Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (686 journals)                  1 2 3 4 | Last

Showing 1 - 200 of 203 Journals sorted alphabetically
ACM Transactions on Computing for Healthcare     Hybrid Journal  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Adultspan Journal     Hybrid Journal   (Followers: 1)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 11)
Advances in Public Health     Open Access   (Followers: 33)
Adversity and Resilience Science : Journal of Research and Practice     Hybrid Journal   (Followers: 3)
African Health Sciences     Open Access   (Followers: 7)
African Journal of Health Professions Education     Open Access   (Followers: 7)
Afrimedic Journal     Open Access   (Followers: 3)
Ageing & Society     Hybrid Journal   (Followers: 40)
Aging and Health Research     Open Access   (Followers: 5)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
Akademika     Open Access  
American Journal of Family Therapy     Hybrid Journal   (Followers: 8)
American Journal of Health Economics     Full-text available via subscription   (Followers: 26)
American Journal of Health Education     Hybrid Journal   (Followers: 37)
American Journal of Health Promotion     Hybrid Journal   (Followers: 23)
American Journal of Health Sciences     Open Access   (Followers: 11)
American Journal of Preventive Medicine     Hybrid Journal   (Followers: 33)
American Journal of Public Health     Full-text available via subscription   (Followers: 226)
American Journal of Public Health Research     Open Access   (Followers: 33)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 9)
Annals of Health Law     Open Access   (Followers: 7)
Applied Biosafety     Hybrid Journal   (Followers: 2)
Applied Ergonomics     Hybrid Journal   (Followers: 18)
Archives of Suicide Research     Hybrid Journal   (Followers: 13)
Archivos de Prevención de Riesgos Laborales     Open Access  
ASA Monitor     Full-text available via subscription   (Followers: 15)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 7)
Asia Pacific Journal of Health Management     Full-text available via subscription   (Followers: 4)
Asia-Pacific Journal of Public Health     Hybrid Journal   (Followers: 12)
Asian Journal of Gambling Issues and Public Health     Open Access   (Followers: 5)
Asian Journal of Medicine and Health     Open Access   (Followers: 1)
Atención Primaria     Open Access   (Followers: 2)
Atención Primaria Práctica     Open Access   (Followers: 1)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 5)
Australian Family Physician     Full-text available via subscription   (Followers: 2)
Australian Indigenous HealthBulletin     Free   (Followers: 5)
Autism & Developmental Language Impairments     Open Access   (Followers: 18)
Bijzijn XL     Hybrid Journal  
Biomedical Safety & Standards     Full-text available via subscription   (Followers: 7)
Biosafety and Health     Open Access  
Biosalud     Open Access  
BMC Oral Health     Open Access   (Followers: 5)
BMC Pregnancy and Childbirth     Open Access   (Followers: 20)
Brazilian Journal of Medicine and Human Health     Open Access  
British Journal of Health Psychology     Hybrid Journal   (Followers: 56)
Cadernos de Educação, Saúde e Fisioterapia     Open Access  
Cadernos de Saúde     Open Access  
Cambridge Quarterly of Healthcare Ethics     Hybrid Journal   (Followers: 13)
Canadian Journal of Community Mental Health     Full-text available via subscription   (Followers: 16)
Canadian Journal of Human Sexuality     Hybrid Journal   (Followers: 1)
Canadian Journal of Public Health     Hybrid Journal   (Followers: 30)
Cannabis and Cannabinoid Research     Hybrid Journal   (Followers: 2)
Carta Comunitaria     Open Access  
Case Reports in Women's Health     Open Access   (Followers: 4)
Central Asian Journal of Global Health     Open Access   (Followers: 2)
CES Medicina     Open Access  
CES Salud Pública     Open Access  
Child and Adolescent Obesity     Open Access   (Followers: 9)
Child's Nervous System     Hybrid Journal  
Childhood Obesity and Nutrition     Open Access   (Followers: 12)
Children     Open Access  
Ciencia & Salud     Open Access  
Ciencia & Trabajo     Open Access  
Ciencia y Salud     Open Access   (Followers: 1)
Cities & Health     Hybrid Journal   (Followers: 5)
Cleaner and Responsible Consumption     Open Access  
Clinical and Experimental Health Sciences     Open Access   (Followers: 1)
ClinicoEconomics and Outcomes Research     Open Access   (Followers: 1)
Clocks & Sleep     Open Access   (Followers: 2)
CME     Hybrid Journal   (Followers: 1)
Conflict and Health     Open Access   (Followers: 8)
Contact (CTC)     Open Access   (Followers: 2)
Contraception and Reproductive Medicine     Open Access   (Followers: 2)
Cuaderno de investigaciones: semilleros andina     Open Access  
Current Opinion in Behavioral Sciences     Hybrid Journal   (Followers: 11)
Current Opinion in Environmental Science & Health     Hybrid Journal  
Das österreichische Gesundheitswesen ÖKZ     Hybrid Journal   (Followers: 2)
Day Surgery Australia     Full-text available via subscription   (Followers: 2)
Design for Health     Hybrid Journal   (Followers: 1)
Digital Health     Open Access   (Followers: 10)
Disaster Medicine and Public Health Preparedness     Hybrid Journal   (Followers: 12)
Discover Social Science and Health     Open Access   (Followers: 18)
Diversity and Equality in Health and Care     Open Access   (Followers: 10)
Diversity of Research in Health Journal     Open Access   (Followers: 1)
Dramatherapy     Hybrid Journal   (Followers: 2)
Drogues, santé et société     Open Access   (Followers: 2)
Early Childhood Research Quarterly     Hybrid Journal   (Followers: 26)
East African Journal of Public Health     Full-text available via subscription   (Followers: 3)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 24)
EcoHealth     Hybrid Journal   (Followers: 6)
Egyptian Journal of Nutrition and Health     Open Access   (Followers: 9)
Egyptian Journal of Occupational Medicine     Open Access   (Followers: 5)
electronic Journal of Health Informatics     Open Access   (Followers: 7)
ElectronicHealthcare     Full-text available via subscription   (Followers: 2)
Emerging Trends in Drugs, Addictions, and Health     Open Access   (Followers: 2)
Environmental Sciences Europe     Open Access   (Followers: 2)
Epidemics     Open Access   (Followers: 7)
EsSEX : Revista Científica     Open Access  
Ethics & Human Research     Hybrid Journal   (Followers: 4)
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 9)
Ethiopian Journal of Health Development     Open Access   (Followers: 7)
Ethiopian Journal of Health Sciences     Open Access   (Followers: 6)
Ethnicity & Health     Hybrid Journal   (Followers: 17)
EUREKA : Health Sciences     Open Access  
European Journal of Health Communication     Open Access  
European Journal of Investigation in Health, Psychology and Education     Open Access   (Followers: 5)
European Medical, Health and Pharmaceutical Journal     Open Access   (Followers: 2)
Evaluation & the Health Professions     Hybrid Journal   (Followers: 12)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exploratory Research in Clinical and Social Pharmacy     Open Access   (Followers: 4)
F&S Reports     Open Access   (Followers: 2)
Face à face     Open Access  
Family & Community Health     Hybrid Journal   (Followers: 12)
Family Relations     Partially Free   (Followers: 12)
FASEB BioAdvances     Open Access   (Followers: 3)
Fatigue : Biomedicine, Health & Behavior     Hybrid Journal   (Followers: 3)
Finnish Journal of eHealth and eWelfare : Finjehew     Open Access  
Food and Public Health     Open Access   (Followers: 11)
Food Hydrocolloids for Health     Open Access  
Food Quality and Safety     Open Access   (Followers: 2)
Frontiers in Digital Health     Open Access   (Followers: 4)
Frontiers of Health Services Management     Partially Free   (Followers: 7)
Gaceta Sanitaria     Open Access   (Followers: 2)
Ganesha Journal     Open Access  
Geospatial Health     Open Access   (Followers: 1)
Gestão e Desenvolvimento     Open Access  
Gesundheitsökonomie & Qualitätsmanagement     Hybrid Journal   (Followers: 7)
Giornale Italiano di Health Technology Assessment     Full-text available via subscription  
Global Advances in Health and Medicine     Open Access  
Global Challenges     Open Access   (Followers: 2)
Global Health : Science and Practice     Open Access   (Followers: 7)
Global Health Annual Review     Open Access   (Followers: 2)
Global Health Innovation     Open Access   (Followers: 3)
Global Health Journal     Open Access   (Followers: 2)
Global Health Promotion     Hybrid Journal   (Followers: 16)
Global Journal of Health Science     Open Access   (Followers: 6)
Global Medical & Health Communication     Open Access   (Followers: 1)
Global Mental Health     Open Access   (Followers: 13)
Global Reproductive Health     Open Access   (Followers: 1)
Global Security : Health, Science and Policy     Open Access   (Followers: 1)
Global Transitions     Open Access   (Followers: 1)
Globalization and Health     Open Access   (Followers: 7)
Hacia la Promoción de la Salud     Open Access  
Hastane Öncesi Dergisi     Open Access  
Hastings Center Report     Hybrid Journal   (Followers: 7)
HEADline     Hybrid Journal  
Health & Place     Hybrid Journal   (Followers: 23)
Health & Justice     Open Access   (Followers: 5)
Health : An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine     Hybrid Journal   (Followers: 21)
Health and Social Care Chaplaincy     Hybrid Journal   (Followers: 10)
Health and Social Work     Hybrid Journal   (Followers: 63)
Health Behavior and Policy Review     Full-text available via subscription   (Followers: 5)
Health Behavior Research     Open Access   (Followers: 2)
Health Care Analysis     Hybrid Journal   (Followers: 13)
Health Equity     Open Access   (Followers: 4)
Health Information Management Journal     Hybrid Journal   (Followers: 28)
Health Policy     Hybrid Journal   (Followers: 48)
Health Policy and Technology     Hybrid Journal   (Followers: 5)
Health Policy OPEN     Open Access   (Followers: 1)
Health Promotion & Physical Activity     Open Access   (Followers: 9)
Health Promotion International     Hybrid Journal   (Followers: 27)
Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals     Full-text available via subscription   (Followers: 9)
Health Promotion Practice     Hybrid Journal   (Followers: 16)
Health Prospect     Open Access  
Health Psychology Review     Hybrid Journal   (Followers: 46)
Health Research Policy and Systems     Open Access   (Followers: 16)
Health SA Gesondheid     Open Access   (Followers: 2)
Health Science Reports     Open Access   (Followers: 1)
Health Sciences and Disease     Open Access   (Followers: 2)
Health Security     Hybrid Journal   (Followers: 1)
Health Services Insights     Open Access   (Followers: 1)
Health Systems     Hybrid Journal   (Followers: 6)
Health Systems & Reform     Open Access   (Followers: 3)
Health Voices     Full-text available via subscription  
Health, Culture and Society     Open Access   (Followers: 13)
Health, Risk & Society     Hybrid Journal   (Followers: 11)
Health, Safety and Environment     Open Access   (Followers: 35)
Healthcare     Open Access   (Followers: 2)
Healthcare Quarterly     Full-text available via subscription   (Followers: 9)
Healthcare Technology Letters     Open Access  
HERD : Health Environments Research & Design Journal     Full-text available via subscription   (Followers: 2)
Highland Medical Research Journal     Full-text available via subscription  
Hispanic Health Care International     Full-text available via subscription  
Histoire, médecine et santé     Open Access   (Followers: 1)
Home Health Care Services Quarterly     Hybrid Journal   (Followers: 5)
Hong Kong Journal of Social Work, The     Hybrid Journal   (Followers: 3)
Horizonte Medico     Open Access  
Hua Hin Sook Jai Klai Kangwon Journal     Open Access  
Human Nutrition & Metabolism     Open Access   (Followers: 2)
IEEE Journal of Translational Engineering in Health and Medicine     Open Access   (Followers: 5)
IISE Transactions on Occupational Ergonomics and Human Factors     Hybrid Journal  
IJS Global Health     Open Access  
Implementation Science     Open Access   (Followers: 25)
IMTU Medical Journal     Full-text available via subscription  
Indian Journal of Youth and Adolescent Health     Open Access  
Indonesian Journal of Public Health     Open Access  
interactive Journal of Medical Research     Open Access  

        1 2 3 4 | Last

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Galen Medical Journal
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ISSN (Print) 2228-5423 - ISSN (Online) 2322-2379
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  • Investigation of Kelussia odoratissima and Angelica sinensis similarities
           in zebrafish-based in-vivo bioactivity assays and their chemical
           composition

    • Authors: Mohammad Rezaei, Parisa Fooladi, Mohamad Norani, Alexander Crawford, Shahram Eisa-Beygi, Yaser Tahamtani, Mahdi Ayyari
      Pages: e2793 - e2793
      Abstract: Background: Kelussia odoratissima (KO) and Angelica sinensis (AS) have been used in their indigenous traditional medicine, for various diseases. This study was conducted to evaluate the volatile oil composition of KO leaves (KVL) and AS root (AVR) and biological activity of essential oils (EOs) and hydroalcoholic extracts of both plants using two different transgenic zebrafish (Danio rerio) models.
      Materials and Methods: Both EOs were isolated by hydrodistillation and analysed by GC and GC/MS. For viability tests, larvae were treated with different concentrations of extracts to determine an appropriate starting concentration. Hydroalcoholic extracts and EOs have been tested in a dose-dependent manner for their biological activity using tissue-specific transgenic zebrafish Tg(fli-1: EGFP) and Tg (ins: GFP-NTR) embryos and larvae. One-way ANOVA was used to compare the mean of pBC area and intersegmental vessels (ISVs) outgrowth between the treatment groups.
      Results: Eleven compounds were in common to both oils, comprising 51.3% of KVL and 61.7% of AVR, of which 39.3% in KVL and 37.6% in AVR were phthalide structures. Results revealed that both EOs blocked ISVs formation in the Tg (fli-1: EGFP) embryos increased to 10% of the control value, while both hydroalcoholic extracts did not show any anti-angiogenesis effects in these embryos. In addition, AVR has been shown to significantly induce PBC regeneration following ablation in the Tg (ins: GFP-NTR), but its regenerative activity was lower than that of 5′-N-ethylcarboxamidoadenosine (NECA) as a positive control. Taken together, the anti-angiogenesis activity of both EOs could be attributed to the phthalide structures while for the PBC regenerative activity, other compounds including β-Thujaplicinol, exclusively existing in AVR, might be effective.
      Conclusion: Although the genera, organs, and origin of these plants are different, their similar chemical composition and biological activities make them valuable resources for further investigation in basic medical and pharmaceutical science.    
      PubDate: 2023-07-30
      Issue No: Vol. 12 (2023)
       
  • Differential Association of Dietary Linoleic Acid and Alpha-linolenic Acid
           with Adipose Tissue in a Sample of Iranian Adults; A Cohort-based
           Cross-sectional Study

    • Authors: Esmail Karami, Saeid Hadi, Mohsen Mohit, Seyed Jalil Masoumi
      Pages: e3023 - e3023
      Abstract: Background: Overweight and obesity are the most critical risk factors for chronic diseases. The quality of dietary fatty acids as one of the factors affecting fat accumulation has received little attention. This study investigates the association between dietary linoleic acid (LA) and alpha-linolenic acid (ALA) with body fat indices in a sample of healthy Iranian adults.
      Materials and Methods: In this cohort-based cross-sectional study, 3,195 individuals aged 20 to 60 who participated in the Shiraz University of Medical Science Employees Health Cohort study were included. Dietary intake was assessed using a validated 118-item Food Frequency Questionnaire (FFQ), and body composition was assessed by the bioelectrical impedance analysis method. Multiple linear regression adjusted for relevant confounders was used to determine the associations.
      Results:  Mean dietary intake of LA was 14.20 ± 7.01 mg/day for men and 13.90 ± 6.71 mg/day for women. Additionally, the daily intake of ALA was 0.18 ± 0.18 mg/day in men and 0.17 ± 0.19 mg/day in women. Dietary intake of ALA for men had an inversely significant association with body fat mass (BFM) (β: -0.585, 95% CI: -1.137, -0.032, P=0.038), percentage of body fat (PBF) (β: -0.537, 95% CI: -0.945, -0.129, P=0.010), Visceral Fat Area (VFA) (β: -2.998, 95% CI: -5.695, -0.302, P=0.029), and Waist to Hip Ratio (WHR) (β: -0.689, 95% CI: -1.339, -0.040, P=0.038).
      Conclusion: Higher dietary ALA intake was associated with lower BFM, BFP, VAF, and WHR in men. The present study confirms that ALA intake should be considered a preventive treatment to improve body composition. However, further research is recommended in this regard.
      PubDate: 2023-07-29
      Issue No: Vol. 12 (2023)
       
  • ABO/Rh Blood Groups and the Temperament (Mizaj) Based on Traditional
           Persian Medicine Perspective: A Cross-sectional Study

    • Authors: Mohammad Mahdi Parvizi , Mohadeseh Molayemat, Maryam Rezaee , Babak Shirazi Yeganeh, Thomas Rampp, Mohammad Hashem Hashempur
      Pages: e3062 - e3062
      Abstract: Background: Mizaj is a fundamental concept in traditional Persian medicine (TPM) that explains the physiological and psychological traits of human beings. This study aimed to investigate the association between the ABO/Rh blood groups and the Mizaj.
      Materials and Methods: This cross-sectional study was conducted on 18-60 years old individuals who visited the Iranian Blood Transfusion Organization, Shiraz Branch. We used Mojahedi’s Mizaj questionnaire to determine the Mizaj of the participants. The participants’ blood group and Rh were determined based on the antibodies against types A, B, and Rh antigens of their blood.
      Results: We assessed 308 individuals consisting of 174 (56.49%) male and 134 (43.51%) female. The results of our study showed a significant relationship between the AB blood group and the cold Mizaj in both simple and compound Mizaj categories (P=0.012, P=0.014, respectively). Logistic regression analysis revealed that people with the AB blood group were 2.88 times more likely to have cold Mizaj than people with the O blood group (OR=2.88, 95% CI: 1.16 to 7.15). In addition, those with the A blood group were found to be 54% less likely to have a dry Mizaj than those with the O blood group (OR=0.46, 95% CI: 0.23 to 0.92). There was no significant association between the participants’ Mizaj and their Rh blood group (P>0.05).
      Conclusion: It seems that there was a significant relation between the AB blood group and cold Mizaj, as well as the A blood group and dry Mizaj. However, further studies are recommended with controlling the probable confounding factors.
      PubDate: 2023-07-15
      DOI: 10.31661/gmj.v12i.3062
      Issue No: Vol. 12 (2023)
       
  • Use of Smartphone-Based Video Directly Observed Therapy to Increase
           Tuberculosis Medication Adherence: An Interventional Study

    • Authors: Manal M. Al Daajani, Abdullah J. Alsahafi, Abdullah M. Algarni, Abdulhamed L. Moawwad, Ahmed A. Osman, Khalid Y.A. Algaali, Mohammed F. Abdalaziz, Muhammad A. Halwani, Shrooq M. Aldajani, Nazik M. H. Mohammed, Heassah S. Alshamrani, Mohammed N. Alshahrani, Ghadah M. Albostani, Rami S. Alzahrani, Saadiya O. Al Somali, Ibrahim Assiri, Naif G. Alshammari
      Pages: e3067 - e3067
      Abstract: Background: Tuberculosis (TB) treatment through Directly Observed Therapy (DOT) has an alternative form of video surveillance therapy (VOT) that utilizes the technological capabilities of smartphones to provide patients with low-cost access to doctors without impacting their work and personal life. We aimed to assess TB patients’ drug compliance, perceptions, and feasibility towards smartphone-based video direct observed therapy (VDOT) in Jeddah, KSA. Materials and Methods: We conducted a prospective non-randomized interventional study. We delivered smartphone-based VDOT among previously unstudied patients to monitor adherence to the treatment regimen. The expected total number of VDOT sessions was1200. We conducted post-intervention interviews to assess acceptability and satisfaction. Results: In this study, we included 20 participants, 16 of whom were males, with a mean age of 34.3 (±12.5) years. No side effects to the treatments were identified in all participants. The adherence rate for the total period was 93% and 99.5%, measured by the first and second methods, respectively. Most participants were satisfied with the VDOT experience, the time spent on sessions, and the approach’s privacy. Conclusion: This study provides promising results for the feasibility and effectiveness of smartphone-based VDOT for TB treatment to increase adherence which was indicated by a high compliance rate, acceptability, and high satisfaction level.
      PubDate: 2023-07-03
      DOI: 10.31661/gmj.v12i.3067
      Issue No: Vol. 12 (2023)
       
  • Characterization of Small Genetic Variants in Breast Cancer Cell Line
           Under Tamoxifen Therapy

    • Authors: Mahnaz Nezamivand-Chegini, Hamed Kharrati-Koopaee, Seyed Taghi Heydari, Hassan Giahi, Fatemeh Sabahi, Ali Dehshahri, Kamran Bagheri Lankarani
      Pages: e2598 - e2598
      Abstract: Background: Tamoxifen (TAM) is an effective hormone therapy that reduces the risk of cancer recurrence. According to evidence, TAM contributes to the alterations of genetic variants background and plays a role in the effectiveness of treatments via alteration of the genetic variants. The effects of TAM on genomic features were investigated in the current study by discovering genetic variants and finding the answer to the following question: “Is there any association between the alterations of genetic variants under TAM consumption and an effective treatment process'”
      Materials and Methods: Whole-transcriptome (RNA-seq) dataset from four investigations including 10 TAM-treated samples and 9 untreated samples as the control groups were derived from European Bioinformatics Institute (EBI). Using the process of variants calling, the differential genetic variants between and gene ontology enrichment analysis were detected by CLC Genomics Workbench (12).
      Results: Current study reported about 5.8 million genetic variants. The outcomes of the chi-square test showed that distributions of genetic variants between control and treated samples were significant (p<0.05). The genetic variants comparison between the control and TAM-treated samples indicated that there were 67 differential genetic variants. Gene ontology enrichment analysis indicated that differential genetic variants were associated with several tumor suppressors and oncogenes including IL6ST, GEN1, FNTA. HSPA5, NSMCE2, and DDX11.
      Conclusion: Most of the candidate genes with different genetic variants had dual roles as oncogenes or tumor suppressors. Therefore, it can be argued that TAM does not play a significant role in an effective treatment through alteration of the genetic variants. In other words, it cannot be concluded that the TAM therapy-resulted alterations of genetic variants play a positive or negative role in the treatment process.
      PubDate: 2023-06-26
      Issue No: Vol. 12 (2023)
       
  • Cytotoxic and Apoptotic Effects of Vanadyl Sulfate on MCF-7 Breast Cancer
           Cell Line

    • Authors: Maryam Dehdashti, Zahra Abbasy, Hamid Zaferani Arani, Hesam Adin Atashi, Seyed Alireza Salimi-Tabatabaee, Afsaneh Ghasemi, Zhila Fereidouni, Hadi Zare Marzouni, Habib Zakeri, Seyed Abbas Mirmalek
      Pages: e3050 - e3050
      Abstract: Background: Breast cancer (BC) is the major cause of death from cancer among women. Some studies have indicated the cytotoxic effects of vanadyl oxide sulfate (VOSO4). This study aimed to evaluate the anti-cancer effect of VOSO4 in the treatment of MCF-7 cell line. Materials and Method: The MCF-7 cell line was treated with different concentrations of VOSO4 for 24 and 48 hours. The measurement of cell death was performed by MTT assay. The cell apoptosis rate was measured using Annexin V/Propidium Iodide assay through flow cytometry. Also, the expression levels of p53, P21, Caspase8, superoxide dismutase type 1 (SOD1), Sod2, and Bcl2 mRNAs were evaluated, and Western blotting was performed for Sod1 protein. Results: The results showed that the half-maximal inhibitory concentration (IC50) for VOSO4 was 25 and 20 μg/ml for 24 and 48 hours, respectively. Indeed, VOSO4 has dose-dependent cytotoxic effects on the MCF-7. Also, the apoptosis of the cells after 24 hours of exposure to VOSO4 reached 52% compared with untreated cells. Moreover, after 24 hours of exposure to VOSO4 with IC50 concentration, the expression of p53, P21, Caspase8, Sod1, and Sod2 mRNAs increased (P<0.05), and the expression of Bcl2 mRNA was decreased (P<0.05). Also, the Western blotting revealed Sod1 protein level markedly increased following exposure to VOSO4 (P<0.05). Conclusion: Our results demonstrated that VOSO4 has an apoptotic and cytotoxic effect on BC cells. Therefore, it could be considered as a complementary agent for the medical treatment of patients with BC.
      PubDate: 2023-06-21
      DOI: 10.31661/gmj.v12i.3050
      Issue No: Vol. 12 (2023)
       
  • Heme Oxygenase-1 (HMOX1) Gene Polymorphisms, Thrombosis and COVID-19:
           Correspondence

    • Authors: Rujittika Mungmunpuntipantip, Viroj Wiwanitkit
      Pages: e2952 - e2952
      Abstract: -
      PubDate: 2023-06-14
      Issue No: Vol. 12 (2023)
       
  • Management of Chemotherapy Side Effects in Childhood Leukemia: Persian
           Medicine Experience

    • Authors: Babak Daneshfard, Amir Mohammad Jaladat, Majid Nimrouzi
      Pages: e2926 - e2926
      Abstract: -
      PubDate: 2023-06-10
      Issue No: Vol. 12 (2023)
       
  • Response to: Medical Ethics According to Avicenna’s Stance: A
           Synopsis

    • Authors: Hamed Arezaei, Majid Dadmehr
      Pages: e2794 - e2794
      Abstract: -  
      PubDate: 2023-06-10
      Issue No: Vol. 12 (2023)
       
  • Emerging Biomarkers of Acute Myocardial Infarction, An Overview of the
           Newest MicroRNAs

    • Authors: Venous Shahabi Raberi, Elnaz Javanshir, Mohsen Abbasnezhad, Sina Mashayekhi, Amirreza Abbasnezhad, Masumeh Ahmadzadeh, Akram Shariati
      Pages: e2909 - e2909
      Abstract: Globally, acute myocardial infarction (AMI) is the leading cause of death. Early and precise diagnosis is essential for medical care to enhance prognoses and reduce mortality. The diagnosis of AMI relies primarily on conventional circulating biomarkers. However, these markers have many drawbacks. Non-coding RNAs (ncRNAs) form a significant fraction of the transcriptome and have been shown to be essential for many biological processes, including the pathogenesis of the disease. ncRNAs can be utilized as biomarkers due to their important role in the disease’s development. The current manuscript describes recent progress on the role of ncRNAs as new AMI biomarkers.
      PubDate: 2023-05-30
      Issue No: Vol. 12 (2023)
       
  • How Might Consideration of Cell Polarity Affect Daily Therapeutic
           Practices' A Literature Review

    • Authors: Hamid Reza Ravanbod
      Pages: e2970 - e2970
      Abstract: Background: In addition to biochemical gradients and transcriptional networks, cell behaviour is controlled by endogenous bioelectrical signals resulting from the action of ion channels and pumps. Cells are regulated not only by their own membrane resting potential (Vmem) but also by the Vmem of neighbouring cells, establishing networks through electrical synapses known as gap junctions. V mem is the primary factor in producing a polarity that can regulate cell assimilation of various substances. This article aimed to examine how cell polarity can change and how variations in cell polarity may lead to clinical demonstrations.
      Materials and Methods: Using Cochrane Central, PubMed, Scopus, Web of Science (WOS), and Embase, a comprehensive qualitative literature review was conducted from February 1, 2018, to February 1, 2023, to identify studies addressing bioelectric, cell polarity, and electroceuticals in patients with foot and ankle problems.
      Results: Out of 1,281 publications, 27 were included. One study investigated bioelectric wound-healing. Twenty-five studies examined bioelectric nerve cell growth, whereas one study evaluated bioelectricity-induced cellular differentiation in the treatment of arteriopathies.
      Conclusion: The author of this systematic review support addressing the predisposing factors and healing impediments for a disease, thereby enhancing the healing process and reducing the likelihood of recurrence or parallel conditions. This method of treatment has provided a summary of evidence indicating that cell polarity could be addressed for the treatment and prevention of most if not all, foot and ankle problems. However, owing to the limitations of V mem and bioelectricity measurement and the direct or indirect involvement of genetics and chemical gradients, further studies are required to confirm these results.
      PubDate: 2023-05-28
      Issue No: Vol. 12 (2023)
       
  • The Crosstalk Between Autophagy and MicroRNAs in Esophageal Carcinoma

    • Authors: Neda Gorjizadeh, Sahar Poudineh, Behnaz Barghgir, Mohammadreza Eghbali, Alireza Sarlak, Maryam poudineh
      Pages: e2903 - e2903
      Abstract: Esophageal cancer (EC) is considered one of the most prevalent and aggressive malignancies worldwide, with a variety of molecular alterations thought to contribute to its incidence, development, progression, and invasion. However, the exact underlying mechanism has not been elucidated. Autophagy is a highly conserved degradative and recycling process that can function with a dual role in either the progression or the treatment of EC. Since microRNAs (miRNAs) are described as upstream regulators capable of controlling both oncogenic pathways and autophagic flux, the present study has aimed to review the crosstalk between autophagy and miRNAs and the potential perspective of these mechanisms in EC prevention and treatment.
      PubDate: 2023-05-23
      Issue No: Vol. 12 (2023)
       
  • The Immunomodulation Role of Vaginal Microenvironment on Human
           Papillomavirus Infection

    • Authors: Lingyan Sun, Li Li, Wenxin Xu, Cen Ma
      Pages: e2991 - e2991
      Abstract: Background: Evidence suggests the role of the vaginal microbiome and microenvironment in the immunity state. The human papillomavirus (HPV) infection is widely dependent on the healthy vaginal microenvironment. Hence, this study aimed to investigate the role of the vaginal microenvironment in the rate of high-risk HPV (hr-HPV) infection. Materials and Methods: This cross-sectional study was performed on 512 women with hr-HPV positive (n=212) or negative (n=300) infection. The vaginal samples of women were examined regarding yeas and Gardnerella vaginalis infection. Also, Lactobacillus acidophilus, pH, and enzyme activity (such as catalase, proline aminopeptidase, and leucocyte esterase) were compared between the two groups. Also, the histopathological study was performed on the vaginal samples. Results: The higher rate of yeast and G. vaginalis infections as well as decreased L. acidophilus, were significantly observed in women with hr-HPV positive infection (P<0.001). Also, histopathological findings indicated that cervical intraepithelial neoplasia grade I-III and cervical cancer lesions were markedly higher in hr-HPV positive group compared with control women. Conclusion: The hr-HPV infection was markedly correlated to vaginal microenvironments, and it could a risk factor for the elevation of the rate of high-grade cervical lesions.
      PubDate: 2023-05-20
      DOI: 10.31661/gmj.v12i.2991
      Issue No: Vol. 12 (2023)
       
  • Sonoelastography and Lumbopelvic Muscle Stiffness in Patients with Low
           Back Pain: A Systematic Review

    • Authors: Hossein Rafsanjani Deh Qazi, Mohammad Ali Mohseni Bandpei, Nahid Rahmani
      Pages: e2465 - e2465
      Abstract: This study aimed to systematically review studies conducted on the application of sonoelastography (SE) to evaluate lumbopelvic muscle stiffness in patients with low back pain (LBP). All relevant articles were retrieved from the available electronic databases, including PubMed, Web of Science, Scopus, EMBASE, Cochrane library, and CINAHL, using the keywords “Sonoelastography”, “Elasticity Imaging Technique”, “Muscle Stiffness”, “Modulus Elasticity”, “Low Back Pain”. After initial searches, studies that met the inclusion criteria (i.e., published in English and sonoelastography were used to assess lumbopelvic muscle stiffness in both patients with LBP and healthy individuals) were enrolled. Also, any animal research, abstract of the seminar and/or conference, and/or non-English-language article were excluded. The quality of the studies was assessed using the Physiotherapy Evidence Database (PEDro) scale. In total, eight relevant studies were selected for review. Three studies were considered to have excellent quality, and five were considered fair quality using the PEDro scale. All reviewed studies have reported that SE can be considered a non-invasive method for quantifying changes in lumbopelvic muscle stiffness. Muscle stiffness was significantly higher in LBP patients compared to healthy persons, as well as across subgroups of LBP patients in various test postures (P˂0.05). Only one study was conducted on the reliability of SE in healthy individuals, while another examined the validity of SE imaging. The results of the present systematic review indicated that SE imaging is a reliable and valid tool to identify muscle changes that occur in patients with LBP and evaluate the effects of rehabilitation treatment.
      PubDate: 2023-05-14
      Issue No: Vol. 12 (2023)
       
  • Potential Regulatory Role of miR-21 on Alzheimer’s Disease by
           Targeting GSK-3β Signaling

    • Authors: Haojun Ding
      Pages: e3027 - e3027
      Abstract: Background: Alzheimer’s disease (AD) is the most important neurogenerative disorder with progressive dementia as its main clinical manifestation. The microRNAs (miRNAs) are identified as crucial modulators in AD progression. Nevertheless, the biological potential of miR-21 in AD is obscure. Hence, this study aimed to evaluate the possible role of miR-21 in the pathogenesis of AD via phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (AKT)/glycogen synthase kinase-3beta (GSK-3β) signaling. Materials and Methods: The miR-21 expression in the brain tissues of patients with AD, as well as normal brain tissues and Aβ1-42-stimulated SH-SY5Y cell line (AD model) was examined by in situ hybridization and quantitative real-time polymerase chain reaction. Also, the apoptosis-linked protein levels as well as programmed cell death 4 (PDCD4) were detected by western blot. Results: Our findings revealed that miR-21 was low expressed in the brain tissues of patients with AD and AD model (P<0.01). Also, the miR-21 overexpression could inhibit apoptosis of the AD model (P<0.01). Indeed, the miR-21 negatively regulated PDCD4 expression, which led to activated PI3K/AKT/GSK-3β signaling. Conclusion: Our study demonstrated that miR-21 cloud inhibits cell apoptosis in AD through the activation of PI3K/AKT/GSK-3β signaling pathway using inhibition of PDCD4 expression.
      PubDate: 2023-05-13
      DOI: 10.31661/gmj.v12i.3027
      Issue No: Vol. 12 (2023)
       
  • The Effects of Aroma on Apnea Attacks and Oxygen Saturation Among Preterm
           Infants: A Systematic Review and Meta-Analysis

    • Authors: Sanaz Rustaee , Rafat Rezapour-Nasrabad , Masumeh Ghazanfarpour , Saeedeh Piri , Seyedeh Fatemeh Moosavi Moqaddam , Arian Behdarvandi , Fatemeh Kafami Ladani , Ahmad Rahmah, Maryam Mirzaei
      Pages: e2846 - e2846
      Abstract: Researchers and clinicians need to be aware of procedures that are more adaptable to new and different environments in premature infants; therefore, it is important to conduct a comprehensive review of the effect of aromatherapy on apnea attacks and oxygen saturation (SpO2) in premature newborns. In this review, databases such as PubMed, Scopus, Web of Science, and Cochrane Library were systematically searched without language and time limitations up to November 1, 2022. Initially, 153 studies were founded, and after duplicate removal, title as well as full-text review, seven studies were enrolled in the final analysis. Studies indicated that aromatherapy with Rosa damascena, vanilla, and breast milk odors could significantly reduce apneas in preterm infants and improve SpO2 levels. Hence, aromatherapy could consider as an effective adjuvant treatment for the reduction of apnea attacks among preterm infants.
      PubDate: 2023-05-08
      DOI: 10.31661/gmj.v12i.2846
      Issue No: Vol. 12 (2023)
       
  • Evaluation of the Effect of Artemisia Absinthium L. Eye-Cream on
           Infra-Orbital Dark Circle: A Randomized, Double-Blind, Placebo-Controlled
           Clinical Trial

    • Authors: Hanan Hamdi, Laila Shirbeigi, Mitra Rahimzadeh, Alireza Firooz, Gholamreza Amin, Kazem Mousavizadeh , Arman Zargaran
      Pages: e2413 - e2413
      Abstract: Background: The relative darkening of the lower eyelid skin, often linked with dark circles, may make one seem tired and older than the actual age. Considering the recommendations in the sources of Persian medicine regarding Artemisia absinthium L., this clinical trial aimed to investigate the effectiveness of cream prepared from the aqueous extraction of A.absinthium for infra-orbital dark circles removal.
      Materials and Methods: In this double-blind controlled clinical trial, an eye cream is made with 20% of the aqueous extract of A.absinthium in the base of the cream. For standardization based on Artemisinin, the high-performance liquid chromatography (HPLC) method was used. In two drug and placebo groups, 60 patients were equally enrolled in the trial. Erythema and pigmentation were evaluated via Mexameter®.
      Results: The cream was standardized, including 1.29±0.02 µg/mg Artemisinin in the product. Finally, 21 and 24 patients in the drug and placebo groups completed the study, respectively. In these groups, the difference in the mean ± standard deviation (SD) delta erythema (DE), delta luminance (DL), erythema, and melanin factors before and after the research were significant (P<0.05).
      However, the rate of reduction of DE, Erythema, and Melanin and the rise of DL are more significant in the treatment group than in the placebo group. Furthermore, the mean values of DE and DL factors before the research were significantly different in the two groups (P<0.001), but after the investigation did not show a significant difference. The mean value of the Erythema factor in the two groups before (P=0.25) and after (P=0.5) did not show a significant difference. The mean value of Melanin after the research between the two groups showed a significant difference (P=0.01).
      Conclusion: The results show that the cream prepared from the herbal composition of Persian medicine improves the infra orbital dark circle around the eyes.
      [GMJ.2023;12:e2413]
      PubDate: 2023-04-26
      Issue No: Vol. 12 (2023)
       
  • Association between Elevated TNF-α Levels and Severe Malaria

    • Authors: Khalid Mohamedahmed
      Pages: e2927 - e2927
      Abstract: -
      PubDate: 2023-04-25
      Issue No: Vol. 12 (2023)
       
  • When Home Is Not a Safe Place: Confronting Domestic Violence During the
           COVID-19 Era

    • Authors: Nader Aghakhani, Mohammad Delirrad, Elham Jafari
      Pages: e2814 - e2814
      Abstract: -
      PubDate: 2023-04-25
      DOI: 10.31661/gmj.v12i.2814
      Issue No: Vol. 12 (2023)
       
  • Acute or Short-term Effects of Whey Protein Alone or Along with
           Carbohydrate on Inflammation: A Systematic Review of Clinical Trials

    • Authors: Ali Akbari, Mahsa Moazen, Siavash Babajafari, Seyedeh Maryam Abdollahzadeh, Maryam Ranjbar Zahedani, Najmeh Sasani, Asma Kazemi
      Pages: e2441 - e2441
      Abstract: Background: Excessive inflammatory response is associated with several diseases. Recently, there has been an increasing trend for investigation of the acute or short-term effects of whey protein alone or in combination with carbohydrates on inflammatory status, especially in athletes. This systematic review aimed to clarify these effects.
      Materials and Methods: PubMed, Scopus, and Web of Science databases were searched from January 1990 to September 2021, without language restriction. Adult studies examining the effects of whey protein alone or together with carbohydrates on interleukin-6, tumor necrosis factor-α, and C-reactive protein levels with a maximum duration of 15 days and with at least one comparison group were included. The quality of studies was analyzed using the Cochrane risk of bias tool.
      Results: Twenty-five studies met the inclusion criteria. Significant reductions in inflammatory markers was observed in seven out of 25 studies (28%). However, one out of 25 studies (4%) reported a significant increase in inflammatory status. Among those studies comparing the effects of whey protein alone with non-protein or protein-containing groups, 18.18% (two out of 11) and 10% (one out of ten) of the trials revealed a significant decrease in the markers, respectively. Moreover, of those studies comparing whey protein plus carbohydrate with non-protein or protein-containing groups, 33.33% (two out of six) and 40% (two out of five) of them showed a significant reduction in the inflammatory response, respectively. The quality of the majority of studies (84%) was poor.
      Conclusion: It seems that whey protein alone or the combination of it with carbohydrates may not affect the inflammatory markers in the short run (PROSPERO registration number: CRD42021273915).[GMJ.2023;12:e2441]
      PubDate: 2023-04-18
      DOI: 10.31661/gmj.v12i.2441
      Issue No: Vol. 12 (2023)
       
  • The Network between Heart and Liver from the View of Persian Medicine
           Versus Conventional Medicine

    • Authors: Azadeh Zarei, Mehrdad Karimi, Hossein Rezaeizadeh
      Pages: e2557 - e2557
      Abstract: Background: Liver and Heart are two important organs in the human body, whose function strongly affects other organs. On the other hand, these two main organs affect each other due to common metabolic pathways. Therefore, a disorder in any of them can lead to disease in other organs. Today, using the network medicine perspective, these complex connections can be easily mapped and discovered. From the Persian medicine viewpoint, links are formed based on the material causes of diseases, while from the conventional medicine viewpoint, they are mostly formed due to metabolites, genes, and pathways. Materials and methods: In this article, we first investigated the recent articles of conventional medicine that examine the relationship between Heart and Liver in the important databases. Then we checked out the sources of Persian medicine and finally, using the RStudio software used in network medicine for text mining, we drew the communication network centered on Heart and liver and their mutual causes from the perspective of Persian Medicine. Results: Examining the network connection between the heart and the liver showed that the definitions based on Persian medicine, which are based on the material causes of diseases, are very compatible with the genes, metabolites and pathways between these two organs. Conclusion: understanding these concepts can be helpful in detecting the co-occurrence of diseases of these two organs, as well as predicting the possible occurrence of related diseases between the heart and liver, and ultimately in better treatment.
      [GMJ.2023;12:e2557]
      PubDate: 2023-04-18
      DOI: 10.31661/gmj.v12i.2557
      Issue No: Vol. 12 (2023)
       
  • Association of Long Non-Coding RNA Malat1 with Serum Levels of
           Interleukin-1 Beta and Vitamin D in Patients with Ischemic Stroke

    • Authors: Mahnaz Bayat, Reza Tabrizi, Mohammad Saied Salehi, Najmeh Karimi, Moosa Rahimi, Etrat Hooshmandi, Niloufar Razavi moosavi, Nima Fadakar, Afshin Borhani-Haghighi
      Pages: e2457 - e2457
      Abstract: Background:Previous studies have demonstrated the strong association of inflammatory cytokines and vitamin D (VitD) deficiency and ischemic stroke (IS) pathogenesis. Due to the negative correlation between long non-coding RNA (lncRNA) Malat1 and pro-inflammatory factors we decided to investigate the associations between Malat1 expression with serum interleukin-1β (IL-1β), and VitD levels in IS patients. Materials and Methods:In this cross-sectional study, 63 IS patients were included. We used enzyme-linked immunosorbent assays to evaluate the serum levels of VitD and IL-1β. Malat1 expression was evaluated by the real-time polymerase chain reaction test. The associations between Malat1expression with VitD and IL-1β were analysed with linear regression (Stepwise model) and Pearson’s correlation analysis. Results: The Malat1 expression was inversely correlated with stroke severity (r=-0.25, P=0.043). Stepwise regression analysis showed a significant positive relationship between VitD level and Malat1 expression (Beta=0.28, P=0.02), and also showed a non-significant negative relationship between IL-1β and stroke severity. VitD level showed a positive Pearson correlation with Malat1 (r=0.28, P=0.023) and a negative correlation with IL-1β (r=-0.29, P=0.018) while it could not detect a significantly negative correlation with stroke severity. Conclusion: For the first time the associations between Malat1 expression with IL-1β and VitD in IS patients was analyzed. We found a significant positive relationship between VitD and Malat1. This correlation needs to be investigated with a larger sample size to achieve a strong and reliable association between VitD and Malat1.[GMJ.2023;12:e2457]
      PubDate: 2023-02-26
      DOI: 10.31661/gmj.v12i.2457
      Issue No: Vol. 12 (2023)
       
  • Icariin, A Novel Promising Complementary Therapeutic Strategy In The
           Management Of Female Infertility: A Literature Review

    • Authors: Sima Mosavi, Amirabbas Rostami, Marzieh Pooladi, Mahdie ShojaeiBaghini, Sahar Poudineh, Maryam Poudineh, Esmaeil Behzadi
      Pages: e2528 - e2528
      Abstract: The prevalence of pre-menopausal female infertility is increasing considerably due to various causes such as environmental pollutants, increased administration of chemotherapeutics and radiation exposure, microbial infections, and genetic/epigenetic alterations. However, the current therapeutical strategies remain unfavorite as the disadvantages are strongly challenging. Icariin (ICI) is a phytoestrogen that exerts some promising properties in order to alleviate female infertility. Therefore, the current literature review aimed to evaluate the conducted studies regarding the beneficial impacts of ICI on the female reproductive system and female fecundity. The findings of the present study revealed that ICI is able to modulate the levels of reproductive hormones as it causes a significant decrement in the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) while increasing the levels of estrogen and progesterone. Furthermore, the administration of ICI results in a dramatic alteration in the expression of sex steroids’ receptors, particularly in female reproductive tissues. In addition, preserving ovarian follicular reserve, improving the ovarian and uterine histoarchitecture, elongating the estrous cycle duration, and eventually advancing the female fecundity are other major effects of ICI on the female reproductive system. Despite these desired beneficial properties, the current knowledge appears to be insufficient, hence further investigations, particularly on humans, are encouraged. To the best of our knowledge, this review provides a comprehensive information regarding the beneficial effects of Icariin on female infertility for the firs time
      PubDate: 2023-02-17
      DOI: 10.31661/gmj.v12i.2528
      Issue No: Vol. 12 (2023)
       
  • Dysregulation of miR-577, miR-505-3p, miR-3682-3p and miR-4661 in breast
           cancer patients, differentially expression in ER-positive compared to
           ER-negative

    • Authors: Arman Moradi, Saeid Rahmani, Narges Jafarbeik Iravani, Rezvan Esmaeili, Seyed Javad Mowla, Keivan Majid Zadeh
      Pages: e2540 - e2540
      Abstract: It is proved that the breast cancer is one of the most common cancers and the second leading cause of cancer-related death in women. Approximately 75 % of all breast cancers is ER-positive which is highly responsive to endocrine therapy. MicroRNAs (miRNAs) are short non-coding RNA that have a pivotal role in mammal cells by regulating gene expression. The expression of miRNAs is different in the various subtypes of breast cancer, and the expression profile of miRNAs can be informative in the classification of breast cancer. In this study, after extraction of total RNA and synthesis of cDNA expression of miR-577, -505-3p, -3682-3p and -4661-5p were investigated respectively in eighteen breast cancer samples of both ER+ and ER- types and eighteen normal adjacent tissues by Real-Time PCR. Downregulation of miR-577 and miR-505-3p was detected in breast cancer samples. Expression of miR-577 and miR-505-3p significantly decreased in ER+ subtype compared to that of ER- subtype. Data has showed upregulation of miR-3682-3p and miR-4661-5p in breast cancer tissue. The expression level of this miRNA was higher in ER- subtype than that of the ER+ subtype. ROC analysis demonstrated that both miR-577 and miR-505-3p have an acceptable diagnostic value in diagnosing breast cancer and differentiation of various types of breast cancer. MiR-3682-3p has had a relatively proper diagnostic value in diagnosing breast cancer but it does not have adequate diagnostic power to discriminate the different subtypes of breast cancer. The data obtained from the present study revealed that both miR-577 and miR-505-3p could be used as a biomarker in diagnosing different subtypes of breast cancer.
      PubDate: 2023-02-17
      DOI: 10.31661/gmj.v12i.2540
      Issue No: Vol. 12 (2023)
       
  • Quantitative Assessment of PALB2 and BRIP1 Genes Expression in the Breast
           Cancer Cell Line under the Influence of Tamoxifen

    • Authors: Hamed Kharrati-Koopaee, Seyed Taghi Heydari, Mehdi Dianatpour, Kamran Bagheri Lankarani
      Pages: e2483 - e2483
      Abstract: Background:Breast cancer is considered one of the leading causes of mortality in the world. Cancer incidence and consequently, drug consumption can strongly influence gene expressions at the transcriptome level. Therefore, the assessment of the candidate biomarkers’ gene expression can accelerate the diagnosis process and increase the chance of treatment and remission. In this regard, the quantitative assessment of Partner and localizer of BRCA2 (PALB2) and BRCA1 Interacting Helicase 1 (BRIP1) genes expression in the breast cancer cell line under the treatment of Tamoxifen (TAM) was executed in this study. Materials and Methods :MCF7 cells were cultured as TAM-treated and control groups. RNA extraction and cDNA synthesis were performed based on the instructions of provided kits. qPCR Hi-ROX Master Mix kit was applied to the Quantitative Real-Time Polymerase Chain Reaction (Q-PCR). The outputs of Q-PCR were analyzed by REST statistical software. Results:Outcomes derived from data analysis of BRIP1 gene expression did not show any significant difference between the gene expression of control and TAM-treated groups. The expression of PALB2 was significantly higher in the TAM-treated group compared to the control group (P<0.05). Conclusion:Our findings showed a significant alteration between PALB2 gene expression in the TAM-treated breast cancer cell line and the control cell line. The quantitative assessment of mentioned genes as possible markers could be considered a non-invasive method for breast cancer in the processes of prognostic evaluations, screening, and treatment monitoring.
      PubDate: 2023-02-17
      DOI: 10.31661/gmj.v12i.2483
      Issue No: Vol. 12 (2023)
       
  • Mental Health Status of Healthcare Workers During the Coronavirus Disease
           2019 Pandemic: A Survey of Hospitals in Shiraz, Iran

    • Authors: Arash Mani, Mani Kharazi, Mohammad Reza Yousefi, Ali Akbary, Morteza Banakar, Hossein Molavi Vardanjani, Leila Zarei, Mohammad Khabaz Shirazi, Seyed Taghi Heydari, Kamran Bagheri Lankarani
      Pages: e2512 - e2512
      Abstract: Background:Healthcare workers (HCWs) directly or indirectly involved in the coronavirus disease 2019 (COVID-19) treatment process may experience severe mental consequences of the pandemic. Hence, this study aimed to evaluate the mental health status of HCWs in hospitals affiliated with Shiraz University of Medical Sciences, Iran. Materials and Method:This cross-sectional study was performed on 503 HCWs from five hospitals in Shiraz, including one COVID-19 front-line hospital, two COVID-19 second-line hospitals, and two without COVID-19 wards. Then, to assess the levels of anxiety, depression, insomnia, and post-traumatic stress disorder (PTSD) among HCWs, the Persian versions of the Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI), and Global Psychotrauma Screen (GPS) questionnaires were placed, respectively. Results:The mean age of participants was 33.94±8.26 years, and 252 (50.1%) were females. Anxiety, depression, insomnia, and moderate to high levels of PTSD were observed in 40.4%, 37.8%, 24.5%, and 71% of participants, respectively. A history of mental disorders was associated with all four outcomes (P<0.05). Females gender and living with elderly and/or children were correlated with anxiety and PTSD (P<0.05). Working at COVID-19 front- and second-line hospitals were similarly linked to higher insomnia and PTSD levels (P<0.05). Also, working in COVID-19 wards or non-clinical settings was associated with anxiety and depression (P<0.05). Conclusion:Most of the HCWs in this study may experience mental difficulties. Some factors may increase their risk of experiencing these difficulties. Hence, in the crisis era, mental health monitoring and identification of groups with predisposing factors are required to provide appropriate care as quickly as feasible.
      PubDate: 2023-02-17
      DOI: 10.31661/gmj.v12i.2512
      Issue No: Vol. 12 (2023)
       
  • Diagnostic Value of Blood Oxygen Saturation and C-Reactive Protein (CRP)
           in Predicting Lung Sequels in COVID-19 Infected Patients Admitted to
           Hospital: A 12-week Cohort Study

    • Authors: Samaneh Abiri, Mina Mohammadizadeh, Lohrasb Taheri, Seyed Reza Mousavi, Masihallah Shakeri, Elahe Rahmanian, Naser Hatami, Erfan Ghanbarzadeh, Zhila Rahmanian, Navid Kalani
      Pages: e2695 - e2695
      Abstract: Background: Evidence of COVID-19 respiratory sequels is restricted and predisposing factors are not well studied more than two years passing pandemic. This study followed COVID-19 patients 12 weeks after discharge from hospital for respiratory sequels. Materials and Methods: This was a prospective study on discharged COVID-19 patients in 2021, in Jahrom, Iran. Exposure was COVID-19 clinical features at hospitalization, including symptoms and physical examination and laboratory findings, and primary endpoint was 12-week lung sequel, being evaluated by a chest CT scan. Demographics and previous medical history were considered covariates. SPO2 and CRP  6-week changes were followed as an early tool for prediction of 12-week lung sequel. Results: Totally, 383 participants (17 had sequels) with mean age of 57.43±18.03 years old (50.13% male) completed 12-week study follow-ups. Ninety-one (23.8%) subjects had an ICU admission history.  SPO2% in 6th week was statistically significantly associated with a higher rate of 12-week sequelae (p<0.001). Also, patients having CT scan scores between 40% to 50%  (p=0.012)  and higher than 50% (p=0.040) had higher chance of experiencing lung sequelae than patients with CT scan score of below 40%, as well as having ICU admission history and lower SPO2% at 6th week of discharge.  There was a statistically significant increasing trend of SPO2% (P<0.001) and a statistically significant decreasing trend of CRP levels (P<0.001), overall. SPO2% increase after 6 weeks was lower in participants with lung sequels than fully improved ones (P=0.002) and as well as total 12-week change in SPO2% (P=0.001). CRP changes in none of evaluated periods were different among study groups (P>0.05). Conclusion: Our results were in favor of closely following SPO2 levels after patient discharge, while CRP assessment seems not helpful based on our results.
      PubDate: 2023-02-17
      DOI: 10.31661/gmj.v12i.2695
      Issue No: Vol. 12 (2023)
       
  • Early Postoperative Cardiac Complication Flowing Heart Transplantation

    • Authors: Sohrab Negargar, Sahar Sadeghi
      Pages: e2701 - e2701
      Abstract: Cardiovascular disorders remain the leading cause of death around the world. Heart transplantation is considered the only therapeutic choice defined as the gold standard strategy to manage end-stage heart failure. Nevertheless, the remaining postoperative complications compromise both the survival rate and quality of life in heart transplantation recipients. The present study aimed to review the current findings concerning the main early
      complications after heart transplantation, reliable predictors, diagnostic approaches, novel surgical techniques, and management strategies. The results demonstrated that significant advances in immunosuppressive pharmaceuticals, determining appropriate policies for donor acceptance, pre and post-operative treatment/care, selection of the most compatible donor with the recipient, and the suggestion of novel diagnostic and surgical techniques over the past decade had dropped the mortality and morbidity rates early after transplantation. However, arrhythmia, atrial flutter, atrial fibrillation, deep sternal wound infection along with other sites infections, low cardiac output syndrome, acute graft dysfunction, pericardial effusion, constrictive pericarditis, and acute cellular rejection could be considered as the major early complications following heart transplantations that pivotally require further investigations.
      PubDate: 2023-02-16
      DOI: 10.31661/gmj.v12i.2701
      Issue No: Vol. 12 (2023)
       
 
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  Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (686 journals)                  1 2 3 4 | Last

Showing 1 - 200 of 203 Journals sorted alphabetically
ACM Transactions on Computing for Healthcare     Hybrid Journal  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Adultspan Journal     Hybrid Journal   (Followers: 1)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 11)
Advances in Public Health     Open Access   (Followers: 33)
Adversity and Resilience Science : Journal of Research and Practice     Hybrid Journal   (Followers: 3)
African Health Sciences     Open Access   (Followers: 7)
African Journal of Health Professions Education     Open Access   (Followers: 7)
Afrimedic Journal     Open Access   (Followers: 3)
Ageing & Society     Hybrid Journal   (Followers: 40)
Aging and Health Research     Open Access   (Followers: 5)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
Akademika     Open Access  
American Journal of Family Therapy     Hybrid Journal   (Followers: 8)
American Journal of Health Economics     Full-text available via subscription   (Followers: 26)
American Journal of Health Education     Hybrid Journal   (Followers: 37)
American Journal of Health Promotion     Hybrid Journal   (Followers: 23)
American Journal of Health Sciences     Open Access   (Followers: 11)
American Journal of Preventive Medicine     Hybrid Journal   (Followers: 33)
American Journal of Public Health     Full-text available via subscription   (Followers: 226)
American Journal of Public Health Research     Open Access   (Followers: 33)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 9)
Annals of Health Law     Open Access   (Followers: 7)
Applied Biosafety     Hybrid Journal   (Followers: 2)
Applied Ergonomics     Hybrid Journal   (Followers: 18)
Archives of Suicide Research     Hybrid Journal   (Followers: 13)
Archivos de Prevención de Riesgos Laborales     Open Access  
ASA Monitor     Full-text available via subscription   (Followers: 15)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 7)
Asia Pacific Journal of Health Management     Full-text available via subscription   (Followers: 4)
Asia-Pacific Journal of Public Health     Hybrid Journal   (Followers: 12)
Asian Journal of Gambling Issues and Public Health     Open Access   (Followers: 5)
Asian Journal of Medicine and Health     Open Access   (Followers: 1)
Atención Primaria     Open Access   (Followers: 2)
Atención Primaria Práctica     Open Access   (Followers: 1)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 5)
Australian Family Physician     Full-text available via subscription   (Followers: 2)
Australian Indigenous HealthBulletin     Free   (Followers: 5)
Autism & Developmental Language Impairments     Open Access   (Followers: 18)
Bijzijn XL     Hybrid Journal  
Biomedical Safety & Standards     Full-text available via subscription   (Followers: 7)
Biosafety and Health     Open Access  
Biosalud     Open Access  
BMC Oral Health     Open Access   (Followers: 5)
BMC Pregnancy and Childbirth     Open Access   (Followers: 20)
Brazilian Journal of Medicine and Human Health     Open Access  
British Journal of Health Psychology     Hybrid Journal   (Followers: 56)
Cadernos de Educação, Saúde e Fisioterapia     Open Access  
Cadernos de Saúde     Open Access  
Cambridge Quarterly of Healthcare Ethics     Hybrid Journal   (Followers: 13)
Canadian Journal of Community Mental Health     Full-text available via subscription   (Followers: 16)
Canadian Journal of Human Sexuality     Hybrid Journal   (Followers: 1)
Canadian Journal of Public Health     Hybrid Journal   (Followers: 30)
Cannabis and Cannabinoid Research     Hybrid Journal   (Followers: 2)
Carta Comunitaria     Open Access  
Case Reports in Women's Health     Open Access   (Followers: 4)
Central Asian Journal of Global Health     Open Access   (Followers: 2)
CES Medicina     Open Access  
CES Salud Pública     Open Access  
Child and Adolescent Obesity     Open Access   (Followers: 9)
Child's Nervous System     Hybrid Journal  
Childhood Obesity and Nutrition     Open Access   (Followers: 12)
Children     Open Access  
Ciencia & Salud     Open Access  
Ciencia & Trabajo     Open Access  
Ciencia y Salud     Open Access   (Followers: 1)
Cities & Health     Hybrid Journal   (Followers: 5)
Cleaner and Responsible Consumption     Open Access  
Clinical and Experimental Health Sciences     Open Access   (Followers: 1)
ClinicoEconomics and Outcomes Research     Open Access   (Followers: 1)
Clocks & Sleep     Open Access   (Followers: 2)
CME     Hybrid Journal   (Followers: 1)
Conflict and Health     Open Access   (Followers: 8)
Contact (CTC)     Open Access   (Followers: 2)
Contraception and Reproductive Medicine     Open Access   (Followers: 2)
Cuaderno de investigaciones: semilleros andina     Open Access  
Current Opinion in Behavioral Sciences     Hybrid Journal   (Followers: 11)
Current Opinion in Environmental Science & Health     Hybrid Journal  
Das österreichische Gesundheitswesen ÖKZ     Hybrid Journal   (Followers: 2)
Day Surgery Australia     Full-text available via subscription   (Followers: 2)
Design for Health     Hybrid Journal   (Followers: 1)
Digital Health     Open Access   (Followers: 10)
Disaster Medicine and Public Health Preparedness     Hybrid Journal   (Followers: 12)
Discover Social Science and Health     Open Access   (Followers: 18)
Diversity and Equality in Health and Care     Open Access   (Followers: 10)
Diversity of Research in Health Journal     Open Access   (Followers: 1)
Dramatherapy     Hybrid Journal   (Followers: 2)
Drogues, santé et société     Open Access   (Followers: 2)
Early Childhood Research Quarterly     Hybrid Journal   (Followers: 26)
East African Journal of Public Health     Full-text available via subscription   (Followers: 3)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 24)
EcoHealth     Hybrid Journal   (Followers: 6)
Egyptian Journal of Nutrition and Health     Open Access   (Followers: 9)
Egyptian Journal of Occupational Medicine     Open Access   (Followers: 5)
electronic Journal of Health Informatics     Open Access   (Followers: 7)
ElectronicHealthcare     Full-text available via subscription   (Followers: 2)
Emerging Trends in Drugs, Addictions, and Health     Open Access   (Followers: 2)
Environmental Sciences Europe     Open Access   (Followers: 2)
Epidemics     Open Access   (Followers: 7)
EsSEX : Revista Científica     Open Access  
Ethics & Human Research     Hybrid Journal   (Followers: 4)
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 9)
Ethiopian Journal of Health Development     Open Access   (Followers: 7)
Ethiopian Journal of Health Sciences     Open Access   (Followers: 6)
Ethnicity & Health     Hybrid Journal   (Followers: 17)
EUREKA : Health Sciences     Open Access  
European Journal of Health Communication     Open Access  
European Journal of Investigation in Health, Psychology and Education     Open Access   (Followers: 5)
European Medical, Health and Pharmaceutical Journal     Open Access   (Followers: 2)
Evaluation & the Health Professions     Hybrid Journal   (Followers: 12)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exploratory Research in Clinical and Social Pharmacy     Open Access   (Followers: 4)
F&S Reports     Open Access   (Followers: 2)
Face à face     Open Access  
Family & Community Health     Hybrid Journal   (Followers: 12)
Family Relations     Partially Free   (Followers: 12)
FASEB BioAdvances     Open Access   (Followers: 3)
Fatigue : Biomedicine, Health & Behavior     Hybrid Journal   (Followers: 3)
Finnish Journal of eHealth and eWelfare : Finjehew     Open Access  
Food and Public Health     Open Access   (Followers: 11)
Food Hydrocolloids for Health     Open Access  
Food Quality and Safety     Open Access   (Followers: 2)
Frontiers in Digital Health     Open Access   (Followers: 4)
Frontiers of Health Services Management     Partially Free   (Followers: 7)
Gaceta Sanitaria     Open Access   (Followers: 2)
Ganesha Journal     Open Access  
Geospatial Health     Open Access   (Followers: 1)
Gestão e Desenvolvimento     Open Access  
Gesundheitsökonomie & Qualitätsmanagement     Hybrid Journal   (Followers: 7)
Giornale Italiano di Health Technology Assessment     Full-text available via subscription  
Global Advances in Health and Medicine     Open Access  
Global Challenges     Open Access   (Followers: 2)
Global Health : Science and Practice     Open Access   (Followers: 7)
Global Health Annual Review     Open Access   (Followers: 2)
Global Health Innovation     Open Access   (Followers: 3)
Global Health Journal     Open Access   (Followers: 2)
Global Health Promotion     Hybrid Journal   (Followers: 16)
Global Journal of Health Science     Open Access   (Followers: 6)
Global Medical & Health Communication     Open Access   (Followers: 1)
Global Mental Health     Open Access   (Followers: 13)
Global Reproductive Health     Open Access   (Followers: 1)
Global Security : Health, Science and Policy     Open Access   (Followers: 1)
Global Transitions     Open Access   (Followers: 1)
Globalization and Health     Open Access   (Followers: 7)
Hacia la Promoción de la Salud     Open Access  
Hastane Öncesi Dergisi     Open Access  
Hastings Center Report     Hybrid Journal   (Followers: 7)
HEADline     Hybrid Journal  
Health & Place     Hybrid Journal   (Followers: 23)
Health & Justice     Open Access   (Followers: 5)
Health : An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine     Hybrid Journal   (Followers: 21)
Health and Social Care Chaplaincy     Hybrid Journal   (Followers: 10)
Health and Social Work     Hybrid Journal   (Followers: 63)
Health Behavior and Policy Review     Full-text available via subscription   (Followers: 5)
Health Behavior Research     Open Access   (Followers: 2)
Health Care Analysis     Hybrid Journal   (Followers: 13)
Health Equity     Open Access   (Followers: 4)
Health Information Management Journal     Hybrid Journal   (Followers: 28)
Health Policy     Hybrid Journal   (Followers: 48)
Health Policy and Technology     Hybrid Journal   (Followers: 5)
Health Policy OPEN     Open Access   (Followers: 1)
Health Promotion & Physical Activity     Open Access   (Followers: 9)
Health Promotion International     Hybrid Journal   (Followers: 27)
Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals     Full-text available via subscription   (Followers: 9)
Health Promotion Practice     Hybrid Journal   (Followers: 16)
Health Prospect     Open Access  
Health Psychology Review     Hybrid Journal   (Followers: 46)
Health Research Policy and Systems     Open Access   (Followers: 16)
Health SA Gesondheid     Open Access   (Followers: 2)
Health Science Reports     Open Access   (Followers: 1)
Health Sciences and Disease     Open Access   (Followers: 2)
Health Security     Hybrid Journal   (Followers: 1)
Health Services Insights     Open Access   (Followers: 1)
Health Systems     Hybrid Journal   (Followers: 6)
Health Systems & Reform     Open Access   (Followers: 3)
Health Voices     Full-text available via subscription  
Health, Culture and Society     Open Access   (Followers: 13)
Health, Risk & Society     Hybrid Journal   (Followers: 11)
Health, Safety and Environment     Open Access   (Followers: 35)
Healthcare     Open Access   (Followers: 2)
Healthcare Quarterly     Full-text available via subscription   (Followers: 9)
Healthcare Technology Letters     Open Access  
HERD : Health Environments Research & Design Journal     Full-text available via subscription   (Followers: 2)
Highland Medical Research Journal     Full-text available via subscription  
Hispanic Health Care International     Full-text available via subscription  
Histoire, médecine et santé     Open Access   (Followers: 1)
Home Health Care Services Quarterly     Hybrid Journal   (Followers: 5)
Hong Kong Journal of Social Work, The     Hybrid Journal   (Followers: 3)
Horizonte Medico     Open Access  
Hua Hin Sook Jai Klai Kangwon Journal     Open Access  
Human Nutrition & Metabolism     Open Access   (Followers: 2)
IEEE Journal of Translational Engineering in Health and Medicine     Open Access   (Followers: 5)
IISE Transactions on Occupational Ergonomics and Human Factors     Hybrid Journal  
IJS Global Health     Open Access  
Implementation Science     Open Access   (Followers: 25)
IMTU Medical Journal     Full-text available via subscription  
Indian Journal of Youth and Adolescent Health     Open Access  
Indonesian Journal of Public Health     Open Access  
interactive Journal of Medical Research     Open Access  

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