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Authors:Zahra Khodabandeh; Sanaz Alaee, Mohammad Samare-Najaf, Elham Hosseini, Mahintaj Dara, Saeed Shokri, Reza Shirazi1Stem Cells Technology Research Center, 48435Shiraz University of Medical Sciences, Shiraz, Iran2Department of Reproductive Biology, School of Advanced Medical Sciences Health, 7800UNSW Sydney, Sydney, NSW, Australia Abstract: Toxicology and Industrial Health, Ahead of Print. Acrylamide (Acr) poses reproductive toxicity risks to humans due to its ability to penetrate cell membranes and disrupt cellular balance. Taurine (Tau), a sulfur-containing amino acid with cell membrane stabilization and antioxidant properties, may ... Citation: Toxicology and Industrial Health PubDate: 2025-04-18T10:17:54Z DOI: 10.1177/07482337251335541
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Authors:Fatih Mehmet Ateş; Ömer Doğan1Occupational Health Safety Program, Technical Sciences Vocational School, 187433Bayburt University, Bayburt, Turkey2Computer Programming Program, Bandırma Vocational School, 450200Bandırma Onyedi Eylül University, Balıkesir, Turkey Abstract: Toxicology and Industrial Health, Ahead of Print. Risk assessment is necessary for the safety of employees in the workplace. Risk assessment methods contain some deficiencies arising from the persons performing the analysis. In order to partially overcome this situation, a risk assessment method has been ... Citation: Toxicology and Industrial Health PubDate: 2025-04-16T11:14:35Z DOI: 10.1177/07482337251333164
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Abstract: Toxicology and Industrial Health, Ahead of Print.
Citation: Toxicology and Industrial Health PubDate: 2025-04-02T07:10:23Z DOI: 10.1177/07482337251332187
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Abstract: Toxicology and Industrial Health, Ahead of Print.
Citation: Toxicology and Industrial Health PubDate: 2025-03-29T10:42:44Z DOI: 10.1177/07482337251332193
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Authors: Hemlata; Monika Rani, Anil Kumar, Saurabh Sudha Dhiman, Kanu Priya, Anuradha Bhardwaj, Gulab Singh, Anita Saini, Shiv Kumar Giri1Department of Biotechnology, School of Basic Applied Sciences, Maharaja Agrasen University, Baddi (HP), India Abstract: Toxicology and Industrial Health, Ahead of Print. Organophosphate pesticides, widely used in agriculture, are effective in pest control but pose environmental and health risks through soil, water, and air contamination. Exposure to these chemicals is linked to adverse human health effects, underscoring ... Citation: Toxicology and Industrial Health PubDate: 2025-03-19T01:32:23Z DOI: 10.1177/07482337251325578
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Authors:Pattama Senthong; Sivasit Wittayasilp, Kantima Ladondu, Kodchapan Noochana1Faculty of Science Manufacturing Engineering, Faculty of Engineering, Prince of Songkla University, Hat Yai, Songkhla, Thailand Abstract: Toxicology and Industrial Health, Ahead of Print. The aim of this study was to quantify VOC concentrations in different ventilation conditions, Wet Bulb Globe Temperature (WBGT), illumination and noise levels in two automobile repair shops. A cross-sectional study was conducted at two shops in Surat ... Citation: Toxicology and Industrial Health PubDate: 2025-03-17T11:33:38Z DOI: 10.1177/07482337251324989
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Authors:Ranil Kavindra Asela Kularatne1School of Environment; Ecology Biomedicine, La Trobe University, Bundoora, VIC, Australia2Faculty of Graduate Studies, University of Colombo, Colombo, Sri Lanka3Kularatne Associates, No. 16, Samudra Sanna Road, Mount Lavinia, Sri Lanka Abstract: Toxicology and Industrial Health, Ahead of Print. This article presents a preliminary commentary on the Safety Data Sheets (SDS) and chemical labels of reproductive toxicant chemicals frequently used in biotechnology laboratories. This included six chemicals (chloroform, acrylamide, cobalt chloride ... Citation: Toxicology and Industrial Health PubDate: 2025-03-13T07:21:19Z DOI: 10.1177/07482337251320750
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Authors:Preeti Bagri, Satish Kumar Jain; Satish Kumar JainDepartment of Veterinary Pharmacology Animal Sciences, Hisar, India Abstract: Toxicology and Industrial Health, Ahead of Print. Pesticides are applied to plants all over the world to boost food production and lower the spread of diseases carried by insects. Exposure to the pesticides may cause genotoxic effects on target and non-target organisms, including humans. In agriculture, acetamiprid (ACE), a neonicotinoid insecticide, is frequently applied either alone or in conjunction with other pesticides. A combined approach employing the micronucleus test (MNT) and chromosomal aberrations (CAs) assay was used to evaluate the genotoxic effects of acetamiprid in the bone marrow of male Swiss albino mice. Acetamiprid was administered i.p. daily at 4.6 and 2.3 mg/kg/day along with 3% gum acacia as a negative control for 30 days. ACE treatment resulted in a small dose dependent increase in the frequencies of micronuclei per cell (0.28 ± 0.04, 0.38 ± 0.03, and 0.45 ± 0.02 for the control, 2.3 and 4.6 mg/kg b.wt. groups, respectively) and chromosomal aberrations (3.67 ± 0.61, 5.00 ± 0.45, and 7.00 ± 1.43 for the control, 2.3 and 4.6 mg/kg b.wt. groups, respectively) in bone marrow cells, but no significant differences were observed between these data sets. In conclusion, daily i.p. exposure of ACE @ 2.3 and 4.6 mg/kg b.wt. for 30 days did not produce significant genotoxic effects in the somatic cells of Swiss albino male mice. Citation: Toxicology and Industrial Health PubDate: 2025-03-03T03:34:53Z DOI: 10.1177/07482337251323055
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Abstract: Toxicology and Industrial Health, Ahead of Print. Methyltrimethoxysilane (MTMS) has been used as a coupling agent in thermoplastics and thermosetting resins, a cross-linker in silicone sealants, a water repellent component, and in silicone hard-coats for plastics. Acute studies in experimental animals showed a low order of toxicity for MTMS via oral, dermal, and inhalation routes. MTMS was slightly irritating to both eyes and skin in rabbits. A weight of evidence assessment supports that MTMS is not a dermal sensitizer. Available in vitro and in vivo assays indicated MTMS has a low potential for genotoxicity. MTMS did not produce any changes in either reproductive or developmental parameters. Short-term, repeated inhalation in rats produced treatment-related observations in the urinary bladder and kidney. In a 90-day inhalation study in rats, MTMS was associated with production of urinary bladder epithelial hyperplasia, calculi formation, and moderate kidney dilation with hyperplasia of the pelvic epithelium and granulomatous inflammation. However, an expert panel review concluded that changes in the bladder and kidney were adaptive responses to physical or chemical irritation. The NOAEL of 100 ppm (557 mg/m3) from the 90-day inhalation study was considered the point of departure for the health-based WEEL derivation. After adjusting to account for duration of exposure and interindividual variability, the resulting 8-h TWA WEEL value of 10 ppm (55 mg/m3) is fully expected to provide a significant margin of safety against potential adverse health effects in workers. Citation: Toxicology and Industrial Health PubDate: 2025-01-31T05:02:53Z DOI: 10.1177/07482337241301523
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