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- Metabolic bioactivation of antidepressants: advance and underlying
hepatotoxicity-
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Authors: Saleh M. Khalil Kevin R. MacKenzie Mirjana Maletic-Savatic Feng Li a Department of Pathology & Immunology; Center for Drug Discovery, Baylor College of Medicine, Houston, TX, USAb NMR Dan Duncan Neurological Research Institute, TX Children’s Hospital, Houston, TX, USA
Pages: 97 - 126
Abstract: Volume 56, Issue 2, February - May 2024, Page 97-126
.
Citation: Drug Metabolism Reviews
PubDate: 2024-02-20T08:26:11Z
DOI: 10.1080/03602532.2024.2313967
Issue No: Vol. 56, No. 2 (2024)
- Favipiravir, remdesivir, and lopinavir: metabolites, degradation products
and their analytical methods-
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Authors: Mir Saleh Hoseininezhad-Namin Elaheh Rahimpour Abolghasem Jouyban a Pharmaceutical Analysis Research Center; Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Pages: 127 - 144
Abstract: Volume 56, Issue 2, February - May 2024, Page 127-144
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Citation: Drug Metabolism Reviews
PubDate: 2024-03-06T11:36:38Z
DOI: 10.1080/03602532.2024.2326415
Issue No: Vol. 56, No. 2 (2024)
- Investigating the association between CYP2J2 inhibitors and QT
prolongation: a literature review-
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Authors: Alexandra M. Wiley Jade Yang Rivcka Madhani Abhinav Nath Rheem A. Totah Department of Medicinal Chemistry; University of WA School of Pharmacy, Seattle, WA, USA
Pages: 145 - 163
Abstract: Volume 56, Issue 2, February - May 2024, Page 145-163
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Citation: Drug Metabolism Reviews
PubDate: 2024-03-20T11:19:10Z
DOI: 10.1080/03602532.2024.2329928
Issue No: Vol. 56, No. 2 (2024)
- Effects of cannabidiol and Δ9-tetrahydrocannabinol on cytochrome P450
enzymes: a systematic review-
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Authors: Sarah Ann Smith Gia Han Le Kayla M. Teopiz Angela T.H. Kwan Taeho Greg Rhee Roger C. Ho Jie Wu Bing Cao Felicia Ceban Roger S. McIntyre a Brain; Personality (Ministry of Education), Southwest University, Chongqing, P. R. Chinak Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canadal Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Pages: 164 - 174
Abstract: Volume 56, Issue 2, February - May 2024, Page 164-174
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Citation: Drug Metabolism Reviews
PubDate: 2024-04-30T07:32:33Z
DOI: 10.1080/03602532.2024.2346767
Issue No: Vol. 56, No. 2 (2024)
- Insights into pharmacogenetics, drug-gene interactions, and drug-drug-gene
interactions-
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Authors: Laura E. Russell Katrina G. Claw Kaja M. Aagaard Sarah M. Glass Kuheli Dasgupta F. Leah Nez Alex Haimbaugh Benjamin J. Maldonato Jaydeep Yadav a Drug Metabolism; Bioanalytics, Merck & Co., Inc, Boston, MA, USA
Pages: 1 - 19
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-08-18T06:06:17Z
DOI: 10.1080/03602532.2024.2385928
- Mechanisms of intestinal pharmacokinetic natural product-drug interactions
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Authors: Victoria O. Oyanna John D. Clarke Department of Pharmaceutical Sciences; WA State University, Spokane, Washington, USA
Pages: 1 - 17
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-08-12T09:23:20Z
DOI: 10.1080/03602532.2024.2386597
- Hepatotoxicity of epidermal growth factor receptor - tyrosine kinase
inhibitors (EGFR-TKIs)-
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Authors: Lulin Zhu Xinxin Yang Shanshan Wu Rong Dong Youyou Yan Nengming Lin Bo Zhang Biqin Tan a Department of Pharmacy; Key Laboratory of Clinical CancerPharmacology andToxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, Chinab School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Chinac Westlake Laboratory of Life Sciences Biomedicine of Zhejiang Province, Hangzhou, Chinad Cancer Center, Zhejiang University, Hangzhou, China
Pages: 1 - 16
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-08-09T01:12:03Z
DOI: 10.1080/03602532.2024.2388203
- Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro
methodologies, regulatory guidance, and translation to the clinic-
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Authors: Jaydeep Yadav Benjamin J. Maldonato Joseph M. Roesner Ana G. Vergara Erickson M. Paragas Theresa Aliwarga Sara Humphreys a Department of Pharmacokinetics; Dynamics, Metabolism &Bioanalytics (PDMB), Merck & Co., Inc., Boston, MA, USAb Department of Nonclinical Development Drug Metabolism Department, Amgen Research, South San Francisco, CA, USA
Pages: 1 - 33
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-07-26T12:53:10Z
DOI: 10.1080/03602532.2024.2381021
- Bioactivation and reactivity research advances – 2023 year in review
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Authors: Shuai Wang Upendra A. Argikar Maria Chatzopoulou Sungjoon Cho Rachel D. Crouch Deepika Dhaware Ting-Jia Gu Carley J. S. Heck Kevin M. Johnson Amit S. Kalgutkar Joyce Liu Bin Ma Grover P. Miller Jessica A. Rowley Herana Kamal Seneviratne Donglu Zhang S. Cyrus Khojasteh a Department of Drug Metabolism; Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA
Pages: 1 - 38
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-07-17T11:27:45Z
DOI: 10.1080/03602532.2024.2376023
- Biotransformation research advances – 2023 year in review
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Authors: S. Cyrus Khojasteh Upendra A. Argikar Maria Chatzopoulou Lionel Cheruzel Sungjoon Cho Deepika Dhaware Kevin M. Johnson Amit S. Kalgutkar Joyce Liu Bin Ma Hlaing Maw Jessica A. Rowley Herana Kamal Seneviratne Shuai Wang a Department of Drug Metabolism; Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA
Pages: 1 - 33
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-07-11T10:12:20Z
DOI: 10.1080/03602532.2024.2370330
- Metabolism of new drug modalities research advances – 2023 year in
review-
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Authors: Bin Ma Upendra A Argikar Lionel Cheruzel Sungjoon Cho Simon Hauri Kevin M Johnson Joyce Liu Simone Schadt Shuai Wang S. Cyrus Khojasteh a Department of Drug Metabolism; Pharmacokinetics, Inotiv, Maryland Heights, MO, USA
Pages: 1 - 24
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-07-05T12:53:09Z
DOI: 10.1080/03602532.2024.2370331
- Transporter-mediated drug-drug interactions: regulatory guidelines, in
vitro and in vivo methodologies and translation, special populations, and
the blood-brain barrier-
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Authors: Laura E. Russell Jaydeep Yadav Benjamin J. Maldonato Huan-Chieh Chien Ling Zou Ana G. Vergara Erick G. Villavicencio a Department of Quantitative; Translational, Functional Genomics, Merck & Co., Inc, Rahway, NJ, USA
Pages: 1 - 28
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-07-05T12:48:58Z
DOI: 10.1080/03602532.2024.2364591
- Ocular drug-metabolizing enzymes: focus on esterases
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Authors: Anam Hammid Paavo Honkakoski School of Pharmacy; University of Eastern Finland, Kuopio, Finland
Pages: 1 - 15
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-06-19T12:18:23Z
DOI: 10.1080/03602532.2024.2368247
- Advances in drug resistance of osteosarcoma caused by pregnane X receptor
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Authors: Kunhong Mao Can Liu Zhongwen Tang Zhouzhou Rao Jie Wen a Key Laboratory of Translational Cancer Stem Cell Research; Department of Physiology, Hunan Normal University School of Medicine, Changsha, Chinab Department of Anatomy, Hunan Normal University school of Medicine, Changsha, Chinac Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China
Pages: 1 - 14
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-06-14T04:50:41Z
DOI: 10.1080/03602532.2024.2366948
- Assessing and mitigating pH-mediated DDI risks in drug development –
formulation approaches and clinical considerations-
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Authors: Di Wu Jiaying Liu Erickson M. Paragas Jaydeep Yadav Theresa Aliwarga Tycho Heimbach M. Sebastian Escotet-Espinoza a Pharmaceutical Sciences & Clinical Supply; Merck & Co., Inc, Rahway, NJ, USAb Pharmacokinetics Drug Metabolism, Merck & Co., Inc, Boston, MA, USA
Pages: 1 - 20
Abstract: .
Citation: Drug Metabolism Reviews
PubDate: 2024-05-03T12:44:53Z
DOI: 10.1080/03602532.2024.2345632
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