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Egyptian Journal of Critical Care Medicine
Number of Followers: 2  Open Access journalISSN (Print) 2090-7303 Published by LWW Wolters Kluwer  [330 journals]
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- The Association Between Plasma C-Type Lectin Like Receptors 2 (CLEC-2) and
STEMI and its Correlation With Clinicolaboratory Data
Authors: Ahmed; Salwa Hassan; ElSayed, Ahmed Abd ElMoez; Abdel Maksoud, Fatma Abdel Wahab; Fathi, Lamees Mohamed; Soliman, Soliman Belal
Abstract:
Objectives: To assess the association between plasma C-type lectin-like receptor 2 (CLEC-2) and ST elevation myocardial infarction (STEMI) and its correlation with clinicolaboratory data.Methods: This case-control study included 88 individuals divided into two groups. Group I (the cases group): 50 patients diagnosed with STEMI. Group II (control group): 38 sex-matched and age-matched healthy individuals. All patients were subjected to the assessment of CLEC-2, using enzyme-linked immunosorbent assay (ELIZA) kit.Results: CLEC-2 levels in group I were higher than group II (P value 121, area under the curve 0.73, sensitivity 76%, specificity 63.2% (P < 0.001), 95 CI (0.63–0.84).Conclusions: CLEC-2 levels can be used as a diagnostic marker but not suitable to be a prognostic factor.
PubDate: Sun, 01 Oct 2023 00:00:00 GMT-
- Lung Ultrasound Score for Prediction of Weaning Outcome From Mechanical
Ventilation
Authors: Faris; Farouk Mostafa; Sarabana, Ayman Atef; Mohamed abd elwahab, Kamel; Nawar, Mahmoud Saad
Abstract:
Introduction: Failure of extubation of patients on mechanical ventilation is one of the common problems in the intensive care unit (ICU).Aim of work: To evaluate the validity of lung ultrasound score in prediction of weaning outcomes and postextubation distress.Methods: A prospective cohort observational study of 50 patients planned for extubation after a spontaneous breathing trial. Lung ultrasound score and serum level of NT-PROBNP were performed before extubation. All patients were followed for oxygenation, re-intubation rate, ICU stay and ICU mortality.Results: The mean age of the study population was 61.26 ± 12.9 years; the lung ultrasound score was higher in the failed extubation group than the successful extubation group. The cutoff value of lung ultrasound score for prediction of successful extubation was 15.5 (the area under the curve: 0.851; 95% confidence interval: 0.721–0.981) with the sensitivity and specificity of 90% and 75%, respectively. Increased duration of controlled mechanical ventilation was associated with high extubation failure. Extubation failure is associated with prolonged ICU stay and an increase in ICU mortality.Conclusion: Lung ultrasound score may be valid in prediction of postextubation distress with high sensitivity and specificity. Postextubation distress is associated with prolonged ICU stay and higher mortality rate.
PubDate: Sun, 01 Oct 2023 00:00:00 GMT-
