allowing tooth root resorption, and regular radiographic examination, in case of necessity, make it possible to reveal resorption at an early stage and to prevent its further development. Thus, the aim of this study is to present etiopathogenesis, a clinical course, and diagnostic peculiarities of internal and external types of tooth root resorption, enabling practicing dentists to timely diagnose root resorption and take appropriate measures to avoid further complications. Within the limitation of this review, even though the etiopathogenesis of tooth root resorption is yet not fully understood, it is suggested that the etiological factors fall into two groups (endogenic and exogenic) to enhance further understanding of the possible causes and mechanisms of root resorption and allow practitioners to monitor high-risk patients and make timely diagnoses. Moreover, radiographic examination and CBCT are indispensable for the diagnosis of root resorption.
      Citation: Science Progress
      PubDate: 2022-06-27T04:24:29Z
      DOI: 10.1177/00368504221109217
      Issue No: Vol. 105, No. 3 (2022)
       
 
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