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  Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
Showing 1 - 200 of 253 Journals sorted alphabetically
AAPS Journal     Hybrid Journal   (Followers: 31)
AAPS Open     Open Access   (Followers: 5)
AAPS PharmSciTech     Hybrid Journal   (Followers: 6)
AboutOpen     Open Access  
ACS Pharmacology & Translational Science     Hybrid Journal   (Followers: 5)
Acta Pharmaceutica     Open Access   (Followers: 4)
Acta Pharmaceutica Indonesia     Open Access  
Acta Pharmaceutica Sinica B     Open Access   (Followers: 1)
Acta Pharmacologica Sinica     Hybrid Journal   (Followers: 3)
Acta Physiologica Hungarica     Full-text available via subscription  
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 4)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 98)
Advanced Herbal Medicine     Open Access   (Followers: 9)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Medical, Pharmaceutical and Dental Research     Open Access   (Followers: 5)
Advances in Pharmacoepidemiology & Drug Safety     Open Access   (Followers: 3)
Advances in Pharmacological and Pharmaceutical Sciences     Open Access   (Followers: 11)
Advances in Pharmacology     Full-text available via subscription   (Followers: 21)
Advances in Pharmacology and Pharmacy     Open Access   (Followers: 9)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 4)
Adverse Drug Reaction Bulletin     Full-text available via subscription   (Followers: 5)
AJP : The Australian Journal of Pharmacy     Full-text available via subscription   (Followers: 10)
Al-Azhar Journal of Pharmaceutical Sciences     Open Access   (Followers: 3)
Alternatives to Laboratory Animals     Full-text available via subscription   (Followers: 9)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 20)
American Journal of Drug Discovery and Development     Open Access   (Followers: 3)
American Journal of Health-System Pharmacy     Full-text available via subscription   (Followers: 59)
American Journal of Pharmacological Sciences     Open Access   (Followers: 2)
American Journal of Pharmacology and Toxicology     Open Access   (Followers: 24)
American Journal of Therapeutics     Hybrid Journal   (Followers: 13)
Analytical Methods     Hybrid Journal   (Followers: 8)
Annales Pharmaceutiques Francaises     Full-text available via subscription  
Annals of Pharmacotherapy     Hybrid Journal   (Followers: 56)
Annual Review of Pharmacology and Toxicology     Full-text available via subscription   (Followers: 38)
Anti-Infective Agents     Hybrid Journal   (Followers: 5)
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 6)
Antibiotics     Open Access   (Followers: 12)
Antibody Therapeutics     Open Access  
Antiviral Chemistry and Chemotherapy     Open Access   (Followers: 1)
Antiviral Research     Hybrid Journal   (Followers: 8)
Applied Clinical Trials     Full-text available via subscription   (Followers: 7)
Archiv der Pharmazie     Hybrid Journal   (Followers: 2)
Archives of Drug Information     Hybrid Journal   (Followers: 4)
Archives of Pharmacal Research     Full-text available via subscription   (Followers: 2)
Archives of Pharmacy and Pharmaceutical Sciences     Open Access   (Followers: 2)
Archives of Razi Institute     Open Access  
Archivos Venezolanos de Farmacología y Terapéutica     Open Access  
Ars Pharmaceutica     Open Access  
Asian Journal of Medical and Pharmaceutical Researches     Open Access  
Asian Journal of Pharmaceutical Research and Health Care     Open Access   (Followers: 2)
Asian Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
Asian Journal of Pharmaceutics     Open Access   (Followers: 1)
Asian Journal of Research in Medical and Pharmaceutical Sciences     Open Access  
ASSAY and Drug Development Technologies     Hybrid Journal   (Followers: 3)
Australian Journal of Herbal Medicine     Full-text available via subscription   (Followers: 4)
Australian Pharmacist     Full-text available via subscription   (Followers: 7)
Autonomic & Autacoid Pharmacology     Hybrid Journal  
Avicenna Journal of Phytomedicine     Open Access   (Followers: 1)
Bangladesh Journal of Pharmacology     Open Access  
Bangladesh Journal of Physiology and Pharmacology     Open Access  
Bangladesh Pharmaceutical Journal     Full-text available via subscription  
Basic & Clinical Pharmacology & Toxicology     Hybrid Journal   (Followers: 15)
Behavioural Pharmacology     Hybrid Journal   (Followers: 2)
Bioanalysis     Full-text available via subscription   (Followers: 11)
Biochemical Pharmacology     Hybrid Journal   (Followers: 10)
BioDrugs     Full-text available via subscription   (Followers: 8)
Biological & Pharmaceutical Bulletin     Full-text available via subscription   (Followers: 3)
Biomarkers in Drug Development     Partially Free   (Followers: 2)
Biomaterials     Hybrid Journal   (Followers: 55)
Biomedical and Environmental Sciences     Full-text available via subscription   (Followers: 2)
Biomedicine & Pharmacotherapy     Full-text available via subscription   (Followers: 2)
Biometrical Journal     Hybrid Journal   (Followers: 9)
Biopharm International     Full-text available via subscription   (Followers: 20)
Biopharmaceutics and Drug Disposition     Hybrid Journal   (Followers: 11)
BMC Pharmacology     Open Access   (Followers: 3)
BMC Pharmacology & Toxicology     Open Access   (Followers: 9)
Brazilian Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
British Journal of Clinical Pharmacology     Hybrid Journal   (Followers: 31)
British Journal of Pharmacology     Hybrid Journal   (Followers: 17)
British Journal of Pharmacy (BJPharm)     Open Access   (Followers: 2)
Bulletin of Faculty of Pharmacy, Cairo University     Open Access   (Followers: 2)
CADTH Technology Overviews     Free  
Canadian Journal of Pain     Open Access   (Followers: 3)
Canadian Journal of Physiology and Pharmacology     Hybrid Journal   (Followers: 2)
Canadian Pharmacists Journal / Revue des Pharmaciens du Canada     Hybrid Journal   (Followers: 3)
Cancer Biotherapy & Radiopharmaceuticals     Hybrid Journal  
Cancer Chemotherapy and Pharmacology     Hybrid Journal   (Followers: 4)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Therapeutics     Open Access   (Followers: 3)
Cephalalgia Reports     Open Access  
Chemical and Pharmaceutical Bulletin     Full-text available via subscription   (Followers: 1)
Chemical Research in Toxicology     Hybrid Journal   (Followers: 22)
ChemMedChem     Hybrid Journal   (Followers: 9)
Chemotherapy     Full-text available via subscription   (Followers: 3)
Chinese Herbal Medicines     Full-text available via subscription   (Followers: 1)
Chinese Journal of Pharmaceutical Analysis     Full-text available via subscription  
Ciencia e Investigación     Open Access  
Ciência Equatorial     Open Access  
Clinical and Experimental Pharmacology and Physiology     Hybrid Journal   (Followers: 7)
Clinical and Translational Science     Open Access   (Followers: 4)
Clinical Complementary Medicine and Pharmacology     Open Access  
Clinical Drug Investigation     Full-text available via subscription   (Followers: 7)
Clinical Medicine Insights : Therapeutics     Open Access  
Clinical Neuropharmacology     Hybrid Journal   (Followers: 2)
Clinical Pharmacist     Partially Free   (Followers: 12)
Clinical Pharmacokinetics     Full-text available via subscription   (Followers: 27)
Clinical Pharmacology & Therapeutics     Hybrid Journal   (Followers: 45)
Clinical Pharmacology in Drug Development     Hybrid Journal   (Followers: 4)
Clinical Pharmacology: Advances and Applications     Open Access   (Followers: 6)
Clinical Research and Regulatory Affairs     Hybrid Journal   (Followers: 9)
Clinical Therapeutics     Hybrid Journal   (Followers: 34)
Clinical Toxicology     Hybrid Journal   (Followers: 18)
Clinical Trials     Hybrid Journal   (Followers: 19)
CNS Drug Reviews     Open Access   (Followers: 4)
CNS Drugs     Full-text available via subscription   (Followers: 10)
Combination Products in Therapy     Open Access  
Consultant Pharmacist     Full-text available via subscription   (Followers: 2)
Consumer Drugs     Full-text available via subscription  
Contract Pharma     Full-text available via subscription  
Cosmetics     Open Access   (Followers: 4)
CPT : Pharmacometrics & Systems Pharmacology     Open Access   (Followers: 11)
Critical Reviews in Clinical Laboratory Sciences     Hybrid Journal   (Followers: 16)
Critical Reviews in Therapeutic Drug Carrier Systems     Full-text available via subscription   (Followers: 5)
Critical Reviews in Toxicology     Hybrid Journal   (Followers: 25)
Current Bioactive Compounds     Hybrid Journal  
Current Cancer Therapy Reviews     Hybrid Journal   (Followers: 5)
Current Clinical Pharmacology     Hybrid Journal   (Followers: 4)
Current Drug Delivery     Hybrid Journal   (Followers: 6)
Current Drug Discovery Technologies     Hybrid Journal   (Followers: 6)
Current Drug Metabolism     Hybrid Journal   (Followers: 5)
Current Drug Safety     Hybrid Journal   (Followers: 9)
Current Drug Targets     Hybrid Journal   (Followers: 4)
Current Drug Therapy     Hybrid Journal   (Followers: 3)
Current Enzyme Inhibition     Hybrid Journal   (Followers: 1)
Current Issues in Pharmacy and Medical Sciences     Open Access   (Followers: 2)
Current Medical Science     Hybrid Journal  
Current Medicinal Chemistry     Hybrid Journal   (Followers: 13)
Current Molecular Pharmacology     Hybrid Journal  
Current Nanoscience     Hybrid Journal  
Current Neuropharmacology     Hybrid Journal   (Followers: 1)
Current Opinion in Pharmacology     Hybrid Journal   (Followers: 9)
Current Pharmaceutical Analysis     Hybrid Journal   (Followers: 1)
Current Pharmaceutical Biotechnology     Hybrid Journal   (Followers: 10)
Current Pharmaceutical Design     Hybrid Journal   (Followers: 12)
Current Pharmacogenomics and Personalized Medicine     Hybrid Journal   (Followers: 3)
Current Pharmacology Reports     Hybrid Journal  
Current Protocols in Pharmacology     Hybrid Journal  
Current Radiopharmaceuticals     Hybrid Journal   (Followers: 1)
Current Research in Drug Discovery     Open Access   (Followers: 2)
Current Research in Pharmacology and Drug Discovery     Open Access   (Followers: 1)
Current Therapeutic Research     Open Access   (Followers: 6)
Current trends in Biotechnology and Pharmacy     Open Access   (Followers: 7)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 4)
Dhaka University Journal of Pharmaceutical Sciences     Open Access  
Die Pharmazie - An International Journal of Pharmaceutical Sciences     Full-text available via subscription   (Followers: 5)
Dose-Response     Open Access  
Drug and Chemical Toxicology     Hybrid Journal   (Followers: 13)
Drug and Therapeutics Bulletin     Hybrid Journal   (Followers: 8)
Drug Delivery     Open Access   (Followers: 8)
Drug Delivery and Translational Research     Hybrid Journal   (Followers: 2)
Drug Design, Development and Therapy     Open Access   (Followers: 3)
Drug Development and Industrial Pharmacy     Hybrid Journal   (Followers: 30)
Drug Development Research     Hybrid Journal   (Followers: 11)
Drug Discovery Today: Technologies     Full-text available via subscription   (Followers: 12)
Drug Metabolism and Disposition     Hybrid Journal   (Followers: 11)
Drug Metabolism and Pharmacokinetics     Hybrid Journal   (Followers: 6)
Drug Metabolism Letters     Hybrid Journal   (Followers: 3)
Drug Metabolism Reviews     Hybrid Journal   (Followers: 8)
Drug Research     Hybrid Journal   (Followers: 3)
Drug Resistance Updates     Hybrid Journal   (Followers: 3)
Drug Safety     Full-text available via subscription   (Followers: 86)
Drug Safety - Case Reports     Open Access   (Followers: 2)
Drug Target Insights     Open Access  
Drug, Healthcare and Patient Safety     Open Access   (Followers: 10)
Drugs     Full-text available via subscription   (Followers: 152)
Drugs & Aging     Full-text available via subscription   (Followers: 10)
Drugs & Therapy Perspectives     Full-text available via subscription   (Followers: 9)
Drugs : Real World Outcomes     Hybrid Journal   (Followers: 1)
Drugs and Therapy Studies     Open Access  
Drugs in R & D     Full-text available via subscription   (Followers: 2)
Drugs of the Future     Full-text available via subscription   (Followers: 7)
East and Central African Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
Egyptian Pharmaceutical Journal     Open Access  
EJNMMI Radiopharmacy and Chemistry     Open Access  
EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei     Full-text available via subscription  
Emerging Trends in Drugs, Addictions, and Health     Open Access   (Followers: 1)
Environmental Toxicology and Pharmacology     Hybrid Journal   (Followers: 9)
Epilepsy Research     Hybrid Journal   (Followers: 7)
Ethiopian Pharmaceutical Journal     Full-text available via subscription   (Followers: 1)
EUREKA : Health Sciences     Open Access  
European Journal of Clinical Pharmacology     Hybrid Journal   (Followers: 14)
European Journal of Drug Metabolism and Pharmacokinetics     Hybrid Journal   (Followers: 8)
European Journal of Hospital Pharmacy : Science and Practice (EJHP)     Hybrid Journal   (Followers: 5)
European Journal of Medicinal Plants     Open Access   (Followers: 2)
European Journal of Pharmaceutical Sciences     Hybrid Journal   (Followers: 89)
European Journal of Pharmaceutics and Biopharmaceutics     Hybrid Journal   (Followers: 35)
European Journal of Pharmacology     Hybrid Journal   (Followers: 8)
European Neuropsychopharmacology     Hybrid Journal   (Followers: 9)
European Review for Medical and Pharmacological Sciences     Full-text available via subscription   (Followers: 1)
Experimental and Clinical Psychopharmacology     Full-text available via subscription   (Followers: 8)

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Dhaka University Journal of Pharmaceutical Sciences
Journal Prestige (SJR): 0.183
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1816-1820 - ISSN (Online) 1816-1839
Published by Bangladesh Journals Online Homepage  [87 journals]
  • Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter

    • Authors: Olufunmilayo Ebunoluwa Adejumo, Temilade Arinola Edun, Adelodun Lawrence Kolapo, Olatunde Adekunle Ayodele
      Pages: 105 - 115
      Abstract: Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p < 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. Similarly, 40% of samples did not qualify for domestic consumption and food industry applications. Hence, the samples with <5% DV values cannot serve as dietary sources of α-tocopherol. Dhaka Univ. J. Pharm. Sci. 21(2): 105-115, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63112
      Issue No: Vol. 21, No. 2 (2022)
  • A Cross-sectional Study to Evaluate People's Knowledge, Attitude and
           Practice Towards Using Disinfectants and Sanitizers During COVID-19
           Pandemic in Bangladesh

    • Authors: Koma Afrin Rintu, Kazi Milenur Rahman Prattay, KM Yasif Kayes Sikdar, Tanvir Rahman, Md Raihan Sarkar, Tanveer Hossain
      Pages: 117 - 126
      Abstract: The devastating novel coronavirus (COVID-19) pandemic worldwide has become a global health crisis. This disease is highly contagious and caused by the transmission of severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2). To prevent the transmission of SARS-CoV-2, disinfectants and sanitizers are very effective and readily available preventive agents. In this study, knowledge, attitude and practice (KAP) levels of Bangladeshi people's were assessed regarding the use of disinfectants and sanitizers during the pandemic. An online questionnaire-based survey was conducted among the respondents from July 2021 to December 2021. A total number of 428 respondents participated in this survey. Data were analysed by the Statistical Package for the Social Sciences (SPSS) V26 software and interpreted. Results revealed that most of the respondents were knowledgeable, had a positive attitude and engaged in beneficial practice. Among the respondents, a significantly higher knowledge and practice score were observed among females (54.1% and 54.4%, respectively) than their counterpart. Moreover, people living in urban areas (71.7%) had a better attitude than the rural people (28.3%). In addition, a medium positive correlation between knowledge and attitude (r = + 0.482), a weak positive association between attitude and practice (r = +0.199), and a weak positive association between knowledge and practice (r = + 0.282) were found. Overall, majority of the respondents had better KAP scores in knowledge and attitude with relatively low scores in practice which indicates some space for betterment. Dhaka Univ. J. Pharm. Sci. 21(2): 117-126, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63113
      Issue No: Vol. 21, No. 2 (2022)
  • Ethnopharmacological Survey of Medicinal Plants Used by Traditional Health
           Practitioners and Indigenous People in Chittagong Hill Tracts, Bangladesh
           for the Treatment of Dysentery

    • Authors: Sajan Das, Shupti Rani Bhadra, Muhammad Shah Mohtasim Khan, Md Mahfuzul Hasan, Md Rafi Anwar, Mohammad Shahriar
      Pages: 127 - 146
      Abstract: Dysentery is frequently associated with high morbidity and mortality and is found in young children and mainly affects those in developing nations. Rural people across the world trust on herbal remedies and homeopathic medicines for their primary health care on account of their easy accessibility, efficacy and exceptionally cost ampleness in relation to modern drugs. The purpose of the present study was to compile knowledge of traditional healers and indigenous people in Chittagong hill tracts, Bangladesh, including Rangamati, Bandarban and Khagrachari for the treatment of dysentery. The ethnomedicinal data was gathered from January 2019 to January 2020 through open and focused group discussions and individual meetings utilizing semi-structured questionnaire. An aggregate of 75 people were interviewed, including traditional health practitioners. Frequency and percentage were utilized to sum up the data. Relative frequency of citation (RFC) was determined and inclination positioning activities were led to appraise the significance of the revealed medicinal plants. An aggregate of 90 medicinal plants from 52 families and 79 genera were recorded during the survey. Leaves were discovered to be the most largely used plant part (35%) followed by root (19%) and herbs (40%) were the essential wellspring of medicinal plants, followed by trees (20%). The major mode of preparation is juice (68%) followed by paste (11%) and cooked form (7%). Centella asiatica scored the highest RFC value (0.773). The survey addresses the preliminary information of certain medicinal plants having anti-dysenteric property. However, further phytochemical investigation, validation and clinical trial sought to be conducted, with need given to those that scored the most elevated RFC values prior to utilizing these plants as an option in contrast to modern medicine. Dhaka Univ. J. Pharm. Sci. 21(2): 127-146, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63114
      Issue No: Vol. 21, No. 2 (2022)
  • Evaluation of Total Phenolic, Flavonoid Content and Antioxidant Capacity
           of Different Parts of Averrhoa carambola L.

    • Authors: Md Mizanur Rhaman, Mohammad Shoeb, Md Nazrul Islam
      Pages: 147 - 151
      Abstract: Averrhoa carambola L. belonging to the Oxalidaceae family has fruits with attractive star shape. Total phenolic and flavonoid content and antioxidant capacity of various parts of A. carambola have been studied to explore active extracts for novel antioxidant compounds. Methanol extract of bark contained the highest amount of phenolic constituent (125 mg GAE/g of dry extract). However, hexane, dichloromethane and methanol extracts contained the maximum number of flavonoids and were 45, 92 and 72 mg QE/g of dry extract, respectively. Since the bark possessed the highest antioxidant capacity, it contained more phenolic compounds than other extracts of fruits and leaves. Total antioxidant capacity of hexane, dichloromethane and methanol extracts of bark were 62, 117 and 151 mg AAE/g of dry extract, respectively. The results recommend that the bark part can be a good source of phenolic compounds as it showed the highest antioxidant capacity. The fruit and leave parts are also rich sources of antioxidant compounds. Dhaka Univ. J. Pharm. Sci. 21(2): 147-151, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63115
      Issue No: Vol. 21, No. 2 (2022)
  • Evaluation of the Formulation of Combined Dosage Form of Albendazole and
           Mebendazole through In vitro Physicochemical and Anthelmintic Study

    • Authors: Kaniz Fatema, BK Sajeeb, KM Yasif Kayes Sikdar, ASM Monjur Al Hossain, Sitesh C Bachar
      Pages: 153 - 163
      Abstract: In the current study, the combination of albendazole and mebendazole was analyzed as a potential anthelmintic agent against Lumbricus terrestris (commonly known as earthworms). The in vitro analysis showed the combination of 400 mg albendazole and 300 mg mebendazole had more significant therapeutic activities (mean paralysis time 58 minutes and mean death time 97.33 minutes) than the others. Then the combinations were formulated as tablet using different ratios of excipients where formulation-D performed excellent flow properties (Carr’s index: 14.04±0.27, Hausner’s ratio: 1.19 ± 0.03, Angle of repose: 40.22 ± 0.73). The dosage form prepared from formulation-D had better hardness of 9.40 ± 0.34 kg-N and loss of weight of 0.003 mg compared to other formulations. In terms of disintegration and dissolution studies, formulation-D exhibited excellent properties. The tablet was disintegrated fully within 8.94 ± 0.37 minutes in phosphate buffer (pH 8.3) and dissolution analysis showed R2 of 0.995 for albendazole and 0.991 for mebendazole which were statistically significant. The postformulation anthelmintic study showed that the prepared tablet dosage form was therapeutically effective because it paralyzed and killed all the earthworms within 56 and 85 minutes, respectively. Finally, the tablet was subjected to the scanning electron microscopy (SEM) analysis which confirmed better surface morphology and drug-drug compatibility within the dosage form. The next stage of the work will focus on in vivo analysis for market preparation. Dhaka Univ. J. Pharm. Sci. 21(2): 153-163, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63116
      Issue No: Vol. 21, No. 2 (2022)
  • Evaluation of Sorghum bicolor (L.) Moench on the Reduction of Creatinine
           Levels and Its Antioxidant Properties In vitro

    • Authors: Ogochukwu Immaculate Obika, Aminat Asabi Oyawaluja, Joseph O Oiseoghaede, Olukemi Abiodun Odukoya, Ngozi Afulenu Obika Ndiri
      Pages: 165 - 172
      Abstract: The study investigated the effect of Sorghum bicolor (L.) Moench extract on the renal activity of both normal and ailing patients. Phytochemical analysis, antioxidant activity, vacuum liquid chromatography and TLC were carried out. The creatinine reduction ability was analyzed using Jaffe’s method for clean-catch spot urine samples of normal, diabetic and hypertensive patients. S. bicolor showed strong antioxidant activity with an IC50 value of 52.17 μg/ml, compared to the standard vitamin C with an IC50 value of 40.59 μg/ml. Statistical analysis (ANOVA) result showed a significant difference between the patients’ urine (rows) (p-value = 2.77×10–08) and a significant difference between the dose treatments (columns) (p-value = 8.38×10–14). Whilst different fractions of S. bicolor at different concentrations showed varying effects on the creatinine concentration, it reduced creatinine level in low doses and has antioxidant properties. Dhaka Univ. J. Pharm. Sci. 21(2): 165-172, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63117
      Issue No: Vol. 21, No. 2 (2022)
  • In vitro Comparative Studies of the Leaf Extracts of Four Different Types
           of Calamus Species

    • Authors: Munsifa Sultana, Sajan Das, Mohammad Shahriar, Rumana Akhter, Isa Naina Mohamed, Mohiuddin Ahmed Bhuiyan
      Pages: 173 - 181
      Abstract: The leaf extracts of Calamus tenius, Calamus viminalis, Calamus guruba and Calamus erectus possessed various phytochemicals including alkaloids, carbohydrates, saponins, phenols, tannins, flavonoids, glycosides, fixed oils and steroids. The point of the present investigation was to compare the antioxidant profile of different leaf extracts of these species. In the present study, methanol, ethanol and chloroform extract of leaf of C. tenius, C. viminalis, C. guruba and C. erectus were explored for in-vitro thrombolytic activity, membrane stabilizing activity by using hypotonic solution-induced & heat-induced hemolysis and antioxidant profile. Ethanol extracts of all plant species demonstrated the highest percentage of clot lysis. During hypotonic solution-induced hemolysis, methanol extract of C. erectus inhibited 59.74% whereas during heat induced condition ethanol extracts of all plant species demonstrated the highest percentage inhibition of hemolysis of RBCs. The screenings of the plants revealed that leaf extracts contain phenolic and flavonoid contents in great amount with the high level of antioxidant capacity. The chloroform extract of C. tenius (2.45 μg/ml) and methanol extract of C. erectus (1.74 μg/ml) leaf showed potent DPPH and H2O2 scavenging activity, respectively. The nitric oxide scavenging activity was not significantly different for methanol, ethanol and chloroform extracts. Methanol, ethanol and chloroform extracts of these four plants showed medium to moderate reducing power and cupric reducing capacity in comparison to standard. A strong relationship was found between the antioxidant activity of the extracts with their total phenolic and flavonoid contents. Dhaka Univ. J. Pharm. Sci. 21(2): 173-181, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63118
      Issue No: Vol. 21, No. 2 (2022)
  • Antiproliferative and Antibacterial Potentials of Endophytic Fungi
           Associated with Bangladeshi Medicinal Plant Tinospora Cordifolia

    • Authors: Gazi Monjur Murshid, Md Hossain Sohrab, Khondoker Shahin Ahmed, Mohammad Mehedi Masud, Md Abdul Mazid
      Pages: 183 - 194
      Abstract: Endophytes provide mutual benefits and produce various biologically active secondary metabolites in plants. Our study was designed to isolate and identify fungal endophytes from fresh leaf and bark of Tinospora cordifolia, coupled with their bioactivity and preliminary chemical screening. Six endophytic fungi were isolated using surface sterilization technique. The fungi were identified by microscopic and molecular characterization and confirmed TCLE-1 as Fusarium perseae, TCLE-2 as Fusarium keratoplasticum, TCLE-3 as fusarium macrosporum, TCBE-1 as Fusarium falciforme and TCBE-2 as well as TCBE-3 leaving unidentified. Isolated strains were cultured in large scale on potato dextrose agar (PDA) medium and were extracted using ethyl acetate. Antibacterial activity of fungal extracts was performed by disc diffusion method and cytotoxicity using HeLa cell line by MTT assay. In antimicrobial test, all the fungal extracts except TCBE-2 showed moderate to potent activity in comparison to the standard kanamycin. All, except TCBE-2, demonstrated significant cytotoxic activity on HeLa cell. Preliminary chemical profiling using thin liquid chromatography (TLC) and analytical high performance liquid chromatography techniques indicated the presence of secondary metabolites in fungal extracts. In conclusion, endophytic fungi reside in the T. cordifolia, a native medicinal plant in Bangladesh, could be a potent source of putative antibacterial and anticancer compounds. Dhaka Univ. J. Pharm. Sci. 21(2): 183-194, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63119
      Issue No: Vol. 21, No. 2 (2022)
  • Study of Risk Factors and Assessment of Hematotoxicity and Oxidative
           Stress Among Women Stroke Patient with Metabolic Syndrome

    • Authors: Derouiche Samir, Salem Saadia, Leguemairi Maroua
      Pages: 195 - 203
      Abstract: This study aims at evaluating some risk factors and the variation of certain hematological and oxidative stress markers in women with stroke disease. The observation (clinical study) was done on 130 voluntary women, divided into metabolic syndrome patients with and without stroke disease. Risk factors were estimated by Chi-square test. Results demonstrated that the high levels of family stress, self-medication and anticoagulants treatment were the most dangerous risk factors to stroke diseases, whereas brushing of teeth daily had an important protective factors against participants from disease. From biological study, results showed that RBC, hemoglobin, GSH and total thiol levels were significantly decreased (p<0.05) while WBC, neutrophile, platelet, MDA, SOD, ORAC and vit C levels were significantly increased (p<0.05) in women with metabolic syndrome (MS) + stroke patients as compared to MS patients without stroke. In conclusion, several socioeconomic and clinical factors contributed to the dispersion and development of the stroke. In addition, oxidative stress during metabolic syndrome contributes to the development of stroke disease. Dhaka Univ. J. Pharm. Sci. 21(2): 195-203, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63120
      Issue No: Vol. 21, No. 2 (2022)
  • Influence of Cardiologists’ Demographic Profile on Overall Satisfaction
           Towards Marketing Mix Strategies

    • Authors: Jesmin Sultana, Mohammad Saifuddin, Zakir Hossain Bhuiyan
      Pages: 205 - 215
      Abstract: This study aims to investigate the influence of cardiologists’ demographic characteristics on their satisfaction towards marketing mix strategies (MMS) employed by pharmaceutical industries in Bangladesh. Cardiologists (156) were asked to rate the importance of variables of MMS indicating their degree of agreement with satisfaction statement using a 5-point Likert scale. The variables of marketing mix (4Ps) that can be ranked as top 5 out of 14 variables according to their Spearman correlation coefficients are - brand image (r = 0.532); selling skill of medical representatives (r = 0.507), place of retail pharmacy (r = 0.484), promotional policies (r = 0.476) and continuous medical education program for doctors (r = 0.345). Though the overall mean satisfaction score of females (M = 4.06, SD = 0.87) is higher than that of male (M=3.84, SD =1.02), the difference is not significant; p = 0.260, Cohen’s d = 0.217 showed the effect is small. Experience above 10 years was labeled as high (41%), otherwise low (59%). Experience had substantial influence on perceived satisfaction towards promotion. Finally, overall satisfaction scores varied based on academic qualification of cardiologists; p < 0.05, and Eta-squared = 0.068 implies medium effect. The highest overall satisfaction score was attained for D. Card and others (M = 4.32, SD = 0.82) and the lowest is for MD (M = 3.57, SD =10.9). Cardiologists’ satisfaction score towards product (the lowest is for MD and the highest is for D. Card and others); p < 0.05; Eta-squared = 0.05 (small effect) and promotion (the lowest is for MBBS and the highest is for D. Card and others) vary significantly according to their academic qualification, p < 0.05; Eta-squared = 0.095 implies medium effect. Dhaka Univ. J. Pharm. Sci. 21(2): 205-215, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63121
      Issue No: Vol. 21, No. 2 (2022)
  • Ethnobotanical Study on Medicinal Plants Used by the Ethnic People of
           Khagrachhari District, Bangladesh

    • Authors: BK Sajeeb, Mohammad Zashim Uddin, Ritesh Bachar, Sitesh C Bachar
      Pages: 217 - 230
      Abstract: The present study deals with important ethnopharmacological information, both in qualitative and quantitative manners on medicinal plants of Khagrachhari district of Bangladesh. The survey was conducted in a period of six months from January 2016 to June 2016 and was interviewed among 155 ethnic people including tribal, Bengalis and 14 traditional health practitioners of eight upazillas in open and semi structured form. The most of the interviewers were Chakma (82%), Marma (8%) and the rest were Tripura (2%) and Bengalis (8%). The total ethnomedicinal plant species was 94, among them 92 were angiosperms, one was gymnosperm and one fern. The plant species belonging to 44 families and 86 generas are used to treat about 53 types of ailments. The different life forms among the species are 28 herbs, 25 trees, 24 shrubs and 17 climbers. The survey showed that the most commonly used plant part was leaves (34.55%) and the most frequent method of preparation was extraction (39.18%) against different ailments. The major treatment options of the medicinal plants of Khagrachhari hilly areas are identified from the study and recommended to take immediate measures for conservation of traditional knowledge of the area. This study showed a hopeful perception for future studies, flaking light on taking immediate measures on inventory of medicinal plants of hilly areas, documentation of verbal information, conservation of threatened plant species, sustainable management of risky areas and preservation of traditional knowledge of herbal medicine in Khagrachhari district, Bangladesh. Dhaka Univ. J. Pharm. Sci. 21(2): 217-230, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63122
      Issue No: Vol. 21, No. 2 (2022)
  • Phytochemical, Biochemical and Pharmacological Properties of Plantago
           ovata (Ispaghula Husk) – A Review

    • Authors: Kakoli Sutradhar, Md Rafat Tahsin, Sania Ashrafi, Sonia Ferdousy, Tahmina Akter, Fahima Aktar, Jakir Ahmed Chowdhury, Abu Asad Chowdhury, Shaila Kabir, Md Shah Amran
      Pages: 231 - 243
      Abstract: The plantation, evolvement, phytochemical, pharmaceutical and pharmacological properties of Plantago ovata have been reviewed to reconnoiter the plant’s diverse properties. P. ovata belonging to the family Plantaginaceae is a perennial plant native to the Mediterranean area, particularly Southern Europe, North Africa and West Asia. It has a variety of medicinal and pharmacological effects as it is frequently employed in a variety of medications for its medicinal features such as mucilage, super-disintegrant, gelling agent and suspending agent as well as pharmacological effects such as anti-diarrheal, anti-constipation, wound curer, hypocholesterolemic and hypoglycemia. That’s why, P. ovata may be utilized to make a variety of medicinal products as well as a safe and effective ethnobotanical cure for different health problems. A number of market preparations of Ispaghula are also available in the local market of Bangladesh. Information regarding diversified properties of P. ovata collected from different electronic databases (PubMed, Springer link, MDPI link, ResearchGate, Google, Google Scholar and Science Direct) have been summarized here to support the researchers to retrieve information about P. ovata. Dhaka Univ. J. Pharm. Sci. 21(2): 231-243, 2022 (December)
      PubDate: 2022-12-28
      DOI: 10.3329/dujps.v21i2.63123
      Issue No: Vol. 21, No. 2 (2022)
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