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- A circular mRNA vaccine prototype producing VFLIP-X spike confers a broad
neutralization of SARS-CoV-2 variants by mouse sera-
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Abstract: Publication date: Available online 27 June 2022Source: Antiviral ResearchAuthor(s): Chotiwat Seephetdee, Kanit Bhukhai, Nattawut Buasri, Puttipatch Leelukkanaveera, Pat Lerdwattanasombat, Suwimon Manopwisedjaroen, Nut Phueakphud, Sakonwan Kuhaudomlarp, Eduardo Olmedillas, Erica Ollmann Saphire, Arunee Thitithanyanont, Suradej Hongeng, Patompon Wongtrakoongate
- 27-Hydroxycholesterol inhibits rhinovirus replication in vitro and on
human nasal and bronchial histocultures without selecting viral resistant
variants-
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Abstract: Publication date: August 2022Source: Antiviral Research, Volume 204Author(s): Andrea Civra, Matteo Costantino, Roberta Cavalli, Marco Adami, Marco Volante, Giuseppe Poli, David Lembo
- Long-term and efficient inhibition of hepatitis B virus replication by
AAV8-delivered artificial microRNAs-
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Abstract: Publication date: August 2022Source: Antiviral Research, Volume 204Author(s): Yingying Mao, Xuejun Wang, Wei Hu, Andrew Li, Ying Li, Hai Huang, Renhe Yan, Yanling Zhang, Jinlong Li, Hongwei Li, Shengqi Wang
- Numb-associated kinases are required for SARS-CoV-2 infection and are
cellular targets for antiviral strategies-
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Abstract: Publication date: Available online 20 June 2022Source: Antiviral ResearchAuthor(s): Marwah Karim, Sirle Saul, Luca Ghita, Malaya Kumar Sahoo, Chengjin Ye, Nishank Bhalla, Chieh Wen Lo, Jing Jin, Jun-Gyu Park, Belén Martinez-Gualda, Michael Patrick East, Gary L. Johnson, Benjamin A. Pinsky, Luis Martinez-Sobrido, Christopher R.M. Asquith, Aarthi Narayanan, Steven De Jonghe, Shirit Einav
- Influenza A virus polymerase acidic protein E23R substitution is a marker
of reduced susceptibility to baloxavir-
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Abstract: Publication date: Available online 20 June 2022Source: Antiviral ResearchAuthor(s): Jeremy C. Jones, Samuel W. Rovito, Melissa K. Penaflor, Richard J. Webby, Elena A. Govorkova
- Bergamottin, a bioactive component of bergamot, inhibits SARS-CoV-2
infection in golden Syrian hamsters-
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Abstract: Publication date: Available online 19 June 2022Source: Antiviral ResearchAuthor(s): Minmin Zhou, Yang Liu, Junyuan Cao, Siqi Dong, Yuxia Hou, Yan Yu, Qiuyan Zhang, Yueli Zhang, Xiaoying Jia, Bo Zhang, Gengfu Xiao, Gang Li, Wei Wang
- Identification of structurally re-engineered rocaglates as inhibitors
against hepatitis E virus replication-
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Abstract: Publication date: Available online 18 June 2022Source: Antiviral ResearchAuthor(s): Dimas F. Praditya, Mara Klöhn, Yannick Brüggemann, Lauren E. Brown, John A. Porco, Wenhan Zhang, Volker Kinast, Andreas Kirschning, Florian W.R. Vondran, Daniel Todt, Eike Steinmann
- Identification of potent inhibitors of arenavirus and SARS-CoV-2
exoribonucleases by fluorescence polarization assay-
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Abstract: Publication date: Available online 16 June 2022Source: Antiviral ResearchAuthor(s): Sergio Hernández, Mikael Feracci, Carolina Trajano De Jesus, Priscila El Kazzi, Rafik Kaci, Laura Garlatti, Clemence Mondielli, Fabrice Bailly, Philippe Cotelle, Franck Touret, Xavier de Lamballerie, Bruno Coutard, Etienne Decroly, Bruno Canard, François Ferron, Karine Alvarez
- Poloxamer 188 – quercetin formulations amplify in vitro ganciclovir
antiviral activity against cytomegalovirus-
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Abstract: Publication date: Available online 13 June 2022Source: Antiviral ResearchAuthor(s): Andrew Kjar, Ian Wadsworth, Elizabeth Vargis, David W. Britt
- Liver biopsy of chronic hepatitis B patients indicates HBV integration
profile may complicate the endpoint and effect of entecavir treatment-
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Abstract: Publication date: Available online 13 June 2022Source: Antiviral ResearchAuthor(s): Mingyuan Zhang, Haikun Zhang, Xiaoming Cheng, Xiaomei Wang, Hongqin Xu, Xiuzhu Gao, Ruihong Wu, Dake Zhang, Yuchen Xia, Junqi Niu
- First clinical description of letermovir resistance mutation in
cytomegalovirus UL51 gene and potential impact on the terminase complex
structure.-
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Abstract: Publication date: Available online 9 June 2022Source: Antiviral ResearchAuthor(s): Clotilde Muller, Valentin Tilloy, Emilie Frobert, Linda Feghoul, Isabelle Garrigue, Quentin Lepiller, Audrey Mirand, Egor Sidorov, Sébastien Hantz, Sophie Alain
- Conserved coronavirus proteins as targets of broad-spectrum antivirals
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Abstract: Publication date: Available online 9 June 2022Source: Antiviral ResearchAuthor(s): Cleber C. Melo-Filho, Tesia Bobrowski, Holli-Joi Martin, Zoe Sessions, Konstantin Popov, Nathaniel J. Moorman, Ralph S. Baric, Eugene N. Muratov, Alexander Tropsha
- Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro
by virtual screenings and hit optimization-
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Abstract: Publication date: Available online 7 June 2022Source: Antiviral ResearchAuthor(s): Beatrice Mercorelli, Jenny Desantis, Marta Celegato, Alessandro Bazzacco, Lydia Siragusa, Paolo Benedetti, Michela Eleuteri, Federico Croci, Gabriele Cruciani, Laura Goracci, Arianna Loregian
- A novel high-throughput single B-cell cloning platform for isolation and
characterization of high-affinity and potent SARS-CoV-2 neutralizing
antibodies-
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Abstract: Publication date: Available online 28 May 2022Source: Antiviral ResearchAuthor(s): Paritosh Prashar, Sonali Swain, Nisha Adhikari, Punit Aryan, Anupama Singh, Mohit Kwatra, Prabhakar B
- Characterization of the tenofovir resistance-associated mutations in the
hepatitis B virus isolates across genotypes A to D-
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Abstract: Publication date: Available online 27 May 2022Source: Antiviral ResearchAuthor(s): Tingting Liu, Qingsong Sun, Jiaqi Gu, Shan Cen, Quan Zhang
- Hemin protects against Zika virus infection by disrupting virus-endosome
fusion-
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Abstract: Publication date: Available online 26 May 2022Source: Antiviral ResearchAuthor(s): Meng-Meng Xu, Bing Wu, Guan-Gen Huang, Chun-Lan Feng, Xiao-Han Wang, Hao-Yu Wang, Yan-Wei Wu, Wei Tang
- Animal models for studying coronavirus infections and developing antiviral
agents and vaccines-
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Abstract: Publication date: Available online 21 May 2022Source: Antiviral ResearchAuthor(s): Qisheng Lin, Chunni Lu, Yuqi Hong, Runfeng Li, Jinding Chen, Weisan Chen, Jianxin Chen
- TLR2-mediated mucosal immune priming boosts anti-rhabdoviral immunity in
early vertebrates-
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Abstract: Publication date: Available online 21 May 2022Source: Antiviral ResearchAuthor(s): Chen Zhang, Zhao Zhao, Peng-Qi Zhang, Sheng Guo, Bin Zhu
- Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by
high-throughput screening-
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Abstract: Publication date: Available online 19 May 2022Source: Antiviral ResearchAuthor(s): Anu Roy, Yousef M. Alhammad, Peter McDonald, David K. Johnson, Junlin Zhuo, Sarah Wazir, Dana Ferraris, Lari Lehtiö, Anthony K.L. Leung, Anthony R. Fehr
- Immunodetection assays for the quantification of seasonal common cold
coronaviruses OC43, NL63, or 229E infection confirm nirmatrelvir as broad
coronavirus inhibitor-
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Abstract: Publication date: Available online 19 May 2022Source: Antiviral ResearchAuthor(s): Tatjana Weil, Jan Lawrenz, Alina Seidel, Jan Münch, Janis A. Müller
- SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral
screening-
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Abstract: Publication date: Available online 18 May 2022Source: Antiviral ResearchAuthor(s): Emiel Vanhulle, Joren Stroobants, Becky Provinciael, Anita Camps, Sam Noppen, Piet Maes, Kurt Vermeire
- Remdesivir efficacy against yellow fever in a hamster model
-
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Abstract: Publication date: Available online 6 May 2022Source: Antiviral ResearchAuthor(s): Justin G. Julander, Elaine Bunyan, Robert Jordan, Danielle P. Porter
- Development of a cost-effective ovine antibody-based therapy against
SARS-CoV-2 infection and contribution of antibodies specific to the spike
subunit proteins-
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Abstract: Publication date: Available online 6 May 2022Source: Antiviral ResearchAuthor(s): Stephen Findlay-Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Gareth Humphries, Holger Schuhmann, Didier Ngabo, Emma Rayner, Ashley David Otter, Tom Coleman, Bethany Hicks, Victoria Anne Graham, Rachel Halkerston, Kostis Apostolakis, Stephen Taylor, Susan Fotheringham, Amanda Horton, Julia Anne Tree, Matthew Wand, Roger Hewson
- Sulfated β-glucan from Agaricus subrufescens inhibits flavivirus
infection and nonstructural protein 1-mediated pathogenesis-
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Abstract: Publication date: Available online 6 May 2022Source: Antiviral ResearchAuthor(s): Francielle Tramontini Gomes de Sousa, Scott B. Biering, Trishna S. Patel, Sophie F. Blanc, Carla Maisa Camelini, Dalila Venzke, Ricardo Nunes, Camila Malta Romano, P. Robert Beatty, Ester Cerdeira Sabino, Eva Harris
- Intravenous delivery of GS-441524 is efficacious in the African green
monkey model of SARS-CoV-2 infection-
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Abstract: Publication date: Available online 5 May 2022Source: Antiviral ResearchAuthor(s): Jared Pitts, Darius Babusis, Meghan S. Vermillion, Raju Subramanian, Kim Barrett, Diane Lye, Bin Ma, Xiaofeng Zhao, Nicholas Riola, Xuping Xie, Adriana Kajon, Xianghan Lu, Roy Bannister, Pei-Yong Shi, Maria Toteva, Danielle P. Porter, Bill J. Smith, Tomas Cihlar, Richard Mackman, John P. Bilello
- Cytomegalovirus variation among newborns treated with valganciclovir
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Abstract: Publication date: Available online 30 April 2022Source: Antiviral ResearchAuthor(s): G. Clement Dobbins, David Kimberlin, Shannon Ross
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