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Food & Function
Journal Prestige (SJR): 1.209  Citation Impact (citeScore): 4 Number of Followers: 6  Hybrid journal (It can contain Open Access articles)ISSN (Print) 2042-6496 - ISSN (Online) 2042-650X Published by RSC  [50 journals]
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- Isoquercitrin Alleviates Lipopolysaccharide-Induced Intestinal Mucosal
Barrier Damage in Mice by Regulating TLR4/MyD88/NF-κB Signaling Pathway
and Intestinal Flora-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03319H, PaperEnhui Tang, Tong Hu, Zhaokang Jiang, Xiaojun Shen, Huan Lin, Haiyan Xian, Xinlan Wu
Intestinal mucosal barrier damage is closely associated with the development of several intestinal inflammatory diseases. Isoquercitrin (IQ) is a natural flavonoid compound derived from plants, which exhibits high antioxidant and...
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- Presence of digestible starch impacts in vitro fermentation of resistant
starch-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO01763J, Paper
Open Access 
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Cynthia E. Klostermann, Martha F. Endika, Dimitrios Kouzounis, Piet L. Buwalda, Paul de Vos, Erwin G. Zoetendal, Johannes H. Bitter, Henk A. Schols
Awareness is required for the presence of digestible starch when studying in vitro fermentation of resistant starch (RS). Such starch may steer and overrule the fermentation of RS, thereby affecting the evaluation of the prebiotic potential of RS.
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- Age differences in the impact of dietary salt on metabolism, blood
pressure and cognitive function in male rats-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04211A, Paper Open Access 
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.FEN SUN, Jin-Yang Zhang, Lu-Ping Zhao, Qi Jin, Chao Jin, Qiu-Xiang Wang, Jun-Tao Xu, Meng-Jia Yin
The influence of salt consumption on physiological processes, especially blood pressure (BP), metabolism, and cognition, remains a topical concern. While guidelines endorse reduced salt diets, there are gaps in understanding...
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- Immunoregulation of bovine lactoferrin together with osteopontin promotes
immune system development and maturation-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03515H, PaperChuangang Li, Yao Lu, Jian Wang, Biao Liu, Ignatius Man-Yau Szeto, Wen Zhang, Ran Bi, Sufang Duan, Rui Quan, Xuemin Wang, Yixuan Li, Wei Xiong, Jiazeng Sun, Yanan Sun
The immune system of infants is partly weak and immature, and supplementation of infant formula can be of vital importance to boost development of the immune system. Lactoferrin (LF) and...
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- Effects of (-)-epicatechin on hepatic triglyceride metabolism
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03666A, PaperZahra Mostofinejad, E. Cremonini, Jiye Kang, Patricia Oteiza
(-)-Epicatechin (EC) consumption is associated to an improvement of hyperlipemia and other metabolic changes linked to obesity and western-style diets. This work investigated the effects of EC on triglyceride (TG)...
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- Synbiotic formulation of Lactobacillus reuteri and inulin alleviates
ASD-like behaviors in a mouse model: the mediating role of the gut-brain
axis-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02663A, PaperChuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu
Autism Spectrum Disorder (ASD), a complex neurodevelopmental disorder marked by social communication deficits and repetitive behaviors, may see symptom amelioration through gut microbiota modulation. This study investigates the effects of...
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- Exploration of grape pomace peels and amaranth flours as functional
ingredients in the elaboration of breads: phenolic composition,
bioaccessibility, and antioxidant activity-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04494G, PaperValeria Tironi, Mariela Rodríguez, Federico Bianchi, Barbara Simonato, Corrado RIZZI, Ariel R. Fontana
This study evaluated the incorporation of two ingredients as a source of bioactive compounds: amaranth flour (AF) and grape pomace peels flour (GP) to improve the nutritional qualities and functional...
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- Pterostilbene alleviates abdominal aortic aneurysm via inhibiting
macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO01235B, PaperHuoying Cai, Lin Huang, Mingshan Wang, Ruiming Liu, Jiacong Qiu, Yuansen Qin, Xi Yao, Shenming Wang, Chen Yao, Zuojun Hu, Yu Zhou
Our findings provide evidence that macrophage pyroptosis contributes to the development of AAA and that the activation of the miR-146a/TRAF6 axis by pterostilbene protects against macrophage pyroptosis and AAA formation.
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- D-mannose promotes recovery from experimental colitis by inducing AMPK
phosphorylation to stimulate epithelial repair-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03146B, PaperHaojie Zhang, Xue Zhao, Yifei Gao, Yao Shi, Lina Wei, Jingxin Li, Chuanyong Liu, Xuelian Ma
Delayed mucosal healing and impaired intestinal epithelial barrier function have been implicated in the pathogenesis of ulcerative colitis (UC). Accordingly, restoration of epithelial barrier function as a means to reshape...
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- Effects of unfolding treatment assisted glycation on the IgE/IgG binding
capacity and antioxidant activity of ovomucoid-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO04035F, PaperXian Xia, Jiangdong Li, Rui Liang, Yi Li, Xiaojuan Ma, Ying Yang, Daniel Lozano-Ojalvo
The IgE binding ability of ovomucoid was sharply reduced by unfolding assisted glycation.
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- Maternal inulin alleviates high-fat diet-induced lipid disorder in
offspring by epigenetically modulating hypothalamus feeding
circuit-related genes-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02223D, PaperQian Zhang, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Tong Wang
Maternal inulin intervention activates hypothalamic Socs3, Npy, and Il6 gene methylation, inhibits Lepr gene methylation, and moderates the hypothalamus feeding circuit, leading to a decrease in food intake and body weight in male offspring.
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- Targeted development of collagen active peptides based on composite enzyme
hydrolysis: study on structure-activity relationship-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04455F, PaperXinnuo Hu, Yanjun Yang, Cuihua Chang, Junhua Li, Yujie Su, Luping Gu
In this study, alkaline, papain, and ginger protease were used to enzymatically hydrolyze fish skin collagen. The peptide molecular distribution and sequence were measured using HPLC and ICP-MS-MS, with papain/alkaline...
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- Exploiting Locusta migratoria as a source of bioactive peptides with
anti-fibrosis properties using an in silico approach-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04246D, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Carla Sílvia Silva Teixeira, Rita Biltes, Caterina Villa, Sergio Sousa, Joana Costa, Isabel M. P. L. V. Ferreira, Isabel Mafra
Edible insects have been proposed as an environmentally and economically sustainable source of protein, being considered as an alternative food, especially to meat . The migratory locust, Locusta migratoria, is...
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- Hesperidin promotes fatty acid β-oxidation by activating SIRT1/PGC1α to
improve NAFLD induced by high-fat-diet-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04348G, PaperTong Nie, Xin Wang, Aqun Li, Anshan Shan, Jun Ma
Reducing fat deposits in hepatocytes is a direct treatment for nonalcoholic fatty liver disease (NAFLD) and fatty acid metabolic processes mediated by fatty acid β-oxidation are important for the prevention...
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- Ganoderma lucidum methyl ganoderate E extends lifespan and modulates
aging-linked indicators in Caenorhabditis elegans-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04166B, PaperNkwachukwu Oziamara Okoro, Arome Solomon Odiba, Junjie Han, Patience Ogoamaka Osadebe, Edwin Ogechukwu Omeje, Liao Guiyan, Yichen Liu , Cheng Jin, Wenxia Fang, Hongwei Liu, Bin Wang
Methyl Ganoderate E (MGE) is a triterpenoid derived from Ganoderma lucidum (Reishi), an edible mushroom, commonly processed into food forms such as soups, drinks, culinary dishes, and supplements. MGE has...
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- The arsenic-lowering effect of Inulin type prebiotics in end stage renal
disease: a randomized crossover trial-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO01843A, PaperChenjiang Ying, Li Li, Jing Zhao, Jinxue Wang, Qianqian Xiong, Xuechun Lin, Xiaolei Guo, Fan Peng, Wangqun Liang, Xuezhi Zuo
Background: Circulatory imbalance of trace elements is frequent in end stage renal disease (ESRD), leading to essential element deficiency and toxic element excess. The present study aimed to investigate whether...
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- Bifidobacterium animalis subsp. lactis Boosts Neonatal Immunity:
Unravelling Systemic Defences against Salmonella-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03686C, PaperChunxiu Lin, Yugui Lin, Shunhe Wang, Jialiang Wang, Xuhua Mao, Yonghua Zhou, Hao Zhang, Wei Chen, Gang Wang
Bifidobacterium animalis subsp. lactis may be a useful probiotic intervention for regulating neonatal intestinal immune responses and counteracting Salmonella infection. However, recent research has focused on intestinal immunity, leaving uncertainties...
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- Ligilactobacillus acidipiscis YJ5 modulates the gut microbiota and
produces beneficial metabolites to relieve constipation by enhancing
mucosal barrier-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03259K, PaperFengqin Feng, Fei Shen, Qianqian Wang, Sami Ullah, Ya Pan, Minjie Zhao, Chen Ming, Jing Wang, Hao Zhong
Constipation is a prevalent gastrointestinal (GI) problem affecting a large number of individuals. This study aimed to investigate peristalsis-promoting potential characteristics of Ligilactobacillus acidipiscis YJ5 and the underlying molecular mechanism....
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- Non-starch polysaccharides from kidney beans: Comprehensive insights in
extraction, structure, physicochemical, and nutritional properties-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03801G, Review ArticleChunli Kong, Caiping Duan, Yixuan Zhang, Yiying Wang, Zheng Yan, Sumei Zhou
Kidney beans (Phaseolus vulgaris L.) are an important legume source of carbohydrates, proteins, and bioactive molecules, and have attracted increasing attention for their high nutritional value and sustainability. Non-starch polysaccharides...
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- Insoluble/soluble fraction ratio determines effects of dietary fiber on
gut microbiota and serum metabolites in healthy mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04068B, PaperYanli Zhang, Jielun Hu, Yadong Zhong, Shuai Liu, Liandi Liu, Xinyi Mu, Chunhua Chen, Shenji Yang, Guohao Li, Duoduo Zhang, Xinru Huang, Jingrui Yang, Xiaojun Huang, Shuigen Bian, S. P. Nie
Both soluble dietary fiber (SDF) and insoluble dietary fiber (IDF) act as a pivotal role in keeping gut microbiota homeostasis, whereas whether the effects of different ratios of IDF and...
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- Anti-diabetic effects of natural and modified ‘Ganzhou’ navel orange
peel pectin on type 2 diabetic mice via gut microbiota-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO04118B, PaperChao Du, Feng Zuo, Yang Cao, Yanqing Zang
GOP and MGOP ameliorate glucose and lipid metabolism and increase the content of SCFAs in T2DM. In addition, MGOP regulates the composition of gut microbiota, thereby maintaining the balance of gut microbiota by changing the phenotype of bacterial.
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- Diallyl trisulfide inhibits
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via
modulating gut microbiota and the PPARγ/NF-κB pathway-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03914E, PaperZhuo Qu, Jiahui Tian, Jiachen Sun, Ying Shi, Jianqiang Yu, Wannian Zhang, Chunlin Zhuang
Smoking is the primary risk factor for developing lung cancer. Chemoprevention could be a promising strategy to reduce the incidence and mortality rates of lung cancer. Recently, we reported that...
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- (R,S)-Equol 7-β-D-glucuronide, but not other circulating isoflavone
metabolites, modulates migration and tubulogenesis in human aortic
endothelial cells targeting the VEGF pathway-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03946C, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Juan Antonio Gimenez Bastida, María Á. Ávila-Gálvez, Alicia Martínez-López, Diana García-Moreno, Juan Carlos Espin, Antonio Gonzalez-Sarrias
Current knowledge indicates that the consumption of isoflavone-rich foodstuffs can have a beneficial impact on cardiovascular health. Less clear is to what extent these isoflavones act as the main actors...
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- Estrogen receptors-mediated health benefits of phytochemicals: A review
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04702D, Review ArticleJunfeng Li, Jia Yu, Haoyang Zou, Jie Zhang, Li Ren
Estrogen receptors (ERs) are transcription factors with two subtypes: estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ), which are essential for the maintenance of human health and play a...
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- Chemopreventive effects of α-tocopherol and its long-chain metabolites
α-13’-hydroxy- and α-13’-carboxychromanol in LT97 colon adenoma
cells-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02826G, PaperWiebke Schlörmann, Sijia Liao, Tülin Dinc, Stefan Lorkowski, Maria Wallert, Michael Glei
Anti-cancer effects of vitamin E (tocopherols) have been studied extensively. While in vitro and animal studies showed promising results regarding anti-cancer effects of tocopherols, human intervention studies failed to reproduce...
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- Total and different dietary fiber subtypes and the risk of all-cause,
cardiovascular, and cancer mortality: a dose–response meta-analysis of
prospective cohort studies-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D2FO04024G, Review ArticleAmin Mirrafiei, Ahmad Jayedi, Sakineh Shab-Bidar
We aimed to conduct a comprehensive review of the association between dietary fiber and the risk of mortality.
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- Effects of Fu brick tea polysaccharides on gut microbiota and fecal
metabolites of HFD/STZ-induced type 2 diabetes rats-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO04215D, PaperXiangnan Zhang, Qiannan Li, Ning Han, Chaofan Song, Yangnan Lin, Liansheng Zhang, Daoyuan Ren, Yan Zhao, Xingbin Yang, Ting Li
The antidiabetic effects and underlying mechanisms of the polysaccharides extracted from Fu brick tea (FBTP) were investigated in high-fat diet/streptozotocin-induced type 2 diabetes mellitus (T2DM) rats.
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- Association between dietary pattern and chronic kidney disease combined
with hyperuricemia-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03354F, PaperMengrui Luo, Tiancong Liu, Hao Ju, Yang Xia, Chao Ji, Yu-Hong Zhao
Background. Chronic kidney disease (CKD) combined with hyperuricemia is a concerning health issue, but the association between this condition and dietary patterns remains poorly understood. Methods. The cross-sectional study was...
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- The protective effects of beta-mangostin against sodium iodate-induced
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03568A, PaperYuan-Yen Chang, Meilin Wang, Jui-Hsuan Yeh, Shang-Chun Tsou, Tzu-Chun Chen, Min-Yen Hsu, Yi-Ju Lee, Inga Wang, Hui-Wen Lin
Previous studies have indicated that NaIO3 induces intracellular reactive oxygen species (ROS) production and has been used as a model for age-related macular degeneration (AMD) due to the selective retinal pigment epithelium (RPE) cell damage it induces.
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- Ingredients, structure and reconstitution properties of instant powder
foods and the potential for healthy product development: A comprehensive
review-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04216B, Review ArticleYi Ren, Fuhuai Jia, Duo Li
Instant foods are widely presented in powder forms across different food segments, which potentially can be formulated with functional or beneficial compounds to provide health benefits. Many reconstituted instant powder...
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- Exploring immunoregulatory properties of a phenolic-enriched maple syrup
extract through integrated proteomics and in vitro assays-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04026G, PaperTess Puopolo, Ying Chen, Hang Ma, Chang Liu, Navindra P Seeram
Our laboratory has established a comprehensive program to investigate the phytochemical composition and nutritional/medicinal properties of phenolic-enriched maple syrup extract (MSX). Previous studies support MSX’s therapeutic potential in diverse disease...
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- In vitro digestion of high-lipid emulsions: towards a critical
interpretation of lipolysis-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03816E, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Paula K. Okuro, Michèle Viau, Sébastien Marze, Sophie Laurent, Rosiane L. Cunha, Claire Berton-Carabin, Anne Meynier
A holistic interpretation including FFA titration and evaluation of lipolytic products appears of great relevance to capture the complexity of in vitro lipid digestion.
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- Inhibitors of human bitter taste receptors from the five-flavour berry,
Schisandra chinensis-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02303F, CommunicationRyan Soh, Lin Fu, Wei Mei Guo, Wei-Guang Seetoh, Ann Koay
Dibenzocyclooctadiene lignans inhibit several bitter taste receptors and may be useful compounds in bitterness reduction of functional foods.
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- Targeting DSS-Induced Ulcerative Colitis: Evaluating the Therapeutic
Potential of WPI-Stachyose Conjugates-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03598K, PaperZi-han Wang, Guang-yao Zhang, Cong Sun, Shu-Xin Ning, Da-Yong Zhou, Liang Song
The pursuit for food-based alternatives to conventional therapies for ulcerative colitis (UC) demands immediate attention. In prior investigations, we synthesized WPI-stachyose conjugates through the Maillard reaction, identifying them as functional...
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- In vitro-simulated intestinal flora fermentation of Porphyra haitanensis
polysaccharides obtained by different assisted extractions and their
fermented products against HT-29 human colon cancer cells-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO04421A, PaperShiqi Shen, Tao Hong, Zhiyu Liu, Shuji Liu, Hui Ni, Zedong Jiang, Yuanfan Yang, Mingjing Zheng
Herein, the in vitro-simulated intestinal flora fermentation of Porphyra haitanensis polysaccharides with microwave, ultrasonic, ultra-high pressure-assisted extraction and their fermented products against HT-29 human colon cancer cells were studied.
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- The dietary inflammatory index and new-onset hypertension in Chinese
adults: a nationwide cohort study-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03767C, PaperZe Xu, Xue Li, Li Ding, Zhaofeng Zhang, Yongye Sun
A lower inflammatory potential diet can reduce the risk of developing hypertension in Chinese adults.
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- Tibetan tea consumption prevents obesity by modulating cellular
composition and metabolic reprogramming of white adipose tissue-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03506A, PaperSongqi Duan, Hongyu Li, Ziqi Wang, Junqi Li, Weimin Huang, Zhengfeng Fang, Cheng Li, Zhen Zeng, Baofa Sun, Yuntao Liu
Obesity, a global health concern, is linked with numerous metabolic and inflammatory disorders. Tibetan tea, a traditional Chinese beverage rich in theabrownin, is investigated in this study for its potential...
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- Preparation of a novel expandable konjac fiber under different freezing
temperatures and exploration of its digestion regulation functions-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03814A, PaperSha Li, Longchen Shang, Yuan Yuan Chen, Rong Song, Jing Li, Bin Li
A new form of konjac fiber was successfully prepared, and it could instantaneously expand in contact with digestive fluid. The expanded konjac fiber could inhibit the digestion of the ingested...
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- Evidence Construction of Garlic Supplements against Diabetic Kidney
Disease: A Preclinical Meta-analysis and Systematic Review-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02407E, Review ArticleYayi Jiang, Zihan Li, Rensong Yue, Guojie Liu, Maoyi Yang, Caiyi Long, Dawei Yan
Garlic (Allium sativum L.) is a popular spice that is widely used for food and medicinal purposes and has shown potential effects on diabetic kidney disease (DKD). Nevertheless, systematic preclinical...
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- Ethylcoprostanol reduces the proliferation of human colorectal cancer
cells and alleviates cholesterol metabolites-induced cytotoxicity in
non-tumor colon cells: Molecular and biological mechanism-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO01868G, PaperMussa Makran, Guadalupe Garcia-Llatas, Amparo Alegria, Antonio Cilla
Sterols can be metabolized by gut microbiota. The cholesterol metabolites have been proposed as promoters of colorectal cancer (CRC), while the effect of plant sterol metabolites is unknown. The aim...
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- The digestion and absorption characteristics of human milk phospholipid
analogs: a combination study between in vitro and in vivo-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02779A, PaperJiaxin Shen, Yanping Wu, Teng Wei, Yangzheng He, Xiaoru Liu, Zeyuan Deng, Jing Li
The digestion and absorption characteristics of human milk phospholipids analog.
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- Investigation of the allergenicity alterations of shrimp tropomyosin as
glycated by glucose and maltotriose containing advanced glycation end
products-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04440H, PaperBin Yang, Ziye Zhang, Lichun Liu, Zhenxing Li, Hong Lin
Tropomyosin (TM) is the major allergen in shrimp that known to be the primary trigger for shrimp induced food allergy. Our previous reports suggest that glycation could reduce the allergenicity...
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- Astaxanthin alleviates fine particulate matter (PM2.5)-induced lung injury
in rats by suppressing ferroptosis and apoptosis-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03641C, PaperBowen Yin, Jingyi Ren, QIqi Cui, Xuanyi Liu, Ziyi Wang, Huanting Pei, Jinshi Zuo, Yadong Zhang, Rui Wen, Xiaoya Sun, Weican Zhang, Yuxia Ma
Objectives: Fine particulate matter (PM2.5), a small molecule particulate pollutant, can be dispatched to the lungs via respiration and cause lung damage. Currently, effective strategies and measures are lacking...
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- Fermented cereal-origin gerobiotic cocktails promote healthy longevity in
Caenorhabditis elegans-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02984K, PaperThiruppathi Govindhan, Mohankumar Amirthalingam, Kalaiselvi Duraisamy, Jeong Hoon Cho, Shinkichi Tawata, Sundararaj Palanisamy
Gerobiotic synergism reveals the secrets to healthy longevity in Caenorhabditis elegans.
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- A review of ginger polysaccharides: the extraction, purification,
structure–bioactivity correlations, and applications-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03552B, Review Articleyuan wu, Binghang Li, miaomiao chen, Bing Liu, Liangliang Jiang
Ginger has long been recognized as a widespread source of herbal medicine and traditional spices. Among its various bioactive components, ginger polysaccharides (GPs) have drawn the attention of scholars globally...
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- Whole grain germinated brown rice alleviates hyperlipidemia by modulating
gut microbiota and metabolisms of cholesterol and lipid in the high-fat
diet-induced mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03288D, PaperShuai Han, Xiuxiu Wu, Lingfen Zhu, Han Lu, Xuke Ling, Yi Luo, Zuomin Hu, Yaping Zhou, Yiping Tang, Feijun Luo
Hyperlipidemia is a common clinical disorder of lipid metabolism disease in modern society and is considered to be one of the major risk factors leading to cardiovascular related diseases. Germinated...
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- Ergothioneine suppresses hepatic stellate cell activation via promoting
Foxa3-dependent potentiation of the Hint1/Smad7 cascade and improves
CCl4-induced liver fibrosis in mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03643J, PaperGuangwen Shu, Xiao Lei, Guangqiong Li, Tiantian Zhang, Chuo Wang, Anning Song, Huifan Yu, Xiaoming Wang, Xukun Deng
EGT is a bioactive compound derived from certain edible mushrooms. Here, we showed that EGT inhibits HSC activation and improves CCl4-induced mouse liver fibrosis by promoting nuclear translocation of Foxa3 in HSCs to potentiate the Hint1/Smad7 axis.
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- Preparation, Identification, Activity Prediction, Protective Effects on
IR-HepG2 Cells of Five Novel DPP-IV Inhibitory Peptides from Protein
Hydrolysate of Skipjack Tuna Dark Muscles-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02948D, PaperLingting Meng, Yan Song, Bin Zheng, Yadong Zhao, Bingyuan Hong, Mingzhu Ma, Zhengshun Wen, Wenhua Miao, Yan Xu
To produce peptides with high DPP-IV inhibitory activity, neutrase was selected from five proteases and used to produce protein hydrolysate (NPH) from the dark muscles of skipjack tuna (Katsuwonus pelamis)....
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- The maca protein ameliorates DSS-induced colitis in mice by modulating the
gut microbiota and production of SCFAs-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03654E, PaperPing He, Yizhe Zhang, Ruyang Chen, Zhaoli Tong, Mengmeng Zhang, Hui Wu
Maca protein ameliorates DSS-induced colitis in mice by modulating the gut microbiota and production of SCFAs.
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- The amelioration of purified Pleurotus abieticola polysaccharide on
atherosclerosis in ApoE−/− mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02740F, PaperLei Xing, Fange Kong, Chunxia Wang, Lanzhou Li, Shichao Peng, Di Wang, Changtian Li
In this study, a polysaccharide known as PAPS2 was eluted from Pleurotus abieticola fruiting bodies using 0.1 M NaCl solutions. PAPS2 has a Mw of 19.64 kDa and its backbone...
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- 2’- fucosyllactose alleviates OVA-induced food allergy in mice by
ameliorating intestinal microecology and regulating the imbalance of
Th2/Th1 proportion-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03272H, PaperRuixin Kou, Jin Wang, ang li, yuanyifei wang, Dancai Fan, Bowei Zhang, Wenhui Fu, Jing-Min Liu, Hanyue Fu, Shuo Wang
Food allergy (FA) has become a prominent problem in public health. 2’-fucosyllactose (2’-FL) was reported to alleviate FA symptoms, while the regulatory mechanism is still unclear. This study evaluated the...
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- Recent advances in oral delivery systems of resveratrol: foreseeing their
use in functional foods-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03065B, Review Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Pedro M. Silva, Catarina Gonçalves, Lorenzo M. Pastrana, Manuel A. Coimbra, Antonio A. Vicente, Miguel A. Cerqueira
Herein, we review the current state-of-the-art on the use of micro- and nano-delivery systems, a possible solution to some of the drawbacks associated with the incorporation of resveratrol in foods.
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- Torreya grandis oil attenuates cognitive impairment in scopolamine-induced
mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03800A, PaperJiachen Ma, Tian Yuan, Yuqi Gao, Xiaoming Zeng, Zhigang Liu, Jinming Gao
The oil of Torreya grandis (TGO), a common nut in China, is considered to be a bioactive edible oil and has a great value in functional food development.
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- Ligilactobacillus salivarius CCFM 1266 modulates gut microbiota and
GPR109a-mediated immune suppression to attenuate immune checkpoint
blockade-induced colitis-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03867J, PaperShikai Yan, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen, Haiqin Chen, Qixiao Zhai
The wide application of immune checkpoint blockade (ICB) therapy is impeded by the development of ICB-induced colitis, a condition intricately linked to alterations in the gut microbiota. In our previous...
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- Effect of extract oil of fermented Tartary buckwheat on lipid-lowering,
inflammation modulation and gut microbial regulation in mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04117D, PaperXin Yang, Anran Zhu, Xuanchen Li, Shengling He, Yi Zhu, Anyan Wen, Likang Qin, Haiying Zeng
This study investigated the composition of Tartary buckwheat oil fermented by Monascus purpureus and extracted under supercritical CO2 conditions (FTBO), and evaluated its effects on lipid-lowering, inflammation modulation, and gut microbial...
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- Unveiling the Influence of Daily Dietary Patterns on Brain Cortical
Structure: Insights from Bidirectional Mendelian Randomization-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02879H, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cong Li, Zhe Chen, Shaqi He, Yanjing Chen, Jun Liu
Cognitive impairment is a significant concern in aging populations. This study utilized Mendelian randomization analysis to explore the impact of dietary habits and macro-nutrients on cortical structure. A bidirectional Mendelian...
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- Nutrikinetics and urinary excretion of phenolic compounds after a 16-week
supplementation with a flavanone-rich ingredient-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02820H, PaperJananee Muralidharan, Cindy Romain, Letizia Bresciani, Pedro Mena, Donato Angelino, Daniele Del Rio, Linda H. Chung, Pedro E. Alcaraz, Julien Cases
Metabolic fate of polyphenols in an acute and chronic setup.
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- Lactobacillus rhamnosus Probio-M9 alleviate OVA-sensitized food allergy
through modulating gut microbiota and its metabolism-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03321J, PaperJialu Shi, Pengfei Dong, Cheng Liu, Yan Xu, Mingzhu Zheng, Lei Cheng, Jin Wang, Vijaya G. S. Raghavan
Over the past few decades, food allergy has continued to rise, significantly burdening health, economy, and quality of life. However, current therapeutic strategies have limited efficacy and need to be...
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- Water extract of green tea attenuates alcohol-related hepatitis by
inhibiting liver inflammation and gut microbiota disturbance in mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03685E, PaperGuoqing Xia, Zixuan Li, Xiaodong Sheng, Zhong-Wen Xie, Cheng Zhang, Qian Fang, Tiantian Wang, Yulian Wang, baoming wu, Xiongwen Lv
Green tea is one of the main types of tea in China, and green tea has been widely consumed in the world. This study aims to investigate the potential mechanism...
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- Pediococcus acidilactici (pA1c®) alleviates obesity-related dyslipidemia
and inflammation in Wistar rats by activating beta-oxidation and
modulating gut microbiota-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO01651J, PaperDeyan Yavorov-Dayliev, Fermin Milagro, Miguel López-Yoldi, Iñigo Clemente, Jose Ignacio Riezu-Boj, Josune Ayo, María Oneca, Paula Aranaz
Due to the importance of gut microbiota in the regulation of energy homeostasis, probiotics have emerged as an alternative therapy to ameliorate obesity-related disturbances, including cholesterol metabolism deregulation, dyslipidemias and...
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- Effect of food matrix on the (Poly)phenols stability of different
plant-based meat products and their main ingredients after in vitro
gastrointestinal digestion-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03265E, PaperRaquel Lucas González, Vicente Diez Riquelme, Manuel Viuda-Martos, J. A. Perez-Alvarez, Elena Sanchez-Zapata, J. Fernandez-Lopez
The present study aimed to investigate the influence of the food matrix on the bioaccessibility of free and bound (poly)phenols in different plant-based foods. These plant-based matrices included two fresh...
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- Unveiling the flavone-solubilizing effects of α-glucosyl rutin and
hesperidin: probing structural differences through NMR and SAXS analyses-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03261B, PaperKazunori Kadota, Tero Kämäräinen, Fumie Sakuma, Keisuke Ueda, Kenjirou Higashi, Kunikazu Moribe, Hiromasa Uchiyama, Katsuhiko Minoura, Yuichi Tozuka
We are assessing flavone dissolution, by probing the interactions with Rutin-G and Hsp-G in aqueous solutions. Small-angle X-ray scattering and nuclear magnetic resonance analyses revealed that the solubilizing effect of Rutin-G was higher than that of Hsp-G.
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- In vitro protein digestibility of different soy-based products: Effect of
microstructure, physico-chemical properties and protein aggregation-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02410E, PaperMengdi Li, Jing Wang, Jiayu Zhang, Ying Lv, S. Guo, Paul Van der Meeren
This study investigates the effect of protein structure and food microstructure on in vitro protein gastrointestinal digestibility of different soy-based products, i.e. soy drink, reconstituted soy drink powder, firm tofu...
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- Naringin ameliorates liver fibrosis in zebrafish by modulating
IDO1-mediated lipid metabolism and inflammatory infiltration-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03858K, PaperMeng-chen Qin, Jun-jie Li, Yan-tao Zheng, Yun-jia Li, Yu-xue Zhang, Rou-xuan Ou, Wei-yi He, Jia-min Zhao, Su-tong Liu, Ming-hao Liu, Hai-yan Lin, Lei Gao
Liver fibrosis (LF) is an important reparative process in response to acute or chronic hepatic injury, which has the potential to advance towards cirrhosis and hepatocellular carcinoma.
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- Astaxanthin alleviates ganglioside metabolism disorder in the cortex of
Alzheimer's disease mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03223J, PaperZhigao Wang, Xiaoxu Wang, Yingxu Ma, Peixu Cong, Xincen Wang, Yu Song, Jie Xu, Changhu Xue
The present study analyzed the amelioration effect and mechanism of two kinds of astaxanthin on ganglioside metabolism in the cortex of APP/PS1 mice using the LC-MS strategy in combination with molecular biology.
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- Differences between soluble and insoluble undenatured type II collagen in
improving osteoarthritis in rats and their potential mechanisms-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02954A, PaperRong Xu, Yulan Du, Xiaomin Li, Xinliang Mao, Lin Zheng, Mouming Zhao
The differences in the improvement effects of SC II, IC II and celecoxib on MIA-induced osteoarthritis model rats were compared, and the results suggest SC II may be superior to IC II in improving osteoarthritis in rats.
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- Assessment of human inter-individual variability of phloretin metabolites
in urine after apple consumption. AppleCOR study-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02985A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Alba Macià, María-Paz Romero, Anna Pedret, Rosa Solà-Alberich, Mike Clifford, Laura Rubió-Piqué
Purpose: This study aimed to assess the inter-individual variation in phloretin absorption and metabolism and to seek possible phloretin metabotypes following apple snack consumption. Methods: The excreted phloretin metabolites in...
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- Inhibition of the NF-κB and mTOR targets by urolithin A attenuates
D-galactose-induced aging in mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03847E, PaperMengwei Zhang, Xin Tang, Bingyong Mao, Qiuxiang Zhang, Jianxin Zhao, Wei Chen, Shumao Cui
The dose-effect relationship between colonic perfusion of urolithin A and its anti-aging effect was investigated. Urolithin A inhibits NF-κB and mTOR targets to attenuate D-galactose-induced motor and cognitive decline.
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- Ameliorating the effect and mechanism of chitosan oligosaccharide on
nonalcoholic fatty liver disease in mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03745B, PaperJiahua Zhang, Jiayao Feng, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan Su
Previous studies have found that chitosan oligosaccharide (COST) can alleviate the clinical symptoms in non-alcoholic fatty liver disease (NAFLD) patients.
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- Anti-Helicobacter pylori activity and gastroprotective effects of human
stomach-derived Lactobacillus paragasseri strain LPG-9-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03562J, PaperBinyan Xu, Jingjing Kong, Yangfan Lin, Ziyu Tang, Jiaxin Liu, Zhenhui Chen, Weiseng Zeng, Yang Bai, Hongying Fan
The eradication of Helicobacter pylori is an urgent global issue. However, the traditional regimens have several limitations. Thus, we propose the idea of treating bacterial gastric disease with the objective...
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- The effect of oral supplements containing collagen peptides rich in X-Hyp
or X-Hyp-Gly compared with normal collagen hydrolysates on skin elasticity
and collagen holes: a randomised double-blind clinical study-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02873A, PaperLing Chen, Yuan Lv, Feifei Xu, F. Zhong
Collagen peptides enriched with X-Hyp or X-Hyp-Gly have demonstrated resistance to digestive and systemic enzymes, suggesting their potential for improved absorption efficiency and enhancement of skin properties. This study aimed...
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- Influence of in vitro gastrointestinal digestion and colonic fermentation
on carbonyls scavenging capacity of fiber-bound polyphenols from quinoa-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03000H, PaperJinxin Li, Hao Zhang, Ling Zhu, Gangcheng Wu, Hui Zhang
Whole grain insoluble dietary fiber (IDF) is a good source of bound-form polyphenols. In the present study, insoluble dietary fiber rich in bound polyphenols (BP-IDF) from quinoa, rye and wheat...
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- The binding mechanism of oat phenolic acid to whey protein and its
inhibition mechanism against AGEs as revealed using spectroscopy,
chromatography and molecular docking-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO02474A, PaperLezhen Dong, Yunzhen Zhang, Ying Li, Yahui Liu, Qin Chen, Lingyi Liu, Mohamed Farag, Lianliang Liu
Caffeic acid (CA) and gallic acid (GA) in oat phenolic acids were selected to assess their anti-glycosylation mechanisms using spectroscopy, chromatography and molecular docking.
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- Polar lipid-enriched milk fat globule membrane supplementation in maternal
high-fat diet promotes intestinal barrier function and modulates gut
microbiota in male offspring-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D2FO04026C, PaperHan Gong, Qichen Yuan, Min Du, Xueying Mao
MFGM-PL supplementation to HFD dams improved intestinal development in offspring at weaning via promoting intestinal proliferation, differentiation, tight junctions and modulating gut microbiota, mitigating HFD-induced gut dysbiosis in adulthood.
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- Akkermansia muciniphila attenuated lipopolysaccharide-induced acute lung
injury by modulating the gut microbiota and SCFAs in mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04051H, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jian Shen, Shuting Wang, He Xia, Shengyi Han, Qiangqiang Wang, Zhengjie Wu, Aoxiang Zhuge, Shengjie Li, Hui Chen, Longxian Lv, Yanfei Chen, Lanjuan Li
Gut microbiota is closely related to lipopolysaccharide (LPS)-induced acute lung injury (ALI). As was issued, Akkermansia muciniphila (A. muciniphila) maintained the intestinal barrier function and regulated the balance of reduced...
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- Epigallocatechin gallate alleviates osteoporosis by regulating gut
microbiota and serum metabolites in rats-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03233G, PaperXuebing Han, Yifeng Fu, Keyu Wang, Siying Li, Chang Jiang, Shuangshuang Wang, Zheng Wang, Gang Liu, Siwang Hu
Osteoporosis, one of the serious public health problems worldwide, can lead to degeneration of bone structure and increased risk of fractures. Epigallocatechin gallate (EGCG) is a natural product with potential...
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- Time-Restricted Feeding Alleviates Metabolic Implications of Circadian
Disruption by Regulating Gut Hormone Release and Brown Fat Activation-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02063K, Papersensen Chi, taoyuan Zhang, yu pan, shenghui Niu, lin Zhao, Zili Gu, Qi Liu, aishun Jin, wang Wang, shuai Tan
Individuals with rotating and night shift work are highly susceptible to developing metabolic disorders such as obesity and diabetes. This is primarily attributed to disruptions in the circadian rhythms caused...
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- Lactiplantibacillus plantarum CCFM8661 alleviates D-galactose-induced
brain aging in mice by the regulation of the gut microbiota-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03377E, PaperFeng Chen, Jiani Pan, Leilei Yu, Shunhe Wang, Chengcheng Zhang, Jianxin Zhao, Arjan Narbad, Qixiao Zhai, Fengwei Tian
Lactiplantibacillus plantarum CCFM8661 alleviates D-galactose induced aging in mice.
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- Association between whole-grain consumption and carotid
atherosclerosis: the Tianjin Chronic Low-Grade Systemic Inflammation and
Health (TCLSIH) cohort study-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO01921G, PaperGe Meng, Jiping Yao, Jiaoyang Li, Yeqing Gu, Hongmei Wu, Qing Zhang, Li Liu, Xuena Wang, Juanjuan Zhang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Kaijun Niu
Background: Whole-grain contain a range of beneficial nutrients,which are thought to play a role in the prevention of chronic diseases.However, the association between whole-grain consumption and the risk...
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- Liubao tea extract ameliorates ovalbumin-induced allergic asthma by
regulating gut microbiota in mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03470D, PaperShasha Guo, Yuxuan Shi, Anan Xu, Yuefei Wang, Ping Xu
Asthma, a chronic airway inflammation disease, has a complicated pathogenesis and limited therapeutic treatment. Evidence shows that intestinal microbiota exhibited crucial functional interaction with asthma syndrome. Liubao tea (LBT) is...
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- Alleviating Effect of Selenium-Enriched Lactobacillus plantarum 6076 on
Dextran Sulfate Sodium-Induced Colitis and Liver Inflammation in Mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03842D, PaperLixia Zan, Wenyi Zhang, shufeng shang, yuanyuan cui, Jinjin Pei, yahong yuan, Tianli Yue
The aim of this study is to investigate the alleviating effect of selenium-enriched Lactobacillus plantarum (SL) 6076 on colitis and liver inflammation induced by sodium dextran sulfate (DSS) in mice...
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- Branched-chain amino acid modulation of lipid metabolism, gluconeogenesis,
and inflammation in a finishing pig model: targeting leucine and valine-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03899H, PaperXinbo Zhou, Junjie Zhang, Jian Shen, Baojing Cheng, Chongpeng Bi, Qingquan Ma
Leucine and valine regulate lipid metabolism and gluconeogenesis as well as inflammation in a finishing pig model.
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- Mechanisms of interesterified fat digestibility in a food matrix using a
dynamic gastric model-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02963H, PaperLouise Salt, Giuseppina Mandalari, Mary Parker, Mahamoud Hussein, Charlotte Mills, Robert Gray, Sarah E.E. Berry, Wendy L. Hall, Peter J. Wilde
Industrially generated trans-fats have been linked with cardiovascular disease (CVD) and have thus been replaced by interesterified (IE) fats, in foods. Interesterification rearranges fatty acids on the glycerol backbone of...
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- Acute effects of drinks containing blackcurrant and citrus (poly)phenols
and dietary fibre on postprandial glycaemia, gut hormones, cognitive
-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03085G, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ana Pinto, Mark Hobden, Katherine Brown, Jonathan Farrimond, Darren Targett, Christopher P. Corpe, Peter Rory Ellis, Yvanna Todorova, Klaudia Socha, Shatha Bahsoon, Claudia Haworth, Morgane Marcel, Xirui Nie, Wendy L. Hall
(Poly)phenol (PP)-rich blackcurrant (BC) extracts reduce postprandial glucose concentrations. Combinations with other fruit (poly)phenols and fruit fibre may enhance the effect. This study investigated the acute effects of combinations of...
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- Effect of the phosphorylation structure in casein phosphopeptides on the
proliferation, differentiation, and mineralization of osteoblasts and its
mechanism-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03125J, PaperWanying Zhong, Jian He, Wen Huang, Guangling Yin, Guo Liu, Yong Cao, Jianyin Miao
Our study demonstrated that the highly phosphorylated casein phosphopeptide (residues 1-25) P5 efficiently promoted proliferation, differentiation, and mineralisation of MC3T3-E1 cells, and its phosphorylation structure also efficiently induced EGFR binding.
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- Nutritional composition, health-promoting effect, bioavailability, and
encapsulation of tree peony seed oil: a review-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO04094A, Review ArticleWen-Sen He, Qingzhi Wang, Liying Zhao, Jie Li, Junjie Li, Na Wei, Gang Chen
Tree peony is cultivated worldwide in large quantities due to its exceptional ornamental and medicinal value. In recent years, the edible value of tree peony seed oil (TPSO) has garnered...
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- The Source, Property, Extraction, Biosynthesis, Pharmacology, and
Application of Lycopene-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03327A, Review ArticleRongrui Wei, Qing-Yuan Lin, Mozili Adu, Hui-Lian Huang, Zhi-Hong Yan, Feng Shao, Guoyue Zhong, Zhong-Li Zhang, Zhipei Sang, Lan Cao, Qinge Ma
Lycopene is an important pigment with alkene skeleton from Lycopersicon esculentum, which is also obtained from some red fruits and vegetables. Lycopene is not only used in food field with...
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- The ability of supercritical CO2 carrot and pumpkin extracts to counteract
inflammation and oxidative stress in RAW 264.7 macrophages stimulated with
LPS or MDA-MB-231 cell-conditioned media-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03159D, PaperLuca Frattaruolo, Miriana Durante, Maria Stella Cappello, Anna Montefusco, Giovanni Mita, Anna Rita Cappello, Marcello Salvatore Lenucci
This study describes the effects of extraction method (SFE or CSE) and co-solvent composition (hempseed or flaxseed) on carrot and pumpkin extracts ability to counteract inflammation and oxidative stress in LPS-stimulated RAW 264.7 macrophages.
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- Epigallocatechin gallate (EGCG) alleviates the inflammatory response and
recovers oral microbiota in acetic acid-induced oral inflammation mice-
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Abstract:Food Funct., 2023, Advance Article
DOI : 10.1039/D3FO03107A, PaperYani Pan, Helin Lv, Xinyu Feng, Su Zhou, Hao Hu, Shuxi Chen, Yan Cheng, Fangyuan Fan, Shuying Gong, Ping Chen, Qiang Chu
EGCG alleviates acetic-acid-induced oral inflammation and induces beneficial changes in the oral microbiota. The anti-inflammatory effect of EGCG could be strongly correlated with its ability to reestablish the oral microbial balance.
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- Sea cucumber peptide positively regulates sexual hormones in male mice
with acute exhausted swimming: possibly through the Ca2+/PKA signaling
pathway-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03031H, PaperXianliang Luo, Wangxin Liu, Baodong Zheng, Yafeng Zheng, Minjie Zhao, Fengqin Feng, Ling Liu
Sea cucumber peptide (SCP) has been proven to have many active functions, but its impact and mechanism on testosterone synthesis are not yet clear. This study attempts to explore the...
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- Cooperative interactions between Veillonella ratti and Lactobacillus
acidophilus ameliorate DSS-Induced Ulcerative Colitis in Mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03898J, PaperNa Li, HeJing Wang, Huizhu Zhao, Mengyang Wang, Jin Cai, Yi Hao, Jia Yu, Yun Jiang, Xin Lü, Bianfang Liu
Veillonella and Lactobacillus species play vital roles in regulating a healthy gut environment through metabolic cross-feeding, influencing lactic acid and short-chain fatty acid (SCFA) levels. SCFAs are crucial for gut...
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- β-Carbolines Norharman and Harman change neurobehavior causing
neurological damage in Caenorhabditis elegans-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03732K, PaperLuyao Zhang, Jialu Liu, Bufan Xu, Di Wu, Yongning Wu, Guoliang Li
β-Carbolines Norharman and Harman, a class of heterocyclic aromatic amines (HAAs), are typical hazardous substance produced during the thermal processing of food. Compared to other HAAs, there have been limited...
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- Indole-3-acetamide from gut microbiota activated hepatic AhR and mediated
the remission effect of Lactiplantibacillus plantarum P101 on alcoholic
liver injury in mice-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03585A, PaperMengqi Wang, Xiaoyan Feng, Yu Zhao, Yuzhi Lan, Hengyi Xu
Alcoholic liver disease is a common condition caused by excessive alcohol consumption that can lead to lipid accumulation and inflammation. This study investigated the effects and mechanism of L. plantarum...
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- Fermented soybean foods (natto) ameliorate age-related cognitive decline
by hippocampal TAAR1-mediated activation of CaMKII/CREB/BDNF signaling
pathway in senescence-accelerated mouse prone 8 (SAMP8)-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO03987K, PaperYifeng Zheng, Mayu Yasuda, Mizuki Yamao, Toshiya Gokan, Yudai Sejima, Takanobu Nishikawa, Shigeru Katayama
Natto is a traditional fermented soybean-based food (natto) that has been an integral part of Japanese cuisine for several centuries. Although there have been extensive studies on the cognitive benefits...
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- Effect of different processed tomatoes on carotenoids releasing and
microbiota composition during in vitro gastrointestinal digestion and
colonic fermentation-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02849F, PaperXinyi Wu, Changan Zhu, Min Zhang, Shuwen Wang, J. Q. Yu, Jinhu Tian, Zhangjian Hu
Carotenoids in tomatoes pose significant health benefits to humans but with the disadvantages of the carotenoids from raw tomatoes not being easily absorbed for utilization. Thus, the study aimed to...
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- Protein-based nutritional strategies to manage the development of
diabetes: Evidence and challenges on human studies-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02466K, Review Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sergio Montserrat-de la Paz, Antonio D Miguel-Albarreal, Teresa Gonzalez-de la Rosa, Maria C. Millan-Linares, Fernando Rivero-Pino
Type 2 Diabetes Mellitus is one of the most prevalent diseases in modern societies, promoted by both genetic and environmental factors, such as nutritional habits. This metabolic disorder is characterized...
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- Black chokeberry (Aronia melanocarpa L.) polyphenols attenuates
obesity-induced colonic inflammation by regulating gut microbiota and
TLR4/NF-κB signaling pathway in high-fat diet-fed rats-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02177G, PaperYue Zhu, Peng-ju Cai, Han-chu Dai, Yu-hang Xiao, Chengli Jia, Ai-dong Sun
This study investigated the potential benefits of black chokeberry polyphenols (BCPs) supplementation on lipopolysaccharide (LPS)-stimulated inflammatory response in RAW264.7 cells and obesity-induced colonic inflammation in high-fat diet (HFD)-fed rats model....
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- Fucoxanthin alleviated myocardial ischemia and reperfusion injury through
inhibition of ferroptosis via NRF2 signaling pathway-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02633G, PaperJing Yan, Zehua Li, Yu Liang, Chaobo Yang, Wen Ou, Huaqiang Mo, Min Tang, Deshu Chen, Chongbin Zhong, Dongdong Que, Liyun Feng, Hua Xiao, Xudong Song, Pingzhen Yang
Background: Myocardial ischemia and reperfusion injury (MIRI) is an severe complication during revascularization therapy in patients with myocardial infarction. It is urgent to find more therapeutic target to MIRI. Recently,...
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- Oleanolic acid, a small-molecule natural product, inhibits ECM
degeneration in osteoarthritis by regulating Hippo/YAP and Wnt/β-catenin
pathways-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO01902K, PaperTianwen Ma, Hongri Ruan, Liangyu Lv, Chengwei Wei, Yue Yu, Lina Jia, Xiaopeng Song, Jiantao Zhang, Yanan Li
Over the past few decades, osteoarthritis (OA) has been a major health problem worldwide. It is imminent to develop new, effective, and safe drugs to treat OA. There are many...
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- Dietary Lactobacillus rhamnosus GG extracellular vesicles enhance
anti-PD-1 immunotherapy efficacy against colorectal cancer-
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Abstract: Food Funct., 2023, Accepted Manuscript
DOI : 10.1039/D3FO02018E, PaperShun Lu, Jing Xu, Zihao Zhao, Yuheng Guo, Hanwen Zhang, Peter W. Jurutka, Dechun Huang, Chongjiang Cao, Shujie Cheng
There is a need to explore combination therapy to improve the efficacy of immunotherapy for colorectal cancer through food probiotics. In this study, extracellular vesicles (EV) derived from Lactobacillus rhamnosus...
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