JournalTOCs

Food & Function
Journal Prestige (SJR): 1.209

Citation Impact (citeScore): 4
Number of Followers: 6

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 2042-6496 - ISSN (Online) 2042-650X
Published by RSC

[50 journals]

Effect of dark sweet cherry (Prunus avium) supplementation on the fecal
microbiota, metabolic endotoxemia, and intestinal permeability in obese
subjects: a single-blind randomized trial
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01650E, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shirley Arbizu, Susanne Mertens-Talcott, Stephen Talcott, Giuliana Noratto
  This single blind placebo-controlled study investigated the influence of dark sweet cherries (DSC) consumption on obesity-related dysbiosis, metabolic endotoxemia, and intestinal permeability. Participants (> 18 years old, BMI: 30-40 kg/m2)...
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Arachidonic acid enhances hepatocyte bile acid uptake and alleviates
cholestatic liver disease by upregulating OATP1 expression.
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02158D, PaperYanlu Ma, Chen Zou, Yilan Yang, Miao Fang, Yunfeng Guan, Jianqi Sun, Yueqiu Gao, Zhi Shang, Xin Zhang
  Cholestatic liver disease is caused by disorders of bile synthesis, secretion, and excretion. Over the long term, progressive liver cell damage from the disease evolves into liver fibrosis and cirrhosis,...
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High-throughput discovery of umami peptides from pork bone and elucidation
of their molecular mechanism for umami taste perception
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO03145H, PaperYuxiang Gu, Yajie Niu, Jingcheng Zhang, Baoguo Sun, Zunying Liu, Xiangzhao Mao, Yuyu Zhang
  This study endeavored to high-throughput identify umami peptides from pork bone.
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Neltuma nigra cotyledon and seed flour: nutritional, phytochemical, and
techno-functional characterization and nutraceutic potential of
polyphenolic enriched extract
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01827C, PaperFlorencia Cattaneo, Ivana Fabiola Rodríguez, Iris Catiana Zampini, Alberto Burgos-Edwards, Guillermo Schmeda-Hirschmann, María Inés Isla
  Neltuma nigra seed and cotyledon flours were prepared and characterized.
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Raw and heat-treated quinoa protein protects against glucose metabolism
disorders in high-fat diet (HFD)-induced mice by reshaping gut microbiota
and fecal metabolic profiles
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02904F, PaperZijian Dai, Han Wang, Qun Shen, Yichen Hu, Yong Xue
  Quinoa protein improved glucose metabolism and protected against alterations in gut microbiota induced by a chronic HFD. In addition, it increased the abundance of beneficial bacteria, followed by an increase in potentially beneficial metabolites.
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Blue mussel (Mytilus edulis) water extract ameliorates intestinal immune
response in high-fat diet–streptozotocin-induced diabetic mice
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D3FO04639G, PaperSabri Sudirman, Yi-Yuh Hwang, Chia-Hung Su, Ting-Yu Lu, Hsiang-Ping Kuo, Deng-Fwu Hwang, Zwe-Ling Kong
  Mytilus edulis water extract enhances antioxidant activity, increases interleukin-10 concentration and natural killer cell activation and improves the phagocytic capacity of monocytes and the proliferative capacity of lymphocytes.
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A high-fat diet induced depression-like phenotype via hypocretin-HCRTR1
mediated inflammation activation
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  Abstract: Food Funct., 2024, 15,8661-8673
  
  DOI : 10.1039/D4FO00210E, PaperJingyi Dong, Jinghui Zhang, Shangping Cheng, Bin Qin, Kangyu Jin, Bing Chen, Yuyan Zhang, Jing Lu
  HFD tips gut microbiota balance via the gut-brain axis perturbs cerebral equilibrium, increases hypocretin levels, and triggers microglial activation. This leads to inflammation and may cause mental disorders like depression and anxiety.
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Improving insulin resistance by sulforaphane via activating the
Bacteroides and Lactobacillus SCFAs–GPR–GLP1 signal axis
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  Abstract: Food Funct., 2024, 15,8644-8660
  
  DOI : 10.1039/D4FO01059K, PaperSicong Tian, Yiting Lei, Fangling Zhao, Jiawen Che, Yanhong Wu, Peng Lei, Yea Eun Kang, Yujuan Shan
  SFN alleviated IR via the Bacteroides and Lactobacillus-SCFAs–GPR41/43-GLP1 axis and protected the intestinal mucosal barrier, thereby, reducing the inflammatory response.
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Food Nanotechnology: Opportunities and Challenges
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02119C, Review ArticleZhiyu Yan, Songyi Lin, Fanghan Li, Jiaxin Qiang, Simin Zhang
  Food nanotechnology, which applies nanotechnology into food system ranging from food production to food processing, packaging, transportation, is producing tremendous opportunities for conventional food science and industry innovation and improvement....
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The bioavailability of polyphenols following acute consumption of
pigmented barley and wheat
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01162G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Borkwei Ed Nignpense, Nidhish Francis, Christopher Blanchard, Abishek Santhakumar
  Polyphenols from pigmented cereal grains exert health-promoting effects but data on their bioavailability are limited.
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Sensory improvement and antioxidant enhancement in silver carp hydrolysate
using prebiotic oligosaccharides: Insights from the Maillard reaction
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01284D, PaperPeipei Dou, Kai Wang, Ning Ding, Yanyan Zheng, Hui Hong, Huaigao Liu, Yuqing Tan, Yongkang Luo
  Our previous studies have highlighted the potential of silver carp hydrolysate (SCH) in managing chronic diseases. Unfortunately, its fishy smell and bitter taste limited consumer acceptance. Prebiotic oligosaccharides are often...
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Exercise-promoted Adiponectin Secretion Activates Autolysosomes to Protect
the Liver of ApoE-/- mice from a High-fat diet
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02984D, PaperWeijia Wu, Ye Jian, Shunling Yuan, Xuan Li, Yingzhe Tang, Fanqi Zeng, Yiyang Wang, Wenjing Liu, Yirong Wang, Zhe Zhao, Wenfeng Liu
  The function of fat is a "double-edged sword", it is a necessary substance for the body, but the long-term intake of excessive fat will cause obesity, and the liver will...
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Blueberry extract attenuates DSS-induced inflammatory bowel disease in
mice through inhibiting ER stress-mediated colonic apoptosis in mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00194J, PaperJun Wang, Xin-Yu Wang, Zhong-Yu Yuan, Xiao-Han Wang, Yu-Ying Guan, Ji-Xiao Zhu, Wei-Feng Huang, Qing Liu, Guang-Hui Xu, Litao Yi
  Inflammatory bowel disease (IBD) is a chronic, debilitating condition with limited therapeutic options. Dietary components like blueberry have emerged as potential modulators of inflammation and tissue repair in gastrointestinal diseases....
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Lacticaseibacillus casei- and Bifidobacterium breve-fermented red pitaya
promotes beneficial microbial proliferation in the colon
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02352H, PaperLi Cao, Mengxi Wan, Zhixing Xian, Yongqiang Zhou, Lihong Dong, Fei Huang, Dongxiao Su
  Red pitaya has been demonstrated to strongly inhibit α-glucosidase activity; however, the impact of red pitaya fermentation by probiotic bacteria on α-glucosidase inhibition remains unclear. In this study, six strains...
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Chemistry, bioactivities, structure-activity relationship, biosynthesis
and metabolisms of prenylated flavonoids in Moraceae plants
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02688H, Review ArticleNing Li, Wenjing Lu, Hui Ren, Zhiyong Chen
  Plants from Moraceae are globally popular as they represent a valuable resource with wide applications in food, health-care products, and other fields. Prenylated flavonoids are important active components in Moraceae....
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Typical structural characteristics and hepatoprotective effects of novel
high Fischer ratio oligopeptides from Antarctic krill on acute alcoholic
liver injury
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02609H, PaperYan Sun, Huiru Shen, Chaozhong Fan, Cili Wang, Yan Fan, Li Hao, Qiaoji Tian, Hu Hou
  High Fischer ratio oligopeptides derived from Antarctic krill (HFOPs-AK) were screened, and their typical structure, separation and purification, hepatoprotective effects and potential mechanisms were investigated.
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Effect of digested chia seed protein on the gut microbiota and colon
morphology of mice fed a high-saturated-fat diet
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02199A, PaperMariana Grancieri, Vinícius Parzanini Brilhante de São José, Renata Celi Lopes Toledo, Thaisa Agrizzi Verediano, Cintia Sant'Ana, Haira Guedes Lúcio, Elvira Gonzalez de Mejia, Hércia Stampini Duarte Martino
  The consumption of DTP from chia seed improved the gut microbiota composition and mucosal integrity minimizing the negative effects of a diet rich in saturated fat.
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Unveiling the anti-inflammatory potential of 11β,13-dihydrolactucin for
application in inflammatory bowel disease management
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01446D, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Melanie S. Matos, María Ángeles Ávila-Gálvez, Antonio González-Sarrías, Nuno-Valério Silva, Carolina Lage Crespo, António Jacinto, Ana Teresa Serra, Ana A. Matias, Cláudia Nunes dos Santos
  11β,13-Dihydrolactucin, a sesquiterpene lactone found in chicory, presents promising anti-inflammatory potential in complementary in vitro and in vivo models of intestinal inflammation, acting at several levels of the cellular inflammatory response.
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Allantoin Ameliorates Dopaminergic Neuronal Damage in MPTP-Induced
Parkinson’s Disease Mice via Regulating Oxidative Damage, Inflammation,
and Gut Microbiota Disorder
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02167C, Papershuo yang, Xiaojia Sun, Dianfeng Liu, Yiming Zhang, Xiyu Gao, Jiangmei He, Mingchi Cui, Shoupeng Fu, Dewei He
  Parkinson’s disease (PD) is a chronic progressive neurodegenerative disease that often occurs in older people. Neuroinflammation and oxidative stress are important factors in the development of PD. Gastrointestinal dysfunction is...
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Effects of konjac glucomannan intake patterns on glucose and lipid
metabolism of obese mice induced by high fat diet
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02442G, PaperSijia Zhu, Jiyu Yang, Pengkui Xia, Sha Li, Qi Wang, Kaikai Li, Bin Li, Jing Li
  Konjac glucomannan (KGM) is a dietary fiber supplement that exhibits multiple biological activities, including weight control and regulation of glucose and lipid metabolism. Currently, KGM intake patterns in practical applications...
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Sulfonation metabolism in gut microbiota is the main metabolic pathway of
cholesterol in hypercholesterolemic mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02312A, PaperGuangtao Yan, Zehui Qin, Aitong Liu, Ziwei Huang, Xinhong Wang, Shanli Zhang, Xiaolin Xie, Xiaoqi Huang, Jiannan Chen, Yucui Li, Xie Qingfeng, Yu-Hong Liu, Zi-Ren Su, Jianhui Xie
  The interactions between dietary cholesterol and intestinal microbiota strongly affect host health. Sulfonation is a major conjugating pathway responsible for regulating the chemical and functional homeostasis of endogenous and...
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Pea protein hydrolysate stimulates GLP-1 secretion in NCI-H716 cells via
simultaneously activating sensing receptors CaSR and PepT1
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01290A, Papermingkai zhang, Ling Zhu, Hui Zhang, Xingguo Wang, Gangcheng Wu
  Glucagon-like peptide-1 (GLP-1) plays a crucial in regulating glucose homeostasis by stimulating insulin secretion and suppressing glucagon release. Our previous study observed that pea protein hydrolysate (PPH) exhibited the function...
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Effect of Heat-treated Flaxseed Lignan Macromolecules on the Interfacial
Properties and Physicochemical Stability of α-linolenic Acid-Enriched O/W
Emulsions
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02663B, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chen Cheng, Xiao Yu, Fenghong Huang, Lei Wang, Zhenzhou Zhu, Jing Yang, Pen Chen, Qianchun Deng
  Flaxseed Lignan Macromolecules (FLM) is an important polyphenol in flaxseed with interfacial adsorption behavior. However, FLM is easily degraded during thermal treatment in emulsions which further influence its interfacial properties...
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The therapeutic effect and possible mechanisms of alginate oligosaccharide
on metabolic syndrome by regulating gut microbiota
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02802C, Review ArticleJingyi Wang, Tong Dai, Ziheng Zhang, Qingfeng Zhang, Jingtong Yao, Lijing Wang, Ningning He, Shangyong Li, Zixuan Zhang
  Metabolic syndrome (MetS) is a diseased condition incorporating the abnormal accumulation of various metabolic components, including overweight or abdominal obesity, insulin resistance and abnormal glucose tolerance, hypertension, atherosclerosis, or dyslipidemia....
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A Systematic Review of Dietary and Circulating Carotenoids and Liver
Disease
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO03082F, PaperBihuan HU, Jing Sui, Hui Xia, Ying Wang, Lihua Li, Daochen Gong, Zixuan Zhu, Wang Liao, Guiju Sun
  Background: Due to the high incidence of liver disease and the severity of adverse outcomes, liver disease has become a serious public health problem, bringing a huge disease burden to...
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Predicting structure-targeted natural therapeutics for middle-aged and
elderly Asians with myocardial infarction: Insights from genetic
variations and bioinformatics-integrated deep learning analysis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00591K, PaperJunyu Zhou, Heng Yuan, Sunmin Park
  Myocardial infarction (MI) is a significant global health issue. Despite advances in genome-wide association studies, a complete genetic and molecular understanding of MI is still elusive and needs to be...
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Chemical analysis of freeze-dried seeds of Stenocereus stellatus (White
tunillo) and evaluation of the prediabetes reversion effect in an
experimental model in female Wistar rats.
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01908C, PaperVicente CASTREJÓN Castrejón Téllez, Víctor Hugo Oidor-Chan, Andrea Brenda Arellano-Mauricio, Leonardo del Valle-Mondragón, Luz Ibarra-Lara, Claudia Ponce, Emma Rodríguez-Maldonado, Jose Alberto Mendoza-Espinoza, Francisco Cruz-Sosa, Veronica Guarner-Lans, Mariana M. Patlan, Fernando Diaz de León
  Prediabetes is defined as a state of moderate hyperglycemia. Here, we used a freeze-dried seeds of Stenocereus stellatus (White tunillo) as a possible therapeutic strategy for the treatment of prediabetes....
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Comparative transcriptomics reveals the mechanism of antibacterial
activity of fruit-derived dihydrochalcone flavonoids against Porphyromonas
gingivalis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02854F, PaperDesheng Wu, Lisha Hao, Xiaohan Liu, Xiaofeng Li, Guanglei Zhao
  Porphyromonas gingivalis causes various health issues through oral infections. This study investigates the antibacterial activities of the food-derived dihydrochalcone flavonoids against Porphyromonas gingivalis and their mechanisms of the antibacterial actions...
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Ginsenoside compound K alleviates D-galactose-induced mild cognitive
impairment by modulating gut microbiota-mediated short-chain fatty acid
metabolism
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO03216K, PaperXiaojun Yan, Xue Bai, Rongzhan Fu, Zhiguang Duan, Wen Zeng, Chenhui Zhu
  Ginsenoside compound K ameliorates D-galactose-induced mild cognitive impairment by modulating the gut microbiota, increasing the abundance of beneficial Akkermansia, regulating propionate metabolism, and inhibiting the TLR4/NF-κB signaling pathway.
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Comment on “Olive oil intake and cardiovascular disease, cancer, and
all-cause mortality: a systematic review and dose–response meta-analysis
of prospective cohort studies” by Y. Ke, H. Fan, Y. Zhao, X. Fu, M.
Wang, Y. Gao, Y. Chen, W. Huo, W. Zhang, L. Wang, Y. Wu, X. Li, D. Zhang,
F. Hu, M. Zhang, L. Sun, J. Lu and D. Hu, Food &Function, 2024, D3FO05246J
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01826E, CommentYang Zhao, Qian Wang
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New findings in the metabolism of the saffron apocarotenoids, crocins and
crocetin, by the human gut microbiota
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02233E, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Carlos Garcia, david beltran, Maria Dolores Frutos-Lisón , M. T. Garcia-Conesa, Francisco Tomas-Barberan, Rocio Garcia-Villalba
  The main constituents of saffron are the apocarotenoids crocin and crocetin, present in the stigmas. Numerous healthy properties, especially those related to the effects on the central nervous system, have...
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Signaling pathways involved in the anti-hyperglycemic effect of Raspberry
Ketone in zebrafish by integrative transcriptome and metabolome analysis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01675K, PaperXinliang Zhu, Dengcai Zhang, Yong Wang, Chuangxin Wang, Xiaoxiao Liu, Yicong Niu
  Hyperglycemia leads to increased oxidative stress in mitochondria, abnormal activation of intracellular inflammatory signals, and mediate multiple dysfunctions. Raspberry ketone (RK) is an aromatic phenolic compound found in many plants...
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Recent advances in nanodelivery systems of resveratrol and their
biomedical and food applications: a review
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D3FO03892K, Review ArticleYanan Song, Junjia Zhang, Ling Zhu, Hui Zhang, Gangcheng Wu, Tongtong Liu
  The recent advances of resveratrol nano delivery systems, the advantages and potential limitations, as well as their associated applications in biomedical and food.
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Immunoproteomic profile of Malus domestica in Mexican pediatric patients.
Evidence of new allergen prospects
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO00064A, PaperAngélica Torres-Arroyo, Carla Toledo-Salinas, Juan Martínez-Aguilar, Alberto Fernández-Molina, Aramiz López-Durán, Sara T. Méndez, David Alejandro Mendoza-Hernández, Horacio Reyes-Vivas
  Background: Apple (Malus domestica) is a fruit commonly associated with allergic oral symptoms in the Mexican pediatric population; however, knowledge of its allergenic proteins is limited.
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Differential Effects of Milk, Yogurt, and Cheese on Energy Homeostasis and
Brown Adipose Tissue Phenotype in High-Fat Diet-Induced Obese Mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02201G, PaperEmad Yuzbashian, Dineli N Fernando, Siegfried Ussar, C.B. Chan
  Aim: We hypothesized that milk, yogurt, and cheese have differential impacts on energy expenditure (EE) and obesity in mice fed a high-fat diet (HFD). Methods: C57BL/6 mice (n = 16...
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Preparation of Lactobacillus rhamnosus ATCC 7469
microencapsulated-lactulose synbiotic and its effect on equol production
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02690J, PaperXiaoying Wang, Yuhao Ma, Yingqing Liu, Jiuyan Zhang, Weiliang Jiang, Xiang Fang, Li Wang
  Equol is a highly active product of soy isoflavones produced by specific bacteria in the human or animal colon. However, equol production is influenced by differences in the flora carried...
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Unveiling the Dynamic Processes of Dietary Advanced Glycation End-Products
(dAGEs) in Absorption, Accumulation, and Gut Microbiota Metabolism
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01545B, PaperYi Wu, Yuqi Yang, Yanhong Zhong, Yongtai Wu, Zhenhui Zhang, Zichen Yan, Bingxin Liu, Wei Wang
  This study delves into the dynamics of dietary Advanced Glycation End-products (dAGEs) on host health and gut microbiota. Using 13C-labeled Carboxymethyllysine (CML) bound casein, we identify bound AGEs as the...
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Quercetin ameliorates celiac-related intestinal inflammation caused by
wheat gluten through modulating oxidative stress, Th1/Th2/Treg balance,
and intestinal microflora structure
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO03025G, PaperTian Yu, Yiting Xie, Zhongliang Wang, Jingjing Li, Yunpeng Shen, Juanli Yuan, Jinyan Gao, Md. Fakruddin, Yong Wu, Hongbing Chen
  Celiac disease is a chronic inflammatory autoimmune disease of the small bowel, and about 1% of the world’s population is afflicted with celiac disease. Until now, the most efficient treatment...
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Circulating fatty acids and risk of severe non-alcoholic fatty liver
disease in the UK biobank: a prospective cohort of 116,223 individuals
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01182A, PaperPan Zhuang, Yang Ao, Xiaohui Liu, Hao Ye, Haoyu Li, Xuzhi Wan, Yu Zhang, Jingjing Jiao
  Fatty acid (FA) metabolism plays an important role in the development of nonalcoholic fatty liver disease (NAFLD). However, data on the relation of circulating FAs with NAFLD risk are limited....
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Docosahexaenoic Acid inhibits the invasion and migration of colorectal
cancer by reversing EMT through the TGF-β1/Smad signaling pathway
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02346C, PaperYi-Ling Jiang, Xue Li, Ya-Wen Tan, Yu-Jing Fang, Kai-Yan Liu, Yi-Fan Wang, Ting Ma, Qing-Jian Ou, Cai-Xia Zhang
  The primary cause of mortality in colorectal cancer (CRC) patients is tumor metastasis. Epithelial-mesenchymal transition (EMT) stands out as a crucial factor promoting the metastasis of CRC. Previous findings suggest...
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An untargeted metabolomics approach applied to the study of the
bioavailability and metabolism of three different bioactive plant extracts
in human blood samples.
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01522C, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.María del Carmen Villegas Aguilar, María de la Luz Cádiz-Gurrea, María Herranz López, Enrique Barrajón Catalán, David Arráez-Román, Álvaro Fernández-Ochoa, Antonio Segura-Carretero
  Advances in the understanding of bioavailability and metabolism of bioactive compounds have been achieved primarily through targeted or semi-targeted metabolomics approaches using the hypothesis of potential metabolized compounds. The recent...
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Correction: Attenuation of metabolic syndrome in the ob/ob mouse model by
resistant starch intervention is dose dependent
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO90078B, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anqi Wang, Min Liu, Wenting Shang, Jinguang Liu, Zhen Dai, Padraig Strappe, Zhongkai Zhou
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Tannin-based supplementation influences gut microbiota composition and
activity in IBS-D patients with a potential impact on symptoms: a pilot
study
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02236J, PaperSilvia Molino, Alberto Lerma-Aguilera, María Marta Piskorz, Fabiana López Mingorance, Juan M. Montero, Tatiana Uehara, Harumi Hashimoto, Esteban González Ballerga, Jorge A. Olmos
  A preliminary, quasi-experimental, before-after and prospective study was conducted on 28 IBS-D patients to test the effect of a tannin-based supplement on the composition and activity of the microbiota, after 8 weeks of treatment.
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Effect of dietary fibre on cognitive function and mental health in
children and adolescents: a systematic review and meta-analysis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02221A, Review ArticleMingyue Yang, Chenxi Cai, Zhongmin Yang, Xve Wang, Guiling Li, Jian Li, Jingwen Liu, Zhengxiao Zhang
  Objective: The purpose of this study is to investigate the impact of dietary fibre on the mental health and cognitive function of children and adolescents. Methods: All interventional and observational...
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Targeted hydrothermally induced cell biopolymer changes explain the in
vitro digestion of starch and proteins in common bean (Phaseolus vulgaris)
cotyledons
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO00734D, PaperErick O. Okelo, Irene Wainaina, Dorine Duijsens, Arnold Onyango, Daniel Sila, Tara Grauwet, Marc E. G. Hendrickx
  Digestion of protein and starch in pulses is a consequence of the interplay of both extrinsic and intrinsic factors which influence their level of encapsulation and physical state, and therefore, their accessibility by the digestive enzymes.
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Towards more sustainable cooking practices to increase the
bioaccessibility of colourless and provitamin A carotenoids in cooked
carrots
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02752C, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ana M. Benítez-González, Carla M. Stinco, Francisco J. Rodríguez-Pulido, Isabel M. Vicario, Antonio J. Meléndez-Martínez
  The effect of different cooking methods (boiling, baking, steaming and microwaving) on the colour and texture of carrots, and on carotenoid bioaccessibility, was investigated to identify the more “sustainable cooking” methods.
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Construction of chlorogenic acid nanoparticles for effective alleviation
of ulcerative colitis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02122C, PaperShumeng Hu, Runan Zhao, Tao Chen, Xuesong Chi, Yangjing Li, Di Wu, Bei-Wei Zhu, Jiangning Hu
  The onset and progression of ulcerative colitis (UC) are intricately linked to the worsening of intestinal inflammation, an imbalance in oxidative stress, and impairment of the intestinal mucosal barrier. Although...
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Bifidobacterium animalis subsp. lactis CCFM1274 relieved allergic asthma
symptoms by modifying intestinal tryptophan metabolism in mice
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01079E, PaperHongchao Wang, Yuan He, Danting Dang, Ling Feng, Liming Huang, Jianxin Zhao, Shourong Lu, Wenwei Lu
  CCFM1274 remodeled intestinal tryptophan metabolism in mice and contributed to the improvement of allergic asthma through downregulating the levels of OVA-sIgE, IL-10 and IL-17 in BALF and upregulating the relative abundance of Bifidobacterium.
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Correction: Theobromine supplementation in combination with a low-calorie
diet improves cardiovascular risk factors in overweight and obese subjects
with metabolic syndrome: a randomized controlled trial
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO90077D, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Elham Sharifi-Zahabi, Nayebali Rezvani, Fatemeh Hajizadeh-Sharafabad, Fatemeh Sadat Hosseini-Baharanchi, Farzad Shidfar, Mehrali Rahimi
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The alleviative effects of viable and inactive Lactobacillus paracasei
CCFM1120 against alcoholic liver disease via modulation of gut microbiota
and the Nrf2/HO-1 and TLR4/MyD88/NF-κB pathways
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02592J, PaperBen Niu, Yingxuan Feng, Xu Cheng, Yue Xiao, Jianxin Zhao, Wenwei Lu, Fengwei Tian, Wei Chen
  Probiotics can alleviate alcoholic liver disease.
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Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated
HFD-induced impaired glucose tolerance via small intestinal barrier and
hepatic glucose metabolism
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02805H, PaperZehua Liu, Yijie Yang, Yi Xu, Zhaowan Zhang, Ruoxin Tang, Jianshen Liu, Hongxin Jiang, Renyong Zhao
  Highland barley is a natural source for the development of phenolic compounds that showed potential of preventing type 2 diabetes, which is important for the agricultural and industrial utilization of...
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Effect of transglutaminase-catalyzed glycosylation on the allergenicity of
tropomyosin in Perna viridis food matrix
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02305F, PaperDongxiao Li, Xin-Rong He, Fa-Jie Li, Yang Yang, Meng Liu, Qing-Mei Liu, Lianzhong Luo, Gui-Xia Chen, Guangming Liu
  Food allergy is one of the hot issues in the field of food safety, there have been a lot of concerns on how to reduce the allergenicity of food allergens....
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Recent research on the physicochemical properties and biological
activities of quinones and their practical applications: a comprehensive
review
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02600D, Review ArticleMingyu Dong, Xiaozhi Ming, Tianyu Xiang, Nianjie Feng, Mengyun Zhang, Xurui Ye, Yi He, Mengzhou Zhou, Qian Wu
  Quinones represent a class of crude organic compounds ubiquitously distributed in nature. Their distinctive quinone-type structure confers upon them unique properties and applications. The quinones demonstrates significant biological activities, including...
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Characterization, mechanisms, structure-activity relationships, and
antihypertensive effects of ACE inhibitory peptides: rapid screening from
sufu hydrolysate
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02834A, PaperJianfei Li, Haohan Hu, Feng Chen, Chenying Yang, Wanzhou Yang, Yuexin Pan, Xiaodong Yu, Qiyi He
  This study investigates the characterization, mechanisms of action, structure-activity relationships, and in vivo antihypertensive effects of ACE inhibitory peptides derived from sufu hydrolysate following simulated gastrointestinal digestion. Sufu was enzymatically...
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Lactobacillus-derived indole derivatives ameliorate intestinal barrier
damage in rat pups with complementary food administration
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02230K, PaperArong Wang, Cheng Guan, Tieqi Wang, Guangqing Mu, Yanfeng Tuo
  The consumption of complementary foods can bring about diarrhea and intestinal barrier dysfunction in rat pups.
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Cinnamon extracts, trans-cinnamaldehyde and trans-cinnamic acid inhibits
HDAC 1 activity
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02764G, PaperHalil Koyu, Huseyin Istanbullu, Sinem Ezgi Turunc Ozoglu, Tijen Kaya Temiz
  Cinnamon (Cinnamomum cassia (L.) J.Presl) barks has been a regularly consumed dietary additive due to its rich flavor. Beyond nutritional aims, cinnamon components may present co-benefits during lifelong usage. Discovery...
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Oral aged garlic (Allium sativum) alleviates ulcerative colitis in mice by
improving gut homeostasis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO03105A, PaperDeping Han, Xuke Guan, Fengxia Zhu, QING YANG, Dingding Su
  Aged garlic, obtained by heating raw garlic (Allium sativum) under high temperature and controlled humidity for a period, possesses a wide range of bioactivities, but its role in ulcerative colitis...
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Monascus-fermented quinoa alleviates hyperlipidemia in mice by regulating
the amino acid metabolism pathway
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00930D, PaperZhiwei Huang, Lichen Chen, Lishi Xiao, Yanfang Ye, Wenlan Mo, Zhenghuai Zheng, Xiangyou Li
  Monascus has the ability to produce secondary metabolites, such as monacolin K (MK), known for its physiological functions, including lipid-lowering effects. Widely utilized in industries such as health food and...
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Comparison of Three Sourdough Postbiotics on High-Fat Diet-Induced
Intestinal Damage
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02948H, PaperYujuan Yu, Min Zhou, Faizan A. Sadiq, Pengli Hu, Feng Gao, Juanxia Wang, Aowen Liu, Yue Liu, Haili Wu, Guohua Zhang
  There is significant interest in using postbiotics as an intervention strategy to address obesity. This study assesses the efficacy of postbiotics derived from different sourdough strains (Lactiplantibacillus plantarum LP1, LP25,...
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S-methyl-L-cysteine targeting MsrA attenuates Ang II-induced oxidative
stress and atrial remodeling via p38 MAPK signaling pathway
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO03078H, PaperBeibei Xu, Yinli Xu, Wenpu Ren, Shan Meng, Tao Hong, Zijun Cao, Xiong Xiao, Xiaodong Guo, Liming Yu, Jikai Zhao, Huishan Wang
  Atrial fibrillation (AF) is the most prevalent sustained tachyarrhythmia in patients undergoing cardiovascular diseases. Recently, oxidative stress is considered an important contributor to AF. Therefore, antioxidant therapies for AF have...
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Construction and characterization of stable multi-species biofilms formed
by nine core gut bacteria on wheat fiber
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01294A, PaperTing Zhang, Yue Xiao, Hongchao Wang, Jinlin Zhu, Wenwei Lu, Hao Zhang, Wei Chen
  Nine core gut bacteria (M9) can successfully form stable and complex multi-species biofilms on wheat fiber through a dynamic fermentation method.
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Probiotics suppress LL37 generated rosacea-like skin inflammation by
modulating TLR2/MyD88/NF-κB signaling pathway
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO03083D, PaperXinyue Qi, Yiran Xiao, Xinfeng Zhang, Zhenlin Zhu, Hongyan Zhang, Jing Wei, Zhixiang Zhao, Ji Li, Tingtao Chen
  Rosacea, a chronic inflammatory dermatological condition characterized by facial erythema and pustules. Recent investigations have delved into the interplay between the gut microbiota and rosacea pathogenesis, unveiling promising avenues for...
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Supplementation with Bifidobacterium animalis subsp. lactis MH-022 for
Remission of Motor Impairments in a 6-OHDA-Induced Parkinson's Disease Rat
Model by Reducing Inflammation, Reshaping the Gut Microbiome, and
Fostering Specific Microbial Taxa
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02039A, PaperShu-Ping Tsao, Tu-Hsueh Yeh, Ya-Tin Lin, Chun-Hsu Pan, Yuan Lee, Chieh-Hsi Wu, Hui-Yu Huang
  Inflammation significantly influences the degeneration of dopaminergic neurons in Parkinson’s disease (PD), which is potentially intensified by associated gut dysbiosis. The therapeutic potential of probiotics, due to their antioxidant, anti-inflammatory,...
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Liver-gut axis including metabolomics and intestinal flora to discover the
protective effects of Kiwifruit seed oil on CCl4-induced acute liver
injury
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02106A, PaperXuting Hao, Wenjing Guo, Fangfang Li, Lili Cui, Wenyi Kang
  The hepatoprotective effects of kiwifruit seed oil (KSO) was evaluated with acute liver injury (ALI) established by carbon tetrachloride (CCl4) in vivo. Network pharmacology was used to predict active compounds...
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Limosilactobacillus fermentum HNU312 alleviates lipid accumulation and
inflammation induced by high-fat diet: improves lipid metabolism pathways
and short-chain fatty acids in gut microbiome
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02390K, PaperJiahe Li, Zeng Zhang, Yuan Xu, Wanggao Li, Shuaiming Jiang, Jiachao Zhang, Hui Xue
  High-fat diet can cause health problems, such as hyperlipidemia, obesity, cardiovascular disease, and metabolic disorders. Dietary supplementation with beneficial microbes might reduce the detrimental effects of a high-fat diet by...
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In vitro gastrointestinal digestion and fecal fermentation of Pleurotus
eryngii protein extracted using different methods-insights for the
utilization of edible mushroom-based proteins as novel nutrient and
functional component
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02604G, PaperXinyi Li, Qi Tao, Qiuhui Hu, Ning Ma, Gaoxing Ma
  Pleurotus eryngii protein is considered high quality protein based on its rich and comprehensive essential amino acids, and has also been proved displaying multiple significant functional characterizations of which vary...
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Protective effect of 1,3-dioleoyl-2-palmitoylglycerol against DSS-induced
colitis via modulating gut microbiota and maintaining intestinal
epithelial barrier integrity
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02344G, PaperWusun Li, Xiaoyan Tang, Hui Liu, Ke Liu, Zhiqing Tian, Yujie Zhao
  A schematic diagram illustrates how OPO protects against DSS-induced colitis by modulating gut microbiota, enhancing intestinal epithelial barrier integrity, and subsequently downregulating the TLR4-MyD88-NF-κB signaling pathway.
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Integrated transcriptomics and metabolomics explore the effects of infant
formula on the growth and development of small intestinal organoids
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01723D, PaperXianli Wang, Yuxin Jing, Chengdong Zheng, Chenxuan Huang, Haiyang Yao, Zimo Guo, Yilun Wu, Zening Wang, 正阳吴, Ruihong Ge, Wei Cheng, Yuanyuan Yan, Shilong Jiang, Jianguo Sun, Jingquan Li, Qing gang Xie, Xiaoguang Li, Hui Wang
  Infant formulas are designed to provide sufficient energy and the necessary nutrients to support the growth and development of newborns. Currently, research on the functions of formula milk powder focuses...
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The formation of sulfur metabolites during in vitro gastrointestinal
digestion of fish, white and red meat is affected by the addition of
fructo-oligosaccharides
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00928B, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Núria Elias Masiques, Els Vossen, Jo De Vrieze, S. De Smet, Thomas Van Hecke
  The formation of sulfur metabolites during large intestinal fermentation of red meat may affect intestinal health. In this study, four muscle sources with varying heme-Fe content (beef, pork, chicken and...
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Urinary alkylresorcinol metabolites, biomarkers of whole grain wheat and
rye intake, are beneficially associated with liver fat and other fat
measures
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01248H, PaperZisuo Sun, Yaling Shao, Xiaoyu Zhang, Zhihao Zhou, Shu Ye, Mengfei Liu, Yaning Lv, Shaoyu Xie, Hongjun Cao, Zhuang Zhang, Wanshui Yang
  3-(3,5-Dihydroxyphenyl)-1-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA) are biomarkers of whole grain wheat and rye intake.
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Uric acid reducing effect and its mechanism of Prunus salicina Lindl. cv.
"furong" polyphenols on the hyperuricemia mice induced by hypoxanthine and
potassium oxonate
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02391A, PaperWU Li, Kexin Yi, Zheng Xiao, Qing Xia, Yuping Cao, Shouhui Chen, Yibin Li
  The incidence of hyperuricemia (HUA) is gradually showing a trend towards younger individuals, and it can significantly harm the overall health status of the body. The uric acid lowering effect...
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Nutritional, antioxidant and biological activity characterization of
orange peel flour to produce nutraceutical gluten-free muffins
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01395F, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Giusy Rita Caponio, Alessandro Annunziato, Mirco Vacca, Graziana Difonzo, Giuseppe Celano, Fabio Minervini, Marianna Ranieri, Giovanna Valenti, Grazia Tamma, Maria De Angelis
  Celiac disease – a prevalent food intolerance – requires strict adherence to a lifelong gluten-free (GF) diet as the only effective treatment.
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Bifidobacterium lactis IDCC 4301 (B. lactis Fit™) supplementation
effects on body fat, serum triglyceride, and adipokine ratio in obese
women: a randomized clinical trial
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO00535J, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Miji Lee, Min Kyung Bok, Kumhee Son, Minjee Lee, HyunMin Park, Jungwoo Yang, Hyunjung Lim
  When obese women consumed Bifidobacterium lactis IDCC 4301 (B. lactis Fit™) at a concentration of >5 × 109 CFU day−1 for 12 weeks, decrease in body fat was greater in the probiotics group than in the placebo group.
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Dietary supplementation with capsaicinoids alleviates obesity in mice fed
a high-fat-high-fructose diet
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02102A, PaperZixing Chen, Jianhui Liu, Huafang Ding, Chi Yan, Hanyue Zhu, Shouhe Huang, Zhen-Yu Chen
  Capsaicinoids are the pungent compounds in chili peppers. The present study investigated the effect of capsaicinoids on obesity in mice induced by feeding a high-fat-high-fructose diet. Thirty-two male C57BL/6J mice...
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A Systematic Review and Meta-Analysis of Randomized Controlled Trials:
Effects of Mediterranean Diet and Low-fat Diet on Liver Enzymes and Liver
Fat Content of NAFLD
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01461H, Review Articleyalan xiong, Xinyu Shi, Xinying Xiong, Shengyu Li, Hanhua Zhao, Hualing Song, Jianying Wang, Lei Zhang, Shengfu You, Guang Ji, Baocheng Liu, Na Wu
  Background: Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of several chronic diseases, imposing a significant global economic burden. The Mediterranean diet (MD) and low-fat diet (LFD)...
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Four novel anti-adhesive activity peptides against Helicobacter pylori
derived from rice bran protein: release, identification and anti-adhesive
mechanisms elucidation
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01734J, PaperGuanlong Li, Zhengfei Miao, Xiaolan Liu, QuanXin Wang, Xiqun Zheng
  Four novel anti-adhesive activity peptides against Helicobacter pylori derived from rice bran protein were found.
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Selenoprotein H mediates low selenium-related cognitive decline through
impaired oligodendrocyte myelination with disrupted hippocampal lipid
metabolism in female mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00888J, PaperQingqing Lv, Aolin Yang, Ziyu Han, Ruirui Yu, Junying Zhu, Zhan Shi, Chenggang Yang, Shimiao Dai, Mengru Hao, Yuqing Chen, Ji-Chang Zhou
  Low selenium levels are closely associated with reduced cognitive performance and lipid dysregulation, yet the mechanism of action remains unclear. The physiological function of selenium is primarily mediated by selenoproteins....
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Association between pre- and post-diagnosis healthy eating index 2020 and
ovarian cancer survival: evidence from a prospective cohort study
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02417F, PaperJia-Cheng Liu, Fang-Hua Liu, De-Yu Zhang, Xiao-Ying Wang, Lang Wu, Yi-Zi Li, He-Li Xu, Yi-Fan Wei, Dong-Hui Huang, Xiao-Ying Li, Qian Xiao, Meng-Meng Xie, Pei-Chen Liu, Song Gao, Chuan Liu, Ning Liu, Ting-Ting Gong, Qi-Jun Wu
  Adherence to the healthy eating index-2020 before and after diagnosis is associated with better overall survival in patients with ovarian cancer.
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Regulatory effect of β-glucan secreted by Rhizobium pusense on
triglyceride metabolism and their relationships with the modulation of
intestinal microbiota in mice fed with high-fat diet
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01123F, PaperBin Zhang, Wei Zhao, Dong Song, Xiaomei Lyu
  The present study investigated the regulatory effects of β-glucan secreted by Rhizobium pusense (RPG) on triglyceride metabolism and gut microbiota in mice. Results showed that supplementation with RPG markedly reduced...
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Capsaicin alleviates acute alcohol-induced pyroptosis by activating
ESCRT-III-dependent cell membrane repair in hepatocytes
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO00806E, PaperMeitong Liu, Jiakang Guo, Jing Lu, Yuelin Chen, Xuming Deng, Shengzhuo Zhang, Shuang Guan
  CAP alleviated acute alcohol-induced pyroptosis via TRPV1-Ca2+ influx-ESCRT-III-dependent membrane repair machinery, which relieved AALI.
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Effects of Lactiplantibacillus plantarum CCFM1214 and Ligilactobacillus
salivarius CCFM1215 on halitosis: a double-blind, randomized controlled
trial
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02280G, PaperLijiang Ding, Yueyan Wang, Zhentao Jiang, Xin Tang, Bingyong Mao, Jianxin Zhao, Wei Chen, Qiuxiang Zhang, Shumao Cui
  The purpose of this study was to evaluate the effects of known probiotic species Lactiplantibacillus plantarum CCFM1214 and Ligilactobacillus salivarius CCFM1215 on halitosis, the oral status, and the oral microbiome.
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The effect of iron absorption in ferrous gluconate form from enriched rice
flour using in-vitro digestion and Caco-2 cell model
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01441C, PaperJing Lin, Caiyu Liu, Ru Bai, Chi Zhang, Jinzhu Pang, Zhengdong Liu, Xingwang Ye, Shuangshuang Chen, Xinqi Liu, He Li, Sumei Hu
  Iron deficiency can cause serious diseases in infants and young children such as indigestion, anemia, and nervous system dysplasia. Consumption of high-iron rice flour can prevent iron deficiency. The objective...
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Quercetin ameliorates neuroinflammatory and neurodegenerative biomarkers
in brain and improves neurobehavioral parameters in repeated intranasal
amyloid-beta exposed model of Alzheimer’s disease
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02602K, PaperVaibhav Uttamrao Lasure, Avtar Singh Gautam, Rakesh Kumar Singh
  Objectives: The aim of the present study was to study the potential therapeutic effects of quercetin in protection against repeated intranasal exposure of amyloid-beta-induced mice model. Methods: Mice received intranasal...
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Ovomucin and its hydrolysates differentially influenced colitis severity
in Citrobacter rodentium-infected mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01813C, PaperXiaoyu Bao, Tingting Ju, Stephanie Tollenaar, Consolato Sergi, B. P. Willing, J. P. Wu
  Egg white protein ovomucin and its hydrolysates were previously reported to exert anti-inflammatory and anti-adhesive activities. However, their potential to regulate pathogen colonization and disease severity has not been fully...
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Metabolic profiling of (poly)phenolic compounds in mouse urine following
consumption of hull-less and purple-grain barley
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01275E, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maria Engracia Cortijo-Alfonso, Silvia Yuste, Ivan Friero, Mariona Martínez-Subirà, Marian Moralejo, Carme Piñol, Laura Rubió-Piqué, Alba Macià
  The present study attempted for the first time to investigate the metabolic fate of (poly)phenolic compounds provided by a hull-less and purple grain barley genotype biofortified in anthocyanins. Balb/c mice...
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Miao sour soup alleviates DSS-induced colitis in mice: modulation of gut
microbiota and intestinal barrier function
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01794C, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lincao Li, Haiyan Sun, Lunbo Tan, Hui Guo, Lisi He, Jieyu Chen, Shuting Chen, Dong Liu, Mingjun Zhu, Zijun OuYang
  Miao sour soup (MSS), a daily fermented food in Guizhou, China, is rich in microorganisms with various beneficial activities, including anti-inflammatory and antioxidant activities.
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Lacticaseibacillus rhamnosus GG alleviate sleep deprivation
induced-intestinal barrier dysfunction and neuroinflammation in mice
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00244J, PaperXiaoqi Pang, Bingqian Zhou, Jingyi Wu, Qi Mo, Lijiao Yang, Tiaotiao Liu, Ge Jin, Lan Zhang, Xiang Liu, Xin Xu, Bangmao Wang, Hailong Cao
  Consuming probiotic products is a solution that people are willing to choose to augment health. As one of the global health hazards, sleep deprivation (SD) can cause both physical and...
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Diet enriched with high-phenolic cocoa potentiates hippocampal
brain-derived neurotrophic factor and neurogenesis in healthy adult mice
with subtle effects on memory
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01201A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sonia Melgar-Locatelli, M. Carmen Mañas-Padilla, Adriana Castro-Zavala, Patricia Rivera, Maria del Carmen Razola-Diaz, Francisco Monje Quiroga, Celia Rodríguez-Pérez, Estela Castilla-Ortega
  Cocoa is widely known for its health benefits, but its neurocognitive impact remains underexplored. This preclinical study aimed to investigate the effects of cocoa and cocoa polyphenols on hippocampal neuroplasticity,...
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A protective mechanism of heat inactivation to enhance Levilactobacillus
brevis PDD-2 against alcohol-induced chronic liver disease based on
proteomic analysis
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01051E, PaperMingzhen Liu, Xiaoxiao Jiang, Xiaoqun Zeng, Yuxing Guo, Tao Zhang, Xiankang Fan, Jue Xu, Zhen Wu, Daodong Pan
  L. brevis PDD-2 and its postbiotics (heat-inactivated L. brevis PDD-2) alleviate chronic ALD via the gut-liver axis. The postbiotics are equal to or even superior to live bacteria in their ability to alleviate alcoholic liver injury.
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The effects of caffeine on pancreatic diseases: the known and possible
mechanisms
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02994A, Review ArticleLetian Pan, Qixiang Mei, Qiuyun Gu, Mingyu Duan, Chenyuan Yan, Yusen Hu, Yue Zeng, Junjie Fan
  Caffeine, a controversial substance, was once known to be addictive and harmful. In recent years, new effects of caffeine on the human body have been confirmed. Recent research over the...
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Tea, coffee, and caffeine intake and risk of dementia and Alzheimer's
Disease: a systematic review and meta-analysis of cohort studies
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01750A, PaperFengjuan Li, Xiaoning Liu, Bin Jiang, Xinying Li, Yanqi Wang, Xiaojuan Chen, Yuhao Su, Xiaojie Wang, Jun Luo, Lifang Chen, Jiangtao Li, Qian Lv , Jian Xiao, Jun Wu, Jianping Ma, Pei Qin
  Background Limited and conflicting evidence exists on the associations between tea, coffee, and caffeine intake and risk of dementia and Alzheimer's Disease (AD). This meta-analysis aimed to elucidate these associations...
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Mulberry polyphenols restored both small and large intestinal microflora
in db/db mice, potentially alleviating type 2 diabetes
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01291G, PaperFuhua Li, Jian Ming
  Polyphenols in mulberry fruit have potential antidiabetic effects by targeting gut microbiota. This study investigated how mulberry polyphenols (MP) influence the microbiota of the small and large intestines and their...
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An examination of the impact of unmelted, melted, and deconstructed cheese
on lipid metabolism: a 6-week randomised trial
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO02708F, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Aileen O'Connor, Martina Rooney, Simone Dunne, Nupur Bhargava, Caroline Matthews, Shuhua Yang, Sitong Zhou, Adam Cogan, Jeremiah J. Sheehan, André Brodkorb, Nessa Noronha, Michael O'Sullivan, Dolores O'Riordan, Emma L. Feeney, Eileen R. Gibney
  An RCT investigating the effect of deconstructing the cheese matrix by melting on cardio-metabolic health.
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Associations of dietary patterns with risk of gastrointestinal disorders:
a prospective cohort study
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01668H, PaperWeiyi Chen, Yingying Zhao, Haojie Lu, Jing Yi, Jia Li, Xuemei Song, Jia Zhang, Shuaishuai Yang, Jingjing Ni, Zhen Wang, Yuting Shi, Yuxin Ni, Zhihao Zhang, Sijia Zhu, Shaofa Nie, Li Liu
  Gastrointestinal (GI) disorders are highly prevalent and severely diminish life quality. It is yet unknown which dietary pattern is optimal for the prevention of GI disorders. Among 141,450 participants from...
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Sex-specific effects of intermittent fasting on hippocampal neurogenesis
via the gut-brain axis
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00318G, PaperYimin Luo, Hui Wang, Zhaomin Chen, Yuqing Deng, Yuran Zhang, Wenjie Hu
  Intermittent fasting (IF) is a widely used dietary strategy that has shown several advantageous impacts on general health and aging. IF has recently been linked to the control of neurogenesis,...
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N-Glycan profile of the cell membrane as a probe for
lipopolysaccharide-induced microglial neuroinflammation uncovers the
effects of common fatty acid supplementation
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  Abstract: Food Funct., 2024, Advance Article
  
  DOI : 10.1039/D4FO01598C, PaperSheryl Joyce B. Grijaldo-Alvarez, Michael Russelle S. Alvarez, Ryan Lee Schindler, Armin Oloumi, Noah Hernandez, Tristan Seales, Jorge Gil C. Angeles, Ruel C. Nacario, Gladys C. Completo, Angela M. Zivkovic, J. Bruce German, Carlito B. Lebrilla
  Aberrant glycosylation induced by LPS in the microglial glycocalyx can be restored by dietary and gut microbe-derived fatty acids highlighting their potential to relieve neuroinflammation.
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A Review of the Biological Activities of Lactoferrin: Mechanisms and
Potential Applications
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO02083A, Review ArticleRuiyao Hong, Aijun Xie, Chengxi Jiang, Yangze Guo, Yumeng Zhang, Jiali Chen, Xinyu Shen, Mohan Li, Xiqing Yue
  Lactoferrin, a multifunctional iron-binding protein found in milk and other body fluids, possesses numerous biological activities. The functional activity of lactoferrin lies not only in its iron-binding capacity, but also...
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Hexane Insoluble Fraction from Purple Rice Extract Improves
Steatohepatitis and Fibrosis via Inhibition of NF-κB and JNK Signaling
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00292J, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.A. Naiki-Ito, Ranchana Yeewa, Kuang Xiaochen, Weerakit Taychaworaditsakul, Taku Naiki, Hiroyuki Kato, Yuko Nagayasu, TEERA CHEWONARIN, Satoru Takahashi
  Nonalcoholic fatty liver disease (NAFLD) is fatty liver mainly related to metabolic syndrome. NAFLD with inflammation and hepatocellular damage is defined as nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis...
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Association between dietary vitamin C intake/blood level and risk of
digestive system cancer: a systematic review and meta-analysis of
prospective studies
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO00350K, Review ArticleJiamin Zhong, Peiwei Li, Fang Zheng, Yating Li, Wei Lu, Hanwen Chen, Jianting Cai, Dajing Xia, Yihua Wu
  Experimental studies have shown that vitamin C has anti-cancer effects, but previous meta-analyses have indicated that the role of vitamin C in digestive system cancers (DSCs) is controversial. In this...
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In vivo absorption and excretion in rats and in vitro digestion and
fermentation by human intestinal microbiota of
2-O--D-glucopyranosyl-L-ascorbic acid from the fruits of Lycium
barbarum L.
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  Abstract: Food Funct., 2024, Accepted Manuscript
  
  DOI : 10.1039/D4FO01894J, PaperWei Dong, Yujia Peng, Weiqi Xu, Wangting Zhou, Yamei Yan, Jia Mi, Lu Lu, Youlong Cao, Xiaoxiong Zeng
  2-O--D-Glucopyranosyl-L-ascorbic acid (AA-2G) from Lycium barbarum fruits has diverse bioactivities, yet its absorption and digestion are poorly understood. Therefore, the in vivo absorption of AA-2G in rats was investigated in...
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