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- Synergistic induction of IL-6 production in human bronchial epithelial
cells in vitro by nickel nanoparticles and lipopolysaccharide is mediated
by STAT3 and C/EBPβ-
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Abstract: Publication date: Available online 25 May 2022Source: Toxicology in VitroAuthor(s): Dorothy J. You, Ho Young Lee, Alexia J. Taylor-Just, James C. Bonner
- Evaluation of mitochondrial oxidative toxicity in mammalian cardiomyocytes
by determining the highly reproducible and reliable increase in
mitochondrial superoxides after exposure to therapeutic drugs-
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Abstract: Publication date: Available online 23 May 2022Source: Toxicology in VitroAuthor(s): Dohee Ahn, Cho-Won Kim, Ryeo-Eun Go, Kyung-Chul Choi
- Transcriptome sequencing of 3,3′,4,4′,5-Pentachlorobiphenyl
(PCB126)-treated human preadipocytes demonstrates progressive changes in
pathways associated with inflammation and diabetes.-
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Abstract: Publication date: Available online 23 May 2022Source: Toxicology in VitroAuthor(s): Francoise A. Gourronc, Brynn K. Helm, Larry W. Robertson, Michael S. Chimenti, Hans Joachim-Lehmler, James A. Ankrum, Aloysius J. Klingelhutz
- Pracaxi oil affects xenobiotic metabolisms, cellular proliferation, and
oxidative stress without cytotogenotoxic effects in HepG2/C3A cells-
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Abstract: Publication date: Available online 20 May 2022Source: Toxicology in VitroAuthor(s): Camila Lehnhardt Pires, Thalita Alves Zanetti, Mario Sergio Mantovani, Isabel O'Neill de Mascarenhas Gaivão, Fábio Ferreira Perazzo, Paulo Cesar Pires Rosa, Edson Luis Maistro
- Frankenstein's followers. Maintenance of human cells outside the body.
Issue 1-
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Abstract: Publication date: August 2022Source: Toxicology in Vitro, Volume 82Author(s): Walter Pfaller, Paul Jennings
- Silibinin inhibits ethanol- or acetaldehyde-induced ferroptosis in liver
cell lines-
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Abstract: Publication date: Available online 18 May 2022Source: Toxicology in VitroAuthor(s): Xiao-Yu Song, Peng-Cheng Liu, Wei-Wei Liu, Jia Zhou, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima
- Study of the metabolic stability profiles of perampanel, rufinamide and
stiripentol and prediction of drug interactions using HepaRG cells as an
in vitro human model-
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Abstract: Publication date: Available online 18 May 2022Source: Toxicology in VitroAuthor(s): Sara Meirinho, Márcio Rodrigues, Ana Fortuna, Amílcar Falcão, Gilberto Alves
- Donor-to-donor variability of a human three-dimensional bronchial
epithelial model: A case study of cigarette smoke exposure-
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Abstract: Publication date: Available online 18 May 2022Source: Toxicology in VitroAuthor(s): Sakura Mori, Kanae Ishimori, Kazushi Matsumura, Shinkichi Ishikawa, Shigeaki Ito
- In-house performance assessment of 3D QobuR-Reconstructed Human
Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard-
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Abstract: Publication date: Available online 17 May 2022Source: Toxicology in VitroAuthor(s): Manuel Chacón, Natalia Vázquez, Mairobi Persinal-Medina, Sergio Alonso-Alonso, Ignacio Alcalde, Jesús Merayo-Lloves, Álvaro Meana
- Paclitaxel is evidence to reduce growing ovarian follicle growth in mice
model study-
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Abstract: Publication date: Available online 15 May 2022Source: Toxicology in VitroAuthor(s): Mila Maidarti, Wataru Tarumi, Seido Takae, Budi Wiweko, Nao Suzuki
- Transdermal permeation of inorganic cerium salts in intact human skin
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Abstract: Publication date: August 2022Source: Toxicology in Vitro, Volume 82Author(s): Greta Camilla Magnano, Giovanna Marussi, Francesca Larese Filon, Matteo Crosera, Massimo Bovenzi, Gianpiero Adami
- Inhibition of epithelial SHH signaling exerts a dual protective effect
against inflammation and epithelial–mesenchymal transition in
inflammatory bowel disease-
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Abstract: Publication date: Available online 13 May 2022Source: Toxicology in VitroAuthor(s): Mahsa Ghorbaninejad, Anna Meyfour, Samaneh Maleknia, Shabnam Shahrokh, Meghdad Abdollahpour-Alitappeh, Hamid Asadzadeh-Aghdaei
- Differential cytotoxic activity of pharmacological inhibitors of
IGF1R-related pathways in JAK2V617F driven cells-
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Abstract: Publication date: Available online 11 May 2022Source: Toxicology in VitroAuthor(s): Jaqueline Cristina Fernandes, Bruna Alves Fenerich, Antônio Bruno Alves-Silva, Natasha Peixoto Fonseca, Juan Luiz Coelho-Silva, Priscila Santos Scheucher, Eduardo Magalhães Rego, Lorena Lôbo Figueiredo-Pontes, João Agostinho Machado-Neto, Fabiola Traina
- Inhibition of serine/arginine-rich protein kinase-1 (SRPK1) prevents
cholangiocarcinoma cells induced angiogenesis-
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Abstract: Publication date: Available online 11 May 2022Source: Toxicology in VitroAuthor(s): Kittiya Supradit, Boonyakorn Boonsri, Jinchutha Duangdara, Thanvarin Thitiphatphuvanon, Chinnawut Suriyonplengsaeng, Thaned Kangsamaksin, Tavan Janvilisri, Rutaiwan Tohtong, Kiren Yacqub-Usman, Anna M. Grabowska, David O. Bates, Kanokpan Wongprasert
- B57,+B58,+and+B15+molecules&rft.title=Toxicology+in+Vitro&rft.issn=0887-2333&rft.date=&rft.volume=">Weak complex formation of adverse drug reaction-associated HLAB57, B58,
and B15 molecules-
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Abstract: Publication date: Available online 11 May 2022Source: Toxicology in VitroAuthor(s): Tomohiro Shirayanagi, Akira Kazaoka, Kenji Watanabe, Liang Qu, Naoki Sakamoto, Tyuji Hoshino, Kousei Ito, Shigeki Aoki
- Polystyrene nanoparticles incorporate into the endoplasmic reticulum and
disturb translation during meiotic maturation in mouse oocytes-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Seongwoo Park, Hyuk-Joon Jeon, Da Yi Choi, Jeong Su Oh
- Comparative study of the percutaneous permeation and bioaccumulation of
the cyclic siloxane using frozen-thawed and nonfrozen ex vivo human skin-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Krystyna Mojsiewicz-Pieńkowska, Dominika Krenczkowska, Dagmara Bazar, Bartosz Wielgomas, Krzysztof Cal, Michał Kaliszan
- Accumulated oxidative stress risk in HUVECs by chronic exposure to
non-observable acute effect levels of PM2.5-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Bingru Nan, Xia Sun, Jie Zhang, Qingyu Huang, Xi Zhang, Yanbo Li, Junchao Duan, Rui Chen, Zhiwei Sun, Heqing Shen
- Establishment of ion channel and ABC transporter assays in 3D-cultured
ReNcell VM on a 384-pillar plate for neurotoxicity potential-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Pranav Joshi, Rushabh Patel, Soo-Yeon Kang, Emily Serbinowski, Moo-Yeal Lee
- The cytotoxicity effect of a bis-MPA-based dendron, a bis-MPA-PEG
dendrimer and a magnetite nanoparticle on stimulated and non-stimulated
human blood lymphocytes-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Maria-Anthi Kakavoulia, Maria Karakota, Martha Kaloyianni, Eleftherios Halevas, Marina Sagnou, Panagiota Angeliki Galliou, Georgios Koliakos
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro
study-
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Abstract: Publication date: Available online 10 May 2022Source: Toxicology in VitroAuthor(s): Shilpa Thota, Rizwana Begum, Gagandeep Kaur, Prathyusha Bagam, Waneene Dorsey, Sanjay Batra
- Trovafloxacin drives inflammation-associated drug-induced adverse hepatic
reaction through changing macrophage polarization-
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Abstract: Publication date: Available online 9 May 2022Source: Toxicology in VitroAuthor(s): Heeyoung Yang, Tamina Park, Daeui Park, Myung-Gyun Kang
- Estrogen treatment reduced oxalate transporting activity and enhanced
migration through the involvement of SLC26A6 in lung cancer cells-
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Abstract: Publication date: Available online 29 April 2022Source: Toxicology in VitroAuthor(s): Dongun Lee, Peter Chang-Whan Lee, Jeong Hee Hong, Dong Min Shin
- Characterization of prodigiosin pigment by Serratia marcescens and the
evaluation of its bioactivities-
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Abstract: Publication date: August 2022Source: Toxicology in Vitro, Volume 82Author(s): Merve Tunca Koyun, Seda Sirin, Belma Aslim, Gokce Taner, Serap Nigdelioglu Dolanbay
- 4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell
proliferation in vitro by upregulating Cxcl1-
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Abstract: Publication date: August 2022Source: Toxicology in Vitro, Volume 82Author(s): Yahang Lin, Min He, Xiaoyun Zeng, Xia Sheng, Siyi Wang, Fengzhen Cui
- The selected epigenetic effects of phthalates: DBP, BBP and their
metabolites: MBP, MBzP on human peripheral blood mononuclear cells (In
Vitro)-
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Abstract: Publication date: Available online 27 April 2022Source: Toxicology in VitroAuthor(s): Paulina Sicińska, Ewa Jabłońska, Bożena Bukowska, Aneta Balcerczyk, Edyta Reszka
- Study on molecular mechanism of benzo (ɑ) pyrene on CMA by
HSP90ɑ and HIF-1ɑ-
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Abstract: Publication date: Available online 27 April 2022Source: Toxicology in VitroAuthor(s): Shasha Zhang, Tingting Liu, Qi Chen, Min Su, Tuya Bai, Mengdi Zhang, Yuxia Hu, Jun Li, Fuhou Chang
- Discovery of potent antitubercular agents: Design, synthesis and
biological evaluation of
4-(3-(4-substitutedpiperazin-1-yl)-quinoxalin-2-yl)-naphthalen-1-ol
analogues-
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Abstract: Publication date: Available online 27 April 2022Source: Toxicology in VitroAuthor(s): Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Kalaga Mahalakshmi Naidu, Banoth Karan Kumar, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar
- ISO 10993-23 In vitro irritation testing for medical devices:
Substantiating applicability to mild irritants and non-extractables-
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Abstract: Publication date: Available online 26 April 2022Source: Toxicology in VitroAuthor(s): Christian Pellevoisin, Kelly P. Coleman, Sebastian Hoffmann
- Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage,
mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac
fibroblasts and HUVECs-
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Abstract: Publication date: Available online 22 April 2022Source: Toxicology in VitroAuthor(s): Li Zhou, Yonglong Han, Quanjun Yang, Bo Xin, Mengyi Chi, Yan Huo, Cheng Guo, Xipeng Sun
- An in vitro approach to determine the human relevance of
anti-spermatogenic effects of 4-methylmorpholine 4-oxide, monohydrate
(NMMO) in rat reproductive toxicity studies-
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Abstract: Publication date: Available online 22 April 2022Source: Toxicology in VitroAuthor(s): Rebecca A. Clewell, Harvey J. Clewell, Matthew Linakis, Charles Easley, Jacqueline N. Langmo, Joshua Salley, Robinan Gentry, Thomas Rucker
- Differences in glucose concentration shows new perspectives in gastric
cancer metabolism-
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Abstract: Publication date: Available online 12 April 2022Source: Toxicology in VitroAuthor(s): Emerson Lucena da Silva, Felipe Pantoja Mesquita, Adrhyann Jullyanne de Sousa Portilho, Emanuel Cintra Austregésilo Bezerra, Julio Paulino Daniel, Elenn Suzany Pereira Aranha, Sarah Farran, Marne Carvalho de Vasconcellos, Maria Elisabete Amaral de Moraes, Caroline Aquino Moreira-Nunes, Raquel Carvalho Montenegro
- Benzo[a]pyrene inhibits myoblast differentiation through downregulating
the Hsp70-K2-p38MAPK complex-
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Abstract: Publication date: Available online 12 April 2022Source: Toxicology in VitroAuthor(s): Zhang Bao, Jianfeng Wang, Mingjie He, Pei Zhang, Lu Shan, Yinan Yao, Qing Wang, Liling Zheng, Huiqing Ge, Jianying Zhou
- Cytotoxicity reduction by O-nicotinoylation of antiviral
6-benzylaminopurine ribonucleosides-
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Abstract: Publication date: Available online 4 April 2022Source: Toxicology in VitroAuthor(s): Anastasia A. Zenchenko, Vladimir E. Oslovsky, Irina V. Varizhuk, Evgenia V. Karpova, Dmitry I. Osolodkin, Liubov I. Kozlovskaya, Aydar A. Ishmukhametov, Mikhail S. Drenichev
- Amending the U-SENS™ skin sensitization test method for interfering
auto-fluorescent chemicals-
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Abstract: Publication date: Available online 26 March 2022Source: Toxicology in VitroAuthor(s): Nadège Ade, Séverine Teluob, Anaelle Viricel, Cécile Piroird, Nathalie Alépée
- N-acetylcysteine protect inner hair cells from cisplatin by alleviated
celluar oxidative stress and apoptosis-
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Abstract: Publication date: Available online 26 March 2022Source: Toxicology in VitroAuthor(s): Weilong Wang, Erfang Chen, Xuerui Ding, Peiheng Lu, Jiawei Chen, Pengwei Ma, Lianjun Lu
- Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro
exposure systems for e-vapor aerosol-
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Abstract: Publication date: Available online 24 March 2022Source: Toxicology in VitroAuthor(s): J. Zhang, U. Doshi, R.L. Wolz, P. Kosachevsky, M.J. Oldham, I.G. Gillman, K.M. Lee
- Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial
cells by repressing NLRP3 inflammasome-mediated apoptosis-
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Abstract: Publication date: Available online 21 March 2022Source: Toxicology in VitroAuthor(s): Zi-tan Peng, Hui Liu
- Strategies for the evaluation of the eye irritation potential of different
types of surfactants and silicones used in cosmetic products-
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Abstract: Publication date: Available online 21 March 2022Source: Toxicology in VitroAuthor(s): Larissa de Lima Sá, Rodrigo Vieira Rodrigues, Vani M. Alves, Lorena Rigo Gaspar
- Machine learning predictive classification models for the carcinogenic
activity of activated metabolites derived from aromatic amines and
nitroaromatics-
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Abstract: Publication date: Available online 19 March 2022Source: Toxicology in VitroAuthor(s): Andrés Halabi, Elizabeth Rincón, Eduardo Chamorro
- Evaluation of an imaging-based in vitro screening platform for estrogenic
activity with OECD reference chemicals-
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Abstract: Publication date: Available online 18 March 2022Source: Toxicology in VitroAuthor(s): Britt Duijndam, Massimo Tedeschi, Wanda van der Stel, Tineke van den Hoorn, Bart van der Burg, Peter Bouwman, Jan Willem van der Laan, Bob van de Water
- Differential comparison of genotoxic effects of aristolochic acid I and II
in human cells by the mass spectroscopic quantification of γ-H2AX-
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Abstract: Publication date: Available online 17 March 2022Source: Toxicology in VitroAuthor(s): Minmin Qu, Hua Xu, Jia Chen, Bin Xu, Zhi Li, Bo Ma, Lei Guo, Qinong Ye, Jianwei Xie
- Pendulone induces apoptosis via the ROS-mediated ER-stress pathway in
human non-small cell lung cancer cells-
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Abstract: Publication date: Available online 12 March 2022Source: Toxicology in VitroAuthor(s): Wen-Chien Cheng, Ya Wen, Yen-Shuo Chiu, Chia-Hao Chou, Chen-Jen Lim, Sheng-Hao Lin, Jia-Ming Chang, Chi-Chien Lin
- A quantitative AOP of mitochondrial toxicity based on data from three cell
lines-
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Abstract: Publication date: Available online 10 March 2022Source: Toxicology in VitroAuthor(s): Cleo Tebby, Wang Gao, Johannes Delp, Giada Carta, Wanda van der Stel, Marcel Leist, Paul Jennings, Bob van de Water, Frederic Y. Bois
- Influence of bile acids on the cytotoxicity of chemicals in cultivated
human hepatocytes-
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Abstract: Publication date: Available online 6 March 2022Source: Toxicology in VitroAuthor(s): Tim Brecklinghaus, Wiebke Albrecht, Franziska Kappenberg, Julia Duda, Mian Zhang, Iain Gardner, Rosemarie Marchan, Ahmed Ghallab, Özlem Demirci Turgunbayer, Jörg Rahnenführer, Jan G. Hengstler
- Cytotoxicity assay to assess eye irritation – A comparison with other
methods and possible strategies for use-
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Abstract: Publication date: Available online 6 March 2022Source: Toxicology in VitroAuthor(s): Daniel Krakowian, Dominika Gądarowska, Anna Daniel-Wójcik, Inga Mrzyk
- 4-O-methylascochlorin-stimulated HIF-1α expression induces the epithelial
mesenchymal transition and cell survival in breast cancer cells-
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Abstract: Publication date: Available online 4 March 2022Source: Toxicology in VitroAuthor(s): Yun-Jeong Jeong, Soon-Kyung Hwang, Mi-Hee Yu, Yuna Cho, Kwon-Ho Song, Junji Magae, Eon Ju Jeon, Young-Chae Chang
- An in vitro strategy using multiple human induced pluripotent stem
cell-derived models to assess the toxicity of chemicals: A case study on
paraquat-
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Abstract: Publication date: Available online 16 February 2022Source: Toxicology in VitroAuthor(s): Carolina Nunes, Pranika Singh, Zahra Mazidi, Cormac Murphy, Aurore Bourguignon, Sara Wellens, Vidya Chandrasekaran, Sreya Ghosh, Melinda Zana, David Pamies, Aurélien Thomas, Catherine Verfaillie, Maxime Culot, Andras Dinnyes, Barry Hardy, Anja Wilmes, Paul Jennings, Regina Grillari, Johannes Grillari, Marie-Gabrielle Zurich
- Toxicological damages on copper exposure to IgM+ B cells of Nile tilapia
(Oreochromis niloticus) and mitigation of its adverse effects by β-glucan
administration-
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Abstract: Publication date: Available online 16 February 2022Source: Toxicology in VitroAuthor(s): Jianlin Chen, Yang Lei, Zijiong Dong, Shengli Fu, Lan Li, Along Gao, Liting Wu, Jianmin Ye
- Exploration of structural requirements for azole chemicals towards human
aromatase CYP19A1 activity: Classification modeling, structure-activity
relationships and read-across study-
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Abstract: Publication date: Available online 15 February 2022Source: Toxicology in VitroAuthor(s): Ana Y. Caballero Alfonso, Liadys Mora Lagares, Marjana Novic, Emilio Benfenati, Anil Kumar, Chayawan
- A promising transwell co-culture cell model for silicosis
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Abstract: Publication date: Available online 21 January 2022Source: Toxicology in VitroAuthor(s): Jiaqi Lv, Yi Zhang, Tao Yu, Haitao Yang, Yulu Li, Jingwei Xiao, Bin Li
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