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  Subjects -> NUTRITION AND DIETETICS (Total: 201 journals)
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Annals of Nutrition and Metabolism
Journal Prestige (SJR): 1.317
Citation Impact (citeScore): 3
Number of Followers: 52  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 0250-6807 - ISSN (Online) 1421-9697
Published by Karger Homepage  [122 journals]
  • Society News

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      Abstract:
      Ann Nutr Metab 2022;78:246–246
      PubDate: Tue, 09 Aug 2022 06:23:09 +020
       
  • Society News

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      Abstract:
      Ann Nutr Metab 2022;78:244–245
      PubDate: Tue, 09 Aug 2022 06:23:00 +020
       
  • Risk scores for metabolic dysfunction-associated fatty liver disease in
           pediatric obesity

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      Abstract: Introduction: Early non-invasive detection of incipient liver damage is crucial to prevent long-term adverse health outcomes. A variety of scores to assess liver status have been proposed, mostly for adult populations. Validation of non-invasive hepatic scores to identify children at risk of metabolic dysfunction-associated fatty liver disease (MAFLD) is a gap in research, particularly in youth with severe obesity considering pubertal stage and sex. Methods: In a well-characterized pediatric population aged 9 to 19 years (n=115) 19 published liver scores were analyzed. AUROC for determination of MAFLD as assessed by magnetic resonance imaging was calculated. Results: The pediatric indices PNFI, B-AST and M-APRI and several scores developed in adults significantly differed in children with MAFLD compared to children without, while some established indices did not. Only NAFLD-LFS and the model by Cao et al. showed acceptable predictive accuracy (AUROC> 0.8) independently of pubertal stage and sex. When stratifying for pubertal stage and sex, the GSG-Index was superior in pubertal girls, and NAFLD-LFS performed best in pubertal boys. Conclusion: NAFLD-LFS and the model by Cao et al. were well suited to predict MAFLD in youth with severe obesity. In pubertal children, GSG-Index and NAFLD-LFS performed best in girls and boys, respectively.

      PubDate: Fri, 05 Aug 2022 10:29:04 +020
       
  • Effect of central venous nutrition infusion, intravenous fat emulsion, and
           therapeutic agents on the particle size of fat emulsion for simultaneous
           administration of three drugs

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      Abstract: Background: In Japan, therapeutic agents are often administered through the side tube of a central venous line or mixed with a total parenteral nutrition (TPN) infusion. This is expected to result in the mixture of three drugs in the infusion line: the infusion product for TPN, the fat emulsion, and the therapeutic agent. Therefore, we investigated whether various therapeutic agents affect the particle size of the fat emulsion.Methods: In model of administration A, the TPN infusion formulation was administered through the main tube and the fat emulsion and therapeutic agents were simultaneously administered through the side tube; 21 therapeutic agents were used. In model of administration B, the TPN infusion formulation mixed with therapeutic agents was administered through the main tube and the fat emulsion was simultaneously administered through the side tube; 20 therapeutic agents were used. The number of fine particles for each particle size range in the mixed solution was measured over time using a light-shielding automatic fine particle measuring device.Results: In model A, the number of fine particles in the fat emulsion changed rapidly for five therapeutic agents and slowly for two therapeutic agents. In model B, this change occurred drastically for five therapeutic agents and slowly for one therapeutic agent.Conclusions: Some therapeutic agents may contribute to fat particle aggregation. Therefore, these therapeutic agents should not be concurrently administered with fat emulsions.

      PubDate: Fri, 05 Aug 2022 09:18:19 +020
       
  • Neck circumference predicts the occurrence and remission of metabolic
           associated fatty liver disease: A longitudinal study of community-dwelling
           population

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      Abstract: AbstractAim: Neck circumference (NC), a proxy for upper-body subcutaneous fat, is closely related to metabolic dysfunction, independent of other obesity indices. The purpose of this study was to explore the relationship between NC and the incidence and remission of metabolic associated fatty liver disease (MAFLD), a novel concept proposed by an international consensus panel in 2020 through a community-based longitudinal cohort.Methods: This study included 1549 community participants and was conducted from 2013 to 2016. MAFLD was diagnosed using the International Expert Consensus (2020) criteria. All participants underwent NC measurement and biochemical measurements. Elevated NC was defined as NC ≥38.5 cm in men and NC ≥34.5 cm in women.Results: A total of 1549 subjects (638 men and 911 women), with an average age of 59.6 ± 7.3 years, were included. During a mean follow-up of 2.1 years, MAFLD occurred in 146 of the 870 participants without baseline MAFLD and was resolved in 225 of the 679 participants with baseline MAFLD. After adjusting for confounding factors such as age, sex, body mass index, waist circumference, fasting plasma glucose and liver enzyme levels, multivariable logistic regression showed that higher NC at baseline was positively correlated with MAFLD occurrence (OR 1.96, 95% confidence interval: 1.21–3.31; P=0.003) and negatively correlated with MAFLD remission (OR 0.57, 95% confidence interval: 0.40–0.80; P
      PubDate: Wed, 20 Jul 2022 09:05:40 +020
       
  • Cinnamon Infusion Reduces Satiety and Increases Energy Intake: A
           Randomized Crossover Trial

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      Abstract: Background/Aims: This study aimed to evaluate the effects of the intake of a single dose of cinnamon infusion on energy metabolism, appetite responses and food intake in healthy individuals. Methods: This was an open randomized crossover clinical trial, with a minimum washout of seven days, which was conducted in which two standardized breakfasts were served randomly: one with cinnamon infusion (2g, Cinnamomum sp.) And one with water (control). The study included 21 healthy volunteers. Energy expenditure (EE), diet-induced thermogenesis (DIT), respiratory quotient (RQ), substrate oxidation and appetite responses were evaluated, as well as prospective food intake. Results: Ingestion of cinnamon infusion did not alter EE, DIT, RQ or substrate oxidation. The incremental area under the curve for hunger, satiety and desire to eat did not differ between the treatment with cinnamon infusion and water, however, there was a reduction in the feeling of satiety (p=0.021) compared to the control treatment. The energy consumption of the first meal after treatment was higher (p=0.05) in the treatment with cinnamon infusion than in the control treatment. Regarding macronutrients or food intake throughout the day, there was no difference between treatments. Conclusions: Although it did not affect energy metabolism, consuming a single dose of cinnamon infusion promoted less feeling of satiety and increased energy intake in the first meal after treatment. The study protocol was registered at the Brazilian Clinical Trials Registry Platform (RBR-5ftg3z).

      PubDate: Wed, 13 Jul 2022 14:22:04 +020
       
  • Association of nutritional support with survival-time in hospitalized
           older patients with dysphagia: a retrospective study

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      Abstract: Dysphagia results from age-related changes in swallowing physiology and contributes to various health status changes, including higher risks for malnutrition, pneumonia, and mortality [1, 2]. It also occurs in age-related diseases, including stroke [3] and cancer [4], and progressive neurological diseases, such as dementia [5] and Parkinson’s disease [6]. These associations, and global aging, have increased the importance of dysphagia management.Artificial nutrition can support patients with dysphagia caused by various clinical conditions. Percutaneous endoscopic gastrostomy (PEG) is an artificial nutrition method that secures an enteral nutrition (EN) route in dysphagia patients [7]. PEG tubes have been widely used in Japan as a convenient and effective EN route since approximately 1990; however, the use of PEG feeding in dementia patients is controversial [8-10]. Total parenteral nutrition (TPN) is an alternative nutritional management method [11] and has been the most frequently used nutritional support method in Japan since 2010. A comparison of long-term outcomes associated with PEG feeding and TPN in older patients found that older patients, and those with poorer nutritional status and severe dementia, were more likely to receive TPN, whereas patients with cerebrovascular disease were more likely to receive PEG [12]. A 2012 Japan Geriatric Society position statement on end-of-life care for older adults suggested that patients’ families or caregivers should decide whether feeding tubes should be withheld or withdrawn [13].Although advanced directives are now widely used, the decision of whether to institute enteral tube feeding is an important issue for older patients and their families. However, global clinical evidence for the effect of artificial nutritional support on survival-time, and for differences between administration routes, is lacking. The rate of aging in Japan is more rapid than in any other country, and more research is needed on clinical decision making for the older population. The study aim was to clarify the effects of artificial nutritional support route on survival-time of older terminal patients with dysphagia.

      PubDate: Wed, 13 Jul 2022 10:07:23 +020
       
  • Prelims

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      Abstract:
      Ann Nutr Metab 2022;78(suppl 2):1–4
      PubDate: Tue, 12 Jul 2022 07:53:42 +020
       
  • Reversal of diabesity: Normalization of insulin release curve in
           association with reversal of non-alcoholic fatty liver disease

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      Abstract: Objective: Type 2 diabetes with obesity is regarded as an incurable, progressive disease with many complications. The hypothesis was tested that HbA1c and the insulin release curve can be restored by traceable systematic methods.Methods: 122 people with diabesity were investigated before and after three and six months of traceable systematic management methods. Basal BMI, fatty liver, HbA1c and insulin release curve were measured. Results: After three months of traceable systematic management, BMI decreased from 30.76 ± 0.48 to 21.86 ± 0.09 kg/m2 (p
      PubDate: Wed, 29 Jun 2022 11:05:33 +020
       
  • Focus

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      Abstract:
      Ann Nutr Metab 2022;78(suppl 2):39
      PubDate: Wed, 29 Jun 2022 10:41:24 +020
       
 
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