Authors:Suman Mahmood, Sammyia Jannat, Asad Hussain Shah, Anila Fariq, Sajida Rasheed, Akhlaaq Wazeer, Saleh H. Salmen, Mohammad Javed Ansari, Abdul Qayyum Pages: 54 - 62 Abstract: Mycobacterium tuberculosis (Mtb) is a persistent threat to human life and a challenge to global public health. The pathogen’s antibiotic resistance has become a serious problem, prompting the development of nanotechnology-based medicines to prevent multidrug resistance in microorganisms. The present study aimed to synthesize silver nanoparticles (AgNPs), using leaves extracts of Achillea millefolium, Artemisia campestris and Hedera nepalensis to analyze their antimycobacterial potential. The biosynthesized silver nanoparticlesnwere harvested and characterized through UV visible spectroscopy,nField Emission Scanning Electron Microscopy (FESEM) and Energy Dispersive X-ray spectroscopy (EDX). The FESEM analysis showed, that selected plant-based silver nanoparticles were spherical in shape with a diameter ranging from 50 nm to 80 nm. Energy Dispersive X-ray spectroscopy revealed that constitute elements of silver nanoparticles are Ag, C, O, Cl and Ca. The biosynthesized AgNPs exhibited significant antibacterial potential against Mycobacterium tuberculosis. At a concentration of 50 μL Hedera nepalensis exhibited the highest growth inhibition at 97.33%, followed by Artemisia at 95%, whereas the percentage growth inhibition of Achillea millefolium at 50 μL concentration was 72.33% as compared to the Rifampicin (RIF) i.e., 40%. Fluorescence microscopy confirmed visible growth inhibition in both experimental and controlled cultures. Hedra nepalensis and Artemisia campestris showed promising potential to inhibit the growth of mycobacteria populations, indicating their potential for the development of novel nanomedicine to treat tuberculosis effectively. PubDate: 2024-04-16 DOI: 10.5073/JABFQ.2024.097.007 Issue No:Vol. 97 (2024)
Authors:Tan Viet Pham, Le Pham Tan Quoc, My Phuong Nguyen, Hong Ngoc Nguyen, Quoc Hung Nguyen, Thanh Tho Le, Van Hop Nguyen, Hong Thien Van Pages: 79 - 86 Abstract: Conamomum vietnamense is an endemic and rare species from Vietnam. The aim of this study is to determine the chemical compositions, antibacterial and antioxidant properties of the acetone extracts obtained from the different organs of this species for the first time. A total of 82 components were identified from the acetone extracts of leaf, flower, and rhizome of C. vietnamense using Gas chromatography–mass spectrometry (GC/MS) technique. Furthermore, the agar disk-diffusion method was also used to determine the antibacterial activity of the C. vietnamense extracts. Accordingly, the leaf extract was found to be effective against eight out of nine bacterial strains while the flower and rhizome extracts displayed activity against four out of nine tested bacteria. In addition, the three organs of C. vietnamense also possessed the high DPPH scavenging properties. The results of this study indicate that C. vietnamense extracts have the potential to be developed into pharmaceutical products in the future. PubDate: 2024-07-11 DOI: 10.5073/JABFQ.2024.097.010 Issue No:Vol. 97 (2024)
Authors:Mahdi Yahyazadeh, Mahshid Rahimifard, Najmeh Hadi, Zahra Shirazi, Samaneh Asadi-sanam, Razieh Azimi, Yousef Ajani, Maryam Makizadeh, Aiuob Moradi, Mahmood Bidarlord, Mozhgan Larti, Hamideh Fakhr-ranjbari, Negar Valizadeh, Taiebeh Amini, Dirk Selmar Pages: 87 - 91 Abstract: This paper aims to contribute reliable information to promote the pharmacological utilization of Papaver bracteatum by analyzing its wild population in Iran. For this purpose, 27 Iranian poppy specimens from 7 provinces of Iran were analyzed. The highest thebaine concentrations were detected in the capsules, whereas they were relatively lower in the flowering stems. Maximal concentration (more than 53 mg/g d.w.) was present in the P. bracteatum plant capsules growing in the Zanus region of Mazandaran province. Surprisingly, the thebaine concentration varies drastically excessively among the tested specimens, ranging from 5 to more than 53 mg/g d.w. Up to now, it is not known whether these drastic differences are due to clonal variations or the differences in the growth conditions, e.g., due to different stress levels of the plants. There is no doubt that the Iranian poppy represents an important alternative source for thebaine, yet, further studies and research are required to promote the farming of this auspicious pharmaceutical plant. In this context, it is of special interest to elucidate the effects of potential genotypes, the impact of the growing conditions as well as seasonal effects. PubDate: 2024-07-11 DOI: 10.5073/JABFQ.2024.097.011 Issue No:Vol. 97 (2024)
Authors:Samuel Elolu, Nadja Förster, Anne Kathrin Baier, Arnold Mathew Opiyo, Susanne Huyskens-Keil Pages: 92 - 101 Abstract: Amaranth leaves are rich in micronutrients and health-promoting secondary metabolites, but highly perishable. The effect of osmodehydration and drying on nutritional quality, health-promoting compounds and their postharvest preservation in Amaranthus cruentus leaves was investigated. The experimental set up consisted of four treatment variants with different levels of osmotic solution (NaCl) concentration, temperature and immersion time, i.e.; variant 1 (2.5%, 20 °C, 60 min), variant 2 (10%, 20°C, 60 min), variant 3 (10%, 40°C, 60 min), and variant 4 (10%, 40°C, 180 min). Osmodehydrated leaves were oven-dried at 30°C or 60°C, freeze-dried or stored at ambient temperature for 3 days, with non-osmodehydrated leaves as control. Results showed that proteins,minerals (Ca, Mg, Fe, Zn), carotenoids, flavonoids, and phenolic acids were preserved in osmodehydrated leaves with no significant changes, except proteins in freeze-dried and a significantly decreased chlorophyll content in both freeze- and oven-dried leaves of variant 4, corresponding to higher osmotic solution concentration, temperature and longer immersion time. During shelf-life, most nutrients and secondary metabolites were maintained with no significant changes, except protein that significantly increased while ascorbic acid and chlorophylls in both osmodehydrated and control leaves significantly decreased. Lower-temperature and shorter-time immersion resulted in better quality preservation. PubDate: 2024-08-07 DOI: 10.5073/JABFQ.2024.097.012 Issue No:Vol. 97 (2024)
Authors:Seham M. Hamed, Naayem M. El-Gaml, Marwa Y. A. Mohamed, Khaled A. H. Shaban, Abeer S. Aloufi, Shereen M. Korany, Abdullah A. Saber Saber Pages: 115 - 126 Abstract: Soil fertility and crop productivity in the Nile Delta are severely threatened by soil salinization. Hence, the development of reliable techniques to enhance the salinity tolerance of plants is an essential prerequisite for the desirable sustainable agricultural development in Egypt. In the present study, we evaluated the influence of seeds priming using a magnetic field (MF) at different exposure times (0, 15, 30, and 45 min), either alone or combined with seeds pre-soaking or foliar spraying with seaweed extracts of Hydroclathrus clathratus and Acanthophora spicifera. The effects on soil properties, growth, yield, and seed quality of Vicia faba grown in saline soil were assessed. Results indicated that MF-treated seeds (MFTS), either alone or coupled with seaweed treatments, distinctly improved soil characterization by decreasing EC and pH niches, and also increased the availability of soil macro- and micronutrient elements, particularly at MF long exposure time (≥30 min). MFTS and/or MFTS with seaweed treatments at 30 min improved soil fertility indices (CO2 evolution and nitrogenase activity) and induced the highest increases of macro- and micro-nutrient contents in seeds, plant growth and seed quality. Additionally, enhancement of chlorophyll a and b, carbohydrates and amino acids, and decreasing proline levels were the bases of salinity stress alleviation. Conclusively, seed priming in the MF coupled with foliar spraying of seaweed extracts could be a sustainable and affordable approach for cultivating V. faba plants under salinity stress conditions. PubDate: 2024-08-07 DOI: 10.5073/JABFQ.2024.097.014 Issue No:Vol. 97 (2024)
Open Access journal
[6 journals]
