Subjects -> ENVIRONMENTAL STUDIES (Total: 913 journals)
    - ENVIRONMENTAL STUDIES (810 journals)
    - POLLUTION (31 journals)
    - TOXICOLOGY AND ENVIRONMENTAL SAFETY (54 journals)
    - WASTE MANAGEMENT (18 journals)

ENVIRONMENTAL STUDIES (810 journals)                  1 2 3 4 5 | Last

Showing 1 - 200 of 378 Journals sorted alphabetically
ACS Chemical Health & Safety     Hybrid Journal   (Followers: 4)
ACS Environmental Au     Open Access   (Followers: 12)
ACS ES&T Engineering     Hybrid Journal   (Followers: 5)
Acta Brasiliensis     Open Access  
Acta Ecologica Sinica     Open Access   (Followers: 10)
Acta Oecologica     Hybrid Journal   (Followers: 12)
Advanced Electronic Materials     Hybrid Journal   (Followers: 16)
Advanced Energy and Sustainability Research     Open Access   (Followers: 8)
Advanced Membranes     Open Access   (Followers: 9)
Advanced Sustainable Systems     Hybrid Journal   (Followers: 7)
Advances in Ecological Research     Full-text available via subscription   (Followers: 47)
Advances in Environmental Chemistry     Open Access   (Followers: 17)
Advances in Environmental Sciences - International Journal of the Bioflux Society     Open Access   (Followers: 17)
Advances in Environmental Technology     Open Access   (Followers: 3)
Advances in Life Science and Technology     Open Access   (Followers: 14)
Advances in Tropical Biodiversity and Environmental Sciences     Open Access   (Followers: 5)
Aeolian Research     Hybrid Journal   (Followers: 7)
Agricultura Tecnica     Open Access   (Followers: 2)
Agricultural & Environmental Letters     Open Access   (Followers: 4)
Agro-Science     Full-text available via subscription   (Followers: 2)
Agroecological journal     Open Access   (Followers: 1)
Agronomy for Sustainable Development     Open Access   (Followers: 19)
Agrosystems, Geosciences & Environment     Open Access   (Followers: 5)
Amazon's Research and Environmental Law     Open Access   (Followers: 5)
Ambiens. Revista Iberoamericana Universitaria en Ambiente, Sociedad y Sustentabilidad     Open Access  
Ambiente & sociedade     Open Access   (Followers: 3)
American Journal of Energy and Environment     Open Access   (Followers: 6)
American Journal of Environmental Engineering     Open Access   (Followers: 6)
American Journal of Environmental Protection     Open Access   (Followers: 5)
American Journal of Environmental Sciences     Open Access   (Followers: 10)
American Naturalist     Full-text available via subscription   (Followers: 82)
Animal - Open Space     Open Access   (Followers: 6)
Annals of Civil and Environmental Engineering     Open Access   (Followers: 2)
Annals of Environmental Science and Toxicology     Open Access   (Followers: 4)
Annals of GIS     Open Access   (Followers: 31)
Annual Review of Ecology, Evolution, and Systematics     Full-text available via subscription   (Followers: 85)
Annual Review of Environment and Resources     Full-text available via subscription   (Followers: 18)
Annual Review of Pharmacology and Toxicology     Full-text available via subscription   (Followers: 27)
Annual Review of Resource Economics     Full-text available via subscription   (Followers: 13)
Applied and Environmental Soil Science     Open Access   (Followers: 14)
Applied Ecology and Environmental Sciences     Open Access   (Followers: 30)
Applied Environmental Education & Communication     Hybrid Journal   (Followers: 18)
Applied Journal of Environmental Engineering Science     Open Access   (Followers: 2)
Aquatic Ecology     Hybrid Journal   (Followers: 45)
Aquatic Toxicology     Hybrid Journal   (Followers: 26)
Arcada : Revista de conservación del patrimonio cultural     Open Access   (Followers: 1)
Architecture, Civil Engineering, Environment     Open Access   (Followers: 6)
Archives des Maladies Professionnelles et de l'Environnement     Full-text available via subscription  
Archives of Environmental and Occupational Health     Hybrid Journal   (Followers: 10)
Archives of Environmental Contamination and Toxicology     Hybrid Journal   (Followers: 12)
Archives of Environmental Protection     Open Access   (Followers: 5)
Archives of Toxicology     Hybrid Journal   (Followers: 17)
Arctic Environmental Research     Open Access  
Asian Journal of Environment & Ecology     Open Access   (Followers: 3)
Asian Journal of Rural Development     Open Access   (Followers: 10)
Asian Review of Environmental and Earth Sciences     Open Access   (Followers: 2)
ATBU Journal of Environmental Technology     Open Access   (Followers: 1)
Atmospheric and Climate Sciences     Open Access   (Followers: 37)
Atmospheric Environment     Hybrid Journal   (Followers: 71)
Atmospheric Environment : X     Open Access   (Followers: 3)
Augm Domus : Revista electrónica del Comité de Medio Ambiente de AUGM     Open Access  
Austral Ecology     Hybrid Journal   (Followers: 17)
Australasian Journal of Environmental Management     Hybrid Journal   (Followers: 9)
Australasian Journal of Human Security     Full-text available via subscription   (Followers: 2)
Australian Journal of Environmental Education     Full-text available via subscription   (Followers: 11)
Basic & Clinical Pharmacology & Toxicology     Hybrid Journal   (Followers: 11)
Basic and Applied Ecology     Hybrid Journal   (Followers: 23)
Behavioral Ecology     Hybrid Journal   (Followers: 58)
Behavioral Ecology and Sociobiology     Hybrid Journal   (Followers: 36)
Biocenosis     Open Access  
Biochar     Hybrid Journal   (Followers: 1)
Biodegradation     Hybrid Journal   (Followers: 2)
Biodiversity     Hybrid Journal   (Followers: 30)
Biofouling: The Journal of Bioadhesion and Biofilm Research     Hybrid Journal   (Followers: 2)
Bioremediation Journal     Hybrid Journal   (Followers: 4)
BioRisk     Open Access   (Followers: 2)
Boletín Semillas Ambientales     Open Access  
Bothalia : African Biodiversity & Conservation     Open Access  
Built Environment     Full-text available via subscription   (Followers: 8)
Bulletin of Environmental Contamination and Toxicology     Hybrid Journal   (Followers: 10)
Bulletin of the American Meteorological Society     Open Access   (Followers: 64)
Bumi Lestari Journal of Environment     Open Access  
Canadian Journal of Earth Sciences     Hybrid Journal   (Followers: 22)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 55)
Canadian Journal of Soil Science     Full-text available via subscription   (Followers: 12)
Canadian Water Resources Journal     Hybrid Journal   (Followers: 18)
Capitalism Nature Socialism     Hybrid Journal   (Followers: 22)
Carbon Capture Science & Technology     Open Access   (Followers: 7)
Carbon Resources Conversion     Open Access   (Followers: 2)
Case Studies in Chemical and Environmental Engineering     Open Access  
Cell Biology and Toxicology     Hybrid Journal   (Followers: 8)
Chain Reaction     Full-text available via subscription  
Challenges in Sustainability     Open Access   (Followers: 11)
Chemical Research in Toxicology     Hybrid Journal   (Followers: 20)
Chemico-Biological Interactions     Hybrid Journal   (Followers: 1)
Chemosphere     Hybrid Journal   (Followers: 19)
Child and Adolescent Mental Health     Hybrid Journal   (Followers: 72)
Chinese Journal of Environmental Law     Hybrid Journal   (Followers: 2)
Ciencia, Ambiente y Clima     Open Access   (Followers: 1)
City and Environment Interactions     Open Access   (Followers: 3)
Civil and Environmental Engineering     Open Access   (Followers: 7)
Civil and Environmental Engineering Reports     Open Access   (Followers: 4)
Civil and Environmental Research     Open Access   (Followers: 14)
CLEAN - Soil, Air, Water     Hybrid Journal   (Followers: 19)
Clean Technologies     Open Access   (Followers: 1)
Clean Technologies and Environmental Policy     Hybrid Journal   (Followers: 5)
Cleaner and Circular Bioeconomy (CLCB)     Open Access   (Followers: 6)
Cleaner Energy Systems     Open Access   (Followers: 3)
Cleaner Environmental Systems     Open Access   (Followers: 1)
Cleaner Production Letters     Hybrid Journal   (Followers: 1)
Cleaner Waste Systems     Open Access   (Followers: 2)
Cleanroom Technology     Full-text available via subscription   (Followers: 1)
Climate and Energy     Full-text available via subscription   (Followers: 12)
Climate Change Ecology     Open Access   (Followers: 30)
Climate Change Economics     Hybrid Journal   (Followers: 52)
Climate Policy     Hybrid Journal   (Followers: 60)
Climate Resilience and Sustainability     Open Access   (Followers: 35)
Coastal Engineering Journal     Hybrid Journal   (Followers: 9)
Cogent Environmental Science     Open Access  
Columbia Journal of Environmental Law     Open Access   (Followers: 15)
Computational Ecology and Software     Open Access   (Followers: 9)
Computational Water, Energy, and Environmental Engineering     Open Access   (Followers: 6)
Conservation and Society     Open Access   (Followers: 14)
Conservation Letters     Open Access   (Followers: 52)
Conservation Science     Open Access   (Followers: 28)
Consilience : The Journal of Sustainable Development     Open Access   (Followers: 2)
Contemporary Problems of Ecology     Hybrid Journal   (Followers: 4)
Critical Reviews in Environmental Science and Technology     Hybrid Journal   (Followers: 10)
Critical Reviews in Toxicology     Hybrid Journal   (Followers: 22)
Cuadernos de Investigación Geográfica / Geographical Research Letters     Open Access  
Culture, Agriculture, Food and Environment     Hybrid Journal   (Followers: 24)
Culture, Agriculture, Food and Environment     Hybrid Journal   (Followers: 8)
Current Environmental Health Reports     Hybrid Journal   (Followers: 2)
Current Forestry Reports     Hybrid Journal   (Followers: 1)
Current Landscape Ecology Reports     Hybrid Journal   (Followers: 3)
Current Opinion in Environmental Science & Health     Hybrid Journal  
Current Opinion in Environmental Sustainability     Hybrid Journal   (Followers: 14)
Current Research in Ecological and Social Psychology     Open Access   (Followers: 7)
Current Research in Environmental Sustainability     Open Access   (Followers: 5)
Current Research in Green and Sustainable Chemistry     Open Access   (Followers: 1)
Current Research in Microbiology     Open Access   (Followers: 20)
Current Sustainable/Renewable Energy Reports     Hybrid Journal   (Followers: 7)
Die Bodenkultur : Journal of Land Management, Food and Environment     Open Access  
Disaster Prevention and Management     Hybrid Journal   (Followers: 27)
Discover Sustainability     Open Access   (Followers: 5)
disP - The Planning Review     Hybrid Journal   (Followers: 1)
Drug and Chemical Toxicology     Hybrid Journal   (Followers: 12)
Duke Environmental Law & Policy Forum     Open Access   (Followers: 9)
E3S Web of Conferences     Open Access  
Earth and Environmental Science Transactions of the Royal Society of Edinburgh     Hybrid Journal   (Followers: 7)
Earth Interactions     Open Access   (Followers: 10)
Earth Science Informatics     Hybrid Journal   (Followers: 6)
Earth System Governance     Open Access   (Followers: 4)
Earth System Science Data (ESSD)     Open Access   (Followers: 7)
Earth Systems and Environment     Hybrid Journal   (Followers: 4)
Earthquake Science     Hybrid Journal   (Followers: 11)
EchoGéo     Open Access  
Eco-Environment & Health     Open Access   (Followers: 6)
Eco-Thinking     Open Access   (Followers: 4)
Ecocycles     Open Access   (Followers: 4)
Ecohydrology     Hybrid Journal   (Followers: 13)
Ecohydrology & Hydrobiology     Full-text available via subscription   (Followers: 5)
Ecologia Aplicada     Open Access  
Ecología en Bolivia     Open Access  
Ecological Applications     Full-text available via subscription   (Followers: 205)
Ecological Chemistry and Engineering S     Open Access   (Followers: 4)
Ecological Complexity     Hybrid Journal   (Followers: 8)
Ecological Engineering     Hybrid Journal   (Followers: 7)
Ecological Indicators     Hybrid Journal   (Followers: 22)
Ecological Informatics     Hybrid Journal   (Followers: 4)
Ecological Management & Restoration     Hybrid Journal   (Followers: 17)
Ecological Modelling     Hybrid Journal   (Followers: 74)
Ecological Monographs     Full-text available via subscription   (Followers: 38)
Ecological Processes     Open Access   (Followers: 2)
Ecological Questions     Open Access   (Followers: 5)
Ecological Research     Hybrid Journal   (Followers: 10)
Ecological Restoration     Full-text available via subscription   (Followers: 25)
Ecologist, The     Full-text available via subscription   (Followers: 23)
Ecology     Full-text available via subscription   (Followers: 425)
Ecology and Evolution     Open Access   (Followers: 106)
Ecology Letters     Hybrid Journal   (Followers: 285)
EcoMat : Functional Materials for Green Energy and Environment     Open Access  
Economics and Policy of Energy and the Environment     Full-text available via subscription   (Followers: 16)
Economics of Energy & Environmental Policy     Hybrid Journal   (Followers: 3)
Économie rurale     Open Access   (Followers: 3)
Ecoprint : An International Journal of Ecology     Open Access   (Followers: 4)
Ecopsychology     Hybrid Journal   (Followers: 7)
Ecosphere     Open Access   (Followers: 12)
Ecosystem Services     Hybrid Journal   (Followers: 8)
Ecosystems     Hybrid Journal   (Followers: 33)
Ecosystems and People     Open Access   (Followers: 4)
Ecotoxicology     Hybrid Journal   (Followers: 8)
Ecotoxicology and Environmental Safety     Hybrid Journal   (Followers: 10)
Ecotrophic : Journal of Environmental Science     Open Access  
Ecozon@ : European Journal of Literature, Culture and Environment     Open Access   (Followers: 3)
Éducation relative à l'environnement     Open Access  
Electronic Green Journal     Open Access   (Followers: 4)
Empowering Sustainability International Journal     Open Access   (Followers: 4)
Energy & Environment     Hybrid Journal   (Followers: 25)
Energy & Environmental Science     Hybrid Journal   (Followers: 37)

        1 2 3 4 5 | Last

Similar Journals
Journal Cover
Cell Biology and Toxicology
Journal Prestige (SJR): 0.924
Citation Impact (citeScore): 5
Number of Followers: 8  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1573-6822 - ISSN (Online) 0742-2091
Published by Springer-Verlag Homepage  [2468 journals]
  • Retraction Note: FoxM1-mediated RFC5 expression promotes temozolomide
           resistance

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      PubDate: 2024-06-08
       
  • The microRNA Let-7 and its exosomal form: Epigenetic regulators of
           gynecological cancers

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      Abstract: Many types of gynecological cancer (GC) are often silent until they reach an advanced stage, and are therefore often diagnosed too late for effective treatment. Hence, there is a real need for more efficient diagnosis and treatment for patients with GC. During recent years, researchers have increasingly studied the impact of microRNAs cancer development, leading to a number of applications in detection and treatment. MicroRNAs are a particular group of tiny RNA molecules that regulate regular gene expression by affecting the translation process. The downregulation of numerous miRNAs has been observed in human malignancies. Let-7 is an example of a miRNA that controls cellular processes as well as signaling cascades to affect post-transcriptional gene expression. Recent research supports the hypothesis that enhancing let-7 expression in those cancers where it is downregulated may be a potential treatment option. Exosomes are tiny vesicles that move through body fluids and can include components like miRNAs (including let-7) that are important for communication between cells. Studies proved that exosomes are able to enhance tumor growth, angiogenesis, chemoresistance, metastasis, and immune evasion, thus suggesting their importance in GC management. Graphical Impact of let-7 on female malignancies and diseases of the female reproductive tract. Let-7 expression is dysregulated in a variety of gynaecological and obstetric disorders.
      PubDate: 2024-06-05
       
  • Deoxynivalenol induces m6A-mediated upregulation of p21 and growth arrest
           of mouse hippocampal neuron cells in vitro

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      Abstract: Hippocampal neurons maintain the ability of proliferation throughout life to support neurogenesis. Deoxynivalenol (DON) is a mycotoxin that exhibits brain toxicity, yet whether and how DON affects hippocampal neurogenesis remains unknown. Here, we use mouse hippocampal neuron cells (HT-22) as a model to illustrate the effects of DON on neuron proliferation and to explore underlying mechanisms. DON exposure significantly inhibits the proliferation of HT-22 cells, which is associated with an up-regulation of cell cycle inhibitor p21 at both mRNA and protein levels. Global and site-specific m6A methylation levels on the 3’UTR of p21 mRNA are significantly increased in response to DON treatment, whereas inhibition of m6A hypermethylation significantly alleviates DON-induced cell cycle arrest. Further mechanistic studies indicate that the m6A readers YTHDF1 and IGF2BP1 are responsible for m6A-mediated increase in p21 mRNA stability. Meanwhile, 3’UTR of E3 ubiquitin ligase TRIM21 mRNA is also m6A hypermethylated, and another m6A reader YTHDF2 binds to the m6A sites, leading to decreased TRIM21 mRNA stability. Consequently, TRIM21 suppression impairs ubiquitin-mediated p21 protein degradation. Taken together, m6A-mediated upregulation of p21, at both post-transcriptional and post-translational levels, contributes to DON-induced inhibition of hippocampal neuron proliferation. These results may provide new insights for epigenetic therapy of neurodegenerative diseases. Graphical abstract DON inhibits the proliferation of HT-22 cells. RNA m6A hypermethylation on the transcript of p21 enhances the mRNA stability in a YTHDF1- and IGF2BP1-dependent manner, which leads to the upregulation of p21. RNA m6A hypermethylation on the transcript of TRIM21 decreases the mRNA stability in a YTHDF2-dependent manner, which contributes to prevent p21 ubiquitin-mediated degradation. High expression of p21 contributes to inhibit cell proliferation.
      PubDate: 2024-06-04
       
  • Downregulation of MYBL1 in endothelial cells contributes to
           atherosclerosis by repressing PLEKHM1-inducing autophagy

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      Abstract: MYBL1 is a strong transcriptional activator involved in the cell signaling. However, there is no systematic study on the role of MYBL1 in atherosclerosis. The aim of this study is to elucidate the role and mechanism of MYBL1 in atherosclerosis. GSE28829, GSE43292 and GSE41571 were downloaded from NCBI for differentially expressed analysis. The expression levels of MYBL1 in atherosclerotic plaque tissue and normal vessels were detected by qRT-PCR, Western blot and Immunohistochemistry. Transwell and CCK-8 were used to detect the migration and proliferation of HUVECs after silencing MYBL1. RNA-seq, Western blot, qRT-PCR, Luciferase reporter system, Immunofluorescence, Flow cytometry, ChIP and CO-IP were used to study the role and mechanism of MYBL1 in atherosclerosis. The microarray data of GSE28829, GSE43292, and GSE41571 were analyzed and intersected, and then MYBL1 were verified. MYBL1 was down-regulated in atherosclerotic plaque tissue. After silencing of MYBL1, HUVECs were damaged, and their migration and proliferation abilities were weakened. Overexpression of MYBL1 significantly enhanced the migration and proliferation of HUVECs. MYBL1 knockdown induced abnormal autophagy in HUVEC cells, suggesting that MYBL1 was involved in the regulation of HUVECs through autophagy. Mechanistic studies showed that MYBL1 knockdown inhibited autophagosome and lysosomal fusion in HUVECs by inhibiting PLEKHM1, thereby exacerbating atherosclerosis. Furthermore, MYBL1 was found to repress lipid accumulation in HUVECs after oxLDL treatment. MYBL1 knockdown in HUVECs was involved in atherosclerosis by inhibiting PLEKHM1-induced autophagy, which provided a novel target of therapy for atherosclerosis. Graphical abstract
      PubDate: 2024-05-27
       
  • Exosomes derived from adipose tissue-derived stem cells alleviated
           H2O2-induced oxidative stress and endothelial-to-mesenchymal transition in
           human umbilical vein endothelial cells by inhibition of the
           mir-486-3p/Sirt6/Smad signaling pathway

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      Abstract: Hypertrophic scar (HS) is characterized by excessive collagen deposition and myofibroblasts activation. Endothelial-to-mesenchymal transition (EndoMT) and oxidative stress were pivotal in skin fibrosis process. Exosomes derived from adipose tissue-derived stem cells (ADSC-Exo) have the potential to attenuate EndoMT and inhibit fibrosis. The study revealed reactive oxygen species (ROS) levels were increased during EndoMT occurrence of dermal vasculature of HS. The morphology of endothelial cells exposure to H2O2, serving as an in vitro model of oxidative stress damage, transitioned from a cobblestone-like appearance to a spindle-like shape. Additionally, the levels of endothelial markers decreased in H2O2-treated endothelial cell, while the expression of fibrotic markers increased. Furthermore, H2O2 facilitated the accumulation of ROS, inhibited cell proliferation, retarded its migration and suppressed tube formation in endothelial cell. However, ADSC-Exo counteracted the biological effects induced by H2O2. Subsequently, miRNAs sequencing analysis revealed the significance of mir-486-3p in endothelial cell exposed to H2O2 and ADSC-Exo. Mir-486-3p overexpression enhanced the acceleration of EndoMT, its inhibitors represented the attenuation of EndoMT. Meanwhile, the target regulatory relationship was observed between mir-486-3p and Sirt6, whereby Sirt6 exerted its anti-EndoMT effect through Smad2/3 signaling pathway. Besides, our research had successfully demonstrated the impact of ADSC-Exo and mir-486-3p on animal models. These findings of our study collectively elucidated that ADSC-Exo effectively alleviated H2O2-induced ROS and EndoMT by inhibiting the mir-486-3p/Sirt6/Smad axis. Graphical A schematic diagram summarizing the impact of ADSC-Exo on oxidative stress and endothelial-to-mesenchymal transition in endothelial cells was presented in this study. ADSC-Exo effectively alleviated the accumulation of ROS in endothelial cells induced by H2O2 and suppressed the pro-fibrotic function through modulation of the mir-486-3p/Sirt6/Smad signaling pathway. ADSC-Exo attenuated the up-regulation of mir-486-3p in endothelial cells exposure to H2O2, establishing a target relationship between mir-486-3p and Sirt6. Overexpression of Sirt6 inhibited the occurrence of endothelial-to-mesenchymal transition, thereby suppressing collagen deposition and myofibroblasts activity by the regulation of Smad2/3 phosphorylation. Consequently, this led to a reduction in hypertrophic scar formation. Graphical Highlights 1. The occurrence and development of ROS and endothelial-to-mesenchymal transition promoted hypertrophic scar fibrosis; 2. H2O2 induced oxidative stress and EndoMT of endothelial cells, whereas ADSC-Exo ameliorated the process; 3. Mir-486-3p was crucial for H2O2-induced EndoMT and the improvement of ADSC-Exo; 4. Mir-486-3p directly targeted Sirt6 to facilitate EndoMT by regulating Smad signaling pathway.
      PubDate: 2024-05-25
       
  • Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional
           regulation of TXNIP

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      Abstract: Ensartinib, an approved ALK inhibitor, is used as a first-line therapy for advanced ALK-positive non-small cell lung cancer in China. However, the hepatotoxicity of ensartinib seriously limits its clinical application and the regulatory mechanism is still elusive. Here, through transcriptome analysis we found that transcriptional activation of TXNIP was the main cause of ensartinib-induced liver dysfunction. A high TXNIP level and abnormal TXNIP translocation severely impaired hepatic function via mitochondrial dysfunction and hepatocyte apoptosis, and TXNIP deficiency attenuated hepatocyte apoptosis under ensartinib treatment. The increase in TXNIP induced by ensartinib is related to AKT inhibition and is mediated by MondoA. Through screening potential TXNIP inhibitors, we found that the natural polyphenolic flavonoid rutin, unlike most reported TXNIP inhibitors can inhibit TXNIP by binding to TXNIP and partially promoting its proteasomal degradation. Further studies showed rutin can attenuate the hepatotoxicity of ensartinib without antagonizing its antitumor effects. Accordingly, we suggest that TXNIP is the key cause of ensartinib-induced hepatotoxicity and rutin is a potential clinically safe and feasible therapeutic strategy for TXNIP intervention. Graphical
      PubDate: 2024-05-24
       
  • Distinct epigenetic modulation of differentially expressed genes in the
           adult mouse brain following prenatal exposure to low-dose bisphenol A

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      Abstract: Bisphenol A (BPA) is a common component in the manufacture of daily plastic consumer goods. Recent studies have suggested that prenatal exposure to BPA can increase the susceptibility of offspring to mental illness, although the underlying mechanisms remain unclear. In this study, we performed transcriptomic and epigenomic profiling in the adult mouse brain following prenatal exposure to low-dose BPA. We observed a sex-specific transcriptional dysregulation in the cortex, with more significant differentially expressed genes was observed in adult cortex from male offspring. Moreover, the upregulated genes primarily influenced neuronal functions, while the downregulated genes were significantly associated with energy metabolism pathways. More evidence supporting impaired mitochondrial function included a decreased ATP level and a reduced number of mitochondria in the cortical neuron of the BPA group. We further investigated the higher-order chromatin regulatory patterns of DEGs by incorporating published Hi-C data. Interestingly, we found that upregulated genes exhibited more distal interactions with multiple enhancers, while downregulated genes displayed relatively short-range interactions among adjacent genes. Our data further revealed decreased H3K9me3 signal on the distal enhancers of upregulated genes, whereas increased DNA methylation and H3K27me3 signals on the promoters of downregulated genes. In summary, our study provides compelling evidence for the potential health risks associated with prenatal exposure to BPA, and uncovers sex-specific transcriptional changes with a complex interplay of multiple epigenetic mechanisms. Graphical abstract 1. Distinct chromatin interaction pattern of DEGs in the cortex of adult male offspring in response to prenatal BPA exposure. 2. Upregulated genes exhibited intensive and long-range chromatin interactions, with decreased H3K9me3 modification on the distal enhancers. 3. Downregulated genes were featured by promoter-promoter interactions among adjacent genes and increased DNA methylation and H3K27me3 modification at the promoter regions.
      PubDate: 2024-05-22
       
  • Mild endoplasmic reticulum stress alleviates FB1-triggered intestinal
           pyroptosis via the Sec62-PERK pathway

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      Abstract: Fumonisin B1 (FB1), a water-soluble mycotoxin released by Fusarium moniliforme Sheld, is widely present in corn and its derivative products, and seriously endangers human life and health. Recent studies have reported that FB1 can lead to pyroptosis, however, the mechanisms by which FB1-induced pyroptosis remain indistinct. In the present study, we aim to investigate the mechanisms of pyroptosis in intestinal porcine epithelial cells (IPEC-J2) and the relationship between FB1-induced endoplasmic reticulum stress (ERS) and pyroptosis. Our experimental results showed that the pyroptosis protein indicators in IPEC-J2 were significantly increased after exposure to FB1. The ERS markers, including glucose-regulated Protein 78 (GRP78), PKR-like ER kinase protein (PERK), and preprotein translocation factor (Sec62) were also significantly increased. Using small interfering RNA silencing of PERK or Sec62, the results demonstrated that upregulation of Sec62 activates the PERK pathway, and activation of the PERK signaling pathway is upstream of FB1-induced pyroptosis. After using the ERS inhibitor 4-PBA reduced the FB1-triggered intestinal injury by the Sec62-PERK pathway. In conclusion, we found that FB1 induced pyroptosis by upregulating Sec62 to activate the PERK pathway, and mild ERS alleviates FB1-triggered damage. It all boils down to one fact, the study provides a new perspective for further, and improving the toxicological mechanism of FB1. Graphical
      PubDate: 2024-05-21
       
  • Deficiency of P2RY11 causes narcolepsy and attenuates the recruitment of
           neutrophils and macrophages in the inflammatory response in zebrafish

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      Abstract: Purinergic receptor P2Y11, a G protein-coupled receptor that is stimulated by extracellular ATP, has been demonstrated to be related to the chemotaxis of granulocytes, apoptosis of neutrophils, and secretion of cytokines in vitro. P2Y11 mutations were associated with narcolepsy. However, little is known about the roles of P2RY11 in the occurrence of narcolepsy and inflammatory response in vivo. In this study, we generated a zebrafish P2Y11 mutant using CRISPR/Cas9 genome editing and demonstrated that the P2Y11 mutant replicated the narcolepsy-like features including reduced HCRT expression and excessive daytime sleepiness, suggesting that P2Y11 is essential for HCRT expression. Furthermore, we accessed the cytokine expression in the mutant and revealed that the P2RY11 mutation disrupted the systemic inflammatory balance by reducing il4, il10 and tgfb, and increasing il6, tnfa, and il1b. In addition, the P2RY11-deficient larvae with caudal fin injuries exhibited significantly slower migration and less recruitment of neutrophils and macrophages at damaged site, and lower expression of anti-inflammatory cytokines during tissue damage. All these findings highlight the vital roles of P2RY11 in maintaining HCRT production and secreting anti-inflammatory cytokines in the native environment, and suggested that P2RY11-deficient zebrafish can serve as a reliable and unique model to further explore narcolepsy and inflammatory-related diseases with impaired neutrophil and macrophage responses. Graphical abstract
      PubDate: 2024-05-21
       
  • Spatial transcriptomics reveals gene interactions and signaling pathway
           dynamics in rat embryos with anorectal malformation

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      Abstract: Abstract Anorectal malformation (ARM) is a prevalent early pregnancy digestive tract anomaly. The intricate anatomy of the embryonic cloaca region makes it challenging for traditional high-throughput sequencing methods to capture location-specific information. Spatial transcriptomics was used to sequence libraries of frozen sections from embryonic rats at gestational days (GD) 14 to 16, covering both normal and ARM cases. Bioinformatics analyses and predictions were performed using methods such as WGCNA, GSEA, and PROGENy. Immunofluorescence staining was used to verify gene expression levels. Gene expression data was obtained with anatomical annotations of clusters, focusing on the cloaca region's location-specific traits. WGCNA revealed gene modules linked to normal and ARM cloacal anatomy development, with cooperation between modules on GD14 and GD15. Differential gene expression profiles and functional enrichment were presented. Notably, protein levels of Pcsk9, Hmgb2, and Sod1 were found to be downregulated in the GD15 ARM hindgut. The PROGENy algorithm predicted the activity and interplay of common signaling pathways in embryonic sections, highlighting their synergistic and complementary effects. A competing endogenous RNA (ceRNA) regulatory network was constructed from whole transcriptome data. Spatial transcriptomics provided location-specific cloaca region gene expression. Diverse bioinformatics analyses deepened our understanding of ARM's molecular interactions, guiding future research and providing insights into gene regulation in ARM development.
      PubDate: 2024-05-21
       
  • Activation of lipophagy ameliorates cadmium-induced neural tube defects
           via reducing low density lipoprotein cholesterol levels in mouse placentas
           

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      Abstract: Abstract Neural tube defects (NTDs) represent a prevalent and severe category of congenital anomalies in humans. Cadmium (Cd) is an environmental teratogen known to cause fetal NTDs. However, its underlying mechanisms remain elusive. This study aims to investigate the therapeutic potential of lipophagy in the treatment of NTDs, providing valuable insights for future strategies targeting lipophagy activation as a means to mitigate NTDs.We successfully modeled NTDs by Cd exposure during pregnancy. RNA sequencing was employed to investigate the transcriptomic alterations and functional enrichment of differentially expressed genes in NTD placental tissues. Subsequently, pharmacological/genetic (Atg5-/- placentas) experiments confirmed that inducing placental lipophagy can alleviate Cd induced-NTDs. We found that Cd exposure caused NTDs. Further analyzed transcriptomic data from the placentas with NTDs which revealed significant downregulation of low-density lipoprotein receptor associated protein 1(Lrp1) gene expression responsible for positive regulation of low-density lipoprotein cholesterol (LDL-C) transport. Correspondingly, there was an increase in maternal serum/placenta/amniotic fluid LDL-C content. Subsequently, we have discovered that Cd exposure activated placental lipophagy. Pharmacological/genetic (Atg5-/- placentas) experiments confirmed that inducing placental lipophagy can alleviate Cd induced-NTDs. Furthermore, our findings demonstrate that activation of placental lipophagy effectively counteracts the Cd-induced elevation in LDL-C levels. Lipophagy serves to mitigate Cd-induced NTDs by reducing LDL-C levels within mouse placentas.
      PubDate: 2024-05-21
       
  • SIRT1 restores mitochondrial structure and function in rats by activating
           SIRT3 after cerebral ischemia/reperfusion injury

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      Abstract: Mitochondrial dysfunction contributes to cerebral ischemia–reperfusion (CI/R) injury, which can be ameliorated by Sirtuin-3 (SIRT3). Under stress conditions, the SIRT3-promoted mitochondrial functional recovery depends on both its activity and expression. However, the approach to enhance SIRT3 activity after CI/R injury remains unelucidated. In this study, Sprague–Dawley (SD) rats were intracranially injected with either adeno-associated viral Sirtuin-1 (AAV-SIRT1) or AAV-sh_SIRT1 before undergoing transient middle cerebral artery occlusion (tMCAO). Primary cortical neurons were cultured and transfected with lentiviral SIRT1 (LV-SIRT1) and LV-sh_SIRT1 respectively before oxygen–glucose deprivation/reoxygenation (OGD/R). Afterwards, rats and neurons were respectively treated with a selective SIRT3 inhibitor, 3-(1H-1,2,3-triazol-4-yl) pyridine (3-TYP). The expression, function, and related mechanism of SIRT1 were investigated by Western Blot, flow cytometry, immunofluorescence staining, etc. After CI/R injury, SIRT1 expression decreased in vivo and in vitro. The simulation and immune-analyses reported strong interaction between SIRT1 and SIRT3 in the cerebral mitochondria before and after CI/R. SIRT1 overexpression enhanced SIRT3 activity by increasing the deacetylation of SIRT3, which ameliorated CI/R-induced cerebral infarction, neuronal apoptosis, oxidative stress, neurological and motor dysfunction, and mitochondrial respiratory chain dysfunction, promoted mitochondrial biogenesis, and retained mitochondrial integrity and mitochondrial morphology. Meanwhile, SIRT1 overexpression alleviated OGD/R-induced neuronal death and mitochondrial bioenergetic deficits. These effects were reversed by AAV-sh_SIRT1 and the neuroprotective effects of SIRT1 were partially offset by 3-TYP. These results suggest that SIRT1 restores the structure and function of mitochondria by activating SIRT3, offering neuroprotection against CI/R injury, which signifies a potential approach for the clinical management of cerebral ischemia. Graphical 1. SIRT1 is downregulated after cerebral ischemia/reperfusion injury. 2. SIRT1 can increase the deacetylation of SIRT3 and enhance the activity of SIRT3 after cerebral ischemia/reperfusion injury. 3. SIRT1 enhances the mitochondrial structure repair and functional recovery by activating SIRT3 after cerebral ischemia/reperfusion injury in rats, thereby promoting neurological function.
      PubDate: 2024-05-20
       
  • Exosomes enriched by miR-429-3p derived from ITGB1 modified Telocytes
           alleviates hypoxia-induced pulmonary arterial hypertension through
           regulating Rac1 expression

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      Abstract: Background Recent studies have emphasized the critical role of Telocytes (TCs)-derived exosomes in organ tissue injury and repair. Our previous research showed a significant increase in ITGB1 within TCs. Pulmonary Arterial Hypertension (PAH) is marked by a loss of microvessel regeneration and progressive vascular remodeling. This study aims to investigate whether exosomes derived from ITGB1-modified TCs (ITGB1-Exo) could mitigate PAH. Methods We analyzed differentially expressed microRNAs (DEmiRs) in TCs using Affymetrix Genechip miRNA 4.0 arrays. Exosomes isolated from TC culture supernatants were verified through transmission electron microscopy and Nanoparticle Tracking Analysis. The impact of miR-429-3p-enriched exosomes (Exo-ITGB1) on hypoxia-induced pulmonary arterial smooth muscle cells (PASMCs) was evaluated using CCK-8, transwell assay, and inflammatory factor analysis. A four-week hypoxia-induced mouse model of PAH was constructed, and H&E staining, along with Immunofluorescence staining, were employed to assess PAH progression. Results Forty-five miRNAs exhibited significant differential expression in TCs following ITGB1 knockdown. Mus-miR-429-3p, significantly upregulated in ITGB1-overexpressing TCs and in ITGB1-modified TC-derived exosomes, was selected for further investigation. Exo-ITGB1 notably inhibited the migration, proliferation, and inflammation of PASMCs by targeting Rac1. Overexpressing Rac1 partly counteracted Exo-ITGB1’s effects. In vivo administration of Exo-ITGB1 effectively reduced pulmonary vascular remodeling and inflammation. Conclusions Our findings reveal that ITGB1-modified TC-derived exosomes exert anti-inflammatory effects and reverse vascular remodeling through the miR-429-3p/Rac1 axis. This provides potential therapeutic strategies for PAH treatment. Graphical 1. Identification of Differentially Expressed microRNAs (DEmiRs) in ITGB1 overexpressed TCs. 2. Effects of Exo-ITGB1 or miR-429-3p on Hypoxia-Induced PASMCs in vitro. 3. Exo-ITGB1 inhibits the hyper-proliferation and migration of PASMCs through regulating miR-429-3p/Rac1 axis in vitro. 4. The therapeutic potential of Exo-ITGB1 in hypoxia-induced PAH model in vivo.
      PubDate: 2024-05-20
       
  • MKLN1-AS promotes pancreatic cancer progression as a crucial downstream
           mediator of HIF-1α through miR-185-5p/TEAD1 pathway

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      Abstract: In pancreatic ductal adenocarcinomas (PDAC), profound hypoxia plays key roles in regulating cancer cell behavior, including proliferation, migration, and resistance to therapies. The initial part of this research highlights the important role played by long noncoding RNA (lncRNA) MKLN1-AS, which is controlled by hypoxia-inducible factor-1 alpha (HIF-1α), in the progression of PDAC. Human samples of PDAC showed a notable increase in MKLN1-AS expression, which was linked to a worse outcome. Forced expression of MKLN1-AS greatly reduced the inhibitory impact on the growth and spread of PDAC cells caused by HIF-1α depletion. Experiments on mechanisms showed that HIF-1α influences the expression of MKLN1-AS by directly attaching to a hypoxia response element in the promoter region of MKLN1-AS.MKLN1-AS acts as a competitive endogenous RNA (ceRNA) by binding to miR-185-5p, resulting in the regulation of TEAD1 expression and promoting cell proliferation, migration, and tumor growth. TEAD1 subsequently enhances the development of PDAC. Our study results suggest that MKLN1-AS could serve as a promising target for treatment and a valuable indicator for predicting outcomes in PDAC. PDAC is associated with low oxygen levels, and the long non-coding RNA MKLN1-AS interacts with TEAD1 in this context. Graphical abstract
      PubDate: 2024-05-13
       
  • Exosomal YB-1 facilitates ovarian restoration by MALAT1/miR-211-5p/FOXO3
           axis

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      Abstract: Abstract Premature ovarian failure (POF) affects many adult women less than 40 years of age and leads to infertility. Mesenchymal stem cells-derived small extracellular vesicles (MSCs-sEVs) are attractive candidates for ovarian function restoration and folliculogenesis for POF due to their safety and efficacy, however, the key mediator in MSCs-sEVs that modulates this response and underlying mechanisms remains elusive. Herein, we reported that YB-1 protein was markedly downregulated in vitro and in vivo models of POF induced with H2O2 and CTX respectively, accompanied by granulosa cells (GCs) senescence phenotype. Notably, BMSCs-sEVs transplantation upregulated YB-1, attenuated oxidative damage-induced cellular senescence in GCs, and significantly improved the ovarian function of POF rats, but that was reversed by YB-1 depletion. Moreover, YB-1 showed an obvious decline in serum and GCs in POF patients. Mechanistically, YB-1 as an RNA-binding protein (RBP) physically interacted with a long non-coding RNA, MALAT1, and increased its stability, further, MALAT1 acted as a competing endogenous RNA (ceRNA) to elevate FOXO3 levels by sequestering miR-211-5p to prevent its degradation, leading to repair of ovarian function. In summary, we demonstrated that BMSCs-sEVs improve ovarian function by releasing YB-1, which mediates MALAT1/miR-211-5p/FOXO3 axis regulation, providing a possible therapeutic target for patients with POF.
      PubDate: 2024-05-03
       
  • Function and regulation of Rab GTPases in cancers

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      Abstract: The Rab small GTPases are characterized by the distinct intracellular localization and modulate various endocytic, transcytic and exocytic transport pathways. Rab proteins function as scaffolds that connect signaling pathways and intracellular membrane trafficking processes through the recruitment of effectors, such as tethering factors, phosphatases, motors and kinases. In different cancers, Rabs play as either an onco-protein or a tumor suppressor role, highly dependending on the context. The molecular mechanistic research has revealed that Rab proteins are involved in cancer progression through influences on migration, invasion, metabolism, exosome secretion, autophagy, and drug resistance of cancer cells. Therefore, targeting Rab GTPases to recover the dysregulated vesicle transport systems may provide potential strategy to restrain cancer progression. In this review, we discuss the regulation of Rab protein level and activity in modulating pathways involved in tumor progression, and propose that Rab proteins may serve as a prognostic factor in different cancers. Graphical • Rab GTPases together with the cognate effectors coordinates the dynamics of trafficking pathway and ensures the spatiotemporal regulation of vesicle trafficking. • Functional impairments of the regulatory network of vesicle trafficking are associated with tumorigenesis. • Rab proteins play oncogenic or tumor suppressor roles in different cancers depending on context.
      PubDate: 2024-05-02
       
  • Exosomes as mediators of signal transmitters in biotoxins toxicity: a
           comprehensive review

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      Abstract: Small membranes known as exosomes surround them and are released by several cell types both in vitro and in vivo. These membranes are packed with a variety of biomolecules, including proteins, lipids, deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and non-coding RNA (ncRNA). As a source of biological nanomaterials, exosomes play a role in information and substance transmission between cells and have been identified as a general method of facilitating communication during interactions between the body, target organs, and toxins.. In order to understand the changes and mechanism of the composition and level of exosomes after biotoxin infection, this review focuses on current findings on the exosomes and highlights their novel uses in the toxicity mechanism. Exosomes are mainly used as a delivery carrier or mediated by receptors, and play an immune role after the toxin enters the body. This review expounds on the importance of exosomes in the toxicological mechanism of biotoxins and provides new insights for further diagnosis of toxic biomarkers, detoxification, and treatment development. Graphical abstract
      PubDate: 2024-05-02
       
  • Integration of clinical phenoms and metabolomics facilitates precision
           medicine for lung cancer

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      Abstract: Lung cancer is a common malignancy that is frequently associated with systemic metabolic disorders. Early detection is pivotal to survival improvement. Although blood biomarkers have been used in its early diagnosis, missed diagnosis and misdiagnosis still exist due to the heterogeneity of lung cancer. Integration of multiple biomarkers or trans-omics results can improve the accuracy and reliability for lung cancer diagnosis. As metabolic reprogramming is a hallmark of lung cancer, metabolites, specifically lipids might be useful for lung cancer detection, yet systematic characterizations of metabolites in lung cancer are still incipient. The present study profiled the polar metabolome and lipidome in the plasma of lung cancer patients to construct an inclusive metabolomic atlas of lung cancer. A comprehensive analysis of lung cancer was also conducted combining metabolomics with clinical phenotypes. Furthermore, the differences in plasma lipid metabolites were compared and analyzed among different lung cancer subtypes. Alcohols, amides, and peptide metabolites were significantly increased in lung cancer, while carboxylic acids, hydrocarbons, and fatty acids were remarkably decreased. Lipid profiling revealed a significant increase in plasma levels of CER, PE, SM, and TAG in individuals with lung cancer as compared to those in healthy controls. Correlation analysis confirmed the association between a panel of metabolites and TAGs. Clinical trans-omics studies elucidated the complex correlations between lipidomic data and clinical phenotypes. The present study emphasized the clinical importance of lipidomics in lung cancer, which involves the correlation between metabolites and the expressions of other omics, ultimately influencing clinical phenotypes. This novel trans-omics network approach would facilitate the development of precision therapy for lung cancer. Graphical 1. Integrating multiple biomarkers or trans-omics results improves diagnostic accuracy and reliability in heterogeneous lung cancer. 2. Metabolomics and lipidomics, along with clinical phenotypes, construct a comprehensive metabolic profile of lung cancer patients. 3. TAG expression shows strong positive correlation with polar metabolites, potentially impacting clinical phenotypic changes in lung cancer patients.
      PubDate: 2024-05-01
       
  • Retinoic acid mitigates the NSC319726-induced spermatogenesis dysfunction
           through cuproptosis-independent mechanisms

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      Abstract: Abstract Copper ionophore NSC319726 has attracted researchers' attention in treating diseases, particularly cancers. However, its potential effects on male reproduction during medication are unclear. This study aimed to determine whether NSC319726 exposure affected the male reproductive system. The reproductive toxicity of NSC319726 was evaluated in male mice following a continuous exposure period of 5 weeks. The result showed that NSC319726 exposure caused testis index reduction, spermatogenesis dysfunction, and architectural damage in the testis and epididymis. The exposure interfered with spermatogonia proliferation, meiosis initiation, sperm count, and sperm morphology. The exposure also disturbed androgen synthesis and blood testis barrier integrity. NSC319726 treatment could elevate the copper ions in the testis to induce cuproptosis in the testis. Copper chelator rescued the elevated copper ions in the testis and partly restored the spermatogenesis dysfunction caused by NSC319726. NSC319726 treatment also decreased the level of retinol dehydrogenase 10 (RDH10), thereby inhibiting the conversion of retinol to retinoic acid, causing the inability to initiate meiosis. Retinoic acid treatment could rescue the meiotic initiation and spermatogenesis while not affecting the intracellular copper ion levels. The study provided an insight into the bio-safety of NSC319726. Retinoic acid could be a potential therapy for spermatogenesis impairment in patients undergoing treatment with NSC319726.
      PubDate: 2024-05-01
       
  • Elongin B promotes breast cancer progression by ubiquitinating tumor
           suppressor p14/ARF

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      Abstract: Elongin B (ELOB), a pivotal element in the ELOB/c-Cullin2/5-SOCS-box E3 ubiquitin-protein ligase complex, plays a significant role in catalyzing the ubiquitination and subsequent degradation of a broad spectrum of target proteins. Notably, it is documented to facilitate these processes. However, the regulatory role of ELOB in breast cancer remains ambiguous. In this study, through bio-informatic analysis of The Cancer Genome Atlas and Fudan University Shanghai Cancer Center database, we demonstrated that ELOB was over-expressed in breast cancer tissues and was related to unfavorable prognosis. Additionally, pathway enrichment analysis illustrated that high expression of ELOB was associated with multiple cancer promoting pathways, like cell cycle, DNA replication, proteasome and PI3K − Akt signaling pathway, indicating ELOB as a potential anticancer target. Then, we confirmed that both in vivo and in vitro, the proliferation of breast cancer cells could be significantly suppressed by the down-regulation of ELOB. Mechanically, immunoprecipitation and in vivo ubiquitination assays prompted that, as the core element of Cullin2-RBX1-ELOB E3 ligase (CRL2) complex, ELOB regulated the ubiquitination and the subsequent degradation of oncoprotein p14/ARF. Moreover, the anticancer efficacy of erasing ELOB could be rescued by simultaneous knockdown of p14/ARF. Finally, through analyzing breast cancer tissue microarrays and western blot of patient samples, we demonstrated that the expression of ELOB in tumor tissues was elevated in compared to adjacent normal tissues. In conclusion, ELOB is identified to be a promising innovative target for the drug development of breast cancer by promoting the ubiquitination and degradation of oncoprotein p14/ARF. Graphical headlights ELOB is highly expressed in breast cancer. High ELOB levels were positively associated with poor prognosis. ELOB promotes p14/ARF degradation as part of the Cullin2-RBX1-ELOB E3 ligase complex. ELOB is a promising biomarker for breast cancer. Graphical
      PubDate: 2024-04-23
       
 
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  Subjects -> ENVIRONMENTAL STUDIES (Total: 913 journals)
    - ENVIRONMENTAL STUDIES (810 journals)
    - POLLUTION (31 journals)
    - TOXICOLOGY AND ENVIRONMENTAL SAFETY (54 journals)
    - WASTE MANAGEMENT (18 journals)

ENVIRONMENTAL STUDIES (810 journals)                  1 2 3 4 5 | Last

Showing 1 - 200 of 378 Journals sorted alphabetically
ACS Chemical Health & Safety     Hybrid Journal   (Followers: 4)
ACS Environmental Au     Open Access   (Followers: 12)
ACS ES&T Engineering     Hybrid Journal   (Followers: 5)
Acta Brasiliensis     Open Access  
Acta Ecologica Sinica     Open Access   (Followers: 10)
Acta Oecologica     Hybrid Journal   (Followers: 12)
Advanced Electronic Materials     Hybrid Journal   (Followers: 16)
Advanced Energy and Sustainability Research     Open Access   (Followers: 8)
Advanced Membranes     Open Access   (Followers: 9)
Advanced Sustainable Systems     Hybrid Journal   (Followers: 7)
Advances in Ecological Research     Full-text available via subscription   (Followers: 47)
Advances in Environmental Chemistry     Open Access   (Followers: 17)
Advances in Environmental Sciences - International Journal of the Bioflux Society     Open Access   (Followers: 17)
Advances in Environmental Technology     Open Access   (Followers: 3)
Advances in Life Science and Technology     Open Access   (Followers: 14)
Advances in Tropical Biodiversity and Environmental Sciences     Open Access   (Followers: 5)
Aeolian Research     Hybrid Journal   (Followers: 7)
Agricultura Tecnica     Open Access   (Followers: 2)
Agricultural & Environmental Letters     Open Access   (Followers: 4)
Agro-Science     Full-text available via subscription   (Followers: 2)
Agroecological journal     Open Access   (Followers: 1)
Agronomy for Sustainable Development     Open Access   (Followers: 19)
Agrosystems, Geosciences & Environment     Open Access   (Followers: 5)
Amazon's Research and Environmental Law     Open Access   (Followers: 5)
Ambiens. Revista Iberoamericana Universitaria en Ambiente, Sociedad y Sustentabilidad     Open Access  
Ambiente & sociedade     Open Access   (Followers: 3)
American Journal of Energy and Environment     Open Access   (Followers: 6)
American Journal of Environmental Engineering     Open Access   (Followers: 6)
American Journal of Environmental Protection     Open Access   (Followers: 5)
American Journal of Environmental Sciences     Open Access   (Followers: 10)
American Naturalist     Full-text available via subscription   (Followers: 82)
Animal - Open Space     Open Access   (Followers: 6)
Annals of Civil and Environmental Engineering     Open Access   (Followers: 2)
Annals of Environmental Science and Toxicology     Open Access   (Followers: 4)
Annals of GIS     Open Access   (Followers: 31)
Annual Review of Ecology, Evolution, and Systematics     Full-text available via subscription   (Followers: 85)
Annual Review of Environment and Resources     Full-text available via subscription   (Followers: 18)
Annual Review of Pharmacology and Toxicology     Full-text available via subscription   (Followers: 27)
Annual Review of Resource Economics     Full-text available via subscription   (Followers: 13)
Applied and Environmental Soil Science     Open Access   (Followers: 14)
Applied Ecology and Environmental Sciences     Open Access   (Followers: 30)
Applied Environmental Education & Communication     Hybrid Journal   (Followers: 18)
Applied Journal of Environmental Engineering Science     Open Access   (Followers: 2)
Aquatic Ecology     Hybrid Journal   (Followers: 45)
Aquatic Toxicology     Hybrid Journal   (Followers: 26)
Arcada : Revista de conservación del patrimonio cultural     Open Access   (Followers: 1)
Architecture, Civil Engineering, Environment     Open Access   (Followers: 6)
Archives des Maladies Professionnelles et de l'Environnement     Full-text available via subscription  
Archives of Environmental and Occupational Health     Hybrid Journal   (Followers: 10)
Archives of Environmental Contamination and Toxicology     Hybrid Journal   (Followers: 12)
Archives of Environmental Protection     Open Access   (Followers: 5)
Archives of Toxicology     Hybrid Journal   (Followers: 17)
Arctic Environmental Research     Open Access  
Asian Journal of Environment & Ecology     Open Access   (Followers: 3)
Asian Journal of Rural Development     Open Access   (Followers: 10)
Asian Review of Environmental and Earth Sciences     Open Access   (Followers: 2)
ATBU Journal of Environmental Technology     Open Access   (Followers: 1)
Atmospheric and Climate Sciences     Open Access   (Followers: 37)
Atmospheric Environment     Hybrid Journal   (Followers: 71)
Atmospheric Environment : X     Open Access   (Followers: 3)
Augm Domus : Revista electrónica del Comité de Medio Ambiente de AUGM     Open Access  
Austral Ecology     Hybrid Journal   (Followers: 17)
Australasian Journal of Environmental Management     Hybrid Journal   (Followers: 9)
Australasian Journal of Human Security     Full-text available via subscription   (Followers: 2)
Australian Journal of Environmental Education     Full-text available via subscription   (Followers: 11)
Basic & Clinical Pharmacology & Toxicology     Hybrid Journal   (Followers: 11)
Basic and Applied Ecology     Hybrid Journal   (Followers: 23)
Behavioral Ecology     Hybrid Journal   (Followers: 58)
Behavioral Ecology and Sociobiology     Hybrid Journal   (Followers: 36)
Biocenosis     Open Access  
Biochar     Hybrid Journal   (Followers: 1)
Biodegradation     Hybrid Journal   (Followers: 2)
Biodiversity     Hybrid Journal   (Followers: 30)
Biofouling: The Journal of Bioadhesion and Biofilm Research     Hybrid Journal   (Followers: 2)
Bioremediation Journal     Hybrid Journal   (Followers: 4)
BioRisk     Open Access   (Followers: 2)
Boletín Semillas Ambientales     Open Access  
Bothalia : African Biodiversity & Conservation     Open Access  
Built Environment     Full-text available via subscription   (Followers: 8)
Bulletin of Environmental Contamination and Toxicology     Hybrid Journal   (Followers: 10)
Bulletin of the American Meteorological Society     Open Access   (Followers: 64)
Bumi Lestari Journal of Environment     Open Access  
Canadian Journal of Earth Sciences     Hybrid Journal   (Followers: 22)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 55)
Canadian Journal of Soil Science     Full-text available via subscription   (Followers: 12)
Canadian Water Resources Journal     Hybrid Journal   (Followers: 18)
Capitalism Nature Socialism     Hybrid Journal   (Followers: 22)
Carbon Capture Science & Technology     Open Access   (Followers: 7)
Carbon Resources Conversion     Open Access   (Followers: 2)
Case Studies in Chemical and Environmental Engineering     Open Access  
Cell Biology and Toxicology     Hybrid Journal   (Followers: 8)
Chain Reaction     Full-text available via subscription  
Challenges in Sustainability     Open Access   (Followers: 11)
Chemical Research in Toxicology     Hybrid Journal   (Followers: 20)
Chemico-Biological Interactions     Hybrid Journal   (Followers: 1)
Chemosphere     Hybrid Journal   (Followers: 19)
Child and Adolescent Mental Health     Hybrid Journal   (Followers: 72)
Chinese Journal of Environmental Law     Hybrid Journal   (Followers: 2)
Ciencia, Ambiente y Clima     Open Access   (Followers: 1)
City and Environment Interactions     Open Access   (Followers: 3)
Civil and Environmental Engineering     Open Access   (Followers: 7)
Civil and Environmental Engineering Reports     Open Access   (Followers: 4)
Civil and Environmental Research     Open Access   (Followers: 14)
CLEAN - Soil, Air, Water     Hybrid Journal   (Followers: 19)
Clean Technologies     Open Access   (Followers: 1)
Clean Technologies and Environmental Policy     Hybrid Journal   (Followers: 5)
Cleaner and Circular Bioeconomy (CLCB)     Open Access   (Followers: 6)
Cleaner Energy Systems     Open Access   (Followers: 3)
Cleaner Environmental Systems     Open Access   (Followers: 1)
Cleaner Production Letters     Hybrid Journal   (Followers: 1)
Cleaner Waste Systems     Open Access   (Followers: 2)
Cleanroom Technology     Full-text available via subscription   (Followers: 1)
Climate and Energy     Full-text available via subscription   (Followers: 12)
Climate Change Ecology     Open Access   (Followers: 30)
Climate Change Economics     Hybrid Journal   (Followers: 52)
Climate Policy     Hybrid Journal   (Followers: 60)
Climate Resilience and Sustainability     Open Access   (Followers: 35)
Coastal Engineering Journal     Hybrid Journal   (Followers: 9)
Cogent Environmental Science     Open Access  
Columbia Journal of Environmental Law     Open Access   (Followers: 15)
Computational Ecology and Software     Open Access   (Followers: 9)
Computational Water, Energy, and Environmental Engineering     Open Access   (Followers: 6)
Conservation and Society     Open Access   (Followers: 14)
Conservation Letters     Open Access   (Followers: 52)
Conservation Science     Open Access   (Followers: 28)
Consilience : The Journal of Sustainable Development     Open Access   (Followers: 2)
Contemporary Problems of Ecology     Hybrid Journal   (Followers: 4)
Critical Reviews in Environmental Science and Technology     Hybrid Journal   (Followers: 10)
Critical Reviews in Toxicology     Hybrid Journal   (Followers: 22)
Cuadernos de Investigación Geográfica / Geographical Research Letters     Open Access  
Culture, Agriculture, Food and Environment     Hybrid Journal   (Followers: 24)
Culture, Agriculture, Food and Environment     Hybrid Journal   (Followers: 8)
Current Environmental Health Reports     Hybrid Journal   (Followers: 2)
Current Forestry Reports     Hybrid Journal   (Followers: 1)
Current Landscape Ecology Reports     Hybrid Journal   (Followers: 3)
Current Opinion in Environmental Science & Health     Hybrid Journal  
Current Opinion in Environmental Sustainability     Hybrid Journal   (Followers: 14)
Current Research in Ecological and Social Psychology     Open Access   (Followers: 7)
Current Research in Environmental Sustainability     Open Access   (Followers: 5)
Current Research in Green and Sustainable Chemistry     Open Access   (Followers: 1)
Current Research in Microbiology     Open Access   (Followers: 20)
Current Sustainable/Renewable Energy Reports     Hybrid Journal   (Followers: 7)
Die Bodenkultur : Journal of Land Management, Food and Environment     Open Access  
Disaster Prevention and Management     Hybrid Journal   (Followers: 27)
Discover Sustainability     Open Access   (Followers: 5)
disP - The Planning Review     Hybrid Journal   (Followers: 1)
Drug and Chemical Toxicology     Hybrid Journal   (Followers: 12)
Duke Environmental Law & Policy Forum     Open Access   (Followers: 9)
E3S Web of Conferences     Open Access  
Earth and Environmental Science Transactions of the Royal Society of Edinburgh     Hybrid Journal   (Followers: 7)
Earth Interactions     Open Access   (Followers: 10)
Earth Science Informatics     Hybrid Journal   (Followers: 6)
Earth System Governance     Open Access   (Followers: 4)
Earth System Science Data (ESSD)     Open Access   (Followers: 7)
Earth Systems and Environment     Hybrid Journal   (Followers: 4)
Earthquake Science     Hybrid Journal   (Followers: 11)
EchoGéo     Open Access  
Eco-Environment & Health     Open Access   (Followers: 6)
Eco-Thinking     Open Access   (Followers: 4)
Ecocycles     Open Access   (Followers: 4)
Ecohydrology     Hybrid Journal   (Followers: 13)
Ecohydrology & Hydrobiology     Full-text available via subscription   (Followers: 5)
Ecologia Aplicada     Open Access  
Ecología en Bolivia     Open Access  
Ecological Applications     Full-text available via subscription   (Followers: 205)
Ecological Chemistry and Engineering S     Open Access   (Followers: 4)
Ecological Complexity     Hybrid Journal   (Followers: 8)
Ecological Engineering     Hybrid Journal   (Followers: 7)
Ecological Indicators     Hybrid Journal   (Followers: 22)
Ecological Informatics     Hybrid Journal   (Followers: 4)
Ecological Management & Restoration     Hybrid Journal   (Followers: 17)
Ecological Modelling     Hybrid Journal   (Followers: 74)
Ecological Monographs     Full-text available via subscription   (Followers: 38)
Ecological Processes     Open Access   (Followers: 2)
Ecological Questions     Open Access   (Followers: 5)
Ecological Research     Hybrid Journal   (Followers: 10)
Ecological Restoration     Full-text available via subscription   (Followers: 25)
Ecologist, The     Full-text available via subscription   (Followers: 23)
Ecology     Full-text available via subscription   (Followers: 425)
Ecology and Evolution     Open Access   (Followers: 106)
Ecology Letters     Hybrid Journal   (Followers: 285)
EcoMat : Functional Materials for Green Energy and Environment     Open Access  
Economics and Policy of Energy and the Environment     Full-text available via subscription   (Followers: 16)
Economics of Energy & Environmental Policy     Hybrid Journal   (Followers: 3)
Économie rurale     Open Access   (Followers: 3)
Ecoprint : An International Journal of Ecology     Open Access   (Followers: 4)
Ecopsychology     Hybrid Journal   (Followers: 7)
Ecosphere     Open Access   (Followers: 12)
Ecosystem Services     Hybrid Journal   (Followers: 8)
Ecosystems     Hybrid Journal   (Followers: 33)
Ecosystems and People     Open Access   (Followers: 4)
Ecotoxicology     Hybrid Journal   (Followers: 8)
Ecotoxicology and Environmental Safety     Hybrid Journal   (Followers: 10)
Ecotrophic : Journal of Environmental Science     Open Access  
Ecozon@ : European Journal of Literature, Culture and Environment     Open Access   (Followers: 3)
Éducation relative à l'environnement     Open Access  
Electronic Green Journal     Open Access   (Followers: 4)
Empowering Sustainability International Journal     Open Access   (Followers: 4)
Energy & Environment     Hybrid Journal   (Followers: 25)
Energy & Environmental Science     Hybrid Journal   (Followers: 37)

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