First page: nzac146 Abstract: ABSTRACTBackgroundPsychosocial and physiologic stressors, such as depression and obesity, during pregnancy can have negative consequences, such as increased systemic inflammation, contributing to chronic disease for both mothers and their unborn children. These conditions disproportionately affect racial/ethnic minorities. The effects of recommended dietary patterns in mitigating the effects of these stressors remain understudied.ObjectivesWe aimed to evaluate the relations between maternal Mediterranean diet adherence (MDA) and maternal and offspring outcomes during the first decade of life in African Americans, Hispanics, and Whites.MethodsThis study included 929 mother–child dyads from the NEST (Newborn Epigenetics STudy), a prospective cohort study. FFQs were used to estimate MDA in pregnant women. Weight and height were measured in children between birth and age 8 y. Multivariable linear regression models were used to examine associations between maternal MDA, inflammatory cytokines, and pregnancy and postnatal outcomes.ResultsMore than 55% of White women reported high MDA during the periconceptional period compared with 22% of Hispanic and 18% of African American women (P < 0.05). Higher MDA was associated with lower likelihood of depressive mood (β = −0.45; 95% CI: −0.90, −0.18; P = 0.02) and prepregnancy obesity (β = −0.29; 95% CI: −0.57, −0.0002; P = 0.05). Higher MDA was also associated with lower body size at birth, which was maintained to ages 3–5 and 6–8 y—this association was most apparent in White children (3–5 y: β = −2.9, P = 0.02; 6–8 y: β = −3.99, P = 0.01).ConclusionsIf replicated in larger studies, our data suggest that MDA provides a potent avenue by which effects of prenatal stressors on maternal and fetal outcomes can be mitigated to reduce ethnic disparities in childhood obesity. PubDate: Tue, 15 Nov 2022 00:00:00 GMT DOI: 10.1093/cdn/nzac146 Issue No:Vol. 6, No. 11 (2022)
First page: nzac149 Abstract: This is a correction to: Yu Hasegawa, Ruisong Pei, Ruma Raghuvanshi, Federico Rey, Zhenhua Liu, Bradley Bolling, Yogurt Supplementation Attenuated Insulin Resistance in Obese Mice by Reducing Systemic Markers of Metabolic Endotoxemia and Inflammation, Current Developments in Nutrition, Volume 6, Issue Supplement_1, June 2022, Page 980, https://doi.org/10.1093/cdn/nzac068.009. PubDate: Tue, 15 Nov 2022 00:00:00 GMT DOI: 10.1093/cdn/nzac149 Issue No:Vol. 6, No. 11 (2022)
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