 Subjects -> PHARMACY AND PHARMACOLOGY (Total: 575 journals)
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- Lack of Mitochondrial Cyp2E1 Drives Acetaminophen-induced ER
Stress-mediated Apoptosis in Mouse and Human Kidneys: Inhibition by
4-Methylpyrazole but not N-Acetylcysteine-
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Abstract: Publication date: Available online 30 November 2023Source: ToxicologyAuthor(s): Jephte Y. Akakpo, Anup Ramachandran, Barry H. Rumack, Darren P. Wallace, Hartmut Jaeschke
- Selenomethionine protects the liver from dietary deoxynivalenol exposure
via Nrf2/PPARγ-GPX4-ferroptosis pathway in mice-
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Abstract: Publication date: Available online 30 November 2023Source: ToxicologyAuthor(s): Shijie Fan, Luxi Lin, Pingyang Li, Huihui Tian, Jialu Shen, Longzhu Zhou, Qingyu Zhao, Junmin Zhang, Yuchang Qin, Chaohua Tang
- ASC/Caspase-1-activated endothelial cells pyroptosis is involved in
vascular injury induced by arsenic combined with high-fat diet-
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Abstract: Publication date: Available online 30 November 2023Source: ToxicologyAuthor(s): Qiang Su, Meng Li, Lingling Yang, Linhua Fan, Penghui Liu, Xiaodong Ying, Yannan Zhao, Xiaolin Tian, Fengjie Tian, Qian Zhao, Ben Li, Yi Gao, Yulan Qiu, Guohua Song, Xiaoyan Yan
- Exploring aryl hydrocarbon receptor (AhR) as a target for Bisphenol-A
(BPA)-induced pancreatic islet toxicity and impaired glucose homeostasis:
protective efficacy of ethanol extract of Centella asiatica-
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Abstract: Publication date: Available online 30 November 2023Source: ToxicologyAuthor(s): Oly Banerjee, Siddhartha Singh, Shilpi Kumari Prasad, Ankita Bhattacharjee, Tapan Seal, Jayanta Mandal, Sangram Sinha, Anindita Banerjee, Bithin Kumar Maji, Sandip Mukherjee
- Application of QSAR models for acute toxicity of tetrazole compounds
administrated orally and intraperitoneally in rat and mouse-
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Abstract: Publication date: Available online 30 November 2023Source: ToxicologyAuthor(s): Zhiyong Liu, Junhong Gao, Cunzhi Li, Lihong Xu, Xiaoqiang Lv, Hui Deng, Yongchao Gao, Hong Wang, Huan Li, Zhigang Wang
- An adverse outcome pathway-based approach to assess the neurotoxicity by
combined exposure to current-use pesticides-
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Abstract: Publication date: Available online 29 November 2023Source: ToxicologyAuthor(s): Tetsushi Hirano, Yoshinori Ikenaka, Kei Nomiyama, Masato Honda, Nobuo Suzuki, Nobuhiko Hoshi, Yoshiaki Tabuchi
- Further development of CometChip technology to measure DNA damage in vitro
and in vivo: comparison with the 2 gels/slide format of the standard and
enzyme-modified comet assay-
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Abstract: Publication date: Available online 29 November 2023Source: ToxicologyAuthor(s): Miguel Collia, Peter Møller, Sabine Langie, Ariane Vettorazzi, Amaya Azqueta
- Animal-free assessment of developmental toxicity: Combining PBPK modeling
with the ReproTracker assay-
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Abstract: Publication date: December 2023Source: Toxicology, Volume 500Author(s): Marjory Moreau, Amer Jamalpoor, John Carter Hall, Jeffrey Fisher, Sabine Hartvelt, Giel Hendriks, Andy Nong
- A mechanistic toxicology study to grasp the mechanics of zearalenone
estrogenicity: spotlighting aromatase and the effects of its genetic
variability-
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Abstract: Publication date: Available online 28 November 2023Source: ToxicologyAuthor(s): Florinda Perugino, Lorenzo Pedroni, Gianni Galaverna, Chiara Dall’Asta, Luca Dellafiora
- A new insight into fluoride induces cardiotoxicity in chickens: involving
the regulation of PERK/IRE1/ATF6 pathway and heat shock proteins-
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Abstract: Publication date: Available online 28 November 2023Source: ToxicologyAuthor(s): Lulu Hou, Haiyan Dong, Enyu Zhang, Hongmin Lu, Yue Zhang, Hongjing Zhao, Mingwei Xing
- In vitro toxicity of fine and coarse particulate matter on the skin,
ocular and lung microphysiological cell-culture systems-
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Abstract: Publication date: Available online 28 November 2023Source: ToxicologyAuthor(s): Dayan Yelena Guerra, Laura Margarita Valencia-Osorio, Andrés Felipe Zapata-González, Mónica Lucía Álvarez-Láinez, Elizabeth Cadavid Torres, Erick Alejandro Meneses Ramirez, Viviana Torres Osorio, Juan Sebastián Botero Valencia, Andrés Pareja López
- Toxicological Assessment of E-cigarette Flavored E-Liquids aerosols Using
Calu-3 Cells: A 3D Lung Model Approach-
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Abstract: Publication date: Available online 25 November 2023Source: ToxicologyAuthor(s): Felix Effah, John Adragna, David Luglio, Alexis Bailey, Tim Marczylo, Terry Gordon
- The variability in CYP3A4 activity determines the metabolic kinetic
characteristics of ketamine-
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Abstract: Publication date: Available online 24 November 2023Source: ToxicologyAuthor(s): Mengfang Li, Qingqing Li, Dan Lin, Xiang Zheng, Lehao Jin, Jianping Cai, Guoxin Hu, Jianchang Qian
- Comprehensive analysis of the impact of emerging flame retardants on
prostate cancer progression: The potential molecular mechanisms and immune
infiltration landscape.-
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Abstract: Publication date: Available online 24 November 2023Source: ToxicologyAuthor(s): Xinchi Xu, Dong Zhang, Kai Zhao, Zhanpeng Liu, Xiaohan Ren, Xu Zhang, Zhongwen Lu, Chao Qin, Jiawei Wang, Shangqian Wang
- Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro
through Nrf2/HO-1 and Akt/mTOR pathways-
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Abstract: Publication date: Available online 23 November 2023Source: ToxicologyAuthor(s): Yue Shen, Xinying Li, Hongyan Wang, Yicheng Wang, Liqing Tao, Pingping Wang, Heng Zhang
- Examining the immunotoxicity of oil sands process affected waters using a
human macrophage cell line-
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Abstract: Publication date: Available online 23 November 2023Source: ToxicologyAuthor(s): Sunanda Paul, Nora A.S. Hussain, Dustin M.E. Lillico, Monsuru A. Suara, Soliu O. Ganiyu, Mohamed Gamal El-Din, James L. Stafford
- Use of a Polymeric Implant System to Assess the Neurotoxicity of Subacute
Exposure to 2,2',5,5'-Tetrachlorobiphenyl-4-ol, a Human Metabolite of PCB
52, in Male Adolescent Rats-
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Abstract: Publication date: Available online 22 November 2023Source: ToxicologyAuthor(s): Hui Wang, Amanda J Bullert, Xueshu Li, Hanna Stevens, Aloysius J Klingelhutz, James A Ankrum, Andrea Adamcakova-Dodd, Peter S Thorne, Hans-Joachim Lehmler
- Development of a read-across-derived classification model for the
predictions of mutagenicity data and its comparison with traditional QSAR
models and expert systems-
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Abstract: Publication date: Available online 21 November 2023Source: ToxicologyAuthor(s): Sapna Kumari Pandey, Kunal Roy
- Secreted cyclophilin A is non-genotoxic but acts as a tumor promoter
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Abstract: Publication date: Available online 20 November 2023Source: ToxicologyAuthor(s): Anastasiia Kalinina, Leila Tilova, Kirill Kirsanov, Ekaterina Lesovaya, Ekaterina Zhidkova, Timur Fetisov, Galina Ilyinskaya, Marianna Yakubovskaya, Dmitry Kazansky, Ludmila Khromykh
- Nonivamide inhibits proliferation of human corneal epithelial cells by
inducing cell cycle arrest and oxidative stress-
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Abstract: Publication date: Available online 19 November 2023Source: ToxicologyAuthor(s): Haiyun Li, Qian Zhang, Yi Zhang, Sida Zhang, Ruihua Zhang, Dong Chen, Jingjing Shi, Jianfu Xu, Liqin Li
- Increased m6A-RNA Methylation and Demethylase FTO Suppression is
Associated with Silica-induced Pulmonary Inflammation and Fibrosis-
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Abstract: Publication date: Available online 16 November 2023Source: ToxicologyAuthor(s): Yunyi Xu, Liqun Wang, Rui Qian, Manyu Zhao, Xuxi Chen, Donglei Sun, Ye Wang, Weibo Cheng, Yiping Chen, Qiurong He, Yi Dai, Yuqin Yao
- Arsenic induces metabolome remodeling in mature human adipocytes
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Abstract: Publication date: Available online 11 November 2023Source: ToxicologyAuthor(s): Marie Gasser, Sébastien Lenglet, Nasim Bararpour, Tatjana Sajic, Julien Vaucher, Kim Wiskott, Marc Augsburger, Tony Fracasso, Federica Gilardi, Aurélien Thomas
- Pesticide Mediated Silent Neurotoxicity and Its Unmasking: An Update on
Recent Progress-
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Abstract: Publication date: Available online 7 November 2023Source: ToxicologyAuthor(s): Ankita Srivastava, Ankur Kumar Srivastava, Abhishek Pandeya, Aditya Bhushan Pant
- In Vitro Binding Analysis of Legacy-Linear and New Generation-Cyclic
Perfluoro-Alkyl Substances on Sex Hormone Binding Globulin and Albumin,
Suggests Low Impact on Serum Hormone Kinetics of Testosterone-
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Abstract: Publication date: Available online 4 November 2023Source: ToxicologyAuthor(s): Angela Pavan, Laura Cendron, Andrea Di Nisio, Federica Pedrucci, Iva Sabovic, Alessandro Scarso, Alberto Ferlin, Alessandro Angelini, Carlo Foresta, Luca De Toni
- Genotoxicity assessment of 1,4-Anhydro-4-seleno-D-talitol (SeTal) in human
liver HepG2 and HepaRG cells-
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Abstract: Publication date: Available online 2 November 2023Source: ToxicologyAuthor(s): Raffaella di Vito, Mattia Acito, Cristina Fatigoni, Carl H. Schiesser, Michael J. Davies, Francesca Mangiavacchi, Milena Villarini, Claudio Santi, Massimo Moretti
- Non-coding RNAs: A new frontier in Benzene-mediated toxicity
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Abstract: Publication date: Available online 2 November 2023Source: ToxicologyAuthor(s): Amir Hosein Sanjari Nia, Mehran Reyhani-Ardabili, Maryam Sheikhvand, Saeid Bagheri-Mohammadi, Hadi Niknejad, Hassan Rasoulzadeh, Abolfazl Movafagh, Sam Kharazi Neghad, Mohammad Baniasadi, Ahad Ashraf-Asgarabad, Mobina Hosseini, Seyed Mohsen Aghaei-Zarch
- Considerations for future quantitative structure-activity relationship
(QSAR) modelling for heavy metals – A case study of mercury-
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Abstract: Publication date: Available online 2 November 2023Source: ToxicologyAuthor(s): Rebecca von Hellfeld, Christoph Gade, Neil Vargesson, Astley Hastings
- Pleural inflammatory response, mesothelin content and DNA damage in mice
at one-year after intra-pleural carbon nanotube administration-
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Abstract: Publication date: November 2023Source: Toxicology, Volume 499Author(s): Regitze Sølling Wils, Nicklas Raun Jacobsen, Ulla Vogel, Martin Roursgaard, Annie Jensen, Peter Møller
- Hexabromocyclododecane (HBCD) induced PANoptosis of chondrocytes via
activation of the NLRP3 inflammasome and decreased the exercise ability of
mice in vivo-
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Abstract: Publication date: Available online 1 November 2023Source: ToxicologyAuthor(s): Tian Fujun, Sun Jiabao, Yue Jianmin, Wang Qiyu
- Etoricoxib enhances aryl hydrocarbon receptor activity
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Abstract: Publication date: Available online 26 October 2023Source: ToxicologyAuthor(s): Hsiao-ho Fang, Jiun Hsu, Jyan-Gwo Joseph Su
- Recombinant Klotho alleviates vancomycin-induced acute kidney injury by
upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis-
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Abstract: Publication date: Available online 25 October 2023Source: ToxicologyAuthor(s): MengMeng Wang, Yue Zhou, GuoXiang Hao, Yue E Wu, Rui Yin, Yi Zheng, Wei Zhao
- Assessing micro- and nanoplastics toxicity using rodent models:
investigating potential mitochondrial implications-
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Abstract: Publication date: Available online 24 October 2023Source: ToxicologyAuthor(s): Mónica G. Silva, Maria Manuel Oliveira, Francisco Peixoto
- Cytomodulatory characteristics of Granulocyte-Macrophage
Colony-Stimulating Factor (GM-CSF) against cypermethrin on skin fibroblast
cells (HFF-1)-
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Abstract: Publication date: Available online 21 October 2023Source: ToxicologyAuthor(s): Shaghayegh Aghajanshakeri, Ramin Ataee, Mohammad Karami, Shahin Aghajanshakeri, Mohammad Shokrzadeh
- Lead exposure induces neuronal apoptosis via NFκB p65/RBBP4/Survivin
signaling pathway-
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Abstract: Publication date: Available online 20 October 2023Source: ToxicologyAuthor(s): Hui Chen, Wei Zhang, Song Luo, Yanshu Li, Qian Zhu, Yongli Xia, Hong Tan, Ying Bian, Yaobing Li, Jianmin Ma, Wei Chen, Xietian Luo, Gaochun Zhu
- Increasing Confidence in New Approach Methodologies for Inhalation Risk
Assessment with Multiple End Point Assays Using 5-day Repeated Exposure to
1,3-dichloropropene-
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Abstract: Publication date: Available online 18 October 2023Source: ToxicologyAuthor(s): Iru Paudel, A. Rasim Barutcu, Raymond Samuel, Marjory Moreau, Scott D. Slattery, Leslie Recio
- Role of myo-inositol in acute kidney injury induced by cisplatin
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Abstract: Publication date: Available online 18 October 2023Source: ToxicologyAuthor(s): Yu-hong Xie, Ling Wang, Ming-liang Li, Zhi-cheng Gong, Jie Du
- Synergism in actions of HBV with aflatoxin in cancer development
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Abstract: Publication date: Available online 18 October 2023Source: ToxicologyAuthor(s): Joshua Jin, Valentina L. Kouznetsova, Santosh Kesari, Igor F. Tsigelny
- Restoration of PM2.5-induced spermatogonia GC-1 cellular damage by
parthenolide via suppression of autophagy and inflammation: an in vitro
study.-
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Abstract: Publication date: Available online 17 October 2023Source: ToxicologyAuthor(s): Hyo Jin Gu, Jin Seop Ahn, Gi Jeong Ahn, Seung Hee Shin, Buom-Yong Ryu
- Subchronic exposure to Di-(2-ethylhexyl) phthalate (DEHP) elicits
blood–brain barrier dysfunction and cerebral inflammation in male
C57BL/6 J mice-
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Abstract: Publication date: Available online 17 October 2023Source: ToxicologyAuthor(s): Wen-qiang Ren, Nuo Liu, Yan Shen, Xian-yan Wang, Qiong Zhou, Chen Rui, Xiao-han Yang, Sheng-long Cao, Ling-yu Li, Yan Wang, Qu-nan Wang
- Emerging Organophosphate Ester Resorcinol bis(Diphenyl Phosphate) Exerts
Estrogenic Effects via Estrogen Receptor Pathways-
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Abstract: Publication date: Available online 11 October 2023Source: ToxicologyAuthor(s): Yue Xie, Qi Zhang, Lu Chen, Fangfang Li, Minjie Li, Liang-Hong Guo
- Deficiency of spns1 Exacerbates Per- and Polyfluoroalkyl Substances
Mediated Hepatic Toxicity and Steatosis in Zebrafish (Danio rerio)-
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Abstract: Publication date: Available online 6 October 2023Source: ToxicologyAuthor(s): Sashi Gadi, Suryakant Niture, Hieu Hoang, Qi Qi, Charles Hatcher, Xiaoyan Huang, Jamil Haider, Derek C. Norford, TinChung Leung, Keith E. Levine, Deepak Kumar
- Preconception and developmental DEHP exposure alter liver metabolism in a
sex-dependent manner in adult mouse offspring-
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Abstract: Publication date: Available online 6 October 2023Source: ToxicologyAuthor(s): Nicole Robles-Matos, Enrico Radaelli, Rebecca A. Simmons, Marisa S. Bartolomei
- Pb inhibited C2C12 myoblast differentiation by regulating HDAC2
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Abstract: Publication date: Available online 4 October 2023Source: ToxicologyAuthor(s): Xiaozhen Gu, Nan Shen, Chengqing Huang, Hui-Li Wang
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