Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (686 journals)            First | 1 2 3 4     

Showing 601 - 203 of 203 Journals sorted alphabetically
Safety     Open Access   (Followers: 2)
Safety and Health at Work     Open Access   (Followers: 75)
Safety and Reliability     Hybrid Journal   (Followers: 4)
Safety in Extreme Environments     Hybrid Journal  
Safety in Health     Open Access   (Followers: 74)
Saintika Medika     Open Access  
Salud & Sociedad: investigaciones en psicologia de la salud y psicologia social     Open Access  
Salud Areandina     Open Access  
Salud Colectiva     Open Access  
Salud(i)ciencia     Open Access  
Salus     Open Access  
Salute e Società     Full-text available via subscription  
Samsun Sağlık Bilimleri Dergisi     Open Access  
Saúde Coletiva     Open Access  
Saúde e Meio Ambiente : Revista Interdisciplinar     Open Access  
Saúde em Redes     Open Access  
Saúde.com     Open Access  
Scandinavian Journal of Work, Environment & Health     Partially Free   (Followers: 13)
School Mental Health     Hybrid Journal   (Followers: 10)
Scientia Medica     Open Access  
Scire Salutis     Open Access  
Serviço Social e Saúde     Open Access  
Sextant : Revue de recherche interdisciplinaire sur le genre et la sexualité     Open Access  
Sexual Health     Hybrid Journal   (Followers: 5)
Sexual Medicine Reviews     Full-text available via subscription   (Followers: 2)
Sierra Leone Journal of Biomedical Research     Open Access  
Sleep and Vigilance : An International Journal of Basic, Translational and Clinical Research     Hybrid Journal   (Followers: 1)
Sleep Health     Full-text available via subscription   (Followers: 5)
Sleep Science and Practice     Open Access   (Followers: 10)
SMAD, Revista Electronica en Salud Mental, Alcohol y Drogas     Open Access   (Followers: 2)
Smart Health     Hybrid Journal  
Social Determinants of Health     Open Access   (Followers: 2)
Social Theory & Health     Hybrid Journal   (Followers: 3)
Social Work in Health Care     Hybrid Journal   (Followers: 26)
Social Work in Mental Health     Hybrid Journal   (Followers: 16)
Social Work in Public Health     Hybrid Journal   (Followers: 13)
Society, Health & Vulnerability     Open Access   (Followers: 4)
Sosiaalilääketieteellinen Aikakauslehti     Open Access  
South African Family Practice     Open Access   (Followers: 3)
South African Journal of Bioethics and Law     Open Access   (Followers: 1)
South African Journal of Child Health     Open Access   (Followers: 1)
South African Journal of Communication Disorders     Open Access   (Followers: 1)
South East Asia Journal of Public Health     Open Access   (Followers: 3)
South Eastern European Journal of Public Health     Open Access   (Followers: 1)
Southern African Journal of Critical Care     Open Access   (Followers: 4)
Southern African Journal of Public Health     Open Access  
Southwest Respiratory and Critical Care Chronicles     Open Access   (Followers: 1)
Space Safety Magazine     Free   (Followers: 49)
Sri Lanka Journal of Child Health     Open Access  
SSM - Population Health     Open Access   (Followers: 5)
SSM - Qualitative Research in Health     Open Access   (Followers: 2)
Stigma and Health     Full-text available via subscription   (Followers: 2)
Sundhedsprofessionelle studier     Open Access  
Sustainable Earth     Open Access   (Followers: 2)
Sustinere : Revista de Saúde e Educação     Open Access  
System Safety : Human - Technical Facility - Environment     Open Access   (Followers: 3)
Systematic Reviews     Open Access   (Followers: 14)
Tanzania Journal of Health Research     Open Access   (Followers: 2)
Technology and Innovation     Full-text available via subscription   (Followers: 2)
Tempus Actas de Saúde Coletiva     Open Access  
Textos & Contextos (Porto Alegre)     Open Access  
The Journal of Aquatic Physical Therapy     Full-text available via subscription   (Followers: 4)
The Journal of Rural Health     Hybrid Journal   (Followers: 5)
The Lancet Child & Adolescent Health     Hybrid Journal   (Followers: 10)
The Lancet Global Health     Open Access   (Followers: 74)
The Lancet Planetary Health     Open Access   (Followers: 5)
The Lancet Regional Health : Americas     Open Access  
The Lancet Regional Health : Europe     Open Access   (Followers: 3)
The Lancet Regional Health : Southeast Asia     Open Access   (Followers: 8)
The Lancet Regional Health : Western Pacific     Open Access   (Followers: 2)
The Meducator     Open Access   (Followers: 1)
Theoretical Issues in Ergonomics Science     Hybrid Journal   (Followers: 9)
Therapeutic Communities : The International Journal of Therapeutic Communities     Hybrid Journal   (Followers: 17)
Tidsskrift for Forskning i Sygdom og Samfund     Open Access  
Tidsskrift for psykisk helsearbeid     Full-text available via subscription  
Tobacco Control     Hybrid Journal   (Followers: 16)
Tobacco Control and Public Health in Eastern Europe     Open Access   (Followers: 3)
Transgender Health     Open Access   (Followers: 4)
Transportation Safety and Environment     Open Access   (Followers: 1)
Tropical Journal of Health Sciences     Full-text available via subscription  
Tropical Medicine and Health     Open Access   (Followers: 2)
TÜBAV Bilim Dergisi     Open Access  
Universal Journal of Public Health     Open Access  
Universidad y Salud     Open Access  
Unnes Journal of Public Health     Open Access  
Value in Health Regional Issues     Hybrid Journal  
Vascular Health and Risk Management     Open Access   (Followers: 2)
Vigilância Sanitária em Debate     Open Access  
Violence and Gender     Full-text available via subscription   (Followers: 22)
Water Quality, Exposure and Health     Hybrid Journal   (Followers: 2)
Western Pacific Surveillance and Response     Open Access  
Women & Health     Hybrid Journal   (Followers: 10)
World Health & Population     Full-text available via subscription   (Followers: 3)
World Medical & Health Policy     Hybrid Journal   (Followers: 2)
Zeitschrift für Arbeitswissenschaft     Hybrid Journal  
Zoonotic Diseases     Open Access   (Followers: 24)
Електромагнітна сумісність та безпека на залізничному транспорті     Open Access  
مجله بهداشت و توسعه     Open Access  

  First | 1 2 3 4     

Similar Journals
Journal Cover
Water Quality, Exposure and Health
Number of Followers: 2  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1876-1666 - ISSN (Online) 1876-1658
Published by Springer-Verlag Homepage  [2468 journals]
  • Metal (loid) Exposure and Overweight and Obesity in 6–12-Year-Old
           Spanish Children

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      Abstract: Abstract Epidemiological studies focusing on metal(oid) exposure and excess body weight among children show inconsistent results and the influence of metal(loid) mixtures has been little studied. We aimed to explore the effect of 10 metal(loid)s, individually and in combinations, on overweight and obesity among children aged 6–12. Urinary levels of these metal(oid)s from 92 controls and 51 cases with overweight and obesity were analyzed. Metal(loid) levels were log-transformed and categorized into tertiles according to the control group cutoff points. Two logistic regression models and weighted quantile sum regressions (WQS) were run: model 1 adjusting for age, sex, creatinine, energy intake and physical activity and model 2 additionally adjusting for maternal education, rice and fish consumption. In the single metal(oid) exposure model, there was a trend of significant negative association for urinary cobalt (Co), where children in the third tertile had lower odds of present overweight and obesity than those in the first (Odds Ratio, OR = 0.43; 95% Confidence Interval, CI = 0.20–0.93). Urinary chromium (Cr) levels were borderline-significant negatively associated with overweight and obesity (ORa = 1.70; 95% CI = 0.97–2.98). Molybdemun, Cr and Co had a major contribution to the inverse association between metal(loid) mixture and overweight and obesity as well as lead, cadmium and total arsenic in the positive relationship. Our findings in this explorative study suggested an inverse association of high urinary Co levels with overweight and obesity. Moreover, metal(loid) mixture exposure may have influence on overweight and obesity with an important contribution of Co in the potential negative effect.
      PubDate: 2024-04-05
       
  • Correction: Potential Factors Associated with the Blood Metal
           Concentrations of Reproductive-Age Women in Taiwan

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      PubDate: 2024-04-01
       
  • Fertilization Enhances Grain Inorganic Arsenic Assimilation in Rice

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      Abstract: Abstract To investigate how soil fertilization/amendments alters arsenic speciation grain off-take in paddy rice, rice was grown to maturity in growth chambers fertilized with standard mineral fertilizer, wood ash (rich in silica), pig slurry (rich in organic matter), and non-amended control. The soil was sourced from a Chinese paddy field. The primary fertilized elements (nitrogen, phosphorus, potassium) were kept constant across treatments. Porewater chemistry and soil microbiology were monitored throughout the experiments. Total grain arsenic, sum of inorganic arsenic and dimethylarsinic acid (DMA), was significantly different between treatments (P = 0.024), with inorganic arsenic varying from 0.025 to 0.08 mg/kg and DMA from 0.08 to 0.16 mg/kg for control compared to fertilized, respectively. Fertilizer source made no difference to arsenic speciation concentration in grain. Porewater analysis found that as anaerobism set in, inorganic arsenic, phosphorus and manganese greatly lowered in concentration. Methylated arsenic species concentrations increased over time, concurrent with an increase in pH, decrease in Eh, and increase in total organic carbon and iron, with no strong treatment effects, except for pig slurry that enhanced pH and decreased Eh. Methanogenic archaea, sulfate-reducing bacteria and Acidobacteria increased with time and some Actinobacteria and Firmicutes increased due to slurry, but then decreased with time (P < 0.01). Methanogenic archaea and sulphate-reducing bacteria correlated positively with porewater DMA and negatively with porewater inorganic arsenic (P < 0.05). Genera within the Actinobacteria and Burkholderiaceae correlated negatively with DMA, while genera with iron-reducing capacity (Clostridiales) correlated positively with porewater inorganic arsenic and DMA (P < 0.05).
      PubDate: 2024-04-01
       
  • The Association of Bisphenol A and Parabens Exposure and Oxidative Stress
           in Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

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      Abstract: Abstract Bisphenol A (BPA) and personal care products containing parabens have been linked to disruption of endocrine function. General exposure to BPA and parabens comes from drinking water and food due to the overuse of plastic containers and personal care products. In this study, we sought to determine the relationship between exposure to BPA and parabens with attention-deficit hyperactivity disorder (ADHD) and oxidative stress and the mediating role of oxidative stress in ADHD. This case–control study enrolled 92 children with ADHD and 137 control subjects. Urinary BPA and four paraben levels were measured in these children by ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Oxidative stress biomarkers in urine were analyzed by high-performance liquid chromatography-electrospray-ionization-mass spectrometry. The results showed that there were significantly higher concentrations of methyl paraben (MP) and ethyl paraben (EP) for ADHD children than in the control group (MP: 35.76 vs. 26.73 µg/g cre., p-value = 0.05; EP: 2.17 vs. 1.41 µg/g cre., p-value = 0.01). It was found that children with increased EP concentration have a higher risk of ADHD (odds ratio [OR]: 2.58, 95% CI 1.42–4.72), and the risk, in particular, increases in male children (OR: 2.83, 95% CI 1.37–5.84). No significant mediating effect of oxidative stress from BPA or parabens exposure on ADHD was found. The results suggest the role of parabens exposure in the onset of childhood ADHD, particularly the increased risk in male children.
      PubDate: 2024-04-01
       
  • Toxic Effects of Atrazine on Liver and Underlying Mechanism: A Review

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      Abstract: Abstract Atrazine (ATR) is one kind of herbicide, which is widely used for weeding of dry crops such as corn, sorghum, and fruit trees. Due to its long half-life in soil and refractory degradation in water, it is easy to cause continuous pollution to the environment. ATR can enter the human body through drinking water, diet, etc., causing damage to multiple organs. The liver is the main target organ for ATR metabolism and toxicity. Studies have found that ATR can accumulate in the liver, and a wide variety of adverse health effects have been seen in studies across multiple models, exposure times, and exposure periods. Research has shown that ATR can accumulate in the liver, and continuous ATR exposure causes liver swelling and hepatocyte damage. ATR can cause oxidative stress and damage the liver, affecting apoptosis and autophagy. ATR exposure may cause change in gene expression in hepatocyte function. The existing research on liver damage caused by ATR exposure is based on toxicological experimental summaries, lacking a systematic review from in vivo to in vitro and from macro to micro-perspectives.
      PubDate: 2024-04-01
       
  • A Simultaneous Determination of Benzophenone and Camphor UV-Filters,
           Together with Metabolites of Polycyclic Aromatic Hydrocarbons, in Human
           Urine

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      Abstract: Abstract By monitoring biomarkers in urine, personal exposure to selected chemical substances can be assessed. In this paper, we describe the monitoring of 7 benzophenone and 2 camphor UV-filters and 11 metabolites of polycyclic aromatic hydrocarbons (OH-PAHs) in 454 urine samples collected from mothers and new-borns from an industrial (Karvina) and reference area (Ceske Budejovice) over winter and summer seasons. The analytical method consisted of enzymatic hydrolysis, liquid–liquid extraction (ethyl acetate), purification by dispersive solid-phase extraction (Z-Sep sorbent) and ultra-high performance liquid chromatography coupled with tandem mass spectrometry. Benzophenone-1 (BP-1), naphthalen-2-ol (2-OH-NAP), fluoren-2-ol (2-OH-FLUO) and phenanthren-2-ol (2-OH-PHEN) were determined in all urine samples analysed. Benzophenone-3 (BP-3) and 2-OH-NAP were found at the highest concentrations (medians of 5.95- and 5.77-µg/g creatinine). Analytes 3-(4-methylbenzylidene)camphor (3-MBC), 3-benzylidenecamphor (3-BC), chrysen-6-ol (6-OH-CHRY) and benzo(a)pyrene-3-ol (3-OH-BaP) were not detected in any urine sample. Median concentrations of UV-filters and OH-PAHs were compared across regions in the Czech Republic and between mothers and their new-borns from different countries. The median concentrations of UV-filters measured in urine samples from new-borns in our study were similar to samples collected from Brazilian children and the concentrations of these compounds in mothers’ samples were comparable with the concentrations in Danish mothers. In the case of OH-PAHs, the median concentrations of these substances measured in urine samples from Czech new-borns were comparable to median concentrations of these compounds measured in new-born urine from our previous study, and the concentrations in urine collected from Czech mothers were comparable to those reported in Spanish women.
      PubDate: 2024-04-01
       
  • Analysis of Human Co-exposure to Lead and Cadmium Using Human
           Biomonitoring (HBM) Data in a Bayesian Copula-Based Regression Framework

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      Abstract: The identification of human co-exposure to industrial chemicals or environmental substances is of high interest in human health risk assessment. Due to their ubiquity and persistence in the environment, heavy metals such as cadmium (Cd) and lead (Pb) are of particular concern. Approaches to adequately investigating combinations of these and other often highly correlated variables are lacking. This study proposes a modeling approach to investigate the co-exposure to Cd and Pb, and better understanding the variations of blood Cd and Pb (CdB and PbB, respectively) together with potentially determinant factors. A copula-based regression model was built, using Bayesian inference and Markov Chain Monte Carlo simulation, to relate CdB and PbB of 3- to 14-year-old children participating in the German Environmental Survey for Children (GerES IV) with socio-demographic and ancillary exposure-relevant information. A minor to negligible dependence between CdB and PbB was observed, suggesting that Cd and Pb are subject to differing exposure sources/pathways or kinetics within human body. Despite the resulting low association between CdB and PbB, the developed approach provides methodological bases for enhancing the assessment of the cumulative exposure to multiple substances and for deepening the understanding of the determinants of these exposures. Graphical
      PubDate: 2024-04-01
       
  • Temporal and Spatial Evolution of Groundwater Natural Background Levels in
           a Rapid Urbanization Area, Northeast of Beijing, China

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      Abstract: Abstract Understanding the groundwater natural background levels (NBLs) is important in distinguishing groundwater contamination and guiding the groundwater management. Groundwater environment in suburb areas around the large city may suffer from strong impact of human activity during rapid urbanization which will have significant effect on the groundwater natural background levels. Although many previous studies have proposed different methods to understand the spatial distribution of NBLs, its temporal evolution and the relationship with groundwater quality is not well understood. In this study, we investigated the long-term evolution of NBLs and groundwater hydrochemical anomalies in the 59 wells of the Pinggu basin by combining the comprehensive groundwater hydrochemical anomalies identification and groundwater quality assessment. NO3−, Cl−, and SO42− were found to be as the major chemical constitutions demonstrating the strong anomaly degree, which decreased over time. The zoning and evolution of groundwater quality also aligned with the variation of anomaly areas. Regions with a higher degree of abnormality were consistent with those with poorer groundwater quality. The impact of human activities on the groundwater environment decreased in the Pinggu basin compared to the initial years due to the efforts of environment protection and governance by the local government. Investigating the temporal and spatial variation, hydrochemical properties by combination of NBLs and groundwater quality assessment provided a useful approach to understand groundwater environment in rapidly urbanizing areas.
      PubDate: 2024-04-01
       
  • Increased Intestinal Permeability: An Avenue for the Development of
           Autoimmune Disease'

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      Abstract: Abstract The intestinal epithelium acts as the first line of defence against pathogens present in the lumen of the gastrointestinal tract. The epithelium is composed of a single monolayer that includes a variety of cell types, each of which play roles in nutrient and water absorption, antimicrobial defence, and immunomodulation to maintain a homeostatic gut environment. Tight junction (TJ) complexes between adjacent intestinal epithelial cells are responsible for the structural integrity of the gut barrier and controlling the paracellular translocation of luminal contents. The effectiveness of TJs can be impacted by both genetic and environmental factors including microbiota dysbiosis and dietary components. The increased systemic entry of luminal contents has been associated with the development, progression, and/or relapse of autoimmune diseases such as Crohn’s and rheumatoid arthritis. In particular, the extraintestinal spread of luminal microbes possessing components with structural similarity to those of the human host are thought to be involved in the breakdown of immune tolerance towards host components. Here, the structure and function of the intestinal epithelium are discussed as well as the genetic and environmental factors that influence its permeability. There is emphasis on the role of increased intestinal permeability and how the subsequent translocation of luminal contents could be involved in the development and/or exacerbation of autoimmune diseases. This review reinforces how protecting the integrity of the intestinal epithelium and minimising immunological exposure to luminal components, either directly or indirectly, could be a useful strategy in reducing the prevalence and severity of autoimmune diseases.
      PubDate: 2024-04-01
       
  • Infant Exposure and Risk Assessment of Organophosphorus Flame Retardants
           in Human Breast Milk from The Southeast City, China

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      Abstract: Abstract Numerous epidemiological studies have investigated the endocrine disruption of Organophosphorus Flame Retardants (OPFRs) and the potential mechanisms of toxicity. However, in the southeastern region of China, where OPFRs are produced in large amounts, information about the occurrence of OPFRs in breast milk and their potential health risks to infants is still not well known. Herein, we analyzed the levels of OPFRs in 105 breast milk samples collected from Hangzhou, Zhejiang Province by using UPLC-MS/MS and explored the association between maternal population characteristics and the levels of OPFRs. At least two OPFRs were detected in breast milk, and 62% of samples were detected with more than five OPFRs, with the highest detection rate for tris(2-butoxy ethyl) phosphate (TBEP) (96%). The sum concentrations of 9 OPFRs in human milk ranged from 0.44 to 9.61 ng/mL with a mean value of 2.80 ng/mL. TBEP, Triphenyl phosphate (TPHP), and tributyl phosphate (TBP) were the three dominant OPFRs found in breast milk with average concentrations at 0.40, 0.69, and 0.66 ng/mL, respectively. The association between OPFRs and the age of mothers was positively significant, but no significant difference was found between residual concentrations of OPFRs and maternal body mass index (BMI). The noncarcinogenic and carcinogenic risks of OPFR exposure to infants via breast milk are negligible. The data here clarified the occurrence and potential risk of OPFRs in human breast milk, and also reveal that the ingestion of OPFRs through breast milk may be the main route for infants.
      PubDate: 2024-04-01
       
  • Geochemical Investigation of OCPs in the Rivers Along with Drains and
           Groundwater Sources of Eastern Punjab, Pakistan

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      Abstract: Abstract Organochlorine pesticides (OCPs) in surface and groundwater are an environmental problem with substantial human health risk reports in many developing countries, including Pakistan. OCPs are known for their long life, harmful effects, and slow decomposition. Therefore, this study aimed to investigate the water quality of River-Ravi and Sutlej concerning (OCPs) along with main drains and groundwater sources. The total OCPs ranged from 2.1 to 3120.4 (386.9 ± 806.3) µg/L, with the most prevalent compounds being o,p'-DDD, o,p'-DDE. Principal component analysis (PCA) results reveal that agricultural and industrial activities are the primary cause of OCPs pollution in surface and groundwater. Cancer risk of every pollutant in the groundwater was observed in the order of p,p'-DDE > dieldrin > heptachlor > p,p′-DDD > p,p′-DDT; the presence of p,p′-DDE, dieldrin, and heptachlor mostly in aquifer showed that these three OCPs are the most frequent cancer-causing chemicals. The concentrations of OCPs in surface and groundwater were compared with the standard of the United States Environmental Protection Agency (US-EPA). It is found that the concentrations of heptachlor, endrin, dieldrin, HCB, aldrin, mirex, α-BHC, β-BHC, γ-BHC7, δ-BHC, trans-chlordane, cis-chlordane, as well as DDTs (isomers and metabolites) in all water samples were beyond standard water quality guidelines. Ecotoxicological assessments following established water quality guidelines (WQGs) show that OCPs compounds provide a significant threat to the aquatic environment in the study area.
      PubDate: 2024-04-01
       
  • Assessment Between Follicular Fluid Multiple Element Concentrations and
           Hormonal Profiles of Women with Polycystic Ovary Syndrome

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      Abstract: Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged women. Follicular fluid quality affects early embryonic development and multiple stages of pregnancy. This study measured 12 elements in follicular fluid and 5 blood hormones, aiming to identify the associations between multielement concentrations, as well as blood hormone levels, and PCOS to investigate the interference of multielement coexposure on PCOS and examine the potential roles of hormones. Eight elements (As, Cu, Se, Sr, V, Zn, Cr, Ca), but not Mg, showed a positive dose–effect relationship with PCOS. The OPLS models of follicle-stimulating hormone (FSH) and anti-Müllerian hormone (AMH) with relevant elements showed that Mg, Zn, Fe, Se, and V had a more significant effect on FSH and that As, Se, V, Cu, and Zn were positively correlated with AMH (VIP > 1). Further analysis indicated a synergistic effect for FSH and Mg, both of which were protective factors against PCOS; the associations between the five elements and PCOS incidence were mediated by AMH. Changes in hormone levels between multielement coexposure and PCOS development suggest that FSH and Mg are protective against PCOS; female exposure to As, Se, V, Cu, and Zn may affect PCOS progression by perturbing AMH levels.
      PubDate: 2024-04-01
       
  • A Systems Biology Approach Reveals the Endocrine Disrupting Potential of
           Aflatoxin B1

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      Abstract: Background Aflatoxin B1 (AFB1) a mycotoxin produced by Aspergillus flavus and A. parasiticus is a potent carcinogen and causative agent of hepatocellular carcinoma (HCC). It is a food contaminant which presents a major risk to human health. AFB1 contamination poses a significant economic burden, as 25% of the world's food crops need to be destroyed annually. The mechanism of action (MOA) of aflatoxins remains to be fully elucidated. Recent findings suggest that AFB1 mediated endocrine disruption may occur in the population of regions with high contamination, even without evidence of direct dietary intake. Objective An integrative systems biology approach was undertaken to decipher the estrogenic component of the mechanism of action (MOA) of AFB1. Methods Molecular Docking and Molecular dynamics simulations were performed to examine the binding affinity of AFB1 and its metabolite aflatoxin Q1 (AFQ1) with the Estrogen Receptors (ERs). Differential gene expression (DGE), gene ontology (GO) and pathway analyses were carried out on hepatic transcriptomic data generated from in vivo AFB1 exposures. In parallel exposures to the synthetic estrogen ethinylestradiol (EE2) were examined for overlapping effects. Finally, protein–protein interaction (PPI) network analysis assessed the involvement of estrogen responsive targets (ERTs) associated with aflatoxin exposure. Results The free energies of binding affinity and estimated equilibrium dissociation constants (KD) demonstrated that AFB1 and AFQ1 can interact with the ERα and ERβ. DGE and GO analyses highlighted overlap in the responses between AFB1 and EE2 treatments with the activation of key processes involved in estrogenic signaling. PPI network analyses after AFBI exposure revealed a dynamic response to AFB1 treatments with the solid involvement of ERTs in regulatory networks. Conclusions This study revealed molecular interactions between aflatoxins (AFB1, AFQ1) and ERs in addition to overlap in differentially expressed genes and biological processes following AFB1 and EE2 exposures. The estrogenic components at the core of the PPI networks suggest that ER-mediated signaling pathways are a major component in the MOA of aflatoxins.
      PubDate: 2024-04-01
       
  • In Utero Exposure to Lead is Associated with Neural Tube Defects via
           Disturbing the Expression of Endocannabinoid Retrograde Signaling-Related
           Genes

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      Abstract: Abstract Neural tube defects (NTDs) are a group of severe congenital malformations of the central nervous system, for which environmental causes are not fully known. In a human case–control study, we compared lead (Pb) levels in umbilical cord blood serum from 40 NTD cases and 119 controls. In a toxicology study, we treated Institute of Cancer Research (ICR) mice with different dosage of Pb acetate orally from gestational day (GD) 6.5 through 9.5. At GD10.5, mouse embryos were harvested and examined. RNA-sequencing was conducted on the embryos to detect mRNA profiles. siRNAs were used to pull down target genes in human embryonic stem cells to examine the effects of the aberrant gene expression on neural cells. A higher Pb concentration in cord serum was associated with the odds of NTDs [odds ratio (OR): 4.66 (1.69–15.24)]. Lead acetate induced NTDs in 10.6% of mouse fetuses. RNA expression profiles of Pb-induced NTD mice were different from control embryos, especially in endocannabinoid retrograde signaling genes Plcb2, Nfix, and Gabrg2. Down-regulation of Plcb2 and Nfix influenced neural cell differentiation and impaired the formation of neural rosette-like structures. Together, in utero-Pb exposure is associated with development of NTDs via regulating the expression of endocannabinoid retrograde-signaling genes.
      PubDate: 2024-04-01
       
  • Occurrence, Species, and Health Effects of Groundwater Arsenic in Typical
           Rural Areas Along the Northern Foot of the Qinling Mountains, China

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      Abstract: Abstract This research focused on the major water quality parameters and trace elements in 73 groundwater samples collected from some rural areas at the northern foot of Qinling Mountains, and the hydrochemical characteristics of groundwater in this area were investigated. The distribution and enrichment of arsenic (As) in groundwater were specifically explored, the different chemical species of arsenic were calculated using PHREEQC, and the carcinogenic and non-carcinogenic health risks caused by total arsenic were assessed using probabilistic models. The results showed that the concentration of arsenic in groundwater ranged within 1.46–8.69 μg/L, which is close to the World Health Organization's guideline value recommended for drinking water (10 μg/L). The chemical species of arsenic simulated using the PHREEQC model showed that the main species of arsenic in most groundwater samples in the study area were HAsO42− and H2AsO4−, while the main species of arsenic in a few samples were H3AsO3, followed by H3AsO4, AsO43−, AsO33−, HAsO32−, and H4AsO3+, which were present in a relatively small proportion. Changes in environmental acidity and redox conditions had significant effects on the species of arsenic present in groundwater. The results of the health risk assessment showed that the non-carcinogenic risk of human health due to exposure to arsenic is 3.19 × 10–5 and 1.11 × 10–4 for adults and children, respectively. Children are at greater health risk than adults.
      PubDate: 2024-04-01
       
  • Hydrogeochemical Processes Regulating the Groundwater Geochemistry and
           Human Health Risk of Groundwater in the Rural Areas of the Wei River
           Basin, China

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      Abstract: Abstract The hydrochemical characteristics of phreatic water were evaluated in this study, and the hydrogeochemical processes occurring along groundwater flow paths were analyzed using inverse hydrogeochemical simulations. The spatial distributions of groundwater Fe and Mn contents in the study area, their influencing factors, and their correlative probabilistic human health risks were assessed. The results showed that the order of cation content in phreatic water was Ca2+ > Mg2+ > Na+ > K+ and Ca2+ > Na+ > Mg2+ > K+ in the pluvial-alluvial fan and alluvial plain, respectively. Approximately 92.73% of the phreatic water samples were HCO3-Ca·Mg-type water, and only a few belonged to SO4·Cl-Ca·Mg-type water. Twelve percent and forty percent of the phreatic water in the pluvial-alluvial fan and alluvial plain, respectively, showed Fe and Mn concentrations exceeding China's drinking water standards. Hydrogeochemical simulations using PHREEQC showed some differences in water‒rock interactions between paths and along the same path due to differences in lithological and hydrological conditions. In addition, higher Fe and Mn contents mainly occurred in the Huyi District, as well as in some parts of the alluvial plain aquifer. Moreover, groundwater Fe and Mn contents were mainly influenced by redox potential, infiltration of sewage containing high Fe and Mn concentrations, TDS contents, and groundwater flow rates. In the Wei River basin, the probability of the health risk due to NO3-N, Fe, and Mn was ordered as NO3-N > Mn > Fe. The health risks of NO3-N were 3.1% and 18.3% for adults and children, respectively, and the health risks due to Mn were 2.3% and 4.9% for adults and children, respectively. In contrast, the probability of health risk of Fe was negligible.
      PubDate: 2024-04-01
       
  • Environmental Nickel Exposure and Cardiovascular Disease in a Nationally
           Representative Sample of U.S. Adults

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      Abstract: Background Laboratory studies have linked nickel with the pathogenesis of cardiovascular disease (CVD); however, few observational studies in humans have confirmed this association. Objective This study aimed to use urinary nickel concentrations, as a biomarker of environmental nickel exposure, to evaluate the cross-sectional association between nickel exposure and CVD in a nationally representative sample of U.S. adults. Methods Data from a nationally representative sample (n = 2702) in the National Health and Nutrition Examination Survey 2017–20 were used. CVD (n = 326) was defined as self-reported physicians’ diagnoses of coronary heart disease, angina, heart attack, or stroke. Urinary nickel concentrations were determined by inductively coupled plasma mass spectrometry. Logistic regression with sample weights was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of CVD. Results Urinary nickel concentrations were higher in individuals with CVD (weighted median 1.34 μg/L) compared to those without CVD (1.08 μg/L). After adjustment for demographic, socioeconomic, lifestyle, and other risk factors for CVD, the ORs (95% CIs) for CVD compared with the lowest quartile of urinary nickel were 3.57 (1.73–7.36) for the second quartile, 3.61 (1.83–7.13) for the third quartile, and 2.40 (1.03–5.59) for the fourth quartile. Cubic spline regression revealed a non-monotonic, inverse U-shaped, association between urinary nickel and CVD (Pnonlinearity < 0.001). Conclusions Nickel exposure is associated with CVD in a non-monotonic manner among U.S. adults independent of well-known CVD risk factors.
      PubDate: 2024-04-01
       
  • PAH Pollution in Particulate Matter and Risk in Chinese Cities

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      Abstract: Abstract In China, with the largest population and known as the world's factory, the study of air pollution trends can provide an important reference value for the world's population and manufacturing countries. In particular, the polycyclic aromatic hydrocarbon (PAH) pollution status in particulate matter can accurately reflect the dynamic balance between the atmosphere and sediments and the risks to people and ecology. This study combined 85 publications with over 6971 individual samples from 219 sites in 89 Chinese cities. The findings were first integrated into a unified database of the spatial distribution of the PAH concentration. The results revealed that the parent PAH concentration and pollution in atmospheric particulates greatly increased in Chinese cities (> 500 thousand people). The contamination levels, as indicated by the toxic equivalent quantity, incremental lifetime cancer risk, hazard index, and ecological risk, were higher in northern China (NC) than in southern China (SC). The health risk of subpopulations followed the cohort order of juveniles (≤ 18) < adults (> 18). The risk quotient and sediment quality guidelines showed that certain individual PAHs could occasionally pose an ecological risk in some cities, especially in NC. The results of the mean effect range median quotient suggested that the combined negative ecological effects of ∑16PAHs resulted in high (NC) and moderate (SC) risks. The ecological risk level in 73 cities in China was above the moderate level, which is mainly controlled by the source of coal for residential heating and heavy industry, automobile exhaust and light industries in NC and SC, respectively.
      PubDate: 2024-04-01
       
  • Residues of Polycyclic Aromatic Hydrocarbons in Breast Milk Collected from
           Jinhua (China) and the Influence of Exercise Habit: Levels and the
           Potential Health Effects

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      Abstract: Abstract Breast milk is one of the best biological media to identify the pollutant exposure and the associated health risk. This study investigated the residues of 16 polycyclic aromatic hydrocarbons (PAHs) in breast milk of the general population from Jinhua, China. The potential influencing factors as well as the potential health effects on infants and mothers were analyzed. Results shows that only four of the 16 PAH species were detectable, and their mean concentrations were ranked as naphthalene (52.4 ng/g lipid) > phenanthrene (38.6 ng/g lipid) > fluoranthene (4.5 ng/g lipid) > pyrene (1.4 ng/g lipid). The average level of total PAHs was 97.0 ng/g lipid, which was lower when compared to other areas and countries. The statistical analysis showed that parity, especially the exercise habit was the key factor influencing PAH residue in breast milk. Women with first birth tended to have higher PAH levels. Frequent physical exercising can lower down PAH levels, reduce PAHs detection rate, and decrease PAH species in breast milk. The estimated daily intake of PAHs for infants through breast milk was 0.262 [not detectable (ND)–1.008] ng/kg bwt/day BaP in often-exercise group, and 0.544 (ND–1.568) ng/kg bwt/day BaP in seldom-exercise group, which were well below the regulated values set by UK, USEPA, JECFA and EFSA. However, the cancer risk of infants in the seldom-exercise group (1.9 × 10−6) exceeded the acceptable level of 10−6. Correlation analysis also revealed that PAHs residues in mother have no potential adverse effects on fetal growth, but may be linked with dysmenorrhea of mother. The results of this study provided valuable knowledge for mitigating the potential hazards of PAHs exposure to mothers and infants, and can serve as a fundamental basis for devising effective prevention and control measures aimed at minimizing PAHs exposure.
      PubDate: 2024-04-01
       
  • Long-Term and Multipoint Observations of Atmospheric Heavy Metal (Cu and
           Cd) Deposition and Accumulation in Soil–Crop System and Human Health
           Risk Evaluation Around a Large Smelter

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      Abstract: Abstract The atmospheric deposition of copper (Cu) and cadmium (Cd) was monitored over 79 months to investigate the fluxes and influencing factors and to partition the possible health risk between new deposition and legacy heavy metals in ten locations surrounding a Cu smelter. The results showed annual Cu and Cd deposition fluxes ranged from 7.6- to 81-folds (113–1309 mg m–2) and from 2.7- to 12-folds (2.8–9.5 mg m–2) higher than those in the background site, respectively. The direct exposure to heavy metals via inhalation of the atmospheric deposition was negligible, but the indirect exposure from new deposition and then accumulation in crops via dietary crop intake was the primary pathway. Principal component analysis (PCA) and redundancy analysis showed the rate of wind frequency and distance to the point source were critical driving factors affecting the spatial flux distribution. High atmospheric deposition and legacy soil contamination resulted in rice Cd concentrations higher than the national thresholds and rice ingestion was the primary exposure pathway. Multiple pathways provided potential non-carcinogenic risk posed by Cu and Cd, especially for Cd. Current atmospheric deposition via indirect exposure contributed to about 40% of the non-carcinogenic risk, although it only accounted for 0.22–0.88% and 0.96–2.5% of Cu and Cd pools in the soil plow layer (0–20 cm). Legacy soil Cu and Cd contributed 60% of the non-carcinogenic risk. These findings implicate that reduction of anthropogenic emission and atmospheric deposition should be considered as effective environmental management to reduce the human heavy metal exposure in typical areas influenced by substantial deposition loads.
      PubDate: 2024-04-01
       
 
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  Subjects -> HEALTH AND SAFETY (Total: 1464 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (686 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (358 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (112 journals)
    - PHYSICAL FITNESS AND HYGIENE (117 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (686 journals)            First | 1 2 3 4     

Showing 601 - 203 of 203 Journals sorted alphabetically
Safety     Open Access   (Followers: 2)
Safety and Health at Work     Open Access   (Followers: 75)
Safety and Reliability     Hybrid Journal   (Followers: 4)
Safety in Extreme Environments     Hybrid Journal  
Safety in Health     Open Access   (Followers: 74)
Saintika Medika     Open Access  
Salud & Sociedad: investigaciones en psicologia de la salud y psicologia social     Open Access  
Salud Areandina     Open Access  
Salud Colectiva     Open Access  
Salud(i)ciencia     Open Access  
Salus     Open Access  
Salute e Società     Full-text available via subscription  
Samsun Sağlık Bilimleri Dergisi     Open Access  
Saúde Coletiva     Open Access  
Saúde e Meio Ambiente : Revista Interdisciplinar     Open Access  
Saúde em Redes     Open Access  
Saúde.com     Open Access  
Scandinavian Journal of Work, Environment & Health     Partially Free   (Followers: 13)
School Mental Health     Hybrid Journal   (Followers: 10)
Scientia Medica     Open Access  
Scire Salutis     Open Access  
Serviço Social e Saúde     Open Access  
Sextant : Revue de recherche interdisciplinaire sur le genre et la sexualité     Open Access  
Sexual Health     Hybrid Journal   (Followers: 5)
Sexual Medicine Reviews     Full-text available via subscription   (Followers: 2)
Sierra Leone Journal of Biomedical Research     Open Access  
Sleep and Vigilance : An International Journal of Basic, Translational and Clinical Research     Hybrid Journal   (Followers: 1)
Sleep Health     Full-text available via subscription   (Followers: 5)
Sleep Science and Practice     Open Access   (Followers: 10)
SMAD, Revista Electronica en Salud Mental, Alcohol y Drogas     Open Access   (Followers: 2)
Smart Health     Hybrid Journal  
Social Determinants of Health     Open Access   (Followers: 2)
Social Theory & Health     Hybrid Journal   (Followers: 3)
Social Work in Health Care     Hybrid Journal   (Followers: 26)
Social Work in Mental Health     Hybrid Journal   (Followers: 16)
Social Work in Public Health     Hybrid Journal   (Followers: 13)
Society, Health & Vulnerability     Open Access   (Followers: 4)
Sosiaalilääketieteellinen Aikakauslehti     Open Access  
South African Family Practice     Open Access   (Followers: 3)
South African Journal of Bioethics and Law     Open Access   (Followers: 1)
South African Journal of Child Health     Open Access   (Followers: 1)
South African Journal of Communication Disorders     Open Access   (Followers: 1)
South East Asia Journal of Public Health     Open Access   (Followers: 3)
South Eastern European Journal of Public Health     Open Access   (Followers: 1)
Southern African Journal of Critical Care     Open Access   (Followers: 4)
Southern African Journal of Public Health     Open Access  
Southwest Respiratory and Critical Care Chronicles     Open Access   (Followers: 1)
Space Safety Magazine     Free   (Followers: 49)
Sri Lanka Journal of Child Health     Open Access  
SSM - Population Health     Open Access   (Followers: 5)
SSM - Qualitative Research in Health     Open Access   (Followers: 2)
Stigma and Health     Full-text available via subscription   (Followers: 2)
Sundhedsprofessionelle studier     Open Access  
Sustainable Earth     Open Access   (Followers: 2)
Sustinere : Revista de Saúde e Educação     Open Access  
System Safety : Human - Technical Facility - Environment     Open Access   (Followers: 3)
Systematic Reviews     Open Access   (Followers: 14)
Tanzania Journal of Health Research     Open Access   (Followers: 2)
Technology and Innovation     Full-text available via subscription   (Followers: 2)
Tempus Actas de Saúde Coletiva     Open Access  
Textos & Contextos (Porto Alegre)     Open Access  
The Journal of Aquatic Physical Therapy     Full-text available via subscription   (Followers: 4)
The Journal of Rural Health     Hybrid Journal   (Followers: 5)
The Lancet Child & Adolescent Health     Hybrid Journal   (Followers: 10)
The Lancet Global Health     Open Access   (Followers: 74)
The Lancet Planetary Health     Open Access   (Followers: 5)
The Lancet Regional Health : Americas     Open Access  
The Lancet Regional Health : Europe     Open Access   (Followers: 3)
The Lancet Regional Health : Southeast Asia     Open Access   (Followers: 8)
The Lancet Regional Health : Western Pacific     Open Access   (Followers: 2)
The Meducator     Open Access   (Followers: 1)
Theoretical Issues in Ergonomics Science     Hybrid Journal   (Followers: 9)
Therapeutic Communities : The International Journal of Therapeutic Communities     Hybrid Journal   (Followers: 17)
Tidsskrift for Forskning i Sygdom og Samfund     Open Access  
Tidsskrift for psykisk helsearbeid     Full-text available via subscription  
Tobacco Control     Hybrid Journal   (Followers: 16)
Tobacco Control and Public Health in Eastern Europe     Open Access   (Followers: 3)
Transgender Health     Open Access   (Followers: 4)
Transportation Safety and Environment     Open Access   (Followers: 1)
Tropical Journal of Health Sciences     Full-text available via subscription  
Tropical Medicine and Health     Open Access   (Followers: 2)
TÜBAV Bilim Dergisi     Open Access  
Universal Journal of Public Health     Open Access  
Universidad y Salud     Open Access  
Unnes Journal of Public Health     Open Access  
Value in Health Regional Issues     Hybrid Journal  
Vascular Health and Risk Management     Open Access   (Followers: 2)
Vigilância Sanitária em Debate     Open Access  
Violence and Gender     Full-text available via subscription   (Followers: 22)
Water Quality, Exposure and Health     Hybrid Journal   (Followers: 2)
Western Pacific Surveillance and Response     Open Access  
Women & Health     Hybrid Journal   (Followers: 10)
World Health & Population     Full-text available via subscription   (Followers: 3)
World Medical & Health Policy     Hybrid Journal   (Followers: 2)
Zeitschrift für Arbeitswissenschaft     Hybrid Journal  
Zoonotic Diseases     Open Access   (Followers: 24)
Електромагнітна сумісність та безпека на залізничному транспорті     Open Access  
مجله بهداشت و توسعه     Open Access  

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