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- An update on nonhuman primate usage for drug and vaccine evaluation
against filoviruses-
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Authors: Marc-Antoine de La Vega Ara Xiii Shane Massey Jessica R. Spengler Gary P. Kobinger Courtney Woolsey a Galveston National Laboratory; Department of Microbiology Prevention, Atlanta, GA, USA Pages: 1 - 27 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-19T06:27:10Z DOI: 10.1080/17460441.2024.2386100
- Correction
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Pages: 1 - 1 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-19T02:58:52Z DOI: 10.1080/17460441.2024.2392351
- The discovery and development of gefapixant as a novel antitussive therapy
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Authors: Maria Gabriella Matera Paola Rogliani Clive P. Page Luigino Calzetta Mario Cazzola a Unit of Pharmacology; Department of Experimental Medicine, School of Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italyb Unit of Respiratory Medicine, Department Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italyc Institute of Pharmaceutical Science, King’s College London, London, UKd Unit of Respiratory Disease Surgery, University of Parma, Parma, Italy Pages: 1 - 14 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-14T05:37:21Z DOI: 10.1080/17460441.2024.2391902
- Perspectives on current approaches to virtual screening in drug discovery
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Authors: Ingo Muegge Jörg Bentzien Yunhui Ge Research department; Alkermes, Inc, Waltham, MA, USA Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-12T12:00:34Z DOI: 10.1080/17460441.2024.2390511
- Promising animal models for amyotrophic lateral sclerosis drug discovery:
a comprehensive update-
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Authors: Léa Lescouzères Shunmoogum A. Patten a INRS - Centre Armand Frappier Santé Biotechnologie; Laval, QC, Canadab Early Drug Discovery Unit, Montreal Neurological Institute-Hospital, McGill University, Montreal, Canadac Departement de Neurosciences, Université de Montréal, Montreal, Canada Pages: 1 - 21 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-08T01:05:25Z DOI: 10.1080/17460441.2024.2387791
- Approaches for the discovery of cinnamic acid derivatives with anticancer
potential-
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Authors: Dimitra Hadjipavlou-Litina Ioannis Fotopoulos Department of Pharmaceutical Chemistry; Aristotle University of Thessaloniki, Thessaloniki, Greece Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-06T12:25:15Z DOI: 10.1080/17460441.2024.2387122
- New horizons for obsessive-compulsive disorder drug discovery: is
targeting glutamate receptors the answer'-
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Authors: Giacomo Grassi Edoardo Scillitani Chiara Cecchelli Department of Psychiatry; Brain Center Firenze, Florence, Italy Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-06T12:23:15Z DOI: 10.1080/17460441.2024.2387127
- Molecular dynamics simulations for the structure-based drug design:
targeting small-GTPases proteins-
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Authors: Angela Parise Sofia Cresca Alessandra Magistrato Consiglio Nazionale delle Ricerche (CNR) - Istituto Officina dei Materiali (IOM); c/o International School for Advanced Studies (SISSA), Trieste, Italy Pages: 1 - 21 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-06T12:20:43Z DOI: 10.1080/17460441.2024.2387856
- Application of transporter assays for drug discovery and development: an
update of the literature-
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Authors: Donna A. Volpe Division of Applied Regulatory Science; Center for Drug Evaluation Drug Administration, Silver Spring, MD, USA Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-08-06T12:19:26Z DOI: 10.1080/17460441.2024.2387790
- Lessons learnt from broad-spectrum coronavirus antiviral drug discovery
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Authors: Andrew A. Bolinger Jun Li Xuping Xie Hongmin Li Jia Zhou a Chemical Biology Program; Department of Pharmacology Toxicology, R Ken Coit College of Pharmacy, The BIO5 Institute, The University of Arizona, Tucson, AZ, USA Pages: 1 - 19 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-30T11:46:31Z DOI: 10.1080/17460441.2024.2385598
- Targeting polo-like kinase 1: advancements and future directions in
anti-cancer drug discovery-
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Authors: Monika Raab Sven Becker Mourad Sanhaji School of Medicine; Department of Obstetrics Gynecology, J.W. Goethe University, Frankfurt, Germany Pages: 1 - 5 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-30T06:19:05Z DOI: 10.1080/17460441.2024.2385603
- How to address the complexity of multi-targeted drug discovery for
Alzheimer’s disease'-
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Authors: Juan F. González José M. Sánchez-Montero Department of Chemistry in Pharmaceutical Sciences; Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain Pages: 1 - 4 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-30T06:14:59Z DOI: 10.1080/17460441.2024.2385576
- Innovative drug discovery strategies in epilepsy: integrating
next-generation syndrome-specific mouse models to address pharmacoresistance and epileptogenesis-
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Authors: Melissa Barker-Haliski Nicole A Hawkins a Pharmaceutics; University of Washington, Seattle, WA, USAb Feinberg School of Medicine Chicago, Northwestern University, Chicago, IL, USA Pages: 1 - 15 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-30T06:13:21Z DOI: 10.1080/17460441.2024.2384455
- The value of protein allostery in rational anticancer drug design: an
update-
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Authors: Ruth Nussinov Hyunbum Jang a Computational Structural Biology Section; Frederick National Laboratory for Cancer Research in the Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD, USAb Department of Human Molecular Genetics Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Pages: 1 - 15 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-28T02:17:59Z DOI: 10.1080/17460441.2024.2384467
- Complementary strategies to be used in conjunction with animal models for
multiple sclerosis drug discovery: adapting preclinical validation of drug candidates to the need of remyelinating strategies-
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Authors: Imane Charmarke-Askar Caroline Spenlé Dominique Bagnard INSERM ERL1321; Biothérapies Peptidiques, Illkirch, France Pages: 1 - 10 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-23T05:06:58Z DOI: 10.1080/17460441.2024.2382180
- What impact does tautomerism have on drug discovery and development'
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Authors: Devendra K. Dhaked Marc C. Nicklaus a Department of Pharmacoinformatics; National Institute of Pharmaceutical Education Research (NIPER), Kolkata, Indiab Computer-Aided Drug Design Group, Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD, USA Pages: 1 - 6 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-17T05:18:09Z DOI: 10.1080/17460441.2024.2379873
- Polypharmacology prediction: the long road toward comprehensively
anticipating small-molecule selectivity to de-risk drug discovery-
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Authors: Leticia Manen-Freixa Albert A. Antolin a Oncobell Division; Bellvitge Biomedical Research Institute (IDIBELL) ProCURE Department, Catalan Institute of Oncology (ICO), Barcelona, Spainb Center for Cancer Drug Discovery, The Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK Pages: 1 - 27 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-15T05:47:36Z DOI: 10.1080/17460441.2024.2376643
- Inhibitors and PROTACs of CDK2: challenges and opportunities
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Authors: Yangjie Zeng Xiaodong Ren Pengyao Jin Zhida Fan Mengguang Liu Yali Zhang Linzhao Li Ming Zhuo Jubo Wang Zhiyu Li Min Wu a Medical College; Guizhou University, Guiyang, Chinab Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, Chinac Department of Neurosurgery, Guizhou Provincial People’s Hospital, Guiyang, China Pages: 1 - 24 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-12T09:09:09Z DOI: 10.1080/17460441.2024.2376655
- How to correctly develop q-RASAR models for predictive cheminformatics
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Authors: Arkaprava Banerjee Kunal Roy Drug Theoretics; Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India Pages: 1 - 6 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-05T08:14:21Z DOI: 10.1080/17460441.2024.2376651
- An update on the novel methods for the discovery of antiseizure and
antiepileptogenic medications: where are we in 2024'-
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Authors: Alan Talevi Carolina Bellera a Laboratory of Bioactive Compound Research; Development (LIDeB), Faculty of Exact Sciences, University of La Plata (UNLP), La Plata, Argentinab Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), CCT La Plata, La Plata, Argentina Pages: 1 - 16 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-04T11:35:46Z DOI: 10.1080/17460441.2024.2373165
- Recent developments in the application of immobilized artificial membrane
(IAM) chromatography to drug discovery-
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Authors: Fotios Tsopelas Theodosia Vallianatou Anna Tsantili-Kakoulidou a Laboratory of Inorganic; Kapodistrian University of Athens, Athens, Greece Pages: 1 - 12 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-07-03T07:17:46Z DOI: 10.1080/17460441.2024.2374409
- The preclinical discovery and development of zolbetuximab for the
treatment of gastric cancer-
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Authors: Yongji Zeng A. Craig Lockhart Ramon U. Jin a Section of Gastroenterology; Department of Medicine, Baylor College of Medicine, Houston, USAb Division of Hematology/Oncology, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina, USAc Section of Hematology/Oncology, Department of Medicine, Baylor College of Medicine, Houston, USA Pages: 1 - 14 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-26T07:37:54Z DOI: 10.1080/17460441.2024.2370332
- An update on lipophilic efficiency as an important metric in drug design
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Authors: Rebecca A. Gallego Martin P. Edwards T. Patrick Montgomery Oncology; Pfizer Inc, San Diego, CA, USA Pages: 1 - 15 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-26T07:36:06Z DOI: 10.1080/17460441.2024.2368744
- Unveiling dynamics of nitrogen content and selected nitrogen heterocycles
in thrombin inhibitors: a ceteris paribus approach-
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Authors: Vijay H. Masand Sami Al-Hussain Abdullah Y. Alzahrani Aamal A. Al-Mutairi Arwa Sultan Alqahtani Abdul Samad Ahmed M. Alafeefy Rahul D. Jawarkar Magdi E.A. Zaki a Department of Chemistry; Vidya Bharati Mahavidyalaya, Amravati, Indiab Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabiac Department of Chemistry, Faculty of Science Drug Discovery, Dr Rajendra Gode Institute of Pharmacy, Amravati, India Pages: 1 - 19 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-20T05:53:27Z DOI: 10.1080/17460441.2024.2368743
- Phage display technology and its impact in the discovery of novel
protein-based drugs-
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Authors: Catherine J. Hutchings Aaron K. Sato a Independent Consultant; UKb Twist Bioscience, South San Francisco, USA Pages: 1 - 29 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-19T05:43:29Z DOI: 10.1080/17460441.2024.2367023
- Artificial intelligence for small molecule anticancer drug discovery
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Authors: Lihui Duo Yu Liu Jianfeng Ren Bencan Tang Jonathan D. Hirst a Faculty of Science; Engineering, University of Nottingham Ningbo China, Ningbo, Chinab School of Chemistry, University of Nottingham University Park, Nottingham, UK Pages: 1 - 16 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-19T04:57:13Z DOI: 10.1080/17460441.2024.2367014
- Targeting guanine nucleotide exchange factors for novel cancer drug
discovery-
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Authors: Sahar F. Bannoura Husain Yar Khan Md. Hafiz Uddin Ramzi M. Mohammad Boris C. Pasche Asfar S. Azmi Department of Oncology; Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA Pages: 1 - 11 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-17T12:20:14Z DOI: 10.1080/17460441.2024.2368242
- The coming of age of cyclic peptide drugs: an update on discovery
technologies-
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Authors: Sophia You Glen McIntyre Toby Passioura a Insamo South; Chippendale, NSW, Australiab School of Chemistry, The University of Sydney, Camperdown, NSW, Australia Pages: 1 - 13 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-14T07:41:09Z DOI: 10.1080/17460441.2024.2367024
- The latest trends in peptide drug discovery and future challenges
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Authors: Laszlo Otvos a OLPE Pharmaceutical Consultants; Audubon, USAb The Institute for Microbiology, Semmelweis University, Budapest, Hungary Pages: 1 - 4 Abstract: .
Citation: Expert Opinion on Drug Discovery PubDate: 2024-06-11T12:19:46Z DOI: 10.1080/17460441.2024.2365969
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