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  Subjects -> CHEMISTRY (Total: 841 journals)
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    - CHEMISTRY (593 journals)
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CHEMISTRY (593 journals)                  1 2 3 | Last

Showing 1 - 200 of 735 Journals sorted alphabetically
2D Materials     Hybrid Journal   (Followers: 8)
Accreditation and Quality Assurance: Journal for Quality, Comparability and Reliability in Chemical Measurement     Hybrid Journal   (Followers: 26)
ACS Catalysis     Full-text available via subscription   (Followers: 34)
ACS Chemical Neuroscience     Full-text available via subscription   (Followers: 18)
ACS Combinatorial Science     Full-text available via subscription   (Followers: 23)
ACS Macro Letters     Full-text available via subscription   (Followers: 23)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
ACS Nano     Full-text available via subscription   (Followers: 234)
ACS Photonics     Full-text available via subscription   (Followers: 11)
ACS Synthetic Biology     Full-text available via subscription   (Followers: 21)
Acta Chemica Iasi     Open Access   (Followers: 2)
Acta Chimica Sinica     Full-text available via subscription   (Followers: 1)
Acta Chimica Slovaca     Open Access   (Followers: 1)
Acta Chromatographica     Full-text available via subscription   (Followers: 9)
Acta Facultatis Medicae Naissensis     Open Access  
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5)
Acta Scientifica Naturalis     Open Access   (Followers: 2)
adhäsion KLEBEN & DICHTEN     Hybrid Journal   (Followers: 5)
Adhesion Adhesives & Sealants     Hybrid Journal   (Followers: 7)
Adsorption Science & Technology     Full-text available via subscription   (Followers: 5)
Advanced Functional Materials     Hybrid Journal   (Followers: 50)
Advanced Science Focus     Free   (Followers: 3)
Advances in Chemical Engineering and Science     Open Access   (Followers: 55)
Advances in Chemical Science     Open Access   (Followers: 13)
Advances in Chemistry     Open Access   (Followers: 14)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Enzyme Research     Open Access   (Followers: 9)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 15)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8)
Advances in Materials Physics and Chemistry     Open Access   (Followers: 19)
Advances in Nanoparticles     Open Access   (Followers: 15)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15)
Advances in Polymer Science     Hybrid Journal   (Followers: 41)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 19)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Science and Technology     Full-text available via subscription   (Followers: 12)
African Journal of Bacteriology Research     Open Access  
African Journal of Chemical Education     Open Access   (Followers: 2)
African Journal of Pure and Applied Chemistry     Open Access   (Followers: 7)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Journal of Biochemistry and Biotechnology     Open Access   (Followers: 69)
American Journal of Biochemistry and Molecular Biology     Open Access   (Followers: 14)
American Journal of Chemistry     Open Access   (Followers: 26)
American Journal of Plant Physiology     Open Access   (Followers: 14)
American Mineralogist     Hybrid Journal   (Followers: 14)
Analyst     Full-text available via subscription   (Followers: 40)
Angewandte Chemie     Hybrid Journal   (Followers: 204)
Angewandte Chemie International Edition     Hybrid Journal   (Followers: 214)
Annales UMCS, Chemia     Open Access   (Followers: 1)
Annals of Clinical Chemistry and Laboratory Medicine     Open Access   (Followers: 2)
Annual Reports in Computational Chemistry     Full-text available via subscription   (Followers: 3)
Annual Reports Section A (Inorganic Chemistry)     Full-text available via subscription   (Followers: 4)
Annual Reports Section B (Organic Chemistry)     Full-text available via subscription   (Followers: 8)
Annual Review of Chemical and Biomolecular Engineering     Full-text available via subscription   (Followers: 12)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 15)
Anti-Infective Agents     Hybrid Journal   (Followers: 3)
Antiviral Chemistry and Chemotherapy     Hybrid Journal  
Applied Organometallic Chemistry     Hybrid Journal   (Followers: 7)
Applied Spectroscopy     Full-text available via subscription   (Followers: 23)
Applied Surface Science     Hybrid Journal   (Followers: 28)
Arabian Journal of Chemistry     Open Access   (Followers: 6)
ARKIVOC     Open Access   (Followers: 2)
Asian Journal of Biochemistry     Open Access   (Followers: 1)
Atomization and Sprays     Full-text available via subscription   (Followers: 4)
Australian Journal of Chemistry     Hybrid Journal   (Followers: 7)
Autophagy     Hybrid Journal   (Followers: 2)
Avances en Quimica     Open Access   (Followers: 1)
Biochemical Pharmacology     Hybrid Journal   (Followers: 10)
Biochemistry     Full-text available via subscription   (Followers: 293)
Biochemistry Insights     Open Access   (Followers: 6)
Biochemistry Research International     Open Access   (Followers: 6)
BioChip Journal     Hybrid Journal  
Bioinorganic Chemistry and Applications     Open Access   (Followers: 9)
Bioinspired Materials     Open Access   (Followers: 5)
Biointerface Research in Applied Chemistry     Open Access   (Followers: 2)
Biointerphases     Open Access   (Followers: 1)
Biology, Medicine, & Natural Product Chemistry     Open Access   (Followers: 1)
Biomacromolecules     Full-text available via subscription   (Followers: 19)
Biomass Conversion and Biorefinery     Partially Free   (Followers: 10)
Biomedical Chromatography     Hybrid Journal   (Followers: 6)
Biomolecular NMR Assignments     Hybrid Journal   (Followers: 3)
BioNanoScience     Partially Free   (Followers: 4)
Bioorganic & Medicinal Chemistry     Hybrid Journal   (Followers: 124)
Bioorganic & Medicinal Chemistry Letters     Hybrid Journal   (Followers: 98)
Bioorganic Chemistry     Hybrid Journal   (Followers: 10)
Biopolymers     Hybrid Journal   (Followers: 18)
Biosensors     Open Access   (Followers: 2)
Biotechnic and Histochemistry     Hybrid Journal   (Followers: 1)
Bitácora Digital     Open Access  
Boletin de la Sociedad Chilena de Quimica     Open Access  
Bulletin of the Chemical Society of Ethiopia     Open Access   (Followers: 2)
Bulletin of the Chemical Society of Japan     Full-text available via subscription   (Followers: 24)
Bulletin of the Korean Chemical Society     Hybrid Journal   (Followers: 1)
C - Journal of Carbon Research     Open Access   (Followers: 3)
Cakra Kimia (Indonesian E-Journal of Applied Chemistry)     Open Access  
Canadian Association of Radiologists Journal     Full-text available via subscription   (Followers: 3)
Canadian Journal of Chemistry     Hybrid Journal   (Followers: 10)
Canadian Mineralogist     Full-text available via subscription   (Followers: 3)
Carbohydrate Research     Hybrid Journal   (Followers: 26)
Carbon     Hybrid Journal   (Followers: 66)
Catalysis for Sustainable Energy     Open Access   (Followers: 7)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 6)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysts     Open Access   (Followers: 8)
Cellulose     Hybrid Journal   (Followers: 7)
Cereal Chemistry     Full-text available via subscription   (Followers: 4)
ChemBioEng Reviews     Full-text available via subscription   (Followers: 1)
ChemCatChem     Hybrid Journal   (Followers: 8)
Chemical and Engineering News     Free   (Followers: 13)
Chemical Bulletin of Kazakh National University     Open Access  
Chemical Communications     Full-text available via subscription   (Followers: 71)
Chemical Engineering Research and Design     Hybrid Journal   (Followers: 23)
Chemical Research in Chinese Universities     Hybrid Journal   (Followers: 3)
Chemical Research in Toxicology     Full-text available via subscription   (Followers: 19)
Chemical Reviews     Full-text available via subscription   (Followers: 176)
Chemical Science     Open Access   (Followers: 22)
Chemical Technology     Open Access   (Followers: 16)
Chemical Vapor Deposition     Hybrid Journal   (Followers: 5)
Chemical Week     Full-text available via subscription   (Followers: 8)
Chemie in Unserer Zeit     Hybrid Journal   (Followers: 57)
Chemie-Ingenieur-Technik (Cit)     Hybrid Journal   (Followers: 26)
ChemInform     Hybrid Journal   (Followers: 8)
Chemistry & Biodiversity     Hybrid Journal   (Followers: 6)
Chemistry & Biology     Full-text available via subscription   (Followers: 30)
Chemistry & Industry     Hybrid Journal   (Followers: 5)
Chemistry - A European Journal     Hybrid Journal   (Followers: 143)
Chemistry - An Asian Journal     Hybrid Journal   (Followers: 15)
Chemistry and Materials Research     Open Access   (Followers: 18)
Chemistry Central Journal     Open Access   (Followers: 4)
Chemistry Education Research and Practice     Free   (Followers: 5)
Chemistry in Education     Open Access   (Followers: 9)
Chemistry International     Hybrid Journal   (Followers: 2)
Chemistry Letters     Full-text available via subscription   (Followers: 45)
Chemistry of Materials     Full-text available via subscription   (Followers: 260)
Chemistry of Natural Compounds     Hybrid Journal   (Followers: 9)
Chemistry World     Full-text available via subscription   (Followers: 22)
Chemistry-Didactics-Ecology-Metrology     Open Access   (Followers: 1)
ChemistryOpen     Open Access   (Followers: 2)
Chemkon - Chemie Konkret, Forum Fuer Unterricht Und Didaktik     Hybrid Journal  
Chemoecology     Hybrid Journal   (Followers: 3)
Chemometrics and Intelligent Laboratory Systems     Hybrid Journal   (Followers: 15)
Chemosensors     Open Access  
ChemPhysChem     Hybrid Journal   (Followers: 9)
ChemPlusChem     Hybrid Journal   (Followers: 2)
ChemTexts     Hybrid Journal  
CHIMIA International Journal for Chemistry     Full-text available via subscription   (Followers: 2)
Chinese Journal of Chemistry     Hybrid Journal   (Followers: 6)
Chinese Journal of Polymer Science     Hybrid Journal   (Followers: 10)
Chromatographia     Hybrid Journal   (Followers: 24)
Clay Minerals     Full-text available via subscription   (Followers: 10)
Cogent Chemistry     Open Access  
Colloid and Interface Science Communications     Open Access  
Colloid and Polymer Science     Hybrid Journal   (Followers: 10)
Colloids and Surfaces B: Biointerfaces     Hybrid Journal   (Followers: 7)
Combinatorial Chemistry & High Throughput Screening     Hybrid Journal   (Followers: 4)
Combustion Science and Technology     Hybrid Journal   (Followers: 18)
Comments on Inorganic Chemistry: A Journal of Critical Discussion of the Current Literature     Hybrid Journal   (Followers: 2)
Composite Interfaces     Hybrid Journal   (Followers: 6)
Comprehensive Chemical Kinetics     Full-text available via subscription   (Followers: 2)
Comptes Rendus Chimie     Full-text available via subscription  
Comptes Rendus Physique     Full-text available via subscription   (Followers: 1)
Computational and Theoretical Chemistry     Hybrid Journal   (Followers: 9)
Computational Biology and Chemistry     Hybrid Journal   (Followers: 12)
Computational Chemistry     Open Access   (Followers: 2)
Computers & Chemical Engineering     Hybrid Journal   (Followers: 9)
Coordination Chemistry Reviews     Full-text available via subscription   (Followers: 2)
Copernican Letters     Open Access   (Followers: 1)
Critical Reviews in Biochemistry and Molecular Biology     Hybrid Journal   (Followers: 5)
Crystal Structure Theory and Applications     Open Access   (Followers: 3)
CrystEngComm     Full-text available via subscription   (Followers: 12)
Current Catalysis     Hybrid Journal   (Followers: 2)
Current Metabolomics     Hybrid Journal   (Followers: 5)
Current Opinion in Colloid & Interface Science     Hybrid Journal   (Followers: 9)
Current Research in Chemistry     Open Access   (Followers: 8)
Current Science     Open Access   (Followers: 58)
Dalton Transactions     Full-text available via subscription   (Followers: 22)
Detection     Open Access   (Followers: 2)
Developments in Geochemistry     Full-text available via subscription   (Followers: 2)
Diamond and Related Materials     Hybrid Journal   (Followers: 12)
Dislocations in Solids     Full-text available via subscription  
Doklady Chemistry     Hybrid Journal  
Drying Technology: An International Journal     Hybrid Journal   (Followers: 4)
Eclética Química     Open Access   (Followers: 1)
Ecological Chemistry and Engineering S     Open Access   (Followers: 4)
Ecotoxicology and Environmental Contamination     Open Access  
Educación Química     Open Access   (Followers: 1)
Education for Chemical Engineers     Hybrid Journal   (Followers: 5)
EJNMMI Radiopharmacy and Chemistry     Open Access  
Elements     Full-text available via subscription   (Followers: 2)
Environmental Chemistry     Hybrid Journal   (Followers: 9)
Environmental Chemistry Letters     Hybrid Journal   (Followers: 4)
Environmental Science & Technology Letters     Full-text available via subscription   (Followers: 5)
Environmental Science : Nano     Partially Free   (Followers: 1)
Environmental Toxicology & Chemistry     Hybrid Journal   (Followers: 18)

        1 2 3 | Last

Journal Cover Applied Organometallic Chemistry
  [SJR: 0.632]   [H-I: 58]   [7 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 0268-2605 - ISSN (Online) 1099-0739
   Published by John Wiley and Sons Homepage  [1577 journals]
  • Synthesis and structural and DNA binding studies of mono- and dinuclear
           copper(II) complexes constructed with ─O and ─N donor ligands:
           Potential anti-skin cancer drugs
    • Authors: Champaka Gurudevaru; Mohan Gopalakrishnan, Kabali Senthilkumar, Hridya Hemachandran, Ramamoorthy Siva, Thothadri Srinivasan, Devadasan Velmurugan, Swaminathan Shanmugan, Nallasamy Palanisami
      Abstract: Mononuclear and dinuclear copper(II) complexes with thiophenecarboxylic acid, [Cu(3-TCA)2(2,2′-bpy)] (1), [Cu(3-Me-2-TCA)2(H2O)(2,2′-bpy)] (2), [Cu(5-Me-2-TCA)2(H2O)(2,2′-bpy)] (3) and [Cu2(2,5-TDCA)(DMF)2(H2O)2(2,2′-bpy)2](ClO4)2 (4) (where 3-TCA = 3-thiophenecarboxylic acid; 3-Me-2-TCA = 3-methyl-2-thiophenecarboxylic acid; 5-Me-2-TCA = 5-methyl-2-thiophenecarboxylic acid; 2,5-TDCA = thiophene-2,5-dicarboxylic acid; 2,2′-bpy = 2,2′-bipyridyl; DMF = N,N-dimethylformamide), were synthesized. Compounds 1–4 were extensively characterized using both analytical and spectroscopic methods. Additionally, the solid-state structures of 1 and 4 were unambiguously established from single-crystal X-ray diffraction studies. The hexacoordinated Cu(II) centre in 1 (CuO4N2) is a distorted octahedral geometry whereas the pentacoodinated 4 (CuO3N2) has distorted square pyramidal geometry. Compounds 1 and 4 exhibit intermolecular hydrogen bonding which leads to the formation of two- and three-dimensional supramolecular architectures, respectively. Spectrophotometric and computational investigations suggest that these compounds bind with DNA in minor groove binding such that Kb = 4.9 × 105 M−1 and Ksv = 3.4 × 105 M−1, and binding score of −5.26 kcal mol−1. The binding affinity of these complexes to calf thymus DNA is in the order 2 > 3 > 4 > 1. Methyl-substituted thiophene ring increases the DNA binding affinity whereas unsubstituted thiophene ring DNA binding rate is reduced. The methyl group on the thiophene ring would sterically hinder π–π stacking of the ring with DNA base pairs, and subsequently they are involved in hydrophobic interaction with the DNA surface rather than partial intercalative interaction. Compounds 1–4 show pronounced activity against B16 mouse melanoma skin cancer cell lines as measured by MTT assay yielding IC50 values in the micromolar concentration range. The compounds could prove to be efficient anti-cancer agents, since at a concentration as low as 2.1 μg ml−1 they exerted a significant cytotoxic effect in cancer cells whereas cell viability was not affected in normal cells.Copper(II) complexes (1–4) of thiophenecarboxylic acid with 2,2′-bipydine were synthesized and characterized. Compounds 1 and 4 exhibit hydrogen bonding as well as π–π stacking interactions which lead to polymeric structures. Compounds 1–4 have strong binding activity towards calf thymus DNA. Compound 2 has better binding activity than its thiophene analogues.
      PubDate: 2017-09-15T06:30:20.026155-05:
      DOI: 10.1002/aoc.3998
       
  • Sulfonated N-heterocyclic carbine-silver (I) complexes: Synthesis,
           characterisation and biological evaluation
    • Authors: Şeyma Yaşar; Tuğba Kul Köprülü, Şaban Tekin, Sedat Yaşar
      Abstract: The synthesis, characterisation and biological activity of water-soluble Ag(I)-NHC complexes, general formula Na[(NHC)AgCl] where NHC is a sulfonated and sterically hindered N-heterocyclic carbene, is reported. The Ag-NHC complexes (2a–e) were synthesised by reacting the corresponding sulfonated NHC ligands with Ag2O in the presence of NaCl or NaBr in methanol/water (1:1) solution. Synthesised silver (I)-N-heterocyclic carbene complexes have been characterised by NMR, micro-analysis and HRMS spectroscopic methods. The IC50 values of these complexes were determined by a proliferation BrdU enzyme-linked immunosorbent assay (ELISA) against HeLa (human cervix carcinoma), HT29 (human adenocarcinoma) and L929 (mouse fibroblast) cell lines. These complexes have been highlighted as promising and original platforms for building new types of metalodrug. All new water-soluble Ag(I) complexes demonstrated remarkable cytotoxic activity against HeLa, HT29 and L929 cell lines.Synthesised silver (I)-N- heterocyclic carbene complexes have been characterised by NMR, micro- analysis and HRMS spectroscopic methods. The IC50 values of these complexes were determined by a proliferation BrdU enzyme- linked immunosorbent assay (ELISA) against HeLa (human cervix carcinoma), HT29 (human adenocarcinoma) and L929 (mouse fibroblast) cell lines. These complexes have been highlighted as promising and original platforms for building new types of metalodrug.
      PubDate: 2017-09-15T06:27:56.82438-05:0
      DOI: 10.1002/aoc.4016
       
  • Boehmite nano-particles functionalized with silylpropylamine-supported
           Keggin-type heteropolyacids: Catalysts for epoxidation of alkenes
    • Authors: Mahdi Mirzaee; Bahram Bahramian, Azam Ashrafian, Adonis Amoli
      Abstract: Boehmite nano-particles with a high degree of surface hydroxyl groups were covalently functionalized by 3-(trimethoxysilyl)-propylamine to support H3[PMo12O40], H3[PW12O40], H4[SiMo12O40] and H4[SiW12O40] Keggin-type heteropolyacids. After characterization of these catalysts by FT-IR, powder X-ray diffraction, TG/differential thermal analysis, CHN, inductively coupled plasma and transmission electron microscopy techniques, they were applied to the epoxidation of cis-cycloocten. The progress of the reactions was investigated by gas–liquid chromatography, and the catalytic procedures were optimized for the parameters involved, such as the solvent and oxidant. The results showed that 25 mg of supported H3[PMo12O40] catalyst in 1 ml C2H4Cl2 with 0.5 mmol cyclooctene and 1 mmol tert-butylhydroperoxide at reflux temperature gave 98% yield over 15 min. Recycling experiments revealed that these nanocatalysts could be repeatedly applied up to five times for a nearly complete epoxidation of cis-cycloocten. The optimized experimental conditions were also used successfully for the epoxidation of some other alkenes, such as cyclohexene, styrene and α-methyl styrene.Boehmite nano-particles were covalently functionalized by 3-trimethoxysilyl(propylamine) to support Keggin type heteropolyacids for the catalytic epoxidation of alkenes. The results showed that the supported H3PMo12O40 catalyst in C2H4Cl2 with tert-butylhydroperoxide as oxidant at reflux condition gave complete conversion in epoxidation of cis-cyclooctene over the short time of only 15 minutes. It was also successfully recycled up to five times and could be used for the epoxidation of some other alkenes, such as cyclohexene, styrene and α-methyl styrene.
      PubDate: 2017-09-15T06:26:42.221558-05:
      DOI: 10.1002/aoc.4011
       
  • Silane-bridged diphosphine ligand for palladium-catalyzed ethylene
           oligomerization
    • Authors: YongWang Huang; Wei Wei, XueJiao Meng, Le Zhang, YanHui Chen, Tao Jiang
      Abstract: In this study, bis(diphenylphosphinemethyl)dimethyl silane (L1) and its palladium(II) halide complex, L1/PdCl2 (C1), were synthesized and characterized. Single-crystal X-ray analysis of the complex revealed bidentate coordination at the Pd center. In combination with methylaluminoxane (MAO) as co-catalyst, C1 exhibited excellent catalytic activity and selectivity for ethylene dimerization toward butene. The maximum catalytic activity obtained from the C1/MAO system for ethylene dimerization to yield butenes was 7.33 × 105 g/(molPd·h). The selectivity toward butene remained stable and high (> 96%) over the various conditions.Bis(diphenylphosphinemethyl)dimethyl silane (L1) and its palladium (II) halide complex, L1/PdCl2 (C1), were synthesized and characterized. In combination with methylaluminoxane (MAO) as co-catalyst, C1 complex showed high catalytic activity and selectivity for ethylene dimerization toward butene using toluene as solvent.
      PubDate: 2017-09-15T06:16:26.502273-05:
      DOI: 10.1002/aoc.4014
       
  • Adamantyl ferrocene derivatives: Antioxidant abilities and effects on
           model lipid membranes
    • Authors: Adela Štimac; Jasmina Lapić, Valentino Blasina, Marija Lukinac, Senka Djaković, Ivo Crnolatac, Leo Frkanec, Ruža Frkanec
      Abstract: A series of homoannularly and heteroannularly substituted adamantyl ferrocene derivatives has been synthesized and their effects on membrane fluidity were investigated using liposomes as the membrane models. The liposome formulations of adamantyl ferrocene derivatives were characterized by using dynamic light scattering, differential scanning calorimetry and fluorescence anisotropy measurements. It was demonstrated that adamantyl ferrocene derivatives incorporated into the liposome significantly affect the structure of the lipid bilayer. The results of the study have revealed that adamantyl ferrocene derivatives, compounds 9–12, partition into the hydrophobic/hydrophilic interface of the membrane, causing a significant decrease in membrane fluidity. The antioxidant potential of synthesized compounds was assessed with DPPH method and it was shown that the examined compounds possess certain antioxidant activity.A series of adamantyl ferrocene derivatives has been synthesized and their effects on membrane fluidity were investigated using liposomes as the membrane models. The liposome formulations of adamantyl ferrocene derivatives were characterized and it was demonstrated that the lipid bilayes of liposome were significantly affected. The results have revealed that examined compounds, partition into the hydrophobic/hydrophilic interface of the membrane, causing a significant decrease in membrane fluidity. It was shown that the examined compounds possess certain antioxidant activity.
      PubDate: 2017-09-15T06:15:38.210848-05:
      DOI: 10.1002/aoc.4042
       
  • Covalent bonding of magnetic Fe3O4 nanoparticles to
           aminopropyl-functionalized magnesium phyllosilicate clay: Synthesis and
           cytotoxic potential investigation
    • Authors: Hasan Nasrabadi; Zahra Amirghofran, Ahmadreza Esmaeilbeig, Mehrangiz Bahrami, S. Jafar Hoseini
      Abstract: Stable water dispersion of Fe3O4 magnetic nanoparticles (NPs) were successfully synthesized by using 3-glycidoxypropyltrimethoxysilane (GPTMS) and Mg-phyllo (organo) silicate known as aminoclay (AC) containing pendant amino groups with the approximate composition (R8Si8Mg6O16(OH)4, R = CH2CH2CH2NH2). The Fe3O4-GPTMS magnetic NPs with an epoxy functional group are suitable for forming a covalent bond with the amine group of aminoclay in an epoxy ring opening reaction. Appropriate Fe3O4-GPTMS-aminoclay (FG-AC) magnetic composite are promising carriers for the targeting and delivery of platinum-based anticancer drugs. Analysis of the cytotoxicity of the nanostructures on a K562 leukemia cell line using a colorimetery assay shows that both the FG-AC and cis-platin/FG-AC magnetic composite were biocompatible. The nanostructures characterizations were investigated by Fourier transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy and energy dispersive analysis of X-ray techniques. Magnetic measurement revealed that the saturated magnetization of the FG-AC nanocomposite reached 7.6 emu/g and showed the characteristics of magnetism.An efficient method for producing stable water dispersion of magnetic Fe3O4 nanoparticles was reported which are promising carriers for the delivery of platinum-based anticancer drugs.
      PubDate: 2017-09-15T06:14:03.476112-05:
      DOI: 10.1002/aoc.4036
       
  • Isophorone-based organometallic chromophores: Synthesis, characterization
           and investigation of electro-optical properties
    • Authors: Keshvar Rahimpour; Reza Teimuri-Mofrad, Alireza Vaez
      Abstract: A series of hybrid donor–acceptor complexes with a ferrocene moiety and isophorone derivatives were synthesized. Data from 1H NMR, 13C NMR, Fourier transform infrared, atomic absorption and mass spectroscopies and CHN analysis supported the predicted structure of the products. A comparative investigation was performed using UV–visible, cyclic voltammetry and fluorescence measurements. Density functional theory was used to optimize the chromophore structure and calculation of highest occupied and lowest unoccupied molecular orbital energy levels. The ferrocene/isophorone hybrids show useful properties for further development and studies as electro-optic materials.A series of donor-acceptor complexes containing ferrocene and isophorone moieties were synthesized; 1H and 13C NMR, FT-IR, CHN analysis along with atomic absorption and mass spectroscopy supported the predicted structure of the products. Electronic and optical properties of these chromophores were studied by cyclic voltammetry, UV-Vis spectroscopy and fluorescents measurement. The quantum chemistry study was performed on synthesized compounds with the DFT approach. The B3LYP method and 6-31G (d) basis set were used for optimizing the structures in the gas-phase. The theoretical and experimental results show that these compounds can be considered as candidates in optical applications.
      PubDate: 2017-09-15T06:11:35.487392-05:
      DOI: 10.1002/aoc.4031
       
  • Sulfamic acid immobilized on amino-functionalized magnetic nanoparticles:
           A new and active magnetically recoverable catalyst for the synthesis of
           N-heterocyclic compounds
    • Authors: Lotfi Shiri; Hojatollah Narimani, Mosstafa Kazemi
      Abstract: Sulfamic acid immobilized on amino-functionalized magnetic nanoparticles (MNPs/DETA-SA) was successfully fabricated and characterized using various techniques. Diameters of approximately 15 nm for the MNPs/DETA-SA were observed from scanning electron microscopy images. The as-fabricated nanocomposite was applied as an efficient and magnetically reusable catalyst for the synthesis of 2,3-dihydroquinazoline-4(1H)-one and polyhydroquinoline derivatives. All products were obtained in good to excellent yields. Recovery tests confirm that the catalyst can be readily recovered using an external magnet and reused many times without significant loss of its catalytic activity.Sulfamic acid immobilized on amino-functionalized magnetic nanoperticles (MNPs/DETA-SA) was successfully fabricated and characterized by FT-IR, TGA, XRD, SEM and VSM spectroscopic techniques. As-fabricated nanocomposite was applied as an efficient and magnetically reusable catalyst for the synthesis of 2, 3-dihydroquinazoline-4(1H)-one and polyhydroquinoline derivatives. All products were obtained in good to excellent yields. Recovery tests confirm that the catalyst can be readily recovered by using an external magnet and reused many times without significant loss of its catalytic activity.
      PubDate: 2017-09-15T06:06:17.035271-05:
      DOI: 10.1002/aoc.3999
       
  • Co (II)-C12 alkyl carbon chain multi-functional ionic liquid immobilized
           on nano-SiO2 nano-SiO2@CoCl3-C12IL as an efficient cooperative catalyst
           for C–H activation by direct acylation of aryl halides with aldehydes
    • Authors: Yu Lin Hu; Ya Pan Wu, Ming Lu
      Abstract: Nano-silica supported ionic liquids composed of alkyl carbon chain and transition metal chlorides anions have been prepared and successfully applied as a heterogeneous catalyst in the direct aldehyde C-H activation. Catalytic results indicated that nano-SiO2 supported ionic liquid consisting C12 alkyl carbon chain and CoCl3 anion nano-SiO2@CoCl3-C12IL showed excellent catalytic properties with good to excellent yields towards the desired aryl ketones. The excellent recyclability of the supported catalyst, mild reaction conditions, low catalyst loading, and operational simplicity are the important features of this methodology.A novel and convenient procedure for the direct acylation of aryl halides with aldehydes to produce aryl ketones via the aldehyde C–H activation in the presences of nano-SiO2@CoCl3-C12IL catalyst has been developed.
      PubDate: 2017-09-15T06:01:46.550003-05:
      DOI: 10.1002/aoc.4096
       
  • Facile synthesis, characterisation and anti-inflammatory activities of
           ferrocenyl ester derivatives of 4-arylidene-5-imidazolinones
    • Authors: Dilip N. Shinde; Rajiv Trivedi, N. Vamsi Krishna, L. Giribabu, B. Sridhar, B.B. Rathod, R.S. Prakasham
      Abstract: This article describes the synthesis, optoelectronic properties and anti-inflammatory activities of a series of seven ferrocenyl ester-linked 4-arylidene-5-imidazolinone conjugates. Three different types of ortho-, meta- and para-substituted ferrocenyl esters have been prepared. Their UV–Vis spectra and electrochemical studies are described. The structure of one of the conjugates was confirmed by single-crystal X-ray diffraction study. These conjugates exhibited moderate anti-inflammatory activities.Ferrocenyl ester-linked 4-arylidene-5-imidazolinone conjugates have been synthesized and their optoelectronic and inflammatory activities are studied.
      PubDate: 2017-09-15T05:35:47.853568-05:
      DOI: 10.1002/aoc.4021
       
  • Mono- and tetranuclear copper(I) complexes with N-heterocyclic chelating
           and triphenylphosphine ligands: Crystal structures, luminescent and
           heterogeneous catalytic properties
    • Authors: Yuling Xu; Kesheng Shen, Shanshan Mao, Xinkui Shi, Huilu Wu, Xuyang Fan
      Abstract: N-heterocyclic chelating and triphenylphosphine ligands react with cuprous halide to form a variety of copper(I) complexes, namely, mononuclear [Cu(PBO)(PPh3)Br].CH2Cl2 (1) and [Cu(PBM)(PPh3)I] (2) (PBO = 2-(2′-Pyridyl)benzoxazole, PBM = 2-(2′-Pyridyl)benzimidazole, PPh3 = triphenylphosphine) and tetranuclear [Cu4(μ2-I)2(μ3-I)2(PPh3)4].2CH2Cl2 (3) have been synthesized and characterized. Complexes 1 and 2 are basically alike; both of them are mononuclear and four-coordinated, possessing a slightly distorted trigonal pyramidal geometry. Complex 3 is tetranuclear and the coordination numbers of the two copper(I) atoms are three and four, Cu(1) forming an approximate trigonal planar coordination environment, while Cu(2) is a slightly distorted trigonal pyramidal geometry, resulting in a distorted chair-like conformation. Complexes 1 and 2 are emissive in the solid state at ambient temperature, with the maxima at 552 and 602 nm, respectively, due to a MLCT excited state. Moreover, complex 3 manifests promising heterogeneous catalytic activities for the degradation of methylene blue (MB), with degradation efficiency of 99% under ambient light.Three new mono- and tetranuclear Cu(I) complexes have been synthesized and structurally characterized, which exhibit various architectures. Complexes 1 and 2 display interesting luminescent property. Complex 3 manifests promising catalytic activities for the degradation of methylene blue (MB), which degradation efficiency is 99%.
      PubDate: 2017-09-15T05:30:50.587154-05:
      DOI: 10.1002/aoc.4041
       
  • Amelioration of H4[W12SiO40] by nanomagnetic heterogenization: For the
           synthesis of 1H–pyrazolo[1,2-b]phthalazinedione derivatives
    • Authors: Priya Arora; Jaspreet Kaur Rajput
      Abstract: We conveniently coated silicotungstic acid (STA, H4[W12SiO40]) on amino-functionalized Si–magnetite nanoparticles, as surface functionalization of magnetic nanoparticles is an excellent way for green and efficient catalysis. The nanoparticles were structurally characterized using various techniques. The catalytic activity and recyclability of the STA–amine–Si–magnetite nanoparticles were probed through synthesis of 1H–pyrazolo[1,2-b]phthalazinedione derivatives. The reaction proceeds smoothly to provide products in excellent yields and short reaction times. The catalyst could be readily recovered using a simple external magnet and reused several times without any significant loss in activity. Herein, we report a comparison of the activity of H4[W12SiO40] as a homogeneous and heterogeneous catalyst, the latter being found to be more efficient. The findings offer effective methods for environmentally friendly synthesis of pyrazolo[1,2-b]phthalazinedione derivatives.The catalytic activity of a heteropoly acid i.e. silicotungstic acid has been drastically improved along with the ease of recyclability and reusability. Silicotungstic acid has been heterogenized by coating STA over amine functionalized Si-magnetite nanoparticles (STA-Amine-Si-Magnetite) and the catalytic activity has been tested by the synthesis of 1H-pyrazolo[1,2-b]phthalazinediones.
      PubDate: 2017-09-15T05:26:20.460377-05:
      DOI: 10.1002/aoc.4001
       
  • Synthesis of novel allyl palladium complexes bearing purine based NHC and
           a water soluble phosphine and their catalytic activity in the
           Suzuki-Miyaura coupling in water
    • Authors: Thomas Scattolin; Luciano Canovese, Fabiano Visentin, Stefano Paganelli, Patrizia Canton, Nicola Demitri
      Abstract: We have synthesized and fully characterized some novel allyl palladium complexes stabilized by mixed spectator ligands, namely the water soluble sodium 3,3′,3″-phosphinetriyltribenzenesulfonate, (TPPTS) and three carbenes derived from differently alkylated natural xanthines. In order to explore their potential applications we have tested their catalytic activity in the Suzuki-Miyaura coupling of para-bromoacetophenone with phenyl boronic acid, chosen as standard reaction. Only one of the complexes under study displays a remarkable stability in water and catalytic activity. We have therefore undertaken a catalytic investigation. These results are reported in the present paper together with the solid state structural characterization of a silver precursor of the palladium allyl complexes.The synthesis of three water soluble allyl palladium complexes bearing modified natural xantines and the sodium 3,3′,3″-phosphinetriyltribenzenesulfonate as spectator ligands, is reported. One among the ensuing complexes displays a reasonable catalytic activity toward the Suzuki-Miyaura reaction at moderate temperature. The catalytic study together with the solid state structure of one silver precursor is reported in the paper.
      PubDate: 2017-09-15T05:25:36.138506-05:
      DOI: 10.1002/aoc.4034
       
  • An expedient ‘click’ approach for the synthetic evaluation of
           ester-triazole-tethered organosilica conjugates
    • Authors: Gurjaspreet Singh; Sunita Rani
      Abstract: The present work articulates the synthesis of a new series of organo-functionalized triethoxysilanes derived from versatile carboxylic acids and 3-azidopropyltriethoxysilane in excellent yields. A proficient and convenient route implicating the Cu(I)-catalysed 1,3-cycloaddition of organic azide with terminal alkynes, labelled as click silylation, has been developed for the generation of ester-triazole-linked alkoxysilanyl scaffolds (4a–f). All the synthesized compounds have been thoroughly characterized using elemental analysis and Fourier transform infrared, 1H NMR and 13C NMR spectroscopic techniques. Importantly, the fabricated alkoxysilanes are potentially amenable for an in situ sol–gel condensation reaction with silica nanospheres leading to the incorporation of organic functionality via covalent grafting onto the nanostructured particle system. As a proof of concept, a one-pot preparation of organic–inorganic hybrid nanoparticles is presented using bis-silane 4 f. The efficiency and selectivity of the prepared nanocomposite towards metal ions is highlighted using adsorption experiments, and the immobilized nanoparticles present a high sensing efficiency towards Cu2+ and Pb2+ ions while demonstrating better response than that of the bulk material.New organo-functionalized triethoxysilanes (OfTES) derived from versatile carboxylic acids and 3-azidopropyltriethoxysilane (3-AzPTES) are reported. The derivatization of silica nanoparticles was carried out using one of the prepared silane to prepare organic-inorganic hybrid nanoparticles, which were utilized for the adsorptive removal of copper and lead ions.
      PubDate: 2017-09-15T05:21:30.253872-05:
      DOI: 10.1002/aoc.4028
       
  • Rhodium-catalyzed ortho-C-H olefination of aromatic aldehydes employing
           transient directing strategy
    • Authors: Xi Liu; Zhonghao Wang, Qun Chen, Ming-yang He, Liang Wang
      Abstract: A Rhodium(III)-catalyzed ortho-C-H olefination of aromatic aldehydes in the presence of catalytic amount of TsNH2 has been developed. The in situ generated imine intermediate from aldehyde and TsNH2 worked as a transient directing group. Both electron-rich and electron-deficient aromatic aldehydes were tolerated, affording the corresponding products in moderate to good yields. Importantly, the present protocol provides a straightforward access to olefinated aromatic aldehydes with aldehydes as the simple starting materials.A Rhodium(III)-catalyzed ortho-C-H olefination of aromatic aldehydes utilizing inexpensive TsNH2 as a transient directing group has been developed.
      PubDate: 2017-09-15T05:15:26.066973-05:
      DOI: 10.1002/aoc.4039
       
  • A pronounced ligand effect on platinum-catalyzed Hydrosilylation of
           terminal alkynes
    • Authors: Cheng Dong; Yang Yuan, Yu-Ming Cui, Zhan-Jiang Zheng, Jian Cao, Zheng Xu, Li-Wen Xu
      Abstract: The use of ligands to tune the reactivity and regioselectivity of transition metal-based catalyst for silicon-mediated organic synthesis (SiMOS) is an important topic and challenge in organosilicon chemistry and synthetic organic chemitstry. In this manuscript, the dual ligand platinum catalyst system was developed for the hydrosilylation of alkynes. It was found that regioselectivity enhancement was determined with combinational use of phosphine ligand (6a) and multifunctional Py-BINMOL ligand (4a). The corresponding vinylsilanes were obtained in high yields and high regioselectivities.Ligand Effect: It was found that the combinational use of multifunctional Py-BINMOL and amide-derived phosphine in platinum-catalyzed hydrosilylation of terminal alkyne could be applied in the enhancement of chemoselectivity of hydrosilylation.
      PubDate: 2017-09-15T05:10:56.971889-05:
      DOI: 10.1002/aoc.4037
       
  • Fe3O4@SiO2–ZrCl2-MNPs: A novel magnetic catalyst for the clean and
           efficient cascade synthesis of 1-(benzothiazolylamino)methyl-2-naphthol
           derivatives in the absence of solvent
    • Authors: Fatemeh Kamali; Farhad Shirini
      Abstract: A green, simple and eco-friendly three-component condensation for the synthesis of 1-(benzothiazolylamino)methyl-2-naphthols using new magnetic nanoparticles formulated as Fe3O4@SiO2–ZrCl2-MNPs is described. Considering the economic and environmental aspects, the method provides some advantages such as clean procedure, solvent-free conditions, simple operation and work-up, relatively short reaction times and high yields of the products. Moreover the introduced catalyst can be readily recovered up to 4 consecutive runs with consistent activity using an external magnet.A green, simple and eco-friendly three-component condensation for the synthesis of 1-(benzothiazolylamino)methyl-2-naphthols using new magnetic nanoparticles formulated as Fe3O4@SiO2–ZrCl2-MNPs is described.
      PubDate: 2017-09-11T03:00:44.345672-05:
      DOI: 10.1002/aoc.3972
       
  • Co(II) anchored glutaraldehyde crosslinked magnetic chitosan nanoparticles
           (MCS) for synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted
           imidazoles
    • Authors: Harminder Singh; Jaspreet Kaur Rajput
      Abstract: A simple, highly efficient and green synthesis of 2,4,5-trisubsituted and 1,2,4,5-tetrasubstituted imidazoles was developed using a novel MCS-GT@Co(II) magnetically recoverable and recyclable catalyst under refluxing conditions with ethanol as a solvent. The catalyst was prepared by immobilization of chitosan onto Fe3O4 using glutaraldehyde as crosslinker followed by Co(II) ion immobilization via cobalt acetate. The catalyst was characterized using various techniques. For organic products determination, 1H NMR, 13C NMR and Fourier transform infrared spectroscopies were used. The reaction was also tried with individual components of the catalyst, but the synergistic effect of the components in the prepared catalyst showed the highest yield and shortest reaction time.A green, novel and cost effective method of synthesis of MCS-GT-Co(II) nanoparticles is successfully developed and further they are used as a heterogeneous catalyst in the synthesis of tri and tetrasubstituted imidazoles. This method has advantages like short reaction time, high yield of product, simple work up, recyclable and reusable magnetic catalyst.
      PubDate: 2017-09-08T05:07:49.598563-05:
      DOI: 10.1002/aoc.3989
       
  • A simple, quick and novel protocol for biaryl synthesis using
           LiCl-promoted in situ-generated Pd nanoparticles
    • Authors: Parmita Phukan; Preeti Rekha Boruah, Praveen Singh Gehlot, Arvind Kumar, Diganta Sarma
      Abstract: This paper describes a simple and a very quick protocol for biaryl synthesis using the Suzuki–Miyaura cross-coupling reaction. A quintessential role of salting-out agent LiCl was observed in the Suzuki–Miyaura cross-coupling reaction that enhanced the reduction rate of Pd (II) to a considerable extent, resulting in the formation of nanosized palladium in a few seconds. The isolated Pd nanoparticles were characterized with X-ray diffraction, dynamic light scattering, TGA, transmission electron microscopy and scanning electron microscopy-dispersive X-ray spectroscopy. The Suzuki–Miyaura cross-coupling reaction proceeded very well with the in situ-generated Pd nanocatalysts furnishing the desired biaryl adducts with excellent yields.This paper describes a simple and a quick protocol for biaryl synthesis using Suzuki-Miyaura cross coupling reaction. A quintessential role of salting out agent LiCl was observed in the Suzuki-Miyaura cross-coupling reaction that enhanced the reduction rate of Pd (II) to a considerable extent affording nanosized palladium in a few seconds. The isolated Pd NPs were characterized with XRD, DLS, TGA, TEM, and SEM-EDX. Suzuki cross-coupling reaction proceeded very well with Pd-nano catalysts furnishing the desired biaryls with excellent yields.
      PubDate: 2017-09-05T23:01:31.115077-05:
      DOI: 10.1002/aoc.4009
       
  • Multifunctional triazolylferrocenyl Janus dendron: Nanoparticle
           stabilizer, smart drug carrier and supramolecular nanoreactor
    • Authors: Li Zhao; Qiangjun Ling, Xiong Liu, Chaodong Hang, Qiuxia Zhao, Fangfei Liu, Haibin Gu
      Abstract: Owing to their unique broken symmetry, amphiphilic Janus dendrimers and dendons provide fascinating properties for material, biological, pharmaceutical and biomedical applications. The integration of various organometallic moieties into these macromolecules will further offer the opportunity to form complex and intelligent architectures and materials. Here, we report a novel, simple and multifunctional Janus dendron containing redox-reversible hydrophobic ferrocene (Fc) unit, complexing-effective 1,2,3-triazole ligand and biocompatible hydrophilic triethylene glycol termini. Silver and gold nanoparticles were firstly successfully prepared by using the Janus dendron as the reducing agent of Au(III) and Ag(I), and the stabilizer of the corresponding nanoparticles. The redox response of the Fc moiety was then employed to trigger the release of model drug, rhodamine B, encapsulated in supramolecular micelles formed by the self-assembly of the Janus dendron. Finally, the precise and excellent metal-complexing ability of the triazole group in this dendron was fully utilized to stabilize a water-soluble Cu(I) catalyst, forming supramolecular nanoreactors for the catalysis of the copper(I)-catalyzed azide alkyne cycloaddition click reaction in only water. The multifunctional characteristics of this dendron highlight the potential for organometallic Janus dendrimers and dendrons in the fields of functional materials and nanomedicines.An amphiphilic triazolylferrocenyl Janus metallodendron with three PEG terminal was prepared and utilized as the reductant and stabilizer for silver and gold nanoparticles, drug carrier for redox-responsive controlled release, and supramolecular nanoreactor for copper(I)-catalyzed azide alkyne cycloaddition click reaction in only water.
      PubDate: 2017-09-05T22:56:28.473258-05:
      DOI: 10.1002/aoc.4000
       
  • Green synthesis of new pyrimido[4,5-d]pyrimidine derivatives using
           7-aminonaphthalene-1,3-disulfonic acid-functionalized magnetic Fe3O4@SiO2
           nanoparticles as catalyst
    • Authors: Ramin Ghorbani-Vaghei; Narges Sarmast
      Abstract: We, herein, describe a novel, simple, efficient and one-pot multi-component procedure for the synthesis of substituted pyrimido[4,5-d]pyrimidines via reaction of N,N-dimethyl-6-amino uracil, isothiocyanate and aromatic aldehydes promoted by 7-aminonaphthalene-1,3-disulfonic acid (ANDSA)-functionalized magnetic Fe3O4@SiO2 in water as solvent and without using any other harmful organic reagents. Compared with other reactions, using these organic–inorganic hybrid heterogeneous catalysts can help us to achieve a green procedure, high catalytic activity, easy recovery with an external magnetic field, and short reaction times.We describe a novel, efficient and one-pot multi-component procedure for the synthesis of substituted pyrimido[4,5-d]pyrimidines via reaction of N,N-dimethyl-6-amino uracil, isothiocyanate and aromatic aldehydes promoted by 7-aminonaphthalene-1,3-disulfonic acid (ANDSA)-functionalized magnetic Fe3O4@SiO2 in water as solvent and without using any other harmful organic reagents. Compared to other reactions, using these organic–inorganic hybrid heterogeneous catalysts can help us to achieve a green procedure, high catalytic activity, easy recovery and short reaction times.
      PubDate: 2017-09-05T22:55:55.085567-05:
      DOI: 10.1002/aoc.4003
       
  • Sonophotocatalytic treatment of diazinon using visible light-driven
           Ce:Cu-1,4-BDOAH2 photocatalyst in a batch-mode process: Response surface
           methodology and optimization
    • Authors: T. Taghipour; G.R. Karimipour, M. Ghaedi, M.R. Rahimi, S. Mosleh
      Abstract: Cu–1,4-benzenedioxyacetic acid (Cu-1,4-BDOAH2) with a narrow band gap (2.52 eV) was synthesized and doped with Ce to afford Ce:Cu-1,4-BDOAH2 as an efficient photocatalyst with narrower band gap (2.39 eV). The prepared Cu-1,4-BDOAH2 and Ce:Cu-1,4-BDOAH2 were characterized using Fourier transform infrared, energy-dispersive X-ray, diffuse reflectance spectroscopies, scanning electron microscopy and X-ray diffraction. The sonophotocatalytic degradation of diazinon was carried out in a batch-mode reactor using visible light-driven Ce:Cu-1,4-BDOAH2 photocatalyst as well as ultrasonic irradiation. The narrow band gap of the photocatalyst means that it can be activated under visible light illumination. The effects of operational parameters such as initial diazinon concentration (5–25 mg l−1), pH (2–10), photocatalyst dosage (10–30 mg) and irradiation time (10–30 min) on the sonophotocatalytic degradation efficiency were investigated using central composite design under response surface methodology. The optimization process was studied using desirability function and the results indicated 99.8% degradation, which was obtained at optimum values of 25 mg l−1, 6, 20 mg and 20 min for the initial concentration of diazinon, pH, photocatalyst dosage and irradiation time, respectively. Reusability experiments of Ce:Cu-1,4-BDOAH2 photocatalyst showed that it is quite stable with excellent catalytic activity even after five cycles.Cu-1,4-BDOAH2 was synthesized and doped with Ce to afford Ce:Cu-1,4-BDOAH2 as a new photocatalyst. Ce:Cu-1,4-BDOAH2 was used for sonophotocatalytic degradation of diazinon in a batch -mode reactor using visible light. The effects of operational parameters on the sonophotocatalytic degradation efficiency were investigated using central composite design under response surface methodology. The optimization process was studied using desirability function and the results indicated 99.8% degradation, which was obtained at optimal condition.
      PubDate: 2017-09-05T22:51:41.440295-05:
      DOI: 10.1002/aoc.3962
       
  • Application of the Fe3O4@1,10-phenanthroline-5,6-diol@Mn nano-catalyst for
           the green synthesis of tetrazoles and its biological performance
    • Authors: Davood Habibi; Somayyeh Heydari, Antonio Gil, Mina Afsharfarnia, Alireza Faraji, Roya Karamian, Mostafa Asadbegy
      Abstract: The Fe3O4 magnetic particles were modified with 1,10-phenanthroline-5,6-diol (Phen) and the related Mn complex (Fe3O4@Phen@Mn) synthesized as a heterogeneous catalyst to be used for the one-pot three-component synthesis of various tetrazoles. The catalysts were characterized by several methods, such as the elemental analysis, FT-IR, X-ray powder diffraction, dispersive X-ray spectroscopy, scanning electron microscopy, transmission electron microscopy, dynamic light scattering, thermogravimetric-differential thermal analysis, vibrating sample magnetometer and X-ray photoelectron spectroscopy. In addition, the antioxidant and antibacterial activities of the catalyst and its Phen ligand were in vitro screened with 2,2-diphenyl-1-picrylhydrazyl by free radical scavenging methods. Results showed that the synthesized compounds possess strong antioxidant activity (IC50; 0.172  ±  0.005 mg ml−1) as well as a good antibacterial potential in comparison to standards.The Fe3O4 magnetic particles were modified with 1,10-phenanthroline-5,6-diol and the related Mn complex synthesized as a heterogeneous catalyst to be used for the one-pot three component synthesis of various tetrazoles. The antioxidant and antibacterial activities of the catalyst and its Phen ligand were in vitro screened with 2,2-diphenyl-1-picrylhydrazyl (DPPH) by free radical scavenging methods. Results showed that the synthesized compounds possess strong antioxidant activity (IC50; 0.172 ± 0.005mg/ml) as well as a good antibacterial potential in comparison to standards.
      PubDate: 2017-09-05T22:46:21.967534-05:
      DOI: 10.1002/aoc.4005
       
  • Preparation and characterization of hexamethylenetetramine-functionalized
           magnetic nanoparticles and their application as novel catalyst for the
           synthesis of pyranopyrazole derivatives
    • Authors: Ramin Ghorbani-Vaghei; Vida Izadkhah
      Abstract: A new magnetic catalyst was prepared through the reaction of silanol groups, on the surface of silica-coated Fe3O4 magnetic nanoparticles, with (3-chloropropyl)triethoxysilane followed by hexamethylenetetramine and chlorosulfonic acid. The obtained magnetic catalyst was characterized using thermogravimetric analysis, vibrating sample magnetometry, scanning electron microscopy and energy-dispersive X-ray analysis. Its catalytic activity was investigated in the synthesis of pyranopyrazole compounds, and the results were excellent regarding high yield of the products and short reaction time.A new silica coated Fe3O4 MNPs was prepared and then functionalized with hexamethylenetetramine and chlorosulfonic acid. Then its catalytic activity was investigated in the synthesis of pyranopyrazole compounds.
      PubDate: 2017-09-05T22:46:10.162086-05:
      DOI: 10.1002/aoc.4025
       
  • DNA fastening and scission actions of Cu(II), Co(II), Ni(II) and Zn(II)
           complexes: synthesis, spectral characterization and cytotoxic study
    • Authors: Ganesan Kumaravel; Ponnukalai Ponya Utthra, Natarajan Raman
      Abstract: A heterocyclic compound, 2-(aminomethyl)benzimidazole dihydrohydrochloride, was treated with nitrobenzaldehyde to form a Schiff base that was made to react with divalent metals. A co-ligand, either 1,10-phenanthroline or 2,2′-bipyridine, was added to this mixture to obtain metal chelators of type [ML(co-L)2]Cl2. They were in 1:1:2 stoichiometry ratio, which was characterized by various spectroscopic techniques that suggested an octahedral geometry around the central metal ions. These complexes were investigated for their binding affinities with calf thymus (CT) DNA, using various techniques, such as UV–Vis, viscosity, cyclic voltammetry (CV), etc. The binding interaction studies revealed intercalation as the possible binding mode of the complexes with the CT DNA. In addition, these complexes were screened for their antimicrobial potential and DNA denaturing tendencies using gel electrophoretic assay. The antimicrobial screening investigation showed that the complexes behaved as better antimicrobial agents than the ligand, especially, complex 5 shows exceptional activity even in the electrophoretic assay along with the antimicrobial efficacy. Moreover, complex 5 was able to denature the plasmid DNA better than the other compounds. All the compounds were screened for cytotoxic efficacy, and the IC50 values suggest that the compounds possess cytotoxic activity to some extent that is almost the same as the activity of cisplatin.The DNA interactions exhibited by eight novel complexes, obtained from the Schiff base ligand [2-(aminomethyl)benzimidazole dihydrohydrochloride with nitrobenzaldehyde], metal salts and a coligand, either 1,10-phenanthroline or 2,2′-bipyridine, suggest that they are good metallointercalators. The binding interaction studies revealed intercalation as the possible binding mode of the complexes with the CT DNA. Their various characteristics were explored where the complexes manifested as excellent antimicrobial agents. The IC50 values suggest that the synthesized compounds possess almost same cytotoxic activity compared to cisplatin.
      PubDate: 2017-09-05T22:41:05.900549-05:
      DOI: 10.1002/aoc.4010
       
  • Tungstate supported mesoporous silica SBA-15 with imidazolium framework as
           a hybrid nanocatalyst for selective oxidation of sulfides in the presence
           of hydrogen peroxide
    • Authors: Alireza Sedrpoushan; Fereshteh Hosseini-Eshbala, Farajollah Mohanazadeh, Masoud Heydari
      Abstract: In this work, a new heterogeneous catalyst (SBA-15/Im/WO42−) was prepared, and then its performance in the oxidation of organic sulfides was studied (using 30% H2O2 as green oxidant under neutral reaction conditions). This organic–inorganic hybrid mesoporous material was characterized by various techniques, such as FT-IR, inductively coupled plasma, X-ray powder diffraction, high-resolution-transmission electron microscopy, N2 adsorption–desorption and thermogravimetric analysis. The catalyst was also applied to the selective oxidation of various sulfides. The hybrid catalyst was easily recovered, and was very stable and retained good activity for at least five successive runs without any additional activation. Moreover, there was no remarkable decrease in the activity and selectivity of the catalyst. The products could be easily isolated by just removing the solvent after filtering the catalyst. The yields of the catalytic productions through this catalyst were in the range from 75% to 97%.A new heterogeneous catalyst (SBA-15/Im/WO42−) was prepared and then, its performance for the oxidation of organic sulfides was studied (using 30% H2O2 as green oxidant under neutral reaction conditions). The hybrid catalyst was easily recovered and been very stable, and retained good activity for at least 5 successive runs without any additional activation. The products could be easily isolated by just removing the solvent after filtering the catalyst.
      PubDate: 2017-08-31T06:27:23.689196-05:
      DOI: 10.1002/aoc.4004
       
  • Iminophosphine palladium catalysts for Suzuki carbonylative coupling
           reaction
    • Authors: Mustafa Kemal Yılmaz; Hülya Keleş, Simay İnce, Mustafa Keleş
      Abstract: Three iminophosphine ligands having soft phosphorus and hard nitrogen atoms and their Pd(II) complexes were synthesized and characterized using 1H NMR, 13C NMR, 31P NMR and Fourier transform infrared spectroscopic techniques. Also, electrochemical properties of the iminophosphines and their Pd(II) complexes were investigated in acetonitrile–tetrabutylammonium perchlorate solution with cyclic and square wave voltammetry techniques. All Pd(II) complexes were evaluated as catalysts for carbonylative cross-coupling reactions of aryl iodides with phenylboronic acid. The Suzuki carbonylation of aryl iodides at 80 °C under balloon pressure of carbon monoxide in the presence of K2CO3 as a base was examined, and good to high conversions and excellent selectivities were obtained.Three iminophosphine ligands and their Pd(II) complexes were synthesized and characterized. Electrochemical properties of the iminophosphines and their Pd(II) complexes were investigated in acetonitrile–tetrabutylammonium perchlorate solution with cyclic and square wave voltammetry techniques. All Pd(II) complexes were evaluated as catalysts for carbonylative coupling reactions of aryl iodides with phenylboronic acid at 80 °C under balloon pressure of carbon monoxide in the presence of K2CO3 as a base and good to high conversions and excellent selectivities were obtained.
      PubDate: 2017-08-31T06:21:18.330939-05:
      DOI: 10.1002/aoc.4002
       
  • Preparation of an organic–inorganic hybrid based on synergy of Brønsted
           and Lewis acid centres as heterogeneous magnetic nanocatalyst for
           ultrafast synthesis of acetaminophen
    • Authors: M. Kooti; E. Nasiri
      Abstract: A heterogeneous nanocatalyst based on a Cu(II) complex containing phosphotungstic acid and N/O-donor ligands supported on cobalt ferrite nanoparticles was successfully prepared. The synthesized nanocatalyst was characterized using various techniques. The magnetic nanocatalyst was examined as an efficient and synergistic catalyst for ultrafast synthesis of acetaminophen at room temperature and under solventless conditions. The examined synergistic nanocatalyst, which has both Lewis and Brønsted acidic sites, could be easily separated from the reaction system and reused several times without significant loss of its activity. The synthesized acetaminophen was also fully characterized.A novel copper complex with phosphotungstic acid and N/O donor ligands was supported on cobalt ferrite NPs and used as efficient catalyst for ultrafast synthesis of acetaminophen. Both the catalyst and acetaminophen have been fully ccharacterized.The nanocatalyst could be easily recovered and reused for several times without loss of its activity.
      PubDate: 2017-08-31T06:17:19.926032-05:
      DOI: 10.1002/aoc.3990
       
  • Synthesis of pyranopyrazoles using
           nano-Fe-[phenylsalicylaldiminemethylpyranopyrazole]Cl2 as a new Schiff
           base complex and catalyst
    • Authors: Ahmad Reza Moosavi-Zare; Hamid Goudarziafshar, Khadijeh Saki
      Abstract: By the condensation reaction of benzaldehyde with ethyl acetoacetate, malononitrile and hydrazine hydrate in the presence of FeCl2, a pyranopyrazole derivative was prepared which was then reacted with salicylaldehyde to afford nano-Fe-[phenylsalicylaldiminemethylpyranopyrazole]Cl2 (nano-[Fe-PSMP]Cl2). The prepared nano-Schiff base complex was fully characterized using Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, differential thermogravimetry, scanning electron microscopy and UV–visible spectroscopy, and was used as an efficient and catalyst for the preparation of pyranopyrazoles.Nano-Fe-[phenyl-salicylaldimine-methylpyranopyrazole]Cl2 as a new nano-Schiff base complex and catalyst was prepared, identified and applied for the preparation of pyranopyrazoles.
      PubDate: 2017-08-25T06:20:45.297416-05:
      DOI: 10.1002/aoc.3968
       
  • A tridentate CNO-donor palladium(II) complex as efficient catalyst for
           direct C―H arylation: Application in preparation of imidazole-based
           push–pull chromophores
    • Authors: Hui-Hong Li; Ratnava Maitra, Ya-Ting Kuo, Jie-Hong Chen, Ching-Han Hu, Hon Man Lee
      Abstract: A series of imidazolium chlorides for the formation of tridentate CNO-donor palladium(II) complexes featuring N-heterocyclic carbene moieties have been developed from cheap and readily available starting materials with high yields. Their palladium complexes were prepared by reactions between the ligand precursors and PdCl2 using K2CO3 as base in pyridine with reasonable yields. These air-stable metal complexes were characterized using 1H NMR and 13C{1H} NMR spectroscopy and elemental analyses. Heteronuclear multiple bond correlation experiments were performed to identify key NMR signals of these compounds. The structures of two of the complexes were also established by single-crystal X-ray diffraction analysis. One of these complexes was successfully applied in the direct C―H functionalization reactions between heterocyclic compounds and aryl bromides, producing excellent yields of coupled products. The coupling reactions were scalable, allowing grams of coupled products to be obtained with a mere 2 mol% of Pd loading. The catalyst system developed allowed the large-scale preparation of several push–pull chromophores straightforwardly. Photophysical properties based on UV–visible and fluorescence spectroscopy for these chromophores were investigated. Deep blue photoluminescence with moderate quantum efficiency and twisted intramolecular charge transfer excited state were observed for these chromophores. Density functional theory (DFT) and time-dependent DFT calculations were performed to support the experimental results.A tridentate CNO-donor palladium(II) complex featuring an N-heterocyclic carbene moiety was developed as an efficient catalyst for direct C―H arylation between heterocyclic compounds and aryl bromides. The catalyst system allowed large-scale preparation of several push–pull chromophores straightforwardly with a mere 2 mol% of Pd loading.
      PubDate: 2017-08-25T05:32:15.586936-05:
      DOI: 10.1002/aoc.3956
       
  • Selective detection of Hg2+ ion in aqueous medium with the use of
           3-(pyrimidin-2-ylimino)indolin-2-one-functionalized SBA-15
    • Authors: Negar Lashgari; Alireza Badiei, Ghodsi Mohammadi Ziarani
      Abstract: An isatin-based fluorophore, 3-(pyrimidin-2-ylimino)indolin-2-one, was grafted on a large-pore mesoporous silica material (SBA-15) via a two-step modification process. The obtained material (SBA-Is-Py) was characterized using various techniques and the characterization showed that the ordered porous structure was preserved after the post-grafting procedure. The optical sensing ability of SBA-Is-Py was studied upon the addition of a variety of metal ions and a marked fluorescence quenching by Hg2+ ion was observed. SBA-Is-Py exhibited excellent Hg2+-specific luminescence quenching over various competing cations. Furthermore, linear changes of the optical properties of SBA-Is-Py as a function of the concentrations of Hg2+ ion were found, with a calculated detection limit of 3.28 × 10−7 M. In addition, SBA-Is-Py was successfully employed for the determination of Hg2+ in real water samples.An isatin based fluorophore, (3-(pyrimidin-2-ylimino)indolin-2-one), was grafted on a mesoporous silica material (SBA-15) via a two-step modification process. The optical sensing ability of SBA-Is-Py was studied upon the addition of a variety of metal ions and a remarkable fluorescence quenching by Hg2+ ion was observed. SBA-Is-Py exhibited excellent Hg2+-specific luminescence quenching over various competitive cations. Furthermore, linear changes of the optical properties of SBA-Is-Py as a function of the concentrations of Hg2+ ion were proved.
      PubDate: 2017-08-25T05:21:39.004327-05:
      DOI: 10.1002/aoc.3991
       
  • Synthesis, characterization and electrocatalytic performance of a
           dinuclear triazenidosilver(I) complex for hydrogen production
    • Authors: Dan Xue; Su-Ping Luo, Shu-Zhong Zhan
      Abstract: Our group has developed a series of molecular electrocatalysts for hydrogen generation based on triazenido–metal complexes (cobalt, copper, etc.). In this paper, we first present the electrocatalytic performance of a new dinuclear silver complex, [Ag2(L)2], formed by the reaction of the triazenido ligand 1-[(2-carboxymethyl)benzene]-3-[(2-methoxy)benzene]triazene (HL) with AgNO3. At room temperature, the silver complex shows photoluminescence at 653 nm. The electrocatalytic systems based on this silver complex can afford 106.57 and 1536.36 moles of hydrogen per mole of catalyst per hour from acetic acid at an overpotential (OP) of 991.6 mV and from a neutral aqueous buffer (pH = 7.0) at an OP of 837.6 mV, respectively. Electrochemical investigations show that both silver ion and triazenido ligand play a role in determining the catalytic activities of the electrocatalytic system.The reaction of 1-[(2-carboxymethyl)benzene]-3-[(2-methoxy)benzene]triazene (HL) with AgNO3 affords a silver complex, [Ag2(L)2], a new electrocatalyst for hydrogen evolution from both acetic acid and water.
      PubDate: 2017-08-25T05:17:21.842298-05:
      DOI: 10.1002/aoc.3997
       
  • Ferrocene-tagged ionic liquid stabilized on silica-coated magnetic
           nanoparticles: Efficient catalyst for the synthesis of
           2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions
    • Authors: Reza Teimuri-Mofrad; Mahdi Gholamhosseini-Nazari, Elmira Payami, Somayeh Esmati
      Abstract: An advanced novel magnetic ionic liquid based on imidazolium tagged with ferrocene, a supported ionic liquid, is introduced as a recyclable heterogeneous catalyst. Catalytic activity of the novel nanocatalyst was investigated in one-pot three-component reactions of various aldehydes, malononitrile and 2-naphthol for the facile synthesis of 2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions without additional co-catalyst or additive in air. For this purpose, we firstly synthesized and investigated 1-(4-ferrocenylbutyl)-3-methylimidazolium acetate, [FcBuMeIm][OAc], as a novel basic ferrocene-tagged ionic liquid. This ferrocene-tagged ionic liquid was then linked to silica-coated nano-Fe3O4 to afford a novel heterogeneous magnetic nanocatalyst, namely [Fe3O4@SiO2@Im-Fc][OAc]. The synthesized novel catalyst was characterized using 1H NMR, 13C NMR, Fourier transform infrared and energy-dispersive X-ray spectroscopies, X-ray diffraction, and transmission and field emission scanning electron microscopies. Combination of some unique characteristics of ferrocene and the supported ionic liquid developed the catalytic activity in a simple, efficient, green and eco-friendly protocol. The catalyst could be reused several times without loss of activity.An advanced novel magnetic ionic liquid based on imidazolium tagged with ferrocene was designed and synthesized as a recyclable heterogeneous catalyst. The activity of the nanocatalyst was investigated for the facile synthesis of 2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions.
      PubDate: 2017-08-25T05:15:55.189493-05:
      DOI: 10.1002/aoc.3955
       
  • Nitro group reduction and Suzuki reaction catalysed by palladium supported
           on magnetic nanoparticles modified with carbon quantum dots generated from
           glycerol and urea
    • Authors: Mohammad Gholinejad; Fatemeh Zareh, Carmen Nájera
      Abstract: Glycerol and urea were used as green and cheap sources of carbon quantum dots (CQD) for modifying Fe3O4 nanoparticles (NPs). The obtained CQD@Fe3O4 NPs were used for the stabilization of palladium species and the prepared catalyst, Pd@CQD@Fe3O4, was characterized using various techniques. This magnetic supported palladium was applied as an efficient catalyst for the reduction of aromatic nitro compounds to primary amines at room temperature using very low palladium loading (0.008 mol%) and also for the Suzuki–Miyaura cross-coupling reaction of aryl halides as well as challenging heteroaryl bromides and aryl diazonium salts with arylboronic acids and with potassium phenyltrifluoroborate. This magnetically recyclable catalyst was recovered and reused for seven consecutive runs in the reduction of 4-nitrotoluene to p-toluidine and for ten consecutive runs in the reaction of 4-iodoanisole with phenylboronic acid with small decrease of activity. The catalyst reused in the Suzuki reaction was characterized using transmission electron microscopy, vibrating sample magnetometry and X-ray photoelectron spectroscopy. Using experiments such as hot filtration and poisoning tests, it has been shown that the true catalyst works under homogeneous conditions according to the release–return pathway of active palladium species.A new sustainable magnetic carbon quantum dot-supported palladium catalyst was prepared and applied in reduction and Suzuki reactions.
      PubDate: 2017-08-25T05:11:46.819238-05:
      DOI: 10.1002/aoc.3984
       
  • Suzuki–Miyaura coupling reaction in water in the presence of robust
           palladium immobilized on modified magnetic Fe3O4 nanoparticles as a
           recoverable catalyst
    • Authors: Arefeh Dadras; M. Reza Naimi-Jamal, Firouz Matloubi Moghaddam, Seyed Ebrahim Ayati
      Abstract: Aryl halides and especially inactive aryl chlorides were coupled to benzenoid aromatic rings in a Suzuki–Miyaura coupling reaction in the absence of organic solvents and toxic phosphine ligands. The reaction was catalysed by a recoverable magnetic nanocatalyst, Pd@Fe3O4, in aqueous media. This method is green, and the catalyst is easily removed from the reaction media using an external magnetic field and can be re-used at least 10 times without any considerable loss in its activity. The catalyst was characterized using scanning and transmission electron microscopies, thermogravimetric analysis, inductively coupled plasma spectroscopy, Fourier transform infrared spectroscopy, CHN analysis, X-ray diffraction and vibrating sample magnetometry.Biaryl compounds were synthesized in water as a green medium via Suzuki–Miyaura coupling reaction of aryl halides and phenylboronic acid using palladium immobilized on modified Fe3O4 magnetic nanoparticles. The catalyst can be easily separated from reaction media and is useable for more than 10 times without reduction in its activity.
      PubDate: 2017-08-25T05:05:53.38195-05:0
      DOI: 10.1002/aoc.3993
       
  • Application of novel copper organic material for facile microextraction of
           sodium valproate from human plasma samples: Experimental design
           optimization and isotherm study
    • Authors: Sonia Bahrani; Mehrorang Ghaedi, Tahere Taghipour, Mohammad Javad Khoshnood Mansoorkhani, Ahmad Reza Bagheri, Abbas Ostovan
      Abstract: Well-designed metal organic materials (MOMs) were synthesized and applied for pre-concentration and determination of sodium valproate (Na-VP) from biological samples, bound to the copper complex of 1,4-phenylenedioxydiacetic acid under mild conditions. The channels of this sorbent provide high efficiency and also selectivity. The MOMs were structurally characterized using Fourier transform infrared and energy-dispersive X-ray spectroscopies, scanning electron microscopy and X-ray diffraction, and they were found to have suitable features for quantification of Na-VP using HPLC coupled with UV detection at λ = 215 nm. Moreover, the rate of adsorption is improved by ultrasonic power and the experimental data are best fitted according to Freundlich adsorption isotherm. According to the central composite design, the best experimental conditions are 280.0 μl, 3.0 min and 17.0 mg for volume of eluent, sonication time and sorbent mass respectively. Calibration plots show linear responses towards Na-VP concentrations (0.4–18.0 μg ml−1), satisfactory limit of detection (0.06 μg ml−1, S/N = 3) and reasonable enrichment factor (70.58). The coefficient of variation values of both inter- and intra-day analyses were less than 4.0%, indicating a candidate method for the determination of Na-VP in human plasma with reasonable recovery and efficiency.Well-designed metal organic materials (MOMs) were synthesized and applied for pre-concentration and determination of sodium valproate (Na-VP) from biological samples, bound to the copper complex of 1,4-phenylenedioxydiacetic acid under mild conditions. The channels of this sorbent provide high efficiency and also selectivity.
      PubDate: 2017-08-25T05:00:41.624639-05:
      DOI: 10.1002/aoc.3960
       
  • Preparation of Fe3O4@5,10-dihydropyrido[2,3-b]quinoxaline-7,8-diol copper
           complex: A capable nanocatalyst for the green synthesis of 1-substituted
           1H-tetrazoles
    • Authors: Davood Habibi; Narges Pakravan, Ameneh Arabi, Zahra Kaboudvand
      Abstract: Fe3O4 magnetic nanoparticles functionalized with 5,10-dihydropyrido[2,3-b]quinoxaline-7,8-diol were synthesized as was their complex with copper as a novel nanomagnetic iron oxide catalyst via a simple and green method, and characterized using various techniques. The capability of the catalyst was evaluated in the one-pot three-component synthesis of different tetrazoles, which showed very good results. Mild reaction conditions, good reusability and simple magnetic work-up make this methodology interesting for the efficient synthesis of tetrazoles.Fe3O4 magnetic nanoparticles functionalized with 5,10-dihydropyrido[2,3-b] quinoxaline-7,8-diol were synthesized as was their complex with copper as a novel nanomagnetic iron oxide catalyst via a simple and green method. The capability of the catalyst was evaluatedin the one-pot three-component synthesis of different tetrazoles, which showed very good results.
      PubDate: 2017-08-25T04:55:54.842524-05:
      DOI: 10.1002/aoc.3988
       
  • Synthesis, crystal structures and DNA/human serum albumin binding of
           ternary Cu(II) complexes containing amino acids and
           6-(pyrazin-2-yl)-1,3,5-triazine-2,4-diamino
    • Authors: Chun-Lian Zhang; Xue-Mei Zhang, Wei Liu, Shi Chen, Zong-Wan Mao, Xue-Yi Le
      Abstract: Two water-soluble 6-(pyrazin-2-yl)-1,3,5-triazine-2,4-diamino (pzta)-based Cu(II) complexes, namely [Cu(l-Val)(pzta)(H2O)]ClO4 (1) and [Cu(l-Thr)(pzta)(H2O)]ClO4 (2) (l-Val: l-valinate; l-Thr: l-threoninate), were synthesized and characterized using elemental analyses, molar conductance measurements, spectroscopic methods and single-crystal X-ray diffraction. The results indicated that the molecular structures of the complexes are five-coordinated and show a distorted square-pyramidal geometry, in which the central copper ions are coordinated to N,N atoms of pzta and N,O atoms of amino acids. The interactions of the complexes with DNA were investigated using electronic absorption, competitive fluorescence titration, circular dichroism and viscosity measurements. These studies confirmed that the complexes bind to DNA through a groove binding mode with certain affinities (Kb = 4.71 × 103 and 1.98 × 103 M−1 for 1 and 2, respectively). The human serum albumin (HSA) binding properties of the complexes were also evaluated using fluorescence and synchronous fluorescence spectroscopies, indicating that the complexes could quench the intrinsic fluorescence of HSA in a static quenching process. The relevant thermodynamic parameters revealed the involvement of van der Waals forces and hydrogen bonds in the formation of complex–HSA systems. Finally, molecular docking technology was also used to further verify the interactions of the complexes with DNA/HSA.6-(Pyrazin-2-yl)-1,3,5-triazine-2,4-diamino (pzta)-based Cu(II) complexes with amino acids, [Cu(l-Val)(pzta)(H2O)]ClO4 (1) and [Cu(l-Thr)(pzta)(H2O)]ClO4 (2), were synthesized. The DNA/human serum albumin (HSA) binding properties of the complexes were explored using spectroscopic and viscometric measurement methods, and the binding modes or sites were further confirmed using molecular docking technology.
      PubDate: 2017-08-22T04:33:08.525963-05:
      DOI: 10.1002/aoc.3994
       
  • Facile fabrication of ZnO/N-doped helical carbon nanotubes composites with
           enhanced photocatalytic activity toward organic pollutant degradation
    • Authors: Shuaishuai Ma; Qing Li, Zhilan Cai, Zhaolian Ye, Yuming Zhou
      Abstract: Novel ZnO/N-doped helical carbon nanotubes (ZnO/N-HCNTs) composites were successfully synthesized via a facile chemical precipitation approach at room temperature. The sample was well characterized by X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM) and ultraviolet–visible diffuse reflectance spectroscopy (UV–vis DRS). The photocatalytic activity was evaluated in the degradation of methylene blue (MB) aqueous solution under UV light irradiation. It is found that ZnO nanoparticles were highly and uniformly anchored on the surface and inner tubes of the N-HCNTs with size of about 5 nm, and significantly enhanced the photocatalytic activity compared to pure ZnO. The enhanced photocatalytic activity of ZnO/N-HCNTs composites can be ascribed to the integrative synergistic effect of effective interfacial hybridization between N-HCNTs and ZnO nanoparticles and the prolonged lifetime of photogenerated electron–hole pairs. Moreover, the ZnO/N-HCNTs could be easily recycled without any obvious decrease in photocatalytic activity and could be promote their application in the area of environmental remediation.Novel ZnO/N-doped helical carbon nanotubes (ZnO/N-HCNTs) composites were successfully synthesized via a facile chemical precipitation approach at room temperature. It is found that ZnO nanoparticles were highly and uniformly anchored on the surface and inner tubes of the N-HCNTs with size of about 5 nm, and significantly enhanced the photocatalytic activity compared to pure ZnO.
      PubDate: 2017-08-22T04:31:56.537994-05:
      DOI: 10.1002/aoc.3966
       
  • Novel ionic liquid supported on Fe3O4 nanoparticles as an efficient
           catalyst for the synthesis of new chromenes
    • Authors: Javad Safaei-Ghomi; Fahime Eshteghal, Hossein Shahbazi-Alavi
      Abstract: An efficient procedure for the synthesis of new chromenes by the multicomponent reaction of aldehydes, 4-hydroxycoumarin and 2-hydroxynaphthalene-1,4-dione in the presence of an ionic liquid supported on Fe3O4 nanoparticles is described. The ionic liquid supported on Fe3O4 nanoparticles as a magnetic catalyst gives products in high yields. Significant features of this method are: short reaction times, excellent yields, green method and use of an effective catalyst that can be recovered and reused many times without loss of its catalytic activity.A novel ionic liquid (IL) supported on Fe3O4 magnetic nanoparticles (MNPs) has been successfully prepared and characterized. These MNPs were used as an efficient heterogeneous catalyst for the one-pot three-component synthesis of new chromenes in ethanol–water at 50 °C.
      PubDate: 2017-08-22T04:31:32.629377-05:
      DOI: 10.1002/aoc.3987
       
  • Excellent alkene epoxidation catalytic activity of macrocyclic-based
           complex of dioxo-Mo(VI) on supermagnetic separable nanocatalyst
    • Authors: Fatemeh Payami; Abolfazl Bezaatpour, Habibollah Eskandari
      Abstract: A phenoxybutane-based Schiff base complex of cis-dioxo-Mo(VI) was supported on paramagnetic nanoparticles and characterized using powder X-ray diffraction, infrared, diffuse reflectance and atomic absorption spectroscopies, scanning and transmission electron microscopies and vibrating sample magnetometry. The separable nanocatalyst was tested for the selective epoxidation of cyclohexene, cyclooctene, styrene, indene, α-pinene, 1-octene, 1-heptene, 1-dodecene and trans-stilbene using tert-butyl hydroperoxide (80% in di-tert-butyl peroxide–water, 3:2) as oxidant in chloroform. The catalyst was efficient for oxidation of cyclooctene with 100% selectivity for epoxidation with 98% conversion in 10 min. We were able to separate magnetically the nanocatalyst using an external magnetic field and used the catalyst at least six successive times without significant decrease in conversion. The turnover frequency of the catalyst was remarkable (2556 h−1 for cyclooctene). The proposed nanomagnetic catalyst has advantages in terms of catalytic activity, selectivity, catalytic reaction time and reusability by easy separation.Phenoxy butane based Schiff base complex of Cis-dioxo-Mo(VI) was supported on nanoparticles and characterized by physico-chemical spectroscopy. The catalyst was tested for the selective epoxidation of olefins using TBHP in chloroform. This catalyst is efficient for oxidation of cyclooctene with 100% selectivity for epoxidation with 98% conversion in 10 min. The turn over frequency of catalyst is so remarkable (2556 h−1 for cyclooctene).
      PubDate: 2017-08-22T04:25:53.747807-05:
      DOI: 10.1002/aoc.3986
       
  • Chemo-selective reduction of nitro and nitrile compounds using Ni
           nanoparticles immobilized on hyperbranched polymer-functionalized magnetic
           nanoparticles
    • Authors: Seyed Jamal Tabatabaei Rezaei; Asemeh Mashhadi Malekzadeh, Sima Poulaei, Ali Ramazani, Hossein Khorramabadi
      Abstract: The nitro and nitrile groups in aromatic and aliphatic compounds containing various reducible substituents such as carboxylic acid, ketone, aldehyde and halogen are selectively reduced to the corresponding amines in water as a green solvent with excellent yields by employing NaBH4 in the presence of Fe3O4@PAMAM/Ni(0)-b-PEG nanocatalyst. The morphology and structural features of the catalyst were characterized using various microscopic and spectroscopic techniques. The designed catalyst system because of it being covered with hydrophilic polymers is soluble in a wide range of solvents (e.g. water and ethanol) and suitable for immobilizing and stabilizing Ni nanoparticles in aqueous mediums. In addition, the catalyst can be easily recovered from a reaction mixture by applying an external magnetic field and can be reused up to six runs without significant loss of activity.We have developed a novel magnetically recoverable nickel-based semi-heterogeneous catalytic system (Fe3O4@PAMAM/Ni(0)-b-PEG) for the selective reduction of nitro and nitrile groups in aromatic and aliphatic compounds containing various reducible substituents to the corresponding amines in water as a green solvent.
      PubDate: 2017-08-22T04:20:48.122997-05:
      DOI: 10.1002/aoc.3975
       
  • Porphyrin-based polymer-supported palladium as an excellent and recyclable
           catalyst for Suzuki–Miyaura coupling reaction in water
    • Authors: Jian Chen; Ju Zhang, Dajian Zhu, Tao Li
      Abstract: A porphyrin-based polymer with high surface area was synthesized using 5,10,15,20-tetraphenylporphyrin through a one-pot Friedel–Crafts alkylation reaction. Pd(II) was successfully supported on this polymer. This strategy provides an easy approach to produce highly stable Pd–porphyrin-based polymer. The resulting Pd catalyst was characterized using Fourier transform infrared and X-ray photoelectron spectroscopies, thermogravimetric analysis, scanning and transmission electron microscopies and N2 adsorption–desorption measurements. This porphyrin-based polymer-supported Pd was used as a heterogeneous catalyst for Suzuki–Miyaura coupling reaction in water. The results demonstrated that this Pd catalyst indeed exhibited excellent catalytic activity and recycling performance in water, even for inactive aryl chloride substrate. A new heterogeneous strategy for catalyzing the Suzuki–Miyaura reaction in water is provided.A porphyrin-based polymer-supported Pd catalyst is reported for Suzuki–Miyaura coupling reactions in water.
      PubDate: 2017-08-22T04:16:43.435479-05:
      DOI: 10.1002/aoc.3996
       
  • Copper containing nanosilica thioalated dendritic material: A recyclable
           catalyst for synthesis of benzimidazoles and benzothiazoles
    • Authors: Maryam Zakeri; Majid Moghadam, Valiollah Mirkhani, Shahram Tangestaninejad, Iraj Mohammadpoor-Baltork, Zari Pahlevanneshan
      Abstract: In this paper, the design and characterization of a new heterogeneous catalyst by incorporation of copper ions into the nanosilica modified by thiole–based dendrimer are reported. The prepared catalyst was characterized by FT–IR, TGA, elemental analysis, FE–SEM, TEM, XPS and ICP–OES techniques. This material was used as catalyst in the synthesis benzimidazoles and benzothiazoles by the reaction of substituted benzaldehydes with 1,2–diaminobenzene or 2–aminothiophenol, respectively. The advantages of the present catalytic system are high yields, mild conditions and short reaction times. On the other hand, this new synthesized catalyst was recycled very well and reused several times without significant loss of its catalytic activity.The synthesis and characterization of Cu(II) containing thiolated dendrimer on nanosilica have been described. The prepared catalyst was characterized by FT-IR, UV–Vis, TGA, elemental analysis, ICP-OES, TEM, FE-SEM and XPS techniques. The Cu(II)-TD@nSiO2 has been used as an efficient catalyst for the preparation of various benzimidazoles and benzothiazoles under mild conditions. Furthermore, the catalyst is stable under the reaction conditions and can be recycled and reused several times without a significant loss in activity.
      PubDate: 2017-08-22T04:15:41.044032-05:
      DOI: 10.1002/aoc.3937
       
  • Highly efficient oxidative cleavage of alkenes and cyanosilylation of
           aldehydes catalysed by magnetically recoverable MIL-101
    • Authors: Maryam Nourian; Farnaz Zadehahmadi, Reihaneh Kardanpour, Shahram Tangestaninejad, Majid Moghadam, Valiollah Mirkhani, Iraj Mohammadpoor-Baltork
      Abstract: The catalytic activity of magnetically recoverable MIL-101 was investigated in the oxidation of alkenes to carboxylic acids and cyanosilylation of aldehydes. MIL-101 was treated with Fe3O4 and the prepared catalyst was characterized using Fourier transform infrared spectroscopy, X-ray diffraction, N2 adsorption measurements, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy and inductively coupled plasma analysis. The catalytic active sites in this heterogeneous catalyst are Cr3+ nodes of the MIL-101 framework. This heterogeneous catalyst has the advantages of excellent yields, short reaction times and reusability several times without significant decrease in its initial activity and stability in both oxidation and cyanosilylation reactions. Its magnetic property allows its easy separation using an external magnetic field.Magnetically recoverable catalysts are of great interest. In this paper, the catalytic activity of magnetically recoverable MIL-101 was investigated in the oxidation of alkenes to carboxylic acids and cyanosilylation of aldehydes.
      PubDate: 2017-08-22T04:10:55.051425-05:
      DOI: 10.1002/aoc.3957
       
  • Oxidation reactions catalysed by molybdenum(VI) complexes grafted on
           UiO-66 metal–organic framework as an elegant nanoreactor
    • Authors: Niloufar Afzali; Shahram Tangestaninejad, Majid Moghadam, Valiollah Mirkhani, Adam Mechler, Iraj Mohammadpoor-Baltork, Reihaneh Kardanpour, Farnaz Zadehahmadi
      Abstract: A heterogeneous catalyst was synthesized by immobilizing Mo(CO)3 in a UiO-66 metal–organic framework. The benzene ring of the organic linker in UiO-66 was modified via liquid-phase deposition of molybdenum hexacarbonyl, Mo(CO)6, as starting precursor to form the (arene)Mo(CO)3 species inside the framework. The structure of this catalyst was characterized using X-ray diffraction, and chemical integrity was confirmed using Fourier transform infrared and diffuse reflectance UV–visible spectroscopic methods. The metal content was analysed with inductively coupled plasma. Field emission scanning electron microscopy was used to measure particle size and N2 adsorption measurements to characterize the specific surface area. This catalytic system was efficiently applied for epoxidation of alkenes and oxidation of sulfides. The Mo-containing metal–organic framework was reused several times without any appreciable loss of its efficiency.We have developed an eco-friendly solid catalyst by immobilization of Mo complex into the framework of UiO-66 following a post-synthetic modification strategy. The benzene ring of the organic linker in UiO-66 was modified with Mo(CO)3 species. The prepared catalyst was totally characterized and efficiently applied for epoxidation of alkenes and oxidation of sulfides.
      PubDate: 2017-08-22T04:10:44.82014-05:0
      DOI: 10.1002/aoc.3958
       
  • Issue Information
    • Abstract: No abstract is available for this article.
      PubDate: 2017-08-17T06:39:45.573846-05:
      DOI: 10.1002/aoc.3620
       
  • Cover Image
    • Authors: Jamshid Rakhtshah; Sadegh Salehzadeh, Mohammad Ali Zolfigol, Saeed Baghery
      Abstract: The cover image, by Jamshid Rakhtshah et al., is based on the Full Paper Mn(III)–pentadentate Schiff base complex supported on multi-walled carbon nanotubes as a green, mild and heterogeneous catalyst for the synthesis of tetrahydrobenzo[b]pyrans via tandem Knoevenagel–Michael cyclocondensation reaction,
      DOI : 10.1002/aoc.3690.
      PubDate: 2017-08-17T06:39:44.306725-05:
       
  • Polystyrene-supported Pd(II)–N-heterocyclic carbene complex as a
           heterogeneous and recyclable precatalyst for cross-coupling of acyl
           chlorides with arylboronic acids
    • Authors: Barahman Movassagh; Fatemeh Hajizadeh, Elmira Mohammadi
      Abstract: Palladium-catalysed cross-coupling reaction of aroyl chlorides with arylboronic acids was achieved in the presence of polystyrene-supported palladium(II)–N-heterocyclic carbene complex, using K2CO3 in acetone–water, providing diaryl ketones in high yields. Furthermore, the heterogeneous catalyst could be reused up to four times without significant loss of activity.PS-NHC-Pd(II) was used in the Suzuki–Miyaura cross-coupling of aroyl chlorides and arylboronic acids to produce a wide range of diaryl ketones. This heterogeneous catalyst exhibited high efficiency in aqueous media under mild reaction conditions. It was recycled for four successive runs without any significant loss in its activity.
      PubDate: 2017-08-15T03:01:35.205682-05:
      DOI: 10.1002/aoc.3982
       
  • Utilization of industrial waste as a novel adsorbent: Mono/competitive
           adsorption of chromium(VI) and nickel(II) using diatomite waste modified
           by EDTA
    • Authors: Haitao Sha; Yunhai Wu, Yiang Fan
      Abstract: The adsorption of Cr(VI) and Ni(II) using ethylenediaminetetraacetic acid-modified diatomite waste (EDTA-DW) as an adsorbent in single and binary systems was investigated. The EDTA-DW was characterized using various analytical techniques, including Fourier transform infrared spectroscopy, thermogravimetric analysis, Brunauer–Emmett–Teller measurements, X-ray diffraction, scanning electron microscopy and energy-dispersive spectrometry. The adsorption experiment was conducted by varying pH, adsorbent dosage, initial concentration and temperature. In the single system, the sorption data for Cr(VI) fitted the Langmuir isotherm, but the Ni(II) adsorption data fitted well the Freundlich isotherm. The maximum sorption capacity of Cr(VI) and Ni(II) was 2.9 mg g−1 at pH = 3 and 3.64 mg g−1 at pH = 8, respectively. The kinetic data for both Cr(VI) and Ni(II) followed well the pseudo-second-order kinetic model in single and binary systems. Meanwhile, the extended Langmuir and extended Freundlich multicomponent isotherm models were found to fit the competitive adsorption data for Cr(VI) and Ni(II). In addition, in the binary system, the existence of Ni(II) hindered the adsorption of Cr(VI), but the presence of Cr(VI) enhanced the removal of Ni(II). This study provides some realistic and valid data about the usage of modified diatomite waste for the removal of metal ions.The aim was to recycle diatomite waste into a novel adsorbent. To improve adsorption capacity, EDTA was chosen to modify the diatomite waste. The physical and chemical properties of the surface of the adsorbent could be demonstrated by a series of representations. The novel adsorbent shows different adsorption capacities between single system and binary system for Cr(VI) and Ni(II).
      PubDate: 2017-08-15T03:01:31.717777-05:
      DOI: 10.1002/aoc.3977
       
  • Palladium(II) complexes bearing N-alkylpiperidoimidazolin-2-ylidene
           derivatives: Effect of alkyl chain length of ligands on catalytic activity
           
    • Authors: Sinem Çakır; Gülşah Türkmen, Hayati Türkmen
      Abstract: A series of piperidoimidazolinium salts which differ in the chain lengths (butyl, octyl, dodecyl, octadecyl) and their Pd–N-heterocyclic carbene complexes with pyridine were synthesized and characterized using elemental analysis and spectroscopic methods. The effects of these ligands on catalyst activation and the performance of the complexes were studied in Suzuki–Miyaura reactions of arylboronic acid with aryl chlorides. The complex with the ligand having the longest chain length was found to be most active. The results demonstrated that the length of the alkyl chain of the piperidoimidazolin-2-ylidene controlled the dispersion and composition of the nanoparticles and it affected the catalytic activity. The impact of alkyl chain length of piperidoimidazolin-2-ylidene on the Suzuki–Miyaura reactions of arylboronic acid with aryl halides was systematically investigated.Pd-PEPPSI-NHC complexes with various chain lengths were prepared and characterized. The catalytic activities of the complexes in Suzuki–Miyaura C–C coupling reactions were investigated and compared. The aliphatic chain length of the complexes affects the dispersion and composition of the nanoparticles.
      PubDate: 2017-08-15T02:55:48.856972-05:
      DOI: 10.1002/aoc.3969
       
  • Facile synthesis of PtSnZn nanosheet thin film at oil–water interface by
           use of organometallic complexes: An efficient catalyst for methanol
           oxidation and p-nitrophenol reduction reactions
    • Authors: Sajad Saberi Sarmoor; S. Jafar Hoseini, Roghayeh Hashemi Fath, Mahmoud Roushani, Mehrangiz Bahrami
      Abstract: PtSnZn nanosheet thin film with stable and high activity towards methanol electro-oxidation was synthesized via a simple reduction of organometallic precursors including [PtCl2(cod)] (cod = cis,cis-1,5-cyclooctadiene) and [Sn(CH3)4] complexes, in the presence of [Zn(acac)2] (acac = acetylacetonate) complex at toluene–water interface. Catalytic activities of PtSnZn nanosheets were investigated in the p-nitrophenol (p-Nip) reduction and methanol oxidation reactions. The obtained results demonstrate that PtSnZn nanosheets exhibit a good electrocatalytic performance for methanol oxidation reaction, the catalytic activity of the PtSnZn nanosheets being at least 3.5 times higher than that of Pt nanoparticle thin film. Also, the apparent rate constant obtained for p-Nip reduction with the PtSnZn nanosheets is at least 2.3 times higher than that for Pt nanoparticle thin film due to the appropriate interaction between platinum, tin and zinc metals and geometric properties of PtSnZn nanosheet thin film. Nanosheets are highly favourable for superior catalytic performances due to their geometric properties. A facile and efficient route was used to synthesize trimetallic alloy thin film at oil–water interface.A planar toluene–water interface was used as an ideal template for self-assembly of PtSnZn nanosheet thin film. The PtSnZn nanosheets are an efficient catalyst for methanol oxidation and p-nitrophenol reduction reactions.
      PubDate: 2017-08-15T02:55:38.254095-05:
      DOI: 10.1002/aoc.3979
       
  • Synthesis, characterization and photocatalytic application of
           TiO2/magnetic graphene for efficient photodegradation of crystal violet
    • Authors: Zahra Aalimohammadi Piranshahi; Mohammad Behbahani, Fatemeh Zeraatpisheh
      Abstract: A magnetized nano-photocatalyst based on TiO2/magnetic graphene was developed for efficient photodegradation of crystal violet (CV). Scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy and elemental mapping were used to characterize the prepared magnetic nano-photocatalyst. The photocatalytic activity of the synthesized magnetic nano-photocatalyst was evaluated using the decomposition of CV as a model organic pollutant under UV light irradiation. The obtained results showed that TiO2/magnetic graphene exhibited much higher photocatalytic performance than bare TiO2. Incorporation of graphene enhanced the activity of the prepared magnetic nano-photocatalyst. TiO2/magnetic graphene can be easily separated from an aqueous solution by applying an external magnetic field. Effects of pH, magnetized nano-photocatalyst dosage, UV light irradiation time, H2O2 amount and initial concentration of dye on the photodegradation efficiency were evaluated and optimized. Efficient photodegradation (>98%) of the selected dye under optimized conditions using the synthesized nano-photocatalyst under UV light irradiation was achieved in 25 min. The prepared magnetic nano-photocatalyst can be used in a wide pH range (4–10) for degradation of CV. The effects of scavengers, namely methanol (OH• scavenger), p-benzoquinone (O2•− scavenger) and disodium ethylenediaminetetraacetate (hole scavenger), on CV photodegradation were investigated.A synthesized magnetic nano-photocatalyst showed strong synergetic effect between graphene nanosheets and TiO2, which improved charge separation properties. The photocatalytic ability of the synthesized magnetic nano-photocatalyst was evaluated using degradation of crystal violet (CV) as a model organic pollutant under UV light irradiation. The efficiency of degradation of CV in the presence and absence of hydrogen peroxide was >98% after 60 and 25 min, respectively.
      PubDate: 2017-08-15T02:50:55.979628-05:
      DOI: 10.1002/aoc.3985
       
  • Dimethyltin(IV) complexes derived from hydroxamic acid and acylhydrazone
           
    • Authors: Kai Liu; Guoliang Chang, Hui Yan, Zhen Li, Min Hong, Meiju Niu
      Abstract: Two novel dimethyltin(IV) complexes, Me2SnL1(PyCOO)(MeOH) (1) and Me2SnL2 (2) (HL1 = 4-pyridinehydroxamic acid and H2L2 = 2-hydroxy-N′-[(2-hydroxy-5-chlorophenyl)methylidene]benzoylhydrazone), were synthesized and characterized using elemental analyses, Fourier transform infrared and NMR (1H, 13C) spectroscopies and single-crystal X-ray diffraction. In complex 1 the geometry around the tin atom is a six-coordinated distorted octahedral configuration, while complex 2 exhibits five-coordinated distorted trigonal bipyramid geometry. Preliminary in vitro cytotoxicity studies with two human cancer cell lines (HeLa and A549) using MTT assay show that complex 1 is more potent than complex 2. The interactions of the two complexes with calf thymus DNA and bovine serum albumin were also investigated using UV–visible absorption spectral, thermal denaturation and viscosity measurements and docking analysis. Investigations indicate that the structures of the mixed ligands play an important role in the properties of the dimethyltin(IV) complexes, and, to some extent, the antitumor activities of the complexes are partly related to interactions with DNA and some proteins in cancer cells.Two dimethyltin(IV) complexes were synthesized and characterized using some spectroscopy methods and single-crystal X-ray diffraction. In vitro cytotoxicity studies with two human cancer cell lines using MTT assay show that complex 1 is more potent than complex 2 and cisplatin. The results of the interaction of the complexes with CT-DNA and BSA indicated that the mixed ligands play an important role in the properties of the complexes. These studies could be helpful in the development of organotin complexes potential pharmaceutical application.
      PubDate: 2017-08-15T02:45:47.849464-05:
      DOI: 10.1002/aoc.3973
       
  • Metal complexes of chalcone analogue: Synthesis, characterization, DNA
           binding, molecular docking and antimicrobial evaluation
    • Authors: Faten M. Atlam; Marwa N. El-Nahass, Eman A. Bakr, Tarek A. Fayed
      Abstract: A novel chalcone, namely 5-(4-(dimethylamino)phenyl)-1-(thiophen-2-yl)penta-2,4-dien-1-one, DMATP, and its complexes with nickel(II), vanadium(III), palladium(II) and platinum(II) metal ions were synthesized and characterized using a set of chemical and spectroscopic tools including elemental analysis, electrical conductance, magnetic susceptibility and spectral techniques. The interactions of the synthesized chalcone and its metal complexes with DNA were studied using steady-state absorption and emission techniques as well as viscosity and electrochemical measurements. The obtained results confirm DNA intercalation. Additionally, theoretical studies were performed for all the investigated compounds using DFT/B3LYP calculations. The optimized geometries are found to be in good agreement with the suggested experimental structures. The bond lengths, bond angles, chemical reactivity, energy components, binding energy and dipole moment were evaluated. Also, theoretical infrared intensities and thermodynamic parameters for all compounds were calculated. Molecular docking calculations show that the Ni(II) complex exhibits the highest DNA binding activity, which agrees well with the experimental results. Finally, the compounds were screened for antimicrobial activity using several microorganisms.
      PubDate: 2017-08-11T04:42:33.180821-05:
      DOI: 10.1002/aoc.3951
       
  • Synthesis, characterization and application of alumina/ vanadium pentoxide
           nanocomposit by sol–gel method
    • Authors: Hassan Hassani; Batol Zakerinasab, Hoda Hossien Poor
      Abstract: In this work, we report the preparation of Al2O3/V2O5 nanocomposit using vanadium and aluminum nitrate by sol–gel method. Characterization of nanocomposit was carried out by powder X-ray diffractometry (XRD), Fourier transform infrared (FT-IR), scanning electron microscopy (SEM), Energy-Dispersive X-ray (EDX) and UV spectroscopy. Then, applicability of the synthesized nanocomposit was tested as a nanocatalyst for the synthesis of diindolyl oxindole derivatives, an important class of potentially bioactive compounds. The products were obtained in good to high yields from one-pot three-component condensation of isatin with indole. Also, this nanocatalyst has been reused several times, without observable loss of activity.In this work, we report the preparation of Al2O3/V2O5 nanocomposit by sol–gel method. Also, Al2O3/ V2O5 nanocomposit was used for the synthesis of diindolyl oxindole derivatives in good to high yields.
      PubDate: 2017-08-11T04:41:06.059051-05:
      DOI: 10.1002/aoc.3945
       
  • Facile Chemoselective synthesis of
           2-(2-(Methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acids and
           3H,3’H-Spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives
    • Authors: Neda Firoozi; Zohreh Roshan, Mohammad Reza Mohammadizadeh
      Abstract: Oxidation of some derivatives of 4b,9b–dihydroxyindeno[1,2-b]benzofuran-10-one have been investigated in detail using lead(IV) acetate in acetic acid under reflux conditions and periodic acid in aqueous ethanol at room temperature. We realized that during the first 5–15 minutes of the oxidation reactions in lead(IV) acetate/acetic acid system, 3H,3’H-spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives have been synthesized chemo selectively, while, if the reaction mixtures stirred for additional 3 hours, the main products would be 2-(2-(Methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acids. Moreover, room temperature oxidation of 4b,9b–dihydroxyindeno[1,2-b]benzofuran-10-ones by periodic acid (H5IO6), leads to the formation of 3H,3’H-spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives in good to excellent yields.3H,3'H-Spiro[benzofuran-2,1'-isobenzofuran]-3,3'-diones were chemoselectively obtained as the major products during first 15 minutes of the oxidation reactions of 4b,9b-dihydroxyindeno[1,2-b]benzofuran-10-ones with lead(IV) acetate in acetic acid. Interestingly, if the oxidation reactions were continued for 3 hours, 2-(2-(methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acid derivatives would be obtained in moderate to good yields. Additionally, oxidation of dihydroxyindeno[1,2-b]benzofuran-10-ones with periodic acid in aqueous media resulted in the formation of 3H,3'H-spiro[benzofuran-2,1'-isobenzofuran]-3,3'-diones.
      PubDate: 2017-08-11T04:36:42.911124-05:
      DOI: 10.1002/aoc.3963
       
  • Syntheses, silylation, characterization, and antimicrobial and
           antifertility activities of organoboron derivatives of some bioactive
           monofunctional bidentate semicarbazones
    • Authors: Jyoti Bhomia; Jyoti Sharma, Rucha Lakhne, Rachna Sharma, R.S. Gupta, Ram Avatar Sharma, Yashpal Singh
      Abstract: Some new mononuclear organoboron derivatives of the type PhBL1–5(OH) (1a–1e) were synthesized by the reaction of PhB(OH)2 and LH (LH = OC(NH2)NH:NC(CH3)4C6H4R, where R = H (L1H); CH3(L2H); OCH3(L3H); Cl (L4H); Br (L5H)) in 1:1 molar ratio in refluxing tetrahydrofuran (THF). This was followed by the reactions of PhBL1–5(OH) with NH(SiMe3)2 in 2:1 molar ratio in THF to yield new heterodinuclear derivatives of the type PhBL1–5(OSiMe3) (2a–2e). All these newly synthesized complexes were characterized using elemental analyses and their probable structure was proposed on the basis of infrared, 1H NMR, 13C NMR, 11B NMR and 29Si NMR spectral data and mass spectrometry. Semicarbazone ligands and their corresponding mono- and heterodinuclear boron derivatives were screened against pathogenic bacteria (E. coli and P. aeruginosa) and fungi (A. niger and P. peniculosum) to examine their antimicrobial activities. Representative compounds of each series of mono- and heterodinuclear boron derivatives and a ligand were screened for their antifertility activity on male adult Wistar rats.Antimicrobial and antifertility activities of semicarbazones and their corresponding mono- and heterodinuclear boron derivatives have been investigated with a view to examining their potential as drugs.
      PubDate: 2017-08-11T04:36:06.328177-05:
      DOI: 10.1002/aoc.3983
       
  • Ni(II)-Adenine complex coated Fe3O4 nanoparticles as high reusable
           nanocatalyst for the synthesis of polyhydroquinoline derivatives and
           oxidation reactions
    • Authors: Taiebeh Tamoradi; Mohammad Ghadermazi, Arash Ghorbani-Choghamarani
      Abstract: In the present study, Fe3O4 nanoparticles were prepared via simple and versatile procedure. Then, a novel and green catalyst was synthesized by the immobilization of Ni on Fe3O4 nanoparticles coated with adenine. The activity of this nanostructure compound was examined for the oxidation of sulfides, oxidative coupling of thiols and synthesis of polyhydroquinolines. The prepared catalyst was characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma optical emission spectroscopy (ICP-OES), X-ray Diffraction (XRD), thermal gravimetric analysis (TGA), and vibrating sample magnetometer (VSM) measurements. This organometallic catalyst was recovered by the assistance of an external magnetic field from the reaction mixture and reused for seven continuous cycles without noticeable change in its catalytic activity.Ni(II)-Adenine complex coated Fe3O4 nanoparticles has been prepared and characterized with different techniques. This nano structural compound applied as an efficient catalyst for the oxidation of sulfides, oxidative coupling of thiols and synthesis of polyhydroquinolines.
      PubDate: 2017-08-08T05:31:05.285717-05:
      DOI: 10.1002/aoc.3974
       
  • Uniformly dispersed copper nanoparticles onto the modified magnetically
           recoverable nanocatalyst for aqueous synthesis of primary amides
    • Authors: Fariborz Ziaee; Mostafa Gholizadeh, Seyed Mohammad Seyedi
      Abstract: Magnetically recoverable and environmentally friendly Cu-based heterogeneous catalyst has been synthesized for the one-pot conversion of aldehydes to their corresponding primary amides. The Fe3O4@SiO2 nanocomposites were prepared by synthesis of Fe3O4 magnetic nanoparticles (MNPs) which was then coated with a silica shell via Stöber method. Bi-functional cysteine amino acid was covalently bonded onto the siliceous shell of nanocatalyst. The CuII ions were then loaded onto the modified surface of nanocatalyst. Finally, uniformly dispersed copper nanoparticles were achieved by reduction of CuII ions with NaBH4. Amidation reaction of aryl halides with electron-withdrawing or electron-donating groups and hydroxylamine hydrochloride catalyzed with Fe3O4@SiO2@Cysteine-copper (FSC-Cu) MNPs in aqueous condition gave an excellent yield of products. The FSC-Cu MNPs could be easily isolated from the reaction mixture with an external magnet and reused at least 8 times without significant loss in activity.Magnetically recoverable and environmentally friendly Cu-based heterogeneous catalyst has been synthesized for the one-pot conversion of aldehydes to their corresponding primary amides. Cysteine was used as a ligand for modification of silica coated magnetic nanoparticles which used for generation of Cu NPs. The mild reaction conditions, broad substrate scope make FSC-Cu MNPs efficient and environmentally friendly for the synthesis of primary amides.
      PubDate: 2017-08-01T23:12:24.996548-05:
      DOI: 10.1002/aoc.3925
       
  • Reaction of dimethylplatinum(II) complexes with PhCH2CH2Br: Comparative
           reactivity with CH3CH2Br and PhCH2Br and synthesis of Pt(IV) complexes
    • Authors: Mozhgan Samandar Sangari; Mehdi Rashidi, S. Masoud Nabavizadeh, Banafshe Askari, Fatemeh Niroomand Hosseini
      Abstract: Oxidative addition of 2-phenylethylbromide (PhCH2CH2Br) to dimethylplatinum(II) complexes [PtMe2(NN)] (1a, NN = 2,2′-bipyridine (bpy); 1b, NN = 1,10-phenanthroline (phen)) afforded the new organoplatinum(IV) complexes [PtMe2(Br)(PhCH2CH2)(bpy)], as a mixture of trans (2a) and cis (3a) isomers, and [PtMe2(Br)(PhCH2CH2)(phen)], as a mixture of trans (2b) and cis (3b) isomers, respectively. The new Pt(IV) complexes were readily characterized using multinuclear (1H and 13C) NMR spectroscopy and elemental microanalysis. The crystal structure of 2a was further determined using X-ray crystallography indicating an octahedral geometry around the platinum centre. A comparison of reactivity of RCH2Br reagents (R = CH3, Ph or PhCH2) in their oxidative addition reactions with complex 1a, with an emphasis on the effects of the R groups of alkyl halides, was also conducted using density functional theory.Oxidative addition of 2-phenylethylbromide to dimethylplatinum(II) complexes afforded new organoplatinum(IV) complexes as a mixture of trans and cis addition products.
      PubDate: 2017-07-28T06:28:56.77112-05:0
      DOI: 10.1002/aoc.3954
       
  • A ferrocene-containing porous organic polymer linked by tetrahedral
           silicon-centered units for gas sorption
    • Authors: Qingyu Ma; Yipeng Qi, Jianquan Li, Weiguo Wang, Xuejiao Sun
      Abstract: A novel ferrocene-containing porous organic polymer (FPOP) has been prepared by Sonogashira-Hagihara coupling reaction of 1,1′-dibromoferrocene and tetrakis(4-ethynylphenyl)silane. Compared with other polymers, the resulting polymer possesses excellent thermal stability with the decomposition temperature of 415°C and high porosity with Brunauer–Emmett–Teller (BET) surface area of 542 m2 g−1 as measured by nitrogen adsorption-desoprtion isotherm at 77 K. For applications, it shows moderate carbon dioxide uptakes of up to 1.42 mmol g−1 (6.26 wt%) at 273 K/1.0 bar and 0.82 mmol g−1 (3.62 wt%) at 298 K/1.0 bar, and hydrogen capacity of up to 0.45 mmol g−1 (0.91 wt%) at 77 K/1.0 bar, indicating that FPOP might be utilized as a promising candidate for storing carbon dioxide and hydrogen. Although FPOP possesses lower porosity than many porous polymers, the gas capacities are higher or comparable to them, thereby revealing that the incorporation of ferrocene units into the network is an effective strategy to enhance the affinity between the framework and gas.A novel ferrocene-containing porous organic polymer (FPOP) constructed from 1,1′-dibromoferrocene and tetrakis(4-ethynylphenyl)silane exhibits excellent thermal stability, high porosity and can be utilized as a promising candidate for storing CO2 and H2.
      PubDate: 2017-07-27T01:56:27.836705-05:
      DOI: 10.1002/aoc.3935
       
  • Synthesis and characterization of bromine source immobilized on
           diethylenetriamine-functionalized magnetic nanoparticles: A novel,
           versatile and highly efficient reusable catalyst for organic synthesis
    • Authors: Lotfi Shiri; Sadegh Rahmati, Zahra Ramezani Nejad, Mosstafa Kazemi
      Abstract: Bromine source immobilized on magnetic nanoparticles functionalized with diethylenetriamine was successfully synthesized and characterized using Fourier transform infrared spectroscopy, scanning electron microscopy, vibrating sample magnetometry, thermogravimetric analysis and X-ray diffraction. The catalytic activity in the synthesis of 2,3-dihydroquinazoline-4(1H)-one and polyhydroquinoline derivatives and in Knoevenagel condensation was studied. The bromine catalyst can be magnetically recovered and reused several times without significant loss of its catalytic activity. All products were obtained in high to excellent yields.Bromine source immobilized on magnetic nanoparticles functionalized with diethylenetriamine is shown to be a versatile and highly efficient reusable catalyst for Knoevenagel condensation and the synthesis of 2,3-dihydroquinazoline-4(1H)-one and polyhydroquinoline derivatives.
      PubDate: 2017-01-31T01:35:50.852809-05:
      DOI: 10.1002/aoc.3687
       
  • Palladium nanoparticles immobilized on magnetic methionine-functionalized
           chitosan: A versatile catalyst for Suzuki and copper-free Sonogashira
           reactions of aryl halides at room temperature in water as only solvent
    • Authors: Abdol R. Hajipour; Zeinab Tavangar-Rizi
      Abstract: The preparation of an efficient heterogeneous catalyst system based on the immobilization of palladium nanoparticles on a magnetic nanoparticle core (ImmPd(0)-MNPs) is described. The new catalytic system was characterized using transmission and scanning electron microscopies, X-ray diffraction, energy-dispersive X-ray and Fourier transform infrared spectroscopies, thermogravimetric analysis, vibrating sample magnetometry and inductively coupled plasma analysis. We have demonstrated that ImmPd(0)-MNPs is an efficient and reusable catalyst for the Suzuki–Miyaura and Sonogashira coupling reactions of various types of aryl halides in water as a green and environmentally acceptable solvent. Moreover, the reactions were carried out efficiently at room temperature. The catalyst was easily separated using an external magnet from the reaction mixture and recycled ten times without significant loss of activity.The preparation and characterization of a new and highly efficient magnetic palladium catalyst and its applications in Suzuki reaction of aryl halides in water at room temperature are reported.
      PubDate: 2017-01-29T23:55:42.939411-05:
      DOI: 10.1002/aoc.3701
       
  • Effect of solvent coordination on the structure of β-diketone-based
           vanadyl complexes and assessment of in vitro antidiabetic activity and
           cytotoxicity
    • Authors: Chinna Pullaih Chinthala; Sheela Angappan
      Abstract: The physicochemical properties, thereby the biological efficacy, of metal complexes are affected based on their structure and geometry that vary in the presence of coordinating and non-coordinating solvents. To investigate this, in the present work, we synthesized three hitherto unreported β-diketone-based oxovanadium(IV) complexes, namely [VO(tfdmh)2] (tfdmh =1,1,1-trifluro-5,5-dimethyl-2,4-hexanedione), [VO(dmh)2] (dmh = 2,2-dimethyl-3,5-hexanedione) and [VO(dbm)2] (dbm = 1,3-diphenylpropane-1,3-dione), and characterized them using electron paramagnetic resonance, UV–visible, Fourier transform infrared and electrospray ionization mass spectroscopies and single-crystal X-ray diffraction. The structural changes in the presence of dichloromethane, dimethylsulfoxide and dimethylformamide were analysed using spectroscopic techniques. Further, in vitro glucose uptake efficacy and cytotoxicity were assessed using C2C12 (rat skeletal muscle) and HeLa (human cervical cancer) cell lines, respectively.The change in geometry of synthesized oxovanadium (IV) complexes by solvent coordination has been confirmed by X-ray analyses. The antidiabetic activity and cytoxicity of the complexes were assessed by in vitro studies using C2C12 (rat skeletal muscle) and He La cell lines respectively. The synthesized complexes lower the glucose in cancer cells by their glucose uptake ability thereby interfering in metabolic activity preventing cell growth and multiplication.
      PubDate: 2017-01-29T21:55:43.203489-05:
      DOI: 10.1002/aoc.3700
       
  • Palladium nanoparticles immobilized on amphiphilic and hyperbranched
           polymer-functionalized magnetic nanoparticles: An efficient
           semi-heterogeneous catalyst for Heck reaction
    • Authors: Seyed Jamal Tabatabaei Rezaei; Azin Shamseddin, Ali Ramazani, Asemeh Mashhadi Malekzadeh, Pegah Azimzadeh Asiabi
      Abstract: To address the obstacles facing the use of palladium-based homogeneous and heterogeneous catalysts in C─C cross-coupling reactions, a novel semi-heterogeneous support was developed based on hyperbranched poly(ethylene glycol)-block-poly(citric acid)-functionalized Fe3O4 magnetic nanoparticles (Fe3O4@PCA-b-PEG). Because of the surface modification of the Fe3O4 nanoparticles with amphiphilic and hyperbranched polymers (PCA-b-PEG), these hybrid materials are not only soluble in a wide range of solvents (e.g. water, ethanol and dimethylformamide) but also are able to trap Pd2+ ions via complex formation of free carboxyl groups of the PCA dendrimer with metal ions. The reduction of trapped palladium ions in the dendritic shell of Fe3O4@PCA-b-PEG leads to immobilized palladium nanoparticles. The morphology and structural features of the catalyst were characterized using various microscopic and spectroscopic techniques. The catalyst was effectively used in the palladium-catalysed Mizoroki–Heck coupling reaction in water as a green solvent. In addition, the catalyst can be easily recovered from the reaction mixture by applying an external magnetic field and reused for more than ten consecutive cycles without much loss in activity, exhibiting an example of a sustainable and green methodology.A novel magnetically retrievable palladium-based semi-heterogeneous catalytic system (Fe3O4@PCA/Pd(0)-b-PEG) has been developed for the C─C cross-coupling reactions of aryl halides with olefinic compounds in an environmentally friendly solvent under ligand-free ambient conditions.
      PubDate: 2017-01-29T21:45:43.284003-05:
      DOI: 10.1002/aoc.3707
       
  • A facile and efficient synthesis of 3-cyanoindoles by a simple
           palladium(II)-catalyzed C─H activation of indoles
    • Authors: Hailiang Chu; Mengping Guo, Yanping Yi, Yongju Wen, Lanjiang Zhou, Hongwei Huang
      Abstract: An efficient trans-PdCl2(NH2CH2COOH)2-catalyzed direct C3-cyanation of indole C─H bonds is described. Notably, free (N─H)-indoles reacted smoothly using the procedure, and the desired product 3-cyanoindoles were obtained in good to excellent yields.An efficient trans-PdCl2(NH2CH2COOH)2-catalyzed direct C3-cyanation of indole C─H bond is described. Notably, free (N─H)-indoles reacted smoothly using the procedure, and the desired product 3-cyanoindoles were obtained in good to excellent yields.
      PubDate: 2017-01-24T01:41:35.700922-05:
      DOI: 10.1002/aoc.3706
       
  • Synthesis and characterization of water-soluble copper(II), cobalt(II) and
           zinc(II) complexes derived from 8-hydroxyquinoline-5-sulphonic acid: DNA
           binding and cleavage studies
    • Authors: Ammavasi Gubendran; Mookkandi Palsamy Kesavan, Srinivasan Ayyanaar, Jeyaraj Dhaveethu Raja, Periyakaruppan Athappan, Jegathalaprathaban Rajesh
      Abstract: Three water-soluble complexes, [Cu2L2Cl2] (1), [CoL2(im)2] (2) and [ZnLClH2O] (3) (HL = 8-hydroxyquinoline-5-sulphonic acid; im = N-methylimidazole), were prepared and characterized using various spectral techniques. The DNA binding behaviour of complexes 1–3 was studied using UV–visible and circular dichroism (CD) spectra and cyclic voltammetry. All three complexes exhibit hypochromism but complexes 1 and 3 alone give a red shift of 4 nm with a significant binding constant of Kb = 2.1 × 104 and 1.0 × 104 M−1, respectively, but complex 2 shows no red shift with lower Kb of 4.1 × 103 M−1. The voltammetric E1/2 of complex 1 on interaction with herring sperm DNA shifts to a more positive potential, as expected, than complex 2 due to higher DNA affinity. Additionally, analysis of electrochemical data yields a value of K+/K2+ greater than one suggesting that complex 1 binds to DNA through intercalation in the M(I) state. Evidently in CD spectral analysis, complex 1 exhibits a decrease in molar ellipticity with a red shift of 10 nm and a significant decrease in intensity compared to complexes 2 and 3. This clearly indicates that complex 1 induces the B  A transition to a greater extent than 2 and 3. Oxidative cleavage using circular plasmid pUC18 DNA with complex 1 was investigated using gel electrophoresis. Interestingly, complex 1 displays a strong DNA binding affinity and is efficient in cleaving DNA in the presence of H2O2 at pH = 8.0 at 37 °C.Three water-soluble complexes of Cu(II), Co(II) and Zn(II) containing 8-hydroxyquinoline-5-sulfonic acid ligand were prepared and characterized. From the results of spectroscopic and electrochemical methods, all three complexes have significant interactions with DNA. Oxidative cleavage studies using circular plasmid pUC18 DNA with the Cu(II) complex were conducted using gel electrophoresis.
      PubDate: 2017-01-24T01:41:14.662191-05:
      DOI: 10.1002/aoc.3708
       
  • SBA-15-supported N-coordinate ruthenium(II) materials bearing
           sulfonamide-type ligands: Effect of ligand backbones on catalytic transfer
           hydrogenation of ketones and aldehydes
    • Authors: Serkan Dayan; Nilgun Kayaci, Nilgun Kalaycioglu Ozpozan, Osman Dayan
      Abstract: [RuLCl(p-cymene)] (L = N-arylsulfonylphenylenediamine) complexes (2a–d) were synthesized from the reaction between [Ru(p-cymene)Cl2]2 and ligand. Additionally, SBA-15–[RuLCl(p-cymene)] derived catalysts (3a–d) were successfully immobilized onto mesoporous silica (SBA-15) by an easily accessible approach. The structural elucidations of 2a–d and 3a–d were carried out with various methods such as 1H NMR, 13C NMR and infrared spectroscopies, elemental analysis, thermogravimetric/differential thermal analysis, nitrogen adsorption–desorption and scanning electron microscopy/energy-dispersive X-ray analysis. The Ru(II) complexes and materials were found to be highly active and selective catalysts for the transfer hydrogenation (TH) reaction of aldehydes and ketones. The influence of various 1,2-phenylenediamines on the reactivity of the catalysts (complexes or materials) was studied and the catalysts (2d and 3d) with a 4,5-dichlorophenylenediamine substituent showed the best activity (the maximum turnover frequencies are 2916 and 2154 h−1 for TH of 4-fluoroacetophenone, and 6000 and 4956 h−1 for TH of 4-chlorobenzaldehyde).Ruthenium(II) complexes and supported complexes were prepared from N-arylsulfonylphenylenediamines. They were used as catalysts in transfer hydrogenation of acetophenone derivatives and aromatic aldehydes.
      PubDate: 2017-01-20T03:30:43.481273-05:
      DOI: 10.1002/aoc.3699
       
  • Anchoring of Cu(II)–vanillin Schiff base complex on MCM-41: A highly
           efficient and recyclable catalyst for synthesis of sulfides and
           5-substituted 1H–tetrazoles and oxidation of sulfides to sulfoxides
    • Authors: Maryam Khanmoradi; Mohsen Nikoorazm, Arash Ghorbani-Choghamarani
      Abstract: A copper(II)–vanillin complex was immobilized onto MCM-41 nanostructure and was used as an inexpensive, non-toxic and heterogeneous catalyst in the synthesis of symmetric aryl sulfides by the cross-coupling of aromatic halides with S8 as an effective sulfur source, in the oxidation of sulfides to sulfoxides using 30% H2O2 as a green oxidant and in the synthesis of 5-substituted 1H–tetrazoles from a smooth (3 + 2) cycloaddition of organic nitriles with sodium azide (NaN3). The products were obtained in good to excellent yields. This catalyst could be reused several times without loss of activity. Characterization of the catalyst was performed using Fourier transform infrared, energy-dispersive X-ray and atomic absorption spectroscopies, X-ray diffraction, thermogravimetric analysis, and scanning and transmission electron microscopies.The cupper (II)-vanillin complex immobilized onto MCM-41 as heterogeneous catalyst was used for the synthesis of symmetrical aryl sulfides, oxidation of sulfides to sulfoxides and synthesis of 5-substituted 1H-tetrazoles with good to excellent yields. Characterization of catalyst was performed by FT-IR, XRD, TGA, SEM, TEM, EDX and AAS techniques.
      PubDate: 2017-01-20T00:11:06.415737-05:
      DOI: 10.1002/aoc.3693
       
  • Synthesis, characterization and catalytic properties of
           tetrachlorocuprate(II) immobilized on layered double hydroxide
    • Authors: Mojtaba Amini; Mohammad Nikkhoo, S. Morteza F. Farnia
      Abstract: Readily prepared copper(II) immobilized on layered double hydroxide has been found to effectively catalyse the 1,3-dipolar cycloaddition (CuAAC) of a variety terminal alkynes and benzyl azides generated in situ from sodium azide and benzyl halides furnishing the corresponding 1,2,3-triazoles in excellent yields. The advantages of the protocol are short reaction time, mild reaction conditions, reusability of the catalyst and applicability to a wide range of substrates.The 1,3-dipolar cycloaddition of a variety terminal alkynes and organic azides in the presence of CuII−immobilized layered double hydroxide was studied.
      PubDate: 2017-01-16T21:20:28.525483-05:
      DOI: 10.1002/aoc.3710
       
  • Oxidation of alkanes and secondary alcohols to ketones with tert-butyl
           hydroperoxide catalyzed by a water-soluble ruthenium complex under
           solvent-free conditions
    • Authors: Yuecheng Zhang; Liyuan Zhao, Hongyu Zhang, Rong Huang, Jiquan Zhao
      Abstract: An easily synthesized water-soluble ruthenium complex, [C6H5CH2N(CH3)2H]2[Ru(dipic)Cl3] (dipic =2,6-pyridinedicarboxylate), as a catalyst showed high efficiency in the oxidation of alkanes and secondary alcohols to their corresponding ketones under solvent-free and low-catalyst-loading conditions. This catalytic system could tolerate a variety of substrates and gave the corresponding ketones in good to excellent yields. The products were easily separated and purified due to the water solubility of the ruthenium complex.A water soluble ruthenium complex, [C6H5CH2N(CH3)2H]2[Ru(dipic)Cl3], was prepared, which showed good catalytic performance in the oxidation of various alkanes and secondary alcohols with aqueous TBHP as oxidant under solvent-free conditions. The products were easily separated and purified due to the water solubility of the ruthenium complex.
      PubDate: 2017-01-16T21:15:29.374386-05:
      DOI: 10.1002/aoc.3709
       
  • Tin(IV) Schiff base complexes derived from pyridoxal: Synthesis,
           spectroscopic properties and cytotoxicity
    • Authors: José M. Galván-Hidalgo; Guillermo M. Chans, Teresa Ramírez-Apan, Antonio Nieto-Camacho, Simón Hernández-Ortega, Elizabeth Gómez
      Abstract: The synthesis of monomeric pentacoordinated diorganotin(IV) complexes derived from pyridoxal hydrochloride and 4- or 5-R-substituted ortho-aminophenols is described. The complexes were characterized using UV–visible, infrared, mass, 1H NMR, 13C NMR and 119Sn NMR spectral techniques. The molecular structure of three complexes was established using X-ray diffraction: 3b and 3d show a distorted trigonal bipyramidal geometry, in which the basal plane is defined by the butyl groups and the iminic nitrogen atom, whereas the oxygen atoms from the aromatic ring occupy axial positions; in contrast, complex 3e exhibits a square pyramidal geometry. The cytotoxic activity of all complexes against human cell lines U-251 (glioblastoma), K-562 (chronic myelogenous leukemia), HCT-15 (human colorectal cancer), MCF-7 (human breast cancer) and SKLU-1 (non-small-cell lung cancer) was evaluated, and the inhibitory percentage values indicated higher activity than the reference standard, cisplatin. Acute toxicity studies were performed in vivo for the prepared complexes to determine the lethal medium dose (LD50) after intraperitoneal administration to mice.A series of monomeric pentacoordinated diorganotin(IV) complexes derived from pyridoxamine dihydrochloride were synthesized using a multicomponent reaction. The preliminary structure–activity relationship is discussed. Their cytotoxic activity and acute toxicity after intraperitoneal administration to mice were evaluated.
      PubDate: 2017-01-16T21:10:24.767087-05:
      DOI: 10.1002/aoc.3704
       
  • Synthesis and investigation of dual pH- and temperature-responsive
           behaviour of poly[2-(dimethylamino)ethyl methacrylate]-grafted gold
           nanoparticles
    • Authors: Maryam Mohammadi; Mehdi Salami-Kalajahi, Hossein Roghani-Mamaqani, Marzieh Golshan
      Abstract: Gold nanoparticles (AuNPs) were synthesized by reduction of chloroauric acid (HAuCl4) aqueous solution with hydrazine monohydrate. The AuNPs were immediately treated with cysteamine to obtain amine-functionalized nanoparticles (Au-NH2). The reaction of Au-NH2 with epichlorohydrin and subsequent treatment with sodium hydroxide gave epoxidized AuNPs (Au-EP). Then, thiol-capped AuNPs (Au-SH) were synthesized by reaction of Au-EP with cysteamine. A ‘grafting to’ approach was utilized to graft bromine-terminated poly(N,N′-dimethylaminoethyl methacrylate), synthesized via aqueous atom transfer radical polymerization, with various molecular weights (6280, 25 800, 64 200 and 87 600 g mol−1) onto Au-SH to obtain Au-P1, Au-P2, Au-P3 and Au-P4 samples, respectively. All samples were exposed to temperature and pH variations, and Z-average diameter was monitored using dynamic light scattering. According to the results, polymer-grafted nanoparticles collapsed at lower temperatures with increasing solution pH for all molecular weight ranges due to deprotonation of tertiary amine groups. However, higher molecular weight polymers were more sensitive to pH variation especially in alkaline media. Also, a high degree of agglomeration was observed for Au-P4 nanoparticles in alkaline media on increasing the temperature to 55 and 65 °C.The effect of the molecular weight of poly[2-(dimethylamino)ethyl methacrylate] chains attached to hybrid gold nanoparticles on the responsive behaviour has been investigated.
      PubDate: 2017-01-16T21:05:28.075387-05:
      DOI: 10.1002/aoc.3702
       
  • Copper oxide supported on magnetic nanoparticles (CuO@γ-Fe2O3): An
           efficient and magnetically separable nanocatalyst for addition of amines
           to carbodiimides towards synthesis of substituted guanidines
    • Authors: Sepideh Abbasi; Dariush Saberi, Akbar Heydari
      Abstract: Copper oxide supported on magnetic nanoparticles was used as a green magnetic nanocatalyst for hydroamination of carbodiimides towards the synthesis of guanidines. Easy preparation and separation, low cost, non-sensitivity to moisture and reusability of the catalyst along with diversity and high yield of products are significant features of this method.Copper oxide supported on magnetic nanoparticles was employed as an efficient and magnetically separable catalyst for hydroamination of carbodiimides towards the synthesis of guanidines.
      PubDate: 2017-01-16T20:55:23.382311-05:
      DOI: 10.1002/aoc.3695
       
  • Synthesis of novel macrocyclic Schiff's-base and its complexes having N2O2
           group of donor atoms. Characterization and anticancer screening are
           studied
    • Authors: Ehab M. Zayed; Mohamed A. Zayed, Asmaa M. Fahim, Fatma A. El-Samahy
      Abstract: Novel Schiff base [N′,N′″-(((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))di(benzohydrazide)] was formed by the condensation reaction of benzohydrazide with 2,2′-(ethane-1,2-diylbis(oxy))dibenzaldehyde. Its reaction with various metal ions was studied and the structures of the new products were characterized using common analytical and spectroscopic methods. All the metal complexes have pronounced anticancer activities. The antimicrobial activities against Gram-negative and Gram-positive bacteria were investigated.A novel Schiff base and its conformational changes on complexation with various transition metal ions have been studied. The antimicrobial activity of the compounds was studied against Gram-negative and Gram-positive bacteria. Anticancer screening studies were performed using human colorectal cancer (HCT), hepatic cancer (HepG2) and breast cancer (MCF-7) cell lines.
      PubDate: 2017-01-16T20:50:27.367142-05:
      DOI: 10.1002/aoc.3694
       
  • Palladium-catalyzed reductive homocoupling of aryl sulfonates via cleavage
           of C─O bond at room temperature
    • Authors: Shuangling Zhong; Mengxin Chen, Ge Liu, Chenggang Sun, Wencong Liu
      Abstract: Palladium-catalyzed reductive homocoupling of aryl sulfonates has been successfully achieved under mild conditions. This transformation is a new method for the homocoupling reaction of aryl sulfonates at room temperature via the cleavage of C─O bonds, thus providing an alternative synthesis of symmetric biaryls. The reported reductive homocoupling reaction is tolerant of many common functional groups regardless of electron-donating or electron-withdrawing nature, making this newly developed transformation important for complementing Ullmann coupling.Experimental Section.Typical procedure for the products.Pd-catalyzed reductive homocoupling of aryl sulfonates has been successfully achieved under mild conditions. This is a new method for the homocoupling reaction of aryl sulfonates via the cleavage of C─O bonds, thus providing an alternative synthesis of symmetric biaryls. The reductive homocoupling reactions are tolerant to many common functional groups, making this newly developed transformation important for complementing Ullmann coupling.
      PubDate: 2017-01-12T00:00:53.262677-05:
      DOI: 10.1002/aoc.3705
       
  • Mn(III)–pentadentate Schiff base complex supported on multi-walled
           carbon nanotubes as a green, mild and heterogeneous catalyst for the
           synthesis of tetrahydrobenzo[b]pyrans via tandem Knoevenagel–Michael
           cyclocondensation reaction
    • Authors: Jamshid Rakhtshah; Sadegh Salehzadeh, Mohammad Ali Zolfigol, Saeed Baghery
      Abstract: Mn(III)–pentadentate Schiff base complex supported on multi-walled carbon nanotubes as a recyclable and reusable, green and nano-heterogeneous catalyst was designed and fully characterized using infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, inductively coupled plasma mass spectrometry, elemental analysis and thermogravimetric analysis. A facile, eco-friendly, mild and green procedure was developed for the one-pot three-component synthesis of tetrahydrobenzo[b]pyrans via tandem Knoevenagel–Michael cyclocondensation reactions between aromatic aldehydes, 1,3-diones and malononitrile using a catalytic amount of Mn(III)–pentadentate Schiff base complex supported on MWCNTs as an efficient recyclable heterogeneous catalyst under solvent-free conditions at room temperature. This process has the advantages of easy availability, stability, recyclability and eco-friendliness of the catalyst, short reaction times, high to excellent yields and simple work-up procedure.The synthesis of Mn(III)–pentadentate Schiff base complex supported on multi-walled carbon nanotubes (MWCNTs) and its efficient and green application as a recyclable heterogeneous catalyst for tandem Knoevenagel–Michael cyclocondensation reactions between malononitrile, aromatic aldehydes and 1,3-diones are reported.
      PubDate: 2017-01-11T22:35:41.456123-05:
      DOI: 10.1002/aoc.3690
       
  • Metallated porphyrin noncovalent interaction with reduced graphene
           oxide-modified electrode for amperometric detection of environmental
           pollutant hydrazine
    • Authors: Subramanian Sakthinathan; Subbiramaniyan Kubendhiran, Shen-Ming Chen, Mani Govindasamy, Fahad M.A. Al-Hemaid, M. Ajmal Ali, P. Tamizhdurai, S. Sivasanker
      Abstract: A reduced graphene oxide/platinum(II) tetraphenylporphyrin nanocomposite (RGO/Pt-TPP)-modified glassy carbon electrode was developed for the selective detection of hydrazine. The RGO/Pt-TPP nanocomposite was successfully prepared via noncovalent π–π stacking interaction. The prepared nanocomposite was characterized using nuclear magnetic resonance, electrochemical impedance, ultraviolet–visible and Raman spectroscopies, scanning electron microscopy and X-ray diffraction. The electrochemical detection of hydrazine was performed via cyclic voltammetry and amperometry. The RGO/Pt-TPP nanocomposite exhibited good electrocatalytic activity towards detection of hydrazine with low overpotential and high oxidation peak current. The fabricated sensor exhibited a wide linear range from 13 nM to 232 μM and a detection limit of 5 nM. In addition, the fabricated sensor selectively detected hydrazine even in the presence of 500-fold excess of common interfering ions. The fabricated electrode exhibited good sensitivity, stability, repeatability and reproducibility. In addition, the practical applicability of the sensor was evaluated in various water samples with acceptable recoveries.The reduced graphene oxide / platinum (II) tetraphenyl porphyrin nanocomposite (RGO/Pt-TPP) modified GCE was developed for the selective detection of hydrazine. The prepared nanocomposite was characterized by suitable physical and chemical characterization. The RGO/Pt-TPP nanocomposite exhibited a wide linear range from 13 nM to 232 µM and the detection limit (LOD) of 5 nM towards detection of hydrazine. In addition, the practical applicability of the sensor evaluated in different water samples with acceptable recoveries.
      PubDate: 2017-01-04T21:07:17.881821-05:
      DOI: 10.1002/aoc.3703
       
  • Copper nanoparticles supported on polyaniline-functionalized multiwall
           carbon nanotubes: An efficient and recyclable catalyst for synthesis of
           unsymmetric sulfides using potassium ethyl xanthogenate in water
    • Authors: Abdol R. Hajipour; Saeideh Jajarmi, Zahra Khorsandi
      Abstract: A new and powerful polyaniline-functionalized carbon nanotube-supported copper(II) nanoparticle catalyst was successfully prepared and evaluated as a heterogeneous catalyst for the one-pot synthesis of unsymmetric thioethers by coupling of aryl, alkyl and benzyl halides using potassium ethyl xanthogenate as source of sulfur in water. All of these reactions gave the desired products in good to excellent yields. The catalyst is available, air-stable and can be reused several times without significant loss in its catalytic activity.Polyaniline functionalized multiwall carbon nanotubes supported copper(II) nanoparticles were prepared, characterized and used as catalyst in the synthesis of unsymmetrical sulfides using potassium ethyl xanthogenate as source of sulfur in water. The whole of these reactions gave the desired products in excellent yields. The catalyst is available and air-stable.
      PubDate: 2017-01-04T20:55:31.255755-05:
      DOI: 10.1002/aoc.3697
       
  • Pd and Ni complexes of a novel vinylidene β-diketimine ligand: Their
           application as catalysts in Heck coupling and alkyne trimerization
    • Authors: Raghavendra Beesam; Dastagiri Reddy Nareddula
      Abstract: A β-diketimine ligand with vinylidene substitution at γ-carbon, CH2C(CH3CNAr)2 (Ar = 2,6-diisopropylphenyl) (L2), was synthesized by treating β-diketimine H2C(CH3CNAr)2 with n-BuLi followed by paraformaldehyde. L2 formed the homobimetallic ether-bridged β-diketiminate complex [O{(CH2-β-diketiminate)Pd(OAc)}2] (1) with (PdOAc)2. It also gave complexes [L2PdCl2] (2) and [L2NiBr2] (3) when treated with PdCl2(CH3CN)2 and NiBr2(dimethoxyethane), respectively. All the compounds were characterized using 1H/13C NMR spectroscopy and single-crystal X-ray diffraction studies. The catalytic activity of Pd and Ni complexes 1, 2 and 3 was explored in Heck coupling and alkyne trimerization reactions and it was found that they are very good catalysts. The results are reported in detail.Pd and Ni complexes of a novel vinylidene β-diketimine were synthesized and their catalytic activity in Mizoroki–Heck coupling and alkyne trimerization reactions was explored.
      PubDate: 2017-01-04T20:45:55.25838-05:0
      DOI: 10.1002/aoc.3696
       
 
 
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