 Subjects -> ALTERNATIVE MEDICINE (Total: 106 journals)
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- Cananga odorata Aromatherapy Reduces Anxiety in Unexperienced Patients
Hospitalized for Interventional Neuroradiology Procedures: A Randomized
Control Trial
Authors: Jetsada Sriboonlert, Waranon Munkong, Sunantha Rintawut, Soodjai Paladkhua, Ratchalita Suwongsa, Woranan Kirisattayakul
Abstract: Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023.
The hospitalization and the unfamiliar experiences of patients in interventional radiology procedures cause a moderate to high levels of anxiety. This study was aimed to evaluate the anxiolytic effect of Cananga odorata essential oil (COE) aromatherapy in unexperienced patients hospitalized for interventional neuroradiology (INR) procedures. Forty-four patients admitted for their first INR procedure were randomly divided into COE and placebo control groups. COE or distilled water was dropped onto 2 pieces of mulberry paper and attached to the participant's gown at the shoulder level overnight. The main outcomes were observed from the morning salivary cortisol levels and salivary alpha-amylase activity after intervention. The Thai version of Spielberger State-Trait Anxiety Inventory (STAI) and the vital signs (blood pressure and heart rate) were also assessed before and after COE intervention as the secondary outcome. The demographic and baseline data of both groups did not show any significant difference. After intervention, COE group had a significantly lower salivary alpha-amylase activity than placebo control group. The post-intervention scores of Trait (STAI-T) and State (STAI-S) anxiety were significantly less than those of baseline in both groups. Interestingly, the COE group had a greater percentage reduction on STAI-T after intervention than placebo control group. No significant difference was observed in other outcomes. In addition, the salivary alpha-amylase activity was weak but showed significant correlation with STAI anxiety scores. This study indicates that COE aromatherapy reduces the saliva alpha amylase activity and STAI-T anxiety in unexperienced patients hospitalized for INR procedures.
Citation: Journal of Evidence-Based Integrative Medicine
PubDate: 2023-01-20T06:02:18Z
DOI: 10.1177/2515690X221150527
Issue No: Vol. 28 (2023)
- Gymnema inodorum Leaf Extract Improves Cardiac Function in Experimental
Mice Infected with Plasmodium Berghei
Authors: Sakaewan Ounjaijean, Rujikorn Rattanatham, Voravuth Somsak, Worakan Boonhoh, Sirirat Surinkaew
Abstract: Journal of Evidence-Based Integrative Medicine, Volume 28, Issue , January-December 2023.
Malaria-associated cardiac injury has been reported to be the primary cause of death due to severe malaria. The discovery of substances showing a protective effect on cardiac injury during malaria infection is urgently needed. Hence, the purpose of this study was to evaluate the efficacy of Gymnema inodorum leaf extract (GIE) on cardiac function in mice infected with Plasmodium berghei. ICR mice were treated with 1 × 107 infected red blood cells of P. berghei ANKA (PbANKA), administered orally with GIE in 100, 250 and 500 mg/kg body weight of mice. Creatine phosphokinase (CPK) and echocardiography were carried out. It was found that CPK and heart-weight to body-weight (HW/BW) ratios were significantly higher in untreated mice than the healthy control. Moreover, impaired cardiac function in the untreated group was observed as indicated by changes in echocardiography. Interestingly, GIE exerted a protective effect on cardiac injury induced by PbANKA infection. Our results demonstrated that the parasitemia percentage, CPK, HW/BW ratio, and echocardiography in GIE treated mice were improved. However, there was no significant difference between GIE dosages. Therefore, GIE possessed a cardio-protective effect during malaria infection in mice.
Citation: Journal of Evidence-Based Integrative Medicine
PubDate: 2023-01-09T06:43:58Z
DOI: 10.1177/2515690X221150526
Issue No: Vol. 28 (2023)
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