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  Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
Showing 401 - 253 of 253 Journals sorted alphabetically
Microbial Drug Resistance     Hybrid Journal   (Followers: 3)
Molecular Informatics     Hybrid Journal   (Followers: 5)
Molecular Pharmacology     Hybrid Journal   (Followers: 2)
Molekul     Open Access  
Natural Product Communications     Open Access  
Nature Reviews Drug Discovery     Full-text available via subscription   (Followers: 311)
Naunyn-Schmiedeberg's Archives of Pharmacology     Hybrid Journal  
NeuroMolecular Medicine     Hybrid Journal  
Neuropharmacology     Hybrid Journal   (Followers: 5)
Neuropsychopharmacology     Hybrid Journal   (Followers: 17)
Neuropsychopharmacology Reports     Open Access  
Nigerian Journal of Natural Products and Medicine     Full-text available via subscription  
OA Drug Design & Delivery     Open Access  
OA Medical Hypothesis     Open Access  
Obesity Facts     Open Access   (Followers: 8)
Open Pharmacoeconomics & Health Economics Journal     Open Access   (Followers: 1)
Open Pharmacology Journal     Open Access  
OpenNano     Open Access   (Followers: 1)
Orbital - The Electronic Journal of Chemistry     Open Access   (Followers: 1)
Oriental Pharmacy and Experimental Medicine     Partially Free   (Followers: 2)
Pain and Therapy     Open Access   (Followers: 3)
Particulate Science and Technology: An International Journal     Hybrid Journal   (Followers: 1)
PDA Journal of Pharmaceutical Science and Technology     Full-text available via subscription   (Followers: 34)
Pediatric Drugs     Full-text available via subscription   (Followers: 3)
Pediatric Pharmacology     Open Access   (Followers: 1)
Pharmaceutica Analytica Acta     Open Access  
Pharmaceutical Biology     Open Access  
Pharmaceutical Care-La Farmacoterapia     Open Access  
Pharmaceutical Chemistry Journal     Hybrid Journal  
Pharmaceutical Development and Technology     Hybrid Journal   (Followers: 19)
Pharmaceutical Executive     Full-text available via subscription   (Followers: 2)
Pharmaceutical Fronts     Open Access   (Followers: 9)
Pharmaceutical Historian     Open Access  
Pharmaceutical Journal     Free   (Followers: 8)
Pharmaceutical Journal of Sri Lanka     Open Access  
Pharmaceutical Medicine     Full-text available via subscription   (Followers: 4)
Pharmaceutical Nanotechnology     Hybrid Journal  
Pharmaceutical Patent Analyst     Full-text available via subscription   (Followers: 3)
Pharmaceutical Research     Hybrid Journal   (Followers: 93)
Pharmaceutical Statistics     Hybrid Journal   (Followers: 15)
Pharmaceutical Technology     Full-text available via subscription   (Followers: 7)
Pharmaceuticals     Open Access   (Followers: 4)
Pharmacia     Open Access  
Pharmaciana     Open Access  
PharmacoEconomics     Full-text available via subscription   (Followers: 25)
PharmacoEconomics & Outcomes News     Full-text available via subscription   (Followers: 2)
PharmacoEconomics German Research Articles     Full-text available via subscription  
PharmacoEconomics Spanish Research Articles     Hybrid Journal   (Followers: 1)
Pharmacoepidemiology and Drug Safety     Hybrid Journal   (Followers: 33)
Pharmacogenetics and Genomics     Hybrid Journal   (Followers: 1)
Pharmacogenomics     Hybrid Journal   (Followers: 7)
Pharmacogenomics and Personalized Medicine     Open Access   (Followers: 2)
Pharmacogenomics Journal     Hybrid Journal   (Followers: 5)
Pharmacognosy Communications     Partially Free  
Pharmacognosy Magazine     Open Access   (Followers: 2)
Pharmacognosy Research     Open Access   (Followers: 2)
Pharmacological Reports     Hybrid Journal  
Pharmacological Research     Hybrid Journal   (Followers: 1)
Pharmacological Research - Modern Chinese Medicine     Open Access  
Pharmacological Reviews     Hybrid Journal   (Followers: 2)
Pharmacology     Full-text available via subscription  
Pharmacology & Therapeutics     Hybrid Journal   (Followers: 3)
Pharmacology & Pharmacy     Open Access   (Followers: 1)
Pharmacology Biochemistry and Behavior     Hybrid Journal   (Followers: 2)
Pharmacology Research & Perspectives     Open Access  
Pharmacon : Jurnal Farmasi Indonesia     Open Access  
Pharmacopsychiatry     Hybrid Journal   (Followers: 3)
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy     Hybrid Journal   (Followers: 37)
Pharmactuel     Open Access   (Followers: 1)
Pharmacy     Open Access   (Followers: 4)
Pharmacy & Pharmacology     Open Access   (Followers: 1)
Pharmacy Education     Full-text available via subscription   (Followers: 11)
Pharmacy Practice (Internet)     Open Access   (Followers: 8)
Pharmakon : Arzneimittel in Wissenschaft und Praxis     Full-text available via subscription   (Followers: 1)
PharmaNutrition     Hybrid Journal   (Followers: 3)
PharmaTutor     Open Access  
Pharmazeutische Industrie     Full-text available via subscription   (Followers: 9)
Pharmazeutische Zeitung     Full-text available via subscription   (Followers: 11)
Pharmazie in Unserer Zeit (Pharmuz)     Hybrid Journal   (Followers: 11)
Physiology International     Full-text available via subscription   (Followers: 3)
Plant Products Research Journal     Full-text available via subscription  
Planta Medica     Hybrid Journal   (Followers: 4)
Planta Medica International Open     Open Access  
Prescriber     Hybrid Journal   (Followers: 9)
Progress in Neuro-Psychopharmacology and Biological Psychiatry     Hybrid Journal   (Followers: 8)
Psychiatry and Clinical Psychopharmacology     Open Access   (Followers: 1)
Psychopharmacology     Hybrid Journal   (Followers: 15)
Pulmonary Pharmacology & Therapeutics     Hybrid Journal   (Followers: 2)
PZ Prisma : Materialien zur Fort- und Weiterbildung     Full-text available via subscription  
Redox Report     Open Access  
Regulatory Mechanisms in Biosystems     Open Access   (Followers: 1)
Regulatory Toxicology and Pharmacology     Hybrid Journal   (Followers: 41)
Research & Reviews : A Journal of Drug Design & Discovery     Full-text available via subscription  
Research & Reviews : A Journal of Pharmaceutical Science     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacognosy     Full-text available via subscription  
Research & Reviews : A Journal of Pharmacology     Full-text available via subscription   (Followers: 1)
Research in Pharmaceutical Sciences     Open Access   (Followers: 3)
Research in Social and Administrative Pharmacy     Hybrid Journal   (Followers: 3)
Research Journal of Pharmacognosy     Open Access  
Research Results in Pharmacology     Open Access  
Reviews of Physiology, Biochemistry and Pharmacology     Hybrid Journal   (Followers: 4)
Reviews on Clinical Pharmacology and Drug Therapy     Full-text available via subscription  
Revista Colombiana de Ciencias Químico-Farmacéuticas     Open Access  
Revista Cubana de Plantas Medicinales     Open Access   (Followers: 1)
Revista de Ciências Farmacêuticas Básica e Aplicada     Open Access  
Revista Mexicana de Ciencias Farmaceuticas     Open Access  
Revue de Médecine et de Pharmacie     Full-text available via subscription  
Safety and Risk of Pharmacotherapy     Open Access   (Followers: 1)
Saudi Pharmaceutical Journal     Open Access  
Scandinavian Journal of Clinical and Laboratory Investigation     Hybrid Journal   (Followers: 7)
Scientia Pharmaceutica     Open Access  
Seminars in Hematology     Hybrid Journal   (Followers: 12)
Seminars in Oncology Nursing     Full-text available via subscription   (Followers: 10)
Separation Science plus (SSC plus)     Hybrid Journal  
Side Effects of Drugs Annual     Full-text available via subscription   (Followers: 2)
Skin Pharmacology and Physiology     Full-text available via subscription   (Followers: 6)
Substance Abuse : Research and Treatment     Open Access   (Followers: 5)
Suchttherapie     Hybrid Journal   (Followers: 1)
Sustainable Chemistry and Pharmacy     Full-text available via subscription   (Followers: 1)
Synfacts     Hybrid Journal   (Followers: 5)
SynOpen     Open Access  
The Botulinum J.     Hybrid Journal  
The Brown University Psychopharmacology Update     Hybrid Journal   (Followers: 2)
The Medical Letter     Full-text available via subscription   (Followers: 18)
The Pink Sheet     Full-text available via subscription   (Followers: 13)
The Pink Sheet Daily     Full-text available via subscription   (Followers: 4)
Therapeutic Advances in Drug Safety     Open Access   (Followers: 3)
Therapeutic Advances in Psychopharmacology     Open Access   (Followers: 4)
Therapeutic Advances in Vaccines     Hybrid Journal   (Followers: 1)
Therapeutic Drug Monitoring     Hybrid Journal   (Followers: 3)
Therapeutic Innovation & Regulatory Science     Hybrid Journal   (Followers: 7)
Thérapie     Full-text available via subscription   (Followers: 1)
TheScientist     Free   (Followers: 5)
Toxicological & Environmental Chemistry     Hybrid Journal   (Followers: 2)
Toxicological Research     Hybrid Journal  
Toxicological Sciences     Hybrid Journal   (Followers: 11)
Toxicology     Hybrid Journal   (Followers: 18)
Toxicology and Applied Pharmacology     Hybrid Journal   (Followers: 24)
Toxicology and Industrial Health     Hybrid Journal   (Followers: 6)
Toxicology in Vitro     Hybrid Journal   (Followers: 11)
Toxicology International     Full-text available via subscription   (Followers: 5)
Toxicology Letters     Hybrid Journal   (Followers: 15)
Toxicology Mechanisms and Methods     Hybrid Journal   (Followers: 7)
Toxicology Research     Partially Free   (Followers: 8)
Toxicon     Hybrid Journal   (Followers: 5)
Toxicon : X     Open Access  
Toxin Reviews     Hybrid Journal  
Translational Psychiatry     Open Access   (Followers: 14)
Trends in Peptide and Protein Sciences     Open Access  
Trends in Pharmacological Sciences     Full-text available via subscription   (Followers: 19)
Tropical Journal of Pharmaceutical Research     Open Access  
Ukrainian Biopharmaceutical Journal     Open Access  
Vascular Pharmacology     Hybrid Journal   (Followers: 2)
World Mycotoxin Journal     Hybrid Journal   (Followers: 3)
Yakugaku Zasshi     Open Access   (Followers: 1)
Zeitschrift für Phytotherapie     Hybrid Journal   (Followers: 1)
Актуальні питання фармацевтичної та медичної науки та практики     Open Access  
Фармацевтичний часопис     Open Access  

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International Journal of Green Pharmacy
Journal Prestige (SJR): 0.142
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0973-8258 - ISSN (Online) 1998-4103
Published by Medknow Publishers Homepage  [448 journals]
  • Development and characterization of anti-diabetic liposomal formulation

    • Authors: K. Florence Rachel
      Abstract: Introduction: Diabetes is a chronic health condition that affects how human body turns food into energy. It is most commonly occurring disease. Liposomal technology has been employed for the flourishing encapsulation of various drug molecules and oral route of administration is much more convenient. The main aim was to develop and characterize oral antidiabetic liposomal formulation. Further, prepared liposomal formulations evaluated for particle size, % drug release, differential scanning calorimetry (DSC), Fourier transform infrared, in vitro release, release kinetics model, animal studies, and experimental data subjected to statistical testing using one-way analysis of variance followed by Dunnett test were carried out. Materials and Methods: The liposomal formulations were formulated using thin-film hydration technique. Sitagliptin liposomal formulations (F1-F6) were prepared by employing soy lecithin and cholesterol in varying concentration. Results: In vitro release of different antidiabetic liposomal formulations was performed and observed through cellophane membrane using Franz Diffusion cell. The finalized liposomal formulation (F6) showed better release. To check the antihyperglycemic activity was performed using oral glucose tolerance test using Sprague Dawley (SD) rats for the optimized formulation. Finalized formulation (F6) elicited the better in-vitro release 87.85% at 8 h in comparison with the pure drug release was initiate to be 59.57%. Particle size distribution and zeta potential were found to be 40 nm as well as 40 mV, respectively. In vitro release kinetic models were shown that it follows first-order kinetics and high regression coefficient r2 value was 0.975. The DSC thermogram of sitagliptin was found 221.7°C. The DSC thermogram of physical mixture of cholesterol along with soy lecithin was found to be 42.1°C and 220.3°C. DSC analysis confirmed that there was negative interaction between the drug and excipients. Discussion and Conclusion: It would be concluded that antidiabetic liposomal formulation using sitagliptin as drug, soy lecithin and cholesterol as polymer can be formulated thereby can enhance oral bio-availability. The optimized formulation (F6) has shown best formulation based on the in vitro drug release. In vivo studies for the optimized formulation (F6) observed that sitagliptin was found to be more potent than sitagliptin marketed formulation and activity was persisted till 4 h.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3221
      Issue No: Vol. 16, No. 1 (2022)
       
  • Green synthesis of silver nanoparticles using flower extract of Calliandra
           haematocephala, screening of antibacterial and antioxidant activities

    • Authors: B. N. B. Vaidehi
      Abstract: Aim: Green synthesis of silver nanoparticles (AgNPs) was gained more importance comparative with other methods due to their salient features such as simplicity in procedure, non-toxic by-products, and cost effective; rapidity. Among the different types of nanoparticles, AgNPs have received more focus due to their unique antimicrobial properties. Materials and Methods: We successfully synthesized AgNPs from an aqueous flower extract of the Calliandra haematocephala plant for the first time. Thus, synthesized AgNPs were characterized by ultraviolet-visible spectroscopy and the surface Plasmon resonance peak was identified to be 451 nm. The key chemical features responsible for the reduction of silver nitrate to form AgNPs and the capping agents present in the flower extract were identified by Fourier-transform infrared spectroscopy. The synthesized AgNPs (0.1, 0.2, 0.3, 0.4, 0.5mM) were screened for antibacterial activity by cup-plate method and antioxidant activities by H2O2 Scavenging assay, and Phosphomolybdenum Method. Results: On phytochemical screening of aqueous flower extract of C. haematocephala, it was revealed that various phytoconstituents such as alkaloids, flavonoids, tannins, and saponins, and cardiac glycosides were present. The potent antibacterial and antioxidant activity were identified at 0.5 mM AgNPs solution. Conclusion: The overall results confirmed that aqueous flower extract of C. haematocephala plant possess good antibacterial and antioxidant activity.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3222
      Issue No: Vol. 16, No. 1 (2022)
       
  • Pharmacognostical evaluation of Arisaema murrayi (J. Graham) Hook. leaves
           and tubers for quality control assessment

    • Authors: Ennus Tajuddin Tamboli
      Abstract: Introduction: Arisaema murrayi (J. Graham) Hook. is one of the plants belonging to the family Araceae, commonly
      called Murray’s Cobra Lily or Snake Lily which is known for its medicinal benefits. However, no published work
      is available to date on pharmacognostical evaluation. Materials and Methods: Pharmacognostic evaluation of
      leaf sand tubers was carried as per the standard guidelines which are based on morphological, microscopical, and
      physicochemical analysis. Results: The morphological evaluation of tubers revealed that tubers were hemispheric
      in shape, up to 5 cm radius, leaves were found to be coming up shortly after the peduncle, with peltate shape. The
      layers of the epidermis in the leaf are closely packed. Below the epidermis, there is 2–3 layer of collenchyma cells
      present. Microscopy study of powder showed the presence of a few layers of fibrous tissue. Cluster crystals of calcium
      oxalate and starch grains were also present in the powder. Preliminary phytochemical analysis showed the presence of
      carbohydrates, proteins and amino acids as primary metabolites, and alkaloids as secondary metabolites. Conclusion:
      Pharmacognostic characters studied will be helpful in morphological and microscopical standardization of A. murrayi.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3223
      Issue No: Vol. 16, No. 1 (2022)
       
  • Comparative studies on several Vidanga plants collected from Maharashtra,
           India, employing phytochemical screening, high-performance thin-layer
           chromatography analysis, and anti-oxidant potential

    • Authors: Suresh Jagtap
      Abstract: Introduction: Vidanga is a well-known herbal treatment that has been used to treat a range of ailments for ages. According to modern literature, Vidanga is most commonly used to treat inflammation especially gut inflammation, namely colitis. Embelin is the major bioactive compound present in Vidanga (Embelia spp.) responsible for its therapeutic property. According to Ayurveda, Embelia ribes is the indicated botanical as a “Vidanga” but under the name, “Vidanga” four plants are marketed, namely, Embelia drupacea (Dennst.) M. R. Almeida and S. M. Almeida, E. ribes Burm. f. and Maesa indica (Mi) (Roxb.) A. DC., Embelia tsjeriam-cottam (Etj) (Roem. and Schult.) A. DC and Mi (Roxb.) A. DC. Hence, it is necessary to identify a therapeutically more effective plant as Vidanga. Materials and Methods: We have evaluated more effective species using phytochemical screening; high-performance thin-layer chromatography (HPTLC) characterization; and free radical scavenging potential using bovine serum albumin (BSA) anti-denaturation assay, nitric oxide scavenging (NOS) activity, and 2,2’-Azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) assay. Results: Preliminary phytochemical analysis indicated the presence of quinone, carbohydrates, fixed oils, glycosides, terpenoids, steroids, and tannins in collected Vidanga samples. HPTLC studies revealed that Embelin levels were highest in Etj (1.06 ng/μl), followed by E. ribes (Er) (0.92 ng/μl), E. drupacea (Ed) (0.5 ng/μl), and absent in Maesa indica (Mi). Er exhibited better anti-denaturation activity than Etj, Ed, and Mi. Etj and Er showed a superior ABTS scavenging activity than Ed and Mi. NOS antioxidant activity was also shown to be higher in Er and Etj than in Ed and Mi. Discussion and Conclusion: Phytochemicals have been found in all plant species, although, HPTLC screening revealed that Er and Etj have similar quantities of Embelin. The antioxidant properties were strongly linked to the Embelin content, indicating that Er and Etj might be a viable substitution for one another.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3224
      Issue No: Vol. 16, No. 1 (2022)
       
  • Phyto-physicochemical and high-performance thin layer chromatography
           investigation of root of Cadaba farinosa, Forsk

    • Authors: Prof. U. B. Telrandhe
      Abstract: Background: Cadaba farinosa, Forsk belongs to family Capparidaceae, traditionally used for a variety of medicinal purposes. Despite of its popular medicinal utilization, still no conclusive study has been reported so far regarding the pharmacognostical standardization. Objective: The present investigation was focused to scientifically establish the standard monograph of C. farinosa on the basis of its physicochemical and phytochemical parameters. Materials and Methods: Various physicochemical parameters such as ash values, extractive values, foreign organic matter, moisture content, reaction of powdered drug with different chemicals, and fluorescence analysis of C. farinosa were determined for ascertaining the quality of crude drug. The preliminary qualitative and quantitative phytochemical analysis, various inorganic minerals, and heavy metals along with high-performance thin layer chromatography (HPTLC) of C. farinosa were performed. Results: The physicochemical parameters were established. The various phytochemicals such as phenolic compounds, alkaloids, flavonoids, glycosides, and tannins were present in both ethyl acetate and aqueous extract, while sugars and carbohydrates, protein, amino acid, saponin, gums, and mucilage were present in aqueous extract. Steroids are only present in ethyl acetate extract. Terpenoid, fixed oil, and fats were absent in both the extracts. Various inorganic minerals and heavy metals were present in C. farinosa. The HPTLC fingerprinting of various phytochemical in ethyl acetate extract was done. Conclusion: The obtained data would serve as a useful guide toward establishing pharmacognostic standards, identification, assessing purity, standardization, and preparation of monograph of C. farinosa.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3225
      Issue No: Vol. 16, No. 1 (2022)
       
  • High-amylose maize starch as a novel film former to develop oral films
           with excellent mechanical properties: A preliminary study

    • Authors: Mrs. Vijayalakshmi Sankaranarayanan
      Abstract: Aim: The study involved the development and optimization of the fast-dissolving oral films of salbutamol sulfate
      using high-amylose maize starch (HAMS) as a novel film former by comparison with the HPMC E50 (hydroxy
      propyl methyl cellulose) films. The high aqueous solubility, low dose, and low molecular weight of salbutamol
      sulfate make it best suited for oral dissolving films, thereby possible to enhance patient compliance in pediatrics
      and geriatrics. Materials and Methods: The HPMC E50 and HAMS films were prepared by solvent-casting
      technique. The casted films were optimized using the design of experiments employing 22 factorial designs with
      replicates separately. The concentration of HAMS/HPMC and crospovidone were considered as independent
      variables and the responses being tensile strength (TS), percentage elongation at break, and disintegration
      time. Results and Discussion: HAMS films exhibited good mechanical properties due to high TS and greater
      percentage elongation than the HPMC E50 films. Both the films disintegrated within a minute with no significant
      differences. X-ray diffraction studies exposed that starch with high-amylose content has a greater crystalline
      domain and this may be attributed to the maximum TS of the formulated HAMS oral films. In vitro drug dissolution
      profiles of HAMS and HPMC E50 films at the end of 10 min were found to be 96.98% and 88.25%, respectively.
      Conclusion: From this study, it is evident that HAMS can be utilized as the promising film-forming polymer in
      the development of fast-dissolving oral films.
      PubDate: 2022-04-29
      DOI: 10.22377/ijgp.v16i1.3226
      Issue No: Vol. 16, No. 1 (2022)
       
  • Jawarish jalinoos: A polyherbal unani formulation for gastrointestinal
           disorders

    • Authors: Mohd Aleem
      Abstract: Introduction: Murakkab drugs of Unani medicine has been an important aspect of disease treatment since antiquity. Physicians prepared different formulations for various diseases. Jawarish Jalinoos is an Unani polyherbal formulation listed under the Majooniath category in the National Formulary of Unani Medicine, Part-I. It has a long history of traditional use for the management of several disorders related to gastrointestinal, cardiac, kidney, metabolism, and general health. The present study examined the effects of Jawarish Jalinoos in gastrointestinal and other disorders. Materials and Methods: Empirical searches were conducted on the medicinal plant via significant search engines such as Google Scholar, Scopus, PubMed, Microsoft academic, and Web of Science from inception up to July 2021. Besides, references from classical Unani literature and books, non-English journals were also included. Results: The ingredients of Jawarish Jalinoos contain, almost all, more or less, essential oils and their essential oil value should give a reliable therapeutic index. Its ingredients contain α- pinene, β- pinene, limonene, jatamansone, α-terpinyl acetate, eugenol, linalool, coumarin, gingerols, monoterpenes, sesquiterpenes, shogaols, etc., which possesses potent antimicrobial, anti-inflammatory, gastroprotective, neuroprotective, and antioxidant properties. Discussion and Conclusion: Till now, not a single study has been done on its pharmacological properties. According to different Unani Qarabadeen’s (Pharmacopoeias) this formulation is used in various ailments such as Zo’f-ī -Azae-Raeesa (weakness of the principle organs such as brain, heart, and liver), Zo’f-ī-mi’da (stomach weakness), Nafakh-ī-Shikam (flatulence), Khafqān (palpitation), Haemorrhoids, Tinea, Niqras (Gout), Sang-ī-Gurdā (Renal calculus), Sang-ī-Mathānā (Vesicular calculus), but scientific studies and clinical trials are needed on this compound formulation to ensure its scientific validation.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3210
      Issue No: Vol. 16, No. 1 (2022)
       
  • Therapeutic and insecticidal potential of plant terpenes: A review

    • Authors: Dr. Ravi Kant Upadhyay
      Abstract: Present article describes therapeutic and insecticidal activities of plant terpenes. Volatile terpenes and
      terpenophenolics were found highly active against protozoa, viruses, bacteria, and helminthes. Terpenes also
      display bacteriostatic, bactericidal, and virucidal activities. These potentially function like promising natural
      insecticides and were found active against houseflies, storage grain insects and medical pests. Terpenes are
      strongest anti-parasitic natural products which could be used for development of formulations for oral delivery.
      These quickly absorbed in the stomach, and show reducing dosage and toxic side effects. Terpenoids as largest
      group of bio-organic compounds are safer, show high efficacy and no side effects when applied in field or
      provided for therapeutic purposes. This article suggests use of various terpenoids for development of herbal drug
      formulations for disease control after determining clinical and therapeutic dose level.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3211
      Issue No: Vol. 16, No. 1 (2022)
       
  • Asgand (Withania somnifera (L.) Dunal - A prophylactic and
           immune-modulator AYUSH-Unani botanical drug

    • Authors: Dr Mohd Kashif Husain
      Abstract: Withania somnifera (L.) Dunal is a valuable plant of family Solanaceae, which is commonly known as Asgand
      in Unani system of medicine (Tibb-e-Unani). The plant is found throughout the drier parts of India and other
      parts of the world. The main drug component comprises of the roots that is used for its therapeutic actions either
      singly or as an ingredient in compound formulations. Asgand is well described in Unani classics as Musakkin
      (sedative), Muqawwi (tonic) Muhallil-e-waram (anti-inflammatory), Muaddil (alterative), and Muqawwi-e-Bah
      (aphrodisiac). In Unani system, it is prescribed for rheumatism, gynecological disorders, cough, hiccup dropsy,
      and as a sedative in cases of senile debility. Studies indicate that the pharmacological activities of the root and
      leaf are attributed to the presence of several alkaloids and steroidal lactones including withanine, somniferine,
      somnine, and somniferinine. Leaves contain a group of (nearly twelve) “Withanolides” including “Withaferin-A”
      with antibiotic and anti-tumor activity. Asgand possesses anti-inflammatory, antioxidant, anxiolytic, adaptogenic,
      memory enhancing, antiparkinsonian, and antitumor properties. Several other effects such as immuno-modulation,
      cardiovascular protection, hypolipidemic, antibacterial, and sexual behavior, tolerance have also been studied. In
      conventional Unani system, enhancing immunity with immune-boosters is one of the key approaches for prevention
      of disease and maintenance of health. An attempt has been made in this review to explore the various dimensions
      of the drug viz; morphological, pharmacological, chemical studies and more specifically the therapeutic actions,
      uses and Unani perspective of Asgand in the time of Covid-19.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3212
      Issue No: Vol. 16, No. 1 (2022)
       
  • Pharmacological activities and bioactive compounds of papaya (Carica
           papaya L.): A mini topical review

    • Authors: R. Nirmala
      Abstract: The present review focuses on the pharmacological activities and bioactive compounds of Carica papaya L. The
      plant is well known to us since ancient times. The plant is traditionally used to treat several conditions such as
      stomach disorders, diarrhea skin diseases, male contraceptives, and home remedies for colds. Phytochemically,
      the plants have alkaloids, tannins, flavonoids, saponins, glycosides, starch, quinones, etc. Various medicine
      properties attributed to the plant and parts which include antimicrobial, antioxidant, anti-diabetic, anti-cancer,
      anti-inflammatory, anti-hypertensive, anti-amoebic, anti-malarial, wound healing, anti-fertility, hepatoprotective,
      histaminergic, diuretic, immuno-modulatory, and anti-ulcer. In this review article, we have collectively summarized
      various pharmacological applications of C. papaya L.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3213
      Issue No: Vol. 16, No. 1 (2022)
       
  • Anti-termite and therapeutic uses of various plant essential oils from
           family Rutaceae: A review

    • Authors: Dr. Ravi Kant Upadhyay
      Abstract: This review article explains the use of various plant essential oils (EOs) and its formulations in termite control.
      Plant EOs and its components show multiple deleterious effects such as toxic, antifeedant, repellent, growth, and
      reproductive inhibitory activity in number of insect pest species. These active components delay egg maturation
      and development in insects. Plant EOs constituents display contact and systemic action and primarily used as
      poison baits to control soil termite. This article points out the importance of the use of plant origin termiticides/
      biopesticides and botanical methods to control termite menace. These alternate methods could be used to minimize
      the risk of poisoning of food chain, soil, and aqueous environment. This article also suggests wider use of EO-based
      multicomponent low-cost anti-termite formulations/methods to replace highly toxic synthetic pesticides.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3214
      Issue No: Vol. 16, No. 1 (2022)
       
  • A systematic review on multi-nutritional and phytopharmacological
           importance of Perilla frutescens

    • Authors: Dr. Rehan S. Ahmad
      Abstract: Perilla frutescens (L.) Britt, a worldwide distributed plant, is an important economic crop and with a long cultivation history in China as well as some other countries in Asia. The plant species were the main parts of folk medicine practiced by the ancient peoples in different parts of the world. P. frutescens (L.) is an annual short-day plant belonging to the family Labiatae which is used by ancient people in different parts of the world. P. frutescens have been used as an important traditional herbal medicine for treating various diseases including depression, anxiety, tumor, cough, antioxidant, allergy, intoxication, and some intestinal disorders. Perilla seeds contain considerably high levels (approx. 60%) of α-linolenic acid, which can be expected to possess various biological activities. The leaves are said to be helpful for asthma, colds, and different types of flu’s. The current review has been written after gone through several literature of review on P. frutescens and a great effort have been given to enhance the pharmacological contents in the current review from different literature of review. The current review included many bioactive metabolites present in P. frutescens and their nutritional as well as pharmacological importance.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3215
      Issue No: Vol. 16, No. 1 (2022)
       
  • A critical review on Nidra (sleep) in the light of Brihattrayi (greater
           trio of ayurveda literature)

    • Authors: Kunal Ojha
      Abstract: Sleep and health are often talked about together as good sleep is essential for good health. Sleep is related to all the aspects of human health, it provides satisfaction (happiness and sorrow), alertness (knowledge and unawareness), body nourishment, etc. The phenomenon of sleep is still in the ambit of ambiguity, and partial success can be claimed regarding the facts gathered by years of research, experiments and experiences. The concept and the details provided Ayurvedic texts can help in answering the various questions related sleep, sleep health, etc. Sleep health is an important part when health is being studied, epidemiological studies suggest that improper of disturbed sleep is part of pathogenesis of many diseases. Acharya Sushruta has regarded night sleeps one among the Ekantahitakara Viharas (absolutely whole some regimen conducive to better maintenance of health). Effect of sleep on the health depends on the timings of sleeping and waking up, efficiency of the sleep, and the duration. Improper sleep like day sleep, Prajagarana contraindicated and manifested of diseases. Hence, the present review work is aimed to explore the potentials of Nidra in disease and health conditions dealt in the Ayurvedic literature in context to Brihattrayi (Greater trio of Ayurveda classics).
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3216
      Issue No: Vol. 16, No. 1 (2022)
       
  • Phytochemistry and Ethno Biological discussion of Ajos sacha

    • Authors: Devid Chutia
      Abstract: Introduction: Plants have been utilized as a source of medicine for a long time. Scientists have successfully mended several abnormal health disorders by boosting traditional pharmaceuticals since the beginning of time. This implies concentrating on a wide range of biological activities to illuminate potential secondary metabolite modes of action. Materials and Methods: The study was carried out using literature review using keywords such as Ajos sacha, Adenocalymma alliaceum Miers through search engine Google Scholar, Science direct, PubMed, and Elsevier. Result and Discussion: The Ajos Sacha has many active metabolites and sulfur compounds similar to garlic. Furthermore, due to biologically abundant active secondary metabolites such as polyphenol, flavonoid, tannic acid, and sulfur compounds, the plant has been documented for numerous biological activities such as antibacterial activity, anti-inflammatory activity, antifungal activity, anticancer activity, anthelmintic activity, larvicidal activity, and hypocholesterolemic activity. Due to the presence of sulfur in garlic creeper, the plant has shown inhibition of tubulin polymerization or impedes the G2-M phase via Cdc25C signaling. In addition, the Ajos Sacha flower extract inhibits phosphatidylserine translocation, and caspase-3 activation causes apoptosis. The Ajos Sacha was also documented due to its inhibition characteristic on tubulin polymerization or blocking the G2-M phase via Cdc25C signaling. Conclusion: This review presents the role of Ajos Sacha on biological activities, including free radical scavenging property. Henceforth, this plant can be utilized in clinical screening too.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3217
      Issue No: Vol. 16, No. 1 (2022)
       
  • Anti-termite and antimicrobial efficacy of latexes from certain plant
           families

    • Authors: Dr. Ravi Kant Upadhyay
      Abstract: The present article explains the effect of plant latex and its formulations on termite control. Latex is natural plant
      polymer secreted by highly specialized cells known as laticifers. It is a milky white thick complex mixture of
      proteins, alkaloids, starch, sugars, oils, tannins, resins, and gums. Both latex and its components show multiple
      deleterious effects such as toxic, antifeedant, and repellent activities. These effectively inhibit growth and
      reproductive behavior in number of insect species. Latex components delay egg maturation, development, and
      inhibit gonad development in termites. Latex constituents display contact and systemic action and primarily used
      as poison baits to control soil termite. Latex-based combinatorial anti-termite formulations could be used in spray
      for termite control. The usage is safer than synthetic chemicals and will minimize the risk of poisoning of food
      chain, soil, and aqueous environment. This review article suggests the use of slow release of latex components
      inside soil when applied as poison baits for control of field termites.
      PubDate: 2022-04-22
      DOI: 10.22377/ijgp.v16i1.3218
      Issue No: Vol. 16, No. 1 (2022)
       
 
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