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  Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
Showing 1 - 200 of 253 Journals sorted alphabetically
AAPS Journal     Hybrid Journal   (Followers: 24)
AAPS Open     Open Access   (Followers: 4)
AAPS PharmSciTech     Hybrid Journal   (Followers: 6)
AboutOpen     Open Access  
ACS Pharmacology & Translational Science     Hybrid Journal   (Followers: 3)
Acta Pharmaceutica     Open Access   (Followers: 4)
Acta Pharmaceutica Indonesia     Open Access  
Acta Pharmaceutica Sinica B     Open Access   (Followers: 1)
Acta Pharmacologica Sinica     Hybrid Journal   (Followers: 3)
Acta Physiologica Hungarica     Full-text available via subscription  
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 4)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 93)
Advanced Herbal Medicine     Open Access   (Followers: 8)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Pharmacoepidemiology & Drug Safety     Open Access   (Followers: 2)
Advances in Pharmacological and Pharmaceutical Sciences     Open Access   (Followers: 9)
Advances in Pharmacology     Full-text available via subscription   (Followers: 17)
Advances in Pharmacology and Pharmacy     Open Access   (Followers: 5)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 3)
Adverse Drug Reaction Bulletin     Full-text available via subscription   (Followers: 5)
AJP : The Australian Journal of Pharmacy     Full-text available via subscription   (Followers: 8)
Alternatives to Laboratory Animals     Full-text available via subscription   (Followers: 9)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 20)
American Journal of Drug Discovery and Development     Open Access   (Followers: 3)
American Journal of Health-System Pharmacy     Full-text available via subscription   (Followers: 54)
American Journal of Pharmacological Sciences     Open Access   (Followers: 1)
American Journal of Pharmacology and Toxicology     Open Access   (Followers: 23)
American Journal of Therapeutics     Hybrid Journal   (Followers: 13)
Analytical Methods     Hybrid Journal   (Followers: 8)
Annales Pharmaceutiques Francaises     Full-text available via subscription  
Annals of Pharmacotherapy     Hybrid Journal   (Followers: 56)
Annual Review of Pharmacology and Toxicology     Full-text available via subscription   (Followers: 36)
Anti-Infective Agents     Hybrid Journal   (Followers: 5)
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 5)
Antibiotics     Open Access   (Followers: 11)
Antibody Therapeutics     Open Access  
Antiviral Chemistry and Chemotherapy     Open Access   (Followers: 1)
Antiviral Research     Hybrid Journal   (Followers: 8)
Applied Clinical Trials     Full-text available via subscription   (Followers: 7)
Archiv der Pharmazie     Hybrid Journal   (Followers: 2)
Archives of Drug Information     Hybrid Journal   (Followers: 4)
Archives of Pharmacal Research     Full-text available via subscription   (Followers: 2)
Archives of Pharmacy and Pharmaceutical Sciences     Open Access   (Followers: 1)
Archives of Razi Institute     Open Access  
Archivos Venezolanos de Farmacología y Terapéutica     Open Access  
Ars Pharmaceutica     Open Access  
Asian Journal of Medical and Pharmaceutical Researches     Open Access  
Asian Journal of Pharmaceutical Research and Health Care     Open Access   (Followers: 2)
Asian Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
Asian Journal of Pharmaceutics     Open Access   (Followers: 1)
Asian Journal of Research in Medical and Pharmaceutical Sciences     Open Access  
ASSAY and Drug Development Technologies     Hybrid Journal   (Followers: 3)
Australian Journal of Herbal Medicine     Full-text available via subscription   (Followers: 4)
Australian Pharmacist     Full-text available via subscription   (Followers: 7)
Autonomic & Autacoid Pharmacology     Hybrid Journal  
Avicenna Journal of Phytomedicine     Open Access   (Followers: 1)
Bangladesh Journal of Pharmacology     Open Access  
Bangladesh Journal of Physiology and Pharmacology     Open Access  
Bangladesh Pharmaceutical Journal     Full-text available via subscription  
Basic & Clinical Pharmacology & Toxicology     Hybrid Journal   (Followers: 14)
Behavioural Pharmacology     Hybrid Journal   (Followers: 2)
Bioanalysis     Full-text available via subscription   (Followers: 11)
Biochemical Pharmacology     Hybrid Journal   (Followers: 10)
BioDrugs     Full-text available via subscription   (Followers: 8)
Biological & Pharmaceutical Bulletin     Full-text available via subscription   (Followers: 3)
Biomarkers in Drug Development     Partially Free   (Followers: 2)
Biomaterials     Hybrid Journal   (Followers: 55)
Biomedical and Environmental Sciences     Full-text available via subscription   (Followers: 1)
Biomedicine & Pharmacotherapy     Full-text available via subscription   (Followers: 2)
Biometrical Journal     Hybrid Journal   (Followers: 9)
Biopharm International     Full-text available via subscription   (Followers: 20)
Biopharmaceutics and Drug Disposition     Hybrid Journal   (Followers: 10)
BMC Pharmacology     Open Access   (Followers: 2)
BMC Pharmacology & Toxicology     Open Access   (Followers: 8)
Brazilian Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
British Journal of Clinical Pharmacology     Hybrid Journal   (Followers: 30)
British Journal of Pharmacology     Hybrid Journal   (Followers: 17)
British Journal of Pharmacy (BJPharm)     Open Access   (Followers: 2)
Bulletin of Faculty of Pharmacy, Cairo University     Open Access   (Followers: 2)
CADTH Technology Overviews     Free  
Canadian Journal of Pain     Open Access   (Followers: 3)
Canadian Journal of Physiology and Pharmacology     Hybrid Journal   (Followers: 2)
Canadian Pharmacists Journal / Revue des Pharmaciens du Canada     Hybrid Journal   (Followers: 3)
Cancer Biotherapy & Radiopharmaceuticals     Hybrid Journal  
Cancer Chemotherapy and Pharmacology     Hybrid Journal   (Followers: 4)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Therapeutics     Open Access   (Followers: 3)
Cephalalgia Reports     Open Access  
Chemical and Pharmaceutical Bulletin     Full-text available via subscription   (Followers: 1)
Chemical Research in Toxicology     Hybrid Journal   (Followers: 22)
ChemMedChem     Hybrid Journal   (Followers: 9)
Chemotherapy     Full-text available via subscription   (Followers: 3)
Chinese Herbal Medicines     Full-text available via subscription   (Followers: 1)
Chinese Journal of Pharmaceutical Analysis     Full-text available via subscription  
Ciencia e Investigación     Open Access  
Ciência Equatorial     Open Access  
Clinical and Experimental Pharmacology and Physiology     Hybrid Journal   (Followers: 7)
Clinical and Translational Science     Open Access   (Followers: 4)
Clinical Complementary Medicine and Pharmacology     Open Access  
Clinical Drug Investigation     Full-text available via subscription   (Followers: 8)
Clinical Medicine Insights : Therapeutics     Open Access  
Clinical Neuropharmacology     Hybrid Journal   (Followers: 2)
Clinical Pharmacist     Partially Free   (Followers: 12)
Clinical Pharmacokinetics     Full-text available via subscription   (Followers: 28)
Clinical Pharmacology & Therapeutics     Hybrid Journal   (Followers: 45)
Clinical Pharmacology in Drug Development     Hybrid Journal   (Followers: 4)
Clinical Pharmacology: Advances and Applications     Open Access   (Followers: 6)
Clinical Research and Regulatory Affairs     Hybrid Journal   (Followers: 12)
Clinical Therapeutics     Hybrid Journal   (Followers: 34)
Clinical Toxicology     Hybrid Journal   (Followers: 18)
Clinical Trials     Hybrid Journal   (Followers: 18)
CNS Drug Reviews     Open Access   (Followers: 4)
CNS Drugs     Full-text available via subscription   (Followers: 10)
Combination Products in Therapy     Open Access  
Consultant Pharmacist     Full-text available via subscription   (Followers: 2)
Consumer Drugs     Full-text available via subscription  
Contract Pharma     Full-text available via subscription  
Cosmetics     Open Access   (Followers: 4)
CPT : Pharmacometrics & Systems Pharmacology     Open Access   (Followers: 11)
Critical Reviews in Clinical Laboratory Sciences     Hybrid Journal   (Followers: 16)
Critical Reviews in Therapeutic Drug Carrier Systems     Full-text available via subscription   (Followers: 5)
Critical Reviews in Toxicology     Hybrid Journal   (Followers: 25)
Current Bioactive Compounds     Hybrid Journal  
Current Cancer Therapy Reviews     Hybrid Journal   (Followers: 5)
Current Clinical Pharmacology     Hybrid Journal   (Followers: 4)
Current Drug Delivery     Hybrid Journal   (Followers: 6)
Current Drug Discovery Technologies     Hybrid Journal   (Followers: 6)
Current Drug Metabolism     Hybrid Journal   (Followers: 5)
Current Drug Safety     Hybrid Journal   (Followers: 8)
Current Drug Targets     Hybrid Journal   (Followers: 5)
Current Drug Therapy     Hybrid Journal   (Followers: 3)
Current Enzyme Inhibition     Hybrid Journal   (Followers: 1)
Current Issues in Pharmacy and Medical Sciences     Open Access   (Followers: 2)
Current Medical Science     Hybrid Journal  
Current Medicinal Chemistry     Hybrid Journal   (Followers: 13)
Current Molecular Pharmacology     Hybrid Journal  
Current Nanoscience     Hybrid Journal  
Current Neuropharmacology     Hybrid Journal   (Followers: 1)
Current Opinion in Pharmacology     Hybrid Journal   (Followers: 9)
Current Pharmaceutical Analysis     Hybrid Journal   (Followers: 1)
Current Pharmaceutical Biotechnology     Hybrid Journal   (Followers: 10)
Current Pharmaceutical Design     Hybrid Journal   (Followers: 11)
Current Pharmacogenomics and Personalized Medicine     Hybrid Journal   (Followers: 3)
Current Pharmacology Reports     Hybrid Journal  
Current Protocols in Pharmacology     Hybrid Journal  
Current Radiopharmaceuticals     Hybrid Journal   (Followers: 1)
Current Research in Drug Discovery     Open Access   (Followers: 2)
Current Research in Pharmacology and Drug Discovery     Open Access   (Followers: 1)
Current Therapeutic Research     Open Access   (Followers: 6)
Current trends in Biotechnology and Pharmacy     Open Access   (Followers: 8)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 4)
Dhaka University Journal of Pharmaceutical Sciences     Open Access  
Die Pharmazie - An International Journal of Pharmaceutical Sciences     Full-text available via subscription   (Followers: 5)
Dose-Response     Open Access  
Drug and Chemical Toxicology     Hybrid Journal   (Followers: 13)
Drug and Therapeutics Bulletin     Hybrid Journal   (Followers: 8)
Drug Delivery     Open Access   (Followers: 8)
Drug Delivery and Translational Research     Hybrid Journal   (Followers: 2)
Drug Design, Development and Therapy     Open Access   (Followers: 3)
Drug Development and Industrial Pharmacy     Hybrid Journal   (Followers: 29)
Drug Development Research     Hybrid Journal   (Followers: 11)
Drug Discovery Today: Technologies     Full-text available via subscription   (Followers: 12)
Drug Metabolism and Disposition     Hybrid Journal   (Followers: 13)
Drug Metabolism and Pharmacokinetics     Hybrid Journal   (Followers: 6)
Drug Metabolism Letters     Hybrid Journal   (Followers: 3)
Drug Metabolism Reviews     Hybrid Journal   (Followers: 8)
Drug Research     Hybrid Journal   (Followers: 3)
Drug Resistance Updates     Hybrid Journal   (Followers: 3)
Drug Safety     Full-text available via subscription   (Followers: 79)
Drug Safety - Case Reports     Open Access   (Followers: 2)
Drug Target Insights     Open Access  
Drug, Healthcare and Patient Safety     Open Access   (Followers: 10)
Drugs     Full-text available via subscription   (Followers: 123)
Drugs & Aging     Full-text available via subscription   (Followers: 9)
Drugs & Therapy Perspectives     Full-text available via subscription   (Followers: 9)
Drugs : Real World Outcomes     Hybrid Journal   (Followers: 1)
Drugs and Therapy Studies     Open Access  
Drugs in R & D     Full-text available via subscription   (Followers: 2)
Drugs of the Future     Full-text available via subscription   (Followers: 8)
East and Central African Journal of Pharmaceutical Sciences     Open Access   (Followers: 1)
Egyptian Pharmaceutical Journal     Open Access  
EJNMMI Radiopharmacy and Chemistry     Open Access  
EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei     Full-text available via subscription  
Emerging Trends in Drugs, Addictions, and Health     Open Access  
Environmental Toxicology and Pharmacology     Hybrid Journal   (Followers: 9)
Epilepsy Research     Hybrid Journal   (Followers: 7)
Ethiopian Pharmaceutical Journal     Full-text available via subscription   (Followers: 1)
EUREKA : Health Sciences     Open Access  
European Journal of Clinical Pharmacology     Hybrid Journal   (Followers: 14)
European Journal of Drug Metabolism and Pharmacokinetics     Hybrid Journal   (Followers: 8)
European Journal of Hospital Pharmacy : Science and Practice (EJHP)     Hybrid Journal   (Followers: 5)
European Journal of Medicinal Plants     Open Access   (Followers: 2)
European Journal of Pharmaceutical Sciences     Hybrid Journal   (Followers: 84)
European Journal of Pharmaceutics and Biopharmaceutics     Hybrid Journal   (Followers: 34)
European Journal of Pharmacology     Hybrid Journal   (Followers: 8)
European Neuropsychopharmacology     Hybrid Journal   (Followers: 9)
European Review for Medical and Pharmacological Sciences     Full-text available via subscription   (Followers: 1)
Experimental and Clinical Psychopharmacology     Full-text available via subscription   (Followers: 7)
Expert Opinion on Drug Delivery     Hybrid Journal   (Followers: 17)
Expert Opinion on Drug Discovery     Hybrid Journal   (Followers: 18)

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Similar Journals
Journal Cover
Clinical Pharmacology & Therapeutics
Journal Prestige (SJR): 1.699
Citation Impact (citeScore): 4
Number of Followers: 45  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0009-9236 - ISSN (Online) 1532-6535
Published by John Wiley and Sons Homepage  [1763 journals]
  • Highlights

    • Free pre-print version: Loading...

      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 16-17, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2619
      Issue No: Vol. 112, No. 1 (2022)
       
  • In This Issue

    • Free pre-print version: Loading...

      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 9-10, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2629
      Issue No: Vol. 112, No. 1 (2022)
       
  • ASCPT News

    • Free pre-print version: Loading...

      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 18-23, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2632
      Issue No: Vol. 112, No. 1 (2022)
       
  • Tackling Challenging Data Integrity Topics in 2020: Update on Good
           Clinical Practice Perspectives from the US FDA and MHRA UK

    • Free pre-print version: Loading...

      Authors: Ni A. Khin; Cheryl Grandinetti, Hayley Dixey, Bei Yu, Rachel Skeete, Kassa Ayalew, Mandy Budwal‐Jagait, Seongeun‐Julia Cho, Arindam Dasgupta, Andrew Fisher, Cynthia Kleppinger, Phillip D. Kronstein, Jennifer Martin, Michael McGuinness, Jean Mulinde, Stephen Vinter, Jason Wakelin‐Smith, Paula Walker, Gail Francis
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 31-43, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2386
      Issue No: Vol. 112, No. 1 (2022)
       
  • Biomarker Qualification at the European Medicines Agency: A Review of
           Biomarker Qualification Procedures From 2008 to 2020

    • Free pre-print version: Loading...

      Authors: Elisabeth Bakker; Natalie M. Hendrikse, Falk Ehmann, Daniëlla S. Meer, Jordi Llinares Garcia, Thorsten Vetter, Viktoriia Starokozhko, Peter G.M. Mol
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 69-80, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2554
      Issue No: Vol. 112, No. 1 (2022)
       
  • Overcoming Barriers to Biosimilar Adoption: Commentary on “Cost to
           Medicare of Delayed Adalimumab Biosimilar Availability”

    • Free pre-print version: Loading...

      Authors: Nitzan Arad; Adam Kroetsch, Mark McClellan
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 25-27, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2403
      Issue No: Vol. 112, No. 1 (2022)
       
  • Quantitative Clinical Pharmacology of CAR T‐Cell Therapy

    • Free pre-print version: Loading...

      Authors: Sarah A. Holstein; Karthik Venkatakrishnan, Piet H. Graaf
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 11-15, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2631
      Issue No: Vol. 112, No. 1 (2022)
       
  • Issue Information

    • Free pre-print version: Loading...

      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 1-5, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2298
      Issue No: Vol. 112, No. 1 (2022)
       
  • Expanding Approved Patient Populations for Rare Disease Treatment Using In
           Vitro Data

    • Free pre-print version: Loading...

      Authors: James L. Weaver; Wendy Wu, Paula L. Hyland, Robert Lim, Patroula Smpokou, Michael Pacanowski
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 58-61, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2414
      Issue No: Vol. 112, No. 1 (2022)
       
  • Pharmacogenomic Clinical Decision Support: A Review, How‐to Guide,
           and Future Vision

    • Free pre-print version: Loading...

      Authors: Dyson T. Wake; D. Max Smith, Sadaf Kazi, Henry M. Dunnenberger
      Abstract: Clinical Pharmacology & Therapeutics, Volume 112, Issue 1, Page 44-57, July 2022.
      PubDate: 2022-06-18T11:39:25-07:00
      DOI: 10.1002/cpt.2387
      Issue No: Vol. 112, No. 1 (2022)
       
  • Development of a Translational Model to Assess the Impact of Opioid
           

    • Free pre-print version: Loading...

      Authors: John Mann; Mohammadreza Samieegohar, Anik Chaturbedi, Joel Zirkle, Xiaomei Han, S. Farzad Ahmadi, Amy Eshleman, Aaron Janowsky, Katherine Wolfrum, Tracy Swanson, Shelley Bloom, Albert Dahan, Erik Olofsen, Jeffry Florian, David G. Strauss, Zhihua Li
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-29T04:57:51-07:00
      DOI: 10.1002/cpt.2696
       
  • Liquid biopsies or therapeutic drug monitoring for CYP activity profile
           determination

    • Free pre-print version: Loading...

      Authors: Chris S. Pridgeon; Inger Johansson, Magnus Ingelman‐Sundberg
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-29T02:29:28-07:00
      DOI: 10.1002/cpt.2695
       
  • Effects of mexiletine and lacosamide on nerve excitability in healthy
           subjects: a randomized, double‐blind, placebo‐controlled, crossover
           study

    • Free pre-print version: Loading...

      Authors: Titia Q. Ruijs; Ingrid W. Koopmans, Marieke L. de Kam, Michiel J. van Esdonk, Martin Koltzenburg, Geert Jan Groeneveld, Jules A.A.C. Heuberger
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-28T12:00:00-07:00
      DOI: 10.1002/cpt.2694
       
  • Considerations for Human ADME strategy and design paradigm shift(s)
           ‐ an Industry white paper

    • Free pre-print version: Loading...

      Authors: Graeme C. Young; Douglas K. Spracklin, Alexander D. James, Mette G. Hvenegaard, Graeme Scarfe, David S. Wagner, Katrin Georgi, Hanno Schieferstein, Inga Bjornsdottir, Bianca van Groen, Andrea A. Romeo, Kenneth C. Cassidy, Georges Da‐violante, Bojan Bister, Stefan Blech, Ramaswamy lyer, Simone I. Schulz, Filip Cuyckens, Patricia Moliner
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-22T09:07:45-07:00
      DOI: 10.1002/cpt.2691
       
  • Development of a Translational Exposure‐Bracketing Approach to
           Streamline the Development of Hormonal Contraceptive Drug Products

    • Free pre-print version: Loading...

      Authors: Brian Cicali; Lais Da Silva, Amir Sarayani, Karthik Lingineni, Michelle Pressly, Soyoung Kim, Thomas Wendl, Joachim Hoechel, Valvanera Vozmediano, Almut G Winterstein, Joshua D Brown, Stephan Schmidt, Rodrigo Cristofoletti
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-20T08:32:57-07:00
      DOI: 10.1002/cpt.2690
       
  • Clinical Relevance of Organic Anion Transporting Polypeptide 1B–Mediated
           Hepatic Uptake for High‐Permeability Drugs: A Perspective

    • Free pre-print version: Loading...

      Authors: Manthena V.S. Varma
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-20T05:12:11-07:00
      DOI: 10.1002/cpt.2678
       
  • Current Perspective on Residual Knowledge Gaps in the Assessment of
           Transporter‐Mediated Drug Interactions

    • Free pre-print version: Loading...

      Authors: Xinning Yang; Kellie Reynolds, Rajanikanth Madabushi, Shiew‐Mei Huang
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-20T01:06:27-07:00
      DOI: 10.1002/cpt.2671
       
  • Ziritaxestat Drug–Drug Interaction with Oral Contraceptives: Role of
           SULT1E1 Inhibition

    • Free pre-print version: Loading...

      Authors: Eric Helmer; Negin Karimian, Karen Van Assche, Ineke Seghers, Sandrine Le Tallec, Ganesh Cherala, Graham Scott, Florence S. Namour
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-17T12:00:00-07:00
      DOI: 10.1002/cpt.2689
       
  • Physiologically Based Pharmacokinetic Modelling‐Guided Dose Management
           of Oral Anticoagulants when Initiating Paxlovid for COVID‐19 Treatment

    • Free pre-print version: Loading...

      Authors: Ziteng Wang; Eric Chun Yong Chan
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-16T11:46:14-07:00
      DOI: 10.1002/cpt.2687
       
  • Pharmacokinetics of Oral Nirmatrelvir/Ritonavir, a Protease Inhibitor for
           Treatment of COVID‐19, in Subjects With Renal Impairment

    • Free pre-print version: Loading...

      Authors: Sima S. Toussi; Joel Michael Neutel, Jesus Navarro, Richard Alfred Preston, Haihong Shi, Olga Kavetska, Robert R LaBadie, Michael Binks, Phylinda LS Chan, Neil Demers, Brian Corrigan, Bharat Damle
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-16T11:46:13-07:00
      DOI: 10.1002/cpt.2688
       
  • Landscape Analysis of the Application of Artificial Intelligence and
           Machine Learning in Regulatory Submissions for Drug Development From 2016
           to 2021

    • Free pre-print version: Loading...

      Authors: Qi Liu; Ruihao Huang, Julie Hsieh, Hao Zhu, Mo Tiwari, Guansheng Liu, Daphney Jean, M. Khair ElZarrad, Tala Fakhouri, Steven Berman, Billy Dunn, Matthew C. Diamond, Shiew‐Mei Huang
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-16T01:03:34-07:00
      DOI: 10.1002/cpt.2668
       
  • Response to: Real‐World Data on the Risk of Ventricular Arrhythmias
           with Sulfonamides

    • Free pre-print version: Loading...

      Authors: Nehal Islam; Henok Tadesse Ayele, Oriana H. Y. Yu, Antonios Douros, Kristian B. Filion
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-14T11:42:50-07:00
      DOI: 10.1002/cpt.2669
       
  • Calibration and Validation of a Mechanistic COVID‐19 Model for
           Translational Quantitative Systems Pharmacology – A Proof‐of‐Concept
           Model Development for Remdesivir

    • Free pre-print version: Loading...

      Authors: Mohammadreza Samieegohar; James L Weaver, Kristina E. Howard, Anik Chaturbedi, John Mann, Xiaomei Han, Joel Zirkle, Ghazal Arabidarrehdor, Rodney Rouse, Jeffry Florian, David G. Strauss, Zhihua Li
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-13T12:47:56-07:00
      DOI: 10.1002/cpt.2686
       
  • Effect of Chronic Kidney Disease on the Renal Secretion via Organic Anion
           Transporters 1/3: Implications for Physiologically‐Based Pharmacokinetic
           Modeling and Dose Adjustment

    • Free pre-print version: Loading...

      Authors: Shawn Pei Feng Tan; Daniel Scotcher, Amin Rostami‐Hodjegan, Aleksandra Galetin
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-13T02:39:34-07:00
      DOI: 10.1002/cpt.2642
       
  • Dihydropyrimidine Dehydrogenase Deficiency and Implementation of Upfront
           DPYD Genotyping

    • Free pre-print version: Loading...

      Authors: Cassandra White; Rodney J. Scott, Christine Paul, Andrew Ziolkowski, David Mossman, Stephen B. Fox, Michael Michael, Stephen Ackland
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-12T11:14:05-07:00
      DOI: 10.1002/cpt.2667
       
  • Protecting the Kidney: The Unexpected Logic of Inhibiting a Glucose
           Transporter

    • Free pre-print version: Loading...

      Authors: Volker Vallon; Young Chul Kim
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-11T11:34:22-07:00
      DOI: 10.1002/cpt.2651
       
  • Transporters and Toxicity: Insights from the International Transporter
           Consortium Workshop 4

    • Free pre-print version: Loading...

      Authors: Michael J. Hafey; Lauren M. Aleksunes, Christy C. Bridges, Kenneth R. Brouwer, Huan‐Chieh Chien, Elaine M. Leslie, Shuiying Hu, Yang Li, Jinshan Shen, Alex Sparreboom, Jason Sprowl, Donald Tweedie, Yurong Lai
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-10T12:14:42-07:00
      DOI: 10.1002/cpt.2638
       
  • Assessing the QTcF prolongation of bedaquiline and delamanid
           coadministration to predict the cardiac safety of simplified dosing
           regimens

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      Authors: Lénaïg Tanneau; Mats O. Karlsson, Susan L. Rosenkranz, Yoninah S. Cramer, Justin Shenje, Caryn M. Upton, Joel Morganroth, Andreas H. Diacon, Gary Maartens, Kelly E. Dooley, Elin M. Svensson
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-10T12:00:00-07:00
      DOI: 10.1002/cpt.2685
       
  • Oral Glucose Tolerance Test: An Informative Endpoint or an Added Burden in
           Metformin Drug–Drug Interaction Studies'

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      Authors: Anees M. Dauki; Chia‐Hsiang Hsueh, Ganesh Cherala, Ahmed A. Othman
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-10T11:39:32-07:00
      DOI: 10.1002/cpt.2650
       
  • A Pharmacokinetics–Time to Alleviation of Symptoms Model to Support
           Extrapolation of Baloxavir Marboxil Clinical Efficacy in Different Ethnic
           Groups with Influenza A or B

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      Authors: Sylvie Retout; Stefan De Buck, Sébastien Jolivet, Vincent Duval, Valérie Cosson
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-10T09:21:16-07:00
      DOI: 10.1002/cpt.2648
       
  • Population Pharmacokinetic Models for Direct Oral Anticoagulants: A
           Systematic Review and Clinical Appraisal Using Exposure Simulation

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      Authors: Jean Terrier; Frédéric Gaspar, Monia Guidi, Pierre Fontana, Youssef Daali, Chantal Csajka, Jean‐Luc Reny
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-09T10:58:42-07:00
      DOI: 10.1002/cpt.2649
       
  • Comparative effectiveness and safety of different combinations of
           antithrombotic regimens in atrial fibrillation patients with stent
           insertions

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      Authors: Han‐Hsin Chueh; Shih‐Tsung Huang, Shang‐Hung Chang, Shin‐Yi Lin, Fei‐Yuan Hsiao
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-09T07:10:13-07:00
      DOI: 10.1002/cpt.2684
       
  • Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative
           Fluorine NMR Spectroscopy: A Novel Approach For Accelerating Drug
           Development

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      Authors: Ravi Shankar P. Singh; Gregory S. Walker, Eugene P. Kadar, Loretta M. Cox, Heather Eng, Raman Sharma, Arthur J. Bergman, Lien Van Eyck, Frances Hackman, Sima S. Toussi, Amit S. Kalgutkar, R. Scott Obach
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-09T07:05:32-07:00
      DOI: 10.1002/cpt.2683
       
  • Population Pharmacokinetics and Pharmacodynamics of the Therapeutic and
           Adverse Effects of Ketamine in Patients with Treatment‐Refractory
           Depression

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      Authors: Ahmad Y. Abuhelwa; Andrew A. Somogyi, Colleen K. Loo, Paul Glue, Daniel T. Barratt, David J.R. Foster
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-09T03:35:40-07:00
      DOI: 10.1002/cpt.2640
       
  • Extrapolation of Efficacy from Adults to Pediatric Patients of Drugs for
           Treatment of Partial Onset Seizures (POS): A Regulatory Perspective

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      Authors: Shailly Mehrotra; Atul Bhattaram, Kevin Krudys, Michael Bewernitz, Ramana Uppoor, Mehul Mehta, Tao Liu, Philip Sheridan, Norman Hershkowitz, Nicholas Kozauer, Eric Bastings, Billy Dunn, Angela Yuxin Men
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-08T11:55:09-07:00
      DOI: 10.1002/cpt.2681
       
  • Exposure of fexofenadine, but not pseudoephedrine, is markedly decreased
           by green tea extract in healthy volunteers

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      Authors: Shingen Misaka; Yuko Ono, R. Verena Taudte, Eva Hoier, Hiroshi Ogata, Tomoyuki Ono, Jörg König, Hiroshi Watanabe, Martin F. Fromm, Kenju Shimomura
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-08T11:55:02-07:00
      DOI: 10.1002/cpt.2682
       
  • Characteristics of the Compassionate Use Program in Japan: An Analysis of
           Expanded Access Clinical Trials from 2016 to 2021

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      Authors: Hideki Maeda; Marika Uchida, Mikiko Kusano, Katsura Tsukamoto, Moeka Yamanoi
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-07T06:49:40-07:00
      DOI: 10.1002/cpt.2641
       
  • Recommendations for the Management of Drug–Drug Interactions Between the
           COVID‐19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications

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      Authors: Catia Marzolini; Daniel R. Kuritzkes, Fiona Marra, Alison Boyle, Sara Gibbons, Charles Flexner, Anton Pozniak, Marta Boffito, Laura Waters, David Burger, David J. Back, Saye Khoo
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-07T06:29:17-07:00
      DOI: 10.1002/cpt.2646
       
  • Renal Transporter‐Mediated Drug‐Biomarker Interactions of the
           Endogenous Substrates Creatinine and N1‐Methylnicotinamide: A PBPK
           Modeling Approach

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      Authors: Denise Türk; Fabian Müller, Martin F. Fromm, Dominik Selzer, Robert Dallmann, Thorsten Lehr
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-07T06:19:15-07:00
      DOI: 10.1002/cpt.2636
       
  • Tiny Gatekeepers: Microbial Control of Host Drug Transporters

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      Authors: Than S. Kyaw; Peter J. Turnbaugh
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-06T11:10:17-07:00
      DOI: 10.1002/cpt.2647
       
  • Post‐marketing requirements for cancer drugs approved by the European
           Medicines Agency, 2004‐2014

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      Authors: Avi Cherla; Elias Mossialos, Maximilian Salcher‐Konrad, Aaron S Kesselheim, Huseyin Naci
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-05T12:00:00-07:00
      DOI: 10.1002/cpt.2679
       
  • Reduced All‐Cause Mortality with Bisphosphonates Among Post‐Fracture
           Osteoporosis Patients: A Nationwide Study and Systematic Review

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      Authors: Yu‐Hsuan Hsu; Chia‐Chun Li, Fu‐Wen Liang, Zi‐Yang Peng, Yin‐Fan Chang, Jason C. Hsu, Huang‐Tz Ou, Chih‐Hsing Wu
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-04T10:04:19-07:00
      DOI: 10.1002/cpt.2645
       
  • Coproporphyrin I as an endogenous biomarker to detect reduced OATP1B
           activity and shift in elimination route in chronic kidney disease

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      Authors: Hiroyuki Takita; Daniel Scotcher, Xiaoyan Chu, Ka Lai Yee, Kayode Ogungbenro, Aleksandra Galetin
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-02T12:25:00-07:00
      DOI: 10.1002/cpt.2672
       
  • Combined conventional synthetic disease modifying therapy vs infliximab
           for rheumatoid arthritis: emulating a randomized trial in observational
           data

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      Authors: Andrei Barbulescu; Johan Askling, Saedis Saevarsdottir, Seoyoung C Kim, Thomas Frisell
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-02T12:00:00-07:00
      DOI: 10.1002/cpt.2673
       
  • Genome‐wide association study of simvastatin pharmacokinetics

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      Authors: Anssi J. H. Mykkänen; Suvi Taskinen, Mikko Neuvonen, Maria Paile‐Hyvärinen, E. Katriina Tarkiainen, Tuomas Lilius, Tuija Tapaninen, Janne T. Backman, Aleksi Tornio, Mikko Niemi
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-06-02T12:00:00-07:00
      DOI: 10.1002/cpt.2674
       
  • Considerations for Physiologically Based Modeling in Liver Disease: From
           Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

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      Authors: William A. Murphy; Jeffry Adiwidjaja, Noora Sjöstedt, Kyunghee Yang, James J. Beaudoin, Jessica Spires, Scott Q. Siler, Sibylle Neuhoff, Kim L.R. Brouwer
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-06-02T09:44:58-07:00
      DOI: 10.1002/cpt.2614
       
  • Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug
           Metabolizing Enzyme Thiopurine S‐Methyltransferase

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      Authors: Julika Pristup; Elke Schaeffeler, Sita Arjune, Ute Hofmann, Jose Angel Santamaria‐Araujo, Patrick Leuthold, Nele Friedrich, Matthias Nauck, Simon Mayr, Mathias Haag, Thomas Muerdter, Franz‐Josef Marner, Mary V. Relling, William E. Evans, Guenter Schwarz, Matthias Schwab
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-31T05:07:13-07:00
      DOI: 10.1002/cpt.2637
       
  • Mobocertinib Dose Rationale in Patients with Metastatic NSCLC with EGFR
           Exon 20 Insertions: Exposure–Response Analyses of a Pivotal Phase I/II
           Study

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      Authors: Neeraj Gupta; Anna Largajolli, Han Witjes, Paul M. Diderichsen, Steven Zhang, Michael J. Hanley, Jianchang Lin, Minal Mehta
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-29T12:23:06-07:00
      DOI: 10.1002/cpt.2622
       
  • Clinical relevance of hepatic and renal P‐gp/BCRP inhibition of drugs:
           An International Transporter Consortium perspective

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      Authors: Kunal S. Taskar; Xinning Yang, Sibylle Neuhoff, Mitesh Patel, Kenta Yoshida, Mary F. Paine, Kim L.R. Brouwer, Xiaoyan Chu, Yuichi Sugiyama, Jack Cook, Joseph W. Polli, Imad Hanna, Yurong Lai, Maciej Zamek‐Gliszczynski, The ITC
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-25T08:10:04-07:00
      DOI: 10.1002/cpt.2670
       
  • Regulation of Drug Transport Proteins—From Mechanisms to Clinical
           Impact: A White Paper on Behalf of the International Transporter
           Consortium

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      Authors: Kim L.R. Brouwer; Raymond Evers, Elizabeth Hayden, Shuiying Hu, Cindy Yanfei Li, Henriette E. Meyer zu Schwabedissen, Sibylle Neuhoff, Stefan Oswald, Micheline Piquette‐Miller, Chitra Saran, Noora Sjöstedt, Jason A. Sprowl, Simone H. Stahl, Wei Yue
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-24T03:43:37-07:00
      DOI: 10.1002/cpt.2605
       
  • Pharmacometric and electrocardiographic evaluation of chloroquine and
           azithromycin in healthy volunteers

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      Authors: Palang Chotsiri; Joel Tarning, Richard M Hoglund, James Watson, Nicholas J White
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-22T12:00:00-07:00
      DOI: 10.1002/cpt.2665
       
  • Analysis of Patent and Regulatory Exclusivity for Novel Agents in China
           and the United States: A Cohort Study of Drugs Approved Between 2018 and
           2021

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      Authors: Xingxian Luo; Lina Yang, Xin Du, Jingshu Yang, Feng Qian, Yue Yang
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-22T08:24:57-07:00
      DOI: 10.1002/cpt.2625
       
  • Blockade of Organic Anion Transport in Humans After Treatment With the
           Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine

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      Authors: Jeffry C. Granados; Vibha Bhatnagar, Sanjay K. Nigam
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-22T07:19:45-07:00
      DOI: 10.1002/cpt.2630
       
  • Challenges and Opportunities for Improved Drug‐Drug Interaction
           Predictions for Renal OCT2 and MATE1/2‐K Transporters

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      Authors: Srinivasan Krishnan; Diane Ramsden, Douglas Ferguson, Simone H. Stahl, Joanne Wang, Dermot F. McGinnity, Niresh Hariparsad
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-22T02:18:29-07:00
      DOI: 10.1002/cpt.2666
       
  • Quantitative Proteomics of Hepatic Drug‐Metabolizing Enzymes and
           Transporters in Patients with Colorectal Cancer Metastasis

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      Authors: Areti‐Maria Vasilogianni; Zubida M. Al‐Majdoub, Brahim Achour, Sheila Annie Peters, Jill Barber, Amin Rostami‐Hodjegan
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-21T11:27:32-07:00
      DOI: 10.1002/cpt.2633
       
  • Polygenic Risk Scores for Blood Pressure to Assess the Risk of Severe
           Bevacizumab‐Induced Hypertension in Cancer Patients (Alliance)

    • Free pre-print version: Loading...

      Authors: Julia C.F. Quintanilha; Amy S. Etheridge, Brady J. Graynor, Nicholas B. Larson, Daniel J. Crona, Braxton D. Mitchell, Federico Innocenti
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-21T11:27:15-07:00
      DOI: 10.1002/cpt.2635
       
  • A Biological Basis for Pharmacokinetics: The Remote Sensing and Signaling
           Theory

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      Authors: Sanjay K. Nigam; Jeffry C. Granados
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-21T11:23:00-07:00
      DOI: 10.1002/cpt.2634
       
  • Applying Modeling and Simulations for Rational Dose Selection of Novel
           Toll‐Like Receptor 7/8 Inhibitor Enpatoran for Indications of High
           Medical Need

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      Authors: Lena Klopp‐Schulze; Jamie V. Shaw, Jennifer Q. Dong, Akash Khandelwal, Cristina Vazquez‐Mateo, Kosalaram Goteti
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-21T08:25:04-07:00
      DOI: 10.1002/cpt.2606
       
  • Rifampin drug‐drug‐interaction studies; reflections on the
           nitrosamine impurities issue

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      Authors: Aernout van Haarst; Stephen Smith, Clare Garvin, Natacha Benrimoh, Sabina Paglialunga
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-20T12:00:00-07:00
      DOI: 10.1002/cpt.2652
       
  • New and Emerging Research on Solute Carrier and ATP Binding Cassette
           Transporters in Drug Discovery and Development: Outlook from the
           International Transporter Consortium

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      Authors: Kathleen M. Giacomini; Sook W. Yee, Megan L. Koleske, Ling Zou, Pär Matsson, Eugene C. Chen, Deanna L. Kroetz, Miles A. Miller, Elnaz Gozalpour, Xiaoyan Chu
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-20T10:39:40-07:00
      DOI: 10.1002/cpt.2627
       
  • Model‐Based Prediction of Irinotecan‐Induced Grade 4 Neutropenia in
           Advanced Cancer Patients: Influence of Demographic and Clinical Factors

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      Authors: Spinel Karas; Ron H. J. Mathijssen, Ron H. N. Schaik, Alan Forrest, Tim Wiltshire, Federico Innocenti, Robert R. Bies
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-18T11:44:55-07:00
      DOI: 10.1002/cpt.2621
       
  • Presence of Five Chemotherapeutic Drugs in Breast Milk as a Guide for the
           

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      Authors: David Damoiseaux; Silvia Calpe, Hilde Rosing, Jos H. Beijnen, Alwin D. R. Huitema, Christianne Lok, Thomas P. C. Dorlo, Frédéric Amant
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-18T08:08:48-07:00
      DOI: 10.1002/cpt.2626
       
  • Use of Real‐World Data and Physiologically‐Based Pharmacokinetic
           Modeling to Characterize Enoxaparin Disposition in Children With Obesity

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      Authors: Jacqueline G. Gerhart; Fernando O. Carreño, Matthew Shane Loop, Craig R. Lee, Andrea N. Edginton, Jaydeep Sinha, Karan R. Kumar, Carl M. Kirkpatrick, Christoph P. Hornik, Daniel Gonzalez, on behalf of the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, Daniel K. Benjamin Jr, Kanecia Zimmerman, Phyllis Kennel, Rose Beci, Chi Dang Hornik, Gregory L. Kearns, Matthew Laughon, Ian M. Paul, Janice Sullivan, Kelly Wade, Paula Delmore, Perdita Taylor‐Zapata, June Lee, Thomas Green, Andrew Atz, Leslie Lenert, John Clark, Kalyan Chundru, Catherine Bendel, Brian Harvey, Sonya Grillo, Francis Chan, Stephanie Fan, Lorma Linda, Kevin Downes, Robert Grundmeier, Mark Ramos, Shawn O’Connor, Benjamin Fogel, Debbie Gipson, Samara Attala, Richard Eickstadt, Erin Kaleba, Don Liamini, Jamie Estill, Jeremy Jared, Peter Bow, Matt Laughon, Jennifer Talbert, Cindy Clark, Michael Miller, William Muller, Michael Smith, Janice Sullivan, Steve Heilman, KP Singh, Satish Vuyyuri, Jeff Schwitters, Don Stone
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-18T07:38:06-07:00
      DOI: 10.1002/cpt.2618
       
  • Opportunities and Challenges for Decentralized Clinical Trials: European
           Regulators’ Perspective

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      Authors: Amos J. Jong; Tessa I. Rijssel, Mira G. P. Zuidgeest, Ghislaine J. M. W. Thiel, Scott Askin, Jaime Fons‐Martínez, Tim De Smedt, Anthonius Boer, Yared Santa‐Ana‐Tellez, Helga Gardarsdottir, on behalf of the Trials@Home Consortium
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-17T12:13:54-07:00
      DOI: 10.1002/cpt.2628
       
  • Exposure‐Response Modeling and Simulation to Support Human Dosing of
           Botulism Antitoxin Heptavalent Product

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      Authors: Martin Beliveau; Deborah Anderson, Doug Barker, Shantha Kodihalli, Emilie Simard, Christine Hall, Jason S. Richardson
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-16T08:49:48-07:00
      DOI: 10.1002/cpt.2620
       
  • Impact of Obesity on Postprandial Triglyceride Contribution to Glucose
           Homeostasis, Assessed with a Semimechanistic Model

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      Authors: Jennifer Leohr; Maria C. Kjellsson
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-15T11:18:06-07:00
      DOI: 10.1002/cpt.2604
       
  • Transporters in drug development: International transporter consortium
           update on emerging transporters of clinical importance

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      Authors: Maciej J. Zamek‐Gliszczynski; Vishal Sangha, Hong Shen, Bo Feng, Matthias B. Wittwer, Manthena V. S. Varma, Xiaomin Liang, Yuichi Sugiyama, Lei Zhang, Reina Bendayan, The International Transporter Consortium
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-13T09:04:32-07:00
      DOI: 10.1002/cpt.2644
       
  • Clinical implications of altered drug transporter abundance/function and
           PBPK modeling in specific populations: An ITC perspective

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      Authors: Xiaoyan Chu; Bhagwat Prasad, Sibylle Neuhoff, Kenta Yoshida, J. Steven Leeder, Dwaipayan Mukherjee, Kunal Taskar, Manthena V. Varma, Xinyuan Zhang, Xinning Yang, Aleksandra Galetin
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-05-13T08:08:35-07:00
      DOI: 10.1002/cpt.2643
       
  • Clinical Pharmacology of Radiotheranostics in Oncology

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      Authors: Erik T. te Beek; Jacobus Burggraaf, Jaap J. M. Teunissen, Dennis Vriens
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-10T02:07:05-07:00
      DOI: 10.1002/cpt.2598
       
  • Evaluation of the Effect of Abrocitinib on Drug Transporters by Integrated
           Use of Probe Drugs and Endogenous Biomarkers

    • Free pre-print version: Loading...

      Authors: Manoli Vourvahis; Wonkyung Byon, Cheng Chang, Vu Le, Annette Diehl, Daniela Graham, Sakambari Tripathy, Nancy Raha, Lina Luo, Sumathy Mathialagan, Martin Dowty, A. David Rodrigues, Bimal Malhotra
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-09T01:58:40-07:00
      DOI: 10.1002/cpt.2594
       
  • Effect of a Ketohexokinase Inhibitor (PF‐06835919) on In Vivo OATP1B
           Activity: Integrative Risk Assessment Using Endogenous Biomarker and a
           Probe Drug

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      Authors: David A. Tess; Emi Kimoto, Amanda King‐Ahmad, Manoli Vourvahis, A. David Rodrigues, Arthur Bergman, Ruolun Qui, Veena Somayaji, Yan Weng, Kari R. Fonseca, John Litchfield, Manthena V. S. Varma
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-09T01:00:22-07:00
      DOI: 10.1002/cpt.2593
       
  • The Effect of Ibuprofen Exposure and Patient Characteristics on the
           Closure of the Patent Ductus Arteriosus in Preterm Infants

    • Free pre-print version: Loading...

      Authors: Aline G. J. Engbers; Swantje Völler, Robert B. Flint, Sebastiaan C. Goulooze, Johan Klerk, Elke H. J. Krekels, Monique Dijk, Sten P. Willemsen, Irwin K. M. Reiss, Catherijne A. J. Knibbe, Sinno H. P. Simons
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-06T11:48:11-07:00
      DOI: 10.1002/cpt.2616
       
  • Science‐Based Approach to Harmonize Contraception Recommendations in
           Clinical Trials and Pharmaceutical Labels

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      Authors: Christopher J. Bowman; Nathalie Becourt‐Lhote, Virginie Boulifard, Rüdiger Cordts, Solange Corriol‐Rohou, Brian Enright, Linda Erkman, Jayne Harris, Andreas Hartmann, Jan Hilpert, Sophie Kervyn, Britta Mattson, LaRonda Morford, Mireille Muller, Marcy Powell, Zhanna Sobol, Rajamuthu Srinivasan, Claudia Stark, Kary E. Thompson, Katie J. Turner, Paul Barrow
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-05T11:15:08-07:00
      DOI: 10.1002/cpt.2602
       
  • The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of
           Phenytoin and (S)‐Warfarin

    • Free pre-print version: Loading...

      Authors: Maor Wanounou; Chanan Shaul, Zahi Abu Ghosh, Shoshana Alamia, Yoseph Caraco
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-05T03:02:57-07:00
      DOI: 10.1002/cpt.2613
       
  • Managing Potential Drug Interactions of Nirmatrelvir/Ritonavir in
           COVID‐19 Patients: A Perspective from an Israeli Cross‐Sector
           Collaboration

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      Authors: Shiri Guy‐Alfandary; Sasha Zhurat, Maya Berlin, Tal De Haan, Itai Gueta, Renata Shihmanter, Ahuva Golik, Matitiahu Berkovitch, Sara Eyal, Lee H. Goldstein
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-05T01:59:58-07:00
      DOI: 10.1002/cpt.2610
       
  • Innovative Randomized Phase I Study and Dosing Regimen Selection to
           Accelerate and Inform Pivotal COVID‐19 Trial of Nirmatrelvir

    • Free pre-print version: Loading...

      Authors: Ravi Shankar P. Singh; Sima S. Toussi, Frances Hackman, Phylinda L. Chan, Rohit Rao, Richard Allen, Lien Van Eyck, Sylvester Pawlak, Eugene P. Kadar, Frances Clark, Haihong Shi, Annaliesa S. Anderson, Michael Binks, Sandeep Menon, Gianluca Nucci, Arthur Bergman
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-04T03:25:51-07:00
      DOI: 10.1002/cpt.2603
       
  • Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A
           Note of Caution Based on a Large Prospective Clinical Study

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      Authors: Mirjam With; Jonathan Knikman, Femke M. Man, Carin A. T. C. Lunenburg, Linda M. Henricks, André B. P. Kuilenburg, Jan G. Maring, Maurice C. Staveren, Niels Vries, Hilde Rosing, Jos H. Beijnen, Dick Pluim, Anil Modak, Alex L. T. Imholz, Ron H. N. Schaik, Jan H. M. Schellens, Hans Gelderblom, Annemieke Cats, Henk‐Jan Guchelaar, Ron H. J. Mathijssen, Jesse J. Swen, Didier Meulendijks
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-04T03:22:05-07:00
      DOI: 10.1002/cpt.2608
       
  • A Randomized, Single Ascending Dose Study to Assess the Safety,
           Tolerability, Pharmacokinetics, and Pharmacodynamics of a Novel Insulin
           Dimer

    • Free pre-print version: Loading...

      Authors: Geoffrey A. Walford; Kelly E. Duncan, Moises Hernandez, Pavan Vaddady, Marcus Hompesch, Linda Morrow, S. Aubrey Stoch
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-03T10:43:48-07:00
      DOI: 10.1002/cpt.2607
       
  • Immune Checkpoint Inhibitors and Venous Thromboembolism: An Analysis of
           the WHO Pharmacovigilance Database

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      Authors: Marion Allouchery; Clément Beuvon, Marie‐Christine Pérault‐Pochat, Pascal Roblot, Mathieu Puyade, Mickaël Martin
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-02T12:18:31-07:00
      DOI: 10.1002/cpt.2615
       
  • Real‐World Data on the Risk of Ventricular Arrhythmias with
           Sulfonamides

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      Authors: Alexandre O. Gérard; Diane Merino, Milou‐Daniel Drici
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-02T11:08:02-07:00
      DOI: 10.1002/cpt.2617
       
  • Effectiveness and Safety of Extended Oral Anticoagulant Therapy in
           Patients with Venous Thromboembolism: A Retrospective Cohort Study

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      Authors: Hye‐Rim Kang; Wei‐Hsuan Lo‐Ciganic, Christina E. DeRemer, Eric A. Dietrich, Pei‐Lin Huang, Haesuk Park
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-02T10:54:41-07:00
      DOI: 10.1002/cpt.2611
       
  • Biomarker Qualification at the European Medicines Agency: A Look Under the
           Hood

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      Authors: Steven Berman; Jeffrey Siegel
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-02T03:02:35-07:00
      DOI: 10.1002/cpt.2609
       
  • Impact of the ABCD‐GENE Score on Clopidogrel Clinical Effectiveness
           after PCI: A Multi‐Site, Real‐World Investigation

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      Authors: Cameron D. Thomas; Francesco Franchi, Ellen C. Keeley, Joseph S. Rossi, Marshall Winget, R. David Anderson, Alyssa L. Dempsey, Yan Gong, Megan N. Gower, Richard A. Kerensky, Natasha Kulick, Jean G. Malave, Caitrin W. McDonough, Ian R. Mulrenin, Petr Starostik, Amber L. Beitelshees, Julie A. Johnson, George A. Stouffer, Almut G. Winterstein, Dominick J. Angiolillo, Craig R. Lee, Larisa H. Cavallari
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-05-02T01:48:43-07:00
      DOI: 10.1002/cpt.2612
       
  • Contextualized drug‐drug interaction management improves clinical
           utility compared to basic drug‐drug interaction management in
           hospitalized patients

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      Authors: Arthur T.M. Wasylewicz; Britt W.M. Burgt, Thomas Manten, Marieke Kerskes, Wilma N. Compagner, Erik Korsten, Toine C.G. Egberts, Rene J.E. Grouls
      Abstract: Clinical Pharmacology & Therapeutics, Accepted Article.
      PubDate: 2022-04-29T12:00:00-07:00
      DOI: 10.1002/cpt.2624
       
  • The Current Landscape and Emerging Applications for Real‐World Data in
           Diagnostics and Clinical Decision Support and its Impact on Regulatory
           Decision Making

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      Authors: Elodie Baumfeld Andre; Nate Carrington, Flora S. Siami, Jo Carol Hiatt, Carly McWilliams, Carolyn Hiller, Andy Surinach, Alejandro Zamorano, Chris L. Pashos, Wade L. Schulz
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-29T10:48:54-07:00
      DOI: 10.1002/cpt.2565
       
  • Exposure‐Response Characterization of Tofacitinib Efficacy in Moderate
           to Severe Ulcerative Colitis: Results From Phase II and Phase III
           Induction and Maintenance Studies

    • Free pre-print version: Loading...

      Authors: Arnab Mukherjee; Shinichi Tsuchiwata, Timothy Nicholas, Jack A. Cook, Irene Modesto, Chinyu Su, Geert R. D’Haens, William J. Sandborn
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-27T12:00:00-07:00
      DOI: 10.1002/cpt.2601
       
  • How to Successfully Generate an Alternative Approach to a Thorough QT
           Study: GLPG1972 as an Example

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      Authors: Claudia Meyer; Ines Dierick, Glenn Gauderat, Jurgen Langenhorst, Céline Sarr, Emilie Leroux, Marylore Chenel, Sylvain Fouliard, Paul Passier
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-27T02:58:39-07:00
      DOI: 10.1002/cpt.2596
       
  • Physiologically‐Based Pharmacokinetic Modelling to Investigate
           Baricitinib and Tofacitinib Dosing Recommendations for COVID‐19 in
           Geriatrics

    • Free pre-print version: Loading...

      Authors: Ziteng Wang; Eric Chun Yong Chan
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-27T01:29:12-07:00
      DOI: 10.1002/cpt.2600
       
  • Givosiran Likely Inhibits Cytochrome P450 More Substantially Than Reported

    • Free pre-print version: Loading...

      Authors: Sander Bins; Eliane Sardh, Janneke G. Langendonk
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-21T12:43:39-07:00
      DOI: 10.1002/cpt.2597
       
  • Asia‐Inclusive Clinical Research and Development Enabled by
           Translational Science and Quantitative Clinical Pharmacology: Toward a
           Culture That Challenges the Status Quo

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      Authors: Karthik Venkatakrishnan; Neeraj Gupta, Patrick F. Smith, Tiffany Lin, Neil Lineberry, Tatiana Ishida, Lin Wang, Mark Rogge
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-17T10:58:57-07:00
      DOI: 10.1002/cpt.2591
       
  • Inflammation, Lifestyle Factors, and the Microbiome‐Gut‐Brain Axis:
           Relevance to Depression and Antidepressant Action

    • Free pre-print version: Loading...

      Authors: Francisco Donoso; John F. Cryan, Loreto Olavarría‐Ramírez, Yvonne M. Nolan, Gerard Clarke
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-04-05T12:00:00-07:00
      DOI: 10.1002/cpt.2581
       
  • Estimands and Complex Innovative Designs

    • Free pre-print version: Loading...

      Authors: Olivier Collignon; Anja Schiel, Carl‐Fredrik Burman, Kaspar Rufibach, Martin Posch, Frank Bretz
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-03-29T12:00:00-07:00
      DOI: 10.1002/cpt.2575
       
  • PharmVar GeneFocus: CYP3A5

    • Free pre-print version: Loading...

      Authors: Cristina Rodriguez‐Antona; Jessica L. Savieo, Volker M. Lauschke, Katrin Sangkuhl, Britt I. Drögemöller, Danxin Wang, Ron H. N. Schaik, Andrei A. Gilep, Arul P. Peter, Erin C. Boone, Bronwyn E. Ramey, Teri E. Klein, Michelle Whirl‐Carrillo, Victoria M. Pratt, Andrea Gaedigk
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-03-29T12:00:00-07:00
      DOI: 10.1002/cpt.2563
       
  • In Vivo Cellular Expansion of Lisocabtagene Maraleucel and Association
           With Efficacy and Safety in Relapsed/Refractory Large B‐Cell Lymphoma

    • Free pre-print version: Loading...

      Authors: Ken Ogasawara; James Lymp, Timothy Mack, Justine Dell’Aringa, Chang‐pin Huang, Jeff Smith, Leanne Peiser, Ana Kostic
      Abstract: Clinical Pharmacology & Therapeutics, EarlyView.
      PubDate: 2022-03-20T08:24:36-07:00
      DOI: 10.1002/cpt.2561
       
 
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