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- Issue Information
Abstract: Clinical and Translational Science, Volume 16, Issue 9, Page 1493-1496, September 2023.
PubDate: 2023-09-13T02:15:06-07:00
DOI: 10.1111/cts.13328
Issue No: Vol. 16, No. 9 (2023)
- Dose Selection for Biological Enzyme Replacement Therapy Indicated for
Inborn Errors of Metabolism
Authors:
Yuen Yi Hon; Jie Wang,
Henrietta Abodakpi,
Anand Balakrishnan,
Michael Pacanowski,
Sushanta Chakder,
Patroula Smpokou,
Kathleen Donohue,
Yow‐Ming C. Wang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-21T08:46:25-07:00
DOI: 10.1111/cts.13652
- The “One‐Step” approach for QT analysis increases the sensitivity of
nonclinical QTc analysis
Authors:
Derek J. Leishman; David L. Holdsworth,
D. Adam Lauver,
Marc B. Bailie,
Brian M. Roche
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-09-19T10:40:33-07:00
DOI: 10.1111/cts.13625
- Assessing Pharmacogenomic Literacy in China Through Validation of the
Chinese Version of the Minnesota Assessment of Pharmacogenomic Literacy
(MAPL‐C)
Authors:
Lusi Zhang; Shuqin Zhou,
Josiah D. Allen,
Fan Wang,
Amy L. Pittenger,
Jeffrey R. Bishop
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-18T04:15:07-07:00
DOI: 10.1111/cts.13637
- A Disease Model Predicting Placebo Response and Remission Status of
Patients with Ulcerative Colitis Using Modified Mayo Score
Authors:
Anita Moein; Jurgen Langenhorst,
Elodie L. Plan,
Jin Y. Jin,
Matts Kågedal,
Nastya Kassir
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-17T10:09:52-07:00
DOI: 10.1111/cts.13632
- Physiologically based absorption modeling to predict the bioequivalence of
two cilostazol formulations
Authors:
Lu Wang; Pengfei Zhao,
Ting Luo,
Dandan Yang,
Qianqian Jiang,
Jinliang Chen,
Honggang Lou,
Zourong Ruan,
Bo Jiang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-17T10:09:50-07:00
DOI: 10.1111/cts.13633
- Model‐informed precision dosing of vancomycin for rapid achievement of
target area under the concentration‐time curve: A simulation study
Authors:
Kazutaka Oda; Tomoyuki Yamada,
Kazuaki Matsumoto,
Yuki Hanai,
Takashi Ueda,
Masaru Samura,
Akari Shigemi,
Hirofumi Jono,
Hideyuki Saito,
Toshimi Kimura
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-17T09:44:42-07:00
DOI: 10.1111/cts.13626
- Prevalence and prescribing patterns of oral corticosteroids in the United
States, Taiwan and Denmark, 2009 – 2018
Authors:
Beth I. Wallace; Hui‐Ju Tsai,
Paul Lin,
Kristian Aasbjerg,
Ann Chen Wu,
Yi‐Fen Tsai,
Christian Torp‐Pedersen,
Akbar K. Waljee,
Tsung‐Chieh Yao
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-17T09:04:04-07:00
DOI: 10.1111/cts.13649
- Application of a physiologically based pharmacokinetic model to predict
isoniazid disposition during pregnancy
Authors:
Ogochukwu U. Amaeze; Nina Isoherranen
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-09-15T03:30:09-07:00
DOI: 10.1111/cts.13614
- Association between serum albumin to serum creatinine ratio and mortality
risk in patients with heart failure
Authors:
Shiyang Li; Xiaoshuang Xie,
Xiaobin Zeng,
Shihai Wang,
Jianjun Lan
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-14T09:48:02-07:00
DOI: 10.1111/cts.13636
- Effect of itraconazole and fluconazole on the pharmacokinetics of
valemetostat: An open‐label, phase I study in healthy subjects
Authors:
Masaya Tachibana; Shunji Matsuki,
Yutaro Maekawa,
Kana Kuroda,
Takako Shimizu,
Junko Tsutsumi,
Hitoshi Ishizuka
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-09-13T10:41:17-07:00
DOI: 10.1111/cts.13613
- Various effects of repeated rifampin dosing on coproporphyrin levels in
humans
Authors:
Jonny Kinzi; Markus Grube,
Karin Brecht,
Isabell Seibert,
Werner Siegmund,
Henriette E. Meyer zu Schwabedissen
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-13T09:59:32-07:00
DOI: 10.1111/cts.13629
- A Pilot Study to Identify Pharmacogenomic and Clinical Risk Factors
Associated with Opioid Related Falls and Adverse Effects in Older Adults
Authors:
Sophia Sheikh; Rosemarie Fernandez,
Carmen Smotherman,
Jennifer Brailsford,
Taimour Langaee,
Esteban Velasquez,
Morgan Henson,
Taylor Munson,
Andrew Bertrand,
Phyllis Hendry,
Stephen Anton,
Roger B. Fillingim,
Larisa H. Cavallari
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-13T09:53:16-07:00
DOI: 10.1111/cts.13634
- Reconsideration of the Current Models of Estimated Kidney Function‐based
Drug Dose Adjustment in Older Adults: The Role of Biological Age
Authors:
Radin Alikhani; Manjunath P. Pai
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-13T04:18:28-07:00
DOI: 10.1111/cts.13643
- Opportunities and Challenges of 5G Network Technology towards Precision
Medicine
Authors:
Chia Chao Kang; Tze Yan Lee,
Wai Feng Lim,
Wendy Wai Yeng Yeo
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-13T03:44:08-07:00
DOI: 10.1111/cts.13640
- Valproic acid treatment attenuates cisplatin‐induced kidney injury by
suppressing proximal tubular cell damage
Authors:
Toshihiko Yoshioka; Mitsuhiro Goda,
Masaya Kanda,
Sayuri Itobayashi,
Yugo Sugimoto,
Yuki Izawa‐Ishizawa,
Kenta Yagi,
Fuka Aizawa,
Koji Miyata,
Takahiro Niimura,
Hirofumi Hamano,
Takumi Sakurada,
Yoshito Zamami,
Keisuke Ishizawa
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-12T10:30:40-07:00
DOI: 10.1111/cts.13638
- Japan's COVID‐19 Treatment Strategy: An Examination of Approved Oral
Medications
Authors:
Yuka Higuchi; Yudai Kaneda,
Tetsuya Tanimoto
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-10T09:54:38-07:00
DOI: 10.1111/cts.13628
- Effects of triclabendazole and its metabolite exposure on the
heart‐rate–corrected QT intervals: A randomized, placebo‐ and
positive‐controlled thorough QT study in healthy individuals
Authors:
William T. Prince; Vinay Kumar Venishetty,
Jean Lecot,
Kasra Shakeri‐Nejad,
Cathy Gray,
Amanda Taylor,
Ganesh R. Iyer,
Julia Zack
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-09-08T11:12:15-07:00
DOI: 10.1111/cts.13564
- Pharmacokinetics, safety, and tolerability of inhaled remdesivir in
healthy participants
Authors:
Rita Humeniuk; Kavita Juneja,
Shuguang Chen,
Scott Ellis,
Olena Anoshchenko,
Deqing Xiao,
Aaron Share,
Matthew Johnston,
Santosh Davies,
Adam DeZure,
Joe Llewellyn,
Anu Osinusi,
Helen Winter,
Sandhya Girish,
Ramesh Palaparthy,
Mark Dresser
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-08T11:01:20-07:00
DOI: 10.1111/cts.13627
- Genomics and transcriptomic alterations of the glutamate receptors in
acute myeloid leukemia
Authors:
Amani Alqahtani; Mengxi Wang,
Mimi Lou,
Houda Alachkar
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-09-05T10:50:33-07:00
DOI: 10.1111/cts.13588
- Drug–drug interaction prediction of ziritaxestat using a physiologically
based enzyme and transporter pharmacokinetic network interaction model
Authors:
Jeremy Perrier; Virginie Gualano,
Eric Helmer,
Florence Namour,
Viera Lukacova,
Amit Taneja
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-09-04T10:35:02-07:00
DOI: 10.1111/cts.13622
- Pharmacokinetics, safety, and tolerability of BMS‐986263, a lipid
nanoparticle containing HSP47 siRNA, in participants with hepatic
impairment
Authors:
Hisham Qosa; Claudia H. M. C. Oliveira,
Giovanni Cizza,
Eric J. Lawitz,
Nicholas Colletti,
Jeffrey Wetherington,
Edgar D. Charles,
Giridhar S. Tirucherai
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-31T11:07:37-07:00
DOI: 10.1111/cts.13581
- Artificial intelligence in rare disease diagnosis and treatment
Authors:
Magda Wojtara; Emaan Rana,
Taibia Rahman,
Palak Khanna,
Heshwin Singh
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-30T06:13:34-07:00
DOI: 10.1111/cts.13619
- Treatment outcomes of secukinumab in adult patients with
moderate‐to‐severe plaque psoriasis in China: A real‐world
multicenter retrospective study
Authors:
Yangfeng Ding; Wei Li,
Xin Guan,
Na Liu,
Ying Zhou,
Gaojie Li,
Xiaohua Wang,
Zhidong Wang,
Xiao Xiao,
Bin Yang,
Chengzhi Lv,
Chunlei Zhang,
Yuling Shi
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-29T11:38:44-07:00
DOI: 10.1111/cts.13583
- CYP2C19 Genotypes and Osteoporotic Fractures in Long‐term Users of
Proton Pump Inhibitors: A Hospital‐based Study
Authors:
Yi‐Ju Liao; Yu‐Ting Chen,
Tzu‐Hung Hsiao,
Ching‐Heng Lin,
Ming‐Fen Wu,
Chiann‐Yi Hsu,
Yi‐Ming Chen,
Chun‐Sheng Hsu
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-28T11:22:06-07:00
DOI: 10.1111/cts.13620
- Co‐consuming green tea with raloxifene decreases raloxifene systemic
exposure in healthy adult participants
Authors:
John D. Clarke; Sabrina M. Judson,
Dan‐Dan Tian,
Trevor O. Kirby,
Rakshit S. Tanna,
Adrienn Matula‐Péntek,
Miklós Horváth,
Matthew E. Layton,
John R. White,
Nadja B. Cech,
Kenneth E. Thummel,
Jeannine S. McCune,
Danny D. Shen,
Mary F. Paine
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-28T09:25:49-07:00
DOI: 10.1111/cts.13578
- Feasibility study for a fully decentralized clinical trial in participants
with functional constipation symptoms
Authors:
Ki Young Huh; Woo Kyung Chung,
Jiyeon Park,
SeungHwan Lee,
Min‐Gul Kim,
Jaeseong Oh,
Kyung‐Sang Yu
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-25T11:14:05-07:00
DOI: 10.1111/cts.13617
- Gossypol improves myocardial dysfunction caused by sepsis by regulating
histone acetylation
Authors:
Xiaohui Shi; Xinwei Lv,
Dong Xiao
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-25T09:46:35-07:00
DOI: 10.1111/cts.13618
- Sarcopenia assessed by CT or MRI is associated with the loss of response
to biologic therapies in adult patients with Crohn's disease
Authors:
Jingjing Liu; Hongye Tang,
Tingting Lin,
Jiangchuan Wang,
Wenjing Cui,
Chao Xie,
Zhongqiu Wang,
Yugen Chen,
Xiao Chen
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-24T09:19:07-07:00
DOI: 10.1111/cts.13621
- A randomized, placebo‐controlled study to evaluate safety and
pharmacokinetics of ART‐001 with a novel oral pediatric formulation in
healthy subjects
Authors:
Akira Tanaka; Naoto Uemura,
Kanako Kuniyeda,
Haruhi Ando,
Toshinori Higashi,
Hiroshi Nagabukuro
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-22T02:59:19-07:00
DOI: 10.1111/cts.13597
- Deriving Protein Binding‐Corrected Chemical Concentrations for In
Vitro Testing
Authors:
Aditya R. Kolli
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-21T10:18:38-07:00
DOI: 10.1111/cts.13616
- Study protocol: a comparison of mobile and clinic‐based spirometry for
capturing the treatment effect in moderate asthma
Authors:
Elena S. Izmailova; Rachel Kilian,
Jessie P. Bakker,
Shawna Evans,
Anthony D. Scotina,
Theodore F. Reiss,
Dave Singh,
John A. Wagner
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-21T07:04:01-07:00
DOI: 10.1111/cts.13615
- Rethinking, Reducing, Refining the Classical Oral Tyramine Challenge Test
of MAO inhibitors
Authors:
Ewoud‐Jan Hoogdalem; Karen L. Smith,
Jan Hartstra,
John Constant
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-19T12:29:00-07:00
DOI: 10.1111/cts.13612
- A phase 1, randomized, ascending‐dose study to assess safety,
pharmacokinetics, and activity of GDC‐8264, a RIP1 inhibitor, in healthy
volunteers
Authors:
Nicholas S. Jones; Smita Kshirsagar,
Vishnu Mohanan,
Vidya Ramakrishnan,
Flavia Di Nucci,
Ling Ma,
Jialin Mao,
Hao Ding,
Sha Klabunde,
Domagoj Vucic,
Lin Pan,
Annemarie N. Lekkerkerker,
Yuan Chen,
Michael E. Rothenberg
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-19T12:24:42-07:00
DOI: 10.1111/cts.13607
- An innovative phase I study in healthy subjects to determine the mass
balance, elimination, metabolism, and absolute bioavailability of
mitapivat
Authors:
Chandra Prakash; Heidi Mangus,
Yan Yan,
Hua Yang,
Varsha Iyer
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-18T08:55:51-07:00
DOI: 10.1111/cts.13609
- A phase I, open‐label, single‐dose study to evaluate the effect of
hepatic impairment on the pharmacokinetics and safety of futibatinib
Authors:
Ling Gao; Ikuo Yamamiya,
Mark Pinti,
Juan Carlos Rondon,
Thomas Marbury,
Gareth Tomlinson,
Lukas Makris,
Nanae Hangai,
Volker Wacheck
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-08T09:45:10-07:00
DOI: 10.1111/cts.13585
- Clinical characteristics in early Parkinson's disease with excessive
daytime sleepiness: a cross‐sectional and longitudinal study
Authors:
Yumei Liu; Ling Xue,
Jun Zhao,
Kaixin Dou,
Guojun Wang,
Anmu Xie
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-08T04:15:25-07:00
DOI: 10.1111/cts.13610
- Pediatric Dosing for Locally Acting Drugs in Submissions to the US FDA
Between 2002‐2020
Authors:
Gelareh A. Abulwerdi; Anuradha Ramamoorthy,
Edward Bashaw,
Gilbert J. Burckart,
Rajanikanth Madabushi,
Elimika Pfuma Fletcher
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-08T04:10:48-07:00
DOI: 10.1111/cts.13611
- A randomised, controlled single and multiple ascending dose trial of the
safety, pharmacokinetics and pharmacodynamics of SN1011 in healthy
subjects
Authors:
Leilei Zhu; Rong Shi,
Tongfang Zhao,
Yujie Ye,
Jie Tang,
Yihui Hu,
Peng Peng,
Dong Wang,
Clement Chong,
Guolin Xu,
Shui‐on Leung,
Wei'an Yuan
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-08T03:50:47-07:00
DOI: 10.1111/cts.13606
- CYP2C19 loss‐of‐function alleles and use of omeprazole or esomeprazole
increase the risk of cardiovascular outcomes in patients using clopidogrel
Authors:
Markus Ramste; Markus Ritvos,
Sergei Häyrynen,
Johanna I. Kiiski,
Mikko Niemi,
Juha Sinisalo
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-08T03:50:41-07:00
DOI: 10.1111/cts.13608
- Intradermal substance P as a challenge agent in healthy individuals
Authors:
Wouter Voorde; Chika Akinseye,
Ismahaan Abdisalaam,
Selinde Wind,
Naomi Klarenbeek,
Menthe Bergmans,
Martijn Doorn,
Robert Rissmann,
Rejbinder Kaur,
Sarah Hotee,
Katie Foster,
Arati Nair,
Lea Fortunato,
Colin Macphee,
Sarah Mole,
Katrine Baumann,
Richard Brigandi
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-07T01:37:40-07:00
DOI: 10.1111/cts.13592
- Drug–Drug Interaction Study of Ciprofol and Sodium Divalproex:
Pharmacokinetics, Pharmacodynamics, and Safety in Healthy Chinese Subjects
Authors:
Dandan Yang; Wei Zhang,
Zourong Ruan,
Bo Jiang,
Siqi Huang,
Jiaying Wang,
Pengfei Zhao,
Mengyue Hu,
Min Yan,
Honggang Lou
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-03T11:24:46-07:00
DOI: 10.1111/cts.13605
- Keverprazan, a novel potassium‐competitive acid blocker: Multiple oral
doses safety, tolerability, pharmacokinetics, and pharmacodynamics in
healthy subjects
Authors:
Sufeng Zhou; Lijun Xie,
Chen Zhou,
Lu Wang,
Juan Chen,
Sijia Ding,
Bei Zhu,
Mei Su,
Feng Shao
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-02T09:40:17-07:00
DOI: 10.1111/cts.13598
- Areas of strength and opportunities for growth in translational science
education and training: Results of a scoping review from the NCATS
Education Branch
Authors:
Amanda L. Vogel; Brittany M. Haynes,
Shadab F. Hussain,
Lameese D. Akacem,
Marcus G. Hodges,
Josh A. Duberman,
Gisela Butera,
Jessica M. Faupel‐Badger
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-02T09:40:10-07:00
DOI: 10.1111/cts.13570
- Plasma lipidomic analysis to investigate putative biomarkers of
P‐glycoprotein activity in healthy volunteers
Authors:
Théodore Decaix; Romain Magny,
Isabelle Gouin‐Thibaut,
Xavier Delavenne,
Patrick Mismetti,
Joe‐Elie Salem,
Céline Narjoz,
Anne Blanchard,
Marion Pépin,
Nicolas Auzeil,
Marie‐Anne Loriot,
Olivier Laprévote
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-08-02T02:40:29-07:00
DOI: 10.1111/cts.13601
- Comparison of glutaminase and CA‐125 in distinguishing benign and
malignant ovarian tumors
Authors:
Gatot Nyarumenteng Adhipurnawan Winarno; Jusuf Sulaeman Effendi,
Ali Budi Harsono,
Siti Salima,
Bagja Dumas Darwizar,
R. M. Sonny Sasotya,
Anita Rachmawati,
Ayu Insafi Mulyantari,
Nurvita Trianasari,
Budi Handono
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-01T04:59:38-07:00
DOI: 10.1111/cts.13603
- Assessment of Pharmacokinetics, Safety, and Tolerability Following
Twice‐Daily Administration of Molnupiravir for 10 Days in Healthy
Participants
Authors:
Marian Iwamoto; Kelly E. Duncan,
Prachi K. Wickremasingha,
Tian Zhao,
Maria V. Liberti,
Lieselotte Lemoine,
Tatjana Decaesteker,
Sylvie Rottey,
Brian M. Maas,
Gillian Gillespie,
S. Aubrey Stoch
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-08-01T04:53:20-07:00
DOI: 10.1111/cts.13602
- Posaconazole and midostaurin in patients with FLT3‐mutated acute myeloid
leukemia: Pharmacokinetic interactions and clinical facts in a real life
study
Authors:
Pierantonio Menna; Francesco Marchesi,
Chiara Cattaneo,
Anna Candoni,
Mario Delia,
Gianpaolo Nadali,
Alessandra Vatteroni,
Crescenza Pasciolla,
Salvatore Perrone,
Luisa Verga,
Daniele Armiento,
Maria Ilaria Del Principe,
Nicola S. Fracchiolla,
Emanuela Salvatorelli,
Santina Lupisella,
Irene Terrenato,
Alessandro Busca,
Giorgio Minotti,
Livio Pagano
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-07-28T11:39:02-07:00
DOI: 10.1111/cts.13595
- TXNDC12 knockdown promotes ferroptosis by modulating SLC7A11 expression in
glioma
Authors:
Hao Yu; Kai Zhu,
Minjie Wang,
Xiaobing Jiang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-28T04:50:20-07:00
DOI: 10.1111/cts.13604
- Clinical covariates that improve the description of high dose methotrexate
pharmacokinetics in a diverse population to inform MTXPK.org
Authors:
Zachary L. Taylor; Tamara P. Miller,
Ethan A. Poweleit,
Nicholas P. DeGroote,
Lauren Pommert,
Oluwafunbi Awoniyi,
Sarah G. Board,
Ngozi Ugboh,
Vivek Joshi,
Nick Ambrosino,
Ashley Chavana,
Melanie B. Bernhardt,
Eric S. Schafer,
Maureen M. O'Brien,
Sharon M. Castellino,
Laura B. Ramsey
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-28T04:50:00-07:00
DOI: 10.1111/cts.13600
- Construction and evaluation of a risk prediction model for pulmonary
infection‐associated acute kidney injury in intensive care units
Authors:
Xinyi Cao; Yongzhi Liang,
Honglin Feng,
Li Chen,
Shengming Liu
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-24T09:33:51-07:00
DOI: 10.1111/cts.13599
- New score models for assessing disease activity in Crohn's disease based
on bowel ultrasound and biomarkers: Ideal surrogates for endoscopy or
imaging
Authors:
Qingyang Zhou; Qingli Zhu,
Wei Liu,
Wenbo Li,
Li Ma,
Mengsu Xiao,
Jingjuan Liu,
Hong Yang,
Jiaming Qian
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-07-21T11:39:35-07:00
DOI: 10.1111/cts.13575
- Investigation of the anticancer mechanism of monensin via
apoptosis‐related factors in SH‐SY5Y neuroblastoma cells
Authors:
Sema Serter Kocoglu; Ceren Oy,
Mücahit Secme,
F. Bahar Sunay
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-21T05:05:56-07:00
DOI: 10.1111/cts.13593
- Totality of Evidence of the effectiveness of repurposed therapies for
COVID‐19: Can we use Real‐World Studies alongside Randomised
Controlled Trials'
Authors:
Jaap Mandema; Hugh Montgomery,
Louis Dron,
Shuai Fu,
Estelle Russek‐Cohen,
Christina Bromley,
Samer Mouksassi,
Amy Lalonde,
Aaron Springford,
Larry Tsai,
Phil Ambery,
Doug McNair,
Nawab Qizilbash,
Stuart Pocock,
Névine Zariffa
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-19T05:19:42-07:00
DOI: 10.1111/cts.13591
- Prescription Patterns of P2Y12 Inhibitors Following Revascularization in
the United States: 2013‐2018
Authors:
Arun Kumar; Pamela L. Lutsey,
Wendy L. St. Peter,
Jon C. Schommer,
Jeremy R. Van't Hof,
Abhijeet Rajpurohit,
Joel F. Farley
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-19T05:18:03-07:00
DOI: 10.1111/cts.13596
- Exploration of smart adherence‐monitoring methods in vitamin
D‐deficient patients: A pilot, feasibility clinical study
Authors:
Ki Young Huh; Hwiwon Lee,
SeungHwan Lee,
Kyung‐Sang Yu,
Kyung Hwan Kim,
Heejin Kim
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-18T12:51:10-07:00
DOI: 10.1111/cts.13594
- Prevalence and utility of pharmacokinetic data in preclinical studies of
mRNA cancer vaccines
Authors:
Gillie A. Roth; Bianca Vora,
Chloe Kim,
Michael Wu,
Denison Kuruvilla
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-07-15T12:09:39-07:00
DOI: 10.1111/cts.13586
- Clinical Outcomes of Generic versus Brand‐name Clopidogrel for Secondary
Prevention in Patients with Acute Myocardial Infarction: A Nationwide
Cohort Study
Authors:
Cze Ci Chan; Ying‐Chang Tung,
Kuang‐Tso Lee,
Yi‐Hsin Chan,
Pao‐Hsien Chu
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-14T12:24:17-07:00
DOI: 10.1111/cts.13590
- Associations of HLA‐C*01:02 and HLA‐B*46:01 with regorafenib‐induced
erythema multiforme in Japanese patients with metastatic colorectal cancer
Authors:
Ken‐ichi Fujita; Natsumi Matsumoto,
Remi Murase,
Kosuke Takeshima,
Hiroo Ishida,
Yutaro Kubota
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-10T12:55:54-07:00
DOI: 10.1111/cts.13589
- Factors Explaining Individual Differences in the Oral Perception of
Capsaicin, l‐Menthol, and Aluminum Ammonium Sulfate
Authors:
Sulo Roukka; Sari Puputti,
Heikki Aisala,
Ulla Hoppu,
Laila Seppä,
Mari Sandell
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-10T12:54:55-07:00
DOI: 10.1111/cts.13587
- A decade comparison of regulatory decision patterns for oncology products
to all other non‐oncology products among Swissmedic, European Medicines
Agency, and US Food and Drug Administration
Authors:
Ulrich‐P. Rohr; Mario Iovino,
Leonie Rudofsky,
Qiyu Li,
Stephanie Juritz,
Arunas Gircys,
Oliver Wildner,
Magda Bujar,
Claus Bolte,
Simon Dalla Torre di Sanguinetto,
Anita Wolfer
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-07-05T09:44:12-07:00
DOI: 10.1111/cts.13567
- A phase I study comparing the pharmacokinetics and safety of HS628
(tocilizumab biosimilar) and reference tocilizumab in healthy male
subjects
Authors:
Hongjie Qian; Jie Cheng,
Yuzhou Gui,
Wei Wang,
Liyu Liang,
Huijuan Zhu,
Qingqing Wu,
Meixian Ou,
Qian Chen,
Chen Yu,
Jingying Jia
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-07-04T09:39:50-07:00
DOI: 10.1111/cts.13584
- Anti‐Inflammatory Effects of Dexamethasone in COVID‐19 Patients:
Translational Population PK/PD Modeling and Simulation
Authors:
Artur Świerczek; William J. Jusko
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-29T09:08:48-07:00
DOI: 10.1111/cts.13577
- Data Management 101 for Drug Developers: A Peek Behind the Curtain
Authors:
Bryan Oronsky; Erica Burbano,
Meaghan Stirn,
Joanne Brechlin,
Nacer Abrouk,
Scott Caroen,
Angelique Coyle,
Jeannie Williams,
Pedro Cabrales,
Tony R. Reid
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-29T04:40:53-07:00
DOI: 10.1111/cts.13582
- Variant‐Based Heritability Assessment of Dexmedetomidine and Fentanyl
Clearance in Pediatric Patients
Authors:
Morgan L. Shannon; Ayesha Muhammad,
Nathan T. James,
Michael L. Williams,
Joseph Breeyear,
Todd Edwards,
Jonathan D. Mosley,
Leena Choi,
Prince Kannankeril,
Sara Van Driest
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-23T08:58:31-07:00
DOI: 10.1111/cts.13574
- Longitudinal eGFR modeling in long‐term renal function to inform
clinical trial design in kidney transplantation
Authors:
Luke Kosinski; Eric Frey,
Amanda Klein,
Inish O’Doherty,
Klaus Romero,
Mark Stegall,
Ilkka Helanterä,
Osama Gaber,
William E. Fitzsimmons,
Varun Aggarwal,
Transplant Therapeutics Consortium (TTC)
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-23T01:05:14-07:00
DOI: 10.1111/cts.13579
- First‐in‐human phase 1 trial evaluating safety, pharmacokinetics, and
pharmacodynamics of NLRP3 inflammasome inhibitor, GDC‐2394, in
healthy volunteers
Authors:
Fei Tang; Rebecca Kunder,
Tom Chu,
Avis Hains,
Allen Nguyen,
Jacqueline M. McBride,
Yu Zhong,
Sara Santagostino,
Maria Wilson,
Abigail Trenchak,
Liuxi Chen,
Justin Ly,
Anita Moein,
Nicholas Lewin‐Koh,
Vibha Raghavan,
Uyi Osaghae,
Chris Wynne,
Ryan Owen,
David Place
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-23T01:04:18-07:00
DOI: 10.1111/cts.13576
- A Phase I Randomized, Double‐Blinded, Placebo‐Controlled Study
Assessing the Safety and Pharmacokinetics of RIPK1 Inhibitor GFH312 in
Healthy Subjects
Authors:
Jason Lickliter; Shuang Wang,
Wenxin Zhang,
Huaqiang Zhu,
Jing Wang,
Congqiao Zhao,
Haige Shen,
Yu Wang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-22T01:58:33-07:00
DOI: 10.1111/cts.13580
- Tacrolimus Pharmacokinetics are Influenced by CYP3A5, Age, and Concomitant
Fluconazole in Pediatric Kidney Transplant Patients
Authors:
Alaa Alghamdi; Sarah Seay,
David K. Hooper,
Charles Varnell,
Leanna Darland,
Tomoyuki Mizuno,
Danielle Lazear,
Laura B. Ramsey
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-20T11:08:44-07:00
DOI: 10.1111/cts.13571
- Abemaciclib does not increase the corrected QT interval in healthy
participants
Authors:
Jill C. Chappell; Alan Y. Chiang,
Jane Royalty,
Hugh Coleman,
Palaniappan Kulanthaivel,
P. Kellie Turner
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-19T11:21:58-07:00
DOI: 10.1111/cts.13573
- Remimazolam versus Propofol in Combination with Esketamine for Surgical
Abortion: A Double‐Blind Randomized Controlled Trial
Authors:
Linli Yue; Xiaoling Ma,
Na Li,
Jing Chen,
Jun Wang,
Zhenzhen Wan,
Lin Yang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-19T09:58:21-07:00
DOI: 10.1111/cts.13572
- Anticoagulant therapy in COVID‐19: A narrative review
Authors:
Zeinab Mohseni Afshar; Ali Tavakoli Pirzaman,
Rezvan Hosseinzadeh,
Arefeh Babazadeh,
Mohamad Ali Taghizadeh Moghadam,
Seyed Rouhollah Miri,
Terence T. Sio,
Mark J. M. Sullman,
Mohammad Barary,
Soheil Ebrahimpour
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-16T04:09:05-07:00
DOI: 10.1111/cts.13569
- Combined use of right ventricular coupling and pulmonary arterial
elastance as a comprehensive stratification approach for right ventricular
function
Authors:
Yihang Wu; Pengchao Tian,
Lin Liang,
Yuyi Chen,
Jiayu Feng,
Boping Huang,
Liyan Huang,
Xuemei Zhao,
Jing Wang,
Jingyuan Guan,
Xinqing Li,
Yuhui Zhang,
Jian Zhang
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-16T03:10:14-07:00
DOI: 10.1111/cts.13568
- Developing a Clinical Research Infrastructure embedded in an Academic
Medicine Center that Equitably Supports Future Clinician Scientists
Authors:
Maija Holsti; Heather T. Keenan,
Howard A. Kadish,
Heather K. Sapiro,
Angelo Giardino,
Katharine A. Osborn,
Kristen L. Cline,
Carrie L. Byington
Abstract: Clinical and Translational Science, Accepted Article.
PubDate: 2023-06-05T10:33:55-07:00
DOI: 10.1111/cts.13565
- Risk factors for the development of sepsis in patients with cirrhosis in
intensive care units
Authors:
Yan‐qi Kou; Yu‐ping Yang,
Shen‐shen Du,
Xiongxiu Liu,
Kun He,
Wei‐nan Yuan,
Biao Nie
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-05-29T12:10:30-07:00
DOI: 10.1111/cts.13549
- Assessment of the physical dependence potential of difelikefalin:
Randomized placebo‐controlled study in patients receiving hemodialysis
Authors:
Robert H. Spencer; Catherine Munera,
Megan J. Shram,
Frédérique Menzaghi
Abstract: Clinical and Translational Science, EarlyView.
PubDate: 2023-05-12T10:50:57-07:00
DOI: 10.1111/cts.13538
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