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  Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
Showing 401 - 253 of 253 Journals sorted alphabetically
Microbial Drug Resistance     Hybrid Journal   (Followers: 3)
Molecular Informatics     Hybrid Journal   (Followers: 5)
Molecular Pharmacology     Hybrid Journal   (Followers: 2)
Molekul     Open Access   (Followers: 1)
Natural Product Communications     Open Access  
Nature Reviews Drug Discovery     Full-text available via subscription   (Followers: 310)
Naunyn-Schmiedeberg's Archives of Pharmacology     Hybrid Journal  
NeuroMolecular Medicine     Hybrid Journal  
Neuropharmacology     Hybrid Journal   (Followers: 5)
Neuropsychopharmacology     Hybrid Journal   (Followers: 17)
Neuropsychopharmacology Reports     Open Access  
Nigerian Journal of Natural Products and Medicine     Full-text available via subscription  
OA Drug Design & Delivery     Open Access  
OA Medical Hypothesis     Open Access  
Obesity Facts     Open Access   (Followers: 8)
Open Pharmacoeconomics & Health Economics Journal     Open Access   (Followers: 1)
Open Pharmacology Journal     Open Access  
OpenNano     Open Access   (Followers: 1)
Orbital - The Electronic Journal of Chemistry     Open Access   (Followers: 1)
Oriental Pharmacy and Experimental Medicine     Partially Free   (Followers: 2)
Pain and Therapy     Open Access   (Followers: 3)
Particulate Science and Technology: An International Journal     Hybrid Journal   (Followers: 1)
PDA Journal of Pharmaceutical Science and Technology     Full-text available via subscription   (Followers: 33)
Pediatric Drugs     Full-text available via subscription   (Followers: 3)
Pediatric Pharmacology     Open Access   (Followers: 1)
Pharmaceutica Analytica Acta     Open Access  
Pharmaceutical Biology     Open Access  
Pharmaceutical Care-La Farmacoterapia     Open Access  
Pharmaceutical Chemistry Journal     Hybrid Journal  
Pharmaceutical Development and Technology     Hybrid Journal   (Followers: 19)
Pharmaceutical Executive     Full-text available via subscription   (Followers: 2)
Pharmaceutical Fronts     Open Access   (Followers: 9)
Pharmaceutical Historian     Open Access  
Pharmaceutical Journal     Free   (Followers: 8)
Pharmaceutical Journal of Sri Lanka     Open Access  
Pharmaceutical Medicine     Full-text available via subscription   (Followers: 4)
Pharmaceutical Nanotechnology     Hybrid Journal  
Pharmaceutical Patent Analyst     Full-text available via subscription   (Followers: 3)
Pharmaceutical Research     Hybrid Journal   (Followers: 93)
Pharmaceutical Statistics     Hybrid Journal   (Followers: 15)
Pharmaceutical Technology     Full-text available via subscription   (Followers: 6)
Pharmaceuticals     Open Access   (Followers: 4)
Pharmacia     Open Access  
Pharmaciana     Open Access  
PharmacoEconomics     Full-text available via subscription   (Followers: 25)
PharmacoEconomics & Outcomes News     Full-text available via subscription   (Followers: 2)
PharmacoEconomics German Research Articles     Full-text available via subscription  
PharmacoEconomics Spanish Research Articles     Hybrid Journal   (Followers: 1)
Pharmacoepidemiology and Drug Safety     Hybrid Journal   (Followers: 33)
Pharmacogenetics and Genomics     Hybrid Journal   (Followers: 1)
Pharmacogenomics     Hybrid Journal   (Followers: 7)
Pharmacogenomics and Personalized Medicine     Open Access   (Followers: 2)
Pharmacogenomics Journal     Hybrid Journal   (Followers: 5)
Pharmacognosy Communications     Partially Free  
Pharmacognosy Magazine     Open Access   (Followers: 2)
Pharmacognosy Research     Open Access   (Followers: 2)
Pharmacological Reports     Hybrid Journal  
Pharmacological Research     Hybrid Journal   (Followers: 1)
Pharmacological Research - Modern Chinese Medicine     Open Access  
Pharmacological Reviews     Hybrid Journal   (Followers: 2)
Pharmacology     Full-text available via subscription  
Pharmacology & Therapeutics     Hybrid Journal   (Followers: 3)
Pharmacology & Pharmacy     Open Access   (Followers: 1)
Pharmacology Biochemistry and Behavior     Hybrid Journal   (Followers: 2)
Pharmacology Research & Perspectives     Open Access  
Pharmacon : Jurnal Farmasi Indonesia     Open Access  
Pharmacopsychiatry     Hybrid Journal   (Followers: 3)
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy     Hybrid Journal   (Followers: 37)
Pharmactuel     Open Access   (Followers: 1)
Pharmacy     Open Access   (Followers: 4)
Pharmacy & Pharmacology     Open Access   (Followers: 1)
Pharmacy Education     Full-text available via subscription   (Followers: 11)
Pharmacy Practice (Internet)     Open Access   (Followers: 8)
Pharmakon : Arzneimittel in Wissenschaft und Praxis     Full-text available via subscription   (Followers: 1)
PharmaNutrition     Hybrid Journal   (Followers: 3)
PharmaTutor     Open Access  
Pharmazeutische Industrie     Full-text available via subscription   (Followers: 9)
Pharmazeutische Zeitung     Full-text available via subscription   (Followers: 11)
Pharmazie in Unserer Zeit (Pharmuz)     Hybrid Journal   (Followers: 11)
Physiology International     Full-text available via subscription   (Followers: 3)
Plant Products Research Journal     Full-text available via subscription  
Planta Medica     Hybrid Journal   (Followers: 4)
Planta Medica International Open     Open Access  
Prescriber     Hybrid Journal   (Followers: 9)
Progress in Neuro-Psychopharmacology and Biological Psychiatry     Hybrid Journal   (Followers: 8)
Psychiatry and Clinical Psychopharmacology     Open Access   (Followers: 1)
Psychopharmacology     Hybrid Journal   (Followers: 15)
Pulmonary Pharmacology & Therapeutics     Hybrid Journal   (Followers: 2)
PZ Prisma : Materialien zur Fort- und Weiterbildung     Full-text available via subscription  
Redox Report     Open Access  
Regulatory Mechanisms in Biosystems     Open Access   (Followers: 1)
Regulatory Toxicology and Pharmacology     Hybrid Journal   (Followers: 41)
Research & Reviews : A Journal of Drug Design & Discovery     Full-text available via subscription  
Research & Reviews : A Journal of Pharmaceutical Science     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacognosy     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacology     Full-text available via subscription   (Followers: 1)
Research in Pharmaceutical Sciences     Open Access   (Followers: 3)
Research in Social and Administrative Pharmacy     Hybrid Journal   (Followers: 3)
Research Journal of Pharmacognosy     Open Access  
Research Results in Pharmacology     Open Access  
Reviews of Physiology, Biochemistry and Pharmacology     Hybrid Journal   (Followers: 4)
Reviews on Clinical Pharmacology and Drug Therapy     Full-text available via subscription  
Revista Colombiana de Ciencias Químico-Farmacéuticas     Open Access  
Revista Cubana de Plantas Medicinales     Open Access   (Followers: 1)
Revista de Ciências Farmacêuticas Básica e Aplicada     Open Access  
Revista Mexicana de Ciencias Farmaceuticas     Open Access  
Revue de Médecine et de Pharmacie     Full-text available via subscription  
Safety and Risk of Pharmacotherapy     Open Access   (Followers: 1)
Saudi Pharmaceutical Journal     Open Access  
Scandinavian Journal of Clinical and Laboratory Investigation     Hybrid Journal   (Followers: 7)
Scientia Pharmaceutica     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Oncology Nursing     Full-text available via subscription   (Followers: 10)
Separation Science plus (SSC plus)     Hybrid Journal  
Side Effects of Drugs Annual     Full-text available via subscription   (Followers: 2)
Skin Pharmacology and Physiology     Full-text available via subscription   (Followers: 6)
Substance Abuse : Research and Treatment     Open Access   (Followers: 5)
Suchttherapie     Hybrid Journal   (Followers: 1)
Sustainable Chemistry and Pharmacy     Full-text available via subscription   (Followers: 1)
Synfacts     Hybrid Journal   (Followers: 5)
SynOpen     Open Access  
The Botulinum J.     Hybrid Journal  
The Brown University Psychopharmacology Update     Hybrid Journal   (Followers: 2)
The Medical Letter     Full-text available via subscription   (Followers: 18)
The Pink Sheet     Full-text available via subscription   (Followers: 12)
The Pink Sheet Daily     Full-text available via subscription   (Followers: 4)
Therapeutic Advances in Drug Safety     Open Access   (Followers: 3)
Therapeutic Advances in Psychopharmacology     Open Access   (Followers: 4)
Therapeutic Advances in Vaccines     Hybrid Journal   (Followers: 1)
Therapeutic Drug Monitoring     Hybrid Journal   (Followers: 3)
Therapeutic Innovation & Regulatory Science     Hybrid Journal   (Followers: 7)
Thérapie     Full-text available via subscription   (Followers: 1)
TheScientist     Free   (Followers: 5)
Toxicological & Environmental Chemistry     Hybrid Journal   (Followers: 2)
Toxicological Research     Hybrid Journal  
Toxicological Sciences     Hybrid Journal   (Followers: 11)
Toxicology     Hybrid Journal   (Followers: 18)
Toxicology and Applied Pharmacology     Hybrid Journal   (Followers: 24)
Toxicology and Industrial Health     Hybrid Journal   (Followers: 6)
Toxicology in Vitro     Hybrid Journal   (Followers: 11)
Toxicology International     Full-text available via subscription   (Followers: 5)
Toxicology Letters     Hybrid Journal   (Followers: 15)
Toxicology Mechanisms and Methods     Hybrid Journal   (Followers: 7)
Toxicology Research     Partially Free   (Followers: 8)
Toxicon     Hybrid Journal   (Followers: 5)
Toxicon : X     Open Access  
Toxin Reviews     Hybrid Journal  
Translational Psychiatry     Open Access   (Followers: 14)
Trends in Peptide and Protein Sciences     Open Access  
Trends in Pharmacological Sciences     Full-text available via subscription   (Followers: 19)
Tropical Journal of Pharmaceutical Research     Open Access  
Ukrainian Biopharmaceutical Journal     Open Access  
Vascular Pharmacology     Hybrid Journal   (Followers: 2)
World Mycotoxin Journal     Hybrid Journal   (Followers: 3)
Yakugaku Zasshi     Open Access   (Followers: 1)
Zeitschrift für Phytotherapie     Hybrid Journal   (Followers: 1)
Актуальні питання фармацевтичної та медичної науки та практики     Open Access  
Фармацевтичний часопис     Open Access  

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Similar Journals
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Journal of Anaesthesiology Clinical Pharmacology
Journal Prestige (SJR): 0.612
Citation Impact (citeScore): 1
Number of Followers: 9  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0970-9185 - ISSN (Online) 2231-2730
Published by Wolters Kluwer Health Homepage  [4 journals]
  • Perioperative opioids: Are they indispensable'

    • Authors: Bhatia; Pradeep Kumar; Mohammed, Sadik
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Opioid sparing strategies for perioperative pain management other than
           regional anaesthesia: A narrative review

    • Authors: Ghai; Babita; Jafra, Anudeep; Bhatia, Nidhi; Chanana, Neha; Bansal, Dipika; Mehta, Vivek
      Abstract: Opioids play a crucial role in pain management in spite of causing increased hospital morbidity and related costs. It may also cause significant risks such as postoperative nausea and vomiting (PONV), sedation, sleep disturbances, urinary retention and respiratory depression (commonly referred to as opioid related adverse effects) in postoperative patients. In order to evade these opioid related side effects and also improve pain management, multimodal analgesia i.e., combination of different analgesics, was introduced more than a decade ago. Both pharmacological and non-pharmacological techniques are available as opioid sparing analgesia. Research from around the world have proved pharmacological techniques ranging from acetaminophen, NSAIDs (non-steroidal anti-inflammatory drugs), N-methyl-D-aspartate receptor antagonists (NDMA), alpha-2 agonists, anticonvulsants such as gamma aminobutyric acid analogues, beta-blockers, capsaicin, lignocaine infusion to glucocorticoids to be effective. On the other hand, non-pharmacological methods include techniques such as cognitive behavioral therapy, transcutaneous electrical nerve stimulation (TENS), electroanalgesia, acupuncture and hypnosis. However, research regarding the effect of these non-pharmacological techniques on pain management is still needed.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Artificial intelligence, nano-technology and genomic medicine: The future
           of anaesthesia

    • Authors: Naaz; Shagufta; Asghar, Adil
      Abstract: imageNanotechnology with artificial intelligence (AI) can metamorphose medicine to an extent that has never been achieved before. AI could be used in anesthesia to develop advanced clinical decision support tools based on machine learning, increasing efficiency, and accuracy. It is also potentially highly troublesome by creating insecurity among clinicians and allowing the transfer of expert domain knowledge to machines. Anesthesia is a complex medical specialty, and assuming AI can easily replace the expert as a clinically sound anesthetist is a very unrealistic expectation. This paper focuses on the association and opportunities for AI developments and deep learning with anesthesia. It reviews the current advances in AI tools and hardware technologies and outlines how these can be used in the field of anesthesia.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Trends for in-office usage of pharmacological sedation agents in India: A
           narrative review

    • Authors: Joshi; Sakshi; Gupta, Anil; Garg, Shalini; Dogra, Shikha
      Abstract: imageBackground and Aims: Conscious sedation plays a significant role in in-office pharmacological behavior management for short-term procedures in children and apprehensive adults. The advantage conscious sedation provides is by improving quality of care provided by decreasing pain and anxiety while maintaining a patent airway and adequate spontaneous ventilation.Methodology: Present review was conducted to evaluate recent trends regarding use of in-office pharmacological sedation agents in India. A rigorous search was conducted through five electronic databases namely PubMed, Scopus, Web of Science, Cochrane Database, and CTRI (Clinical Trial Registry – India). The search period was defined to be last 5 years, that is, from 1st January 2014 to 31st July 2019. Terminologies “Conscious Sedation,” “In-office Sedation,” “Midazolam,” “Nitrous Oxide,” “India” were included in the search. The Boolean Operation “OR” and “AND” were applied to combine the terminologies.Results: A total of 20 studies were identified following strict inclusion and exclusion criteria. The included studies were evaluated for study design, speciality involved, number of individuals and their age groups, drugs compared along with route and dosage, procedures undertaken, place of study and results. Dental fraternity (13) had more number of trials conducted as compared to medical fraternity (7) in the stimulated period, with South Indian region having maximum trials registered or published.Conclusion: Midazolam was observed to the drug of choice for in-office sedation procedures in Indian Scenario. The limitation of study is that the published clinical studies are limited to a few states of India.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Anesthesia for Per-oral endoscopic myotomy (POEM) – not so poetic!

    • Authors: Sarkar; Soumya; Khanna, Puneet; Gunjan, Deepak
      Abstract: imagePeroral endoscopic myotomy (POEM) is a promising natural orifice transluminal endoscopic procedure for the treatment of esophageal motility disorders, with similar effectiveness as of Heller myotomy. It is performed under general anesthesia in endoscopy suite. Creation of submucosal tunnel in the esophageal wall is a key component. The continuous insufflation of CO2 inadvertently tracks into surrounding tissues and leads to capno mediastinum, capno thorax, capno peritoneum, and subcutaneous emphysema. Thus, the challenges, for an anesthesiologist are not only providing remote location anesthesia, increased risk of aspiration during induction, but also early detection of these complications and specific emergency management. Though a therapeutic innovation, POEM remains an interdisciplinary challenge with no specific anesthesia care algorithms and evidence-based recommendations. The purpose of this review is to outline the anesthesia and periprocedural practices based on existing evidence.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • NK1 receptor antagonists versus other antiemetics in the prevention of
           postoperative nausea and vomiting following laparoscopic surgical
           procedures: a systematic review and meta-analysis

    • Authors: Cavaye; John; Dai, Bryan; Gurunathan, Karthik; Weir, Rachel M.; Yerkovich, Stephanie; Gurunathan, Usha
      Abstract: imageA systematic electronic search of MEDLINE, EMBASE, and CINAHL databases aimed at comparing neurokinin-1 receptor antagonists with other antiemetics in their prevention of postoperative nausea and vomiting in adult patients undergoing laparoscopic surgery identified seven randomized controlled trials for review and meta-analysis. Preoperative aprepitant 80 mg was found to reduce nausea (RR: 0.56, 95% CI: 0.41–0.75, I2 = 0%, P = 0.89) and vomiting (RR: 0.20, 95% CI: 0.05–0.77, I2 = 0%, P = 0.96) and resulted in complete response (RR: 1.61 (1.25-2.08), I2 = 0%, P = 0.70) within the first 2 hours following surgery as well as vomiting in 2–24 hours (RR: 0.09, 95% CI: 0.02-0.36, I2 = 0%; P = 0.81) when compared to placebo or no antiemetic therapy. Preoperative aprepitant 80 mg has a superior overall effect compared to placebo or other antiemetics in the first two hours postoperatively, and thereafter reduces the risk of vomiting alone in the first 24 hours following laparoscopic surgeries.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Anaesthesia for tracheal resection and anastomosis

    • Authors: Marwaha; Ashwin; Kumar, Akhil; Sharma, Shikha; Sood, Jayashree
      Abstract: imageTracheal resection anastomosis is one of the most challenging surgeries. Notable advances in this field have made possible a variety of surgical, anesthetic, and airway management options. There are reports of newer approaches ranging from use of supraglottic airway devices, regional anesthesia, and extracorporeal support. Endotracheal intubation with cross-field ventilation and jet ventilation are the standard techniques for airway management followed. These call for multidisciplinary preoperative planning and close communication during surgery and recovery. This review highlights the anesthetic challenges faced during tracheal resection and anastomosis with specific considerations to preoperative workup, classification of tracheal stenosis, airway management, ventilation strategies, and extubation. The newer advances proposed have been reviewed.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Anesthesia for tracheal resection and anastomosis: What is new!

    • Authors: Garg; Rakesh; Pandey, Khusboo
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Validity of P-POSSUM in adult cancer surgery (PACS)

    • Authors: Mukherjee; Sudipta; Kedia, Ankit; Goswami, Jyotsna; Chakraborty, Arunangshu
      Abstract: imageBackground and Aims: Objective prediction of postoperative morbidity and mortality can help clinicians for appropriate resource allocation and counseling of patients and their kin. Among different scoring systems, “Portsmouth- Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity” (P-POSSUM) includes both preoperative and intraoperative parameters for postoperative risk prediction. The aim of this study was to investigate the validity of morbidity prediction by P-POSSUM in patients requiring intensive care after undergoing major surgeries for gastrointestinal and gynecological malignancies.Material and Methods: All adult patients (>18 years) undergoing gastrointestinal and gynecological cancer surgeries who were shifted to intensive care unit (ICU) or high dependency unit (HDU) for postoperative care were included and P-POSSUM was measured. Postoperative complications were graded as per Clavien–Dindo (CD) grading and have been compared with predicted complications as per P-POSSUM.Results: 143 patients were included in the study and the median P-POSSUM score was 35. The mean predicted morbidity was 55.28% (SD 25.54%) and the observed complications were 45.45%, which shows P- POSSUM has over predicted morbidity. At P-POSSUM values 60 and above, the incidence of major complications was 22.22%, compared to 6.25% for the rest (Odds ratio 4.286).Conclusion: P-POSSUM is not a reliable predictor of postoperative morbidity for patients undergoing major gynecological and gastrointestinal surgeries for cancer in our institution. But there is a significant incidence of major complications with P- POSSUM morbidity prediction score 60 or higher leading to the need for more stringent assessment and monitoring in that subgroup.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • P-POSSUM for onco-surgeries: Does one suit fits all!

    • Authors: Garg; Rakesh; Rustagi, Kanika
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • A comparative study of sedo-analgesic effect of dexmedetomidine and
           dexmedetomidine with ketamine in postoperative mechanically ventilated

    • Authors: Gupta; Bikram K.; Mhaske, Vanita R.; Pai, Vishal Krishna; Mishra, L.D.
      Abstract: imageBackground and Aims: To compare the sedoanalgesic effects of dexmedetomidine alone or with combination of ketamine.Material and Methods: After getting ethical approval and informed patient consent, 60 adult surgical patients, were randomly divided into two groups. Group KD (n = 30); received dexmedotomidine 0.5 μg/kg/h mixed with ketamine 0.5 μg/kg/h and Group DEX (n = 30); received dexmedotomidine at 0.5 mg/kg/h infusion only. In both the groups, study drugs were titrated (dexmedetomidine- 0.2-0.7 μg/kg/h and ketamine 0.2-0.7 mg/kg/h) to achieve target sedation. Hemodynamic variables, pain scores, sedation scores, and patient satisfaction were recorded. Qualitative and Quantitative data were analyzed with Pearson Chi-squared test and analysis of variance test, respectively. All analyses were done by using statistical package for social sciences (SPSS) version 16.0.Results: Pain scores were higher in group DEX than in group KD at 2 h and 4 h which was statistically significant (P < 0.05). At the end of 2 h, sedation scores were higher in group KD than in group DEX and was statistically significant (P < 0.05). Length of intensive care unit stay was almost comparable in both groups, and the time to tracheal extubation was lesser in ketamine-dexmedetomidine group as compared to the dexmedetomidine alone group. However the difference was statistically non-significant.Conclusions: By combining dexmedetomidine with ketamine we observed lower incidence of hypotension and bradycardia. Dexmedetomidine with ketamine combination therapy could be used safely and effectively as sedo-analgesic agent.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Evaluation of a new laryngoscope blade (Manipal throat packing blade) for
           throat pack insertion

    • Authors: Muralikrishna; D; Nileshwar, Anitha; Budania, Lokvendra
      Abstract: imageBackground and aims: Insertion of a throat pack using a Macintosh laryngoscope after placing an oral Ring, Adair and Elwyn (RAE) tube fixed to the lower lip in the midline invariably results in the lateral movement of the tongue or the tube requiring repositioning. The aim was to design a laryngoscope blade that would produce minimal movement of the endotracheal tube or the tongue during the insertion of throat pack and compare it with the Macintosh laryngoscope blade.Material and Methods: A laryngoscope blade similar to the Doughty’s blade of Boyle Davis mouth gag with a groove in the center of the blade was initially designed. This was made of polyvinyl chloride to enable 3-D printing. Specifications given were modified after trial and error including addition of a flange. A bench study was then done to compare the Macintosh blade with the Manipal blade with and without flange. Forty anesthesia postgraduates and staff familiar with airway management inserted throat pack with each blade in random order in a manikin already intubated with an oral RAE tube and their impressions were noted.Results: The RAE tube remained in the midline after throat packing in 97.5 and 95% with Manipal blade with and without flange as compared to 52.5% with Macintosh blade. Ease of use was affected by the lack of sturdiness of the new blades. The light was good. Most people found both blades better or the same as the Macintosh blade.Conclusion: The Manipal laryngoscope blade with and without flange are both associated with the minimal lateral movement of the endotracheal tube and are easy to use. Their sturdiness must be improved.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparison of intrathecal bupivacaine-fentanyl and bupivacaine-butorphanol
           combinations for joint replacement surgeries

    • Authors: Sharma; Aakriti; Kumari, Anita; Gupta, Ruchi; Kaur, Shubhdeep; Arora, Deepika; Kaur, Keerat
      Abstract: imageBackground and Aims: The objective of the study was to compare duration of analgesia of fentanyl versus butorphanol as adjuvants to bupivacaine in spinal anesthesia.Material and Methods: A prospective, randomized, double-blinded study conducted in 80 patients of 18–75 years age group and American Society of Anesthesiologists Grades I and II undergoing joint replacement surgeries. A total of 40 patients in each Group A and Group B received 0.5% bupivacaine 3 ml with 25 mcg fentanyl and 25 mcg butorphanol respectively, in a total volume of 3.5 ml made with saline. Duration of analgesia, number of rescue analgesia, sensory, and motor block characteristics were compared between the two groups. Statistical analysis was done using t test and Chi-square test with SPSS 19.0 software.Results: Mean duration of analgesia was found more in Group B in comparison to Group A (P < 0.05). A number of doses of analgesic required postoperatively were more in Group A compared to Group B (P < 0.001). Time required for onset of sensory and motor block was comparable in both the groups. However, two segment regression of sensory block was slower in Group B compared to Group A (P < 0.05).Conclusion: We conclude that addition of butorphanol 25 μg as an adjuvant to 0.5% hyperbaric bupivacaine provided prolonged duration of analgesia compared to 25 mg fentanyl.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparison of two different volumes of 0.5%, ropivacaine used in
           ultrasound-guided adductor canal block after knee arthroplasty: A
           randomized, blinded, controlled noninferiority trial

    • Authors: Govil; Nishith; Tripathi, Mukesh; Goyal, Tarun; Bhardwaj, Bharat B.; Krishna, Vamshi; Choudhury, Arghya K.
      Abstract: imageBackground and Aims: The aim of this study was to establish noninferiority of 10 mL of 0.5% ropivacaine as compared to 20 mL of 0.5% ropivacaine; for choosing right dose in adductor canal block (ACB) after knee arthroplasty (KA), this trial was conducted.Material and Methods: Forty patients undergoing bilateral KA with postoperative ultrasound-aided ACB were randomized: Group A patients received 20 mL 0.5% ropivacaine in the right limb and 10 mL 0.5% ropivacaine in the left limb. Group B patients received 10 mL of 0.5% ropivacaine in the right limb and 20 mL of 0.5% ropivacaine in the left limb. Catheter is positioned for intermittent boluses every 12-h up to 48 h.Results: In the final analysis (excluding six patients) based on split-body design between Group I (comprising 34 limbs which received 20 mL of 0.5% ropivacaine) and Group II (comprising 34 limbs which received 10 mL of 0.5% ropivacaine), baseline demographic data were collected. Length of the limb from anterior superior iliac spine (ASIS) to the base of the patella was comparable between two groups: Group I (in cm; 149 ± 1.63) versus Group II (in cm; 149.5 ± 1.51) (P = 0.49, 95% CI of – 1.98 to 0.98). Primary outcomes, that is, quadriceps muscle strength, show a significant difference (P < 0.025) at various timeline. Secondary outcome pain scores and degree of knee flexion at various time intervals showed no significant difference. There was zero incidence of fall of the patient and no significant complication due to catheter was reported leading to discontinuation of catheter use in both groups.Conclusion: 10 mL of 0.5% ropivacaine is noninferior to 20 mL of 0.5% ropivacaine in providing postoperative analgesia with preserved quadriceps muscle strength.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparison of spinal anaesthesia with isobaric chloroprocaine and general
           anaesthesia for short duration ambulatory urological procedures

    • Authors: Ravi; Siddarth; Krishna, Handattu M.
      Abstract: imageBackground and Aims: Chloroprocaine is a short-acting local anaesthetic agent for spinal anaesthesia (SA) that has been used in day care surgeries due to its faster recovery characteristics and faster discharge rates compared to other local anaesthetics. This study aimed at finding out its efficacy for the same as compared to general anaesthesia (GA).Material and Methods: This observational study was conducted on 60 patients belonging to the American Society of Anaesthesiologists (ASA) physical status I and II who underwent short elective urological procedures (
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • El-Ganzouri multivariate risk index based airway management in head and
           neck cancer patients: A retrospective analysis of 1000 patients in a
           tertiary care center

    • Authors: Gupta; Raghav; Gupta, Nishkarsh; Kumar, Vinod; Garg, Rakesh; Bharati, Sachidanand J.; Mishra, Seema; Bhatnagar, Sushma
      Abstract: imageBackground and Aims: Intubation in head and neck carcinoma (HNC) is difficult due to many reasons. Various guidelines recommend strategies for airway management in such anticipated difficult airway cases. However, literature is limited on airway management planning as per the level of difficulty based on airway assessment in these patients. EL-Ganzouri risk index (EGRI) has been proposed to aid in making airway management plan in HNC cases by some authors. This retrospective study was conducted to look at the data related to the pre-anesthetic airway assessment and the airway management plan executed by the anesthesiologists in 1000 patients of HNC in the previous nearly four years in order to determine how the choices made conformed to EGRI scores.Material and Methods: Records of all the patients with oral cancer posted for surgery over four years from January 2014 to December 2017 were retrospectively analyzed for preoperative airway assessment using El Ganzouri risk index assessment (EGRI), the intraoperative technique for nasotracheal intubation, airway management plan, and any intraoperative complications.Results: The risk of predicted airway difficulty was low (EGRI 7 were intubated awake and those with EGRI
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparison of effect of etomidate with propofol on hemodynamics during
           modified electroconvulsive therapy

    • Authors: Mehta; Divya; Palta, Sanjeev; Gupta, Nitin; Saroa, Richa
      Abstract: imageBackground and Aims: Studies comparing the effect of propofol and etomidate on hemodynamic parameters during electroconvulsive therapy (ECT) have shown ambiguous results. Although some studies observed a larger increase in blood pressure and heart rate during the use of etomidate than propofol in ECT, whereas some studies have shown no difference in hemodynamic parameters with the use of etomidate or propofol. Most of the studies done to compare the hemodynamic effects of etomidate and propofol were limited by small sample size or retrospective in nature. Therefore, we conducted a prospective randomized trial to compare the effects of etomidate and propofol on hemodynamics during ECT.Material and Methods: A prospective randomized crossover study was conducted on 30 patients with American Society of Anesthesiologist physical status I and II, between age 18 and 65 years, suffering from a mental disorder as per International Classification of Diseases-10 and requiring bilateral ECT as per clinical decision of consultant psychiatrist. They were randomized to receive both the drugs for their successive ECT sessions and were subjected to evaluation after clubbing together the ECT sessions of propofol or etomidate as anesthetic agent.Results: Duration of motor seizures was significantly more in patients receiving etomidate, whereas patients receiving propofol had more stable hemodynamics.Conclusion: Though propofol maintains stable hemodynamics during MECT, yet clinical applicability of etomidate outstrips it by a reasonable margin due to its better effect on seizure parameters.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Patient satisfaction with anaesthesia services in a tertiary care cancer
           centre. (SAY study)

    • Authors: Ambulkar; Reshma; Patel, Alim; Patil, Sanika; Savarkar, Sukhada
      Abstract: imageBackground and Aims: Patient satisfaction is an important measure of quality of health care. Its assessment leads to a balanced evaluation of the structure, process and outcome of service at an institution. The aim of our study was to assess patient satisfaction with perioperative anaesthesia services provided in our institution and identify factors leading to dissatisfaction which could be preventable or addressed to improve patient care and experience.Material and Methods: A convenient sample size of 200 patients was accrued after written informed consent. A questionnaire to suit local needs of institute was developed, validated and a language appropriate questionnaire was administered by a trained research nurse 24–48 hours post anaesthesia to accrued patients. Data was summarised in percentages and satisfaction scores were compared across demographic variables using Chi square test.Results: A total of 96% (192/200) patients were satisfied with the overall interaction with the anaesthetists in the perioperative period; with 99% (198/200) patients being satisfied with acute pain services provided, postoperatively. As regards to recovery room, 96.5% (193/200) patients were satisfied with the services provided. Satisfaction scores of the pre-anaesthetic clinic (PAC), pain team and anaesthesia services compared across demographic variables – age, gender and education qualifications were found to be statistically non-significant.Conclusion: High rate of patients were satisfied with perioperative anaesthesia care services at our institute. Good and effective preoperative communication with the patient, effective management of postoperative pain and complications significantly contributed towards overall high patient satisfaction.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Risk factors for labor epidural conversion failure requiring general
           anesthesia for cesarean delivery

    • Authors: Grap; Shannon M.; Patel, Gaurav R.; Huang, Jessica; Vaida, Sonia J.
      Abstract: imageBackground and Aims: To evaluate the rate and risk factors of labor epidural conversion failure requiring general anesthesia for Caesarean delivery (CD).Material and Methods: Pregnant patients requiring conversion from labor to CD with a pre-existing labor epidural at our institution from 2009 to 2014 were identified. Through a retrospective review, we compared successful epidural conversion with those who required general anesthesia for CD. Patient characteristics were analyzed to identify risk factors for failed epidural conversion for CD.Results: A total of 673 patients were included in the study. The rate of epidural conversion failure was 21%. Main risk factors for epidural conversion failure requiring general anesthesia included: younger maternal age (95% CI 0.94, P = 0.0002) and supplementation of intravenous fentanyl (95% CI 0.19, P < 0.0001) or midazolam (95% CI 0.26, P = 0.0008) during CD. A higher risk of conversion failure was also associated with a more urgent CD (CD category 1, 2, and 3 vs category 4).Conclusion: Consistent with previous reports, young age and the urgency of CD increases the likelihood of epidural conversion failure. While conversion failure is likely multifactorial and complex, many of these factors are suggestive of inadequate and poorly functioning labor epidurals prior to CD. Prospective studies to further evaluate these factors are necessary, and the best prevention of epidural conversion failure is diligent diagnosis and evaluation of ineffective labor epidural analgesia prior to impending CD.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Role of endotracheal tube size on nasal and laryngeal morbidity during
           awake fiberoptic nasotracheal intubation: A Randomized controlled trial

    • Authors: Vinayagam; Stalin; Arikrishnan, Thirumurugan; Kundra, Pankaj; Saxena, Sunil Kumar
      Abstract: imageBackground and Aims: Awake fibreoptic nasotracheal intubation is associated with adverse airway and hemodynamic complications. The aim of this study was to evaluate the role of endotracheal tube size on nasal and laryngeal morbidity during awake fibreoptic-guided nasotracheal intubation.Material and Methods: Eighty patients recruited to undergo awake fibreoptic intubation were randomly allocated to Group C (standard size endotracheal tube) and Group S (small size endotracheal tube followed by exchange to standard size using Airway Exchange Catheter under general anesthesia). Nasal morbidity was assessed by incidence of epistaxis, olfactory acuity, and mucociliary clearance. Patient discomfort during intubation was assessed using grimace score and hemodynamic parameters were recorded. Postoperatively, the incidence of nasal and laryngeal injury was recorded using nasendoscopy and telelaryngoscopy, respectively.Results: Demographic profile between the two groups was comparable. Epistaxis was noted in 47.5% of patients in group C as compared to 12.5% in group S. Postoperative olfactory acuity was decreased [2 (1-4) vs 4 (2-5)] and saccharin clearance time was prolonged (314 s vs 134 s) in Group C as compared to Group S. (P-value
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparative evaluation of Intubating Laryngeal Mask Airway (ILMA), I-gel
           and Ambu AuraGain for blind tracheal intubation in adults

    • Authors: Sarma; Riniki; Kumar, Rakesh; Kumar, Neera Gupta; Agarwal, Munisha; Bhardwaj, Manoj; Ansari, Saud Ahmed; Deepak, G. P
      Abstract: imageBackground and Aims: The supraglottic airway devices (SADs) that allow direct (without an intermediary device like Aintree or airway exchange catheters) tracheal intubation can be invaluable for field use in conditions ideally managed by intubation. Whilst fiberscope-guided intubation is the method of choice, if these ‘direct-intubation’ SADs could provide high success rates for blind tracheal intubation, their scope of use can increase tremendously. Our study assesses intubating laryngeal mask airway (ILMA), i-gel and Ambu AuraGain for blind tracheal intubation in adults.Material and Methods: Ninety adults undergoing elective surgery were randomized into three equal groups. After induction of anesthesia, the group-specific SAD was inserted and on achieving adequate ventilation, blind tracheal intubation was attempted over two attempts. Success rates and time of achieving adequate device placement and tracheal intubation through these were evaluated. Data were analyzed using SPSS version 17.0 and P < 0.05 was considered statistically significant.Results: All three devices could achieve adequate ventilation within two allowed attempts. Successful tracheal intubation rates were significantly better with ILMA than i-gel on first attempt (87% vs. 27%, P < 0.001) and after second attempt that was supplemented with optimization maneuvers (100% vs. 40%, P < 0.001). No patient could be intubated through Ambu AuraGain within two attempts. Time taken for successful tracheal intubation did not differ significantly (P = 0.205) with ILMA or i-gel.Conclusion: Out of ILMA, I-gel and Ambu AuraGain, ILMA is the best device for blind tracheal intubation in adults with normal airways.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Comparison of the effect of propofol and isoflurane on hemodynamic
           parameters and stress response hormones during Laparoscopic
           Cholecystectomy surgery

    • Authors: Ghomeishi; Ali; Mohtadi, Ahmad Reza; Behaeen, Kaveh; Nesioonpour, Sholeh; Sheida Golbad, Elham; Bakhtiari, Nima
      Abstract: imageBackground and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses.Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient . The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery.Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level.Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P> 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05).Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Blind nasal intubation in a ‘breathing’ manikin- An idea

    • Authors: Kumar; Rakesh; Mathur, Aviral; Kumar, Sunil; Gupta, Nishkarsh; Kumar, Neera G.; Gupta, Ekta
      Abstract: imageBlind nasal intubation (BNI) has been around for over a century now. Many clinicians advocate it as an “old-is-gold” skill, which can be performed without any adjuncts in cases where visualization of larynx is a problem. Even today, BNI not only comes handy in resource-limited centers, it may also come to the rescue of airway managers in well-equipped centers. However, in the century since it was first described, there have been other major developments in the field of airway management and BNI as a skill has taken a backseat when it comes to a priority order. More so because it is limited by modalities to teach and train as most of the available manikins, which are otherwise phenomenal when it comes to imitating anatomy and overall attention to detail of a human airway, suffer terribly in one basic aspect needed to teach, train, and learn BNI—”they” cannot breathe! Attempts have been made to fabricate some manikins on these lines. But what if they can not only breathe but breathe out CO2 as well! We describe a simple method whereby we created a “CO2 breathing” manikin and tested it in an Airway Management Workshop with 105 participants, and then evaluated it under controlled conditions in 20 volunteers. We got very encouraging results and realized that our manikin makes the teaching and training of BNI very interesting and attractive by simulating the actual clinical scenario. We feel that it has the potential of reinventing the valuable skill of BNI.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • C Arm confirmation of lung isolation in pediatric patients undergoing
           video-assisted thoracoscopic decortication: A retrospective case series

    • Authors: Ponde; Vrushali; Patil, Anagha; Nagdev, Tripti; Gursale, Anuya
      Abstract: imageVideo-assisted thoracoscopic surgery (VATS) is a frequently performed procedure in children which requires an efficient technique for lung isolation. Unavailability of appropriate size double-lumen tubes (DLT) for children and fiber optic scopes inspired us to create our own technique for lung isolation. This retrospective case series aims to describe our technique of C arm-aided endotracheal tube (ETT) placement for one-lung ventilation in these patients. 15 patients, aged 3 months to 10 years posted for VATS were recruited. Standard monitoring, general anesthesia and Lung isolation done as per the described protocol. Mean, standard deviation, and 95% Confidence interval was used. The mean age and weight was 43.93 months was 16.4 kg respectively. All right bronchus intubations were achieved in the first attempt. Of the 8 left bronchus intubations, 4 needed more than one attempt with a stylet inserted with a gentle J-shaped curve. Mild desaturation, seen in 2 patients during surgery was corrected with neck extension and increasing the FiO2. None of the cases required withdrawal of the tube into the trachea. One-lung anesthesia was achieved successfully in all the cases using C Arm with routine ETT.
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Hypotension associated with high cardiac output and low systemic vascular
           resistance in a patient with hyperparathyroidism and hypercalcemia

    • Authors: Thangavel; Arun Raja; Vasudevan, Arumugam
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Perioperative anesthetic challenges in Alkaptonuria patient with comorbid

    • Authors: Ahuja; Vanita; Atter, Pradeep; Mundotiya, Sandhya; Garg, Sudhir
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • From precision of the evidence to the evidence for precision: An
           intriguing odyssey!

    • Authors: Magoon; Rohan; Makhija, Neeti; Jangid, Surendra K.; Das, Devishree
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Late venous air embolism following insertion of Mayfield head pins

    • Authors: Kapoor; Indu; Mahajan, Charu; Prabhakar, Hemanshu
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Loss of guide-wire during central venous cannulation – Life long

    • Authors: Deep; Gagan; Sidhu, Navdeep; Gupta, Kewal Krishan; Sharma, Raghuraj
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Anesthetic management of a case of chronic inflammatory demyelinating
           polyneuropathy undergoing major abdominal surgery

    • Authors: Batra; Ankita; Sahni, Neeru
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Transdermal opioids for acute postoperative pain: A road less travelled!

    • Authors: Gupta; Nishkarsh; Gupta, Anju
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • High Spinal Block: Type of Spinal Needle, Does it Matter'

    • Authors: Singh; Shalendra; Gupta, Nipun; Ambooken, George Cherian; Pradip, K. C.
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Erroneous measurement of hematocrit from arterial cannula on failed
           fistula limb site in renal transplant recipient: A cautious path to tread!

    • Authors: Garg; Heena; Gurajala, Indira; Durga, Padmaja
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Anesthetic management for large anterior mediastinal mass compressing
           great vessels of heart

    • Authors: Singh; Shalendra; Bhan, Sonia; Dwivedi, Deepak; Taank, Priya
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Does modulation of glymphatic system reduce delirium via waste

    • Authors: Naaz; Shagufta; Asghar, Adil
      Abstract: No abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Endotracheal intubation in an adult patient of Hallermann–Streiff
           syndrome—Case report and review of literature

    • Authors: Punj; Jyotsna; Singh, Anshul
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • “Look-alike” Guedel oropharyngeal airway

    • Authors: Vijayakumar; Vinodhadevi; Ganesamoorthi, Arimanickam
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
  • Prodigious Valve: Ultrasound Will Surely Help!!!

    • Authors: Mahajan; Shalvi; Garg, Shankey; Kumar, Sanjay; Chauhan, Rajeev
      Abstract: imageNo abstract available
      PubDate: Sat, 01 Jan 2022 00:00:00 GMT-
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