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- Pharmacokinetics, safety, and tolerability of TQC3564, a novel CRTh2
receptor antagonist: report of the first-in-human single- and multiple-dose escalation trials in healthy Chinese subjects-
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Authors: Xiaojiao Li, Qianqian Li, Tianliang Ji, Hong Zhang, Jingrui Liu, Min Wu, Hong Chen, Jinfeng Lou, Chengjiao Liu, Zhongnan Xu, Yanhua Ding Pages: 1 - 8 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-18T07:19:29Z DOI: 10.1080/13543784.2022.2078192
- Adenosine pathway inhibitors: novel investigational agents for the
treatment of metastatic breast cancer-
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Authors: Alessandro Rizzo, Raffaella Massafra, Annarita Fanizzi, Lucia Rinaldi, Antonio Cusmai, Agnese Latorre, Gian Maria Zaccaria, Maria Ronchi, Michele Telegrafo, Gennaro Gadaleta-Caldarola, Francesco Giotta, Vito Lorusso, Gennaro Palmiotti Pages: 1 - 7 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-18T07:19:09Z DOI: 10.1080/13543784.2022.2078191
- Investigational drugs for ischemic stroke: what’s in the clinical
development pipeline for acute phase and prevention'-
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Authors: Maria Giulia Mosconi, Maurizio Paciaroni, Walter Ageno Pages: 1 - 23 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-13T07:15:39Z DOI: 10.1080/13543784.2022.2072725
- Investigational drugs for immune thrombocytopenia
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Authors: Drew Provan, Adrian C Newland Pages: 1 - 13 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-11T07:19:46Z DOI: 10.1080/13543784.2022.2075340
- Novel immunotherapy combinations in clinical trials for hepatocellular
carcinoma: will they shape the future treatment landscape' Open Access Article-
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Authors: Claudia Angela Maria Fulgenzi, Antonio D’Alessio, Olabisi Ogunbiyi, Coskun O. Demirtas, Alessandra Gennari, Alessio Cortellini, Rohini Sharma, David James Pinato Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-06T12:06:51Z DOI: 10.1080/13543784.2022.2072726
- PARP inhibitors as single agents and in combination therapy: the most
promising treatment strategies in clinical trials for BRCA-mutant ovarian and triple-negative breast cancers-
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Authors: Linjie Luo, Khandan Keyomarsi Pages: 1 - 25 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-03T03:14:33Z DOI: 10.1080/13543784.2022.2067527
- Clinical development of antibody-drug conjugates in triple negative breast
cancer: can we jump higher'-
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Authors: Dimitrios Zardavas Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-05-02T03:48:59Z DOI: 10.1080/13543784.2022.2070064
- Heart failure with preserved ejection fraction: key stumbling blocks for
experimental drugs in clinical trials-
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Authors: Amanda Lloji, Jayakumar Sreenivasan, Joel Novograd, Wilbert S. Aronow, Stephen Pan, Gregg M. Lanier Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-04-27T11:38:17Z DOI: 10.1080/13543784.2022.2069009
- A randomized, open-label, single-dose, two-cycle crossover study to
evaluate the bioequivalence and safety of lenvatinib and Lenvima® in Chinese healthy subjects-
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Authors: Zhongnan Xu, Yanli Wang, Guangwen Liu, Jiahui Chen, Wanhua Wang, Yang Cheng, Qing Ren, Yingzi Cui, Wei Yang, Zhengzhi Liu, Xuesong Chen, Jinling Xue, Tianying Chang, Xinyao Qu, Shuang Yu, Yannan Zhou, Kaibo Xu, Zhengjie Su, Qiaohuan Deng, Yicheng Zhao, Haimiao Yang Pages: 1 - 10 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-04-19T11:19:30Z DOI: 10.1080/13543784.2022.2067528
- Risdiplam: an investigational survival motor neuron 2 (SMN2) splicing
modifier for spinal muscular atrophy (SMA) Open Access Article-
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Authors: Theodora Markati, Gemma Fisher, Sithara Ramdas, Laurent Servais Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-04-11T01:08:17Z DOI: 10.1080/13543784.2022.2056836
- CAR-T cell therapy for triple-negative breast cancer and other solid
tumors: preclinical and clinical progress-
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Authors: Chiara Corti, Konstantinos Venetis, Elham Sajjadi, Lorenzo Zattoni, Giuseppe Curigliano, Nicola Fusco Pages: 1 - 13 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-24T08:38:36Z DOI: 10.1080/13543784.2022.2054326
- Repurposing tetracyclines for acute respiratory distress syndrome (ARDS)
and severe COVID-19: a critical discussion of recent publications-
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Authors: Jose Garrido-Mesa, Kate Adams, Julio Galvez, Natividad Garrido-Mesa Pages: 1 - 8 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-23T08:29:43Z DOI: 10.1080/13543784.2022.2054325
- Tucatinib: an investigational novel therapeutic agent for the treatment of
HER-2 colorectal cancer-
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Authors: Daniel Ahn, Daniel Walden, Tanios Bekaii-Saab Pages: 1 - 5 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-17T09:31:57Z DOI: 10.1080/13543784.2022.2053107
- KSI-301: an investigational anti-VEGF biopolymer conjugate for retinal
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Authors: Hudson D. Stern, Rehan M Hussain Pages: 1 - 7 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-16T07:50:31Z DOI: 10.1080/13543784.2022.2052042
- Why does survival of hepatocellular carcinoma patients remain so low'
Key stumbling blocks and questions in preclinical and clinical development -
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Authors: Margherita Rimini, Nicole Liscia, Valentina Burgio, Andrea Casadei-Gardini Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-16T05:17:05Z DOI: 10.1080/13543784.2022.2053108
- Progress and pitfalls in the use of immunotherapy for patients with triple
negative breast cancer-
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Authors: Elisa Agostinetto, Agnese Losurdo, Guilherme Nader-Marta, Armando Santoro, Kevin Punie, Romualdo Barroso, Lazar Popovic, Cinzia Solinas, Marleen Kok, Evandro de Azambuja, Matteo Lambertini Pages: 1 - 25 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-03-09T04:10:28Z DOI: 10.1080/13543784.2022.2049232
- Ladiratuzumab vedotin for metastatic triple negative cancer: preliminary
results, key challenges, and clinical potential-
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Authors: Alessandro Rizzo, Antonio Cusmai, Silvana Acquafredda, Lucia Rinaldi, Gennaro Palmiotti Pages: 1 - 4 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-02-18T02:10:18Z DOI: 10.1080/13543784.2022.2042252
- A randomized, adaptive design, double-blind, 3-arm, parallel study
assessing the pharmacokinetics and safety of AVT02, a high-concentration (100 mg/mL) Adalimumab biosimilar, in healthy adult subjects (ALVOPAD FIRST) Open Access Article-
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Authors: Christopher Wynne, Christian Schwabe, Charlotte Lemech, Heimo Stroissnig, Roshan Dias, Joanna Sobierska, Eric Guenzi, Hendrik Otto, Abid Sattar, Richard Kay, Halimu N. Haliduola, Fausto Berti Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2022-02-10T02:25:59Z DOI: 10.1080/13543784.2022.2035359
- Immune-based combinations for metastatic triple negative breast cancer in
clinical trials: current knowledge and therapeutic prospects-
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Authors: Alessandro Rizzo, Angela Dalia Ricci, Laura Lanotte, Lucia Lombardi, Alessandro Di Federico, Giovanni Brandi, Gennaro Gadaleta-Caldarola Pages: 1 - 9 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-12-14T06:51:51Z DOI: 10.1080/13543784.2022.2009456
- Biomarkers for breast cancer immunotherapy: PD-L1, TILs, and beyond
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Authors: Alessandro Rizzo, Angela Dalia Ricci Pages: 1 - 7 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-11-25T02:31:12Z DOI: 10.1080/13543784.2022.2008354
- A randomized, double-blind, placebo-controlled, single, and multiple
dose-escalation Phase I clinical trial to investigate the safety, pharmacokinetic, and pharmacodynamic profiles of oral S086, a novel angiotensin receptor-neprilysin inhibitor, in healthy Chinese volunteers-
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Authors: Yue Hu, Hong Zhang, Xiaojiao Li, Jiajia Mai, Lizhi Yang, Jie Yan, Ying Li, Jingchao Sun, Wenjie Xu, Shiying He, Jinfeng Li, Min Wu Pages: 1 - 9 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-11-08T08:05:02Z DOI: 10.1080/13543784.2021.1985464
- Latest generation estrogen receptor degraders for the treatment of hormone
receptor-positive breast cancer Open Access Article-
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Authors: Ya-Chi Chen, Jiajie Yu, Ciara Metcalfe, Tom De Bruyn, Thomas Gelzleichter, Vikram Malhi, Pablo D. Perez-Moreno, Xiaojing Wang Pages: 1 - 15 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-10-25T05:54:34Z DOI: 10.1080/13543784.2021.1983542
- The emerging role of immune checkpoint inhibitors for the treatment of
breast cancer Open Access Article-
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Authors: Frederick M. Howard, Dario Villamar, Gong He, Alexander T. Pearson, Rita Nanda Pages: 1 - 18 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-10-12T03:22:05Z DOI: 10.1080/13543784.2022.1986002
- Hepatitis D virus (HDV): investigational therapeutic agents in clinical
trials-
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Authors: Bilal Asif, Christopher Koh Pages: 1 - 16 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-10-01T08:34:15Z DOI: 10.1080/13543784.2021.1977795
- Investigational immunomodulatory drugs for enhancement of triple negative
breast cancer (TNBC) immunotherapy: early phase development-
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Authors: Paolo Tarantino, Gabriele Antonarelli, Liliana Ascione, Giuseppe Curigliano Pages: 1 - 15 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-09-27T05:54:15Z DOI: 10.1080/13543784.2021.1972968
- Giant cell arteritis: what is new in the preclinical and early clinical
development pipeline'-
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Authors: Patricia Harkins, Richard Conway Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Investigational Drugs PubDate: 2021-06-30T01:36:43Z DOI: 10.1080/13543784.2021.1940949
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