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Food & Function
Journal Prestige (SJR): 1.209  Citation Impact (citeScore): 4 Number of Followers: 6  Hybrid journal (It can contain Open Access articles)ISSN (Print) 2042-6496 - ISSN (Online) 2042-650X Published by RSC  [50 journals]
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- Cow’s milk αS1- casein is more sensitizing than goat’s milk αS1-
casein in mouse model-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO01136K, PaperKai Zhang, Lina Zhang, Ruo ya Zhou, Jin jing Zhong, Kui Xie, Yan mei Hou, Peng Zhou
The aim of this study was to compare the sensitization of αS1-CN in cow and goat’s milk in a mouse model. Fifty mice were divided into Control group, adjuvant control...
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- Chimonanthus salicifolius attenuated vascular remodeling by alleviating
endoplasmic reticulum stress in spontaneously hypertensive rat-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04381A, PaperXiaoqin Zhang, Cuiping Xu, Bingfeng Lin, Xuehui Deng, Jiazhen Zhu, Xinyi Chen, Shuang Liu, Rui Li, Nani Wang, Liping Chen
Chimonanthus salicifolius (CS), the leaves of Chimonanthus salicifolius S. Y. Hu., is an effective tea to prevent and treat hypertension in China. This study aimed to explore the effect and...
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- Anti-osteoporosis effects and regulatory mechanism of Lindera aggregata
based on network pharmacology and experimental validation-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00952H, PaperFurong Wang, Pengze Rong, Juan Wang, Xiao Yu, Na Wang, Shengyu Wang, Zikai Xue, Junnan Chen, Wenlong Meng, Xin Peng
Osteoporosis (OP) is characterized by flaccidity of bones or bone bi-disease caused by kidney deficiency. Lindera aggregate has been used to strengthen the kidney function in China for thousands of...
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- Antiobesity drug-likeness properties and pancreatic lipase inhibition of a
novel low molecular weight lutein oxidized product, LOP6-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04064B, PaperNagashree Shamarao, Mukunda Chethankumar
Elevated expression of peroxisome proliferator-activated receptor-gamma (PPAR-), a key regulator of adipogenesis leads to lipid accumulation and obesity. Although orlistat is effective to improve obesity, flatus with discharge, faecal urgency,...
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- 20(S)-protopanaxadiol decreases atherosclerosis in the ApoE KO mice by
increasing the levels of LDLR and inhibiting its binding with PCSK9-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00392A, PaperYe-Wei Huang, Meng Zhang, Litian Wang, Yan Nie, JinBo Yang, Wen Luer Meng, Xuanjun Wang, Jun Sheng
Chinese medicinal and edible plants such as Panax notoginseng and ginseng are widely used for the treatment of Atherosclerosis (AS). AS is the main pathological basis of cardiac-cerebral vascular disease,...
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- FADS1 overexpression promotes fatty acid synthesis and triacylglycerol
accumulation via inhibiting the AMPK/SREBP1 pathway in goat mammary
epithelial cells-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00246A, PaperJiangtao Huang, Yuexin Shao, Xueyang Zong, Huawen Zhang, Xian Zhang, Zhifei Zhang, Huaiping Shi
During lactation, FADS1 is up-regulated, then inhibits the phosphorylation of AMPK. The downregulation of p-AMPK promotes SREBP1 nuclear translocation, and induces SREBP1 target gene FASN and ACC expression in GMEC, leading to increased lipogenesis.
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- Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in
mice with dysbiosis induced by antibiotics-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00287F, PaperAndrea Bellés, Diego Aguirre-Ramírez, Inés Abad, Marcos Parras-Moltó, Lourdes Sánchez, Laura Grasa
In situations of intestinal dysbiosis caused by taking antibiotics, lactoferrin, a bovine milk protein, improves intestinal health by modulating the intestinal microbiota and the immune system positively and can be used in functional foods.
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- Leafy vegetables fortification enhanced the nutritional profile and
reduced the glycemic index of yellow cassava pasta-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00072E, Paper
Open Access 
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Oluranti Lawal, Vincenzo Fogliano, Imke Rotte, Mattijs Dekker, Tayo Nathaniel Fagbemi, A. R. Linnemann
Food-to-food fortification of yellow cassava flour with leafy vegetable powders (Amaranthus and Telfairia occidentalis) was employed in this study to develop cassava-vegetable spaghetti-like pasta products (YP, YPA5, YPA10, YPU5, YPU10,...
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- An insight into an intriguing oxidative biotransformation pathway of
5-O-caffeoylquinic acid by a gut bacterium-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04304H, Paper Open Access 
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Gentiana Balaj, Zohreh Tamanai-Shacoori, Damien Olivier-Jimenez, Aurélie Sauvager, Milcard Faustin, Latifa BOUSARGHIN, Sandrine Le Gall - David, Sylvain Guyot, Dashnor Nebija, Sophie Tomasi, Marie Laurence Abasq
Microbiota is known to play a pivotal role to generate bioavailable and bioactive low molecular weight metabolites from dietary polyphenols. 5-O-caffeoylquinic acid (5-CQA), one of the main polyphenols found in...
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- Mycelium polysaccharides of Macrolepiota procera alleviate reproductive
impairments induced by nonylphenol-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00680D, PaperWenshuai Wang, Xiaoxu Li, Yaohan Zhang, Jianjun Zhang, Le Jia
Mycelium polysaccharides of Macrolepiota procera (MMP) had positive role in amelioration of NP-induced reproductive disorders.
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- Structural characterization of Poria cocos oligosaccharides and their
effects on hepatic metabolome in high-fat diet-fed mice-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00638C, PaperLin Zhu, Guangming Chen, Yanlei Guo, junping zheng, Huabing Yang, Xiongjie Sun, Yang Liu, Baifei Hu, Hongtao Liu
In this study, novel Poria cocos oligosaccharides (PCO) were prepared by enzymatic degradation, and their polymerization degree was determined to be 2−6 by LC-MS analysis. By monosaccharide composition analysis, methylation...
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- Chitosan oligosaccharides exert neuroprotective effects via modulating the
PI3K/Akt/Bcl-2 pathway in a Parkinsonian model-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04374A, PaperBin Wang, Ling Wang, Yufei Qu, Jingyu Lu, Wenshui Xia
Chitosan oligosaccharides relieve motor deficits in Parkinson's disease mice exposed to the neurotoxin MPTP.
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- Co-interventions with Clostridium butyricum and soluble dietary fiber
targeting the gut microbiota improve MAFLD via the Acly/Nrf2/NF-κB
signaling pathway-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04224F, PaperJunwei Shao, Tiantian Ge, Yingliang Wei, Yuhan Zhou, Mengyuan Shi, Huiyuan Liu, Zhi Chen, Yang Xia
Mechanisms of co-intervention with Clostridium butyricum and soluble dietary fiber to improve MAFLD.
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- Ganoderic acid A from Ganoderma lucidum protects against alcoholic liver
injury through ameliorating the lipid metabolism and modulating the
intestinal microbial composition-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03219D, PaperXu-Cong Lv, Qi Wu, Ying-Jia Cao, Yi-Chen Lin, Wei-Ling Guo, Ping-Fan Rao, Yan-Yan Zhang, You-Ting Chen, Lian-Zhong Ai, Li Ni
The beneficial effects of Ganoderic acid A (GAA) from Ganoderma lucidum on alcoholic liver injury and intestinal microbial disorder in mice exposed to excessive alcohol intake.
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- The Impact of Prebiotic Fructooligosaccharides on Gut Dysbiosis and
Inflammation in Obesity and Diabetes Related Kidney Disease-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04428A, Review ArticleNattavadee Pengrattanachot, Laongdao Thongnak, Anusorn Lungkaphin
Obesity is an extensive health problem worldwide that is frequently associated with diabetes. It is a risk factor for the development of several diseases including diabetic nephropathy. Recent studies have...
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- Preventive effect of Chinese dwarf cherry [Cerasus humilis (Bge.) Sok.]
fermentation juice on dextran sulfate sodium-induced ulcerative colitis
rats through the regulation of IgA and the intestinal immune barrier-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04218A, PaperBeibei Ran, Chang-E. Guo, Yushi Zhang, Chao Han, Tianli Cao, Houyu Huang, Zeyu Geng, Weidong Li
Ulcerative colitis (UC) is a modern, refractory disease, and studies have shown that UC is closely associated with the gut microbiota and intestinal immune barrier.
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- Unveiling the Phytochemical Nature of Acorns: The Relevance of Dehusking
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04043J, PaperLuís Castro, Tânia Ribeiro, Elisabete Alexandre, Jorge A. Saraiva, Manuela Pintado
Acorns are an abundant but despised fruit in Portugal. To better explore this natural resource, the effect of two different dehusking methods (thermal dehusking and dehusking by drying) on the...
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- Cinnamaldehyde Decreases the Invasion and u-PA Expression of Osteosarcoma
by Down-regulating FAK Signalling Pathway-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00634K, PaperShu-Chen Chu, Yih-Shou Hsieh, Li-Sung Hsu, Chin-Yin Lin, Yi-An Lai, Pei-Ni Chen
Cancer metastasis is the major cause of the high mortality risk of patients with osteosarcoma. Cinnamaldehyde has been shown to exhibit multiple tumour-suppressing activities, but its role in human osteosarcoma...
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- Study on the physicochemical properties and immunomodulatory anti-tumor
effect of the Pholiota adiposa polysaccharide-
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Abstract:Food Funct., 2022, 13,5153-5165
DOI : 10.1039/D1FO03628A, PaperZhongwei Yang, Zijing Liu, Jie Xu, Junmo Zhu, Youwei Pu, Yixi Bao
In this study, the extraction, purification, physical and chemical properties, and biological activity of the Pholiota adiposa (PAP) polysaccharide were investigated.
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- Oral processing behaviours of liquid, solid and composite foods are
primarily driven by texture, mechanical and lubrication properties rather
than by taste intensity-
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Abstract:Food Funct., 2022, 13,5011-5022
DOI : 10.1039/D2FO00300G, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Karina Gonzalez-Estanol, Maddalena Libardi, Franco Biasioli, Markus Stieger
The aim of the study was to understand the effect of saltiness and sweetness intensity on oral processing behaviours of liquid, solid and composite foods using a HUT test.
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- p-Synephrine suppresses inflammatory responses in
lipopolysaccharide-stimulated RAW264.7 cells and alleviates systemic
inflammatory response syndrome in mice-
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Abstract:Food Funct., 2022, 13,5229-5239
DOI : 10.1039/D2FO00299J, PaperMomoko Ishida, Chihiro Takekuni, Kosuke Nishi, Takuya Sugahara
We found that p-synephrine inhibits the production of proinflammatory cytokines in LPS-stimulated RAW264.7 cells. This inhibitory effect could be attributed to the downregulation of p38 MAPK and NF-κB cascades mediated by β-adrenergic receptors.
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- Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced
metabolic dysfunction-
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Abstract:Food Funct., 2022, 13,5023-5036
DOI : 10.1039/D2FO00060A, PaperTingwei Wang, Yongli Ye, Jian Ji, Shuang Zhang, Xingxing Yang, Jiayuan Xu, Jia-Sheng Wang, Zhiyuan Chen, Bangen Xia, Hongfang Shen, Ruowei Xia, Wenqin Shi, Xiulan Sun
Astilbin caused a significant improvement in lipid metabolism in HFD-fed mice. Astilbin could reduce weight gainand insulin resistance in obese individuals and modify intestinal microbiota disorders, lipid metabolism, and xanthine metabolism.
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- Underlying evidence for the health benefits of fermented foods in humans
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Abstract:Food Funct., 2022, 13,4804-4824
DOI : 10.1039/D1FO03989J, Review ArticleF. Rul, C. Béra-Maillet, M. C. Champomier-Vergès, K. E. El-Mecherfi, B. Foligné, M. C. Michalski, D. Milenkovic, I. Savary-Auzeloux
Fermented foods (FFs) have been a part of our diets for millennia and comprise highly diverse products obtained from plants and animals all over the world: Mechanisms of action and impact of health status.
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- Three urban areas of China: a cohort study of maternal–infant factors
and HM protein components-
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Abstract:Food Funct., 2022, 13,5202-5214
DOI : 10.1039/D1FO04123A, PaperJingyao Chen, Yan Liu, Junying Zhao, Tiemin Jiang, Tao Xu, Bin Liu, Yanpin Liu, Baoyu Yang, Ying Li, Xiaomei Zhang, Juncai Hou, Lijun Chen
This work studies the concentrations of proteins in human milk (HM) at different lactation periods and explores the influence of maternal–infant factors on the dynamics of HM proteins in a Chinese cohort.
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- Changes in the serum metabolomic profiles of subjects with NAFLD in
response to n-3 PUFAs and phytosterol ester: a double-blind randomized
controlled trial-
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Abstract:Food Funct., 2022, 13,5189-5201
DOI : 10.1039/D1FO03921K, PaperXinwen Ding, Yinfei Xu, Pan Nie, Lingyue Zhong, Lei Feng, Qi Guan, Lihua Song
Co-supplementation of n-3 PUFAs and PSE significantly increased the serum levels of PUFA-containing phosphatidylcholine (PC), lysophosphatidylcholine (LysoPC), and some of these metabolites correlated negatively with the degree of hepatic steatosis.
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- Vitamin C enhances the ex vivo proliferation of porcine muscle stem cells
for cultured meat production-
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Abstract:Food Funct., 2022, 13,5089-5101
DOI : 10.1039/D1FO04340D, PaperJiahua Fang, Mei Li, Guoqiang Zhang, Guocheng Du, Jingwen Zhou, Xin Guan, Jian Chen
VC stimulated porcine muscle stem cell proliferation by activating the PI3K/AKT/mTOR pathway through IGF-1 signaling.
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- In vitro fermentation profiles of undigested fractions from legume and nut
particles are affected by particle cohesion and entrapped macronutrients-
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Abstract:Food Funct., 2022, 13,5075-5088
DOI : 10.1039/D2FO00250G, Paper Widaningrum, Bernadine M. Flanagan, Barbara A. Williams, Francesca Sonni, Pengfei Chen, Deirdre Mikkelsen, Michael J. Gidley
Insoluble undigested food residues are the predominant dietary form of ‘fibre’ from food plants, with the potential for fermentation by microbial species resident within the large intestine.
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- Mechanism of biochanin A alleviating PM2.5-induced oxidative damage based
on an XRCC1 knockout BEAS-2B cell model-
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Abstract:Food Funct., 2022, 13,5102-5114
DOI : 10.1039/D1FO04312A, PaperYue Yu, Ang Li, Shihao Li, Bowen Zheng, Juan Ma, Yazhou Liu, Xiaohong Kou, Zhaohui Xue
PM2.5 induces oxidative/antioxidant system imbalance and produces toxic effects and irreversible damage to the genetic material including chromosomes and DNA. And biochanin A has a moderating effect on these processes.
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- Experimental and numerical evaluation of the effect of micro-aeration on
the thermal properties of chocolate-
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Abstract:Food Funct., 2022, 13,4993-5010
DOI : 10.1039/D1FO04049A, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.D. Bikos, G. Samaras, M. N. Charalambides, P. Cann, M. Masen, C. Hartmann, J. Vieira, A. Sergis, Y. Hardalupas
A multiscale Finite Element Model, validated by heat transfer experiments, is proposed to study the effect of micro-aeration on the thermal properties of chocolate. This model links microstructural changes to changes in chocolate's thermal behaviour.
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- Corn peptides improved obesity-induced non-alcoholic fatty liver disease
through relieving lipid metabolism, insulin resistance and oxidative
stress-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00199C, PaperKang Wei, Yang Wei, Weidong Xu, Feng Lu, Haile Ma
The biological activity was studied of corn peptides (CPs) and a theoretical basis was established for the development of CP-based functional foods and dietary supplements.
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- Folic acid intervention changes liver Foxp3 methylation and ameliorates
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Abstract:Food Funct., 2022, 13,5262-5274
DOI : 10.1039/D1FO04267J, PaperHuichao Zhao, Peiyu Guo, Yuwei Zuo, Yanhui Wang, Hui Zhao, Tongtong Lan, Meilan Xue, Huaqi Zhang, Hui Liang
Folic acid prevented ethanol-induced skewed hepatic Th17/Treg balance and inflammation by inhibiting DNMT3a expression and reducing the methylation rate of Foxp3 DNA, which in turn upregulated the Treg frequency. Figure created with BioRender.com.
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- L-Methionine supplementation attenuates high-fat fructose diet-induced
non-alcoholic steatohepatitis by modulating lipid metabolism, fibrosis,
and inflammation in rats-
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Abstract:Food Funct., 2022, 13,4941-4953
DOI : 10.1039/D1FO03403K, PaperUmashanker Navik, Vaibhav G. Sheth, Nisha Sharma, Kulbhushan Tikoo
Recently, the protective effects of a methionine-rich diet on hepatic oxidative stress and fibrosis have been suggested but not adequately studied.
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- Lactobacillus paracasei PS23 improves cognitive deficits via modulating
the hippocampal gene expression and the gut microbiota in
D-galactose-induced aging mice-
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Abstract:Food Funct., 2022, 13,5240-5251
DOI : 10.1039/D2FO00165A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Li-Hao Cheng, Pin-Yu Chou, An-Tian Hou, Chin-Lin Huang, Wei-Lin Shiu, Sabrina Wang
Probiotic supplements are potential therapeutic agents for age-related cognitive deficits.
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- Anti-hyperlipidemic and ameliorative effects of chickpea starch and
resistant starch in mice with high fat diet induced obesity are associated
with their multi-scale structural characteristics-
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Abstract:Food Funct., 2022, 13,5135-5152
DOI : 10.1039/D1FO04354D, PaperMengliu Zhao, Wenxin Cui, Xinzhong Hu, Zhen Ma
The multi-scale structure and in vivo physiological effects of chickpea starches (UC-S and CC-S) and their corresponding resistant starch (UC-RS and CC-RS) on controlling hyperlipidemia in high fat diet induced obese mice were compared in this study.
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- Enhancement of DPP-IV inhibitory activity and the capacity for enabling
GLP-1 secretion through RADA16-assisted molecular designed rapeseed
peptide nanogels-
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Abstract:Food Funct., 2022, 13,5215-5228
DOI : 10.1039/D1FO04367F, PaperFeiran Xu, Baocai Xu, Hong Chen, Xingrong Ju, Elvira Gonzalez de Mejia
RADA16-assisted molecular designed rapeseed peptide nanogels were used to enhance the DPP-IV inhibitory activity and the capacity for enabling GLP-1 secretion in STC-1 cells.
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- New red-fleshed apple cultivars: a comprehensive review of processing
effects, (poly)phenol bioavailability and biological effects-
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Abstract:Food Funct., 2022, 13,4861-4874
DOI : 10.1039/D2FO00130F, Review ArticleSilvia Yuste, Iziar A. Ludwig, María-Paz Romero, María-José Motilva, Laura Rubió
This review details the first comprehensive overview of new hybrid red-fleshed apples, mainly focusing on their (poly)phenolic composition, the effect of processing, the (poly)phenolic bioavailability and the biological effects.
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- A genome-wide association study revealed the genetic variation and
candidate genes for grain copper content in bread wheat (Triticum aestivum
L.)-
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Abstract:Food Funct., 2022, 13,5177-5188
DOI : 10.1039/D1FO04173H, PaperJianhui Ma, Siyuan Qi, Meng Yuan, Dongyang Zhao, Daijing Zhang, Jinyuan Feng, Jianing Wang, Wei Li, Chengxiang Song, Tianlin Wang, Qingdong Zeng, Jianhui Wu, Dejun Han, Lina Jiang
As an essential microelement, copper plays a crucial role in the human body, and should be improved in wheat grain.
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- Characterization of precipitation from citrus vinegar during ageing:
chemical constituents, formation mechanism and anti-proliferative effect-
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Abstract:Food Funct., 2022, 13,4930-4940
DOI : 10.1039/D2FO00513A, PaperFeifei Hu, Ye Qin, Yiqing Zhou, Lingyue Li, Yingxi Wang, Zhangshuang Deng
Chemical and antiproliferative investigations of the precipitates from fermented citrus vinegar contribute to new insights for polymethoxyflavones enrichment and for reutilizing the precipitates.
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- Screening and bioavailability evaluation of anti-oxidative
selenium-containing peptides from soybeans based on specific structures-
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Abstract:Food Funct., 2022, 13,5252-5261
DOI : 10.1039/D2FO00113F, PaperXing Zhang, Hui He, Jiqian Xiang, Tao Hou
SFQSeM is a potential replacement for inorganic selenium and seleno-amino acids to promote antioxidant capacity and regulate selenium toxicity.
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- The effect of quercetin on diabetic nephropathy (DN): a systematic review
and meta-analysis of animal studies-
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Abstract:Food Funct., 2022, 13,4789-4803
DOI : 10.1039/D1FO03958J, Review ArticleTingyan Hu, Junlun Yue, Qiuwen Tang, Ka-Wing Cheng, Feng Chen, Mijun Peng, Qian Zhou, Mingfu Wang
Quercetin, a flavonoid possessing numerous biological activities, is reported to improve renal injury in diabetic animals.
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- Associating the blood vitamin A, C, D and E status with tuberculosis: a
systematic review and meta-analysis of observational studies-
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Abstract:Food Funct., 2022, 13,4825-4838
DOI : 10.1039/D1FO02827H, Review ArticleFei Xu, Baolan Ma, Dandan Wang, Jialin Lu, Ke Xiong, Jinyu Wang
The current meta-analysis suggested significantly lower blood vitamin A, D and E concentrations in the tuberculosis group than in the control group. The difference in the vitamin C status was inconclusive.
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- Insights from multi-spectroscopic analysis and molecular modeling to
understand the structure–affinity relationship and the interaction
mechanism of flavonoids with gliadin-
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Abstract:Food Funct., 2022, 13,5061-5074
DOI : 10.1039/D1FO03816H, PaperJie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang
An integrated method was applied to investigate the structure–affinity relationship and interaction mechanism between a library of natural flavonoids and gliadin.
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- A high-value-added application of the stems of Rheum palmatum L. as a
healthy food: the nutritional value, chemical composition, and
anti-inflammatory and antioxidant activities-
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Abstract:Food Funct., 2022, 13,4901-4913
DOI : 10.1039/D1FO04214A, PaperXiaofei Shang, Lixia Dai, Jian He, Xiaorong Yang, Yu Wang, Bing Li, Jiyu Zhang, Hu Pan, Ilgekbayeva Gulnaz
SRP is shown to have nutritional value, exhibit anti-inflammatory and antioxidant activities, and have the potential to be utilized as a sustainable resource in the food and pharmaceutical industries.
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- Immunomodulatory effects of mixed Lactobacillus plantarum on
lipopolysaccharide-induced intestinal injury in mice-
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Abstract:Food Funct., 2022, 13,4914-4929
DOI : 10.1039/D1FO04204A, PaperJiahuan Dong, Lijun Ping, Kangyong Zhang, Hongwei Tang, Jie Liu, Deyu Liu, Li Zhao, Smith Etareri Evivie, Bailiang Li, Guicheng Huo
The intestine is the largest digestive and immune organ in the human body, with an intact intestinal mucosal barrier.
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- Bifidobacterium longum relieves constipation by regulating the intestinal
barrier of mice-
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Abstract:Food Funct., 2022, 13,5037-5049
DOI : 10.1039/D1FO04151G, PaperLinlin Wang, Mao Chai, Jialiang Wang, Qiangqing YU, Gang Wang, Hao Zhang, Jianxin Zhao, Wei Chen
Constipation is a major health concern worldwide, requiring effective and safe treatment options.
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- Protective effect of food derived nutrients on cisplatin nephrotoxicity
and its mechanism-
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Abstract:Food Funct., 2022, 13,4839-4860
DOI : 10.1039/D1FO04391A, Review ArticleChaofan Liu, Sajin Zhou, Weibin Bai, Lei Shi, Xiaoling Li
Platinum-based metal complexes, especially cisplatin (cis-diamminedichloroplatinum II, CDDP), possess strong anticancer properties and a broad anticancer spectrum.
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- Bifidobacterium bifidum relieved DSS-induced colitis in mice potentially
by activating the aryl hydrocarbon receptor-
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Abstract:Food Funct., 2022, 13,5115-5123
DOI : 10.1039/D1FO04219J, PaperQing-yu Cui, Xiao-ying Tian, Xi Liang, Zhe Zhang, Rui Wang, Yu Zhou, Hua-xi Yi, Pi-min Gong, Kai Lin, Tong-jie Liu, Lan-wei Zhang
Two Bifidobacterium bifidum strains could exert their anti-inflammatory and intestinal barrier protecting effects both in vitro and in vivo, upregulate the expression of the aryl hydrocarbon receptor (AhR) in mice with DSS-induced colitis.
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- The effect of hydroxy citric acid supplementation with calorie-restricted
diet on metabolic, atherogenic and inflammatory biomarkers in women with
-
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Abstract:Food Funct., 2022, 13,5124-5134
DOI : 10.1039/D1FO03685H, PaperSara Arefhosseini, Helda Tutunchi, Solmaz Nomi-Golzar, Soltanali Mahboob, Zohre Pouretedal, Mehrangiz Ebrahimi-Mameghani
Possible mechanisms of action of hydroxy citric acid (HCA) in the management of NAFLD.
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- Effects of red raspberry polyphenols and metabolites on the biomarkers of
inflammation and insulin resistance in type 2 diabetes: a pilot study-
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Abstract:Food Funct., 2022, 13,5166-5176
DOI : 10.1039/D1FO02090K, PaperReynaldo Moreno Uclés, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán, Marlene Janes, Henrique Cheng, John Finley, Frank Greenway, Jack N Losso
Berry fruits are rich in polyphenolic compounds (PCs) and may promote health benefits.
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- The anti-infective activity of Salvia miltiorrhiza against Staphylococcus
aureus by attenuating accessory gene regulator system-mediated virulence-
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Abstract:Food Funct., 2022, 13,5050-5060
DOI : 10.1039/D1FO01888D, PaperJia-Ming Jiang, Gan Chen, Yu-Yu Chen, Shi-Jie Wan, Si-Min Chen, Han-Gui Ren, Zhi-Xiu Lin, Hui Feng, Hong Zhang, Hong-Xi Xu
Tanshinone IIB isolated from Salvia miltiorrhiza exhibits an antivirulence effect against S. aureus by acting on the agr system.
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- Identification of novel antioxidant peptides from sea squirt (Halocynthia
roretzi) and its neuroprotective effect in 6-OHDA-induced neurotoxicity-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00729K, PaperRui Ma, Qiqi Chen, Yanping Dai, Yan Huang, Qing Hou, Yuting Huang, Kai Zhong, Yina Huang, Hong Gao, Qian Bu
Ocean life contains a wealth of bioactive peptides that could be utilized in nutraceuticals and pharmaceuticals. This study aimed to obtain neuroprotective antioxidant peptides in sea squirt (Halocynthia roretzi) through...
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- Manno-oligosaccharides from cassia seed gum ameliorate inflammation and
improve glucose metabolism in diabetic rats-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03057D, PaperChenxuan Wu, Jun Liu, Yanxiao Li, Nannan Wang, Qiaojuan Yan, Zhengqiang Jiang
Functional oligosaccharides show anti-diabetic effects through inflammation regulation with improved glucose metabolism. In this study, novel prebiotics of manno-oligosaccharides from cassia seed gum (CMOS) were incorporated into diet of streptozocin...
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- Improvement in the metabolic markers of prediabetic subjects due to the
partial substitution of Taiken9 rice by RD43 rice in their daily diet: A
randomized clinical trial-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03664E, PaperPhim on Suklaew, Yi-Chun Han, Charoonsri Chusak, Wen-Chien Lin, Yi-Hsiu Wu, Jyun-Syong Wang, Ya Chu Chang, Yu-Ju Lin, Shu-Ru Zhuang, Hui-Ju Chuang, Sirichai Adisakwattana, Chin-Kun Wang
Although RD43 rice is characterized by high amounts of undigestible starch, its potential health benefits for prediabetic individuals remain unknown. Thus, the effect of regular consumption of RD43 rice on...
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- Bioavailable evaluations on the intestinal absorption and liver
accumulation of torularhodin with rat postprandial mode-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03707B, CommunicationJiayi Li, Qian He, Fuwei Pi, Ben-Xin Wang
Torularhodin, as a new functional carotenoid, possesses great application potentials in disease intervention. However, its absorption process and corresponding mechanism have not been studied. In this study, a rat postprandial...
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- Asiatic acid from Cyclocarya paliurus regulates the autophagy–lysosome
system via directly inhibiting TGF-β type I receptor and ameliorates
diabetic nephropathy fibrosis-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO02445K, PaperXuan-xuan Zhang, Yao Liu, Su-su Xu, Ru Yang, Cui-hua Jiang, Li-ping Zhu, Yin-ying Xu, Ke Pan, Jian Zhang, Zhi-qi Yin
AA could decrease TGF-β1 secretion and suppress tubulointerstitial fibrosis by directly inhibiting TGF-βR1 and activate the autophagy–lysosome system in DN fibrosis.
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- Adherence to a cholesterol-lowering diet and the risk of prostate cancer
-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03795A, PaperMatteo Di Maso, Livia S. A. Augustin, David J. A. Jenkins, Greta Carioli, Federica Turati, Benedetta Grisoni, Anna Crispo, Carlo La Vecchia, Diego Serraino, Jerry Polesel
Adherence to a cholesterol-lowering diet decreases the risk of prostate cancer.
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- Assessment of milk protein digestion kinetics: effects of denaturation by
heat and protein type used-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00542E, PaperEvan Abrahamse, Gabriël G. M. Thomassen, Ingrid B. Renes, Peter A. Wierenga, Kasper A. Hettinga
Both whey protein denaturation and β-casein inclusion increased intact protein loss without affecting absorbable product release during in vitro digestion.
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- HPLC-DAD Analysis, Anti-Inflammatory and Anti-Arthritic potential of
Coronopus didymus (L.) Sm. extracts: Effects on Pro-and Anti-inflammatory
Cytokines, COX-2, I-κβ, NF-κβ and oxidative stress biomarkers-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00207H, PaperAmmara Saleem, Huma Khalid, Muhammad Furqan Akhtar, Alam zeb
Coronopus didymus (L.) Sm. (CD) has been known as traditional herb to treat pain, rheumatism, and inflammation. This study was planned to appraise anti-oxidant, anti-inflammatory and anti-arthritic potential of CD...
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- Myricitrin – a flavonoid isolated from Indian olive tree (Elaeocarpus
floribundus) inhibits Monoamine oxidase in brain and elevates striatal
dopamine levels: therapeutic implications against Parkinson’s disease-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00734G, PaperCHAYAN BANERJEE, Sumangal Nandy, Joy Chakraborty, Deepak Kumar
Flavonoids exhibit several biological activities including Monoamine oxidase (MAO) inhibition, an enzyme that metabolizes several neurotransmitters. Thus, MAO inhibitors are well included in traditional therapeutic practices to fine-tune neuromotor behavior....
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- Dietary soybeans worsen dextran sodium sulfate-induced colitis by
disrupting intestinal ecology-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00446A, PaperKaiyang Chen, Congcong Gao, Ming Tang, Qinchen Dong, Ningyu Wang, Shuli Man, Fuping Lu, HaiKuan Wang
Food mediates susceptibility to inflammatory bowel disease (IBD) associated with the microbiome. Existing studies suggest that a high sugar and high fat diet promotes IBD, but whether a plant-based diet...
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- Pomegranate juice alters the microbiota in breast milk and infant stool: a
pilot study-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00280A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Susanne M. Henning, Jieping Yang, Ru-Po Lee, Jianjun Huang, Gail Thames, Michelle Korn, Dina Ben-Nissan, David Heber, Zhaoping Li
This interventional pilot study demonstrates that ellagic acid and its metabolites are absorbed by the nursing infant from breast milk, excreted in urine and impact the infant's gut microbiome. Phenolic compounds in breast milk might contribute health benefits to infants.
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- Evaluation of the effect of prebiotic sesame candies on loperamide-induced
constipation in mice-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00067A, PaperPengkui Xia, Xia Liu, Tao Hou, Fuchao Zhan, Fang Geng, Ziyang Zhang, Bin Li
Constipation is one of the most common gastrointestinal tract symptoms.
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- Modulation of Lactobacillus rhamnosus GG on the gut microbiota and
metabolism in mice with Clostridioides difficile infection-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00374K, PaperZhengjie Wu, Qiaomai Xu, Silan Gu, Qiangqiang Wang, Yunbo Chen, Longxian Lv, Beiwen Zheng, Kaicen Wang, Shuting Wang, Jiafeng Xia, Lanjuan Li
Clostridioides difficile infection (CDI) is a common nosocomial infection and is an urgent threat to public health.
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- Anti-tumor activity of polysaccharides extracted from Pinus massoniana
pollen against colorectal cancer in vitro and in vivo-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03908C, PaperHongqi Shang, Xiangyun Niu, Wenping Cui, Zhou Sha, Cheng Wang, Teng Huang, Ping Guo, Xiangkun Wang, Panpan Gao, Shuyu Zhang, Kai Wei, Ruiliang Zhu
The prevalence and mortality rate of colorectal cancer (CRC) have been dramatically rising worldwide. Pinus massoniana pollen, a well-known natural nutrition food, is one of the most commonly consumed traditional...
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- Effect of Passiflora setacea juice and its phenolic metabolites on insulin
resistance markers in overweight individuals and on microglia cell
activity-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04334J, PaperIsabella Duarte, Maria Carolina de Souza, Rafaela Curinga, Henrique Matos Mendonça, Livia de Lacerda de Oliveira, Dragan Milenkovic, Neuza Hassimotto, Ana Maria Costa, Juaci Malaquias, Tatiana Karla Borges
Passiflora setacea (PS) is a species of wild Brazilian passion fruit, rich in bioactive compounds. Studies suggested that a diet rich in bioactive compounds can positively modulate inflammation and oxidative...
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- Proanthocyanidins as the main pancreatic lipase inhibitors in chokeberry
fruits-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04429J, PaperDorota Sosnowska, Anna Podsędek, Alicja Z. Kucharska
Pancreatic lipase inhibitors are recognized as important in strategies for the management of overweight and obesity.
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- Blue honeysuckle extracts retarded starch digestion by inhibiting
glycosidases and changing the starch structure-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00459C, PaperXinyue Zhang, Rizwan-ur- Rehman, Songxue Wang, Yanglin Ji, Jing Li, Suwen Liu, Hao Wang
Blue honeysuckle rich in anthocyanins can inhibit starch-digesting enzyme activity. This study evaluated the inhibitory effect and mechanism of blue honeysuckle extract (BHE) on glycosidases (α-amylase and α-glucosidase). BHE was...
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- Effect of sea cucumber peptide on immune response and gut microbiota
composition in the ovalbumin-induced allergic mice-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00536K, Paperliyuan Yun, Wen Li, Tao Wu, Min Zhang
The prevalence of food allergy has increased in Asian countries. The aim of this study was to determine the potential value of sea cucumber peptide (SCP) for anti-allergic therapeutics by...
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- Resazurin-based high-throughput screening method for the discovery of
dietary phytochemicals to target microbial transformation of L-carnitine
into trimethylamine, a gut metabolite associated with cardiovascular
disease-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00103A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Carolina Simó, Tiziana Fornari, Mónica R. García-Risco, Ainize Peña-Cearra, Leticia Abecia, Juan Anguita, Héctor Rodríguez, Virginia García-Cañas
Dietary phytochemicals to target microbial transformation of L-carnitine into trimethylamine.
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- Changes in the intestinal microbiota of healthy adults induced by brown
yogurt and relationships of bacterial taxa with specific components-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03885K, PaperTiemin Jiang, Yi Liang, Bin Liu, Biyuan Liu, Xia Li, Junying Zhao, Jiantao Li, Yanpin Liu, Lijun Chen
Yogurt consumption shows a wide range of effects on the gut microbial composition, and correlation of components in yogurt with the changes of gut microbia remains largely uncharacterized. We aimed...
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- Digestion characteristics of quinoa, barley and mungbean proteins and the
effects of their simulated gastrointestinal digests on CCK secretion in
enteroendocrine STC-1 cells-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00243D, PaperHongdong Song, Qiuyun Fu, Kai Huang, Zhiying Zou, Limin Chen, Hulin Chen, Shaocheng Ge, Jing Wang, Xiao Guan
The demand for plant-based proteins has been rapidly increasing due to sustainability, ethical and health reasons. The present study aimed to investigate the digestion characteristics of three plant proteins (quinoa,...
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- Potential nutritional healthy-aging strategy: Enhanced protein metabolism
by balancing branched-chain amino acids in a finishing pig model-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03970A, PaperLingyu Zhang, Qiuping Guo, Yehui Duan, Wenlong Wang, Yuhuan Yang, Yunju Yin, Saiming Gong, Mengmeng Han, Fengna Li, Yulong Yin
Branched-chain amino acids (BCAAs) have key physiological roles in the regulation of protein synthesis, metabolism, food intake and aging. This study aimed to investigate the protective effect of balanced BCAAs...
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- Ameliorating efficacy of galacto-oligosaccharides on the ovalumin-induced
allergic dermatitis symptoms in Balb/c mice via regulating Th2 immune
response and the ecosystem of gut microbiota-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00157H, PaperKisoo Han, Yejin Ahn, Ki-Bae Hong, H. J. Suh, Kwang-Won Yu, Hoon Kim
In this study, we evaluated the effect of oral administration of galacto-oligosaccharide (GOS) which is famous biological molecules that are comprised of galactose and lactose on ovalbumin (OVA)-induced allergic dermatitis....
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- Polysaccharides from soybean residue fermented by Neurospora crassa
alleviate DSS-induced gut barrier damage and microbiota disturbance in
mice-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00137C, PaperWenli Huang, Zeyuan Deng, Ling Lu, Yaoming Ouyang, Shuyuan Zhong, Ting Luo, Yawei Fan, Liufeng Zheng
Soluble polysaccharides from the microbial fermentation of agricultural by-products were considered as potential functional ingredients mainly having probiotic benefits. Herein, soluble polysaccharides (FSRP) were separated from soybean residue fermented by...
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- Rice bran protein oxidation induced by rancidity alters the gut microbiota
and intestinal permeability in mice-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03308E, PaperFang Li, Zhuoran Kang, Xiaojuan Wu, Wei Wu
Oxidized RBP induced by rice bran rancidity changes the gut microbiota profile, slightly affects the production of SCFAs, and improves the intestinal barrier by upregulating the expression of tight junction proteins.
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- The Effect of In vitro Gastrointestinal Digestion on Phenolic Profiles,
Bioactivities and Bioaccessibility of Rhodiola-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00469K, PaperSheng Zhang, Na Deng, Bisheng Zheng, Tong Li, Ruihai Liu
Rhodiola contains a wide variety of phytochemicals, which might be correlated with its severe growth environment. In this study, changes in the phenolic profiles, antioxidant and antiproliferative activities of Rhodiola...
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- HPLC-DVD combined with chemometrics to analyze the correlation between the
Q-marker content and color of Corni Fructus-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03866D, PaperTing Wang, Yilin Bai, Yating Du, Shujing An, Binkai Han, Xiaolin Yang, Changfen He, Haoqiang Sun, Ke Zhao, Xiaochang Xue, Jiefang Kang
A standard colorimetric card related to Corni Fructus (CF) quality was established, which simplified the quality evaluation process and improved the accuracy of the visual evaluation of CF.
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- Arbutus unedo leaf extracts as potential dairy preservatives: case study
on quark cheese-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04158D, PaperNabila Derbassi, Mariana C. Pedrosa, Sandrina Heleno, Filipa Fernandes, Maria Inês Dias, Ricardo C. Calhelha, Paula Rodrigues, Marcio Carocho, Isabel C. F. R. Ferreira, Lillian Barros
The plant kingdom is an endless source of molecules that can be applied in almost all realms of society.
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- Oligosaccharides derived from Lycium barbarum ameliorate glycolipid
metabolism and modulate the gut microbiota community and the faecal
metabolites in a type 2 diabetes mouse model: metabolomic bioinformatic
analysis-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO02667D, PaperHao Liu, Zheng Zhang, Jianpeng Li, Wei Liu, Mohamad Warda, Bo Cui, A. M. Abd El-Aty
This study investigated how Lycium barbarum oligosaccharides improve glycolipid metabolism and modulate the gut microbial community and faecal metabolites in a mouse model of type 2 diabetes.
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- Metabolic regulation of (-)-epicatechin and the colonic metabolite
2,3-dihydroxybenzoic acid on the glucose uptake, lipid accumulation and
insulin signalling in cardiac H9c2 cells-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00182A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Esther Gracia-Diez, M. Elvira López-Oliva, Jara Pérez-Jiménez, Maria Angeles Martin, Sonia Ramos
Epicatechin (EC) and main colonic phenolic acids derived from flavonoid intake have been suggested to exert healthful effects, although their mechanism of action remains unknown. Heart damage is highly prevalent...
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- Bioaccessibility of essential lipophilic nutrients in a chloroplast-rich
fraction (CRF) from agricultural green waste during simulated human
gastrointestinal tract digestion-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00604A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jutarat Wattanakul, Mansor Syamila, Randa Darwish, Mohamed A. Gedi, Poramat Sutcharit, Chao Chi, Patchaniya Akepach, Moulay Sahaka, Brigitte Gontero, Frédéric Carrière, David A. Gray
The lipophilic nutrients in a chloroplast-rich fraction derived from pea vine postharvest field-residue are released in an in vitro digestion model; the extent of their release (bioaccessibility) is affected by heat-treatment of biomass or juice.
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- Rapid proteolysis of gluten-derived immunogenic peptides in bread by
actinidin in a combined in vivo and in vitro oro-gastrointestinal
digestion model-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03740D, PaperIsuri Jayawardana, Mike Boland, Trevor S Loo, Warren McNabb, Carlos Montoya
This study aimed to determine the ability of actinidin, a cysteine protease in green kiwifruit (Actinidia deliciosa), to hydrolyse wheat proteins and gluten-derived immunogenic peptides from a commonly consumed food...
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- DEVELOPMENT OF HEALTHY MILK AND YOGURT PRODUCTS FOR REDUCING METABOLIC
DISEASES USING CYCLODEXTRIN AND OMEGA-3 FATTY ACIDS FROM FISH OIL.-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00578F, PaperBerenice Guadarrama-Flores, Adrián Matencio, Silvia Navarro-Orcajada, Ismael Martinez-Lede, Irene Conesa, Francisco José Vidal-Sanchez, Francisco Garcia-Carmona, José Manuel López Nicolás
The food industry is constantly attempting to develop better products that will have a positive effect on health. Feiraco® and Clesa®, expressed their intention to create novel products using UNICLA®...
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- Tea polyphenols alleviate the adverse effects of diabetes on oocyte
quality-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03770F, PaperJun Lu, Shu-Xian Zhao, Man-Yu Zhang, Peng-Yuan Ji, Shuo Chao, Li-Jun Li, Shen Yin, Lei Zhao, Hua Zhao, Qing-Yuan Sun, Zhao-Jia Ge
Maternal diabetes reduces oocyte quality. The decreased oocyte quality can be alleviated by tea polyphenols in vitro, such as mitochondrial function, meiosis, and DNA damage.
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- Bacillus amyloliquefaciens SC06 alleviates the obesity of ob/ob mice and
improves their intestinal microbiota and bile acid metabolism-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03170H, PaperZhonghua Zeng, Yuanhao Zhou, Yibin Xu, Song Wang, Baikui Wang, Zihan Zeng, Qi Wang, Xiaolin Ye, Lu Jin, Min Yue, Li Tang, Peng Zou, Pengwei Zhao, Weifen Li
Bacillus amyloliquefaciens SC06 can ameliorate obesity in male ob/ob mice by reshaping the intestinal microbial composition, changing metabolites, with deep correlation between phenotypes, and regulating bile acid metabolism via the FXR signaling pathway.
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- Camellia (Camellia oleifera bel.) seed oil reprograms gut microbiota and
alleviates lipid accumulation in high fat-fed mice through the mTOR
pathway-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04075H, PaperJing Gao, Li Ma, Jie Yin, Gang Liu, Jie Ma, SiTing Xia, SaiMing Gong, Qi Han, TieJun Li, YongZhong Chen, YuLong Yin
CO improves dyslipidemia and alleviates lipid accumulation in HF-fed mice, the molecular mechanisms possibly associated with the reorganization of gut microbiota, in particular, Alistipes and Dubosiella, mediated the inhibition of the mTOR pathway.
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- Metabolic perturbations and health impacts from exposure to combination of
mutiple harmful Maillard reaction products on Sprague-Dawley rats-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00143H, PaperWei Quan, Yong Lin, Chaoyi Xue, Yong Cheng, Jie Luo, Aihua LOU, Maomao Zeng, Zhiyong He, Qingwu W. Shen, J. Chen
The present study aimed to investigate the metabolic perturbations and health impacts of the co-accumulation of Maillard reaction products (MRPs), including acrylamide, harmane, and Nε-(carboxymethyl)lysine (CML), via serum biochemical and...
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- Lupeol inhibits the proliferation and migration of MDA-MB-231 breast
cancer cells via a novel crosstalk mechanism between autophagy and the EMT
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00483F, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xin Zhang, Zhanwang Gao, Kehan Chen, Qingyuan Zhuo, Meixian Chen, Jiansong Wang, Xiaoping Lai, Lingli Wang
Lupeol could inhibit TNBC cells by inducing autophagy, and additionally suppressing the tumor migration and invasion.
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- Control of starch–lipid interactions on starch digestibility during
hot-extrusion 3D printing for starchy foods-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D2FO00558A, PaperZipeng Liu, Ling Chen, Bo Zheng
In the HE-3DP environment, thermal shear force promotes hydrophobic interactions between starch and lipids, forming a V-type starch–lipid complex with a compact and ordered structure, thus enhancing the anti-digestibility of starch.
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- Beneficial effects of blueberry supplementation on the components of
metabolic syndrome: a systematic review and meta-analysis-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO03715C, Review ArticleHushyar Azari, Ashti Morovati, Bahram Pourghassem Gargari, Parvin Sarbakhsh
Metabolic syndrome (MetS) is a combination of interconnected disorders that puts a heavy burden on society.
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- Lactobacillus plantarum 23-1 improves intestinal inflammation and barrier
function through TLR4/NF-κB signaling pathway in obese mice-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04316A, PaperZhijing Liu, Jiale Zhao, Rongbo Sun, Min Wang, Kunynag Wang, Yanan Li, Hang Shang, Juncai Hou, Zhanmei Jiang
As a natural active ingredient, lactic acid bacteria have potential anti-inflammatory effects. In this study, male C57BL/6J mice were given high-fat diet (HFD) to establish an obese mouse model. Lactobacillus...
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- YEAST CARBOXYMETHYL-GLUCAN IMPROVES ENDOTHELIAL FUNCTION AND INHIBITS
PLATELET AGGREGATION IN SPONTANEOUSLY HYPERTENSIVE RATS-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03492H, PaperLorena Soares Bezerra, Marciane Magnani, Tatiana Pimentel, Julio Cesar Pinheiro Lucio de Oliveira, Francisca Manuela de Souza Freire, Arthur José Pontes Oliveira de Almeida, Mathania Silva de Almeida Rezende, Islânia Giselia Albuquerque Gonçalves, Isac Almeida de Medeiros , Robson Cavalcante Veras
Carboxymethyl-glucan is a semi-synthetic derivative of β-D-glucan, a polysaccharide widely found in several natural sources, such as yeast, fungi, and cereals. This compound has beneficial effects on health and is...
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- Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice:
mechanistic insights-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04004A, PaperPengkui Xia, Tao Hou, Muyuan Ma, Sha Li, Hong Jin, Xuan Luo, Jing Li, Fang Geng, Bin Li
This study is aimed to explore the protective effect of konjac oligosaccharides (KOS) on inflammatory bowel disease in colitis mice. During the experimental period, colitis mice were administered with 200mg/kg...
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- The galloyl moiety enhances inhibitory activity of polyphenols against
adipogenic differentiation in 3T3-L1 preadipocytes-
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Abstract:Food Funct., 2022, Advance Article
DOI : 10.1039/D1FO04179G, PaperJinming Peng, Wenjun Wen, Ruifeng Wang, Kaikai Li, Gengsheng Xiao, Chunmei Li
The galloyl moiety in the structure of polyphenols has a great contribution to their inhibition of adipogenic differentiation.
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- Resin glycosides in aerial parts of Ipomoea batatas are potent lipase
inhibitors: potential upcycling of sweet potato by-products to combat
obesity-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00555G, PaperJoanne Yi Hui Toy, Zhixuan Song, Dejian Huang
Sweet potato (Ipomoea batatas) is a staple food crop that is cultivated globally. While the tubers are widely utilised in the food industry, 95 – 98% of sweet potato leaves...
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- Potential health effects of brewers’ spent grain as a functional food
ingredient assessed by markers of oxidative stress and inflammation
following gastro-intestinal digestion and in a cell model of the small
intestine-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO03090F, PaperDiane Merten, Lara Erman, Gianlucca Marabelli, Bernadette Leners, Yannick Ney, Jawad Nasim, Claus Jacob, Job Tchoumtchoua, Sébastien Caiot, Torsten Bohn
Brewer`s spent grains (BSG) are a by-product of the beer-brewing industry, often employed as animal feedingstuffs. With BSG being rich not only in proteins, lipids, dietary fiber but also in...
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- Chondroitin sulfate deposited on the foxtail millet prolamin/caseinate
nanoparticles to improve physicochemical properties and enhance cancer
therapeutic effect-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00572G, PaperXiao Chen, Yan-Chao Wu, Pi-xian Gong, Yu-He Zhang, Hui-Jing Li
In this study, Curcumin (Cur) loaded chondroitin sulfate (CS)−sodium caseinate (NaCas) stabilized foxtail millet prolamin (FP) composite nanoparticles (NPs) was fabricated in one-pot process. FP was capable of self-assembly through...
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- Preparation, structure characterization and prebiotic potential of
mulberry leaf oligosaccharide-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D1FO04048K, PaperTeng-Gen Hu, Hong Wu, Yuanshan Yu, Xu Yujuan, Er-Na Li, S. Liao, Peng Wen, Yu-Xiao Zou
The present study purified a main oligosaccharide fraction (MLO 1-2) from enzymatic hydrolysate of mulberry leaf polysaccharide by DEAE-52 cellulose and gel column chromatography. The physicochemical properties of MLO 1-2...
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- Bioaccessibility and movement of phenolic compounds from tomato (Solanum
lycopersicum) during in vitro gastrointestinal digestion and colonic
fermentation.-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00223J, PaperChuqi Wang, Hanjing Wu, ziyao liu, Colin Barrow, Frank Dunshea, Hafiz Suleria
Tomatoes (Solanum lycopersicum) are of great significance in terms of the worldwide consuming nutritional diets. Large amounts of nutritional compounds such as phenolics, flavonoids, carotenoids, vitamins, and minerals have drawn...
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- 6'-O-caffeoylarbutin from Que Zui tea ameliorates acetaminophen-induced
liver injury via enhancing antioxidant ability and regulating PI3K
signaling pathway-
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Abstract: Food Funct., 2022, Accepted Manuscript
DOI : 10.1039/D2FO00507G, PaperYongpeng Wang, Yudan Wang, Ya-Ping Liu, Jianxi Cao, Meilian Yang, Yifen Wang, Afsar Khan, Tianrui Zhao, Guiguang Cheng
Que Zui tea (QT), a traditional herbal tea in China, has significant hepatoprotective effect. 6'-O-caffeoylarbutin (CA) is the most abundant chemical compound in the QT. However, the hepatoprotective effect of...
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