Subjects -> ENVIRONMENTAL STUDIES (Total: 913 journals)
    - ENVIRONMENTAL STUDIES (810 journals)
    - POLLUTION (31 journals)
    - TOXICOLOGY AND ENVIRONMENTAL SAFETY (54 journals)
    - WASTE MANAGEMENT (18 journals)

ENVIRONMENTAL STUDIES (810 journals)            First | 1 2 3 4 5     

Showing 601 - 378 of 378 Journals sorted alphabetically
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis     Hybrid Journal   (Followers: 5)
Mutation Research/Genetic Toxicology and Environmental Mutagenesis     Hybrid Journal   (Followers: 8)
Nano Select     Open Access  
Nanotechnology for Environmental Engineering     Hybrid Journal  
Nativa     Open Access  
Natur und Recht     Hybrid Journal   (Followers: 7)
Natural Areas Journal     Full-text available via subscription   (Followers: 10)
Natural Hazards     Hybrid Journal   (Followers: 53)
Natural Resources     Open Access  
Natural Resources & Engineering     Hybrid Journal  
Natural Resources and Environmental Issues     Open Access   (Followers: 2)
Nature and Culture     Full-text available via subscription   (Followers: 11)
Nature-Based Solutions     Open Access  
Nepal Journal of Environmental Science     Open Access  
NeuroToxicology     Hybrid Journal   (Followers: 1)
Neurotoxicology and Teratology     Hybrid Journal   (Followers: 3)
NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy     Full-text available via subscription   (Followers: 2)
New Zealand Journal of Environmental Law     Full-text available via subscription   (Followers: 4)
NJAS : Wageningen Journal of Life Sciences     Hybrid Journal  
Novos Cadernos NAEA     Open Access  
npj Urban Sustainability     Open Access  
Observatorio Medioambiental     Open Access  
Occupational and Environmental Medicine     Hybrid Journal   (Followers: 18)
Ochrona Srodowiska i Zasobów Naturalnych : Environmental Protection and Natural Resources     Open Access  
Oecologia     Hybrid Journal   (Followers: 54)
Oikos     Hybrid Journal   (Followers: 55)
One Earth     Hybrid Journal   (Followers: 2)
One Ecosystem     Open Access  
Open Environmental Research Journal     Open Access   (Followers: 1)
Open Journal of Marine Science     Open Access   (Followers: 6)
Open Journal of Modern Hydrology     Open Access   (Followers: 5)
Our Nature     Open Access   (Followers: 1)
Pace Environmental Law Review     Open Access   (Followers: 4)
Packaging, Transport, Storage & Security of Radioactive Material     Hybrid Journal   (Followers: 2)
Palaeobiodiversity and Palaeoenvironments     Hybrid Journal   (Followers: 3)
Particle and Fibre Toxicology     Open Access   (Followers: 2)
Pastos y Forrajes     Open Access  
Peer Community Journal     Open Access   (Followers: 4)
Perspectives in Ecology and Conservation     Full-text available via subscription   (Followers: 1)
Pharmacology & Therapeutics     Hybrid Journal   (Followers: 3)
Pharmacology Biochemistry and Behavior     Hybrid Journal   (Followers: 2)
Physio-Géo     Open Access   (Followers: 1)
Pittsburgh Journal of Environmental and Public Health Law     Open Access  
Planet     Open Access   (Followers: 4)
Planeta Amazônia : Revista Internacional de Direito Ambiental e Políticas Públicas     Open Access  
Planning & Environmental Law: Issues and decisions that impact the built and natural environments     Hybrid Journal   (Followers: 6)
Plant Ecology & Diversity     Partially Free   (Followers: 13)
Plant Knowledge Journal     Open Access   (Followers: 1)
Plant, Cell & Environment     Hybrid Journal   (Followers: 8)
Plant-Environment Interactions     Open Access  
Plants, People, Planet     Open Access   (Followers: 1)
Polar Journal     Hybrid Journal   (Followers: 2)
Political Studies     Hybrid Journal   (Followers: 42)
Political Studies Review     Hybrid Journal   (Followers: 18)
Population and Environment     Hybrid Journal   (Followers: 6)
Population Ecology     Hybrid Journal   (Followers: 12)
Practice Periodical of Hazardous, Toxic, and Radioactive Waste Management     Full-text available via subscription  
Presence: Virtual and Augmented Reality     Hybrid Journal   (Followers: 2)
Proceedings of the Institution of Civil Engineers - Waste and Resource Management     Hybrid Journal   (Followers: 1)
Proceedings of the Institution of Mechanical Engineers Part M: Journal of Engineering for the Maritime Environment     Hybrid Journal   (Followers: 3)
Proceedings of the International Academy of Ecology and Environmental Sciences     Open Access   (Followers: 1)
Proceedings of the Vertebrate Pest Conference     Open Access  
Process Integration and Optimization for Sustainability     Hybrid Journal  
Process Safety and Environmental Protection     Hybrid Journal   (Followers: 4)
Producción + Limpia     Open Access  
Progress in Disaster Science     Open Access   (Followers: 1)
Progress in Industrial Ecology, An International Journal     Hybrid Journal   (Followers: 2)
Projets de Paysage     Open Access  
Psychological Assessment     Full-text available via subscription   (Followers: 12)
Public Money & Management     Hybrid Journal   (Followers: 7)
Quaternary     Open Access  
Recursos Rurais     Open Access  
REDER : Revista de Estudios Latinoamericanos sobre Reducción del Riesgo de Desastres     Open Access  
Regional Environmental Change     Open Access   (Followers: 2)
Regional Sustainability     Open Access   (Followers: 1)
Rekayasa     Open Access  
Remediation Journal     Hybrid Journal   (Followers: 8)
Remote Sensing Applications : Society and Environment     Full-text available via subscription   (Followers: 9)
Remote Sensing Letters     Hybrid Journal   (Followers: 46)
Rendiconti Lincei     Hybrid Journal  
Renewable Energy and Environmental Sustainability     Open Access   (Followers: 1)
Renewable Energy Focus     Full-text available via subscription   (Followers: 7)
Research & Reviews : Journal of Ecology     Full-text available via subscription   (Followers: 3)
Research and Practice for Persons with Severe Disabilities     Full-text available via subscription   (Followers: 3)
Research Journal of Environmental Sciences     Open Access   (Followers: 2)
Research Journal of Environmental Toxicology     Open Access   (Followers: 2)
Resources     Open Access  
Resources and Environment     Open Access  
Resources, Conservation & Recycling     Hybrid Journal   (Followers: 20)
Resources, Conservation & Recycling : X     Open Access   (Followers: 1)
Resources, Conservation & Recycling Advances     Open Access   (Followers: 1)
Rethinking Ecology     Open Access  
Reuse/Recycle Newsletter     Hybrid Journal  
Review of Agricultural, Food and Environmental Studies     Hybrid Journal  
Review of Environmental Economics and Policy     Hybrid Journal   (Followers: 11)
Revista AIDIS de Ingeniería y Ciencias Ambientales. Investigación, desarrollo y práctica     Open Access  
Revista Ambivalências     Open Access  
Revista Brasileira de Ciências Ambientais     Open Access  
Revista Brasileira de Meio Ambiente     Open Access  
Revista Chapingo. Serie Ciencias Forestales y del Ambiente     Open Access  
Revista Ciência, Tecnologia & Ambiente     Open Access  
Revista de Ciencias Ambientales     Open Access  
Revista de Direito Ambiental e Socioambientalismo     Open Access  
Revista de Direito e Sustentabilidade     Open Access  
Revista de Gestão Ambiental e Sustentabilidade - GeAS     Open Access  
Revista de Investigación en Agroproducción Sustentable     Open Access  
Revista de Salud Ambiental     Open Access  
Revista ECOVIDA     Open Access   (Followers: 4)
Revista Eletrônica de Gestão e Tecnologias Ambientais     Open Access  
Revista Geama     Open Access  
Revista Hábitat Sustenable     Open Access  
Revista Iberoamericana Ambiente & Sustentabilidad     Open Access  
Revista Kawsaypacha: Sociedad y Medio Ambiente     Open Access  
Revista Laborativa     Open Access  
Revista Meio Ambiente e Sustentabilidade     Open Access  
Revista Mundi Meio Ambiente e Agrárias     Open Access  
Revista Verde de Agroecologia e Desenvolvimento Sustentável     Open Access   (Followers: 2)
Rivista di Studi sulla Sostenibilità     Full-text available via subscription   (Followers: 1)
RUDN Journal of Ecology and Life Safety     Open Access  
Russian Journal of Ecology     Hybrid Journal   (Followers: 1)
Safety Science     Hybrid Journal   (Followers: 29)
San Francisco Estuary and Watershed Science     Open Access  
SAR and QSAR in Environmental Research     Hybrid Journal   (Followers: 1)
Saúde e Meio Ambiente : Revista Interdisciplinar     Open Access  
Scandinavian Journal of Work, Environment & Health     Partially Free   (Followers: 13)
Science of The Total Environment     Hybrid Journal   (Followers: 36)
Sciences Eaux & Territoires : la Revue du Cemagref     Open Access  
Social and Environmental Accountability Journal     Hybrid Journal   (Followers: 3)
Sociedad y Ambiente     Open Access  
Soil and Sediment Contamination: An International Journal     Hybrid Journal   (Followers: 3)
Soil and Tillage Research     Hybrid Journal   (Followers: 9)
South Australian Geographical Journal     Open Access  
South Pacific Journal of Natural and Applied Sciences     Hybrid Journal  
Southern African Journal of Environmental Education     Open Access  
Southern Forests : a Journal of Forest Science     Hybrid Journal   (Followers: 3)
Sriwijaya Journal of Environment     Open Access  
Stochastic Environmental Research and Risk Assessment     Hybrid Journal   (Followers: 4)
Strategic Planning for Energy and the Environment     Hybrid Journal   (Followers: 4)
Studies in Conservation     Hybrid Journal   (Followers: 16)
Sustainability     Open Access   (Followers: 21)
Sustainability Agri Food and Environmental Research     Open Access   (Followers: 4)
Sustainability in Environment     Open Access   (Followers: 2)
Sustainable and Resilient Infrastructure     Hybrid Journal  
Sustainable Cities and Society     Hybrid Journal   (Followers: 22)
Sustainable Development     Hybrid Journal   (Followers: 14)
Sustainable Development Law & Policy     Open Access   (Followers: 12)
Sustainable Development Strategy and Practise     Open Access   (Followers: 4)
Sustainable Horizons     Full-text available via subscription   (Followers: 1)
Sustainable Technology and Entrepreneurship     Full-text available via subscription   (Followers: 2)
Sustinere : Journal of Environment and Sustainability     Open Access  
TECHNE - Journal of Technology for Architecture and Environment     Open Access   (Followers: 11)
Tecnogestión     Open Access  
Territorio della Ricerca su Insediamenti e Ambiente. Rivista internazionale di cultura urbanistica     Open Access  
The Historic Environment : Policy & Practice     Hybrid Journal   (Followers: 4)
The International Journal on Media Management     Hybrid Journal   (Followers: 7)
The Ring     Open Access  
Theoretical Ecology     Hybrid Journal   (Followers: 15)
Toxicologic Pathology     Hybrid Journal   (Followers: 19)
Toxicological & Environmental Chemistry     Hybrid Journal   (Followers: 2)
Toxicological Sciences     Hybrid Journal   (Followers: 11)
Toxicology     Hybrid Journal   (Followers: 19)
Toxicology and Applied Pharmacology     Hybrid Journal   (Followers: 25)
Toxicology and Industrial Health     Hybrid Journal   (Followers: 6)
Toxicology in Vitro     Hybrid Journal   (Followers: 12)
Toxicology Letters     Hybrid Journal   (Followers: 16)
Toxicology Mechanisms and Methods     Hybrid Journal   (Followers: 9)
Toxicon     Hybrid Journal   (Followers: 5)
Toxicon : X     Open Access  
Toxin Reviews     Hybrid Journal  
Transactions on Environment and Electrical Engineering     Open Access  
Transportation Research Part D: Transport and Environment     Hybrid Journal   (Followers: 28)
Transportation Safety and Environment     Open Access   (Followers: 1)
Transylvanian Review of Systematical and Ecological Research     Open Access  
Trends in Ecology & Evolution     Full-text available via subscription   (Followers: 230)
Trends in Environmental Analytical Chemistry     Hybrid Journal   (Followers: 3)
Trends in Pharmacological Sciences     Full-text available via subscription   (Followers: 21)
Tropicultura     Open Access  
Turkish Journal of Engineering and Environmental Sciences     Open Access   (Followers: 1)
UCLA Journal of Environmental Law and Policy     Open Access   (Followers: 1)
UD y la Geomática     Open Access  
Universidad y Ciencia     Open Access  
Universidad y Ciencia     Open Access  
UNM Environmental Journals     Open Access  
Urban Studies     Hybrid Journal   (Followers: 68)
Urban Transformations     Open Access  
Veredas do Direito : Direito Ambiental e Desenvolvimento Sustentável     Open Access  
VertigO - la revue électronique en sciences de l’environnement     Open Access   (Followers: 1)
Villanova Environmental Law Journal     Open Access  
Waste Management & Research     Hybrid Journal   (Followers: 6)
Water Conservation Science and Engineering     Hybrid Journal   (Followers: 1)
Water Environment Research     Full-text available via subscription   (Followers: 43)
Water International     Hybrid Journal   (Followers: 19)
Water Security     Hybrid Journal   (Followers: 5)
Water, Air, & Soil Pollution : Focus     Hybrid Journal   (Followers: 7)
Water, Air, & Soil Pollution     Open Access   (Followers: 21)
Weather and Forecasting     Hybrid Journal   (Followers: 43)
Weather, Climate, and Society     Hybrid Journal   (Followers: 16)
Web Ecology     Open Access   (Followers: 3)
Wetlands     Hybrid Journal   (Followers: 24)
Wilderness & Environmental Medicine     Hybrid Journal   (Followers: 2)

  First | 1 2 3 4 5     

Similar Journals
Journal Cover
Sustainability in Environment
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2470-637X - ISSN (Online) 2470-6388
Published by Scholink Homepage  [7 journals]
  • Effects of Massage Therapy and the Role of Physical Activity as an
           Improvement in the Psycho-Physical State of the Individual and Reduction
           of Pain and Anxiety during the COVID-19 Pandemic Systematic Review

    • Authors: Dario Furnari, Nadya Khan, Melissa Delaney, Margaret Cerna, Himanshu Tiwari, V.V Manjula Kumari, Khaled Hamlaoui, Sebastien Lagree, Amy Peace, Megan Owens, Shanee Lee Scott, Tonja Latham Gustin, Tanya Crowle, Susana Sanchez, Aliaksandra Eyring, Elena Talyanova, Monika Milczarek, Abdulrahim Aljayar, Juan Jose Ariet, B?a?Hab Me?bHNK, Heather Perren, Timothy Lee, Sandy Wanna, Sergey Petrov, Mia M. Michel, Clarice Santos, Charlie Peebles, Chutima Halg, Erik Dalton, Laura Goncalves, Angela Maria Kunrath, Roberto Simon Luna, Maria Sol Rodriguez
      First page: 1
      Abstract: Deep skills: positive mind neuroscience of exercise to counter Covid 19Memory and Learning in the time of Covid 19We must begin to lose our memory, even if only occasionally, to understand that memory is what fills our lives. Life without memory is not life. Our memory is our consistency, our reason, our feeling, even our action. Without her we are nothing.
      Luis Bunuel
      Memory is a wonderful mechanism, a means of transporting us back in time. We can go back a moment, or a large part of life. Sometimes not perfect, sometimes not authentic, sometimes with nuanced details, memory is however the system that allows us to recall the information we have stored and learned from both the external and internal environment. It is the experience that changes us, the contact with the environment that changes our behavior through a series of structural and functional changes in our nervous system. The last challenge of neuroscience is precisely to better understand the complexity of these mechanisms and how complex phenomena such as learning and memory can occur.
      Although the changes that occur within the individual brain cells can be relatively simple, considering that the brain is made up of many billions of neurons, the overall phenomenon is certainly very complex and makes the isolation and identification of the specific changes responsible of a certain really difficult memory. Similarly, although the elements of a specific learning task may be simple, its implications for the organism can be very complex (Carlson, 2002).
      From a neurobiological point of view, learning and memory are adaptations to the environment of the brain circuits that allow us to respond appropriately to situations we have previously experienced. Hence, learning (the process by which the nervous system acquires new information and experiences) and memory (the ability to retain, retain and recall this information) represent the main mechanisms through which environmental events shape behavior. The experiences are not simply “accumulated” in the brain, but are capable of causing plastic modifications in our nervous system and of altering the circuits involved in our most sophisticated functions; in this way they change the way we act, think, perceive, plan. Although learning and memory are two closely related functions, they have temporal sequences and nervous mechanisms that do not always coincide. From a neurophysiological point of view, in fact, the learning process is essentially functional, ie entrusted to reverberant circuits and unstable morphological modifications, while the memory process is structural and presupposes stable morphological modifications. These changes are accompanied by an increase in protein synthesis and consist of an increase in the number and volume of the dendritic spines (Gasbarri & Tomaz, 2005).
      The importance of understanding the mechanisms that underlie the memory process, and the hope of being able to intervene when they are damaged, is therefore easily understood: they depend on the quality of life and the survival of the individual. This type of considerations helps to make the field of research on the mechanisms underlying memory particularly active. Many of these studies are carried out on animal models, but one wonders how much these studies are predictive of human reality both in terms of memory neurobiology (think, for example, of the different and more extensive development of the cortex in humans), and regarding the effect of drugs of potential therapeutic use in memory disorders. Some types of memory, however, have common characteristics in animals and humans, and animal models make it easier to study simple forms of learning and memory - such as the conditioned blink reflex - which are completely human similar to those studied in small mammals. Furthermore, the preliminary study on the animal very often allows to safeguard thousands of human lives and to avoid, for example, the experimentation of drugs on the ex-abducted man. Learning is the process by which experiences modify our nervous system and therefore our behavior. The primary function of the ability to learn is to develop behaviors suitable for a constantly changing environment. Experiences are able to change the way we perceive, act, think and plan. The ability of our nervous system to change in relation to experience is called synaptic plasticity and consists of a structural and functional change in the nervous structures which is reflected in changes in the processes of perception, memory, thought, planning and action.
      Learning phenomena can be distinguished in:
      Non-associative learning: habit and awareness
      Associative learning: perceptual learning, stimulus response learning (classical / Pavlonian conditioning), instrumental / operative conditioning by trial and error, motor learning, relational learning. Although the understanding of the mechanisms responsible for learning and other plastic modifications that take place in the adult brain still remains the subject of debate, there is broad consensus on the concept that at the basis of these phenomena there are modifications finely regulated by the strength of the synapses (Madison et al., 1991).
      While in development, the changes are based on the reorganization of the connections that already exist between the cells, the strength of the synapses can also change in adulthood. The cellular mechanisms underlying these changes are constituted by transient modifications of the synaptic neurotransmission processes, while in the case of more lasting modifications they are constituted by changes in the processes of gene expression. Even after development is complete, the ability to change the organization of the nervous circuits of the cortex is not completely lost, but this ability decreases considerably (Bliss & Collingridge, 1993).
      PubDate: 2022-05-02
      DOI: 10.22158/se.v7n2p1
      Issue No: Vol. 7, No. 2 (2022)
       
  • Manual Therapycombined with Functional Exercise in the Treatment of the
           Mainpathologies of Aging: A Quantitative-Qualitative Randomized Clinical
           Trial

    • Authors: Dario Furnari, Nadya Khan, Melissa Delaney, Margaret Cerna, Himanshu Tiwari, V. V Manjula Kumari, Khaled Hamlaoui, Sebastien Lagree, Amy Peace, Shanee Lee Scott1, Tonja Latham Gustin, Tanya Crowle, Susana Sanchez, Aliaksandra Eyring, Elena Talyanova, Monika Milczarek, Abdulrahim Aljayar, Juan Jose Ariet, B?a?Hab Me?bHNK, Sandy Wanna, Sergey Petrov, Mia M. Michel, Clarice Santos, Charlie Peebles, Chutima Halg, Erik Dalton, Laura Goncalves, Angela Maria Kunrath, Roberto Simon Luna, Maria Sol Rodriguez
      First page: 25
      Abstract: Aging (or senescence) is that period of life, characterized by a series of progressive irreversible changes affecting the cells, tissues and organs, therefore of the wholeorganism, whichbeginwhenthis, once developmentis complete, hasreached aadulthood, and continue to manifestthemselves, culminating in death, whichoccursas a consequence of them and not by the intervention of external factors.
      PubDate: 2022-05-02
      DOI: 10.22158/se.v7n2p25
      Issue No: Vol. 7, No. 2 (2022)
       
  • Neuroscience and Cognitive Rehabilitation: The Role of Cognitive Training,
           Musculoskeletal Therapy in Neuroplasticity Models for Advanced
           Rehabilitation

    • Authors: Dario Furnari, Nadya Khan, Melissa Delaney, Margaret Cerna, Himanshu Tiwari, V.V Manjula Kumari, Khaled Hamlaoui, Sebastien Lagree, Amy Peace, Megan Owens, Shanee Lee Scott, Tanya Crowle, Susana Sanchez, Elena Talyanova, Monika Milczarek, Abdulrahim Aljayar, Sergey Petrov, Juan Jose Ariet, B?a?Hab Me?bHNK, Sandy Wanna, Mia M. Michel, Clarice Santos, Charlie Peebles, Chutima Halg, Erik Dalton, Laura Goncalves, Roberto Simon Luna, Maria Sol Rodriguez
      First page: 28
      Abstract: Learning to write requires a good functional, motor, intellectual and level affective and presupposes the knowledge and appropriate use of language. A complex of skills that the subject does not always possess and which makes him vulnerable to school failure. The state of failure can provoke inattention, demotivation, behavioral disorders with possible manifestations of aggression or apathy.
      PubDate: 2022-05-02
      DOI: 10.22158/se.v7n2p28
      Issue No: Vol. 7, No. 2 (2022)
       
  • Explosive Hypertrophy Development: 5RD Method, Advanced Way for Explosive
           Hypertrophy, Cases Report Series Research

    • Authors: Khaled Hamlaoui, Dario Furnari, Nadya Khan
      First page: 34
      Abstract: The knowledge of muscle function plays a major role in bodybuilding training and makes big difference for bodybuilders.Muscle monitoring is of great interest in areas such as clinical assessment, and sport science. Understanding, ideally quantifying, when a muscle state has changed in relation to whole body motion can assist in physical training and muscle conditioning.There are lot of different methods to gain muscle mass and improve weak parts; bodybuilders been using those methods for decades such: drop-set, rest-pause, super-set, tri-set, giant sets, contrast time, multi hold pump set, intra set load contrast, regressive range of motion, iso dynamic contrastOur method is based on scientific work; our main goal is to improve bodybuilder’s weak muscles and increase muscle mass in very short period of time, to asses our work we used electromyography (EMG) to assess the skeletal muscles activity and ultrasonography (US) to measure muscle thickness.Bodybuilding is the use of progressive resistance exercise to develop the musculature, is the process of developing muscle fibres through the combination of weight training, increased caloric intake, and rest. Bodybuilding decreases risk of developing diseases, Improve Mental Health, simply Weight training exercise, aerobic exercise and right nutrition have beneficial effects for strong mind and body. Muscle hypertrophy is a term for the growth and increase of the size of muscle cells. Hypertrophy is, by definition, the enlargement of an organ or tissue from the increase in size of its cells. Not to be confused with hyperplasia, the process of increasing the number of cells, hypertrophy is the process of increasing the size of the cells that are already there.By that a hormonal response is triggered, so a release of growth factor, cortisol, and testosterone. Growth factors help stimulate muscle hypertrophy while testosterone increases protein synthesis. This process makes satellite cells multiplying and their daughter cells go to the damaged tissue. To build muscle through weight lifting, you need to have both mechanical damage and metabolic fatigue. When you lift a heavy weight, the contractile proteins in the muscles must generate force to overturn the resistance provided by the weight.
      PubDate: 2022-05-05
      DOI: 10.22158/se.v7n2p34
      Issue No: Vol. 7, No. 2 (2022)
       
  • Van Lohuizen Syndrome, A Late-Diagnosed Case in an 18 Years-Old Female
           Case Reports in Orthopedic Research Clinical Trials in Orthopaedic Surgery
           

    • Authors: Abdulrahim Aljayar, Dario Furnari, James Stoxen, Khaled Hamlaoui, Nadya Khan, Charlie Peebles
      First page: 40
      Abstract: Cutis Marmorata Telangiectatica Congenita is a very rare birth defect involving cutaneous blood vessels. Of unknown cause, uncertain pathophysiology, unclear epidemiology. Described as a localized, or generalized marbled skin appearance (cutis marmarota), in addition to the skin, it may involve any other body organs, with, or without a wide variety of associated congenital anomalies. Kato van Lohuizen described the first case in 1922. Since then, there have been less than 300 cases reported worldwide to date. We are adding one more case, and the first reported in Libya.
      PubDate: 2022-05-05
      DOI: 10.22158/se.v7n2p40
      Issue No: Vol. 7, No. 2 (2022)
       
  • Metformin and Exercise; the Effects of Metformin in the Body Building to
           Minimize the Effects of the Use of Anabolics: Case Report for a Randomized
           Controlled Trial

    • Authors: Khaled Hamlaoui, Dario Furnari, Nadya Khan
      First page: 48
      Abstract: Metformin is an oral antidiabetic used in the treatment of type 2 diabetes mellitus. More precisely, it belongs to the class of biguanides, Metformin is used in the treatment of type 2 diabetes mellitus both as monotherapy and in combination therapy with other oral antidiabetic agents or with insulin, when dietary interventions and exercise are not sufficient to control the disease.
      When used in overweight diabetic patients, metformin also causes a decrease in the complications of diabetes and its use has been associated with stabilization and, albeit modest, loss of body weight. In type 2 diabetes mellitus (called also DM2 and in the past ‘adult diabetes’ or ‘food’) the insulin produced by the pancreas is unable to fully exert its action so that the body even produces it in excess, with the result on the one hand of making increasing weight and on the other hand progressively depleting the pancreas, is unable to meet the body’s needs. It is as if the body were resisting the action of insulin. Metformin reduces insulin resistance. It is taken by mouth and is the only drug useful in all stages of type 2 diabetes. It also helps improve the balance of fats and, to a limited extent, blood pressure.
      Metformin alone has important effects on blood sugar. Accompanied by physical exercise, weight loss and possibly other medications, it is often an effective therapy. It does not cause hypoglycemia, helps not to gain weight or even reduces it. The main feature of Metformin is to interact strongly with AMPK by regulating its expression. In fact, its down regulation leads to consuming ATP, synthesizing cholesterol and fatty acids and consuming glucose: a situation in which insulin levels are quite high (therefore energy abundance).On the contrary, its up regulation leads to the creation of ATP, consuming more fatty acids for energy purposes and it is a metabolic situation similar to caloric restriction in which insulin levels are kept low (therefore energy scarcity).
      Metformin by upregulating AMPK has therefore shown to have a somewhat transversal therapeutic use in the treatment of metabolic dysfunctions.
      PubDate: 2022-05-05
      DOI: 10.22158/se.v7n2p48
      Issue No: Vol. 7, No. 2 (2022)
       
 
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