Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (686 journals)                  1 2 3 4 | Last

Showing 1 - 200 of 203 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 1)
ACM Transactions on Computing for Healthcare     Hybrid Journal  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Adultspan Journal     Hybrid Journal   (Followers: 1)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 11)
Advances in Public Health     Open Access   (Followers: 30)
Adversity and Resilience Science : Journal of Research and Practice     Hybrid Journal   (Followers: 3)
African Health Sciences     Open Access   (Followers: 7)
African Journal of Health Professions Education     Open Access   (Followers: 6)
Afrimedic Journal     Open Access   (Followers: 3)
Ageing & Society     Hybrid Journal   (Followers: 40)
Aging and Health Research     Open Access   (Followers: 3)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 10)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
Akademika     Open Access  
American Journal of Family Therapy     Hybrid Journal   (Followers: 6)
American Journal of Health Economics     Full-text available via subscription   (Followers: 25)
American Journal of Health Education     Hybrid Journal   (Followers: 36)
American Journal of Health Promotion     Hybrid Journal   (Followers: 24)
American Journal of Health Sciences     Open Access   (Followers: 11)
American Journal of Health Studies     Full-text available via subscription   (Followers: 14)
American Journal of Preventive Medicine     Hybrid Journal   (Followers: 34)
American Journal of Public Health     Full-text available via subscription   (Followers: 208)
American Journal of Public Health Research     Open Access   (Followers: 31)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 9)
Annali dell'Istituto Superiore di Sanità     Open Access  
Annals of Global Health     Open Access   (Followers: 10)
Annals of Health Law     Open Access   (Followers: 7)
Applied Biosafety     Hybrid Journal   (Followers: 2)
Applied Ergonomics     Hybrid Journal   (Followers: 18)
Apuntes Universitarios     Open Access   (Followers: 1)
Archives of Community Medicine and Public Health     Open Access   (Followers: 2)
Archives of Medicine and Health Sciences     Open Access   (Followers: 5)
Archives of Suicide Research     Hybrid Journal   (Followers: 11)
Archivos de Prevención de Riesgos Laborales     Open Access  
ASA Monitor     Full-text available via subscription   (Followers: 18)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 7)
Asia Pacific Journal of Health Management     Full-text available via subscription   (Followers: 4)
Asia-Pacific Journal of Public Health     Hybrid Journal   (Followers: 11)
Asian Journal of Gambling Issues and Public Health     Open Access   (Followers: 5)
Asian Journal of Medicine and Health     Open Access   (Followers: 1)
Asian Journal of Population Sciences     Open Access   (Followers: 9)
Asian Journal of Social Health and Behavior     Open Access   (Followers: 3)
Atención Primaria     Open Access   (Followers: 2)
Atención Primaria Práctica     Open Access  
Australasian Journal of Paramedicine     Open Access   (Followers: 8)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 5)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Indigenous HealthBulletin     Free   (Followers: 4)
Autism & Developmental Language Impairments     Open Access   (Followers: 15)
Bijzijn XL     Hybrid Journal  
Biograph-I : Journal of Biostatistics and Demographic Dynamic     Open Access   (Followers: 1)
Biomedical Safety & Standards     Full-text available via subscription   (Followers: 7)
Biosafety and Health     Open Access  
Biosalud     Open Access  
Birat Journal of Health Sciences     Open Access  
BLDE University Journal of Health Sciences     Open Access   (Followers: 1)
BMC Oral Health     Open Access   (Followers: 5)
BMC Pregnancy and Childbirth     Open Access   (Followers: 19)
Brazilian Journal of Medicine and Human Health     Open Access  
British Journal of Health Psychology     Hybrid Journal   (Followers: 52)
Buletin Penelitian Kesehatan     Open Access  
Buletin Penelitian Sistem Kesehatan     Open Access  
Cadernos de Educação, Saúde e Fisioterapia     Open Access  
Cadernos de Saúde     Open Access  
Cambridge Quarterly of Healthcare Ethics     Hybrid Journal   (Followers: 13)
Canadian Family Physician     Partially Free   (Followers: 14)
Canadian Journal of Community Mental Health     Full-text available via subscription   (Followers: 16)
Canadian Journal of Human Sexuality     Hybrid Journal   (Followers: 1)
Canadian Journal of Public Health     Hybrid Journal   (Followers: 26)
Cannabis and Cannabinoid Research     Hybrid Journal   (Followers: 1)
Carta Comunitaria     Open Access  
Case Reports in Women's Health     Open Access   (Followers: 4)
CASUS : Revista de Investigación y Casos en Salud     Open Access  
Central Asian Journal of Global Health     Open Access   (Followers: 2)
CES Medicina     Open Access  
CES Salud Pública     Open Access  
Child and Adolescent Obesity     Open Access   (Followers: 3)
Child's Nervous System     Hybrid Journal  
Childhood Obesity and Nutrition     Open Access   (Followers: 11)
Children     Open Access  
Chinese Journal of Physiology     Open Access   (Followers: 2)
CHRISMED Journal of Health and Research     Open Access   (Followers: 1)
Christian Journal for Global Health     Open Access   (Followers: 1)
Ciencia & Salud     Open Access  
Ciencia & Trabajo     Open Access  
Ciencia e Innovación en Salud     Open Access  
Ciencia y Cuidado     Open Access   (Followers: 1)
Ciencia y Salud     Open Access   (Followers: 1)
Ciencia, Tecnología y Salud     Open Access  
Cities & Health     Hybrid Journal   (Followers: 5)
Cleaner and Responsible Consumption     Open Access  
Clinical and Experimental Health Sciences     Open Access   (Followers: 1)
ClinicoEconomics and Outcomes Research     Open Access   (Followers: 1)
Clocks & Sleep     Open Access   (Followers: 1)
CME     Hybrid Journal   (Followers: 1)
Community Health     Open Access   (Followers: 6)
Conflict and Health     Open Access   (Followers: 8)
Contact (CTC)     Open Access  
Contraception and Reproductive Medicine     Open Access   (Followers: 2)
Cuaderno de investigaciones: semilleros andina     Open Access  
Current Opinion in Behavioral Sciences     Hybrid Journal   (Followers: 10)
Current Opinion in Environmental Science & Health     Hybrid Journal  
D Y Patil Journal of Health Sciences     Open Access   (Followers: 4)
Das österreichische Gesundheitswesen ÖKZ     Hybrid Journal  
Day Surgery Australia     Full-text available via subscription   (Followers: 2)
Design for Health     Hybrid Journal   (Followers: 1)
Digital Health     Open Access   (Followers: 11)
Disaster Medicine and Public Health Preparedness     Hybrid Journal   (Followers: 12)
Discover Social Science and Health     Open Access   (Followers: 6)
Diversity and Equality in Health and Care     Open Access   (Followers: 10)
Diversity of Research in Health Journal     Open Access   (Followers: 1)
Dramatherapy     Hybrid Journal   (Followers: 2)
Drogues, santé et société     Open Access   (Followers: 2)
Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / Journal of Duzce University Health Sciences Institute     Open Access  
Early Childhood Research Quarterly     Hybrid Journal   (Followers: 23)
East African Journal of Public Health     Full-text available via subscription   (Followers: 3)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 25)
EcoHealth     Hybrid Journal   (Followers: 5)
Education for Health     Open Access   (Followers: 9)
electronic Journal of Health Informatics     Open Access   (Followers: 7)
ElectronicHealthcare     Full-text available via subscription   (Followers: 2)
Emerging Trends in Drugs, Addictions, and Health     Open Access   (Followers: 1)
Ensaios e Ciência : Ciências Biológicas, Agrárias e da Saúde     Open Access  
Environmental Disease     Open Access   (Followers: 3)
Environmental Sciences Europe     Open Access   (Followers: 2)
Epidemics     Open Access   (Followers: 7)
EsSEX : Revista Científica     Open Access  
Estudios sociales : Revista de alimentación contemporánea y desarrollo regional     Open Access  
Ethics & Human Research     Hybrid Journal   (Followers: 4)
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 7)
Ethiopian Journal of Health Development     Open Access   (Followers: 7)
Ethiopian Journal of Health Sciences     Open Access   (Followers: 6)
Ethnicity & Health     Hybrid Journal   (Followers: 16)
Eurasian Journal of Health Technology Assessment     Open Access   (Followers: 1)
EUREKA : Health Sciences     Open Access  
European Journal of Health Communication     Open Access  
European Journal of Investigation in Health, Psychology and Education     Open Access   (Followers: 5)
Evaluation & the Health Professions     Hybrid Journal   (Followers: 11)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Exploratory Research in Clinical and Social Pharmacy     Open Access  
Expressa Extensão     Open Access  
F&S Reports     Open Access  
Face à face     Open Access  
Families, Systems, & Health     Full-text available via subscription   (Followers: 8)
Family & Community Health     Hybrid Journal   (Followers: 13)
Family Medicine and Community Health     Open Access   (Followers: 8)
Family Relations     Partially Free   (Followers: 11)
FASEB BioAdvances     Open Access  
Fatigue : Biomedicine, Health & Behavior     Hybrid Journal   (Followers: 3)
Finnish Journal of eHealth and eWelfare : Finjehew     Open Access  
Food and Public Health     Open Access   (Followers: 10)
Food Hydrocolloids for Health     Open Access  
Food Quality and Safety     Open Access   (Followers: 2)
Frontiers in Digital Health     Open Access   (Followers: 4)
Frontiers in Neuroergonomics     Open Access  
Frontiers in Public Health     Open Access   (Followers: 8)
Frontiers of Health Services Management     Partially Free   (Followers: 6)
Gaceta Sanitaria     Open Access   (Followers: 2)
Galen Medical Journal     Open Access  
Ganesha Journal     Open Access  
Gazi Sağlık Bilimleri Dergisi     Open Access  
Geospatial Health     Open Access   (Followers: 1)
Gestão e Desenvolvimento     Open Access  
Gesundheitsökonomie & Qualitätsmanagement     Hybrid Journal   (Followers: 7)
Giornale Italiano di Health Technology Assessment     Full-text available via subscription  
Global Advances in Health and Medicine     Open Access  
Global Challenges     Open Access   (Followers: 2)
Global Health : Science and Practice     Open Access   (Followers: 7)
Global Health Annual Review     Open Access   (Followers: 2)
Global Health Innovation     Open Access   (Followers: 4)
Global Health Journal     Open Access   (Followers: 2)
Global Health Promotion     Hybrid Journal   (Followers: 15)
Global Journal of Health Science     Open Access   (Followers: 5)
Global Journal of Public Health     Open Access   (Followers: 16)
Global Medical & Health Communication     Open Access   (Followers: 1)
Global Mental Health     Open Access   (Followers: 13)
Global Reproductive Health     Open Access   (Followers: 1)
Global Security : Health, Science and Policy     Open Access   (Followers: 1)
Global Transitions     Open Access   (Followers: 1)
Global Transitions Proceedings     Open Access   (Followers: 1)
Globalization and Health     Open Access   (Followers: 7)
Hacia la Promoción de la Salud     Open Access  
Hastane Öncesi Dergisi     Open Access  
Hastings Center Report     Hybrid Journal   (Followers: 7)
HCU Journal     Open Access  
HEADline     Hybrid Journal  
Health & Place     Hybrid Journal   (Followers: 22)
Health & Justice     Open Access   (Followers: 5)
Health : An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine     Hybrid Journal   (Followers: 19)
Health and Human Rights     Open Access   (Followers: 10)
Health and Social Care Chaplaincy     Hybrid Journal   (Followers: 9)
Health and Social Work     Hybrid Journal   (Followers: 64)
Health Behavior and Policy Review     Full-text available via subscription   (Followers: 5)
Health Behavior Research     Open Access   (Followers: 2)
Health Care Analysis     Hybrid Journal   (Followers: 12)
Health Equity     Open Access   (Followers: 4)
Health Information : Jurnal Penelitian     Open Access  
Health Information Management Journal     Hybrid Journal   (Followers: 26)
Health Notions     Open Access  

        1 2 3 4 | Last

Similar Journals
Journal Cover
Galen Medical Journal
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2228-5423 - ISSN (Online) 2322-2379
Published by Shiraz University Homepage  [12 journals]
  • Expression Study of NDUFS1, NDUFV1, and NDUFV2 in Schizophrenia and
           Paranoid Personality Disorder

    • Authors: Arvin Haghighatfard, Mitra Salehi, Seyed Mehdi Saberi, Mehrdad Hashemi
      Abstract: Background: Schizophrenia (SCZ) is a major psychiatric disorder with unclear etiology and biological diagnosis. Paranoid personality disorder (PPD) is a type-A personality disorder characterized by paranoia and generalized mistrust. The etiology and molecular mechanisms of SCZ and PPD are not clarified. The present study aimed to examine the expression alteration of three major genes of mitochondrial complex I in the peripheral blood of patients with SCZ and PPD, and its correlations with clinical features of patients, especially the five major personality traits. Materials and Methods: This case-control study was performed on 735 SCZ, 742 PPD, and 750 non-psychiatric individuals. The mRNAs level of NDUFS1, NDUFV1, and NDUFV2 were assessed using quantitative real-time polymerase chain reaction, and their correlations with psychiatric symptoms were assessed by the positive and negative syndrome scale and the brief psychiatric rating scale tests, as well as personality traits that were evaluated by NEO Five-Factor Inventory. Results: Findings showed significant overexpression of NDUFS1, NDUFV1, and NDUFV2 in patients with SCZ (P=0.001, P=0.002, and P=0.004, respectively) and PPD (P=0.001, P=0.003, and P=0.006, respectively) compared with non-psychiatrists. In addition, these genes were associated with positive psychiatric symptoms and neuroticism in SCZ (P=0.008) and PPD (P=0.01). Conclusion: Overexpression genes that encode subunits of complex I play an important role in SCZ and PPD etiology and severity of symptoms. It may bring evidence about the significant role of bioenergetics dysfunction in psychotic behaviors in different psychiatric situations.
      PubDate: 2022-12-04
      DOI: 10.31661/gmj.v11i.2165
      Issue No: Vol. 11 (2022)
       
  • Neurological Symptoms in Coronavirus Disease 2019 Patients: An Updated
           Literature Review

    • Authors: Somayeh Mohammadi, Amirabbas Rostami, Fateme Naghdizadeh, Mahdie ShojaeiBaghini, Nooshin Karami, Sohrab Negargar, Mohsen Emadi, Morteza Jafarinia
      Abstract: Several studies have reported that coronavirus disease 2019 (COVID-19) can lead to multi-organ dysfunction. COVID-19 has been linked to a variety of neurological symptoms, according to the literature. The various paths via which the brain can be infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as the symptoms of COVID-19 in neurological diseases, are discussed. COVID-19 symptoms have been observed in neurological illnesses such as epilepsy, ischemic stroke, multiple sclerosis, Alzheimer's disease, subarachnoid hemorrhage, Guillain–Barré syndrome, and Parkinson's disease in several investigations.
      PubDate: 2022-11-23
      DOI: 10.31661/gmj.v11i.2539
      Issue No: Vol. 11 (2022)
       
  • Pneumoscrotum, a Rare Presentation of Barotrauma Following Noninvasive
           Positive Pressure Ventilation in Patients with Severe COVID-19 Pneumonia

    • Authors: Mohsen Shafiepour, Mohammad Javad Najafzadeh, Seyed Mehdi Hashemi Bajgani, Behnam Dalfardi
      Abstract: Background: Patients with Coronavirus disease 2019 (COVID-19) pneumonia are at risk of hypoxemic respiratory failure. Hence, many patients may require noninvasive positive pressure ventilation (NIPPV) during their hospital course. Using mechanical ventilation such as bilevel positive airway pressure or a ventilator to provide NIPPV may result in adverse events, including barotrauma. Case Report: We reported two cases (40- and 43-years-old men) of severe COVID-19 pneumonia and hypoxemic respiratory failure who underwent NIPPV for respiratory support. These cases were complicated with barotrauma in their course of hospital admission that manifested with pneumoscrotum. Conclusion: In the cases of pneumoscrotum, it is crucial to understand its underlying etiology and origin since this clinical finding may be the outcome of life-threatening illnesses requiring urgent treatment.
      PubDate: 2022-11-20
      DOI: 10.31661/gmj.v11i.2372
      Issue No: Vol. 11 (2022)
       
  • Effects of Transfer Energy Capacitive and Resistive On Musculoskeletal
           Pain: A Systematic Review and Meta-Analysis

    • Authors: Babak Vahdatpour, Shila Haghighat, Leyli Sadri, Mehdi Taghian, Soroush Sadri
      Abstract: The use of transfer energy capacitive and resistive (TECAR) therapy to treat musculoskeletal pain has not been clearly established. Hence, this study was conducted to combine the available results. We searched the main databases, including PubMed (January 1950), Web of Knowledge (January 1945), Scopus (January 1980), and ProQuest (January 1983) until December 2021, to find the related studies. Only those studies were included that assessed the pain in participants who received TECAR therapy and compared it with a control group. Using the random effect model, standardized mean difference (SMD) was calculated at a 95% confidence interval (CI). The differences between patients and control group were -1.04 after four weeks of intervention (95% CI: -1.59 to -0.48, I2=86.9%) and -1.80 after eight weeks (95% CI: -2.15 to -1.46, I2=87%), which was significant (P<0.001). The intra-group pain comparison before and after two, four, and eight weeks of TECAR therapy obtained SMD levels of -3.96 (95% CI: -5.28 to -2.65, I2=96.9%), -4.12 (95% CI: -5.98 to -2.26, I2=97.3), and -5.03 (95% CI: -7.23 to -2.83, I2=92.2%), respectively. Despite some limitations, our findings may assist clinicians in decision-making about TECAR therapy for the approach to musculoskeletal pain based on evidence-based medicine.
      PubDate: 2022-11-15
      DOI: 10.31661/gmj.v11i.2407
      Issue No: Vol. 11 (2022)
       
  • Apoptosis Effects of Oxalis Corniculata L. Extract on Human MCF-7 Breast
           Cancer Cell Line

    • Authors: Amir Reza Gholipour, Leila Jafari, Mahsa Ramezanpour, Mehdi Evazalipour, Maral Chavoshi, Fatemeh Yousefbeyk, Saghi Jani Kargar Moghaddam, Mohammad Hossein Yekta Kooshali, Nahid Ramezanpour, Puyan Daei, Saeed Ghasemi, Masoud Hamidi
      Abstract: Background: Recently, the non-toxic properties of natural plant products have gained more focus as anticancer agents. Therefore, this study aimed to assess the apoptosis effects of the ethanolic extract of Oxalis corniculata on the MCF-7 breast cancer cell line. Materials and Methods: In this experimental study, aerial parts of O. corniculata were collected in Lahijan city (Iran), and after confirmation, they were dried and extracted with ethanol for 24 h. Then, the total phenolic and flavonoid contents of the extract were measured. The 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay was used to measure the antioxidant properties of the extract. Selected cell lines (MCF-7 and human dermal fibroblast) were cultured in 6-wells dishes (1×106 cells/well). After 72 h of treating the extract, cytotoxicity was assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. The expression of apoptotic genes (such as p53, bcl-2, bax, and CD95) was studied by real-time polymerase chain reaction (PCR). Results: The extract's total phenolic content was 31.30±02 µg of gallic acid equivalents/mg of dry extract, and the total flavonoid content was 49.61±04 µg of quercetin as equivalents/mg of extract. The antioxidant activity of O. corniculata was measured at the dose of 619.2 µg/µl, indicating that it decreases cancer cell viability and enhances apoptosis. Within the half maximal inhibitory concentrations, real-time PCR revealed substantial increases in p53 (P<0.001), CD95 (P<0.05), and bcl-2 expression (P<0.05) in MCF-7 cells treated with O. corniculata. Conclusion: This study suggests that O. corniculata may cause apoptosis by oxidative stress in cancer cells
      PubDate: 2022-10-31
      DOI: 10.31661/gmj.v11i.2484
      Issue No: Vol. 11 (2022)
       
  • Protective Effect of Hydroalcoholic Extract of Clove on
           Thioacetamide-Induced Hepatotoxicity Animal Model

    • Authors: Manzar Banoo Shojaeifard, Sarah Hojjati, Salman Vojdani, Simin Keshavarz
      Abstract: Background: The drug-induced liver injury (DILI) has a wide range of clinical presentations, from asymptomatic liver enzyme elevations to cirrhosis. Herbal dietary supplements may be beneficial to reduce the risk of hepatotoxicity. This study aimed to evaluate the effects of different doses of clove extracts on humoral factors in rats with hepatotoxicity induced by thioacetamide. Materials and Methods: In this experimental study, rats were divided into nine groups (10 rats per each). The Control group received no treatment. The Sham group was treated with oral administration of distilled water (0.5 ml) for 21 days. The positive control group received thioacetamide (50 mg/kg for three days) intraperitoneally. The clove group was divided into three subgroups and given daily oral administrations of 50, 150, and 300 mg/kg of clove hydroalcoholic extracts (for 21 days). Rats in the experimental group were divided into three subgroups and subjected to 50 mg/kg thioacetamide injection after receiving hydroalcoholic extracts of clove (50, 150, and 300 mg/kg, respectively) for 21 days in the last three days. All rats were sacrificed after 48 hours to measure liver function parameters (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total plasma protein, and albumin). Results: The rats that received thioacetamide showed liver damage by increased serum liver biomarkers and decreased levels of total plasma protein and albumin compared to the control group. The different doses of clove extract resulted in a significant improvement of liver damage by reduced serum liver enzymes levels and increased total plasma protein and albumin. Conclusion: Oral administration of the different doses of the clove extract (50, 150, and 300 mg/kg) for 21 consecutive days could significantly improve the changes associated with serum biomarkers of hepatotoxicity
      PubDate: 2022-10-23
      DOI: 10.31661/gmj.v11i.1603
      Issue No: Vol. 11 (2022)
       
  • Effect of Sodium Butyrate and Epigallocatechin-3-Gallate on the Genes
           Expression of Intrinsic Apoptotic Pathway on PA-TU-8902, CFPAC-1, and
           CAPAN-1 Human Pancreatic Cancer Cell Lines

    • Authors: Masumeh Sanaei, Fraidoon Kavoosi, Iraj Poursadgh Soufiani
      Abstract: Background: Histone deacetylase inhibitors (HDACIs) are novel anticancer agents that induce cell death and cycle arrest. Several studies reported that HDACIs induce apoptosis via two well-defined intrinsic/mitochondrial and death receptor pathways. In addition to HDACIs, DNA methyltransferase inhibitors effectively revert the promoter hypermethylation of tumor suppressor genes and apoptosis induction. The current study aimed to investigate the effect of sodium butyrate and epigallocatechin-3-gallate (EGCG) on the genes expression of the intrinsic pathway (BAX, BAK, APAF1, Bcl-2, and Bcl-xL), p21, and p53 on PA-TU-8902, CFPAC-1, and CAPAN-1 human pancreatic cancer cell lines. Materials and Methods: The PA-TU-8902, CFPAC-1, and CAPAN-1 cells were treated with sodium butyrate and EGCG. To determine cell viability, cell apoptosis, and the relative gene expression level, the 3-(4,4-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, flow cytometry, and real-time quantitative reverse transcription polymerase chain reaction were done, respectively. Results: Both compounds changed the expression levels of the mentioned genes in a p53-dependent and -independent manner, which induced cell apoptosis and inhibited cell growth in all three cell lines. Conclusion: We indicated that sodium butyrate and EGCG could induce apoptosis in human pancreatic cancer cell lines.
      PubDate: 2022-10-18
      DOI: 10.31661/gmj.v11i.2248
      Issue No: Vol. 11 (2022)
       
  • Changes in Serum Alkaline Phosphatase, Calcium, and Parathyroid Hormone
           with Different Doses of Iodine Therapy

    • Authors: Mohammad Mehdi Movahedi, Gholam Reza Karimaghaei, Ahmad Noori, Mohammad Atefi, Tahereh Mahmoudi, Farshid Gheisari
      Abstract: Background: Despite the benefits of radioactive iodine (RAI) therapy as an adjunctive treatment for thyroid cancer, it can be associated with several side effects. The main purpose of this study was to determine the changes in serum alkaline phosphatase (ALP), calcium (Ca), and parathyroid hormone (PTH) at different doses of RAI therapy among patients who were referred to the nuclear medicine department of Namazi Hospital, Shiraz. Materials and Methods: This cross-sectional study was conducted on 60 patients with papillary thyroid cancer who underwent RAI therapy at different doses of 100, 150, and 200 mCi. The ALP, Ca, and PTH levels of patients were measured before and 60 days after RAI therapy. Results: Our study revealed that RAI therapy at all doses significantly increased ALP level in comparison with baseline amounts (P≤0.05). However, changes in PTH and Ca levels were not significant among patients who received different doses of RAI (P˃0.05). Conclusion: RAI therapy could affect important hormones and enzymes such as ALP and PTH. This issue can be considered in diagnostic and therapeutic prescriptions of RAI for the treatment of thyroid cancer.
      PubDate: 2022-10-18
      DOI: 10.31661/gmj.v11i.2397
      Issue No: Vol. 11 (2022)
       
  • Neuropharmaceutical Properties of Naringin Against Alzheimer's and
           Parkinson's Diseases

    • Authors: Maryam Poudineh, Tahere Ghotbi, Farnoush Azizi, Nooshin Karami, Zahra Zolfaghari , Farshid Gheisari, Mohammad Hormozi, Sahar Poudineh
      Abstract: Neurological complications are considered the leading cause of disability and the second cause of death worldwide. Although the most common neurological disorders affecting a large population are Alzheimer's (AD) and Parkinson's diseases (PD), no definitive treatment has been propounded in the clinic. As in recent years, special attention has been paid to medicinal herbal products as one of the ways to meet the challenges of treating diseases. This review study aimed to introduce the naringin neuroprotective effects as an abundant flavonoid in grapes and citrus fruits on the most common neurological disorders, including AD and PD. For this purpose, the specified keywords were searched in PubMed, Web of Science, Scopus, Embase, and Google Scholar, and the results were entered into the study after a concise overview. The findings show naringin can confront neurological disorders through several mechanisms such as modulating stress response pathways, preventing apoptosis, oxidative stress, and neuroinflammation, excessive chelating amounts of metal ions, thereby improving cognitive impairment and memory loss induced by neurological disorders. However, further studies, particularly on human, are critical for the final confirmation of obtained findings.
      PubDate: 2022-08-20
      DOI: 10.31661/gmj.v11i.2337
      Issue No: Vol. 11 (2022)
       
  • How Can Clinical Communication Skills Improve Patient-Physician
           Relationship Building'

    • Authors: Afshin Borhani-Haghighi
      PubDate: 2022-08-16
      DOI: 10.31661/gmj.v11i.2480
      Issue No: Vol. 11 (2022)
       
  • Effects of Parathyroidectomy on Patients’ Neuropsychological
           Condition

    • Authors: Zahra Hoseini Tavassol, Mahnaz Pejman Sani, Shirin Hasani-Ranjbar, Bagher Larijani
      PubDate: 2022-08-04
      DOI: 10.31661/gmj.v11i.2366
      Issue No: Vol. 11 (2022)
       
  • The Role of 4G allele in Plasminogen Activator Inhibitor type-1 rs1799889
           Gene as Biomarker to Thrombophilic Complication among Type 2 Diabetic
           Patients

    • Authors: Rowida Eljack Ibrahim, Khalid Abdelsamea Mohamedahmed
      PubDate: 2022-08-03
      DOI: 10.31661/gmj.v11i.2447
      Issue No: Vol. 11 (2022)
       
  • Comparative Efficacy of Low-Level Laser Acupuncture and Cupping for
           Treatment of Patients with Myofascial Pain Dysfunction Syndrome: A
           Double-blinded, Randomized Clinical Trial

    • Authors: Seyed Masoud Sajedi, Farid Abbasi, Mohammad Asnaashari, Ali Akbar Jafarian
      Abstract: Background: Myofascial pain dysfunction syndrome (MPDS) is among the most common causes of facial pain. This study compared the efficacy of low-level laser (LLL) acupuncture and cupping for the treatment of MPDS. Materials and Methods: This double-blind, before-after, randomized clinical trial evaluated 60 MPDS patients that were divided into two groups for LLL acupuncture (808 nm, 0.5 W, 30 J, 4 J/cm2 energy density, 60 seconds; group 1), and cupping (group 2) of masticatory muscle trigger points. Both treatments were performed for maximally eight sessions once every other day. The level of pain at the trigger points was measured upon admission, before and 5 minutes after treatment in each session, at ten days, and two months after treatment completion by a visual analog scale (VAS). The painless maximum mouth opening (MMO) and patient satisfaction with treatment were also assessed at the time as mentioned earlier points. Results: Averagely, 4.5 treatment sessions were required to achieve a 50% reduction in VAS pain score, with no significant difference between the two groups (P=0.9). Both treatments significantly decreased the number of trigger points and pain score, but this reduction occurred significantly sooner in the cupping group (P<0.01). MMO significantly improved in both groups after treatment with no significant difference between them (P=0.2). Patients were significantly more satisfied with LLL acupuncture (P<0.05). Conclusion: Both cupping and LLL acupuncture are equally effective for MPDS; thus, the patient can choose the type of treatment after receiving sufficient information regarding the two modalities. [GMJ.2022;11:e2305]
      PubDate: 2022-06-11
      DOI: 10.31661/gmj.v11i.2305
      Issue No: Vol. 11 (2022)
       
  • Effects of Dimethyl Fumarate on the Karnofsky Performance Status and Serum
           S100β Level in Newly Glioblastoma Patients: A Randomized, Phase-II,
           Placebo, Triple Blinded, Controlled Trial

    • Authors: Milad Shafizadeh, Ehsan Jangholi, Seyed Farzad Maroufi, Mohsen Rostami, Ahmad Bereimipour, Shahram Majidi, Niayesh Mohebbi, Alireza Khoshnevisan
      Abstract: Background: Glioblastoma (GBM) is the most common primary central nervous system
      malignancy with a low survival without extra logistics. Currently, there is no definitive
      chemotherapy among the studied options. This study aims to evaluate the neuroprotective
      effects of dimethyl fumarate (DMF) on surgical brain injuries in patients treated for GBM.
      Materials and Methods: This randomized, phase II, placebo, triple-blinded, controlled trial
      was performed on 36 patients with a diagnosis of GBM. All the patients received DMF (240
      mg, three-times per day) or placebo (with the same shape and administration route) one week
      before surgery. Also, patients in both groups after the operation received standard treatments
      (radiotherapy plus chemotherapy). In addition, Kanofsky's performance status (KPS) score was
      evaluated at baseline and one month later. Also, serum S100β was measured 48 hours before
      and after surgery. Results: There was no significant difference among DMF and control groups
      with regard to age, gender, and the extent of resections (P˃0.05). The most adverse event in
      both groups was a headache. Although the serum S100β level was not markedly changed after
      surgery, the mean KPS in the DMF group was higher than in the control group after surgery.
      Conclusion: The DMF could be a possible good regime for the treatment of GBM; however,
      questions are raised regarding its efficacy and application for the addition to standard treatment.
      [GMJ.2022;11:e1897]
      PubDate: 2022-05-31
      DOI: 10.31661/gmj.v11i.1897
      Issue No: Vol. 11 (2022)
       
  • Treadmill Exercise Improves Stereotypical Behaviors in Autistic Rats

    • Authors: Vahide Alipour, Ramin Shabani, Mohammad-Reza Zarrindast, Farhad Rahmani-Nia, Mohammad Nasehi
      Abstract: Background: Autism spectrum disorder (ASD) is identified by developmental deficits that lead to repetitive/stereotypic patterns of behavior and impaired social interactions. Studies have been indicated that exercise can decrease stereotypic behaviors in animal models of ASD. This research was designed to discover the effects of different models of forced exercise on stereotypical behaviors in a rat model of ASD induced by thimerosal (THIM). Materials and Methods: Fifty-six male Wistar rats were divided into eight groups. The rats were received saline (1 ml/kg) or THIM (300 μg Hg/kg) by four intramuscular injections on 7, 9, 11, and 15 postnatal days. The rats were also treated by several protocols of treadmill exercise, including non-sedentary, sedentary, protocol 1, protocol 2, and a combination of protocols 1 and 2. Results: Our study showed that THIM decreased the grooming time compared to the control group. Moreover, protocol 2 exercise significantly decreased grooming time in stranger zone 2 compared to the THIM group. Conclusions: Our results showed that stereotypical behaviors exaggerated by THIM and moderate exercise could improve ASD-associated behaviors in the THIM-treated rats. Hence, moderate exercise may be a useful protocol for the treatment of ASD. [GMJ.2022;11:e1990]
      PubDate: 2022-05-09
      DOI: 10.31661/gmj.v11i.1990
      Issue No: Vol. 11 (2022)
       
  • Protective Effects of Coenzyme Q10 Along with Fe2O3 Nanoparticles On Sperm
           Parameters in Rats with Scrotal Hyperthermia

    • Authors: Mahshid Deldar Abad Paskeh, Nahid Babaei, Maliheh Entezari, Mehrdad Hashemi, Abbas Doosti
      Abstract: Background: One of the most important factors in reducing the birth rate is male infertility, and one of the main reasons for male infertility is scrotal hyperthermia (SH). Therefore, this study aimed to investigate the protective effect of coenzyme Q10 (CoQ10) along with Fe2O3 nanoparticles on semen parameters in rats with SH. Materials and Methods: Forty-eight adult male Wistar rats were divided into eight groups: healthy control, control group receiving Fe2O3 nanoparticles, control group receiving CoQ10, control group receiving Fe2O3 nanoparticles plus CoQ10, SH group, SH group receiving CoQ10, SH group receiving Fe2O3 nanoparticle, and SH group receiving Fe2O3 nanoparticles plus CoQ10. After killing rats, semen was collected from epididymal tissue, and parameters such as sperm viability, motility, concentration, and morphology were studied. Results: SH significantly reduced sperm concentration, motility, and viability, as well as altering sperm morphology in rats. Nevertheless, CoQ10 strongly improved sperm parameters in SH rats. Fe2O3 nanoparticles led to a sharp decrease in sperm parameters; however, during the simultaneous administration of Fe2O3 nanoparticles with CoQ10, improvement in sperm parameters was seen in the SH rats. Conclusion: Our findings suggest that CoQ10, along with Fe2O3 nanoparticles, has a protective effect against spermatogenic cell death induced by SH. Thus, green synthesis of nanoparticles with the administration of antioxidants, including CoQ10 is recommended for the treatment of SH. [GMJ.2022;11:e2046]
      PubDate: 2022-05-08
      DOI: 10.31661/gmj.v11i.2046
      Issue No: Vol. 11 (2022)
       
  • Designing A National Model of Medical Facilities Fair Distribution for
           Iranian Social Security Organization

    • Authors: Ebrahim Naelbafroui, Amir Ashkan Nasiripour, Ali Komeili, Leila Riahi, Kamran Hajinabi
      Abstract: Background: Fair Distribution of Medical Facilities is one of the most critical issues affecting economic and health indicators. Due to the significant role of ISSO in meeting the medical needs and its high coverage (almost 42%) in Iran, we aimed to identify the factors influencing medical facilities' fair distribution in the ISSO. Materials and Methods: This applied study was conducted as a descriptive study in the ISSO in 2018. Variables affecting medical facilities distribution were elicited from the literature review and through an interview with 16 experts who were occupied in the healthcare management field. Then, a Likert scale-based questionnaire with 56 items in 7 sections was developed. Questionnaires were distributed among 456 person received questionnaires, and 415 responded to all questions. All participants were experts in the healthcare section of the ISSO all over the country. Data were analyzed via exploratory and confirmatory factor analysis and structural equations using SPSS 23 and AMOS-24 software. Results: By exploratory and confirmatory factor analysis, seven main factors (demographic factors, geographical factors, functional factors, structural factors, humanistic factors, economic factors, and Contract parties factors) were identified as critical factors affecting medical facilities distribution. Each aspect included many components. AMOS software showed the significance of variables by P-value and critical ratio (CR) indices to analyze the conceptual model of the research. Function factors with standard coefficients of 0.85 had the most, and economic factors with a standard coefficient of 0.53 had a minor effect on the distribution of medical facilities in the ISSO. Conclusion: To have a more efficient medical facilities distribution in the ISSO must consider all identified factors, special attention should be given to the maximum use of available medical facilities. Furthermore, more attention should be paid to distributing human resources, finance, and medical equipment.
      PubDate: 2022-04-24
      DOI: 10.31661/gmj.v11i.2012
      Issue No: Vol. 11 (2022)
       
  • Heme Oxygenase-1 (HMOX1) Gene Polymorphisms as Predictive Markers of
           Increased Risk of Thrombosis among Patients with COVID-19

    • Authors: Mai Shakir Mohammed, Khalid Abdelsamea Mohamedahmed
      PubDate: 2022-04-02
      DOI: 10.31661/gmj.v11i.2398
      Issue No: Vol. 11 (2022)
       
  • Role of Percutaneous Laser Disc Decompression in Patients with Lumbar Disc
           Herniation on Pain Relief: A Quasi-Experimental Pilot Study

    • Authors: Sajjad Saghebdoust, Seyed Ghavam Shafagh, Neda Pak, Reza Fekrazad, Masoud Khadivi, Morteza Faghih Jouibari, Mohammad Reza Boustani
      Abstract: Background: Disc herniation is broadly defined as a localized or focal displacement of disc material beyond the limits of the intervertebral disc space. The disc material may be the nucleus, cartilage, fragmented apophyseal bone, annular tissue, or any combination thereof. Laser surgery is one of the treatment modalities for treating patients with lumbar disc herniation. This study aims to examine the effect of Percutaneous Laser Disc Decompression (PLDD) in patients with lumbar disc herniation. Materials and Methods: This study was conducted on 58 patients who underwent PLDD (optical fiber inserted through an 18G needle, 8 joules, and 8 watts). Individuals were monitored before and after treatment using the comparing visual analog scale (VAS) pain score (from 0 [no pain] to 10 [severe pain]). Results: The mean age of participants was 63.19±13.48 years. Regarding gender, 24 patients (41.4%) were female. The mean VAS score before surgery was 8.73±1.29, and VAS score after surgery was 55.2±2.71, which means pain was significantly reduced (P<0.001). Conclusion: The patients’ post-PLDD pain may decrease; hence, PLDD can use as an appropriate method for treating lumbar disc herniation. [GMJ.2022;11:e2382]
      PubDate: 2022-03-25
      DOI: 10.31661/gmj.v11i.2382
      Issue No: Vol. 11 (2022)
       
  • Effectiveness of Online Versus Telephone Counseling of
           Rational-Emotional-Behavioral Therapy on Sexual Function of Women
           Undergoing Cardiac Rehabilitation: A Randomized Clinical Trial

    • Authors: Tahmineh Farajkhoda , Fatemeh Zahra Memar, Mahdi Khanabadi, Mohammadtaghi Sarebanhassanabadi
      Pages: 2396 - 2396
      Abstract: Background: Sexual function in patients with cardiovascular disease (CVDs) is often associated with anxiety and irrational beliefs. Moreover, 60-78% of patients with CVDs report sexual problems. Some studies suggest that sexual counseling is necessary for these patients but is not usually provided for them. Online or telephone counseling may be helpful during the covid-19 pandemic, but studies on its application to sexual function appear to be limited. This study aimed to investigate the effectiveness of online vs. telephone counseling of rational-emotional-behavioral therapy (REBT) on the sexual function of women undergoing cardiac rehabilitation. Materials and Methods: In this randomized clinical trial study, 46 women diagnosed with CVDs under rehabilitation were assigned into online and telephone groups. Overall, eight 60-min intervention sessions were held (once a week). The Female's Sexual Function Index (FSFI) questionnaire was completed by the women at baseline, week 8th, and follow-up week 12th (main outcome). Results: FSFI scores between the two groups at baseline (online: 13.28±2, telephone: 12.68±1.52, P=0.254) compared to week 12th (online 28.86±2.44, telephone, 26.6±2.10, P=0.002) were significantly different. As for within-group comparison in baseline compared to week 12th statistically significant difference was observed in all subscales of FSFI (P<0.05). Conclusion: Online and telephone REBT counseling can improve the sexual function of women undergoing cardiac rehabilitation, but online counseling appears to be more effective. Thus, this method is recommended to improve the sexual function of these women during the covid-19 pandemic
      PubDate: 2022-09-16
      DOI: 10.31661/gmj.v11i.2396
      Issue No: Vol. 11 (2022)
       
 
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