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Toxicology Research
Journal Prestige (SJR): 0.537

Citation Impact (citeScore): 2
Number of Followers: 8

Partially Free Journal
ISSN (Print) 2045-452X - ISSN (Online) 2045-4538
Published by Oxford University Press

[425 journals]

The protective effect of thymoquinone on tert-butylhydroquinone induced
cytotoxicity in human umbilical vein endothelial cells
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  Authors: Zahra Karimi; Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00235A, PaperZahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
  2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.
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  The content of this RSS Feed (c) The Royal Society of Chemistry
Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma
cells through necroptosis induction
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  Authors: Yuexiang Niu; Engong Tang, Qingan Zhang
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00240E, PaperYuexiang Niu, Engong Tang, Qingan Zhang
  Hepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.
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Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae
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  Authors: Abhishek Raj; Vasanthi Nachiappan
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00139E, PaperAbhishek Raj, Vasanthi Nachiappan
  BQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.
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Phytochemicals protect L02 cells against hepatotoxicity induced by emodin
via the Nrf2 signaling pathway
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  Authors: Yan Yan; Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00220K, PaperYan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
  Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.
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Application of the direct peptide reactivity assay (DPRA) to inorganic
compounds: a case study of platinum species
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  Authors: Jocelyn D. C. Hemming; Mark Hosford, Martin M. Shafer
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00242A, PaperJocelyn D. C. Hemming, Mark Hosford, Martin M. Shafer
  The in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.
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Nanoparticle induced barrier function assessment at liquid–liquid and
air–liquid interface in novel human lung epithelia cell lines
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  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00179D, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
  To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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Astaxanthin reduces perfluorooctanoic acid cytotoxicity in Saccharomyces
cerevisiae
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  Authors: S. J. Sudharshan; Raghavendra Tirupathi, Madhu Dyavaiah
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00215D, PaperS. J. Sudharshan, Raghavendra Tirupathi, Madhu Dyavaiah
  Perfluorooctanoic acid (PFA) has been identified as an environmental contaminant of high concern for human health.
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Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the
TLR4/MyD88/NF-κB pathway
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  Authors: Jing Li; Zhaowei Gu, Yue Liu, Yu Wang, Min Zhao
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00222G, PaperJing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min Zhao
  Ischemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.
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Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic
injuries by regulation of genes in rats
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  Authors: Jawaid Ahmed Zai; Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash Zahra
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00157C, PaperJawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash Zahra
  Alteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.
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Effects of moderate red wine on cardiovascular risk factors in diabetics:
a systematic review and meta-analysis of randomized controlled trials
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  Authors: Saavia Alice Naame; Decheng Li, Ruixue Huang
  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00227H, PaperSaavia Alice Naame, Decheng Li, Ruixue Huang
  Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
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Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a
reduced sensitivity to cisplatin-induced testicular germ cell apoptosis
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  Abstract: Toxicol. Res., 2019, Advance Article
  
  DOI : 10.1039/C9TX00142E, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rashin Ghaffari, John H. Richburg
  Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
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Novel Evaluation of Sevoflurane Anesthetics Exposure on the Testicular
Germ Cells of Neonatal Male Mice
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  Authors: Alireza Ebrahim Soltani; Abdol-Mohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
  Abstract: Toxicol. Res., 2019, Accepted Manuscript
  
  DOI : 10.1039/C9TX00193J, PaperAlireza Ebrahim Soltani , Abdol-Mohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
  Background: Inhalatory anesthetics may be impact on spermatogenesis and sexual behavior. Vast number of consideration should conduct to screen the effect of inhalatory anesthetics on the sperm and semen quality....
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Cadmium telluride quantum dots-exposed human bronchial epithelial cells: a
further study of the cellular response by proteomics
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  Authors: Yan-Ming Xu; Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
  Abstract: Toxicol. Res., 2019, Accepted Manuscript
  
  DOI : 10.1039/C9TX00126C, PaperYan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
  Quantum dots (QDs) are luminescent nanoparticles with superior versatility. In this regard, the cadmium telluride (CdTe) QDs have been widely used for various bioimaging applications. Although these nano-Cd containing particles...
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Cigarette smoke inhalation aggravates diabetic kidney injury in rats
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  Authors: Songling Jiang; Do Van Quan, Jae Hyuck Sung, Moo-Yeol Lee, Hunjoo Ha
  Abstract: Toxicol. Res., 2019, 8,964-971
  
  DOI : 10.1039/C9TX00201D, PaperSongling Jiang, Do Van Quan, Jae Hyuck Sung, Moo-Yeol Lee, Hunjoo Ha
  Four weeks of exposure to cigarette smoke aggravated the progression of diabetic kidney injury including inflammation, fibrosis, and oxidative stress.
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Innovative models for in vitro detection of seizure
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  Authors: Kimberly L. Rockley; Ruth A. Roberts, Michael J. Morton
  Abstract: Toxicol. Res., 2019, 8,784-788
  
  DOI : 10.1039/C9TX00210C, Review ArticleKimberly L. Rockley, Ruth A. Roberts, Michael J. Morton
  New technologies offer the opportunity to screen for seizure liability in vitro, avoiding costly failures in preclinical and clinical development.
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Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity,
genotoxicity and pro-inflammatory mediators induced by hydroxyapatite
nanoparticles in male rats
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  Authors: Israa F. Mosa; Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
  Abstract: Toxicol. Res., 2019, 8,939-952
  
  DOI : 10.1039/C9TX00221A, PaperIsraa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
  Due to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.
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Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects
on human umbilical vein endothelial cells, normal human fibroblasts,
HEPG2, and Galleria mellonella
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  Authors: Cristiane Angélica Ottoni; Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
  Abstract: Toxicol. Res., 2019, 8,789-801
  
  DOI : 10.1039/C9TX00091G, PaperCristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
  Biogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a
perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L.
A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege,
Toxicol. Res., 2019, 8, DOI: 10.1039/C9TX00158A
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  Abstract: Toxicol. Res., 2019, 8,1059-1059
  
  DOI : 10.1039/C9TX00216B, Comment Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.D. Nicholas Bateman, James W. Dear
  Mullins et al. made a comment on our article (
  DOI : 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Environmental distribution of the neurotoxin L-BMAA in Paenibacillus
species
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  Authors: Peter B. Nunn; Geoffrey A. Codd
  Abstract: Toxicol. Res., 2019, 8,781-783
  
  DOI : 10.1039/C9TX00203K, ViewpointPeter B. Nunn, Geoffrey A. Codd
  The neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Thyroid endocrine status and biochemical stress responses in adult male
Wistar rats chronically exposed to pristine polystyrene nanoplastics
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  Authors: Fatemeh Amereh; Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
  Abstract: Toxicol. Res., 2019, 8,953-963
  
  DOI : 10.1039/C9TX00147F, PaperFatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
  At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction
by suppressing mitochondrial reactive oxidative stress
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  Authors: Li Pang; Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
  Abstract: Toxicol. Res., 2019, 8,918-927
  
  DOI : 10.1039/C9TX00186G, PaperLi Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
  α-Lipoic acid antagonizes paraquat toxicity.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Gynura divaricata ameliorates hepatic insulin resistance by modulating
insulin signalling, maintaining glycolipid homeostasis and reducing
inflammation in type 2 diabetic mice
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  Authors: Xuan Dong; Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
  Abstract: Toxicol. Res., 2019, 8,928-938
  
  DOI : 10.1039/C9TX00191C, PaperXuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
  Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Ex vivo toxicological evaluation of experimental anticancer gold(I)
complexes with lansoprazole-type ligands
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  Authors: Natalia Estrada-Ortiz; Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela Casini
  Abstract: Toxicol. Res., 2019, 8,885-895
  
  DOI : 10.1039/C9TX00149B, PaperNatalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela Casini
  Novel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.
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Characteristic synergistic cytotoxic effects toward cells in graphene
oxide dressing with cadmium and copper ions
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  Authors: Yiyang Dong; Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
  Abstract: Toxicol. Res., 2019, 8,908-917
  
  DOI : 10.1039/C9TX00146H, PaperYiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
  Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45
years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8,
489
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  Authors: Michael E. Mullins; Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. Holstege
  Abstract: Toxicol. Res., 2019, 8,1057-1058
  
  DOI : 10.1039/C9TX00158A, CommentMichael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. Holstege
  We point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA
damage induced by etoposide in peripheral blood mononuclear cells
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  Authors: Magdalena Kluska; Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna Woźniak
  Abstract: Toxicol. Res., 2019, 8,896-907
  
  DOI : 10.1039/C9TX00176J, PaperMagdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna Woźniak
  Bioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.
  The content of this RSS Feed (c) The Royal Society of Chemistry
miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by
targeting the VEGFA/14-3-3γ signal pathway
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  Authors: Xuan-Ying Chen; Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
  Abstract: Toxicol. Res., 2019, 8,875-884
  
  DOI : 10.1039/C9TX00100J, PaperXuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
  Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Tin thiocarbonohydrazone complexes: synthesis, crystal structures and
biological evaluation
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  Authors: Jin Wang; Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue Li
  Abstract: Toxicol. Res., 2019, 8,862-867
  
  DOI : 10.1039/C9TX00109C, PaperJin Wang, Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue Li
  Three organotin thiocarbonohydrazone complexes have been synthesized, and growth inhibition assays indicated that complex 3 has the highest tumor cell selectivity.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double
shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese
hamster ovary cells
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  Authors: Neo Mervyn Monaheng; Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
  Abstract: Toxicol. Res., 2019, 8,868-874
  
  DOI : 10.1039/C9TX00113A, PaperNeo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
  In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Integrated network pharmacology and targeted metabolomics to reveal the
mechanism of nephrotoxicity of triptolide
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  Authors: Wei Huang; Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
  Abstract: Toxicol. Res., 2019, 8,850-861
  
  DOI : 10.1039/C9TX00067D, PaperWei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
  Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
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Prometryn induces apoptotic cell death through cell cycle arrest and
oxidative DNA damage
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  Authors: Qiaoyun Liu; Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
  Abstract: Toxicol. Res., 2019, 8,833-841
  
  DOI : 10.1039/C9TX00080A, PaperQiaoyun Liu, Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
  Prometryn induces oxidative stress-mediated DNA damage; Prometryn induces S phase of cell cycle arrest; Prometryn induces Bax-dependent apoptosis in BEAS-2B cells.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Serum miRNAs are differentially altered by ethanol and caffeine
consumption in rats
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  Authors: M. Martinez; I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
  Abstract: Toxicol. Res., 2019, 8,842-849
  
  DOI : 10.1039/C9TX00069K, PaperM. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
  Alcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.
  The content of this RSS Feed (c) The Royal Society of Chemistry
The chronic effect of amorphous silica nanoparticles and benzo[a]pyrene
co-exposure at low dose in human bronchial epithelial BEAS-2B cells
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  Authors: Jing Wu; Jie Zhang, Jihua Nie, Junchao Duan, Yanfeng Shi, Lin Feng, Xiaozhe Yang, Yan An, Zhiwei Sun
  Abstract: Toxicol. Res., 2019, 8,731-740
  
  DOI : 10.1039/C9TX00112C, PaperJing Wu, Jie Zhang, Jihua Nie, Junchao Duan, Yanfeng Shi, Lin Feng, Xiaozhe Yang, Yan An, Zhiwei Sun
  As the main components of fine particulate matter (PM2.5), silica nanoparticles (SiNPs) and benzo[a]pyrene (B[a]P) have attracted increasing attention recently.
  The content of this RSS Feed (c) The Royal Society of Chemistry
High-throughput transcriptome sequencing reveals extremely high doses of
ionizing radiation-response genes in Caenorhabditis elegans
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  Authors: Youqin Xu; Lina Chen, Mengyi Liu, Yanfang Lu, Yanwei Yue, Yue Liu, Honghao Chen, Fuliang Xie, Chao Zhang
  Abstract: Toxicol. Res., 2019, 8,754-766
  
  DOI : 10.1039/C9TX00101H, PaperYouqin Xu, Lina Chen, Mengyi Liu, Yanfang Lu, Yanwei Yue, Yue Liu, Honghao Chen, Fuliang Xie, Chao Zhang
  This study sought novel ionizing radiation-response (IR-response) genes in Caenorhabditis elegans (C. elegans).
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Celastrol pretreatment as a therapeutic option against cisplatin-induced
nephrotoxicity
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  Authors: Tugce Boran; Aysenur Gunaydin, Ayse Tarbin Jannuzzi, Eren Ozcagli, Buket Alpertunga
  Abstract: Toxicol. Res., 2019, 8,723-730
  
  DOI : 10.1039/C9TX00141G, PaperTugce Boran, Aysenur Gunaydin, Ayse Tarbin Jannuzzi, Eren Ozcagli, Buket Alpertunga
  Celastrol is a natural bioactive compound extracted from the medicinal plant Tripterygium wilfordii Hook F.
  The content of this RSS Feed (c) The Royal Society of Chemistry
The protective role of CsNPs and CurNPs against DNA damage, oxidative
stress, and histopathological and immunohistochemical alterations induced
by hydroxyapatite nanoparticles in male rat kidney
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  Authors: Israa F. Mosa; Mokhtar I. Yousef, Maher Kamel, Osama F. Mosa, Yasser Helmy
  Abstract: Toxicol. Res., 2019, 8,741-753
  
  DOI : 10.1039/C9TX00138G, PaperIsraa F. Mosa, Mokhtar I. Yousef, Maher Kamel, Osama F. Mosa, Yasser Helmy
  Hydroxyapatite nanoparticles (HAP-NPs) are an inorganic component of natural bone that are mainly used in tissue engineering field due to their bioactivity, osteoconductivity, biocompatibility, non-inflammatory, and non-toxicity properties.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Methods for the analysis of transcriptome dynamics
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  Authors: Daniela F. Rodrigues; Vera M. Costa, Ricardo Silvestre, Maria L. Bastos, Félix Carvalho
  Abstract: Toxicol. Res., 2019, 8,597-612
  
  DOI : 10.1039/C9TX00088G, Review ArticleDaniela F. Rodrigues, Vera M. Costa, Ricardo Silvestre, Maria L. Bastos, Félix Carvalho
  Transcriptome analysis by recognizing the relative contribution of RNA synthesis and decay to RNA levels is essential to understand the regulatory mechanisms associated with gene expression alterations.
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Generation of TD50 values for carcinogenicity study data
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  Authors: Andrew Thresher; John Paul Gosling, Richard Williams
  Abstract: Toxicol. Res., 2019, 8,696-703
  
  DOI : 10.1039/C9TX00118B, PaperAndrew Thresher, John Paul Gosling, Richard Williams
  A reproducible methodology for modelling TD50 values for carcinogenic potency and its applicability given the commonly available data.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Study of mitochondrial swelling, membrane fluidity and ROS production
induced by nano-TiO2 and prevented by Fe incorporation
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  Authors: Tejal Barkhade; Santosh Kumar Mahapatra, Indrani Banerjee
  Abstract: Toxicol. Res., 2019, 8,711-722
  
  DOI : 10.1039/C9TX00143C, PaperTejal Barkhade, Santosh Kumar Mahapatra, Indrani Banerjee
  The potential impact of TiO2 and Fe incorporated TiO2 nanoparticles at the organelle level has been reported.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Benzisothiazolinone upregulates the MUC5AC expression via ERK1/2, p38, and
NF-κB pathways in airway epithelial cells
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  Authors: Soyoung Kwak; Yoon Seok Choi, Hyung Gyun Na, Chang Hoon Bae, Si-Youn Song, Hyung Geun Kim, Yong-Dae Kim
  Abstract: Toxicol. Res., 2019, 8,704-710
  
  DOI : 10.1039/C9TX00135B, PaperSoyoung Kwak, Yoon Seok Choi, Hyung Gyun Na, Chang Hoon Bae, Si-Youn Song, Hyung Geun Kim, Yong-Dae Kim
  BIT may be involved in mucus hypersecretion associated with airway inflammatory diseases.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Acute and 30-day oral toxicity studies of a novel coccidiostat –
ethanamizuril
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  Authors: Wenlong Xiao; Xiaoyang Wang, Chunmei Wang, Mi Wang, Chenzhong Fei, Lifang Zhang, Feiqun Xue, Guoyong Wang, Keyu Zhang
  Abstract: Toxicol. Res., 2019, 8,686-695
  
  DOI : 10.1039/C9TX00073A, PaperWenlong Xiao, Xiaoyang Wang, Chunmei Wang, Mi Wang, Chenzhong Fei, Lifang Zhang, Feiqun Xue, Guoyong Wang, Keyu Zhang
  Ethanamizuril is a novel triazine compound that exhibits remarkable anticoccidial activity.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Hepatoprotective activity of raspberry ketone is mediated via inhibition
of the NF-κB/TNF-α/caspase axis and mitochondrial apoptosis in
chemically induced acute liver injury
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  Authors: Dalia Fouad; Amira Badr, Hala A. Attia
  Abstract: Toxicol. Res., 2019, 8,663-676
  
  DOI : 10.1039/C9TX00068B, PaperDalia Fouad, Amira Badr, Hala A. Attia
  Possible proposed mechanisms of hepatoprotective activity of raspberry ketone. Raspberry ketone ameliorated hepatic oxidative stress and suppressed inflammation, apoptosis, and DNA fragmentation in CCl4-injured hepatocytes.
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Association of smoking with coronary artery disease in Nepalese
populations: a case control study
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  Authors: Til Bahadur Basnet; Cheng Xu, Manthar Ali Mallah, Wiwik Indayati, Cheng Shi, Jin Xu, Aihua Gu
  Abstract: Toxicol. Res., 2019, 8,677-685
  
  DOI : 10.1039/C9TX00083F, PaperTil Bahadur Basnet, Cheng Xu, Manthar Ali Mallah, Wiwik Indayati, Cheng Shi, Jin Xu, Aihua Gu
  There are well-known traditional risk factors for coronary artery disease (CAD).
  The content of this RSS Feed (c) The Royal Society of Chemistry
Toxicity of combined exposure of ZnO nanoparticles (NPs) and myricetin to
Caco-2 cells: changes of NP colloidal aspects, NP internalization and the
apoptosis-endoplasmic reticulum stress pathway
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  Authors: Chaohua Wu; Yunfeng Luo, Liangliang Liu, Yixi Xie, Yi Cao
  Abstract: Toxicol. Res., 2019, 8,613-620
  
  DOI : 10.1039/C9TX00127A, PaperChaohua Wu, Yunfeng Luo, Liangliang Liu, Yixi Xie, Yi Cao
  Phytochemicals as typical food components may significantly influence the toxicity of nanoparticles (NPs) in intestinal cells, indicating a need to evaluate the toxicological effects of NPs in a complex situation.
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Inhibitions of HMGB1 and TLR4 alleviate DINP-induced asthma in mice
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  Authors: Yun-Ho Hwang; Yongjin Lee, Man-Jeong Paik, Sung-Tae Yee
  Abstract: Toxicol. Res., 2019, 8,621-629
  
  DOI : 10.1039/C9TX00048H, PaperYun-Ho Hwang, Yongjin Lee, Man-Jeong Paik, Sung-Tae Yee
  We studied the effects of high mobility group box chromosomal protein 1 (HMGB1) and toll-like receptor (TLR4) in diisonoyl phthalate (DINP)-induced asthma.
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Protective effects of zinc oxide nanoparticles against doxorubicin induced
testicular toxicity and DNA damage in male rats
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  Authors: Zeynab Khamis El-Maddawy; Walaa Slouma Hamouda Abd El Naby
  Abstract: Toxicol. Res., 2019, 8,654-662
  
  DOI : 10.1039/C9TX00052F, PaperZeynab Khamis El-Maddawy, Walaa Slouma Hamouda Abd El Naby
  The present study aims to investigate the protective effects of zinc oxide nanoparticles (ZnO NPs) on doxorubicin-induced testicular injury.
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TrxR2 overexpression alleviates inflammation-mediated neuronal death via
reducing the oxidative stress and activating the Akt–Parkin pathway
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  Authors: Jinbao Gao; Yunjun Li, Wende Li, Haijiang Wang
  Abstract: Toxicol. Res., 2019, 8,641-653
  
  DOI : 10.1039/C9TX00076C, PaperJinbao Gao, Yunjun Li, Wende Li, Haijiang Wang
  Neuronal death caused by inflammatory cytokine-mediated neuroinflammation is being extensively explored.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Toxicity and multigenerational effects of bisphenol S exposure to
Caenorhabditis elegans on developmental, biochemical, reproductive and
oxidative stress
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  Authors: Xiang Xiao; Xiaowei Zhang, Caiqin Zhang, Jie Li, Yansheng Zhao, Ying Zhu, Jiayan Zhang, Xinghua Zhou
  Abstract: Toxicol. Res., 2019, 8,630-640
  
  DOI : 10.1039/C9TX00055K, PaperXiang Xiao, Xiaowei Zhang, Caiqin Zhang, Jie Li, Yansheng Zhao, Ying Zhu, Jiayan Zhang, Xinghua Zhou
  Bisphenol A (BPA) is a typical endocrine disruptor.
  The content of this RSS Feed (c) The Royal Society of Chemistry