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IJS Global Health
Number of Followers: 0  Open Access journalISSN (Print) 2576-3342 - ISSN (Online) 2576-3342 Published by LWW Wolters Kluwer  [330 journals]
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- Lesson learnt from the Ebola outbreak in Uganda
Authors: Zaman; Kamran; Mohanty, Aroop; Sah, Ranjit
Abstract:
No abstract available
PubDate: Mon, 29 Jul 2024 00:00:00 GMT-
- Outbreak of an emerging zoonoses Nipah virus: an update
Authors: Sah; Ranjit; Paul, Diptanu; Mohanty, Aroop; Padhi, Bijaya K.
Abstract: No abstract available
PubDate: Fri, 26 Jul 2024 00:00:00 GMT-
- Sicca syndrome post-COVID-19 infection: a case report
Authors: Dumirieh; Sumaya; Al lahham, Leen; Tarcha, Raghad; Hoha, Ghofran; Hamsho, Suaad; Kudsi, Maysoun
Abstract: Introduction and importance: The COVID-19 pandemic has led to a post-acute syndrome that can persist for a prolonged period.Case presentation: The authors’ case reported a 31-years-old male presented with the sensation of sand in his eyes and a dry mouth for 3 months after infection with COVID-19 confirmed by nasopharyngeal swab 3 months ago. Laboratory tests including immunological profile were normal. Schirmer’s test was positive. He was treated with artificial tears with corticosteroid drops and water drinking. Within 15 days he noticed an improvement in his sicca symptoms.Clinical discussion: The post-acute COVID-19 syndrome can persist for a longer duration than expected, even after the acute onset of the disease. Some patients may experience ocular and oral symptoms such as dry mouth, dysgeusia, and dry eye diseases. The pathophysiology of these symptoms may be related to viral pathophysiologic changes, immunologic aberrations, and inflammatory reactions that destroy the tissue of salivary glands. Additionally, there is evidence of elevated autoantibodies in post-COVID-19 patients. Future studies are needed to understand the sequela of this infection.Conclusion: What makes this case special is the combination of dry eyes and dry mouth with a negative immunological profile in a young patient who had COVID without severe symptoms.
PubDate: Thu, 18 Jul 2024 00:00:00 GMT-
- A comparative study of ultrasonography (USG) and computed tomography for
detecting ureteric calculi in patients with acute flank pain, and analysis
of factors influencing ultrasound detection rates
Authors: Khatiwada; Bishnu; Mahat, Asim; Yadav, Gopal Kumar; Duwadi, Bikash; Mishra, Upama; Bhusal, Amrit; Yadav, Priti; Khadka, Hensan
Abstract:
Introduction: Urolithiasis, a frequent urologic issue, often relies on computed tomography (CT) scans, the preferred imaging technique. However, in low-income countries like Nepal, access to CT scans is limited. The authors’ study focused on comparing ultrasound (US) and CT for assessing ureteric calculi in patients with acute flank pain and examined factors influencing US detection rates in these patients.Methods: The authors conducted a cross-sectional study using purposive sampling, involving 87 participants who presented with acute flank pain at a tertiary hospital in Nepal. Ethical clearance was obtained from the institutional review board.Results: Among the 87 patients presenting with acute flank pain, the majority were male (51, 58.62%). Of the 78 cases with CT-detected ureteric calculi, the most common locations were distal ureter (23/78, 29.49%), followed by proximal ureter (21/78, 26.92%), and pelvic-ureteric junction (PUJ) (20/78, 25.64%). Ultrasound demonstrated varying sensitivities for detecting ureteric calculi: 95.00% for PUJ, 100.00% for vesicoureteric junction (VUJ), 66.67% for proximal ureter, and 56.52% for distal ureter calculi. The highest sensitivity was observed for calculi greater than 15 mm (100%), followed by 10.1–15 mm (77.7%). Overall, ultrasound exhibited a sensitivity of 76.92%, a specificity of 100%, and an accuracy rate of 79.31% in detecting calculi. Notably, patients with hematuria had significantly higher odds of ultrasound-detected ureteric calculi (odds ratio: 36.68, 4.54–296.26, P
PubDate: Fri, 12 Jul 2024 00:00:00 GMT-
- Undiagnosed Behçet’s disease presenting as Fournier’s gangrene in
undiagnosed Behçet’s disease: a case report of a young adult male
Authors: Hodaifa; Yara; Tarcha, Raghad; Alghawe, Fatima; Btrush, Sana; Batha, Wafaa; Kudsi, Maysoun
Abstract:
Introduction and importance: Behçet’s disease is a rare systemic condition, with the mean age of patients being ~30 years. It affects men more than women. Behçet’s disease should be considered in any patient with a systemic inflammatory disease characterized by recurrent orogenital ulcers and uveitis. Fournier’s gangrene is a rare life-threatening bacterial genital infection that acquires at any age with male predominance.Case presentation: A healthy 32-year-old male presented with fatigue, fever, oral ulcers, and discrete scrotal ulcers. He had Fournier’s gangrene and a new diagnosis of Behçet’s disease. He was treated with intravenous antibiotics with surgical debridement. Before discharge, the patient was commenced on 1 mg/day of colchicine. During the follow-up visits, we noted small ulcerations without necrosis on the scrotum, which we started with oral prednisolone and oral methotrexate. He remains under their care 6 months later.Clinical discussion: The patient had recurrent oral ulcerations followed by genital aphthous ulceration and acneiform eruptions that met Behçet’s diagnosing criteria. Fournier’s gangrene on the scrotum was diagnosed due to the physical examination, radiological findings, and histological findings. A PubMed search reveals one similar case report. This patient’s only risk factor for Bechet’s was his ethnicity and male gender for Fournier’s gangrene.Conclusion: The young adult patient presented unusually, with a diagnosis of Fournier’s gangrene superimposed on undiagnosed Behçet’s disease. An understanding of the epidemiology and risk factors can help in the diagnosis of these rare pathologies.
PubDate: Wed, 10 Jul 2024 00:00:00 GMT-
- Statins in breast cancer treatment and management: a mini-review of
potential benefits and clinical implications
Authors: Aftab; Aleena; Hussain, Tooba; Hussain, Rameez; Shah, Hussain Haider; Habiba, Ume; Haque, Md Ariful
Abstract: No abstract available
PubDate: Thu, 04 Jul 2024 00:00:00 GMT-
- Coexistence of Hashimoto’s thyroiditis, rheumatoid arthritis,
Sjogren’s syndrome, and ulcerative colitis
Authors: Kudsi; Maysoun; Khalayli, Naram; Haj Ali, Diaa; Al-Darwish, Lama
Abstract:
Introduction and importance: The coexistence of Hashimoto’s thyroiditis and ulcerative colitis has been previously mentioned, as these diseases are autoimmune diseases. Limited data about the coexistence of rheumatoid arthritis in patients with Hashimoto’s thyroiditis have been published till now. Meanwhile, the coexistence of Sjogren’s syndrome during the course of rheumatoid arthritis is well known. The coexistence of Hashimoto’s thyroiditis, Sjogren’s syndrome, and ulcerative colitis has also been reported in rare cases.Case presentation: A 32-year-old female, with a 10-year history of Hashimoto’s thyroiditis, 4 years of rheumatoid arthritis, and 2 years of secondary Sjogren’s syndrome, presented to our Rheumatology Department, complaining of fatigue, weight loss, intermittent abdominal pain, and bloody diarrhea for the last 6 weeks. Her colonoscopy findings were compatible with a diagnosis of ulcerative colitis.Clinical discussion: Multiple autoimmune syndromes are defined as the presence of three or more autoimmune diseases in the same patient. They have an increased frequency in patients with a previous history of another autoimmune disease, and a higher correlation with females. The prevalence is rare and was documented only by two systematic reviews, with the rest being separate case reports. Autoimmune thyroid disease and Sjögren’s syndrome were the most frequent diseases encountered, followed by rheumatoid arthritis, and systemic lupus erythematosus. The presence of these autoimmune diseases together suggests that they share a common pathological and physiological genesis.Conclusion: This is the first case report, to our knowledge, that describes the coexistence of Hashimoto’s thyroiditis, rheumatoid arthritis, Sjogren’s syndrome, and ulcerative colitis within 10 years, without a positive family history or psychological stress. Therefore, further studies and long-term surveys are needed to identify other factors that can contribute to the coexistence of these rare diseases.
PubDate: Wed, 26 Jun 2024 00:00:00 GMT-
- Measurement of humanity among interns of Internal Medicine Department,
Damascus University: a cross-sectional study
Authors: Drie; Tasneem; Hodifa, Yara; Haidar, Ghina; Soud Alkousa, Hamzeh; Khalayli, Naram; Hodaifa, Amr; Hoha, Ghofran; Alghawe, Fatima; Kudsi, Maysoun
Abstract:
Background: Although humanity is important within the medical health field, the authors lack studies that address this topic.Objective: The authors aimed to assess humanity among a sample of Syrian internal medicine interns.Methods: The authors have used a validated scale based on the Medical Humanity Scale (MHS) categorized into seven human values included in 30 questions (patient-oriented care, respect, empathy, ethics, altruism, and compassion). The scale can test the differentiation between these interns with different levels of medical humanity. A 7-point Likert scale was adopted. Six hundred sixty-five participants from the Internal Medicine Department, Faculty of Medicine, Damascus University entered our study.Results: The mean score of the MHS was 147.14 (13.1) Female residents humanity scores (mean 149.14, SD 15.1) was significantly higher than male students’ scores (mean 145.48, SD 13.35; P=.007), KMO=0.843>0.7, which is near 1, and the Bartlett test of sphericity =4187.043 (df=465; P=.01). The Cronbach α was>0.683, was indicating the validity and reliability of the scale.Conclusions: The results of this study suggest that the humanity level is accepted by using a scale based on MHS among interns of the Internal Medicine Department, Damascus University.
PubDate: Wed, 19 Jun 2024 00:00:00 GMT-
- Oral health in Behçet’s disease and its association with disease
severity: a case-control study
Authors: Khalayli; Naram; Haidar, Ghina; Ataya, Jawdat; Al Darwish, Lama; Rabah, Nour; Rabah, Karam; Ataya, Jamal; Kudsi, Maysoun
Abstract:
Background: Behçet’s disease is a chronic autoimmune disorder that affects various organs, including oral aphthae, genital ulceration, cutaneous manifestation, ocular involvement, and positive pathergy test according to the International Study Group for Behçet’s Disease criteria. This study aimed to investigate the oral health condition of patients with Behçet’s disease and to assess how it correlates with the patient’s gender, clinical symptoms, and severity of the disease.Methods: A total of 92 participants, including 42 patients with Behçet’s disease and 50 healthy controls, were enrolled in this case-control study. The periodontal indices were measured and compared between the two groups. Logistic regression analysis was used to identify potential risk factors for disease severity. The P value must be (P
PubDate: Wed, 19 Jun 2024 00:00:00 GMT-
- Factors responsible for the re-emergence of Monkeypox and implications for
global health
Authors: Oduoye; Malik Olatunde; Faloye, Temidayo Odianosen; Ubechu, Samuel Chinonso; Nafula, Wechuli Polyne; Abu Taleb, Yara Khaled; Gharaibeh, Reham Sameeh; Irfan, Hamza; Ojebola, Abisola Motunrayo; Marbell, Andrew; Agbeyewo, Ganiyat Temitope; Valentina Sih, Che Mbali; Jamiu, Abdullahi Temitope; Khan Suheb, Mahammed
Abstract:
The eradication of smallpox in 1980 and the subsequent discontinuation of smallpox vaccination have resulted in a decline in immunity against orthopoxviruses. As a result, Monkeypox (Mpox) has reappeared as a significant virus with implications for public health. This article aims to determine some of the factors responsible for the re-emergence of Mpox and its implications for global health. A thorough literature search for this present article was conducted through a search of databases and journals, including the WHO and CDC websites, using keywords such as “Monkeypox”, “Re-emergence”, “Prevalence”, “Risk factors”, “Implications” and “Global Health” to find articles published from 2003 to 2023. We found that Mpox recently occurred in several countries in America, Europe, and Asia, including the United States of America (USA), Brazil, Spain, Colombia, Mexico, the United Kingdom (UK), Germany, and Pakistan, between 2022 and 2023. The rise in Mpox cases was also seen, with incidences documented in Western Europe (2599 cases, accounting for 42.76% of the total), Southern Europe (1932 cases, representing 31.79% of the total), Northern Europe (1487 cases, comprising 24.46% of the total), and Eastern Europe (59 cases, making up 0.97% of the total). Possible factors implicated in the re-emergence of MPOX include; the expansion of the human population, increased same sexual intercourse, and poor epidemiological surveillance. etc. The re-emergence of Mpox in the world is a difficult issue that requires world leaders to take a diverse approach to control the disease. World leaders and scientists must pursue natural compounds with antiviral properties. Hopefully, natural products will give alternate therapy alternatives for preventing infection transmission between humans and limiting virus proliferation in host organisms.
PubDate: Wed, 19 Jun 2024 00:00:00 GMT-
- A pattern of admission and outcome of patients admitted to the intensive
care unit of a tertiary hospital in a low resource setting: a cohort study
Authors: Bime; Aman E.; Bayissa, Badhaasaa B.
Abstract:
Background: ICU is a specialized department designed to serve critical care for severely ill patients. It needs an adequate number of highly trained and skilled human power and costly materials, which has limited its number and functionality in low resource settings. As a result, intensive care medicine or critical care services are poorly developed, or at most, still in the infancy stage. Due to the multifactorial limitations, ICU treatment outcomes were lower compared to high-income countries from the limited available literature. The objective of this study was to depict ICU treatment patterns and patient outcomes at low resources and limited setup.Methods: A retrospective cohort study was conducted on patients admitted to ICU from January 2017 to 31 December 2020, on a sample of 420 cases using a systematic sampling technique. Patient data were collected from the medical record and filled into a prevalidated checklist from admission to discharge or death. Data were analyzed using a statistical package for social sciences version 25.0.Result: A total of 419 patients’ data was qualified for analysis with ICU mortality being 40.8%. The majority of the admissions to the ICU were from the surgical department followed by trauma admissions. Some of the factors significantly associated with ICU mortality were: vasopressor use during the course of ICU follow up adjusted odd ratio (aOR)=4.3 with 95% CI: 1.83–10.03, P-value
PubDate: Mon, 10 Jun 2024 00:00:00 GMT-
