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- Chrysin-loaded calixarene-cyclodextrin ternary drug delivery system
inhibits TGF-β and galectin-1 mediated pathways in diabetic liver fibrosis-
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Abstract: Publication date: November 2024Source: Biochemical Pharmacology, Volume 229Author(s): Cornel Balta, Hildegard Herman, Alina Ciceu, Caterina Claudia Lepre, Bianca Mladin, Marcel Rosu, Daniela Oatis, Marina Russo, Victor Eduard Peteu, Mihaela Gherghiceanu, Ferenc Fenyvesi, Coralia Cotoraci, Maria Consiglia Trotta, Michele D’Amico, Anca Hermenean
- Deregulation of lactate permeability using a small-molecule transporter
(Lactrans-1) disturbs intracellular pH and triggers cancer cell death-
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Abstract: Publication date: November 2024Source: Biochemical Pharmacology, Volume 229Author(s): Alain Arias-Betancur, Pere Fontova, Daniel Alonso-Carrillo, Israel Carreira-Barral, Janneke Duis, María García-Valverde, Vanessa Soto-Cerrato, Roberto Quesada, Ricardo Pérez-Tomás
- Hyperglycemia-driven signaling bridges between diabetes and cancer
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Abstract: Publication date: November 2024Source: Biochemical Pharmacology, Volume 229Author(s): Somayyeh Ghareghomi, Payam Arghavani, Majid Mahdavi, Ali Khatibi, Custodia García-Jiménez, Ali A. Moosavi-Movahedi
- Alamandine, a protective component of the renin-angiotensin system,
reduces cellular proliferation and interleukin-6 secretion in human macrophages through MasR–MrgDR heteromerization-
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Abstract: Publication date: Available online 10 August 2024Source: Biochemical PharmacologyAuthor(s): Natalia L. Rukavina Mikusic, Mauro G. Silva, Fernando A. Erra Díaz, Angélica M. Pineda, Fátima Ferragut, Karina A. Gómez, Luciana Mazzitelli, Daniel H. Gonzalez Maglio, Myriam Nuñez, Robson A.S. Santos, Hernán E. Grecco, Mariela M. Gironacci
- The ‘ABC’ of split-nanoluciferase HIF heterodimerization bioassays:
Applications, benefits & considerations-
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Abstract: Publication date: Available online 10 August 2024Source: Biochemical PharmacologyAuthor(s): Liesl K. Janssens, Christophe P. Stove
- Reduced FNDC5-AMPK signaling in diabetic atrium increases the
susceptibility of atrial fibrillation by impairing mitochondrial dynamics and activating NLRP3 inflammasome-
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Abstract: Publication date: Available online 10 August 2024Source: Biochemical PharmacologyAuthor(s): Shan Meng, Xin Chen, Jikai Zhao, Xinyi Huang, Yuting Huang, Tao Huang, Zijun Zhou, Wenpu Ren, Tao Hong, Jinfeng Duan, Liming Yu, Huishan Wang
- Trimetazidine attenuates Ischemia/Reperfusion-Induced myocardial
ferroptosis by modulating the Sirt3/Nrf2-GSH system and reducing Oxidative/Nitrative stress-
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Abstract: Publication date: Available online 10 August 2024Source: Biochemical PharmacologyAuthor(s): Mingyue Tan, Yunfei Yin, Weixiang Chen, Jun Zhang, Yifeng Jin, Yue Zhang, Lei Zhang, Tingbo Jiang, Bin Jiang, Hongxia Li
- Endothelial Birc3 promotes renal fibrosis through modulating Drp1-mediated
mitochondrial fission via MAPK/PI3K/Akt pathway-
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Abstract: Publication date: Available online 10 August 2024Source: Biochemical PharmacologyAuthor(s): Shuai Chen, Qingqing He, Huaiyu Yang, Hongxing Huang
- CDK9 inhibitors for the treatment of solid tumors
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Abstract: Publication date: Available online 8 August 2024Source: Biochemical PharmacologyAuthor(s): Christiana Mo, Ning Wei, Terence Li, Muzaffer Ahmed Bhat, Mahshid Mohammadi, Chaoyuan Kuang
- Peptide GLP-1 receptor agonists: From injection to oral delivery
strategies-
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Abstract: Publication date: Available online 8 August 2024Source: Biochemical PharmacologyAuthor(s): Zhiqiang Ke, Qianqian Ma, Xiaonan Ye, Yanlin Wang, Yan Jin, Xinyuan Zhao, Zhengding Su
- Novel curcumin derivatives N17 exert anti-cancer effects through the
CSNK1G3/AKT axis in triple-negative breast cancer-
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Abstract: Publication date: Available online 8 August 2024Source: Biochemical PharmacologyAuthor(s): Ziyou Huai, Zijian Li, Wei Xue, Shujing Li, Yinjiu Huang, Xin Cao, Qinjun Wei, Yuanyuan Wang
- USP24 promotes hepatocellular carcinoma tumorigenesis through
deubiquitinating and stabilizing TRAF2-
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Abstract: Publication date: Available online 8 August 2024Source: Biochemical PharmacologyAuthor(s): Nana Zhou, Chaoqin Guo, Xiangyu Li, Linglan Tu, Jingyang Du, Qiyi Qian, Juejiashan Li, Dongsheng Huang, Qiuran Xu, Xiaoliang Zheng
- Synergistic effects of resveratrol and enzyme replacement therapy in the
Mucopolysaccharidosis type I-
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Abstract: Publication date: Available online 5 August 2024Source: Biochemical PharmacologyAuthor(s): Estera Rintz, Maja Ziemian, Barbara Kobus, Lidia Gaffke, Karolina Pierzynowska, Grzegorz Wegrzyn
- Unachieved antiviral strategies with acyclic nucleoside phosphonates:
Dedicated to the memory of dr. Salvatore “Sam” Joseph Enna-
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Abstract: Publication date: Available online 21 July 2024Source: Biochemical PharmacologyAuthor(s): Erik De Clercq, Guangdi Li, Yun Zhang, Jie Huang, Li Tan
- Unravelling metabolic factors impacting iNKT cell biology in obesity
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Abstract: Publication date: Available online 17 July 2024Source: Biochemical PharmacologyAuthor(s): Chloé Wilkin, Jacques Piette, Sylvie Legrand-Poels
- Molecular targets of PXR-dependent ethanol-induced hepatotoxicity in
female mice-
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Abstract: Publication date: Available online 8 July 2024Source: Biochemical PharmacologyAuthor(s): Sora Choi, Malvin Ofosu-Boateng, Sarah Kim, Daniel O. Nnamani, Mia Mah’moud, Prince Neequaye, Lidya H. Gebreyesus, Elizabeth Twum, Frank J. Gonzalez, Julia Yue Cui, Maxwell A. Gyamfi
- Molecular glues as potential GPCR therapeutics
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Abstract: Publication date: Available online 28 June 2024Source: Biochemical PharmacologyAuthor(s): Bryan L. Roth, Brian E. Krumm
- Passing the torch: The ascendance of the glutamatergic synapse in the
pathophysiology of schizophrenia-
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Abstract: Publication date: Available online 19 June 2024Source: Biochemical PharmacologyAuthor(s): Joseph T. Coyle
- A historical perspective and recent advances on the evolution of the
relationship between acute and chronic pain and cardiovascular disease-
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Abstract: Publication date: Available online 8 June 2024Source: Biochemical PharmacologyAuthor(s): James E. Barrett, Andrew R. Kohut
- Adrenalectomy exacerbates stress-induced impairment in fear
discrimination: A causal role for kynurenic acid'-
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Abstract: Publication date: Available online 7 June 2024Source: Biochemical PharmacologyAuthor(s): Alex D. Klausing, Tsutomu Fukuwatari, Nicole DeAngeli, David J. Bucci, Robert Schwarcz
- Reprogramming of urea cycle in cancer: Mechanism, regulation and
prospective therapeutic scopes-
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Abstract: Publication date: Available online 28 May 2024Source: Biochemical PharmacologyAuthor(s): Noyel Ghosh, Sushweta Mahalanobish, Parames C. Sil
- SHU9119 and MBP10 are biased ligands at the human melanocortin-4 receptor
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Abstract: Publication date: Available online 28 May 2024Source: Biochemical PharmacologyAuthor(s): Han-Chuan Dai, Ren-Lei Ji, Ya-Xiong Tao
- Pharmacological and molecular mechanisms of miRNA-based therapies for
targeting cardiovascular dysfunction-
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Abstract: Publication date: Available online 25 May 2024Source: Biochemical PharmacologyAuthor(s): Alejandro Gonzalez-Candia, Esteban G Figueroa, Bernardo J Krause
- Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in
keratinocytes-
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Abstract: Publication date: Available online 24 May 2024Source: Biochemical PharmacologyAuthor(s): Styliani Iliaki, Marja Kreike, Natalia Ferreras Moreno, Femke De Meyer, Aigerim Aidarova, Harald Braun, Claude Libert, Inna S. Afonina, Rudi Beyaert
- The excitatory-inhibitory balance as a target for the development of novel
drugs to treat schizophrenia-
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Abstract: Publication date: Available online 21 May 2024Source: Biochemical PharmacologyAuthor(s): Daniela L. Uliana, Joao Roberto F. Lisboa, Felipe V. Gomes, Anthony A. Grace
- AMPA receptors play an important role in the biological consequences of
spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit-
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Abstract: Publication date: Available online 18 May 2024Source: Biochemical PharmacologyAuthor(s): Jeffrey M. Witkin, Daniel P. Radin, Sabhya Rana, David D. Fuller, Anna F. Fusco, Julie C. Demers, Prajwal Pradeep Thakre, Jodi L. Smith, Arnold Lippa, Rok Cerne
- Induction of mitochondrial toxicity by non-steroidal anti-inflammatory
drugs (NSAIDs): The ultimate trade-off governing the therapeutic merits and demerits of these wonder drugs-
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Abstract: Publication date: Available online 13 May 2024Source: Biochemical PharmacologyAuthor(s): Somnath Mazumder, Samik Bindu, Subhashis Debsharma, Uday Bandyopadhyay
- Hiding in plain sight: Do recruited dendritic cells surround amyloid
plaques in Alzheimer’s disease'-
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Abstract: Publication date: Available online 3 May 2024Source: Biochemical PharmacologyAuthor(s): Robert B. Nelson, Kenneth N. Rose, Frank S. Menniti, Stevin H. Zorn
- Mechanotransduction and the extracellular matrix: Key drivers of lung
pathologies and drug responsiveness-
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Abstract: Publication date: Available online 3 May 2024Source: Biochemical PharmacologyAuthor(s): Janette K Burgess, Reinoud Gosens
- Targeting cyclooxygenase-2 for chemoprevention of inflammation-associated
intestinal carcinogenesis: An update-
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Abstract: Publication date: Available online 3 May 2024Source: Biochemical PharmacologyAuthor(s): Kyung-Soo Chun, Eun-Hee Kim, Do-Hee Kim, Na-Young Song, Wonki Kim, Hye-Kyung Na, Young-Joon Surh
- ARL13B promotes cell cycle through the sonic hedgehog signaling pathway to
alleviate nerve damage during cerebral ischemia/reperfusion in rats-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Lu Jiang, Shaonan Yang, Ling Deng, Jingjing Luo, Xiaoling Zhang, Sha Chen, Zhi Dong
- Multivalent CXCR4-targeting nanobody formats differently affect affinity,
receptor clustering, and antagonism-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Stephanie M. Anbuhl, Xavier Dervillez, Saskia Neubacher, Angela I. Schriek, Vladimir Bobkov, Steven W. de Taeye, Martyna Szpakowska, Marco Siderius, Tom N. Grossmann, Andy Chevigné, Martine J. Smit, Raimond Heukers
- The ester-containing prodrug NT-0796 enhances delivery of the NLRP3
inflammasome inhibitor NDT-19795 to monocytic cells expressing carboxylesterase-1-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): John R. Doedens, Christine Diamond, David Harrison, Mark G. Bock, Nicholas Clarke, Alan P. Watt, Christopher A. Gabel
- Furanodienone induces apoptosis via regulating the
PRDX1/MAPKs/p53/caspases signaling axis through NOX4-derived mitochondrial ROS in colorectal cancer cells-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Ying Jiang, Yanli Li, Yuzhu Wang, Xiaoyu Li
- CC chemokine receptor 2 is allosterically modulated by sodium ions and
amiloride derivatives through a distinct sodium ion binding site-
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Abstract: Publication date: Available online 5 August 2024Source: Biochemical PharmacologyAuthor(s): Lisa S. den Hollander, Annelien J.M. Zweemer, Olivier J.M. Béquignon, Dora M. Hammerl, Bente T.M. Bleijs, Margo Veenhuizen, Wernard J.F. Lantsheer, Bobby Chau, Gerard J.P. van Westen, Adriaan P. IJzerman, Laura H. Heitman
- ABC transporters involved in respiratory and cholestatic diseases: From
rare to very rare monogenic diseases-
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Abstract: Publication date: Available online 5 August 2024Source: Biochemical PharmacologyAuthor(s): Mounia Lakli, Marion Onnée, Thomas Carrez, Frédéric Becq, Thomas Falguières, Pascale Fanen
- Citrulline activates adenosine receptors: New insight into metabolic
pathways interaction-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Anatoly Soloviev, Vadym Kozlowsky, Vadym Sydorenko, Irina Ivanova, Dariia Samofalova, Vladimir Fetyukhin
- Spider and scorpion knottins targeting voltage-gated sodium ion channels
in pain signaling-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Xiting Wang, Huan Luo, Xiaozhen Peng, Jinjun Chen
- Targeting the Wnt/β-catenin signal pathway for the treatment of
gastrointestinal cancer: Potential for advancement-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Xizhi Jin, Sijie Wang, Lihua Luo, Fangjie Yan, Qiaojun He
- Dysregulated lncSNHG12 suppresses the invasion and migration of
trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Zehao Wang, Sisi Yan, Shichong Liao, Yan Zhang, Shujuan Wu, Mengqi Zhou, Wenyi Jin, Yi Zhang, Xinyu Qi, Chaogang Yang, Jing Yang, Jinli Ding
- BCL6 confers resistance to HDAC inhibitors in DLBCL
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Gao Fan, Yuchen Zhang, Qi Li, Rong Rong, Si Chen, Lexin He, Bingzong Li, Wenzhuo Zhuang
- A novel selective FAK inhibitor E2 inhibits ovarian cancer metastasis and
growth by inducing cytotoxic autophagy-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Zhanzhan Feng, Wei Wei, Shirui Wang, Xiao Li, Lifeng Zhao, Guoquan Wan, Rong Hu, Luoting Yu
- Juglone suppresses vasculogenic mimicry in glioma through inhibition of
HuR-mediated VEGF-A expression-
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Abstract: Publication date: Available online 3 August 2024Source: Biochemical PharmacologyAuthor(s): Chunying Luo, Guzhou Chen, Ruixiang Li, Shoujiao Peng, Pei Zhang, Feiyun Wang, Shaopeng Yu, Yuying Zhu, Jiange Zhang
- Circ_0002722-induced regulation of YAP promotes platinum resistance in
oral squamous cell carcinoma: Implications for verteporfin therapy-
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Abstract: Publication date: Available online 2 August 2024Source: Biochemical PharmacologyAuthor(s): Hsiao-Chi Tsai, Ming-Hsui Tsai, Chun-Hung Hua, Chun-Wei Huang, Chien-Chi Lu, Kwei-Jing Chen, Michael Yuan-Chien Chen, Ming-Yu Lien, Chih-Hsin Tang
- Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation
partially regulates aerobic activities in human hepatocytes and HepG2 cells-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Kristof De Vos, Adamantios Mavrogiannis, Justina Clarinda Wolters, Susan Schlenner, Keimpe Wierda, Álvaro Cortés Calabuig, Reena Chinnaraj, Vera Dermesrobian, Yeghig Armoudjian, Maarten Jacquemyn, Nikky Corthout, Dirk Daelemans, Pieter Annaert
- Impact of the redox-active MnTnHex-2-PyP5+ and cisplatin on the metabolome
of non-small cell lung cancer cells-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Rita B. Soares, Joana Pinto, Filipa Amaro, Rita Manguinhas, Nuno Gil, Rafael Rosell, Ines Batinic-Haberle, Ana S. Fernandes, Nuno G. Oliveira, Paula Guedes de Pinho
- Feasibility and efficacy of pemafibrate for prevention of maternal
high-fat intake-induced glucose metabolic dysfunction in offspring-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Matome Imai, Shuang Liu, Akiko Yano, Yasuyuki Suzuki, Masaki Mogi, Takashi Sugiyama
- Inhibition of KIAA1429/HK1 axis enhances the sensitivity of liver cancer
cells to sorafenib by regulating the Warburg effect-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Dong Liu, Meihua Shan, Rong Zeng, Meng He, Xufang Dai, Lu Lu, Mingzhen Yang, Haiyan He, Yang Zhang, Li Xiang, An Chen, Liangbo Sun, Fengtian He, Jiqin Lian
- Activating the iNOS regulatory pathway by arginine deprivation targets
energy metabolism to induce autophagy-dependent apoptosis against spinal echinococcosis-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Haimiti Abudouaini, Xuefang Zhang, Yi Dai, Yibin Meng, Qing Lu, Qian Ren, Haohao Sun, Yibo Ma, Baorong He, Sibo Wang
- Human β-defensins: The multi-functional natural peptide
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Abstract: Publication date: Available online 25 July 2024Source: Biochemical PharmacologyAuthor(s): Haile Zhao, Shuli Zhao, Simeng Wang, Ying Liu
- Inhibition of PLA2G4A attenuated valproic acid- induced lysosomal membrane
permeabilization and restored impaired autophagic flux: Implications for hepatotoxicity-
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Abstract: Publication date: Available online 25 July 2024Source: Biochemical PharmacologyAuthor(s): Ming-Lu Wang, Yu-Jia Zhang, Da-Long He, Tong Li, Ming-Ming Zhao, Li-mei Zhao
- Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity
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Abstract: Publication date: Available online 24 July 2024Source: Biochemical PharmacologyAuthor(s): Ying Zhang, Ying Pu, Yuanyuan Deng, Bo Liu, Ke Chen, Yiling Xu, Weihong Tan, Huixia Liu, Jinwei Wang
- Preliminary study on the mechanism of SAHA in the treatment of refractory
epilepsy induced by GABRG2(F343L) mutation-
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Abstract: Publication date: Available online 23 July 2024Source: Biochemical PharmacologyAuthor(s): Jie Wang, Wenwen Wu, Jiali Wan, Longwu Zhan, Yuhan Chen, Feng Yun, Yuhua Ji, Guihai Suo, Yuqin Zheng, Dingding Shen, Qi Zhang
- Corrigendum to “20-Deoxyingenol alleviates intervertebral disc
degeneration by activating TFEB in nucleus pulposus cells”[Biochem. Pharmacol. 218 (2023) 115865]-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Yu Chen, Chenyu Wu, Xiaoying Zhao, Hongye Tan, Chenchao Li, Yuxin Deng, Ximiao Chen, Yaosen Wu, Naifeng Tian, Xiaolei Zhang, Yifei Zhou, Liaojun Sun
- Untargeted metabolomics analysis of serum and urine unveils the protective
effect of cilastatin on altered metabolic pathways during cisplatin-induced acute kidney injury-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Estefanía Moreno-Gordaliza, M. Ángeles González-Nicolás, Alberto Lázaro, Coral Barbas, M. Milagros Gómez-Gómez, Ángeles López-Gonzálvez
- Lamivudine protects mice from gastric ulcer by activating PGK1 to suppress
ferroptosis-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Xinrui Meng, Jingjing Liu, Jia Kang, Menghan Wang, Zhanghui Guan, Dong Tian, Xinping Chen
- Reg2 treatment is protective but the induced Reg2 autoantibody is
destructive to the islets in NOD mice-
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Abstract: Publication date: Available online 20 July 2024Source: Biochemical PharmacologyAuthor(s): Yi-Han Zhou, Lu-Ting Yu, Xiao-Nan Wang, You-Jie Li, Ke-Yi Xu, Xin Li, Chun-Cheng Pu, Fei-Lu Xie, Bing-Bing Xie, Yan Gao, Chen Luo
- Hepatoprotective potential of alpha-lipoic acid against gliclazide-induced
liver injury in high-glucose-exposed human liver cells and experimental type 2 diabetic rats-
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Abstract: Publication date: Available online 20 July 2024Source: Biochemical PharmacologyAuthor(s): George J. Dugbartey, Stephen Atule, Karl K. Alornyo, Ismaila Adams
- Molecular mechanism of co-stimulatory domains in promoting CAR-T cell
anti-tumor efficacy-
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Abstract: Publication date: Available online 18 July 2024Source: Biochemical PharmacologyAuthor(s): Wanxin Zhao, Yizhou Yao, Qihong Li, Ying Xue, Xiaoge Gao, Xiangye Liu, Qing Zhang, Junnian Zheng, Shishuo Sun
- Engineering a long acting, non-biased relaxin agonist using
Protein-in-Protein technology-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Irina U. Agoulnik, Elena M. Kaftanovskaya, Courtney Myhr, Ross A.D. Bathgate, Martina Kocan, Yingjie Peng, Ronald M. Lindsay, Peter S. DiStefano, Alexander I. Agoulnik
- Renal protection after hemorrhagic shock in rats: Possible involvement of
SUMOylation-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Filipe Rodolfo Moreira Borges Oliveira, Ericks Sousa Soares, Hanna Pillmann Ramos, Gisela Lättig-Tünnemann, Christoph Harms, Helena Cimarosti, Regina Sordi
- Dipsacoside B ameliorates cognitive impairment in sepsis-associated
encephalopathy by reducing Th17 cell infiltration and neuroinflammation-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Sha Peng, Taoli Sun, Dongmei Yang, Hongqing Zhao, Limei Lin, Bohou Xia, Minjie Li, Meihong Piao, Zhe Shi, Qinhui Tuo
- TFAP2A is involved in neuropathic pain by regulating Grin1 expression in
glial cells of the dorsal root ganglion-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Bao-Tong Yuan, Meng-Na Li, Lin-Peng Zhu, Meng-Lin Xu, Jun Gu, Yong-Jing Gao, Ling-Jie Ma
- Novel functions of o-cymen-5-ol nanoemulsion in reversing colistin
resistance in multidrug-resistant Klebsiella pneumoniae infections-
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Abstract: Publication date: September 2024Source: Biochemical Pharmacology, Volume 227Author(s): Qiushuang Sheng, Xiao Wang, Zhaoyan Hou, Bin Liu, Mingquan Jiang, Mingyue Ren, Jingchao Fu, Miao He, Jingchen Zhang, Yue Xiang, Qingbo Zhang, Lanying Zhou, Yanhong Deng, Xue Shen
- Key links in the physiological regulation of the immune system and disease
induction: T cell receptor -CD3 complex-
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Abstract: Publication date: Available online 17 July 2024Source: Biochemical PharmacologyAuthor(s): Danyan Liu, Xiaoxi Hu, Zhaoying Chen, Wei Wei, Yujing Wu
- Maladaptive regeneration and metabolic dysfunction associated steatotic
liver disease: Common mechanisms and potential therapeutic targets-
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Abstract: Publication date: Available online 16 July 2024Source: Biochemical PharmacologyAuthor(s): Dandan Wu, Stan F.J. van de Graaf
- Laurocapram, a transdermal enhancer, boosts cephalosporin’s
antibacterial activity against Methicillin-resistant Staphylococcus aureus -
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Abstract: Publication date: Available online 28 June 2024Source: Biochemical PharmacologyAuthor(s): Nan Wang, Wei Li, Hui Yu, Wenlin Huang, Yarui Qiao, Qi Wang, Yunfei Wei, Xuming Deng, Jianfeng Wang, Minhe Cui, Peng Zhang, Yonglin Zhou
- Aspirin alleviates fibronectin-induced preeclampsia phenotypes in a mouse
model and reverses fibronectin-mediated trophoblast invasiveness under hypoxia by regulating ciliogenesis and Akt and MAPK signaling-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Pei-Yin Tsai, Chih-I Lee, Hoi-Lam Tam, Mei-Tsz Su
- The YY1-CPT1C signaling axis modulates the proliferation and metabolism of
pancreatic tumor cells under hypoxia-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Yanying Zhou, Yixin Chen, Pengfei Zhao, Tu Xian, Yue Gao, Shicheng Fan, Jian-Hong Fang, Min Huang, Huichang Bi
- Vitamin D and systemic lupus erythematosus: Causality and association with
disease activity and therapeutics-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Ling-Jun Ho, Chien-Hsiang Wu, Shue-Fen Luo, Jenn-Haung Lai
- Voltage dependence of M2 muscarinic receptor antagonists and allosteric
modulators-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Shimrit Hazan, Merav Tauber, Yair Ben Chaim
- The deubiquitinase OTUD1 deubiquitinates TIPE2 and plays a protective role
in sepsis-induced lung injury by targeting TAK1-mediated MAPK and NF-κB signaling-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Tingqian Ming, Huifan Liu, Min Yuan, Jingyuan Tian, Qing Fang, Yuping Liu, Qian Kong, Qian Wang, Xuemin Song, Zhongyuan Xia, Xiaojing Wu
- Selective STAT3 inhibitor STX-0119 alleviates osteoarthritis progression
by modulating the STAT3/PPARγ signaling pathway-
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Abstract: Publication date: Available online 10 July 2024Source: Biochemical PharmacologyAuthor(s): Xuanyuan Lu, Yangjun Xu, Xinhuo Li, Jing Wang, Lei Wang, Xujun Hu, Honghui Fan, Fei Pang, Xin Li, Xiaoyu Pan, Wei He, Jianlei Li, Zhangsheng Dai
- Relaxin suppresses atrial fibrillation, reverses fibrosis and reduces
inflammation in aged hearts-
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Abstract: Publication date: Available online 3 July 2024Source: Biochemical PharmacologyAuthor(s): Guillermo Romero, Brian Martin, Beth Gabris, Guy Salama
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