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  Subjects -> VETERINARY SCIENCE (Total: 220 journals)
Showing 201 - 63 of 63 Journals sorted by number of followers
UK Vet Equine     Full-text available via subscription   (Followers: 7)
International Journal of Equine Science     Open Access   (Followers: 5)
Animal - Science Proceedings     Full-text available via subscription   (Followers: 5)
Agrivet : Jurnal Ilmu-Ilmu Pertanian dan Peternakan / Journal of Agricultural Sciences and Veteriner)     Open Access   (Followers: 3)
Journal of Veterinary Medical Research     Open Access   (Followers: 1)
Journal of Veterinary Forensic Sciences     Open Access   (Followers: 1)
Journal of Parasite Science     Open Access   (Followers: 1)
Austral Journal of Veterinary Sciences     Open Access   (Followers: 1)
International Journal of Veterinary Science and Research     Open Access   (Followers: 1)
Advances in Small Animal Care     Full-text available via subscription  
Archiva Zootehnica     Open Access  
Veterinary and Animal Science     Open Access  
Theoretical and Applied Veterinary Medicine     Open Access  
Journal of Veterinary Science & Medicine     Open Access  
Turkish Journal of Veterinary Research     Open Access  
EUREKA : Health Sciences     Open Access  
Revista Colombiana de Ciencia Animal     Open Access  
Iraqi Journal of Veterinary Sciences     Open Access  
AL-Qadisiyah Journal of Veterinary Medicine Sciences     Open Access  
Ukrainian Journal of Veterinary and Agricultural Sciences     Open Access  

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  • Molecular Phylogeny and Genetic Diversity of Interferon-α-A Domestic Yaks
           (Bos grunniens) in Pakistan

    • Authors: M. Ellahi Babar, T. Hussain, A. Ali, A. Aftab, M. Sohail, M. Ali, Q. ul-Ain, A. Wajid, M. Faizan, F. M. M. T. Marikar, M. M. Musthafa
      Pages: 3 - 7
      Abstract: Among the livestock species, wild yaks (Bos grunniens) survive only in the Tibetan region and Pakistan K2 region. They have declined dramatically in range and numbers and, therefore, were domesticated even in Pakistan due to the multipurpose function of the animal, which provides meat, milk, and other dairy products. Interferons were initially characterized for their ability to `interfere' with viral replication, slow cell proliferation, and profoundly alter immunity. They are a group of hormone-like molecules synthesized and secreted by macrophages, monocytes, T lymphocytes, glia, and neurons. For this purpose, Domestic yak blood 53 samples were collected from Gilgit and Bultistan and genotyped using a set of labeled microsatellite loci for this purpose. After PCR, DNA fragment sizes were determined in an ABI 3130 Genetic Analyzer. All microsatellite markers were successfully amplified and exhibited a polymorphic nature. Phylogenetic analysis based on the microsatellite DNA IFN-α-A of the control region (401 bp) showed nine microsatellite DNA haplogroups identified in Pakistani domestic Yaks. Phylogenetic analysis of the IFN-α-A gene suggested the domestic yak's sequences clustering into nine highly divergent maternal lineages. The current study analyzed the genetic variation and phylogenetic analysis of the IFN-α-A gene in the domestic yak, with comparisons to other IFN regions to investigate immune diversity levels and to design molecular selection strategies for better disease-resistant animals. It found nine clusters, and the implications of these findings can be utilized for yak conservation.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.01
      Issue No: Vol. 5, No. 2 (2022)
       
  • Study the effectiveness of using a complex of disinfectants and probiotics
           in the presence of poultry

    • Authors: O. M. Chechet, V. L. Kovalenko, O. I. Vishchur, O. S. Haidei, O. V. Krushelnytska, B. V. Gutyj
      Pages: 8 - 16
      Abstract: In the industrial production of broiler meat, optimal housing conditions are created to increase productivity and meat quality. To maintain the natural resistance of poultry, the technology of poultry must use probiotics and quality, safe disinfectants. This article deals with the discussion due to the research results on the integrated use of two probiotics and two disinfectants in raising broiler chickens. The scheme, modes, and terms of using probiotics and disinfectants for broiler chickens during their cultivation are offered. Doses and concentrations of the studied preparations are also generalized. The influence of the investigated preparations on hematological parameters, growth, and safety of poultry was analyzed. The results of the research showed that feeding with probiotics and disinfectants did not significantly influence the daily feed consumption of chickens but caused a 6.2 % increase in average daily gain and a decrease of 0.1 feed conversion rate in chickens of the experimental group. Production investigation has determined the modes of disinfection of poultry houses in the presence of broiler chickens when using a disinfectant, “Biolide”, based on hydrogen peroxide, lactic acid, and lactic acid. The bactericidal effect of disinfection of walls, floors, and feeding troughs of the premises with aerosol use of disinfectant “Biolide” and spraying of probiotic powder “Biozapin” 2 days after treatment, at the rate of 10‒30 g/m2 1 time in 2 weeks. There was an increase in the productivity of the studied poultry for feeding with probiotic feed “Biomagn” at the rate of 0.5 kg per ton of feed according to the scheme: from one day of age – seven consecutive days and 22 days of age – seven days in a row with constant water treated with disinfectant preparation “Diolide” based on chlorine dioxide, which made it possible to get quality products and cost-effective production. According to the research results, it is set that the optimal mode of aerosol disinfection of poultry houses in the presence of broiler chickens using 0.2 % disinfectant “Biolide” is 50 ml/m3 of the room at an exposure of 60 minutes. The safe and optimal concentration of the disinfectant “Diolide” during water treatment in the water supply system at a dose of 1.0 mg/l of chlorine dioxide corresponds to 0.0004 % concentration. The bactericidal effect of disinfecting the room's surface in the presence of poultry during its rearing after disinfection with the disinfectant “Biolide” and probiotic “Biozapin” was almost 100 %, which confirms its effectiveness. Under the action of the investigated preparations, a stimulating influence on the gas transport function of the blood of broiler chickens was revealed, especially in the older age of their rearing. In particular, at the age of 34 days, the concentration of hemoglobin was higher by 10.7 % (P < 0.05), and the number of erythrocytes at the age of 34 and 41 days – by 41.7 (P < 0.01) and 24.1 % (P < 0.01), respectively. At the same time, likely changes in the number of leukocytes and the ratio of their species in the blood of chickens of the experimental group concerning the control were not detected. These data indicate that aerosol treatment of premises in the presence of chickens is non-toxic and has no negative influence on the physiological state, confirmed by investigations of morphological indicators of poultry blood.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.02
      Issue No: Vol. 5, No. 2 (2022)
       
  • Blood indices and immune organs morphological structure of broiler
           chickens under the influence of different doses of probiotic feed
           additives

    • Authors: M. Zhyla, N. Shkodyak, O. Pyatnychko, G. Kotsyumbas, N. Lisova, O. Sobodosh, M. Shkil, E. Khmil
      Pages: 17 - 27
      Abstract: In the development of effective methods of prevention and treatment of poultry today, importance is given to probiotics based on microbial cultures, in particular, lactobacilli, bifidobacteria, yeast, etc. In contrast to antibiotics, the use of probiotics stimulates the immune response of animals, restores the microflora of the gastrointestinal tract, and ensures its optimal ratio. At the same time, livestock products remain safe for the consumer. The purpose of our work was to conduct comparative clinical trials of the efficiency of the probiotic feed additive Probion-forte in terms of productivity, blood indices, and histological structure of immune organs of chicken broilers during fattening. The clinical studies were carried out with broiler chickens of “Cobb-500” cross at the age of 2 days, which were formed into four groups (300 units in each one). In order to determine the efficiency of application, probiotic feed additives were given to chickens in different concentrations during the growing period, together with the main diet. The first group (1st) was given probiotic Probion-forte in the dose of 1 g/kg of feed, the second group (2nd) – Probion-forte in a dose of 0.5 g/kg, the third (3rd) one – a probiotic-analog “Bio plus 2B” in a dose of 0.4 g/kg; the forth (4th) group was a control group – chickens received an essential diet, without adding any feed additives. The compound feed was provided according to norms recommended for the cross “Cobb-500”, considering age. On the 15th, 30th, and 43rd day of the test, 20 units were selected for hematological, pathomorphological and microbiological tests. The productivity of birds of all studied groups was evaluated by the average daily gains, safety, feed conversion, and slaughter output. The stabilized with EDTA chicken blood was used for morphological studies, and blood serum – for biochemical and immunological studies. Comparative clinical studies have shown that adding to the main diet of broiler chickens probiotic feed additive Probion-forte at a dose of 0.5 and 1.0 g/kg throughout the growing period increases the safety and improves feed digestibility, and increases the bird’s European Efficiency Index. Based on the obtained hematological, biochemical, and immunological parameters of blood, it can be argued about the activating effect on the body of broiler chickens probiotic feed additives, namely the intensification of reanimation of free amino acids, which increases the content of the studied metabolites of lipid metabolism, which chickens use as energy and plastic material. Stimulating cellular and humoral protection, nonspecific resistance is established, confirmed by a high level of lysozyme activity in blood serum and significantly higher content of T- and B-lymphocytes, NK-cells, and γ-globulins. The macro- and microscopic structure of the studied immune organs is preserved in all groups of broiler chickens. Compared with the control group, morphometric examination in the immune organs of broiler chickens of the first and second groups revealed an increase in the area and density of lymphoid elements, an increase in the number of plasmablasts and plasma cells, much higher structural and functional capacity of cells, which was reflected at the ultrastructural level. The most significant difference was found in the 1st group of chickens fed with the feed additive Probion-forte at a dose of 1.0 g/kg of feed.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.03
      Issue No: Vol. 5, No. 2 (2022)
       
  • Screening of infection conditions for brain microvascular endothelial
           cells infected by Streptococcus suis

    • Authors: Mingcheng Liu, Oksana Kasianenko
      Pages: 28 - 31
      Abstract: Streptococcus suis is a pathogen that causes swine meningitis, sepsis, and other diseases. There are 34 serotypes, of which type 2 is the most pathogenic. During the infection process of Streptococcus suis, several major virulence factors are involved and play a different roles. Streptococcal meningitis is caused by the bacteria’s ability to cross the blood-brain barrier and enter the central nervous system. Therefore, studying the interaction between Streptococcus suis and cerebral microvascular endothelial cells will help reveal meningitis's pathogenic mechanism. When studying the interaction between bacteria and cells, the number of infected bacteria and the time of infection are very important. In this study, Streptococcus suis serotype two was made into bacteria liquid and counted. Then bacteria were used to infect mouse brain microvascular endothelial cells with different multiplicity of infection (1,10,100 and 200). Cells were harvested at six h, nine h,12h,18h, and 24h after infection. The total RNAs of harvested cells were extracted, and the concentration of RNA was detected. The OD260/OD280 was between 1.8~2.4, OD260/OD230 was 1.5~2.4, and the concentration was greater than 100ng/µL. Total RNAs were reverse transcribed to cDNAs used to perform quantitative PCR to detect the mRNA expression of IL-18, IL-1beta, IL-6, and IL-10. The results showed that each MOI group's mRNA expression is higher than the control group with different infection times. When the multiplicity of infection is at 1, each group's relative expression of cytokines reaches a peak at 18hrs after infection. When the multiplicity of infection is at 10, each group's relative expression of cytokines reaches a peak at 12hrs after infection. When the multiplicity of infection is at 100, the relative expression of cytokines reaches a peak at 12hrs after infection. When the multiplicity of infection is at 200, the relative expressions of each cytokine reach a peak at 6hrs after infection. Based on the mRNA relative expression of each cytokine under different conditions, the optimal multiplicity of infection was 100, and the optimal infection time was 12h. The result provides a basis for the study of the pathogenic mechanism of meningitis.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.04
      Issue No: Vol. 5, No. 2 (2022)
       
  • Erythron and protein system in piglets blood under stress influence

    • Authors: I. I. Kovalchuk, O. I. Slepokura, I. A. Kolomiiets, V. A. Кolotnytskiy, L. S. Garmata, P. I. Golovach, O. I. Kamratska
      Pages: 32 - 36
      Abstract: The article presents the results of research on the development of adaptive syndrome in the system of erythron and protein of piglets at the effects of weaning stress. After one (anesthetic stage) and seven days (beginning of G.Selle's resistance stage), after the echoing, the adaptation of the erythron system was shown by a decrease in the number of red blood cells on the contrary of increasing the mean corpuscular volume and hemoglobin indicating the inhibition of erythrocytosis with simultaneous macrocytosis, and a decrease in mean Corpuscular hemoglobin concentration for 14.0–13.0 % that indicated hypochromia. In these stressful periods, the catabolism of protein substrates was discovered, the redistribution of albumins between blood and tissues in the form of a decrease in the total protein content by 6.1–7.1 % due to albumin by 14.8–10.0 %, and the deficit of the humoral link of the immune response due to reduction of γ-globulins by 29.9–18.7 %. In the later stages of the resistance stage (after 20 and 60 days after weaning), there was a stabilization of erythrocytic indices and the development of anisocytosis in the form of an increase in red cell distribution width by 19.0 %, with a simultaneous decrease of 6.1 % of the total protein content, redistribution of its fractions in the side of the growth of γ-globulins by 18.4 %. A practical, prolonged way of preventing disorders in the erythron and protein of extramarital piglets was feeding the additive “Biovir”, which stimulated the intensity of oxidative-reducing processes and the exchange of proteins.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.05
      Issue No: Vol. 5, No. 2 (2022)
       
  • Peculiarities of physico-chemical condition of uterine vaginal mucus
           during estral cycle

    • Authors: H. V. Maksymyuk, V. M. Maksymyuk, H. M. Sedilo, O. I. Stadnytska, O. K. Onufrovych, Z. D. Vorobets, B. V. Gutyj
      Pages: 37 - 42
      Abstract: The primary aim of the work was to study the peculiarities of the influence of endogenous factors (products of inflammatory processes occurring in the tissues of female genitals) in the biological system of type “environment (uterine-vaginal mucus) – substance (water, organic and inorganic substances)” on the indicators of mass (g, mg) of its components. The results of the experiments indicate that their harmful effect changes the color and density of mucus released during estrus (UVM); reduces the parameters of the mass content of H2O and inorganic substances (IS), but increases – organic (OS). Under these circumstances, the distribution of the parameters of the mass of the components of the dry residue (DR, dried at 105 oC) of UVM of cows of the experimental group is presented in a row where the mass of ОS1 (burn at 520–530 oC) ˃IS ˃ОS2 (burn at 650 оС), but for control is another as well as mass of IS˃ОS1˃ОS2. This means that the harmful effects of inflammatory products on the genital tissues of females negatively affect the distribution of the mass of OS and IS in the system “environment-substance”.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.06
      Issue No: Vol. 5, No. 2 (2022)
       
  • Pharmacological studies of the veterinary medicinal product
           “Dibutalastin Ointment”

    • Authors: O. A. Katsaraba, R. M. Sachuk, B. V. Gutyj, T. A. Velesyk, M. L. Radzykhovskyi, P. V. Sharandak, V. O. Pepko
      Pages: 43 - 48
      Abstract: The study of pharmacological studies of the veterinary medicinal product for external use in the form of ointment – “Dibutalastin Ointment” is a mandatory stage of preclinical research of the drug, which is a new development of PP “Biopharm” and LLC “DEVIE”. In a scientific experiment on laboratory animals, it is possible to assess the drug's safety for different terms of use to determine the zone of toxic action and doses that do not cause harmful effects on health. Therefore, the work aimed to carry out pharmacological studies of the drug with methyl salicylate and dimethyl sulfoxide in the form of an ointment for treating European fallow deer, deer, dogs, and cats with mastitis, arthritis, myositis, and injuries of various origins. The toxicological characteristics of the studied ointment “Dibutalastin” based on methyl salicylate and dimethyl sulfoxide were studied in an "acute" study on warm-blooded animals. The average lethal dose (LD50) for intragastric administration could not be established, as the volume exceeded the permissible level. It was established that according to the “average lethal dose when entering the stomach” indicator, the veterinary medicinal product belongs to relatively non-toxic substances (toxicity class IV). The results of pharmacological studies indicate the absence of resorptive-toxic effects, sensitizing properties, and irritating effects on the mucous membranes of the eyes and skin. Pathomorphological studies of animal organs when studying the acute toxicity of the drug showed that the developed ointment with methyl salicylate and dimethyl sulfoxide does not cause pathological changes in internal organs. From the point of view of veterinary toxicology, this drug is safe. Further studies will be the next stage of pre-registration tests aimed at studying the embryotoxic effect of “Dibutalastin Ointment”, which is mandatory material of the “Safety and residue studies” section of the dossier for this medicinal product.
      PubDate: 2022-10-06
      DOI: 10.32718/ujvas5-2.07
      Issue No: Vol. 5, No. 2 (2022)
       
 
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