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- Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Acute Coronary
Syndrome: A Modern Cinderella'-
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Abstract: Publication date: Available online 10 July 2024Source: Clinical TherapeuticsAuthor(s): Paschalis Karakasis, Nikolaos Fragakis, Konstantinos Kouskouras, Theodoros Karamitsos, Dimitrios Patoulias, Manfredi Rizzo
- Evolution of Drug Development and Regulatory Affairs: The Demonstrated
Power of Artificial Intelligence-
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Abstract: Publication date: Available online 8 July 2024Source: Clinical TherapeuticsAuthor(s): Linda Nene, Brian Thabile Flepisi, Sarel Jacobus Brand, Charlise Basson, Marissa Balmith
- Repurposing Drugs to Treat Novel Infections: A Proposal for a
Decision-Making Framework for Clinicians-
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Abstract: Publication date: Available online 4 July 2024Source: Clinical TherapeuticsAuthor(s): Saroj Jayasinghe
- No Differences in Kidney Function Decline Between People With Type 2
Diabetes Starting a Sodium-Glucose Cotransporter 2 Inhibitor or a
Glucagon-like Peptide-1 Receptor Agonist: A Real-world Retrospective
Comparative Observational Study-
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Abstract: Publication date: Available online 4 July 2024Source: Clinical TherapeuticsAuthor(s): Sara Bodini, Silvia Pieralice, Luca D'Onofrio, Carmen Mignogna, Lucia Coraggio, Rocco Amendolara, Renata Risi, Mauro Salducci, Raffaella Buzzetti, Ernesto Maddaloni
- Successful Subcutaneous Immunoglobulin Therapy in a Case Series of
Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Per Sjogren, Bjorn Bragée, Sven Britton
- Role of Anti-Inflammatory Diet and Fecal Microbiota Transplant in
Psoriatic Arthritis-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Rajesh Gopalarathinam, Reethika Sankar, Sizheng Steven Zhao
- Direct Oral Anticoagulants and Concomitant Anti-seizure Medications: A
Retrospective, Case–Control Study in a Real-World Setting-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Eugenia Rota, Paolo Immovilli, Irene Pappalardo, Roberta Risso, Gabriele Zuccotti, Sergio Agosti, Nicola Morelli, Maria Elena Rovere, Ilaria Costa, Maria Luisa D'Orsi
- The International Working Group on New Developments in Pharmacovigilance:
Advancing Methods and Communication in Pharmacovigilance-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Dawn Cooper, Robert W. Platt, Florence van Hunsel, Miranda Davies, Alison Yeomans, Samantha Lane, Saad Shakir
- Knowledge Graphs in Pharmacovigilance: A Scoping Review
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Manfred Hauben, Mazin Rafi, Ibrahim Abdelaziz, Oktie Hassanzadeh
- Knowledge Graphs in Pharmacovigilance: A Step-By-Step Guide
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Manfred Hauben, Mazin Rafi
- A Retrospective Case Series Analysis of Pregnancy and COVID-19 Based on a
Global Postmarketing COVID-19 Surveillance Program-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Elena Beyzarov, Yan Chen, Patrick Caubel
- Tacrolimus Related Acute Pancreatitis: An Observational, Retrospective,
Pharmacovigilance Study-
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Hui Yang, Zhuoling An, Yong Zhao, Hezhe Lu
- Pharmacovigilance: A Cauldron of Old and New
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Abstract: Publication date: July 2024Source: Clinical Therapeutics, Volume 46, Issue 7Author(s): Paul Beninger
- Effectiveness of Mesotherapy in Post-COVID Pain Syndrome: Retrospective
Cohort Study of 96 Patients-
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Abstract: Publication date: Available online 22 June 2024Source: Clinical TherapeuticsAuthor(s): İlknur Topal, Onur Yılmaz
- Combination of High-Dose Daptomycin and Ceftriaxone for Cardiac
Implantable Electronic Device Infections: A 10-Year Experience-
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Abstract: Publication date: Available online 24 August 2024Source: Clinical TherapeuticsAuthor(s): Giacomo Ponta, Martina Ranzenigo, Alessandra Marzi, Chiara Oltolini, Chiara Tassan Din, Caterina Uberti-Foppa, Vincenzo Spagnuolo, Patrizio Mazzone, Paolo Della Bella, Paolo Scarpellini, Antonella Castagna, Marco Ripa
- Effect of Raloxifene Treatment on Apolipoproteins and Lipoprotein(a)
Concentrations in Postmenopausal Women: A Meta-Analysis of Randomized
Controlled Trials-
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Abstract: Publication date: Available online 23 August 2024Source: Clinical TherapeuticsAuthor(s): Xinyi Liao, Jian Deng, Lei Du, Benjamin Hernández-Wolters, Kousalya Prabahar, Hamed Kord-Varkaneh
- Racial Comparison of the Pharmacokinetics and Safety of Fixed-Dose
Combination of Dapagliflozin/Sitagliptin in Western and Korean Healthy
Adults-
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Abstract: Publication date: Available online 23 August 2024Source: Clinical TherapeuticsAuthor(s): Pradeep B. Lukka, Weifeng Tang, Ann Hammarstedt, Tom Conrad, Maria Heijer, Cecilia Karlsson, David W. Boulton
- Cost-effectiveness of Azvudine for High-risk Outpatients With
Mild-to-moderate Coronavirus Disease 2019 in China-
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Abstract: Publication date: Available online 18 August 2024Source: Clinical TherapeuticsAuthor(s): Hui Yang, Zhaojian Wang, Chunping Wang, Ying Zhang, Sheng Han, Zhuoling An
- Aspirin and Ticagrelor Versus Aspirin and Clopidogrel or Prasugrel and the
Effect on Staphylococcal-Associated Infections: A Real-world Study-
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Abstract: Publication date: Available online 16 August 2024Source: Clinical TherapeuticsAuthor(s): Hani Essa, Wern Yew Ding, Faraz Rana, Sizheng Steven Zhao, Matthew Anson, Philip Austin, Gema Hernández, Pankaj Lal, Gregory Y.H. Lip, Uazman Alam
- Weight Loss With Once-nightly Sodium Oxybate for the Treatment of
Narcolepsy: Analysis From the Phase III Randomized study Evaluating the
efficacy and SafeTy of a ONce nightly formulation of sodium oxybate
(REST-ON) Trial-
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Abstract: Publication date: Available online 16 August 2024Source: Clinical TherapeuticsAuthor(s): Thomas Roth, Anne Marie Morse, Richard Bogan, Asim Roy, Jennifer Gudeman, Yves Dauvilliers
- Longitudinal Vasoactive Inotrope Score Trajectories and Their Prognostic
Significance in Critically Ill Sepsis Patients: A Retrospective Cohort
Analysis-
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Abstract: Publication date: Available online 16 August 2024Source: Clinical TherapeuticsAuthor(s): Shiji Xiao, Qiufeng Zhuang, Yinling Li, Zhibin Xue
- Current Approaches in Postapproval Vaccine Safety Studies Using Real-World
Data: A Systematic Review of Published Literature-
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Abstract: Publication date: Available online 13 August 2024Source: Clinical TherapeuticsAuthor(s): Juan (Joanne) Wu, Manfred Hauben, Muhammad Younus
- Pharmacokinetics, Safety, Tolerability, and Exploratory Efficacy of
Upadacitinib in Children with Severe Atopic Dermatitis-
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Abstract: Publication date: Available online 13 August 2024Source: Clinical TherapeuticsAuthor(s): Yuli Qian, Eliza M. Raymundo, Shuai Hao, Kristina Unnebrink, Gweneth F. Levy, Henrique D. Teixeira, Alvina D. Chu, Zachary A. Zinn, Amy S. Paller, Wei Liu, Mohamed-Eslam F. Mohamed
- A Phase I Dose-Escalation Study of The Safety, Tolerability,
Pharmacokinetics, and Pharmacodynamics of Polyethylene
Glycol-Erythropoietin (PEG-EPO) in Healthy Subjects-
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Abstract: Publication date: Available online 8 August 2024Source: Clinical TherapeuticsAuthor(s): Chaoying Hu, Wanling Sun, Yuanyuan Wu, Junlong Huang, Xiangrong Zhang, Lan Zhang
- The Predictive Potential of C-Peptide in Differentiating Type 1 Diabetes
From Type 2 Diabetes in an Outpatient Population in Abu Dhabi-
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Abstract: Publication date: Available online 8 August 2024Source: Clinical TherapeuticsAuthor(s): Sajid Iqbal, Abdulrahim Abu Jayyab, Ayah Mohammad Alrashdi, Syed Shujauddin, Josep Lluis Clua-Espuny, Silvia Reverté-Villarroya
- HARMONIZE Asia: A Phase III Randomized Study to Investigate the Efficacy
and Safety of Sodium Zirconium Cyclosilicate in Patients with Hyperkalemia
in China-
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Abstract: Publication date: Available online 6 August 2024Source: Clinical TherapeuticsAuthor(s): Xinling Liang, Wanhong Lu, Xueqing Yu, Hong Cheng, Qiang He, Qingfeng Peng, Zhaohui Ni, Gang Long, Lihua Wang, Wei Chen, Rong Li, June Zhao, Yong Zhang, Vera Lisovskaja, Zhiji Tang
- Artificial Intelligence, Drug Development and Frameworks: An Opportunity
to Enhance Understanding-
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Abstract: Publication date: Available online 5 August 2024Source: Clinical TherapeuticsAuthor(s): Paul Beninger
- Effects of Propolis Consumption on Glycemic Indices and Liver Enzymes in
Adults: A Grading of Recommendations Assessment, Development, and
valuation-assessed Systematic Review and Dose-Response Meta-analysis-
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Abstract: Publication date: Available online 2 August 2024Source: Clinical TherapeuticsAuthor(s): Shaghayegh Adeli, Mahsa Maroofi, Fatemeh Pourteymour Fard Tabrizi, Beitullah Alipour, Marzieh Heidari, Mahdi Vajdi, Mahdieh Abbasalizad-Farhangi
- Pancreatitis and Pancreatic Cancer Risk Among Patients With Type 2
Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors: An Updated
Meta-Analysis of Randomized Controlled Trials-
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Abstract: Publication date: Available online 31 July 2024Source: Clinical TherapeuticsAuthor(s): Adili Tuersun, Guanxin Hou, Gang Cheng
- Cost-Effectiveness Analysis of COMT-Inhibitors as Adjuvant Treatments to
Levodopa in Patients with Advanced Parkinson's Disease-
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Abstract: Publication date: Available online 31 July 2024Source: Clinical TherapeuticsAuthor(s): Nayoung Kwak, Hye-Young Kang, Myung-Jun Lee, Hankil Lee
- Physiologically Based Pharmacokinetic Model for Predicting Omadacycline
Pharmacokinetics and Pharmacodynamics in Healthy and Hepatic Impairment
Populations-
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Abstract: Publication date: Available online 27 July 2024Source: Clinical TherapeuticsAuthor(s): Ailin Zhang, Yuxuan Sun, Meiling Zuo, Huiyu Wei, Jingtao Chen, Mingfeng Zhao, Wenjie Yang, Liqin Zhu
- One-Year Efficacy and Safety of Dulaglutide in Patients With Type 2
Diabetes and Chronic Kidney Disease: A Retrospective Study of Asian
Patients-
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Abstract: Publication date: Available online 27 July 2024Source: Clinical TherapeuticsAuthor(s): Myung Jin Kim, Hwi Seung Kim, Yun Kyung Cho, Chang Hee Jung, Woo Je Lee
- Pharmacogenomic Polygenic Model of Clopidogrel Predicts Recurrent Ischemic
Events in Chinese Patients With Coronary Artery Disease-
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Abstract: Publication date: Available online 26 July 2024Source: Clinical TherapeuticsAuthor(s): Xinyi Zhang, Yuchun Cai, Pei Zhou, Wenchang Nie, Haoning Sun, Yutong Sun, Yuxuan Zhao, Congxiao Han, Chengfu Cao, Jian Liu, Xiaoyan Nie
- SGLT2 Inhibitors, but Not GLP-1 Receptor Agonists, Reduce Incidence of
Gout in People Living With Type 2 Diabetes Across the Therapeutic Spectrum
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Abstract: Publication date: Available online 26 July 2024Source: Clinical TherapeuticsAuthor(s): Frank G. Preston, Matthew Anson, David R. Riley, Gema H. Ibarburu, Alexander Henney, Gregory Y.H. Lip, Daniel J. Cuthbertson, Uazman Alam, Sizheng S. Zhao
- Proton Pump Inhibitors Versus Histamine-2 Receptor Blockers for Stress
Ulcer Prophylaxis on In-Hospital Mortality Among Intensive Care Unit
Patients Hospitalized for Major Adverse Cardiovascular and Cerebrovascular
Events: Retrospective Cohort Study-
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Abstract: Publication date: Available online 26 July 2024Source: Clinical TherapeuticsAuthor(s): Lanxiang Pu, Ting Jia, Shili Su, Liang Yang, Hong Yao, Yujie Su, Zhaowen Chen
- Efficacy and Safety of Pioglitazone Add-on in Patients with Type 2
Diabetes Mellitus Inadequately Controlled with Metformin and
Dapagliflozin: A Multicenter, Randomized, Double-blind, and
Placebo-Controlled Study-
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Abstract: Publication date: Available online 26 July 2024Source: Clinical TherapeuticsAuthor(s): Yun Kyung Cho, Kyung-Soo Kim, Byung-Wan Lee, Jun Hwa Hong, Jae Myung Yu, Soo Lim, Ye An Kim, Chang Beom Lee, Sang Soo Kim, Soo Heon Kwak, Woo Je Lee
- Effectiveness of a Prostacyclin IP Receptor Agonist in Patients With
Pulmonary Arterial Hypertension in the Real-world Andalusian Setting: The
RAMPHA Study-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Rafael Bravo-Marqués, Víctor Becerra-Muñoz, Francisco Espíldora-Hernández, Alejandro Recio-Mayoral, RAMPHA Registry Investigators
- Risk of Enzyme- and Transporter-mediated Drug Interactions With Drugs
Approved by the US Food and Drug Administration in 2022: A Detailed
Analysis of In Vitro and Clinical Data Available in New Drug Application
Reviews-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Jingjing Yu, Yan Wang, Isabelle Ragueneau-Majlessi
- The Efficacy and Tolerability of Irbesartan/Amlodipine Combination Therapy
in Patients With Essential Hypertension Whose Blood Pressure Were not
Controlled by Irbesartan Monotherapy-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Hae-Young Lee, Kyung Wan Min, Kyung Ah Han, Jeong Su Kim, Jeong Cheon Ahn, Moo Hyun Kim, Jin Bae Lee, Sung-Hee Shin, Chong-Jin Kim, Kye Hun Kim, Deok-Kyu Cho, Junghyun Choi, Moo-Yong Rhee, Sung-Ho Her, Weon Kim, Jin Oh Na, Goo-Yeong Cho, Seok Yeon Kim, Gyung-Min Park, Bong-Ki Lee
- Explainable and Interpretable Machine Learning for Antimicrobial
Stewardship: Opportunities and Challenges-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Daniele Roberto Giacobbe, Cristina Marelli, Sabrina Guastavino, Sara Mora, Nicola Rosso, Alessio Signori, Cristina Campi, Mauro Giacomini, Matteo Bassetti
- Antiretroviral Stewardship: Top 10 Questions Encountered by Stewardship
Teams and Solutions to Optimize Therapy-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Mei H. Chang, Yi Guo, Antoinette Acbo, Hongkai Bao, Terrence McSweeney, Christopher A. Vo, Priya Nori
- Comparison of Cefazolin and Ceftriaxone Enterobacterales Susceptibilities
for Inpatient Treatment of Urinary Tract Infections and Risk of
Hospital-onset Clostridioides difficile Infection-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Eric Wombwell, Allison Rosa
- Clinical Impact of Vancomycin MIC on Outcomes in Patients With
Coagulase-negative Staphylococcal Bacteremia-
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Abstract: Publication date: June 2024Source: Clinical Therapeutics, Volume 46, Issue 6Author(s): Wade Wheat, Brenda Simiyu, Gabriela Andonie, Lillian Bellfi
- Clinical Analysis of Different Anesthesia and Analgesia Methods for
Patients Undergoing Uniportal Video-assisted Lung Surgery-
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Abstract: Publication date: Available online 21 July 2024Source: Clinical TherapeuticsAuthor(s): Xuan Gao, Shuwei Wang, Yi Li, Di Zhou, Xuemei Peng
- Balancing Evidence and Need: Variation in US Commercial Payer Coverage of
Esketamine-
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Abstract: Publication date: Available online 21 July 2024Source: Clinical TherapeuticsAuthor(s): Ekwu B. Ochigbo, Molly T. Beinfeld, James D. Chambers
- Pharmacodynamics Between a Dual Delayed-Release Formulation of Low-Dose
Esomeprazole and Famotidine in Healthy Korean Subjects-
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Abstract: Publication date: Available online 20 July 2024Source: Clinical TherapeuticsAuthor(s): Young-Sim Choi, Jun Gi Hwang, Jae-Won Kim, Hyojin Min, Chang-Hwan Seong, Sung Hee Hong, Na Young Kim, Min Kyu Park
- A Pharmacovigilance Florilegium
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Abstract: Publication date: Available online 19 July 2024Source: Clinical TherapeuticsAuthor(s): Manfred Hauben
- Pharmacokinetics and Safety of a 1:1 Mixture of Doxecitine and
Doxribtimine: Open-label Phase 1 Single Ascending Dose and Food Effect
Studies in Healthy Adults-
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Abstract: Publication date: Available online 18 July 2024Source: Clinical TherapeuticsAuthor(s): Aravind Mittur, Susan A. VanMeter, Elmar Orujov, Paul Glidden
- Niraparib Population Pharmacokinetics and Exposure-Response Relationships
in Patients With Newly Diagnosed Advanced Ovarian Cancer-
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Abstract: Publication date: Available online 16 July 2024Source: Clinical TherapeuticsAuthor(s): Bradley J. Monk, Ignacio Romero, Whitney Graybill, Cristina Churruca, David M. O'Malley, Anja Ør Knudsen, Oi Wah Stephanie Yap, Jean-François Baurain, Peter G. Rose, Hannelore Denys, Sharad Ghamande, Carmela Pisano, Michel Fabbro, Elena Ioana Braicu, Paula M. Calvert, Amnon Amit, Emily Prendergast, Adekemi Taylor, Leila Kheibarshekan, Zhi-Yi Zhang
- Ceftobiprole Medocaril Sodium
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Abstract: Publication date: Available online 14 July 2024Source: Clinical TherapeuticsAuthor(s): Paul Beninger
- Givinostat Oral Suspension
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Abstract: Publication date: Available online 12 July 2024Source: Clinical TherapeuticsAuthor(s): Paul Beninger
- The Importance of Ongoing Surveillance, Education, and Due Diligence for
Antimicrobial Stewardship-
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Abstract: Publication date: Available online 4 July 2024Source: Clinical TherapeuticsAuthor(s): Jill L. Maron
- The Safety of Aztreonam Versus Ceftazidime in Patients Labeled With
Penicillin Allergy: A Cohort Study-
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Abstract: Publication date: Available online 27 June 2024Source: Clinical TherapeuticsAuthor(s): Jun Jie Tan, Peijun Yvonne Zhou, Nathalie Grace Sy Chua, Kai Chee Hung, Hui Ling Winnie Lee, Lai Wei Lee, Jia Le Lim, Yun Chun Shena Lim, Yixin Liew, Li Wen Loo, Narendran Koomanan, Boon San Teoh, Yah Chieh Daphne Yii, Siew Yee Thien, Pei Zhi Benjamin Cherng, Chlebicki Maciej Piotr, Lay Hoon Andrea Kwa, Shimin Jasmine Chung
- Antimicrobial Stewardship: A Creative Outlet for Clinicians
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Abstract: Publication date: Available online 17 June 2024Source: Clinical TherapeuticsAuthor(s): Tonya Scardina
- Resmetirom
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Abstract: Publication date: Available online 15 June 2024Source: Clinical TherapeuticsAuthor(s): Paul Beninger
- Comparison of Switching Between Antiretroviral Agents Versus Introducing
Lipid-Lowering Agents for HAART-Induced Dyslipidemia-
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Abstract: Publication date: Available online 8 June 2024Source: Clinical TherapeuticsAuthor(s): Talent Farai Mafumhe, Gideon Regalado, Samuel Oluwaseun Olojede, Sodiq Kolawole Lawal, Onyemaechi Okpara Azu
- Assessing Patient Risk, Benefit, and Outcomes in Drug Development:
Insights From Afatinib Clinical Trials Across Diverse Cancer Indications-
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Abstract: Publication date: Available online 1 June 2024Source: Clinical TherapeuticsAuthor(s): Rafe Hunter Hall, Carson L. Wright, Griffin K. Hughes, Andriana M. Peña, Chase Ladd, Brooke Gardner, Ryan McIntire, Matt Ferrell, Jane Rubenstein, Jordan Tuia, Alyson Haslam, Vinay Prasad, Matt Vassar
- Overview of the Participation of Nurses in Antimicrobial Stewardship
Activities-
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Abstract: Publication date: Available online 1 June 2024Source: Clinical TherapeuticsAuthor(s): Enrique Castro-Sánchez
- Predicting Chronic Pain and Treatment Outcomes Using Machine Learning
Models Based on High-Dimensional Clinical Data From a Large Retrospective
Cohort-
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Abstract: Publication date: Available online 31 May 2024Source: Clinical TherapeuticsAuthor(s): Han Wu, Zhaoyuan Chen, Jiahui Gu, Yi Jiang, Shenjia Gao, Wankun Chen, Changhong Miao
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