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- Psychotherapy in the Management of the Upcoming Storm of Post-COVID
Spectrum of Psychological Disorders
Authors: Hima Bindu Ponnam, Butchi Raju Akondi
Pages: 278 - 281
Abstract: No Abstract.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28947
Issue No: Vol. 13, No. 4 (2021)
- Knowledge Attitude and Practices of Patients Attending a Private Dental
Hospital on Miswak
Authors: Shanthi Vanka, Renad Otaif, Samar Salah Hassan, Hanan Abdul Almajeed Alhashdi, Eman Ali Alzahrani, Othman Wali, Amit Vanka, Sajda Khan Gajdhar
Pages: 282 - 287
Abstract: Today, chewing sticks are being used commonly in the world. They are known by various names, including Miswak or arak in Arabic. The efficacy of Miswak and modern toothbrushes have shown a superior effect rather than use of toothbrush alone. This study aims to assess the Knowledge Attitude and Practices of patients attending a private dental hospital on Miswak. This is a cross-sectional analytical study. The study was conducted by means of a questionnaire, in order to obtain knowledge, attitude and practices of patients attending a private dental hospital on Miswak. An electronic copy of the questionnaire was prepared using Google forms in Arabic and distributed through social media. There were 342 respondents for the survey. About 93% of the participants selected that they use any oral hygiene aid as it is beneficial. Among all the participants only 2.3% of them used Miswak as an oral hygiene aid and 31.6% used both tooth brush and paste and Miswak. Majority of the respondents cleaned their teeth twice or thrice in a day. One of the main reasons of using Miswak by the participants was its religious background. The respondents prefer that the next generation would use a combination of Miswak and tooth brush.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28202
Issue No: Vol. 13, No. 4 (2021)
- The Effect of Patient Education Interventions on Asthma Management in Hail
Region
Authors: Bayan Mesar Alanazi, Hala Salem Alshammari, Noyer Eid Alshammari, Khatoon Al Ghazwi, Nasrin E. Khalifa, Marwa Helmy Abdallah, Naifah Assaf Alshameri, Weiam Hussein, Farhan Alshammari
Pages: 288 - 293
Abstract: The rising importance of educating asthma patients about their medication and devices and how to use them and the impact of this knowledge on controlling the disease and improving the quality of life has attracted great interest from researchers in assessing the current situation of dealing with the disease in their community. The purpose of this study is therefore to assess the knowledge of asthma patients about their medication and devices, highlight the problems in the advice provided by health-care providers to asthma patients and study the potential impact of education on the management of asthma. The study was also designed to encourage health-care providers to provide appropriate education for patients and develop an educational program for the management of asthma. A cross-sectional study was conducted using two types of questionnaire, the first directed at asthmatic patients to assess their knowledge and the other directed at health-care providers to assess the challenges, which they faced in advising patients. The results showed that patients’ awareness of asthma was of a medium level. Moreover, the level of challenges faced by health-care providers when advising patients to teach them how to use asthma medications and devices was also of a medium level. The most significant problems were time and lack of patient interest. The findings explained that asthmatic patients in Hail region need improvement in their level of awareness about the use of asthma medications and devices in order to achieve a higher degree of disease control, which will be achieved through the development and implementation of an educational program by health-care providers.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28546
Issue No: Vol. 13, No. 4 (2021)
- Disadvantages of using Traditional, Interactive and Distance Learning
Methods when Studying the Specialty "Pharmacy"
Authors: Mariia Sergeevna Soboleva
Pages: 294 - 299
Abstract: Interactive and remote technologies are being actively introduced into the training process in the specialty “Pharmacy.” In addition to ease of use, they have several advantages and disadvantages for all stakeholders. The purpose of the work is to analyze the disadvantages of traditional, interactive, and remote methods of teaching in the specialty “Pharmacy” at the Far Eastern State Medical University. This is a sociological survey of students of the Faculty of Pharmacy and Biomedicine (higher education), as well as the Medical-Pharmaceutical College (secondary education). Statistical processing was performed using the non-parametric Mann-Whitney, Kruskal–Wallis, Spearman’s rank correlation coefficient. Traditional teaching methods are characterized by the inconvenience of tight time frames. During on-line classes, it is more difficult to use an individual methodology for the student and change the teaching method. The most characteristic shortcomings of distance learning include the lack of motivation and the possibility of violations (writing off, forgery, etc.) by the student. Despite the geographical remoteness of the regions, material, and technical difficulties in switching to distance learning, as a rule, did not arise. The lack of an individual approach and the subjectivity of student assessments in distance and traditional teaching methods are due to the high occupancy of groups and their frequent combination (10-25 people) during the class. The disadvantage of remote methods is the complexity of regular control by the teacher, the lack of secure personality identification systems when sending written works and testing on-line, and the low level of consciousness of future specialists. According to the results of the questionnaire, the least number of shortcomings have interactive teaching methods, implying the active participation of the student himself and an individual approach.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28090
Issue No: Vol. 13, No. 4 (2021)
- A Pilot Study for Gender Variation and Correlation of Anthropometric
Parameters on the Variables of Brainstem Auditory Evoked Potentials in
Audiometrically Normal Young Adults
Authors: Anupinder Thind, Ravdeep Singh, Avnish Kumar, Puneet Gambhir
Pages: 300 - 311
Abstract: Head size gender and BMI have found to have correlation with Brainstem Auditory Evoked Potentials (BAEPs) in some studies but other have expressed doubts. There is no common consensus. To add to the complexity, the range of normative values also vary. The present pilot study was done aiming to study effect of gender and anthropometric parameters on the variables of BAEPs in audiometrically normal young adults and collect normative values for further studies. This was an observational prospective, cross sectional, pilot study conducted among 100 medical students with 50 males and 50 females. The selected students fulfilled the inclusion and exclusion criteria and had given informed consent for the study. In the study RMS EMG EP MARK II machine was used to measure and record the absolute, interpeak and wave amplitudes. The data was collected and statistically analysed. The BAEP measurements from the subjects were compared with gender and anthropometric measurements. The age of students enrolled in subject ranged from 18–21 years. The difference between Left and Right ears Wave I, III and V, besides I-Ia and V-Va difference was found to be significant; while differences between male and female peak latencies of Wave III (left and right) and V (left and right) and Wave IV right ear, I-V IPL and V-Va of Right ear were found to be statistically significant. BMI did not show any statistically significant correlation with BAEPs. AEP results were definitely individual effected by gender, with latency duration more among males than females in most BAERs but were significant in few. The head circumference of a person appears to affect the BAER. BMI in the study was not significant with BAER variables.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28296
Issue No: Vol. 13, No. 4 (2021)
- Comparative Study for Prediction of Low and High Plasma Protein Binding
Drugs by Various Machine Learning-Based Classification Algorithms
Authors: Sumit Govil, Sandesh Tripathi, Amit Kumar, Divya Shrivastava, Shailesh Kumar
Pages: 312 - 320
Abstract: In the drug discovery path, most drug candidates failed at the early stages due to their pharmacokinetic behavior in the system. Early prediction of pharmacokinetic properties and screening methods can reduce the time and investment for lead discoveries. Plasma protein binding is one of these properties which has a vital role in drug discovery and development. The focus of the current study is to develop a computational model for the classification of Low Plasma Protein Binding (LPPB) and High Plasma Protein Binding (HPPB) drugs using machine learning methods for early screening of molecules through WEKA. Plasma protein binding drugs data was collated from the Drug Bank database where 617 drug candidates were found to interact with plasma proteins, out of which an equal proportion of high and low plasma protein binding drugs were extracted to build a training set of ~300 drugs. The machine learning algorithms were trained with a training set and evaluated by a test set. We also compared various machine learning-based classification algorithms i.e., the Naïve Bayes algorithm, Instance-Based Learner (IBK), multilayer perceptron, and random forest to determine the best model based on accuracy. It was observed that the random forest algorithm-based model outperforms with an accuracy of 99.67% and 0.9933 kappa value on training set and on test set as compared to other classification methods and can predict drug plasma binding capacity in the given data set using the WEKA tool.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28497
Issue No: Vol. 13, No. 4 (2021)
- Role of NMDA Receptors in Alzheimer's Disease Pathology and Potential
NMDA Receptor Blockers from Medicinal Plants - A Review
Authors: N.V. Prasanth, P. Pandian, T. Balasubramanian
Pages: 321 - 326
Abstract: Alzheimer’s disease is responsible for 60-70 percent of dementia cases worldwide. Globally, there are 24.3 million cases. Researchers have attempted to develop multi-target medications to suppress several mechanisms in Alzheimer’ Disease, like protein mis-folding and related beta amyloid aggregation, oxidative stress, and decreasing Acetyl choline levels. NMDA-mediated neurotoxicity is often linked to cognitive impairment, as shown in Alzheimer’s disease. NMDA receptors found to have to connection with beta amyloid peptide and tau protein deposition which are major characteristics of Alzheimer’s disease. NMDA receptor antagonists are a viable therapy option for a many neurological disorders, as well as Alzheimer’s disease. Currently, majority of the drugs used in the management of Alzheimer’s disease are Acetyl choline Esterase inhibitors. Memantine is the only approved NMDA blocker, to be used in Alzheimer’s disease, which is found to be effective only to a certain extend. There is a need for better therapeutic agents belonging to this class. This paper intends to provide a rapid reference about the involvement of NMDA receptors in the pathogenesis of Alzheimer’s disease, as well as phyto constituents that have been identified to inhibit NMDA receptors.
PubDate: 2021-12-21
DOI: 10.18311/ajprhc/2021/28351
Issue No: Vol. 13, No. 4 (2021)
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