JournalTOCs

Expert Opinion on Investigational Drugs
Journal Prestige (SJR): 1.166

Citation Impact (citeScore): 3
Number of Followers: 10

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1354-3784 - ISSN (Online) 1744-7658
Published by Taylor and Francis

[2652 journals]

A four-in-one first-in-human study to assess safety, tolerability,
pharmacokinetics, pharmacodynamics, and concentration-QTc relationship of
HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist,
in healthy men
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  Authors: Qi Shen Lingzhi Li Weilin Qian Xue Dong Manchen Bao Rong Huang Na Li Zi Ye Gang Cheng Quanren Wang Kai Shen Zhu Luo a Department of Pharmacy; NMPA Key Laboratory for Clinical Research Development, Jiangsu Hengrui Pharmaceuticals, Shanghai, China
  Pages: 1 - 11
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-27T05:24:07Z
  DOI: 10.1080/13543784.2024.2393867
Application of engineered antibodies (scFvs and nanobodies) targeting
pathological protein aggregates in Alzheimer’s disease
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  Authors: Yuan Zhang Wanpeng Yu Lei Zhang Peifeng Li a Institute for Translational Medicine; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Chinab Medical Collage, Qingdao University, Qingdao, China
  Pages: 1 - 16
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-26T12:55:28Z
  DOI: 10.1080/13543784.2024.2396911
The first-in-human study to assess the safety, tolerability,
pharmacokinetics, and pharmacodynamics of the factor XI monoclonal
antibody SHR-2004 in healthy subjects
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  Authors: Tingting Ma Zuyi Weng Bei Cao Yanli Dong Chanjuan Deng Lei Huang Yuanxun Yang Yuqi Wang Chenxi Shen Lei Wang Kai Shen Juan Li a Phase I Clinical Trials Unit, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Chinab Clinical Research & Development, Jiangsu Hengrui Pharmaceuticals Co; Ltd, Shanghai, Chinac Protein biology department, Beijing TUO JIE Biopharmaceutical Co. Ltd, Beijing, China
  Pages: 1 - 8
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-23T04:32:00Z
  DOI: 10.1080/13543784.2024.2391837
Pharmacokinetics, pharmacodynamics, safety, and tolerability of a
single-dose riliprubart, an anti-C1s humanized monoclonal antibody in
East-Asian adults: results from a Phase 1, randomized, open-label trial
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  Authors: Yingxin Li Joo Young Na Yunting Zhu Jaeseong Oh Amy Zhao In-Jin Jang Lei Tang a Translational Medicine; Early Development, Sanofi, Suzhou, China
  Pages: 1 - 12
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-23T04:23:51Z
  DOI: 10.1080/13543784.2024.2394186
Recent progress in tyrosine kinase 2 inhibitors for atopic dermatitis
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  Authors: Qi Liu Yuan Xia Lin Liu Yuan Zhou Yumei Li a Department of Dermatology; Affiliated Hospital of Jiangsu University, Zhenjiang, Chinab Laboratory for Regeneration Medicine, Jiangsu University, Zhenjiang, China
  Pages: 1 - 7
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-22T05:24:37Z
  DOI: 10.1080/13543784.2024.2391825
Olaparib monotherapy or in combination with abiraterone for treating
mutated metastatic castration-resistant prostate cancer: alone or stronger
together'
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  Authors: Sarah E. Fenton Maha Hussain a Department of Medicine; Division of Hematology/Oncology, Northwestern University, Chicago, IL, USAb Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
  Pages: 1 - 7
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-20T12:46:46Z
  DOI: 10.1080/13543784.2024.2391828
Spleen tyrosine kinase (SYK): an emerging target for the assemblage of
small molecule antitumor agents
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  Authors: Charanjit Kaur Amandeep Thakur Ke-Chi Liou Neralla Vijayakameswara Rao Kunal Nepali a School of Pharmaceutical Sciences; Lovely Professional University, Phagwara, Indiab School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwanc Department of Chemical Engineering, National Taiwan University of Science Technology, Taipei, Taiwan
  Pages: 1 - 18
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-12T06:08:48Z
  DOI: 10.1080/13543784.2024.2388559
Factor IX stimulants in preclinical and early phase trials for hemophilia
B treatment
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  Authors: Massimo Franchini Daniele Focosi a Department of Transfusion Medicine; Hematology, Carlo Poma Hospital, Mantua, Italyb North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy
  Pages: 1 - 6
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-12T05:48:49Z
  DOI: 10.1080/13543784.2024.2388565
An overview of conventional and investigational phosphodiesterase 5
inhibitors for treating erectile dysfunction and other conditions
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  Authors: Ezzat A. Ismail Ahmed I. El-Sakka Department of Urology; Suez Canal University, Ismailia, Egypt
  Pages: 1 - 14
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-12T05:36:44Z
  DOI: 10.1080/13543784.2024.2388569
Investigational CXCR4 inhibitors in early phase development for the
treatment of hematological malignancies
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  Authors: Enrica Antonia Martino Antonella Bruzzese Caterina Labanca Francesco Mendicino Eugenio Lucia Virginia Olivito Gaia Stanzione Annamaria Zimbo Stefano Pozzi Antonino Neri Fortunato Morabito Ernesto Vigna Massimo Gentile a Hematology Unit; Azienda Ospedaliera Annunziata, Cosenza, Italyb Division of Hematology, Azienda Policlinico-S. Marco, University of Catania, Catania, Italyc UOC Laboratorio Analisi Cliniche, Biomolecolari e Genetica, Azienda Ospedaliera Annunziata, Cosenza, Italyd Ematologia Azienda USL-IRCSS Reggio Emilia, Reggio Emilia, Emilia-Romagna, Italye Scientific Directorate IRCCS of Reggio Emilia, Reggio Emilia, EmiliaRomagna, Italyf Biotechnology Research Unit, AO of Cosenza, Cosenza, Italyg Department of Pharmacy, Health Nutritional Science, University of Calabria, Rende, Italy
  Pages: 1 - 10
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-09T04:23:19Z
  DOI: 10.1080/13543784.2024.2388567
Investigative agents for atrial fibrillation: agonists and stimulants,
progress and expectations
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  Authors: Ruben Casado-Arroyo Marco Bernardi Pierre Sabouret Giuseppe Franculli Juan Tamargo Luigi Spadafora Nicolas Lellouche Giuseppe Biondi-Zoccai Peter P. Toth Maciej Banach a Department of Cardiology; H.U.B.-Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgiumb Department of Clinical, Internal Medicine, Anesthesiology Congenital Diseases of Adults, Polish Mother’s Memorial Hospital Research Institute Lodz Poland, Lodz, Poland
  Pages: 1 - 12
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-08T12:57:47Z
  DOI: 10.1080/13543784.2024.2388583
Investigational new drug approval of DA-1241: what we know about GPR119
targeting for MASH therapy'
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  Authors: Khaled Al Smadi Ammar Qureshi Besher Ashouri Zeid Kayali Department of Gastroenterology; Hepatology, University of California - Riverside School of Medicine, Rialto, CA, USA
  Pages: 1 - 4
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-07T07:16:59Z
  DOI: 10.1080/13543784.2024.2388592
Early psoriatic arthritis: clinical and therapeutic challenges
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  Authors: Francesco Caso Luisa Costa Matteo Megna Mario Cascone Francesco Maione Roberto Giacomelli Raffaele Scarpa Piero Ruscitti a Department of Clinical Medicine; Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  Pages: 1 - 21
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-07T02:03:54Z
  DOI: 10.1080/13543784.2024.2383421
Zanzalintinib (XL092): a next-generation tyrosine kinase
inhibitor—comprehensive review of early safety & efficacy data
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  Authors: James Yu Robin Park Alireza Tojjari Arezoo Sadeghipour Ali Saeed Anwaar Saeed a Division of Hematology; Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAc Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modarres University, Tehran, Irand Department of Medicine, Ochsner Lafayette General Medical Center, Lafayette, LA, USA
  Pages: 1 - 9
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-08-07T02:01:53Z
  DOI: 10.1080/13543784.2024.2388571
Developing targeted therapeutics for hepatocellular carcinoma: a critical
assessment of promising phase II agents
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  Authors: Elisabeth Amadeo Silvia Foti Silvia Camera Federico Rossari Mara Persano Federica Lo Prinzi Francesco Vitiello Andrea Casadei-Gardini Margherita Rimini a Department of Oncology; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italyb San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute Hospital, Milan, Italyc Medical Oncology, University University Hospital of Cagliari, Cagliari, Italyd Operative Research Unit of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy
  Pages: 1 - 11
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-23T04:27:48Z
  DOI: 10.1080/13543784.2024.2377321
Investigational and emerging gastric inhibitory polypeptide (GIP)
receptor-based therapies for the treatment of obesity
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  Authors: Robert H. Gaffey Afua K. Takyi Alpana Shukla Comprehensive Weight Control Center; Division of Endocrinology, Diabetes, Metabolism, Department of Medicine, Weill Cornell Medicine, New York, NY, USA
  Pages: 1 - 17
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-17T11:43:03Z
  DOI: 10.1080/13543784.2024.2377319
Safety, tolerability and pharmacokinetics of ASC10, a novel oral double
prodrug of a broad-spectrum antiviral agent, β-d-N4-hydroxycytidine:
results from a randomized, double-blind, placebo-controlled phase 1 study
in Chinese healthy subjects
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  Authors: Jian Liu Qingwei Zhao You Zhai Xia Wu Jiejing Kai Jie Ruan Minglan Wu Meijia Wu Zhuojun Zhou Yuemei Yan Jinzi J. Wu Yunqing Qiu a Research Center for Clinical Pharmacy; Department of Clinical Pharmacy, Zhejiang Provincial Key Laboratory for Drug Evaluation Treatment of Infectious Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
  Pages: 1 - 10
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-12T08:58:43Z
  DOI: 10.1080/13543784.2024.2377318
Medical treatments for abdominal aortic aneurysm: an overview of clinical
trials
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  Authors: Jinyi Chen Lanting Hu Zhenjie Liu Department of Vascular Surgery; The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
  Pages: 1 - 14
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-11T12:19:27Z
  DOI: 10.1080/13543784.2024.2377747
Emerging treatment landscape for Guillain-Barré Syndrome (GBS):
what’s new'
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  Authors: Alina Sprenger-Svačina Martin K.R. Svačina Tong Gao Gang Zhang Kazim A. Sheikh a Department of Neurology; University of Texas Health Science Center at Houston, Houston, TX, USAb Department of Neurology, Faculty of Medicine University Hospital of Cologne, University of Cologne, Cologne, Germany
  Pages: 1 - 6
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-10T11:31:45Z
  DOI: 10.1080/13543784.2024.2377323
New investigational drugs for steroid-refractory acute graft-versus-host
disease: a review of the literature
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  Authors: Na Hyun Kim Mehdi Hamadani Sameem Abedin Division of Hematology; Oncology, Department of Medicine, Medical College of Wisconsin Cancer Center, Milwaukee, WI, USA
  Pages: 1 - 9
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-10T05:46:57Z
  DOI: 10.1080/13543784.2024.2377322
Monoclonal antibodies targeting interleukins for systemic lupus
erythematosus: updates in early clinical drug development
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  Authors: Claudio Cruciani Mariele Gatto Luca Iaccarino Andrea Doria Margherita Zen a Rheumatology Unit; Department of Medicine, University of Padua, Padova, Italyb Rheumatology Unit, Department of Clinical Turin Mauriziano Hospital, Turin, Italy
  Pages: 1 - 14
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-10T05:38:59Z
  DOI: 10.1080/13543784.2024.2376566
Trastuzumab-deruxtecan in solid tumors with HER2 alterations: from early
phase development to the first agnostic approval of an antibody–drug
conjugate
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  Authors: Crimini Edoardo Curigliano Giuseppe a Department of Oncology; Hemato-Oncology, University of Milan, Milan, Italyb Division of Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, Milan, Italyc Department of Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA
  Pages: 1 - 15
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-09T01:02:17Z
  DOI: 10.1080/13543784.2024.2376573
An overview of the safety and efficacy of LX-9211 in treating neuropathic
pain conditions
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  Authors: William C. Upshaw John M. Richey Gurjot Ravi Adrian Chen Shahab Ahmadzadeh Sahar Shekoohi Omar Viswanath Alan D. Kaye a School of Medicine; Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USAb School of Medicine, Ross University School of Medicine, Miramar, FL, USAc Department of Anesthesiology, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, USAd Valley Pain Consultants, Envision Physician Services, Phoenix, AZ, USAe Department of Anesthesiology, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USAf Department of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USAg Departments of Anesthesiology Neurosciences, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, USA
  Pages: 1 - 9
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-08T08:33:28Z
  DOI: 10.1080/13543784.2024.2376570
Rheumatoid arthritis extra-articular lung disease: new insights on
pathogenesis and experimental drugs
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  Authors: Marco Sebastiani Andreina Manfredi Stefania Croci Paola Faverio Giulia Cassone Caterina Vacchi Carlo Salvarani Fabrizio Luppi a Department of Medicine; Reggio Emilia, Modena, Italy
  Pages: 1 - 13
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-07-05T01:32:49Z
  DOI: 10.1080/13543784.2024.2376567
VERVE-101, a CRISPR base-editing therapy designed to permanently
inactivate hepatic PCSK9 and reduce LDL-cholesterol
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  Authors: Amanda J. Hooper Xuan L. Tang John R. Burnett a Department of Clinical Biochemistry; PathWest Laboratory Medicine WA, Royal Perth Hospital & Fiona Stanley Hospital Network, Perth, Western Australia, Australiab School of Medicine, University of Western Australia, Perth, Western Australia, Australia
  Pages: 1 - 4
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-06-21T02:09:28Z
  DOI: 10.1080/13543784.2024.2369747
Secondary hyperparathyroidism in chronic kidney disease: pathophysiology,
current treatments and investigational drugs
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  Authors: Lorenza Magagnoli Paola Ciceri Mario Cozzolino a Department of Health Sciences; University of Milan, IT, Milano, Italyb Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, IT, Milano, Italy
  Pages: 1 - 15
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-06-19T12:50:31Z
  DOI: 10.1080/13543784.2024.2369307
Targeting diarrhea-predominant irritable bowel syndrome: hopes or
hypes'
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  Authors: Gabrio Bassottia Gastroenterology & Hepatology Section; Department of Medicine Surgery, University of Perugia, Perugia, Italyb Gastroenterology Unit, Perugia General Hospital, Perugia, Italy
  Pages: 1 - 4
  Abstract: .
  
  Citation: Expert Opinion on Investigational Drugs
  PubDate: 2024-04-25T02:16:27Z
  DOI: 10.1080/13543784.2024.2347296

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