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- Benchmarking pharmacogenomics genotyping tools: Performance analysis on
short‐read sequencing samples and depth‐dependent evaluation
Authors:
Andreas Halman; Sebastian Lunke,
Simon Sadedin,
Claire Moore,
Rachel Conyers
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-09T08:53:20-07:00
DOI: 10.1111/cts.13911
Issue No: Vol. 17, No. 8 (2024)
- Using exploratory pharmacokinetic and pharmacodynamic analyses to predict
the probability of flu‐like symptoms in healthy volunteers and patients
with chronic hepatitis B treated with the toll‐like receptor 7 agonist
ruzotolimod
Authors:
Qiudi Jiang; Yuchen Zhang,
Dan Duan,
Sylvie Retout,
Ruchi Upmanyu,
Katerina Glavini,
Miriam Triyatni,
Yonghong Zhu,
Joseph F. Grippo,
Yuyan Jin
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-09T04:28:18-07:00
DOI: 10.1111/cts.13896
Issue No: Vol. 17, No. 8 (2024)
- Functional differences in the mu opioid receptor SNP 118A>G are dependent
on receptor splice‐variant and agonist‐specific recruitment of
β‐arrestin
Authors:
Casey Patrick; Utibeabasi Ettah,
Vu Nguyen,
Caitlin Hart,
Evan Atchley,
Krishna Mallela,
Robert I. Scheinman,
Andrew A. Monte
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-08T11:09:59-07:00
DOI: 10.1111/cts.13888
Issue No: Vol. 17, No. 8 (2024)
- Regulation of exosomes as biologic medicines: Regulatory challenges faced
in exosome development and manufacturing processes
Authors:
Chun‐Kai Wang; Teng‐Huang Tsai,
Chung‐Hsi Lee
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-08T05:20:00-07:00
DOI: 10.1111/cts.13904
Issue No: Vol. 17, No. 8 (2024)
- Exploring the discrepancies between clinical trials and real‐world data:
A small‐cell lung cancer study
Authors:
Luca Marzano; Adam S. Darwich,
Asaf Dan,
Salomon Tendler,
Rolf Lewensohn,
Luigi De Petris,
Jayanth Raghothama,
Sebastiaan Meijer
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-07T11:15:40-07:00
DOI: 10.1111/cts.13909
Issue No: Vol. 17, No. 8 (2024)
- Early administration of ketorolac after cardiac surgery and postoperative
complications: Analysis of the MIMIC‐IV database
Authors:
Yi Liu; Bo Pan,
Jie Liu,
Jun Zhang
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-05T04:35:18-07:00
DOI: 10.1111/cts.13907
Issue No: Vol. 17, No. 8 (2024)
- Real‐world evidence to support regulatory submissions: A landscape
review and assessment of use cases
Authors:
Golnoosh Alipour‐Haris; Xinyue Liu,
Virginia Acha,
Almut G. Winterstein,
Mehmet Burcu
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-02T05:48:35-07:00
DOI: 10.1111/cts.13903
Issue No: Vol. 17, No. 8 (2024)
- A case study of inclusion of rural populations in research: Implications
for science and health equity
Authors:
Devon Noonan; Wendy K. K. Lam,
James Goodrich,
Sydney Sullivan,
Keisha Bentley‐Edwards,
Dwight Koeberl,
Anushka Palipana,
F. Joseph McClernon
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-08-01T09:39:24-07:00
DOI: 10.1111/cts.13885
Issue No: Vol. 17, No. 8 (2024)
- Pharmacokinetics, pharmacodynamics, and safety of asundexian in healthy
Chinese and Japanese volunteers, and comparison with Caucasian data
Authors:
Huijun Chen; Kensei Hashizume,
Friederike Kanefendt,
Christine Brase,
Sebastian Schmitz,
Tianxing Liu
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-31T06:38:01-07:00
DOI: 10.1111/cts.13895
Issue No: Vol. 17, No. 8 (2024)
- Dupilumab: Mechanism of action, clinical, and translational science
Authors:
Marc R. McCann; Matthew P. Kosloski,
Christine Xu,
John D. Davis,
Mohamed A. Kamal
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-30T09:28:42-07:00
DOI: 10.1111/cts.13899
Issue No: Vol. 17, No. 8 (2024)
- Pharmacogenomics polygenic risk score: Ready or not for prime time'
Authors:
Sonal Singh; Gabriele Stocco,
Katherine N. Theken,
Alyson Dickson,
QiPing Feng,
Jason H. Karnes,
Jonathan D. Mosley,
Nihal El Rouby
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-30T06:35:07-07:00
DOI: 10.1111/cts.13893
Issue No: Vol. 17, No. 8 (2024)
- Drug–drug interactions between pemafibrate and statins on
pharmacokinetics in healthy male volunteers: Open‐label, randomized,
6‐sequence, 3‐period crossover studies
Authors:
Tomohiro Kamimura; Neil Hounslow,
Hideki Suganami,
Ryohei Tanigawa
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-30T05:59:02-07:00
DOI: 10.1111/cts.13900
Issue No: Vol. 17, No. 8 (2024)
- Pharmacokinetics and pharmacodynamics of itepekimab in adults with
moderate‐to‐severe atopic dermatitis: Results from two terminated
phase II trials
Authors:
Matthew P. Kosloski; Emma Guttman‐Yassky,
Michael J. Cork,
Margitta Worm,
Dong‐Ho Nahm,
Xiaoping Zhu,
Marcella K. Ruddy,
Sivan Harel,
Mohamed A. Kamal,
Hélène Goulaouic,
Christine R. Xu,
Elena Avetisova,
John D. Davis,
Michael C. Nivens,
Arsalan Shabbir,
Allen Radin
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-30T03:39:39-07:00
DOI: 10.1111/cts.13874
Issue No: Vol. 17, No. 8 (2024)
- Feasibility and accuracy of mobile QT interval monitoring strategies in
bedaquiline‐enhanced prophylactic leprosy treatment
Authors:
Auke T. Bergeman; Said Nourdine,
Alberto Piubello,
Zahara Salim,
Sofie M. Braet,
Abdallah Baco,
Silahi H. Grillone,
Rian Snijders,
Carolien Hoof,
Achilleas Tsoumanis,
Harry van Loen,
Younoussa Assoumani,
Aboubacar Mzembaba,
Nimer Ortuño‐Gutiérrez,
Epco Hasker,
Christian van der Werf,
Bouke C. de Jong
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-29T11:14:02-07:00
DOI: 10.1111/cts.13861
Issue No: Vol. 17, No. 8 (2024)
- Assessing the net financial benefits of employing digital endpoints in
clinical trials
Authors:
Joseph A. DiMasi; Abigail Dirks,
Zachary Smith,
Sarah Valentine,
Jennifer C. Goldsack,
Thomas Metcalfe,
Upinder Grewal,
Lada Leyens,
Ute Conradi,
Daniel Karlin,
Lesley Maloney,
Kenneth A. Getz,
Bert Hartog
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-28T09:54:59-07:00
DOI: 10.1111/cts.13902
Issue No: Vol. 17, No. 8 (2024)
- Translational pharmacokinetic/pharmacodynamic model for mRNA‐0184, an
investigational therapeutic for the treatment of heart failure
Authors:
Neeraj Kaushal; Husain Attarwala,
Mir Javid Iqbal,
Rajnish Saini,
Linh Van,
Min Liang
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-27T12:39:26-07:00
DOI: 10.1111/cts.13894
Issue No: Vol. 17, No. 8 (2024)
- Issue Information
Abstract: Clinical and Translational Science, Volume 17, Issue 8, August 2024.
PubDate: 2024-07-26T04:28:30-07:00
DOI: 10.1111/cts.13339
Issue No: Vol. 17, No. 8 (2024)
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