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  Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
Showing 401 - 253 of 253 Journals sorted alphabetically
Microbial Drug Resistance     Hybrid Journal   (Followers: 3)
Molecular Informatics     Hybrid Journal   (Followers: 5)
Molecular Pharmacology     Hybrid Journal   (Followers: 2)
Molekul     Open Access   (Followers: 1)
Natural Product Communications     Open Access  
Nature Reviews Drug Discovery     Full-text available via subscription   (Followers: 318)
Naunyn-Schmiedeberg's Archives of Pharmacology     Hybrid Journal  
NeuroMolecular Medicine     Hybrid Journal  
Neuropharmacology     Hybrid Journal   (Followers: 6)
Neuropsychopharmacology     Hybrid Journal   (Followers: 18)
Neuropsychopharmacology Reports     Open Access  
Nigerian Journal of Natural Products and Medicine     Full-text available via subscription  
OA Drug Design & Delivery     Open Access  
OA Medical Hypothesis     Open Access  
Obesity Facts     Open Access   (Followers: 8)
Open Pharmacoeconomics & Health Economics Journal     Open Access  
Open Pharmacology Journal     Open Access  
OpenNano     Open Access   (Followers: 1)
Orbital - The Electronic Journal of Chemistry     Open Access   (Followers: 1)
Oriental Pharmacy and Experimental Medicine     Partially Free   (Followers: 2)
Pain and Therapy     Open Access   (Followers: 3)
Particulate Science and Technology: An International Journal     Hybrid Journal   (Followers: 1)
PDA Journal of Pharmaceutical Science and Technology     Full-text available via subscription   (Followers: 36)
Pediatric Drugs     Full-text available via subscription   (Followers: 4)
Pediatric Pharmacology     Open Access   (Followers: 1)
Pharmaceutica Analytica Acta     Open Access  
Pharmaceutical Biology     Open Access  
Pharmaceutical Care-La Farmacoterapia     Open Access  
Pharmaceutical Chemistry Journal     Hybrid Journal  
Pharmaceutical Development and Technology     Hybrid Journal   (Followers: 21)
Pharmaceutical Executive     Full-text available via subscription   (Followers: 6)
Pharmaceutical Fronts     Open Access   (Followers: 6)
Pharmaceutical Historian     Open Access  
Pharmaceutical Journal     Free   (Followers: 8)
Pharmaceutical Journal of Sri Lanka     Open Access  
Pharmaceutical Medicine     Full-text available via subscription   (Followers: 4)
Pharmaceutical Nanotechnology     Hybrid Journal  
Pharmaceutical Patent Analyst     Full-text available via subscription   (Followers: 3)
Pharmaceutical Research     Hybrid Journal   (Followers: 97)
Pharmaceutical Statistics     Hybrid Journal   (Followers: 16)
Pharmaceutical Technology     Full-text available via subscription   (Followers: 6)
Pharmaceuticals     Open Access   (Followers: 4)
Pharmacia     Open Access  
PharmacoEconomics     Full-text available via subscription   (Followers: 26)
PharmacoEconomics & Outcomes News     Full-text available via subscription   (Followers: 4)
PharmacoEconomics German Research Articles     Full-text available via subscription  
PharmacoEconomics Spanish Research Articles     Hybrid Journal   (Followers: 1)
Pharmacoepidemiology and Drug Safety     Hybrid Journal   (Followers: 34)
Pharmacogenetics and Genomics     Hybrid Journal   (Followers: 1)
Pharmacogenomics     Hybrid Journal   (Followers: 7)
Pharmacogenomics and Personalized Medicine     Open Access   (Followers: 2)
Pharmacogenomics Journal     Hybrid Journal   (Followers: 5)
Pharmacognosy Communications     Partially Free  
Pharmacognosy Magazine     Open Access   (Followers: 2)
Pharmacognosy Research     Open Access   (Followers: 2)
Pharmacological Reports     Hybrid Journal  
Pharmacological Research     Hybrid Journal   (Followers: 1)
Pharmacological Research - Modern Chinese Medicine     Open Access  
Pharmacological Reviews     Hybrid Journal   (Followers: 2)
Pharmacology     Full-text available via subscription  
Pharmacology & Therapeutics     Hybrid Journal   (Followers: 3)
Pharmacology & Pharmacy     Open Access   (Followers: 1)
Pharmacology Biochemistry and Behavior     Hybrid Journal   (Followers: 2)
Pharmacology Research & Perspectives     Open Access  
Pharmacon : Jurnal Farmasi Indonesia     Open Access  
Pharmacopsychiatry     Hybrid Journal   (Followers: 3)
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy     Hybrid Journal   (Followers: 38)
Pharmactuel     Open Access   (Followers: 1)
Pharmacy     Open Access   (Followers: 4)
Pharmacy & Pharmacology     Open Access  
Pharmacy Education     Full-text available via subscription   (Followers: 11)
Pharmacy Practice (Internet)     Open Access   (Followers: 8)
Pharmakon : Arzneimittel in Wissenschaft und Praxis     Full-text available via subscription   (Followers: 1)
PharmaNutrition     Hybrid Journal   (Followers: 3)
PharmaTutor     Open Access  
Pharmazeutische Industrie     Full-text available via subscription   (Followers: 11)
Pharmazeutische Zeitung     Full-text available via subscription   (Followers: 15)
Pharmazie in Unserer Zeit (Pharmuz)     Hybrid Journal   (Followers: 18)
Physiology International     Full-text available via subscription   (Followers: 3)
Plant Products Research Journal     Full-text available via subscription  
Planta Medica     Hybrid Journal   (Followers: 4)
Planta Medica International Open     Open Access  
Prescriber     Hybrid Journal   (Followers: 9)
Progress in Neuro-Psychopharmacology and Biological Psychiatry     Hybrid Journal   (Followers: 8)
Psychiatry and Clinical Psychopharmacology     Open Access   (Followers: 1)
Psychopharmacology     Hybrid Journal   (Followers: 16)
Pulmonary Pharmacology & Therapeutics     Hybrid Journal   (Followers: 2)
PZ Prisma : Materialien zur Fort- und Weiterbildung     Full-text available via subscription  
Redox Report     Open Access  
Regulatory Mechanisms in Biosystems     Open Access   (Followers: 1)
Regulatory Toxicology and Pharmacology     Hybrid Journal   (Followers: 41)
Research & Reviews : A Journal of Drug Design & Discovery     Full-text available via subscription  
Research & Reviews : A Journal of Pharmaceutical Science     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacognosy     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacology     Full-text available via subscription   (Followers: 1)
Research in Pharmaceutical Sciences     Open Access   (Followers: 3)
Research in Social and Administrative Pharmacy     Hybrid Journal   (Followers: 3)
Research Journal of Pharmacognosy     Open Access  
Research Results in Pharmacology     Open Access  
Reviews of Physiology, Biochemistry and Pharmacology     Hybrid Journal   (Followers: 4)
Reviews on Clinical Pharmacology and Drug Therapy     Full-text available via subscription  
Revista Colombiana de Ciencias Químico-Farmacéuticas     Open Access  
Revista Cubana de Plantas Medicinales     Open Access   (Followers: 1)
Revista de Ciências Farmacêuticas Básica e Aplicada     Open Access  
Revista Mexicana de Ciencias Farmaceuticas     Open Access  
Revue de Médecine et de Pharmacie     Full-text available via subscription  
Safety and Risk of Pharmacotherapy     Open Access   (Followers: 1)
Saudi Pharmaceutical Journal     Open Access  
Scandinavian Journal of Clinical and Laboratory Investigation     Hybrid Journal   (Followers: 8)
Scientia Pharmaceutica     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Oncology Nursing     Full-text available via subscription   (Followers: 10)
Separation Science plus (SSC plus)     Hybrid Journal  
Side Effects of Drugs Annual     Full-text available via subscription   (Followers: 2)
Skin Pharmacology and Physiology     Full-text available via subscription   (Followers: 6)
Substance Abuse : Research and Treatment     Open Access   (Followers: 5)
Suchttherapie     Hybrid Journal   (Followers: 1)
Sustainable Chemistry and Pharmacy     Full-text available via subscription   (Followers: 1)
Synfacts     Hybrid Journal   (Followers: 5)
SynOpen     Open Access  
The Botulinum J.     Hybrid Journal  
The Brown University Psychopharmacology Update     Hybrid Journal   (Followers: 2)
The Medical Letter     Full-text available via subscription   (Followers: 18)
The Pink Sheet     Full-text available via subscription   (Followers: 12)
The Pink Sheet Daily     Full-text available via subscription   (Followers: 5)
Therapeutic Advances in Drug Safety     Open Access   (Followers: 3)
Therapeutic Advances in Psychopharmacology     Open Access   (Followers: 4)
Therapeutic Advances in Vaccines     Hybrid Journal   (Followers: 1)
Therapeutic Drug Monitoring     Hybrid Journal   (Followers: 5)
Therapeutic Innovation & Regulatory Science     Hybrid Journal   (Followers: 7)
Thérapie     Full-text available via subscription   (Followers: 1)
TheScientist     Free   (Followers: 6)
Toxicological & Environmental Chemistry     Hybrid Journal   (Followers: 2)
Toxicological Research     Hybrid Journal  
Toxicological Sciences     Hybrid Journal   (Followers: 11)
Toxicology     Hybrid Journal   (Followers: 19)
Toxicology and Applied Pharmacology     Hybrid Journal   (Followers: 25)
Toxicology and Industrial Health     Hybrid Journal   (Followers: 6)
Toxicology in Vitro     Hybrid Journal   (Followers: 12)
Toxicology International     Full-text available via subscription   (Followers: 5)
Toxicology Letters     Hybrid Journal   (Followers: 16)
Toxicology Mechanisms and Methods     Hybrid Journal   (Followers: 9)
Toxicology Research     Partially Free   (Followers: 8)
Toxicon     Hybrid Journal   (Followers: 5)
Toxicon : X     Open Access  
Toxin Reviews     Hybrid Journal  
Translational Psychiatry     Open Access   (Followers: 14)
Trends in Peptide and Protein Sciences     Open Access  
Trends in Pharmacological Sciences     Full-text available via subscription   (Followers: 21)
Tropical Journal of Pharmaceutical Research     Open Access  
Ukrainian Biopharmaceutical Journal     Open Access  
Vascular Pharmacology     Hybrid Journal   (Followers: 2)
World Mycotoxin Journal     Hybrid Journal   (Followers: 3)
Yakugaku Zasshi     Open Access   (Followers: 1)
Zeitschrift für Phytotherapie     Hybrid Journal   (Followers: 1)
Актуальні питання фармацевтичної та медичної науки та практики     Open Access  
Фармацевтичний часопис     Open Access  

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Plant Products Research Journal
Number of Followers: 0  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1119-2283
Published by African Journals Online Homepage  [261 journals]
  • Preliminary evaluation of the synergistic effects of methanol extracts of
           garlic and some conventional antimicrobial agents on bacterial isolates
           from HVS

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      Authors: CI Nnamchi, IB Nwosa
      Abstract: The emergence of multiple drug resistant organisms has made the treatment combinations of conventional drugs with medicinal plants against resistant microorganisms necessary. Therefore, this work aimed to discover how the potency of some conventional antimicrobial drugs can be increased by combining them with the natural antimicrobial potentials of garlic. This was carried out using ethanolic extracts of garlic in combination with the drugs against clinical bacterial isolates obtained from high vaginal swab (HVS) using the agar overlay inoculum susceptibility disc method. A total of 24 clinical bacterial isolates obtained after successive sub-culturing were tested against the antibiotics alone and after their combinations with garlic extracts. The number of the clinical isolates reduced upon identification to just six different bacterial species: Escherichia coli, Enterococcus sp., Staphylococcus aureus, Enterobacter sp., Citrobacter sp. and Klebsiella sp. Result obtained showed that when only antibiotic sensitivity discs alone was used, the isolates showed resistance to them in varying degrees. For example, isolate 2B, a Citrobacter sp. showed resistance to 9 of the 10 antibiotics, followed by isolate 4, Klebsiella sp. which resisted 8 antibiotics and isolates 3 (Escherichia coli) and 7 (Enterobacter sp.) which resisted 5 antibiotics each. In terms of antibiotics, resistance was shown most to nitrofurantoin, with 16 out the 24 isolates resisting it and ampicillin, 12 isolates. However, combinations of the antibiotics with methanolic extracts of garlic reduced the incidence of resistance to significant levels, reaching 100% reductions in resistance in many cases. Thus the use of garlic extract in combinations with antibiotics positively increased the killing abilities of most of them. These are clearly positive results that should be adequately exploited for humanity’s benefit.
      Key words: Antibiotics, garlic, extract, synergism, resistance, antagonism.
      PubDate: 2013-12-03
      Issue No: Vol. 16, No. 1 (2013)
       
  • Tolerance study of aqueous extract of Mitracarpus
           scaber
    in rabbits

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      Authors: D Idrissa, O Karamoko, CA Founzegue, Y Felix, AJ Djaman, JD N'guessan
      Abstract: The study was to evaluate the cardiac safety of Mitracarpus scaber  (Rubiaceae) in rabbit. In this study, different batches of rabbits were injected with increasing doses of aqueous extract of Mitracarpus scaber (encoded) and changes in the activities of serum glutamic oxaloacetic transaminase (GOT), lactate deshydrogenase (LDH) and creatine phosphokinase (CPK) measured. The statistical analysis of the serum activities of these enzymes indicate a significant variation (P<0.05) of the serum activity of CPK and LDH. But there is no significant change of serum activity of GOT (P>0.05). In conclusion, the aqueous extract of Misca at dose of 100 mg/kg body weight for 4 weeks induces no cardiac dysfunction and is therefore well tolerated by the heart.
      Key words: Mitracarpus scaber, heart, GOT, LDH, CPK.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Evaluation of plasma electrolyte concentration in pregnant Nigerian women
           from Edo State, Nigeria

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      Authors: EC Onyeneke, AI Anekwe, SJ Okoro, JC Anionye, OE Onovughakpo-Sakpa
      Abstract: The renal function status in relation to electrolyte homeostasis was  evaluated in a total of one hundred pregnant Nigerian women (volunteers) and thirty non-pregnant controls. The volunteers were of varying maternal age, parity, trimester, weight, height, and social status while the  non-pregnant women were of approximate age to serve as control. Analysis of the results revealed that sodium (136.21±0.39mmol/l), potassium (3.69±0.004mmol/l), calcium (2.17 ± 0.02mmol/l), and bicarbonate (20.39 ± 0.26mmol/l) were significantly reduced (P<0.05) when compared to the control (137.97±0.46mmol/l, 4.29±0.09mmol/l, 2.59±0.03mmol/l and 25.87±0.43mmol/l respectively). There was a significant decrease (P<0.05) in sodium, potassium, calcium and  bicarbonate concentrations as pregnancy progressed. Maternal age is positively correlated with sodium (r=0.092) and potassium (r=0.100) but inversely correlated with calcium (r=-0.088) and bicarbonate (r=-0.051) concentrations. While parity is inversely correlated with sodium (r=-0.045), potassium (r=-0.155) and calcium (r=-0.175), it was positively correlated with bicarbonate (r=0.015) concentrations. All the electrolytes have positive correlation with gestation (Na+: r=0.249, K+: r=0.204, Ca2+: r=0.004 and HCO3-: r=0.056) while social status was inversely correlated to all the parameters (Na+: r=-0.151, K+: r=-0.075, Ca2+: r=-0.046 and HCO3-: r=0.023;P<0.05). Nutrition, environmental condition and child’s spacing may have influenced the parameters and their implications with respect to proper fetal development are discussed.Key words: Pregnancy, electrolytes.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Comparative effect of Arachis hypogaea and Cajanus cajan diets on the
           lipid profile of female albino rats

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      Authors: AC Nwaka, HA Okeke
      Abstract: The effect of Arachis hypogaea and Cajanus cajan diets on the serum lipid profile of 30 female albino rats were evaluated. The rats were separated into 5 groups of six rats each as follows: A- rats fed on normal feed, B – rats fed on 50% Arachis hypogaea diet, C- rats fed on 70% Arachis  hypogaea, D - rats fed on 50% Cajanus cajan diet and E- rats fed on 70% Cajanus cajan. The study lasted for 28 days and at the end of the feeding experiment, the rats were bled and serum obtained used for total cholesterol, LDL, HDL, triacylglycerol and VLDL assays using standard biochemical methods. The results of the study showed significant decrease (P<0.05) in total cholesterol, VLDL, LDL and triacylglycerol concentrations of rats feds on Cajanus cajan (groups D and E) when compared to those of the control (group A) and those fed on Arachis hypogaea diet (groups B and C). However, there was no significant difference (P>0.05) observed in the HDL levels of rats fed on Cajanus cajan and those of control (group A) and those fed on Arachis hypogaea diet. Results of the study suggest that Cajanus cajan diet could be useful in protecting against atherosclerosis and its associated diseases.
      Key words: Atherosclerosis, Cajanus cajan, Arachis hypogaea and Lipid Profile.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • In vivo antioxidant and antihyperglycaemic properties of aqueous extract
           of herbal cocktail

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      Authors: VN Ogugua, SI Egba, JE Adoga
      Abstract: The antioxidant and antihyperglycamic effects of herbal cocktail namely: Vernonia amygdalina, Gongronema latifolium, Allium sativium, Ocimum gratissmun and Aloe barbadensis were studied on alloxan-induced diabetic rat. Twenty (20) albino Wistar rats were equally divided into five groups. Groups 1 and 2 served as normal and untreated Diabetic controls. Test groups 3, 4 and 5 were treated with 10mg/kg glibenclamide, 200mg and 400mg/kg of extract for 28 days. The result showed a dose dependant significant increase (P<0.05) in serum concentrations of vitamin C, glutathione and catalase activity in test groups when compared to untreated diabetic control. Similarly, the extract significantly reduced (P<0.05) glucose concentration of diabetic rats at both concentrations when compared to untreated diabetic Rats. The results confirmed the already established use of these plants in traditional medicine and equally established their useful synergistic effect in reducing blood sugar and in relieving oxidant stress.
      Key words: Antioxidant, catalase, glutathione, alloxan, antihyperglycaemia
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Production and properties of fungal cellulase from native isolates using
           orange bagasse as carbon source

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      Authors: VA Ogwuche, FC Chilaka, SOO Eze, CU Anyanwu
      Abstract: Orange bagasse was employed as the sole carbon source for production of cellulase having adapted the organisms on cellulose and on orange bagasse. The extracellular cellulase produced by Aspergillus niger and Rhizopus species were partially purified by ammonium sulphate precipitation in a single step and dialyzed. Cellulase activity of partially purified cellulase from Aspergillus niger and Rhizopus species were determined. Cellulase from both fungi had optimum temperature at 45°C but different pH optima of pH 7 and 6.5 respectively. Thermo stability study of the partially purified cellulases carried out over a temperature range of 35°C -70°C show that the enzymes lost stability with increasing temperature. Carboxymethylcellulase (CMCase) and Filter paper unit (FPU) activities of the partially purified cellulase show a higher specific activity for cellulase from Aspergillus niger than that from Rhizopus species.
      Key words: Cellulase, CMCase, Aspergillus niger, Orange bagasse
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Kidney function status in Nigerian human malaria patients

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      Authors: JC Anionye, EC Onyeneke, OE Onovughakpo-Sakpa, AI Anekwe
      Abstract: Malaria is now known to affect over 500 million persons worldwide, killing about 1 to 3 million of them annually. Plasmodium falciparum is the  species mostly implicated in the causation of severe malaria. This study was carried out to investigate the kidney function status of malaria  patients in Benin metropolis, Southern Nigeria, to ascertain if there is renal dysfunction/impairment in them. Plasma levels of sodium, potassium, bicarbonate, urea, creatinine and blood urea nitrogen (BUN) were assayed in a total of 152 subjects (112 malaria patients infected with Plasmodium falciparum and 40 controls) of both sexes, with their age ranging from 8 to 42 years. The results observed irrespective of age or sex, reveal a  statistically significant (p<0.05) increase in plasma levels of potassium, urea, BUN and creatinine (4.49±0.95 mmol/L;5.88±0.13mmol /L;16.39±0.36mg/dl and 135.05±2.69ìmol/L) when compared to their controls (4.05±0.34mmol/L;3.73±0.12mmol/L;10.34±0.36mg/dl and 80.71±1.69ìmol/L, respectively) and also a statistically significant (P<0.05) reduction in plasma levels of Na+ and HC03- (128.50±0.77 and  19.98±0.28mmol/L) when compared to their controls (l38.58±0.29 and 24.70±0.36mmol/L, respectively). The hyponatraemia and metabolic acidosis observed in the malaria patients are negatively correlated with the degree of parasitaemia (r=-0.241 and r=-0.019, respectively), while the elevated plasma potassium and creatinine levels are positively correlated with the degree of parasitaemia (r=0.153 and r=0.407, respectively). The elevated plasma Urea and BUN levels are also positively correlated with the degree of parasitaemia (r=0.371 and r=0.375, respectively). The results of this study indicate that there is significant renal dysfunction/impairment in patients in southern Nigeria infected with plasmodium falciparum.
      Key words: Malaria infection, Kidney function status.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Explant age, auxin concentrations and media type affect callus production
           from oil palm (Elaeis guineensis) embryo axes

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      Authors: HO Shittu, GC Mgbeze, O Asemota, GE Okoloko
      Abstract: The effects of explant age of oil palm (Elaeis huineensis) embryo axes, 15 and 18 weeks after anthesis (WAA), media type (Eeuwens and Murashige and Skoog) supplemented with various concentrations of 2,4-D on callus production employing standard in vitro techniques were investigated. The results of the study showed that the type of response, time of initiation of callus, percentage germinating explants or percentage callusing explants were greatly affected by the age of explants, the concentrations of the growth regulator and type of media. It was found that callus generation was best in the 18 WAA embryo axes culture in Eeuwens’ medium supplemented with 2,4-D. The optimum concentration of the hormone was found to be 50 mgl-1 which initiated callus within 35 days in culture. The percentage callusing explants was 80%.
      Key words: In vitro, callus, explant, auxin, culture, embryo axes.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
  • Production and characterization of pectinases obtained from Aspergillus
           fumigatus in submerged fermentation system using pectin extracted from
           mango peels as carbon source

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      Authors: AL Ezugwu, SOO Eze, FC Chilaka, CU Anyanwu
      Abstract: Pectinase was obtained from Aspergillus fumigatus in a submerged  fermentation system using pectin extracted mango peels as a carbon source and subjected to a two step purification system of 80% ammonium sulphate saturation and dialysis. Pectin was also extracted from mango peels and its extraction yield was found to be 17% at pH 2.2, temperature of 70¢ªC and extraction time of 1h. The protein concentration in the crude enzyme was found to be 1.372mg/ml. The specific activity of crude  enzyme is 11.20¥ìmole/min/mg. After 80% ammonium sulphate  precipitation and dialysis, the specific activities were 11.78¥ìmole/min/mg and 34.60¥ìmole/min/mg respectively. The maximal activity of A. fumigatus pectinase was at 40¢ªC, pH 5.5 and was heat stable up to 40¢ªC.Vmax and Km values were found to be of 625¥ìmole/min and 45.5mg/ml respectively. The pectinase was used to degrade pectins extracted from orange and pineapple peels and its specific activities were found to be 30U/mg and 28.39U/mg respectively as compared to 34.60U/mg which is the specific activity obtained when pectin extracted from dry mango peels was used.
      Key words: Mango peels, pectinase, pectin, Aspergillu fumigatus, submerged fermentation.
      PubDate: 2013-12-02
      Issue No: Vol. 16, No. 1 (2013)
       
 
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