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- Are insulin sensitizers the new strategy to treat Type 1 diabetes' A
long‐acting dual amylin and calcitonin receptor agonist improves
insulin‐mediated glycaemic control and controls body weight-
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Authors:
Simone Anna Melander; Anna Thorsø Larsen,
Morten Asser Karsdal,
Kim Henriksen
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1829-1842, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16329
Issue No: Vol. 181, No. 12 (2024)
- Pharmacology of erenumab in human isolated coronary and meningeal
arteries: Additional effect of gepants on top of a maximum effect of
erenumab-
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Authors:
Tessa de Vries; Eloísa Rubio‐Beltrán,
Antoon van den Bogaerdt,
Ruben Dammers,
A. H. Jan Danser,
Josefin Snellman,
Jeanine Bussiere,
Antoinette MaassenVanDenBrink
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1720-1733, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16322
Issue No: Vol. 181, No. 12 (2024)
- Complement tunes glutamate release and supports synaptic impairments in an
animal model of multiple sclerosis-
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Authors:
Guendalina Olivero; Alice Taddeucci,
Giulia Vallarino,
Hanna Trebesova,
Alessandra Roggeri,
Maria Cristina Gagliani,
Katia Cortese,
Massimo Grilli,
Anna Pittaluga
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1812-1828, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16328
Issue No: Vol. 181, No. 12 (2024)
- Issue Information
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Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1693-1694, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16127
Issue No: Vol. 181, No. 12 (2024)
- The cytoplasmic sensor, the AIM2 inflammasome: A precise therapeutic
target in vascular and metabolic diseases-
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Authors:
Jiuguo Lin; Jiaojiao Wang,
Jian Fang,
Meihang Li,
Suowen Xu,
Peter J. Little,
Dongmei Zhang,
Zhiping Liu
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1695-1719, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16355
Issue No: Vol. 181, No. 12 (2024)
- Radiprodil, a selective GluN2B negative allosteric modulator, rescues
audiogenic seizures in mice carrying the GluN2A(N615S) mutation-
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Authors:
Ilaria Bertocchi; Lorenzo Cifarelli,
Alessandra Oberto,
Carola Eugenia Eva,
Rolf Sprengel,
Naheed Rohman Mirza,
Pierandrea Muglia
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1886-1894, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16361
Issue No: Vol. 181, No. 12 (2024)
- Andrographolide regulates H3 histone lactylation by interfering with p300
to alleviate aortic valve calcification-
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Authors:
Chunli Wang; Shunshun Wang,
Zijun Wang,
Juanjuan Han,
Nan Jiang,
Linghang Qu,
Kang Xu
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1843-1856, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16332
Issue No: Vol. 181, No. 12 (2024)
- An orally available Cav2.2 calcium channel inhibitor for the
treatment of neuropathic pain-
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Authors:
Janine Kutzsche; Gustavo A. Guzman,
Antje Willuweit,
Olaf Kletke,
Esther Wollert,
Ian Gering,
Dagmar Jürgens,
Jörg Breitkreutz,
Holger Stark,
Annette G. Beck‐Sickinger,
Nikolaj Klöcker,
Patricia Hidalgo,
Dieter Willbold
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1734-1756, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16309
Issue No: Vol. 181, No. 12 (2024)
- Voltage tunes mGlu5 receptor function, impacting synaptic transmission
-
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Authors:
Marin Boutonnet; Camille Carpena,
Nathalie Bouquier,
Yan Chastagnier,
Joan Font‐Ingles,
Enora Moutin,
Ludovic Tricoire,
Jean Chemin,
Julie Perroy
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1793-1811, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16317
Issue No: Vol. 181, No. 12 (2024)
- Ginsenosides retard atherogenesis via remodelling host–microbiome
metabolic homeostasis-
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Authors:
Yun Wang; Jiawei Wu,
Yu Hong,
Jiaying Zhu,
Youcai Zhang,
Jun Zhang,
Chujie Ding,
Yuan Che,
Guangji Wang,
Aiqin Jiang,
Haiping Hao,
Lijuan Cao
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1768-1792, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16320
Issue No: Vol. 181, No. 12 (2024)
- Why classical receptor theory, which ignores allostery, can effectively
measure the strength of an allosteric effect as agonist's efficacy-
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Authors:
H. Ongun Onaran; Tommaso Costa
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1757-1767, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16327
Issue No: Vol. 181, No. 12 (2024)
- Holotoxin A1 from Apostichopus japonicus inhibited oropharyngeal and
intra‐abdominal candidiasis by inducing oxidative damage in Candida
albicans-
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Authors:
Min Liao; Xuekui Xia,
Qingzhou Meng,
Chengguang Zhu,
Binyou Liao,
Jiannan Wang,
Lichen Gou,
Xuedong Zhou,
Wenpeng Yuan,
Lei Cheng,
Biao Ren
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1857-1873, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16333
Issue No: Vol. 181, No. 12 (2024)
- Characterisation of cotadutide's dual GLP‐1/glucagon receptor agonistic
effects on glycaemic control using an in vivo human glucose regulation
quantitative systems pharmacology model-
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Authors:
Rolien Bosch; Marcella Petrone,
Rosalin Arends,
Paolo Vicini,
Eric J. G. Sijbrands,
Sven Hoefman,
Nelleke Snelder
Abstract: British Journal of Pharmacology, Volume 181, Issue 12, Page 1874-1885, June 2024.
PubDate: 2024-05-09T01:12:31-07:00
DOI: 10.1111/bph.16336
Issue No: Vol. 181, No. 12 (2024)
- Butyrate acts as a positive allosteric modulator of the 5‐HT transporter
to decrease availability of 5‐HT in the ileum-
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Authors:
Jieling Cai; Jamie Cheung,
Samson W. M. Cheung,
Karie T. C. Chin,
Ricky W. K. Leung,
Ronald S. T. Lam,
Rakesh Sharma,
Jensen H. C. Yiu,
Connie W. Woo
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1654-1670, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16305
Issue No: Vol. 181, No. 11 (2024)
- Issue Information
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Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1551-1552, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16126
Issue No: Vol. 181, No. 11 (2024)
- Correction to Improved survival and reversal of endothelial dysfunction by
the 21‐aminosteroid, U‐74389G in splanchnic ischaemia‐reperfusion
injury in the rat-
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Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1690-1690, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16384
Issue No: Vol. 181, No. 11 (2024)
- Correction to “Contribution of intercellular adhesion molecule 1
(ICAM‐1) to the pathogenesis of splanchnic artery occlusion shock in the
rat”-
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Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1691-1691, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16385
Issue No: Vol. 181, No. 11 (2024)
- Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in
review-
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Authors:
Andreas Papapetropoulos; Stavros Topouzis,
Steve P. H. Alexander,
Miriam Cortese‐Krott,
Dave A. Kendall,
Kirill A. Martemyanov,
Claudio Mauro,
Nithyanandan Nagercoil,
Reynold A. Panettieri Jr,
Hemal H. Patel,
Rainer Schulz,
Barbara Stefanska,
Gary J. Stephens,
Mauro M. Teixeira,
Nathalie Vergnolle,
Xin Wang,
Péter Ferdinandy
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1553-1575, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16337
Issue No: Vol. 181, No. 11 (2024)
- Piezo1‐mediated regulation of smooth muscle cell volume in response to
enhanced extracellular matrix rigidity-
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Authors:
Robert T. Johnson; Reesha Solanki,
Finn Wostear,
Sultan Ahmed,
James C. K. Taylor,
Jasmine Rees,
Geraad Abel,
James McColl,
Helle F. Jørgensen,
Chris J. Morris,
Stefan Bidula,
Derek T. Warren
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1576-1595, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16294
Issue No: Vol. 181, No. 11 (2024)
- Extracellular ATP inhibits excitatory synaptic input on parvalbumin
positive interneurons and attenuates gamma oscillations via P2X4 receptors
-
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Authors:
Florian Wildner; Tim S. Neuhäusel,
Alexander Klemz,
Richard Kovács,
Lauriane Ulmann,
Jörg R. P. Geiger,
Zoltan Gerevich
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1635-1653, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16298
Issue No: Vol. 181, No. 11 (2024)
- Oat β‐glucan repairs the epidermal barrier by upregulating the levels
of epidermal differentiation, cell–cell junctions and lipids via
Dectin‐1-
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Authors:
Rongrong Jing; Mengli Fu,
Yuhan Huang,
Kaini Zhang,
Jiabin Ye,
Fanghua Gong,
Al‐bashari Jihea Ali Naji Nasser,
Xiashun Xu,
Jiali Xiao,
Guangdong Yu,
Shisheng Lin,
Wengang Zhao,
Nuo Xu,
Xiaokun Li,
Zhiming Li,
Shuang Gao
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1596-1613, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16306
Issue No: Vol. 181, No. 11 (2024)
- Resveratrol, a novel inhibitor of fatty acid binding protein 5, inhibits
cervical cancer metastasis by suppressing fatty acid transport into
nucleus and downstream pathways-
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Authors:
Xiao Chen; Jing Tian,
Chunyuan Zhao,
Yanhui Wu,
Jiahuang Li,
Zehan Ji,
Danchen Lian,
Zhibo Jia,
Xingyu Chen,
Zixin Zhou,
Bo Zhu,
Zichun Hua
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1614-1634, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16308
Issue No: Vol. 181, No. 11 (2024)
- Ayahuasca‐enhanced extinction of fear behaviour: Role of infralimbic
cortex 5‐HT2A and 5‐HT1A receptors-
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Authors:
Isabel Werle; Laura M. M. Nascimento,
Aymee L. A. dos Santos,
Luciane A. Soares,
Rafael G. dos Santos,
Jaime E. C. Hallak,
Leandro J. Bertoglio
Abstract: British Journal of Pharmacology, Volume 181, Issue 11, Page 1671-1689, June 2024.
PubDate: 2024-05-02T01:40:18-07:00
DOI: 10.1111/bph.16315
Issue No: Vol. 181, No. 11 (2024)
- Non‐coding RNAs to treat vascular smooth muscle cell dysfunction
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Authors:
Simon D. Brown; Eftychia Klimi,
Wilfried A. M. Bakker,
Abdelaziz Beqqali,
Andrew H. Baker
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T09:58:34-07:00
DOI: 10.1111/bph.16409
- A novel ryanodine receptor 2 inhibitor, M201‐A, enhances natriuresis,
renal function and lusi‐inotropic actions: Preclinical and phase I study
-
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Authors:
Noboru Kaneko; Christopher M. Loughrey,
Godfrey Smith,
Ryuko Matsuda,
Tomoko Hasunuma,
Patric B. Mark,
Masashi Toda,
Makoto Shinozaki,
Naoyuki Otani,
Scott Kayley,
Ana Da Silva Costa,
Tamara P. Martin,
Sara Dobi,
Priyanka Saxena,
Ken Shimamoto,
Tetsuya Ishikawa,
Ryuichi Kambayashi,
Alexandra Riddell,
Elspeth B. Elliott,
Charlotte S. McCarroll,
Toshiya Sakai,
Yamano Mitsuhisa,
Sayuri Hirano,
Takeshi Kitai,
Kengo Kusano,
Yuko Inoue,
Masahiko Nakamura,
Migaku Kikuchi,
Shigeru Toyoda,
Isao Taguchi,
Toshihiko Fujiwara,
Atsushi Sugiyama,
Yuji Kumagai,
Kunio Iwata
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T08:18:16-07:00
DOI: 10.1111/bph.16379
- Extent of foetal exposure to maternal elexacaftor/tezacaftor/ivacaftor
during pregnancy-
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Authors:
Danni Li; Martin Donnelley,
David Parsons,
Mark D. Habgood,
Elena K. Schneider‐Futschik
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T05:00:11-07:00
DOI: 10.1111/bph.16417
- The neuropharmacological properties of α‐pyrrolidinobutiothiophenone, a
new synthetic cathinone, in rodents; role of the dopaminergic system-
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Authors:
Oc‐Hee Kim; Kyung Oh Jeon,
Gihyeon Kim,
Choon‐Gon Jang,
Seong Shoon Yoon,
Eun Young Jang
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T04:40:05-07:00
DOI: 10.1111/bph.16422
- Schwann cell TRPA1 elicits reserpine‐induced fibromyalgia pain in
mice-
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Authors:
Evelyne Silva Brum; Maria Fernanda Pessano Fialho,
Daniel Souza Monteiro de Araújo,
Lorenzo Landini,
Matilde Marini,
Mustafa Titiz,
Bruna Luiza Kuhn,
Clarissa Piccinin Frizzo,
Pedro Henrique Silva Araújo,
Rafaela Mano Guimarães,
Thiago Mattar Cunha,
Cássia Regina Silva,
Gabriela Trevisan,
Pierangelo Geppetti,
Romina Nassini,
Francesco De Logu,
Sara Marchesan Oliveira
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T04:10:00-07:00
DOI: 10.1111/bph.16413
- Differing contributions of the gut microbiota to the blood pressure
lowering effects induced by first‐line antihypertensive drugs-
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Authors:
Cristina González‐Correa; Javier Moleón,
Sofía Miñano,
Iñaki Robles‐Vera,
Marta Toral,
Antonio Manuel Barranco,
Natividad Martín‐Morales,
Francisco O'Valle,
Eduardo Guerra‐Hernández,
Manuel Sánchez,
Manuel Gómez‐Guzmán,
Rosario Jiménez,
Miguel Romero,
Juan Duarte
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-21T02:33:39-07:00
DOI: 10.1111/bph.16410
- Identification and characterisation of functional Kir6.1‐containing
ATP‐sensitive potassium channels in the cardiac ventricular sarcolemmal
membrane-
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Authors:
Sean Brennan; Shen Chen,
Samir Makwana,
Simona Esposito,
Lauren R. McGuinness,
Abrar I. M. Alnaimi,
Mark W. Sims,
Manish Patel,
Qadeer Aziz,
Leona Ojake,
James A. Roberts,
Parveen Sharma,
David Lodwick,
Andrew Tinker,
Richard Barrett‐Jolley,
Caroline Dart,
Richard D. Rainbow
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-19T05:34:42-07:00
DOI: 10.1111/bph.16390
- Discovery platforms for RNA therapeutics
-
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Authors:
Giulio Ciucci; Luca Braga,
Serena Zacchigna
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-17T09:18:57-07:00
DOI: 10.1111/bph.16424
- Direct neuronal protection by the protease‐activated receptor PAR4
antagonist ML354 after experimental stroke in mice-
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Authors:
Michael Fleischer; Rebecca D. Szepanowski,
Valeria Pesara,
Julia Sophie Bihorac,
Beatrice Oehler,
Dobromir Dobrev,
Christoph Kleinschnitz,
Anke C. Fender
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-17T09:18:52-07:00
DOI: 10.1111/bph.16415
- Ginsenoside Rh4 prevents endothelial dysfunction as a novel AMPK activator
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Authors:
Jiawei Zhang; Weiqiang Lv,
Xuyun Liu,
Zhenyu Sun,
Mengqi Zeng,
Jiahao Kang,
Qi Zhang,
Fuying Liu,
Shaozhou Ma,
Jiacan Su,
Ke Cao,
Jiankang Liu
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-16T10:38:39-07:00
DOI: 10.1111/bph.16403
- The mutated cytoplasmic fragile X mental retardation 1
(FMR1)‐interacting protein 2 (CYFIP2 S968F) regulates
cocaine‐induced reward behaviour and plasticity in the nucleus accumbens
-
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Authors:
Young‐Jung Kim; Kyungin Kim,
Youyoung Lee,
Hee‐Won Min,
Yong‐Hyun Ko,
Bo‐Ram Lee,
Kwang‐Hyun Hur,
Seon‐Kyung Kim,
Seok‐Yong Lee,
Choon‐Gon Jang
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-15T11:18:20-07:00
DOI: 10.1111/bph.16427
- Montelukast improves disease outcome in SOD1G93A female mice by
counteracting oligodendrocyte dysfunction and aberrant glial reactivity-
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Stefano Raffaele; Nhung Nguyen,
Marco Milanese,
Francesca C. Mannella,
Marta Boccazzi,
Giulia Frumento,
Giambattista Bonanno,
Maria P. Abbracchio,
Tiziana Bonifacino,
Marta Fumagalli
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-15T10:54:37-07:00
DOI: 10.1111/bph.16408
- Anti‐chitinase‐3‐like 1 antibody attenuated atopic dermatitis‐like
skin inflammation through inhibition of STAT3‐dependent CXCL8 expression
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Ji Eun Yu; Seong Hee Jeon,
Min Ji Kim,
Dae Hwan Kim,
Ja Keun Koo,
Tae Hun Kim,
Bongcheol Kim,
Ji Yong Yoon,
Young‐soo Lim,
So Ra Park,
In Jun Yeo,
Jaesuk Yun,
Dong Ju Son,
Sang‐Bae Han,
Yong Sun Lee,
Jin Tae Hong
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-14T12:00:00-07:00
DOI: 10.1111/bph.16365
- Topical application of a P2X2/P2X3 purine receptor inhibitor suppresses
the bitter taste of medicines and other taste qualities-
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Linda J. Flammer; Hillary Ellis,
Natasha Rivers,
Lauren Caronia,
Misgana Y. Ghidewon,
Carol M. Christensen,
Peihua Jiang,
Paul A. S. Breslin,
Michael G. Tordoff
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-14T09:39:33-07:00
DOI: 10.1111/bph.16411
- TRPA1 up‐regulation mediates oxidative stress in a pulpitis model in
vitro-
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Árpád Kunka; Erika Lisztes,
Judit Bohács,
Márk Racskó,
Balázs Kelemen,
Gabriella Kovalecz,
Etelka D. Tóth,
Csaba Hegedűs,
Kinga Bágyi,
Rita Marincsák,
Balázs István Tóth
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-14T07:55:21-07:00
DOI: 10.1111/bph.16386
- ApTOLL: A new therapeutic aptamer for cytoprotection and (re)myelination
after multiple sclerosis-
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Beatriz Fernández‐Gómez; Miguel A. Marchena,
David Piñeiro,
Paula Gómez‐Martín,
Estefanía Sánchez,
Yolanda Laó,
Gloria Valencia,
Sonia Nocera,
Rocío Benítez‐Fernández,
Ana M. Castaño‐León,
Alfonso Lagares,
Macarena Hernández‐Jiménez,
Fernando de Castro
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-14T01:39:59-07:00
DOI: 10.1111/bph.16399
- Nicorandil mitigates arsenic trioxide‐induced lung injury via modulating
vital signalling pathways SIRT1/PGC‐1α/TFAM, JAK1/STAT3, and
miRNA‐132 expression-
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Basel A. Abdel‐Wahab; Dalia Zafaar,
Mohammed Shafiuddin Habeeb,
Ehab A. M. El‐Shoura
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-13T11:33:54-07:00
DOI: 10.1111/bph.16414
- The ion channel TRPM8 is a direct target of the immunosuppressant
rapamycin in primary sensory neurons-
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José Miguel Arcas; Khalid Oudaha,
Alejandro González,
Jorge Fernández‐Trillo,
Francisco Andrés Peralta,
Júlia Castro‐Marsal,
Seyma Poyraz,
Francisco Taberner,
Salvador Sala,
Elvira de la Peña,
Ana Gomis,
Félix Viana
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-13T11:29:38-07:00
DOI: 10.1111/bph.16402
- Differential G protein activation by the long and short isoforms of the
dopamine D2 receptor-
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David Reiner‐Link; Jakob Sture Madsen,
David E. Gloriam,
Hans Bräuner‐Osborne,
Alexander S. Hauser
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-09T11:54:19-07:00
DOI: 10.1111/bph.16388
- Recent advances in neuroinflammation prevention and therapy: the role of
natural products and underlying mechanisms based on molecular targets-
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Mei‐Mei Zhao; Jun‐Yu Duan,
Yue Shen,
Yang Liu,
Ke‐Wu Zeng
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-09T02:44:06-07:00
DOI: 10.1111/bph.16404
- Targeting noncoding RNAs to treat atherosclerosis
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Miron Sopić; Sandra Vladimirov,
Jelena Munjas,
Tijana Mitić,
Ignacio Fernando Hall,
Amela Jusic,
Dusan Ruzic,
Yvan Devaux, On behalf of AtheroNET COST Action CA21153 (https://atheronet.eu/)
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-08T10:15:08-07:00
DOI: 10.1111/bph.16412
- Neuroprotective amyloid β N‐terminal peptides differentially alter
human α7‐ and α7β2‐nicotinic acetylcholine (nACh) receptor
single‐channel properties-
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Catherine F. Roberts; Yiwei Cao,
Wonpil Im,
Robert A. Nichols,
Ronald J. Lukas,
Andrew A. George
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-08T08:14:26-07:00
DOI: 10.1111/bph.16381
- Naringenin relieves paclitaxel‐induced pain by suppressing calcitonin
gene‐related peptide signalling and enhances the anti‐tumour action of
paclitaxel-
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Authors:
Chen Pan; Yuhao Xu,
Zongsheng Jiang,
Chengjiang Fan,
Zhexi Chi,
Yu Zhang,
Mengmeng Miao,
Yuxuan Ren,
Ziyi Wu,
Linbin Xu,
Changqing Mei,
Qingge Chen,
Yang Xi,
Xiaowei Chen
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-07T11:39:01-07:00
DOI: 10.1111/bph.16397
- ST‐2560, a selective inhibitor of the NaV1.7 sodium channel, affects
nocifensive and cardiovascular reflexes in non‐human primates-
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John V. Mulcahy; Jacob T. Beckley,
Sheri D. Klas,
Debra A. Odink,
Anton Delwig,
Hassan Pajouhesh,
Dennis Monteleone,
Xiang Zhou,
Justin Du Bois,
David C. Yeomans,
George Luu,
John C. Hunter
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-07T11:04:39-07:00
DOI: 10.1111/bph.16398
- Commentary on: Activation of Nrf2 signalling pathway by tectoridin
protects against ferroptosis in particulate matter‐induced lung injury-
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Wenfu Cao; Xinrui Guo,
Xinyu Li,
Dapeng Chen
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-06T08:08:08-07:00
DOI: 10.1111/bph.16418
- Pharmacological inhibition of STING reduces neuroinflammation‐mediated
damage post‐traumatic brain injury-
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Authors:
Amelia L. Fryer; Amar Abdullah,
Frank Mobilio,
Andrew Jobling,
Zachery Moore,
Michael de Veer,
Gang Zheng,
Bruce X. Wong,
Juliet M. Taylor,
Peter J. Crack
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-06T07:40:35-07:00
DOI: 10.1111/bph.16347
- HIF‐1α and adaptor protein LIM and senescent cell antigen‐like
domains protein 1 axis promotes tubulointerstitial fibrosis by interacting
with vimentin in angiotensin II‐induced hypertension-
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Authors:
Wei‐Jie Ni; Zuo‐Lin Li,
Xian‐Li Wen,
Jia‐Ling Ji,
Hong Liu,
Qing Yin,
Liang‐Yun‐Zi Jiang,
Yi‐Lin Zhang,
Yi Wen,
Tao‐Tao Tang,
Wei Jiang,
Lin‐Li Lv,
Wei‐Hua Gan,
Bi‐Cheng Liu,
Bin Wang
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-03T12:30:24-07:00
DOI: 10.1111/bph.16358
- Nicotine inhalant via E‐cigarette facilitates sensorimotor function
recovery by upregulating neuronal BDNF–TrkB signalling in traumatic
brain injury-
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Authors:
Dongsheng Wang; Xiaojing Li,
Wenxi Li,
Tiffany Duong,
Hongxia Wang,
Natalia Kleschevnikova,
Hemal H. Patel,
Ellen Breen,
Susan Powell,
Shanshan Wang,
Brian P. Head
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-05-02T08:24:47-07:00
DOI: 10.1111/bph.16395
- Activation of M4 muscarinic receptors in the striatum reduces tic‐like
behaviours in two distinct murine models of Tourette syndrome-
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Roberto Cadeddu; Giulia Braccagni,
Caterina Branca,
Easton R. van Luik,
Christopher Pittenger,
Morten Skøtt Thomsen,
Marco Bortolato
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-30T08:21:25-07:00
DOI: 10.1111/bph.16392
- Implications and hidden toxicity of cardiometabolic syndrome and
early‐stage heart failure in carfilzomib‐induced cardiotoxicity-
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Panagiotis Efentakis; Aimilia Varela,
Sofia Lamprou,
Eleni‐Dimitra Papanagnou,
Michail Chatzistefanou,
Andriana Christodoulou,
Constantinos H. Davos,
Maria Gavriatopoulou,
Ioannis Trougakos,
Meletios Athanasios Dimopoulos,
Evangelos Terpos,
Ioanna Andreadou
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T11:19:20-07:00
DOI: 10.1111/bph.16391
- Autocrine activation of P2X7 receptors mediates catecholamine secretion in
chromaffin cells-
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Authors:
María Constanza Maldifassi; María José Guerra‐Fernández,
Daniela Ponce,
Samuel Alfonso‐Bueno,
Jaime Maripillán,
Alex H. Vielma,
Ximena Báez‐Matus,
Fernando D. Marengo,
Claudio Acuña‐Castillo,
Juan C. Sáez,
Agustín D. Martínez,
Ana M. Cárdenas
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T11:05:11-07:00
DOI: 10.1111/bph.16371
- A long‐acting FGF21 attenuates metabolic dysfunction‐associated
steatohepatitis‐related fibrosis by modulating NR4A1‐mediated Ly6C
phenotypic switch in macrophages-
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Authors:
Yue Ji; Yiliang Duan,
Yuanyuan Li,
Qingzhou Lu,
Dingkang Liu,
Yifan Yang,
Ruilong Chang,
Jing Tian,
Wenbing Yao,
Jun Yin,
Xiangdong Gao
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T06:44:09-07:00
DOI: 10.1111/bph.16378
- AdipoRon promotes amyloid‐β clearance through enhancing autophagy via
nuclear GAPDH‐induced sirtuin 1 activation in Alzheimer's disease-
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Authors:
Fengjiao Sun; Jiangong Wang,
Lingbin Meng,
Zhenyu Zhou,
Yong Xu,
Meizi Yang,
Yixin Li,
Tianrui Jiang,
Bin Liu,
Haijing Yan
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T06:34:10-07:00
DOI: 10.1111/bph.16400
- Daidzein ameliorates nonmotor symptoms of manganese‐induced Parkinsonism
in zebrafish model: Behavioural and biochemical approach-
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Authors:
Balasubramanian Haridevamuthu; Gokul Sudhakaran,
Raman Pachaiappan,
Muthu Kumaradoss Kathiravan,
Krishnan Manikandan,
Mikhlid H. Almutairi,
Bader O. Almutairi,
Selvaraj Arokiyaraj,
Jesu Arockiaraj
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T06:24:15-07:00
DOI: 10.1111/bph.16382
- ZnPP‐laden nanoparticles improve glucose homeostasis and chronic
inflammation during obesity-
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Authors:
Wanbao Yang; Meenakshi Arora,
Hye Won Han,
Wen Jiang,
Da Mi Kim,
Weiqi Ai,
Quan Pan,
M. N. V. Ravi Kumar,
Wesley A. Brashear,
Yuxiang Sun,
Shaodong Guo
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T05:54:22-07:00
DOI: 10.1111/bph.16356
- Targeting IL‐11 to reduce fibrocyte circulation and lung accumulation in
animal models of pulmonary hypertension‐associated lung fibrosis-
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Authors:
Javier Milara; Inés Roger,
Paula Montero,
Enrique Artigues,
Juan Escrivá,
Raquel Del Río,
Julio Cortijo
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-28T04:30:00-07:00
DOI: 10.1111/bph.16393
- The oxytocin antagonist cligosiban reduces human prostate contractility:
Implications for the treatment of benign prostatic hyperplasia-
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Authors:
Beatrix Bester; Kristina Koslowa,
Ann‐Catherine Gronau,
Andrea Mietens,
Cameron Nowell,
Michael R. Whittaker,
Adrian Pilatz,
Florian Wagenlehner,
Betty Exintaris,
Ralf Middendorff
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-27T12:00:00-07:00
DOI: 10.1111/bph.16369
- Non‐linear blood–brain barrier transport and dosing strategies
influence receptor occupancy ratios of morphine and its metabolites in
pain matrix-
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Authors:
Divakar Budda; Berfin Gülave,
J. G. Coen van Hasselt,
Elizabeth C. M. de Lange
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-25T03:53:37-07:00
DOI: 10.1111/bph.16394
- A triple cysteine motif as major determinant of the modulation of neuronal
KV7 channels by the paracetamol metabolite N‐acetyl‐p‐benzo quinone
imine-
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Sutirtha Ray; Jan‐Luca Stampf,
Oliver Kudlacek,
Jae‐Won Yang,
Klaus W. Schicker,
Yvonne Graf,
Thomas Losgott,
Stefan Boehm,
Isabella Salzer
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-24T04:25:26-07:00
DOI: 10.1111/bph.16380
- Signalling switches maintain intercellular communication in the vascular
endothelium-
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Charlotte Buckley; Matthew D. Lee,
Xun Zhang,
Calum Wilson,
John G. McCarron
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-23T12:54:27-07:00
DOI: 10.1111/bph.16366
- Early erythroferrone levels can predict the long‐term haemoglobin
responses to erythropoiesis‐stimulating agents-
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Authors:
Peng Xu; Raymond S. M. Wong,
Xiaoyu Yan
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-23T04:18:41-07:00
DOI: 10.1111/bph.16396
- Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation
of G protein activity in post‐mortem human brain-
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Authors:
Itziar Muneta‐Arrate; Patricia Miranda‐Azpiazu,
Igor Horrillo,
Rebeca Diez‐Alarcia,
J. Javier Meana
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-21T09:13:06-07:00
DOI: 10.1111/bph.16368
- White adipose tissue, a novel antirheumatic target: Clues from its
secretory capability and adipectomy‐based therapy-
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Authors:
Peng Ye; Qi‐Hai Wang,
Wen‐Ye Kong,
Chun‐Sheng Liu,
Dan‐Dan Wang,
Opeyemi Joshua Olatunji,
Yan Li,
Jian Zuo
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-21T09:01:13-07:00
DOI: 10.1111/bph.16360
- Transient receptor potential ankyrin 1 channel modulates the
abuse‐related mechanisms of methamphetamine through interaction with
dopamine transporter-
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Authors:
Kwang‐Hyun Hur; Youyoung Lee,
Audrey Lynn Donio,
Seon‐Kyung Kim,
Bo‐Ram Lee,
Jee‐Yeon Seo,
Dooti Kundu,
Kyeong‐Man Kim,
Stephen J. Kohut,
Seok‐Yong Lee,
Choon‐Gon Jang
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-21T08:55:19-07:00
DOI: 10.1111/bph.16370
- Hydroxymethylglutaryl‐CoA reductase activity is essential for
mitochondrial β‐oxidation of fatty acids to prevent lethal accumulation
of long‐chain acylcarnitines in the mouse liver-
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Authors:
Edgars Liepinsh; Liga Zvejniece,
Laura Clemensson,
Melita Ozola,
Edijs Vavers,
Helena Cirule,
Stanislava Korzh,
Sandra Skuja,
Valerija Groma,
Monta Briviba,
Solveiga Grinberga,
Wen Liu,
Paweł Olszewski,
Mélissa Gentreau,
Robert Fredriksson,
Maija Dambrova,
Helgi B. Schiöth
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-19T11:44:52-07:00
DOI: 10.1111/bph.16363
- Chymotrypsin activity signals to intestinal epithelium by
protease‐activated receptor‐dependent mechanisms-
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Authors:
Simon Guignard; Mahmoud Saifeddine,
Koichiro Mihara,
Majid Motahhary,
Magali Savignac,
Laura Guiraud,
David Sagnat,
Mireille Sebbag,
Sokchea Khou,
Corinne Rolland,
Anissa Edir,
Barbara Bournet,
Louis Buscail,
Etienne Buscail,
Laurent Alric,
Caroline Camare,
Mouna Ambli,
Nathalie Vergnolle,
Morley D. Hollenberg,
Céline Deraison,
Chrystelle Bonnart
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-18T06:59:37-07:00
DOI: 10.1111/bph.16341
- Graph‐based algorithms to dissect long‐distance water‐mediated
H‐bond networks for conformational couplings in GPCRs-
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Authors:
Éva Bertalan; Matthew Joseph Rodrigues,
Gebhard F. X. Schertler,
Ana‐Nicoleta Bondar
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-18T03:49:53-07:00
DOI: 10.1111/bph.16387
- Postnatal hypofunction of N‐methyl‐D‐aspartate receptors alters
perforant path synaptic plasticity and filtering and impairs dentate
gyrus‐mediated spatial discrimination-
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Luis A. Márquez; Carolina López Rubalcava,
Emilio J. Galván
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-17T06:05:30-07:00
DOI: 10.1111/bph.16375
- Calcium‐sensing receptor regulates Kv7 channels via Gi/o protein
signalling and modulates excitability of human induced pluripotent stem
cell‐derived nociceptive‐like neurons-
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Authors:
Nontawat Chuinsiri; Nannapat Siraboriphantakul,
Luke Kendall,
Polina Yarova,
Christopher J. Nile,
Bing Song,
Ilona Obara,
Justin Durham,
Vsevolod Telezhkin
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-16T06:34:45-07:00
DOI: 10.1111/bph.16349
- Synergism between remdesivir and ribavirin leads to SARS‐CoV‐2
extinction in cell culture-
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Authors:
Carlos García‐Crespo; Ana Isabel de Ávila,
Isabel Gallego,
María Eugenia Soria,
Antoni Durán‐Pastor,
Pilar Somovilla,
Brenda Martínez‐González,
Javier Muñoz‐Flores,
Pablo Mínguez,
Llanos Salar‐Vidal,
Mario Esteban‐Muñoz,
Elizabeth Cañar‐Camacho,
Cristina Ferrer‐Orta,
Sonia Zuñiga,
Isabel Sola,
Luis Enjuanes,
Jaime Esteban,
Ricardo Fernández‐Roblas,
Ignacio Gadea,
Jordi Gómez,
Nuria Verdaguer,
Esteban Domingo,
Celia Perales
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-14T06:35:51-07:00
DOI: 10.1111/bph.16344
- Pharmacology of PACAP and VIP receptors in the spinal cord highlights the
importance of the PAC1 receptor-
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Authors:
Zoe Tasma; Tayla A. Rees,
Song Guo,
Sheryl Tan,
Simon J. O'Carroll,
Richard L. M. Faull,
Maurice A. Curtis,
Sarah L. Christensen,
Debbie L. Hay,
Christopher S. Walker
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-14T05:09:19-07:00
DOI: 10.1111/bph.16376
- Role of protein kinase A and A kinase anchoring proteins in buffering and
compartmentation of cAMP signalling in human airway smooth muscle cells-
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Authors:
Rinzhin T. Sherpa; Karni S. Moshal,
Shailesh R. Agarwal,
Rennolds S. Ostrom,
Robert D. Harvey
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-12T10:34:41-07:00
DOI: 10.1111/bph.16357
- Differential contributions of G protein‐ or arrestin subtype‐mediated
signalling underlie urocortin 3‐induced somatostatin secretion in
pancreatic δ cells-
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Authors:
Kai‐Yu Wang; Ming‐Xin Gao,
Hai‐Bo Qi,
Wen‐tao An,
Jing‐Yu Lin,
Shang‐Lei Ning,
Fan Yang,
Peng Xiao,
Jie Cheng,
Wei Pan,
Qiu‐xia Cheng,
Jin Wang,
Le Fang,
Jin‐Peng Sun,
Xiao Yu
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-12T10:24:52-07:00
DOI: 10.1111/bph.16351
- A novel reuptake inhibitor, IP2015, induces erection by increasing central
dopamine and peripheral nitric oxide release-
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Authors:
Simon Comerma‐Steffensen; Attila Kun,
Judit Prat‐Duran,
Susie Mogensen,
Elif Alan Albayrak,
Rafael Fais,
Gordon Munro,
Dan Peters,
Ulf Simonsen
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-11T04:54:53-07:00
DOI: 10.1111/bph.16362
- A natural inhibitor of diapophytoene desaturase attenuates
methicillin‐resistant Staphylococcus aureus (MRSA) pathogenicity and
overcomes drug‐resistance-
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Authors:
Baoqing Han; Hongsu Wang,
Xiaodi Niu
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-11T04:45:03-07:00
DOI: 10.1111/bph.16377
- BRD2‐specific inhibitor, BBC0403, inhibits the progression of
-
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Authors:
Hyemi Lee; Jiho Nam,
Hahyeong Jang,
Young‐Sik Park,
Min‐Hee Son,
In‐Hyun Lee,
Seong‐il Eyun,
Jae‐Hyun Yang,
Jimin Jeon,
Siyoung Yang
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-10T08:53:44-07:00
DOI: 10.1111/bph.16359
- Bardoxolone methyl prevents metabolic dysfunction‐associated
steatohepatitis by inhibiting macrophage infiltration-
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Authors:
Kazuhiro Onuma; Kenji Watanabe,
Keishiro Isayama,
Sayaka Ogi,
Yasunori Tokunaga,
Yoichi Mizukami
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-10T05:10:13-07:00
DOI: 10.1111/bph.16374
- LncRNA XIST modulates miR‐328‐3p ectopic expression in lung injury
induced by tobacco‐specific lung carcinogen NNK both in vitro and in
vivo-
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Authors:
Bingxin Li; Xuezheng Li,
Zhe Jiang,
Di Zhou,
Yuan Feng,
Gang Chen,
Ning Li
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-08T07:44:16-07:00
DOI: 10.1111/bph.16373
- The insulin‐like growth factor binding protein–microfibrillar
associated protein–sterol regulatory element binding protein axis
regulates fibroblast–myofibroblast transition and cardiac fibrosis-
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Authors:
Qianwen Zhao; Tinghui Shao,
Shan Huang,
Junjie Zhang,
Genjie Zong,
Lili Zhuo,
Yong Xu,
Wenxuan Hong
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-08T01:24:10-07:00
DOI: 10.1111/bph.16314
- Immunomodulation by juglone alleviates acute graft‐versus‐host disease
without compromising the graft‐versus‐leukaemia activity in mice-
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Authors:
Dievya Gohil; Khushboo A. Gandhi,
Saurabh Kumar Gupta,
Poonam Gera,
Subhash Yadav,
Raghavendra Patwardhan,
Rahul Checker,
Deepak Sharma,
Navin Khattry,
Santosh Sandur,
Vikram Gota
Abstract: British Journal of Pharmacology, EarlyView.
PubDate: 2024-04-07T06:25:01-07:00
DOI: 10.1111/bph.16350
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