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- Strategies for Enhancing Non-small Cell Lung Cancer Treatment: Integrating
Chinese Herbal Medicines with Epidermal Growth Factor Receptor-Tyrosine
Kinase Inhibitors Therapy-
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Abstract: Publication date: Available online 6 August 2024Source: European Journal of PharmacologyAuthor(s): Lin Chen, Wen-Da Chen, Yu-Xin Xu, Ying-Ying Ren, Cheng Zheng, Yuan-Yuan Lin, Jian-Liang Zhou
- Pharmacological characterization of the zebrafish Hrh2a histamine
H2 receptor-
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Abstract: Publication date: Available online 6 August 2024Source: European Journal of PharmacologyAuthor(s): Daniel A. McNaught-Flores, Yu-Chia Chen, Jose-Antonio Arias-Montaño, Pertti Panula, Rob Leurs
- Emerging paradigms in Alzheimer’s Therapy
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Abstract: Publication date: Available online 6 August 2024Source: European Journal of PharmacologyAuthor(s): Agnes Preethy H, Kayalvizhi Rajendran, Anitha Josephine Sukumar, Uma Maheswari Krishnan
- Emerging pharmacological approaches for Huntington's disease
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Abstract: Publication date: Available online 6 August 2024Source: European Journal of PharmacologyAuthor(s): Kuldeep Singh, Divya Jain, Pranshul Sethi, Jeetendra Kumar Gupta, Arpan Kumar Tripathi, Shivendra Kumar, Satyajit D. Sarker, Lutfun Nahar, Ajay Guru
- Flibanserin conquers murine depressive pseudodementia by amending HPA
axis, maladaptive inflammation and AKT/GSK/STAT/BDNF trajectory:
center-staging of the serotonergic/adrenergic circuitry-
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Abstract: Publication date: Available online 6 August 2024Source: European Journal of PharmacologyAuthor(s): Doaa A. Zaky, Kareema A. Mehny, Sahar S. Abdelrahman, Mohamed El Yamani, Ahmed S. Kamel
- Inhibition of MARCKS phosphorylation attenuates of dendritic cell
migration in a murine model of acute asthma-
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Abstract: Publication date: Available online 5 August 2024Source: European Journal of PharmacologyAuthor(s): Chen-Chen Lee, Ching-Hsien Chen, Nicholas J. Kenyon, Chien-Neng Wang, Hsing-Chuan Tsai, Chun-Lung Chiu, Yin Chen, Rosanna M. Forteza, Reen Wu
- Pre-treatment with tocilizumab reduces lipopolysaccharide-induced acute
lung injury in biliary cirrhotic rats-
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Abstract: Publication date: 5 October 2024Source: European Journal of Pharmacology, Volume 980Author(s): Shao-Jung Hsu, Kuang-Yao Yang, Hui-Chun Huang, Chiao-Lin Chuang, Ching-Chih Chang, Chon-Kit Pun, Ming-Chih Hou, Fa-Yauh Lee
- “Sigma-1 receptor modulation by clemastine highlights its repurposing as
neuroprotective agent against seizures and cognitive deficits in
PTZ-kindled rats”-
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Abstract: Publication date: 5 October 2024Source: European Journal of Pharmacology, Volume 980Author(s): Ghada A. Badawi, Mustafa M. Shokr, Shimaa M. Elshazly, Hala F. Zaki, Ahmed F. Mohamed
- Vitexin promotes the anti-senescence effect via inhibiting JAK2/STAT3 in
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Abstract: Publication date: 5 October 2024Source: European Journal of Pharmacology, Volume 980Author(s): Xiaojuan Han, Lu Li, Jiamei Xie, Qing Lei, Yansong Li, Huan Liu, Haoran Sun, Xiaohua Zhang, Xingchun Gou
- MFN2-dependent mitochondrial dysfunction contributes to Relm-β-induced
pulmonary arterial hypertension via USP18/Twist1/miR-214 pathway-
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Abstract: Publication date: Available online 31 July 2024Source: European Journal of PharmacologyAuthor(s): Yan Wang, Dong Han, Limin Chai, Yuanjie Qiu, Jin Liu, Danyang Li, Qianqian Zhang, Nirui Shen, Yuqian Chen, Huan Chen, Jia Zhang, Qingting Wang, Jian Wang, Shaojun Li, Xinming Xie, Manxiang Li
- Molecular mechanisms of PTEN in atherosclerosis: A comprehensive review
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Abstract: Publication date: Available online 31 July 2024Source: European Journal of PharmacologyAuthor(s): Yuan Tian, Yi-Fan Liu, Yan-Yue Wang, Yong-Zhen Li, Wen-Yan Ding, Chi Zhang
- Hypnotic effect of AR-001 through adenosine A1 receptor
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Abstract: Publication date: Available online 31 July 2024Source: European Journal of PharmacologyAuthor(s): Suyeon Kim, Hye Jin Jee, Ju-Young Park, Sung Hun Bae, So Hee Kim, Eunha Kim, Sunghou Lee, Yi-Sook Jung
- Vitexin attenuates neuropathic pain by regulating astrocyte autophagy flux
and polarization via the S1P/ S1PR1-PI3K/ Akt axis-
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Abstract: Publication date: Available online 31 July 2024Source: European Journal of PharmacologyAuthor(s): Kesheng Huang, Ruifeng Ding, Chengyuan Lai, Haowei Wang, Xiaoyi Fan, Yan Chu, Yuanyuan Fang, Tong Hua, Hongbin Yuan
- Imperatorin attenuates CCl4-induced cirrhosis and portal hypertension by
improving vascular remodeling and profibrogenic pathways-
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Abstract: Publication date: Available online 31 July 2024Source: European Journal of PharmacologyAuthor(s): Zhifeng Zhao, Qiang Fan, Chihao Zhang, Lei Zheng, Jiayun Lin, Min Chen, Guangbo Wu, Hongjie Li, Haizhong Huo, Qingchuan Zhao, Meng Luo
- The role of heterodimers formed by histamine H3 receptors and dopamine D1
receptors on the methamphetamine-induced conditioned place preference-
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Abstract: Publication date: Available online 30 July 2024Source: European Journal of PharmacologyAuthor(s): Runyue Fan, Xinshuang Gong, Zhaoyin Yu, Shujun Lin, Yuer Ruan, Liyin Qian, Zizhen Si, Longhui Li, Wenhua Zhou, Yu Liu
- Lipidized analogues of the anorexigenic CART (cocaine- and
amphetamine-regulated transcript) neuropeptide show anorexigenic and
neuroprotective potential in mouse model of monosodium-glutamate induced
obesity-
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Abstract: Publication date: Available online 30 July 2024Source: European Journal of PharmacologyAuthor(s): Vilém Charvát, Anna Strnadová, Aneta Myšková, David Sýkora, Miroslava Blechová, Blanka Železná, Jaroslav Kuneš, Lenka Maletínská, Andrea Pačesová
- CDK8/19 inhibitor enhances arginase-1 expression in macrophages via STAT6
and p38 MAPK activation-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Natsumi Mizuno, Saki Shiga, Yoshiyuki Tanaka, Tatsuki Kimura, Yoshiki Yanagawa
- Exploring the potential mechanism of ginsenoside Rg1 to regulate
ferroptosis in Alzheimer's disease based on network pharmacology-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Xu Deng, Zixiong Qiu, Xiaoshuai Chen, Jiangxiu Liu, Xiaowei Wang, Jie Li, Jiankai Zhang, Xiaojun Cui, Yuan Fu, Mei Jiang
- TRIM16 mitigates impaired osteogenic differentiation and antioxidant
response in D-galactose-induced senescent osteoblasts-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Kai Li, Ke Huang, Quanyi Lu, Wenbo Geng, Dianming Jiang, Ai Guo
- Pharmacological activation of pyruvate dehydrogenase by dichloroacetate
protects against obesity-induced muscle atrophy in vitro and in vivo-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Jung-Mou Yang, I-Shan Han, Tsung-Hua Chen, Po-Shiuan Hsieh, Min-Chien Tsai, Hung-Che Chien
- Role of cardiolipin in regulating and treating atherosclerotic
cardiovascular diseases-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Jin Wei, Meng Zhang, Xia Wang, Kaiying Yang, Qi Xiao, Xiaoyan Zhu, Xudong Pan
- Heart Failure with Preserved Ejection Fraction: The Role of Inflammation
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Abstract: Publication date: Available online 27 July 2024Source: European Journal of PharmacologyAuthor(s): Hongyi Liu, Ruth Magaye, David M. Kaye, Bing H. Wang
- Carbon Monoxide Attenuates Cellular Senescence-mediated Pulmonary Fibrosis
via Modulating p53/PAI-1 Pathway-
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Abstract: Publication date: Available online 27 July 2024Source: European Journal of PharmacologyAuthor(s): Qianqian Wang, Aohan Li, Qian Li, Jiaxin Li, Qi Wang, Siyuan Wu, Jiaojiao Meng, Changpeng Liu, Dan Wang, Yingqing Chen
- Investigating Cannabidiol’s Potential as a Supplementary Treatment for
Schizophrenia: A Narrative Review-
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Abstract: Publication date: Available online 27 July 2024Source: European Journal of PharmacologyAuthor(s): Jes Sebastian Denis Völker, M.D.Ph.D. Ioana Valentina Micluția, Ramona-Cristina Vinași
- Overexpression of miR-20a-5p in mesenchymal stem cell derived-exosomes
from systemic lupus erythematosus patients restored therapeutic effect and
Treg immune regulation-
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Abstract: Publication date: Available online 26 July 2024Source: European Journal of PharmacologyAuthor(s): Juan Ji, Qian Liang, Qian He, Tian Chen, Guijuan Feng, Hua Guo, Yunan Wang, Yongxin Xu, Pengyu Chen, Chen Dong, Rui Zhao, Junling Yang, Xiaoqi Sha, Haixia Cao, Jing Li, Yunfei Xia, Mei Yang, Zhifeng Gu
- The Mitragyna speciosa (kratom) alkaloid mitragynine: analysis of
adrenergic α2 receptor activity in vitro and in vivo-
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Abstract: Publication date: Available online 26 July 2024Source: European Journal of PharmacologyAuthor(s): Samuel Obeng, Morgan L. Crowley, Marco Mottinelli, Francisco León, Julio D. Zuarth Gonzalez, Yiming Chen, Lea R. Gamez-Jimenez, Luis F. Restrepo, Nicholas P. Ho, Avi Patel, Joelma Martin-Rocha, Manuel A. Alvarez, Amsha M. Thadisetti, Chai R. Park, Victoria L.C. Pallares, Megan J. Milner, Clinton E. Canal, Aidan J. Hampson, Christopher R. McCurdy, Lance R. McMahon
- Efficacy of GluN2B-Containing NMDA Receptor Antagonist for Antitumor and
Antidepressant Therapy in Non-small Cell Lung Cancer-
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Abstract: Publication date: Available online 26 July 2024Source: European Journal of PharmacologyAuthor(s): Weiming Bian, Ye Chen, Yanjie Ni, Bihua Lv, Bo Gong, Kaiyuan Zhu, Wei Gao, Linghui Zeng, Wen Lu, Bin Zhang
- From Defense to Dysfunction: Autophagy's Dual Role in Disease
Pathophysiology-
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Abstract: Publication date: Available online 26 July 2024Source: European Journal of PharmacologyAuthor(s): Jonaid Ahmad Malik, Mohammad Adeel Zafar, Sanpreet Singh, Sidhanta Nanda, Hilal Bashir, Deepjyoti Kumar Das, Taruna Lamba, Mohammad Affan Khan, Gurpreet Kaur, Javed N. Agrewala
- Potential Role of Remimazolam in Alleviating Bone Cancer Pain in Mice via
Modulation of Translocator Protein in Spinal Astrocytes-
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Abstract: Publication date: Available online 26 July 2024Source: European Journal of PharmacologyAuthor(s): Yuan Peng, Yuxin Zhang, Wei Wang, Biying Liu, Zuojing Zhang, Zhihao Gong, Xiaoxuan Zhang, Yuefeng Xia, Xingji You, Jingxiang Wu
- PHARMACOLOGICAL AGENTS TARGETING TRANSIENT RECEPTOR POTENTIAL (TRP)
CHANNELS IN NEUROPATHIC PAIN: PRECLINICAL AND CLINICAL STATUS-
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Abstract: Publication date: Available online 25 July 2024Source: European Journal of PharmacologyAuthor(s): Ashish Dangi, Shyam Sunder Sharma
- Aging in chronic lung disease: will anti-aging therapy be the key to the
cure'-
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Abstract: Publication date: Available online 25 July 2024Source: European Journal of PharmacologyAuthor(s): Weijie Wang, Kai Zhou, Leyuan Wang, Qiuyan Qin, Huijun Liu, Ling Qin, Ming Yang, Lin Yuan, Chi Liu
- CircLMBR1 Inhibits Phenotypic Transformation of Hypoxia-induced Pulmonary
Artery Smooth Muscle via the Splicing Factor PUF60-
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Abstract: Publication date: Available online 25 July 2024Source: European Journal of PharmacologyAuthor(s): Hongdan Wang, Yupei Gao, June Bai, Huiyu Liu, Yiying Li, Junting Zhang, Cui Ma, Xijuan Zhao, Lixin Zhang, Kuiyu Wan, Daling Zhu
- Anti-inflammatory and antioxidant mechanisms of coniferaldehyde in
lipopolysaccharide-induced neuroinflammation: involvement of AMPK/Nrf2 and
TAK1/MAPK/NF-κB signaling pathways-
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Abstract: Publication date: Available online 25 July 2024Source: European Journal of PharmacologyAuthor(s): Jae-Min Park, Jung-Eun Park, Jin-Sun Park, Yea-Hyun Leem, Do-Yeon Kim, Jin-Won Hyun, Hee-Sun Kim
- Downregulation of stromal interaction molecule-1 is implicated in the
age-associated vasoconstriction dysfunction of aorta, intrarenal, and
coronary arteries-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Hao Wang, Peng Zeng, Peng-Hao Zhu, Zi-Fan Wang, Yong-Jiang Cai, Chun-Yu Deng, Hui Yang, Li-Ping Mai, Meng-Zhen Zhang, Su-Juan Kuang, Fang Rao, Jin-Song Xu
- Sacubitril/valsartan alleviates sepsis-induced myocardial injury in rats
via dual angiotensin receptor-neprilysin inhibition and modulation of
inflammasome/caspase 1/IL1β pathway-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Marwa Monier Mahmoud Refaie, Maram El-Hussieny, Asmaa M.A. Bayoumi, Wedad M. Abdelraheem, Elshymaa A. Abdel-Hakeem, Sayed Shehata
- Cepharanthine triggers ferroptosis through inhibition of NRF2 for robust
ER stress against lung cancer-
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Abstract: Publication date: 15 September 2024Source: European Journal of Pharmacology, Volume 979Author(s): Xiao-Feng Bai, Jun Hu, Mei-Fang Wang, Liu-Gen Li, Ning Han, Hansheng Wang, Nan-Nan Chen, Yu-Jie Gao, Hui You, Xiao Wang, Xiang Xu, Ting-Ting Yu, Tong-Fei Li, Tao Ren
- The impact of piperazine and antipsychotic co-exposures and CB1 blockade
on the effects elicited by AMB-FUBINACA, a synthetic cannabinoid, in mice.
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Abstract: Publication date: Available online 23 July 2024Source: European Journal of PharmacologyAuthor(s): Lucy R. Thomsen, Michelle Glass, Rhonda J. Rosengren
- Synergistic effect of osthole and notopterol combination against
Alzheimer's disease and osteoporosis by applying zebrafish AD/OP
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Abstract: Publication date: Available online 23 July 2024Source: European Journal of PharmacologyAuthor(s): Li-ying Guo, Ting Wang, Hou-xu Ma, Shihao Chen, Zhi-yong Chang, Fei Li
- A review of Novel Endothelin antagonists and overview of non-steroidal
mineralocorticoid antagonists for treating resistant hypertension: An
Update-
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Abstract: Publication date: Available online 22 July 2024Source: European Journal of PharmacologyAuthor(s): Olivia Blazek, George L. Bakris
- Novel Insights into the Regulation of Exosomal PD-L1 in Cancer: From
Generation to Clinical Application-
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Abstract: Publication date: Available online 22 July 2024Source: European Journal of PharmacologyAuthor(s): Jie Liu, Junxia Qin, Lili Liang, Xinzhong Zhang, Jie Gao, Youwei Hao, Peng Zhao
- NONO2P, a novel nitric oxide donor, causes vasorelaxation through
NO/sGC/PKG pathway, K+ channels opening and SERCA activation-
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Abstract: Publication date: Available online 22 July 2024Source: European Journal of PharmacologyAuthor(s): Raiana A. Moraes, Daniele S. Brito, Fênix A. Araujo, Rafael L.C. Jesus, Liliane B. Silva, Denise S. Sá, Carlos D. Silva da Silva, Laena Pernomian, Camilla F. Wenceslau, Fernanda Priviero, R. Clinton Webb, Darizy F. Silva
- Daphnetin alleviates allergic airway inflammation by inhibiting T-cell
activation and subsequent JAK/STAT6 signaling-
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Abstract: Publication date: Available online 20 July 2024Source: European Journal of PharmacologyAuthor(s): Ji-Yoon Park, Jae-Won Lee, Eun Sol Oh, Yu Na Song, Myung-Ji Kang, Hyung Won Ryu, Doo-Young Kim, Sei-Ryang Oh, Juhyun Lee, Jinseon Choi, Namho Kim, Mun-Ock Kim, Sung-Tae Hong, Su Ui Lee
- The role of novel protein acylations in cancer
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Abstract: Publication date: Available online 20 July 2024Source: European Journal of PharmacologyAuthor(s): Dan Cao, Wenxuan Sun, Xinyi Li, Lian Jian, Xinran Zhou, Ann M. Bode, Xiangjian Luo
- Comprehensive analysis of MAPK genes in the prognosis, immune
characteristics, and drug treatment of renal clear cell carcinoma using
bioinformatic analysis and Mendelian randomization-
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Abstract: Publication date: Available online 20 July 2024Source: European Journal of PharmacologyAuthor(s): Xinyi Zheng, Yiqiu Wang, Xiaoyan Qiu
- Evolving Significance of Kinase Inhibitors in the Management of
Alzheimer’s Disease-
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Abstract: Publication date: Available online 20 July 2024Source: European Journal of PharmacologyAuthor(s): Md Mustafiz Ansari, Sanjeev Kumar Sahu, Thakur Gurjeet Singh, SoviaRJ. Singh, Paranjeet Kaur
- Epidrugs in the clinical management of atherosclerosis: Mechanisms,
challenges and promises-
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Abstract: Publication date: Available online 20 July 2024Source: European Journal of PharmacologyAuthor(s): Sushma Panduga, Sampara Vasishta, Ramamoorthy Subramani, Sthevaan Vincent, Srinivas Mutalik, Manjunath B. Joshi
- Toll-like receptor 3 involvement in vascular function
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Abstract: Publication date: Available online 19 July 2024Source: European Journal of PharmacologyAuthor(s): Takayuki Matsumoto, Takayuki Nagano, Kumiko Taguchi, Tsuneo Kobayashi, Naoko Tanaka-Totoribe
- Pixantrone as a novel MCM2 inhibitor for ovarian cancer treatment
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Abstract: Publication date: Available online 19 July 2024Source: European Journal of PharmacologyAuthor(s): Qingshan Chen, Yaoqi Sun, Hao Li, Shupeng Liu, Hai Zhang, Zhongping Cheng, Yu Wang
- The effect of unliganded gating on agonist response in nicotinic receptors
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Abstract: Publication date: Available online 19 July 2024Source: European Journal of PharmacologyAuthor(s): Dinesh C. Indurthi
- CE9A215 (inotodiol), a lanostane-type oxysterol, mitigates LPS-induced
sepsis through multifaceted mechanisms-
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Abstract: Publication date: Available online 19 July 2024Source: European Journal of PharmacologyAuthor(s): Thi Minh Nguyet Nguyen, Hyunah Park, Thi Thuong Do, Ji-Yun Kwak, Chang-kyu Lee, Seung Hoon Lee, Jong-Il Park, Sun-Young Yoon, Hyunjung Kim, Jihyun Park, Jong-Tae Park
- Experimental models of Parkinson’s disease: Challenges and
Opportunities-
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Abstract: Publication date: Available online 18 July 2024Source: European Journal of PharmacologyAuthor(s): Roshan Lal, Aditi singh, Shivam watts, Kanwaljit Chopra
- The Role of the Gut Microbiome in Neuroinflammation and
Chemotherapy-Induced Peripheral Neuropathy-
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Abstract: Publication date: Available online 18 July 2024Source: European Journal of PharmacologyAuthor(s): Svetlana Shatunova, Rubina Aktar, Madusha Peiris, Jia Yu Peppermint Lee, Irina Vetter, Hana Starobova
- Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1
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Abstract: Publication date: Available online 18 July 2024Source: European Journal of PharmacologyAuthor(s): Xin Ren, Ya Wen, Mu Yuan, Chang Li, Jiejie Zhang, Siyu Li, Xiaowei Zhang, Liang Wang, Shan Wang
- Spermidine as an epigenetic regulator of autophagy in neurodegenerative
disorders-
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Abstract: Publication date: Available online 18 July 2024Source: European Journal of PharmacologyAuthor(s): Sairaj Satarker, Joel Wilson, Kiran Kumar Kolathur, Jayesh Mudgal, Shaila A. Lewis, Devinder Arora, Madhavan Nampoothiri
- BACLOFEN PREVENTS MORPHINE REWARDING EFFECTS AND ASSOCIATED BIOCHEMICAL
ALTERATIONS IN MALE AND FEMALE MICE-
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Abstract: Publication date: Available online 11 July 2024Source: European Journal of PharmacologyAuthor(s): Valeria T. Pedrón, Eliana M. Canero, Andrés P. Varani, Amira J. Aon, Rafael Maldonado, Graciela N. Balerio
- SFN promotes renal fibrosis via binding with MYH9 in chronic kidney
disease-
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Abstract: Publication date: Available online 8 July 2024Source: European Journal of PharmacologyAuthor(s): Fang Wang, Xiao-guo Suo, Jia-nan Wang, Cheng-yi Liu, Cheng-cheng Liu, Cong Wang, Jing Li, Zi-hao Duan, Feng-sen Zhang, Yi-miao Xia, Jun-jie Jiang, Yun-wu Hao, Guang-yuan Li, Xiao-ming Meng, Yun-xia Shao, Fa-cai Wang
- Targeting the RAS upstream and downstream signaling pathway for Cancer
treatment-
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Abstract: Publication date: Available online 10 June 2024Source: European Journal of PharmacologyAuthor(s): Md. Arafat Hossain
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