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  Subjects -> CHEMISTRY (Total: 852 journals)
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    - CHEMISTRY (598 journals)
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CHEMISTRY (598 journals)                  1 2 3 | Last

Showing 1 - 200 of 735 Journals sorted alphabetically
2D Materials     Hybrid Journal   (Followers: 10)
Accreditation and Quality Assurance: Journal for Quality, Comparability and Reliability in Chemical Measurement     Hybrid Journal   (Followers: 26)
ACS Catalysis     Full-text available via subscription   (Followers: 38)
ACS Chemical Neuroscience     Full-text available via subscription   (Followers: 18)
ACS Combinatorial Science     Full-text available via subscription   (Followers: 23)
ACS Macro Letters     Full-text available via subscription   (Followers: 24)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
ACS Nano     Full-text available via subscription   (Followers: 252)
ACS Photonics     Full-text available via subscription   (Followers: 12)
ACS Synthetic Biology     Full-text available via subscription   (Followers: 23)
Acta Chemica Iasi     Open Access   (Followers: 2)
Acta Chimica Sinica     Full-text available via subscription   (Followers: 1)
Acta Chimica Slovaca     Open Access   (Followers: 1)
Acta Chimica Slovenica     Open Access  
Acta Chromatographica     Full-text available via subscription   (Followers: 9)
Acta Facultatis Medicae Naissensis     Open Access  
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5)
Acta Scientifica Naturalis     Open Access   (Followers: 2)
adhäsion KLEBEN & DICHTEN     Hybrid Journal   (Followers: 5)
Adhesion Adhesives & Sealants     Hybrid Journal   (Followers: 8)
Adsorption Science & Technology     Full-text available via subscription   (Followers: 5)
Advanced Functional Materials     Hybrid Journal   (Followers: 51)
Advanced Science Focus     Free   (Followers: 3)
Advances in Chemical Engineering and Science     Open Access   (Followers: 57)
Advances in Chemical Science     Open Access   (Followers: 13)
Advances in Chemistry     Open Access   (Followers: 15)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Enzyme Research     Open Access   (Followers: 9)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 16)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 9)
Advances in Materials Physics and Chemistry     Open Access   (Followers: 21)
Advances in Nanoparticles     Open Access   (Followers: 15)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15)
Advances in Polymer Science     Hybrid Journal   (Followers: 41)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Science and Technology     Full-text available via subscription   (Followers: 12)
African Journal of Bacteriology Research     Open Access  
African Journal of Chemical Education     Open Access   (Followers: 2)
African Journal of Pure and Applied Chemistry     Open Access   (Followers: 7)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Al-Kimia : Jurnal Penelitian Sains Kimia     Open Access  
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Journal of Biochemistry and Biotechnology     Open Access   (Followers: 66)
American Journal of Biochemistry and Molecular Biology     Open Access   (Followers: 15)
American Journal of Chemistry     Open Access   (Followers: 27)
American Journal of Plant Physiology     Open Access   (Followers: 14)
American Mineralogist     Hybrid Journal   (Followers: 14)
Analyst     Full-text available via subscription   (Followers: 39)
Angewandte Chemie     Hybrid Journal   (Followers: 179)
Angewandte Chemie International Edition     Hybrid Journal   (Followers: 229)
Annales UMCS, Chemia     Open Access   (Followers: 1)
Annals of Clinical Chemistry and Laboratory Medicine     Open Access   (Followers: 4)
Annual Reports in Computational Chemistry     Full-text available via subscription   (Followers: 3)
Annual Reports Section A (Inorganic Chemistry)     Full-text available via subscription   (Followers: 4)
Annual Reports Section B (Organic Chemistry)     Full-text available via subscription   (Followers: 8)
Annual Review of Chemical and Biomolecular Engineering     Full-text available via subscription   (Followers: 12)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 16)
Anti-Infective Agents     Hybrid Journal   (Followers: 3)
Antiviral Chemistry and Chemotherapy     Hybrid Journal   (Followers: 1)
Applied Organometallic Chemistry     Hybrid Journal   (Followers: 7)
Applied Spectroscopy     Full-text available via subscription   (Followers: 22)
Applied Surface Science     Hybrid Journal   (Followers: 28)
Arabian Journal of Chemistry     Open Access   (Followers: 6)
ARKIVOC     Open Access   (Followers: 2)
Asian Journal of Biochemistry     Open Access   (Followers: 1)
Atomization and Sprays     Full-text available via subscription   (Followers: 4)
Australian Journal of Chemistry     Hybrid Journal   (Followers: 7)
Autophagy     Hybrid Journal   (Followers: 2)
Avances en Quimica     Open Access   (Followers: 1)
Biochemical Pharmacology     Hybrid Journal   (Followers: 10)
Biochemistry     Full-text available via subscription   (Followers: 326)
Biochemistry Insights     Open Access   (Followers: 6)
Biochemistry Research International     Open Access   (Followers: 6)
BioChip Journal     Hybrid Journal  
Bioinorganic Chemistry and Applications     Open Access   (Followers: 9)
Bioinspired Materials     Open Access   (Followers: 5)
Biointerface Research in Applied Chemistry     Open Access   (Followers: 2)
Biointerphases     Open Access   (Followers: 1)
Biology, Medicine, & Natural Product Chemistry     Open Access   (Followers: 1)
Biomacromolecules     Full-text available via subscription   (Followers: 19)
Biomass Conversion and Biorefinery     Partially Free   (Followers: 10)
Biomedical Chromatography     Hybrid Journal   (Followers: 6)
Biomolecular NMR Assignments     Hybrid Journal   (Followers: 3)
BioNanoScience     Partially Free   (Followers: 5)
Bioorganic & Medicinal Chemistry     Hybrid Journal   (Followers: 120)
Bioorganic & Medicinal Chemistry Letters     Hybrid Journal   (Followers: 85)
Bioorganic Chemistry     Hybrid Journal   (Followers: 10)
Biopolymers     Hybrid Journal   (Followers: 18)
Biosensors     Open Access   (Followers: 2)
Biotechnic and Histochemistry     Hybrid Journal   (Followers: 1)
Bitácora Digital     Open Access  
Boletin de la Sociedad Chilena de Quimica     Open Access  
Bulletin of the Chemical Society of Ethiopia     Open Access   (Followers: 2)
Bulletin of the Chemical Society of Japan     Full-text available via subscription   (Followers: 24)
Bulletin of the Korean Chemical Society     Hybrid Journal   (Followers: 1)
C - Journal of Carbon Research     Open Access   (Followers: 3)
Cakra Kimia (Indonesian E-Journal of Applied Chemistry)     Open Access  
Canadian Association of Radiologists Journal     Full-text available via subscription   (Followers: 3)
Canadian Journal of Chemistry     Hybrid Journal   (Followers: 10)
Canadian Mineralogist     Full-text available via subscription   (Followers: 5)
Carbohydrate Research     Hybrid Journal   (Followers: 26)
Carbon     Hybrid Journal   (Followers: 68)
Catalysis for Sustainable Energy     Open Access   (Followers: 7)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 7)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysts     Open Access   (Followers: 8)
Cellulose     Hybrid Journal   (Followers: 7)
Cereal Chemistry     Full-text available via subscription   (Followers: 5)
ChemBioEng Reviews     Full-text available via subscription   (Followers: 1)
ChemCatChem     Hybrid Journal   (Followers: 8)
Chemical and Engineering News     Free   (Followers: 15)
Chemical Bulletin of Kazakh National University     Open Access  
Chemical Communications     Full-text available via subscription   (Followers: 70)
Chemical Engineering Research and Design     Hybrid Journal   (Followers: 25)
Chemical Research in Chinese Universities     Hybrid Journal   (Followers: 3)
Chemical Research in Toxicology     Full-text available via subscription   (Followers: 21)
Chemical Reviews     Full-text available via subscription   (Followers: 184)
Chemical Science     Open Access   (Followers: 22)
Chemical Technology     Open Access   (Followers: 16)
Chemical Vapor Deposition     Hybrid Journal   (Followers: 5)
Chemical Week     Full-text available via subscription   (Followers: 8)
Chemie in Unserer Zeit     Hybrid Journal   (Followers: 56)
Chemie-Ingenieur-Technik (Cit)     Hybrid Journal   (Followers: 24)
ChemInform     Hybrid Journal   (Followers: 8)
Chemistry & Biodiversity     Hybrid Journal   (Followers: 6)
Chemistry & Biology     Full-text available via subscription   (Followers: 30)
Chemistry & Industry     Hybrid Journal   (Followers: 5)
Chemistry - A European Journal     Hybrid Journal   (Followers: 146)
Chemistry - An Asian Journal     Hybrid Journal   (Followers: 15)
Chemistry and Materials Research     Open Access   (Followers: 20)
Chemistry Central Journal     Open Access   (Followers: 4)
Chemistry Education Research and Practice     Free   (Followers: 5)
Chemistry in Education     Open Access   (Followers: 9)
Chemistry International     Hybrid Journal   (Followers: 2)
Chemistry Letters     Full-text available via subscription   (Followers: 42)
Chemistry of Materials     Full-text available via subscription   (Followers: 246)
Chemistry of Natural Compounds     Hybrid Journal   (Followers: 9)
Chemistry World     Full-text available via subscription   (Followers: 22)
Chemistry-Didactics-Ecology-Metrology     Open Access   (Followers: 1)
ChemistryOpen     Open Access   (Followers: 2)
Chemkon - Chemie Konkret, Forum Fuer Unterricht Und Didaktik     Hybrid Journal  
Chemoecology     Hybrid Journal   (Followers: 4)
Chemometrics and Intelligent Laboratory Systems     Hybrid Journal   (Followers: 14)
Chemosensors     Open Access  
ChemPhysChem     Hybrid Journal   (Followers: 10)
ChemPlusChem     Hybrid Journal   (Followers: 2)
ChemTexts     Hybrid Journal  
CHIMIA International Journal for Chemistry     Full-text available via subscription   (Followers: 2)
Chinese Journal of Chemistry     Hybrid Journal   (Followers: 6)
Chinese Journal of Polymer Science     Hybrid Journal   (Followers: 10)
Chromatographia     Hybrid Journal   (Followers: 24)
Clay Minerals     Full-text available via subscription   (Followers: 10)
Cogent Chemistry     Open Access  
Colloid and Interface Science Communications     Open Access  
Colloid and Polymer Science     Hybrid Journal   (Followers: 10)
Colloids and Surfaces B: Biointerfaces     Hybrid Journal   (Followers: 6)
Combinatorial Chemistry & High Throughput Screening     Hybrid Journal   (Followers: 4)
Combustion Science and Technology     Hybrid Journal   (Followers: 19)
Comments on Inorganic Chemistry: A Journal of Critical Discussion of the Current Literature     Hybrid Journal   (Followers: 2)
Composite Interfaces     Hybrid Journal   (Followers: 6)
Comprehensive Chemical Kinetics     Full-text available via subscription   (Followers: 2)
Comptes Rendus Chimie     Full-text available via subscription  
Comptes Rendus Physique     Full-text available via subscription   (Followers: 1)
Computational and Theoretical Chemistry     Hybrid Journal   (Followers: 9)
Computational Biology and Chemistry     Hybrid Journal   (Followers: 11)
Computational Chemistry     Open Access   (Followers: 2)
Computers & Chemical Engineering     Hybrid Journal   (Followers: 9)
Coordination Chemistry Reviews     Full-text available via subscription   (Followers: 3)
Copernican Letters     Open Access   (Followers: 1)
Corrosion Series     Full-text available via subscription   (Followers: 6)
Critical Reviews in Biochemistry and Molecular Biology     Hybrid Journal   (Followers: 5)
Croatica Chemica Acta     Open Access  
Crystal Structure Theory and Applications     Open Access   (Followers: 4)
CrystEngComm     Full-text available via subscription   (Followers: 13)
Current Catalysis     Hybrid Journal   (Followers: 2)
Current Metabolomics     Hybrid Journal   (Followers: 5)
Current Opinion in Colloid & Interface Science     Hybrid Journal   (Followers: 9)
Current Opinion in Molecular Therapeutics     Full-text available via subscription   (Followers: 18)
Current Research in Chemistry     Open Access   (Followers: 8)
Current Science     Open Access   (Followers: 64)
Dalton Transactions     Full-text available via subscription   (Followers: 23)
Detection     Open Access   (Followers: 2)
Developments in Geochemistry     Full-text available via subscription   (Followers: 2)
Diamond and Related Materials     Hybrid Journal   (Followers: 12)
Dislocations in Solids     Full-text available via subscription  
Doklady Chemistry     Hybrid Journal  
Drying Technology: An International Journal     Hybrid Journal   (Followers: 4)
Eclética Química     Open Access   (Followers: 1)
Ecological Chemistry and Engineering S     Open Access   (Followers: 3)
Ecotoxicology and Environmental Contamination     Open Access  
Educación Química     Open Access   (Followers: 1)
Education for Chemical Engineers     Hybrid Journal   (Followers: 5)
EJNMMI Radiopharmacy and Chemistry     Open Access  

        1 2 3 | Last

Journal Cover Applied Organometallic Chemistry
  [SJR: 0.632]   [H-I: 58]   [7 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 0268-2605 - ISSN (Online) 1099-0739
   Published by John Wiley and Sons Homepage  [1589 journals]
  • Current Applications of Suzuki–Miyaura Coupling Reaction in The Total
           Synthesis of Natural Products: An update
    • Authors: Afsaneh Taheri Kal Koshvandi; Majid M. Heravi, Tayebeh Momeni
      Abstract: Suzuki-Miyaura Coupling Reaction (SMCR) has been extensively used in the total synthesis of natural products. We underscored these achievements in a report published in Tetrahedron up to 2012. Since then, there has been tremendous growth in this field and numerous articles have been published after 2012. In this review, we tried to go insight and highlight the current developments in the applications of SMCR as a key and strategic step (steps) in the total synthesis of biologically active natural products accomplished and reported from 2012 till date.Suzuki-Miyaura Coupling Reaction (SMCR) has been extensively used in the total synthesis of natural products. SMCR is an organic reaction, classified as an important cross coupling reaction, where the coupling partners are an appropriate boronic acid and a suitable organohalide, catalyzed by a palladium(0) complex. In this review, we try to underscore the current developments in the applications of SMCR as a key and strategic step (steps) in the total synthesis of natural products, published from 2012 till date.
      PubDate: 2018-01-19T03:50:47.018524-05:
      DOI: 10.1002/aoc.4210
       
  • Synthesis of V5+-doped Ag/AgCl photocatalysts with enhanced visible light
           photocatalytic activity
    • Authors: Caiping Guo; Limin Song, Yamiao Li, Shujuan Zhang
      Abstract: V5+-doped Ag/AgCl photocatalysts were prepared via the ion exchange method. The catalysts were characterized using X-ray diffractometry, transmission electron microscopy, and energy-dispersive X-ray, X-ray photoelectron, Fourier transform infrared and ultraviolet–visible spectroscopies. The V5+-doped Ag/AgCl photocatalysts show much higher photocatalytic activities than Ag/AgCl under visible light irradiation for methyl orange (MO) decomposition. Especially, the 2.0 wt% V5+-doped Ag/AgCl photocatalyst shows the highest photocatalytic activity and also high stability after five cycles. The MO degradation rate during each cycle is almost maintained at 97%. Electron spin resonance spectroscopy and radical trapping experiments reveal that holes play an important role in the photocatalytic process.Herein, we reported a novel photocatalyst of V5+-doped Ag/AgCl. Our results demonstrated that the 2.0 wt% V5+-doped Ag/AgCl is an excellent photocatalytic activity for degrading MO. The possible photodegradation mechanism were discussed by ESR spectroscopy and the radical trapping experiments, results showing that the hole (h+) played a more important role in the photocatalytic process.
      PubDate: 2018-01-19T03:46:24.597397-05:
      DOI: 10.1002/aoc.4237
       
  • Synthesis and properties of m-ferrocenylbenzoylthiadiazole derivatives
    • Authors: Biao Li; Xinju Zhu, Yuan Guo, Ya-Ping Ren, Zhao-Dong Jia, Jing-Na Wei, Dong-Xia Fu, Yan Xu, Xin-Qi Hao
      Abstract: A series of m-ferrocenylbenzoylthiadiazole compounds, namely FcL1–FcL7, were synthesized using 3-ferrocenylbenzoic acid and 2-amino-5-aryl-1,3,4-thiadiazole as raw materials. These compounds were characterized using infrared and NMR spectroscopies and elemental analysis. The crystal structure of FcL7 was determined using X-ray diffraction. The electrochemical behaviors of FcL1–FcL7 revealed that the redox reactions on the surface of electrodes were reversible with a single-electron mechanism. Also, FcL1–FcL7 demonstrated certain redox responses to Pb2+ and Zn2+. Moreover, FcL5–FcL7 exhibited good inhibition against human esophageal cancer cells in anticancer activity tests.Seven m-ferrocenylbenzoylthiadiazole compounds, FcL1–FcL7, were synthesized and characterized. The crystal structure of FcL7 was determined using X-ray diffraction. The electrochemical properties and anticancer activities were investigated. These compounds showed a certain redox response to Pb2+ and Zn2+. FcL5–FcL7 exhibited good inhibition against human esophageal cancer cells.
      PubDate: 2018-01-19T03:40:56.349606-05:
      DOI: 10.1002/aoc.4265
       
  • Synthesis, properties and mechanism of photodegradation of core–shell
           structured upconversion luminescent NaYF4:Yb3+,Er3+@BiOCl
    • Authors: Shiyu Zhou; Qiyan Zhang, Deqiang Zhao, Wenjuan Zong, Zihong Fan, Yaofang Sun, Xuan Xu
      Abstract: Microspherical bismuth oxychloride (BiOCl) can only utilize ultraviolet (UV) light to promote photocatalytic reactions. To overcome this limitation, a uniform and thin BiOCl nanosheet was synthesized with a particle size of about 200 nm. As results of UV–visible diffuse reflectance spectroscopy showed, the band gap of this nanostructure was reduced to 2.78 eV, indicating that the BiOCl nanosheet could absorb and utilize visible light. Furthermore, the upconversion material NaYF4 doped with rare earth ions Yb3+ and Er3+ emitted visible light at 410 nm following excitation with near-infrared (NIR) light (980 nm), which could be utilized by BiOCl to produce a photocatalytic reaction. To produce a high-efficiency photocatalyst (NaYF4:Yb3+,Er3+@BiOCl), BiOCl-loaded NaYF4:Yb3+,Er3+ was successfully synthesized via a simple two-step hydrothermal method. The as-synthesized material was confirmed using X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy as well as other characterizations. The removal ratio of methylene blue by NaYF4:Yb3+,Er3+@BiOCl was much higher than that of BiOCl alone. Recycling experiments verified the stability of NaYF4:Yb3+,Er3+@BiOCl, which demonstrated excellent adsorption, strong visible-light absorption and high electron–hole separation efficiency. Such properties are expected to be useful in practical applications, and a further understanding of the NIR-light-responsive photocatalytic mechanism of this new catalytic material would be conducive to improving its structural design and function.Uniform, thin BiOCl nanosheets were synthesized, and the band gap of this nanostructure was reduced to 2.78 eV. The BiOCl nanosheets were doped on NaYF4:Yb3+,Er3+ and the resulting composite could play a role as a photocatalyst under 980 nm excitation because of the upconversion luminescent material. The photocatalytic degradation efficiency for methylene blue (MB) was 78%, which was superior to that of other catalysts.
      PubDate: 2018-01-19T03:37:42.207049-05:
      DOI: 10.1002/aoc.4230
       
  • Selective hydrogenation of aromatic compounds using modified iridium
           nanoparticles
    • Authors: He-yan Jiang; Jie Xu, Bin Sun
      Abstract: Till now, Ionic liquid-stabilized metal nanoparticles were investigated as catalytic materials, mostly in the hydrogenation of simple substrates like olefins or arenes. The adjustable hydrogenation products of aromatic compounds, including quinoline and relevant compounds, aromatic nitro compounds, aromatic ketones as well as aromatic aldehydes, are always of special interest, since they provide more choices for additional derivatization. Iridium nanoparticles (Ir NPs) were synthesized by the H2 reduction in imidazolium ionic liquid. TEM indicated that the Ir NPs is worm-like shape with the diameter around 12.2 nm and IR confirmed the modification of phosphine-functionalized ionic liquids (PFILs) to the Ir NPs. With the variation of the modifier, solvent and reaction temperature, substrate like quinoline and relevant compounds, aromatic nitro compounds, aromatic ketones as well as aromatic aldehydes could be hydrogenated by Ir NPs with interesting adjustable catalytic activity and chemoselectivity. Ir NPs modified by PFILs are simple and efficient catalysts in challenging chemoselective hydrogenation of quinoline and relevant compounds, aromatic nitro compounds, aromatic ketones as well as aromatic aldehydes. The activity and chemoselectivity of the Ir NPs could be obviously impacted or adjusted by altering the modifier, solvent and reaction temperature.Iridium nanoparticles (Ir NPs) were synthesized by the H2 reduction in imidazolium ionic liquid. TEM indicated that the Ir NPs is worm-like shape with the diameter around 12.2 nm, IR confirmed the modification of phosphine-functionalized ionic liquids to the Ir NPs. With the variation of the modifier, solvent and reaction temperature, substrate like quinoline and relevant compounds, aromatic nitro compounds, aromatic ketones as well as aromatic aldehydes could be hydrogenated by Ir NPs with interesting adjustable catalytic activity and chemoselectivity.
      PubDate: 2018-01-19T03:35:37.797334-05:
      DOI: 10.1002/aoc.4260
       
  • Palladium nanoparticles immobilized on cyclodextrin-decorated halloysite
           nanotubes: Efficient heterogeneous catalyst for promoting copper- and
           ligand-free Sonogashira reaction in water–ethanol mixture
    • Authors: Samahe Sadjadi
      Abstract: Combining the excellent features of halloysite nanoclay and cyclodextrin, a novel hybrid system was designed and synthesized based on covalent attachment of tosylated cyclodextrin to thiosemicarbazide-functionalized halloysite nanoclay and used for the immobilization of Pd nanoparticles. The resulting hybrid, Pd@HNTs-T-CD, was then characterized using various techniques, and successfully used for promoting copper- and ligand-free Sonogashira coupling reactions of halobenzenes and acetylenes in a mixture of water and ethanol. Notably, under Pd@HNTs-T-CD catalysis, the reaction could proceed in relatively short reaction time to furnish the corresponding products in high yields. Additionally, the catalyst was recyclable and could be simply recovered and reused for several reaction runs. Results also established negligible leaching of Pd, indicating the efficiency of HNTs-T-CD for embedding Pd nanoparticles.Combining the excellent features of halloysite nanoclay and cyclodextrin, a novel hybrid system was synthesized and used for immobilization of Pd nanoparticles. The resulting hybrid, Pd@HNTs-T-CD, was successfully used for promoting copper and ligand-free Sonogashira coupling reaction. Notably, the catalyst was recyclable and could be simply recovered and recycled up to several reaction runs with low Pd leaching and loss of the catalytic activity.
      PubDate: 2018-01-19T03:31:36.124929-05:
      DOI: 10.1002/aoc.4211
       
  • Phosphorus-nitrogen compounds. Part 39. Syntheses and Langmuir-Blodgett
           thin films and antimicrobial activities of N/N and N/O
           spirocyclotriphosphazenes with monoferrocenyl pendant arm
    • Authors: Nuran Asmafiliz; Mehmet Civan, Arda Özben, Zeynel Kılıç, Nagehan Ramazanoğlu, Leyla Açık, Tuncer Hökelek
      Abstract: The Cl substitution reactions of the N/N (1-3) and N/O (4 and 5) spirocyclic monoferrocenylphosphazenes with 1,4-dioxa-8-azaspiro[4,5]decane (DASD) produce the mono- (1a-5a), geminal- (1b-5b) and tetrakis-DASD-substituted ferrocenylspirocyclotriphosphazenes (1c-5c). The mono- and geminal-DASD-substituted phosphazenes have two and one stereogenic P-centers, respectively. The structures of the compounds were established by spectroscopic techniques. The molecular structures of 3a and 2b were evaluated using X-ray crystallography. Additionally, the ultrathin and highly ordered Langmuir-Blodgett (LB) films of 3a and 2b were also prepared. The characterizations of the LB films were done using p-polarized grazing angle (GAIR) and horizontal attenuated total reflectance (HATR) techniques. On the other hand, the antimicrobial activities of the eight phosphazene derivatives against G(+) and G(-) bacteria and fungi were investigated. Furthermore, the interactions between the compounds and plasmid DNA were studied by agarose gel electrophoresis.The new partly and fully-DASD-substituted spirocyclotriphosphazenes were prepared. The structures of these compounds were determined. The ultrathin and highly ordered LB films of the two compounds were fabricated. The new phosphazenes were screened for antimicrobial activity. The interactions between the compounds and pBR322 plasmid DNA were investigated.
      PubDate: 2018-01-17T00:06:18.051759-05:
      DOI: 10.1002/aoc.4223
       
  • Preparation and Characterization of Ni-Modified Graphene Oxide Complex as
           an Efficient Catalyst for the Synthesis of Sulfides via Reaction of
           Arylhalides with S8 or Thiourea
    • Authors: Raziyeh Ghafouri-Nejad; Maryam Hajjami, Razieh Nejat
      Abstract: In this work, complex of Ni-modified graphene oxide was prepared and characterized using FT-IR spectroscopy, SEM, XRD, TGA and ICP-OES techniques. This compound used as an efficient and recoverable catalyst for the C–S coupling reaction using sulfur-transfer reagents (S8 or thiourea). The catalyst was easily separated using a simple filtration and reusable without significant loss of their catalytic efficiency.Complex of Ni-Modified Graphene Oxide was prepared and characterized using FT-IR spectroscopy, SEM, XRD, TGA and ICP-OES techniques. This compound used as an efficient and recoverable catalyst for the C–S coupling reaction using sulfur-transfer reagents (S8 or thiourea).
      PubDate: 2018-01-16T23:55:54.947309-05:
      DOI: 10.1002/aoc.4248
       
  • Oxazolidine copper complexes: Synthesis, characterization and superoxide
           dismutase activity of copper(II) complexes with oxazolidine ligands
           derived from hydroxyquinoline carboxaldehyde
    • Authors: Joice Ceolin; Josiéli Demetrio Siqueira, Francisco Mainardi Martins, Paulo C. Piquini, Bernardo A. Iglesias, Davi F. Back, Gelson Manzoni de Oliveira
      Abstract: This work describes the synthesis of copper(II) complexes, their identification using spectroscopic and electrochemical methods, structural characterization with X-ray diffraction and density functional theory calculations (DFT), as well as their catalytic activity mimicking that of superoxide dismutase. Structural analysis revealed the formation of complexes with cyclization of ligands L1 and L2 with the formation of a heterocycle, 1,3-oxazolidine. The DFT calculations confirmed this trend by stabilizing with lower energy. In addition, evaluations of mimetic enzymatic activity of complexes C1, C2, C3 and C4 revealed promising IC50 values compared to other results seen in the literature (IC50 = 0.22, 0.328, 0.55 and 0.92). Also, calf thymus DNA interactive experiments using UV–visible spectroscopy were conducted in the presence of the copper(II) complexes.Reported are the synthesis of copper(II) complexes, their identification through spectroscopic and electrochemical methods, structural characterization with X-ray diffraction and density functional theory calculations (DFT), as well as their catalytic activity mimicking that of superoxide dismutase – SOD. Calf thymus DNA interactive experiments were also conducted in the presence of the Cu(II) complexes.
      PubDate: 2018-01-16T23:51:50.389441-05:
      DOI: 10.1002/aoc.4218
       
  • Coordination modes of multidentate azodye ligand derived from
           4,4′-methylenedianiline towards some transition metal ions: Synthesis,
           spectral characterization, thermal investigation and biological activity
    • Authors: Saeyda A. Abouel-Enein; Sanaa M. Emam, Eman Monir
      Abstract: Nine new azodye metal complexes of Mn(II), Co(II), Ni(II), Cu(II), Cr(III), Fe(III), Ru(III), Hf(IV) and Zr(IV) ions have been prepared via the reaction of 5,5′-((1E,1′E)-(methylenebis(1,4-phenylene))bis(diazene-2,1-diyl))bis(6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(5H)-one) (H4L) with the corresponding metal salts affording sandwich (1 L:1 M), mononuclear (2 L:1 M), binuclear (1 L,2 M) and tetranuclear (1 L,4 M) complexes. Elemental analyses, spectral methods, magnetic moment measurements and thermal studies were utilized to confirm the mode of bonding and geometrical structure for the ligand and its metal complexes. Infrared spectral data show that the H4L ligand chelates with some metal ions in keto–enol–thione or keto–thione manner. It behaves in a neutral/dibasic tetradentate fashion in sandwich and binuclear complexes. Also, it acts as a neutral bidentate moiety in the Cr(III) complex. The spectra reveal that azo group participates in chelation in all complexes. Octahedral geometry was suggested for all chelates but the Cu(II) complex with square planar geometry. The thermal stability and decomposition of the compounds were studied, the data showing that the thermal decomposition ended with metal or metal oxide mixed with carbon as final product. The electron spin resonance spectrum of the Cu(II) complex demonstrates that the free electron is located in the (dx2−y2) orbital. Measurements of biological activity against human cell lines Hep-G2 and MCF-7 reveal that the Cu(II) complex has a higher cytotoxicity in comparison to the free ligand and other metal complexes, with IC50 values of 6.10 and 5.2 μg ml−1, respectively, while the ligand has anti-tumour activity relative to some of the investigated metal complexes.5,5′-((1E,1E′)-(methylenebis(1,4-phylene)bis(diazene-2,1-diyl))bis(6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(5H)-one).
      PubDate: 2018-01-16T23:50:33.882728-05:
      DOI: 10.1002/aoc.4191
       
  • Organoselenium compounds containing pyrazole or phenylthiazole groups:
           Synthesis, structure, tin(IV) complexes and antiproliferative activity
    • Authors: Roxana A. Popa; Emilia Licarete, Manuela Banciu, Anca Silvestru
      Abstract: The diorganodiselenides (pzCH2CH2)2Se2 (1) and (PhtzCH2)2Se2 (2) were prepared by reacting Na2Se2 with 1-(2-bromoethyl)-1H-pyrazole and 4-(chloromethyl)-2-phenylthiazole, respectively, while the reactions between 1-(2-bromoethyl)-1H-pyrazole or 4-(chloromethyl)-2-phenylthiazole and the lithium organoselenolates [2-(Et2NCH2)C6H4]SeLi and [2-{O(CH2CH2)2NCH2}C6H4]SeLi in a 1:1 molar ratio resulted in the heteroleptic diorganoselenium(II) compounds [2-(Et2NCH2)C6H4](R)Se (R = pzCH2CH2 (3) or PhtzCH2 (5)) and [2-{O(CH2CH2)2NCH2}C6H4](R)Se (R = pzCH2CH2 (4) or PhtzCH2 (6)). The diorganotin(IV) bis(organoselenolato) derivatives of type R2Sn(SeCH2CH2pz)2 (R = 2-(Me2NCH2)C6H4 (7) or Me (8)) were obtained by reacting (pzCH2CH2)SeNa with the appropriate diorganotin(IV)dichloride in a 2:1 molar ratio. All compounds were investigated using NMR spectroscopy (1H, 13C, 77Se, 119Sn as appropriate) and ESI+ mass spectrometry. The molecular structures of 2 and 6 were determined using single-crystal X-ray diffraction. The formation of a 10–Se–3 hypercoordinated species was evidenced for 6 in the solid state, as a consequence of the C,N coordination behaviour of the 2-{O(CH2CH2)2NCH2}C6H4 group. Compounds 1, 7 and 8 were investigated for their antiproliferative activity towards the mouse colon carcinoma C26 cell line with the preliminary results showing a better activity than 5-fluorouracil.The diorganodiselenides (pzCH2CH2)2Se2 (1) and (PhtzCH2)2Se2 (2) and the heteroleptic diorganoselenium(II) species [2-(Et2NCH2)C6H4](R)Se [R = pzCH2CH2 (3) or PhtzCH2 (5)] and [2-{O(CH2CH2)2NCH2}C6H4](R)Se (R = pzCH2CH2 (4) and PhtzCH2 (6)] were prepared and structurally characterized. The diorganotin(IV) bis(organoselenolate)s of type R2Sn(CH2CH2pz)2 [R = 2-(Me2NCH2)C6H4 (7), Me (8)] are also described. 1 and 7 were investigated for their antiproliferative activity towards the mouse colon carcinoma C26 cell line.
      PubDate: 2018-01-16T23:40:28.713585-05:
      DOI: 10.1002/aoc.4252
       
  • Copper(I)-catalyzed multicomponent reactions in sustainable media
    • Authors: Robert Pawłowski; Ewelina Zaorska, Sebastian Staszko, Anna Szadkowska
      Abstract: Multicomponent reactions including Biginelli reaction and A3 coupling are useful synthetic methodologies as they can provide valuable intermediates and building blocks for the synthesis of bioactive natural compounds. The heterocyclic products of these transformations represent antibacterial, antitumor or anti-inflammatory properties. In presented study, copper-mediated protocols for Biginelli reaction and A3 coupling in sustainable solvents were reported. At first, charged NHC copper complexes were synthesized in few steps and characterized using spectroscopic methods followed by preliminary activity tests in sustainable media. Later in this study, Biginelli reaction and A3 coupling were proceeded using prepared copper catalytic systems under mild conditions. Desired nitrogen-bearing products were obtained with moderate to very high yields. Some attempts to recycle one of the received NHC copper initiators were also investigated.Two NHC copper(I) complexes containing charged ligands have been synthesized and characterized using spectroscopic techniques. Further investigations on catalytic activity of prepared initiators in multicomponent reactions were carried out in sustainable solvents. The efficiency of presented copper catalytic systems was confirmed by the compatibility with a board range of functional groups used in the products of Biginelli reaction and A3 coupling reaction.
      PubDate: 2018-01-16T23:30:29.230934-05:
      DOI: 10.1002/aoc.4256
       
  • Multispectroscopic DNA interaction and Docking studies
    • Authors: B. Shekhar; P. Vasantha, B. Sathish Kumar, P.V. Anantha Lakshmi
      Abstract: Two new water soluble oxovanadium(IV) complexes with formulae Na[VO(his)(met)SO4] (1) and Na[VO(gly)(met)SO4] (2), (gly=glycine his=histidine, and met=metformin) were synthesized and characterized by LCMS, UV-Visible absorption, infrared spectra, magnetic moment, elemental analysis, thermal analysis and electronic spectral studies. The metal center was found in an octahedral geometry. DNA binding interaction of these complexes with CT DNA has been explored by UV-Visible absorption, fluorescence, viscosity measurements and cleavage studies. Finally the binding of the complexes with CT-DNA could be surface binding, mainly in the groove binding. The complexes were docked in to B-DNA sequence, 5’(D*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*T)-3’ retrieved from protein data bank (PDB ID: 423D), using Discovery Studio 2.1 software.Multispectroscopic DNA interaction studies suggest that the two water soluble Ternary Oxovanadium(IV)-Metformin-Glycine/Histidine complexes bind to DNA via groove binding. Molecular docking with B-DNA indicates that both the compounds bound within the binding site pocket of metformin similar binding pattern with one of the binding site (DG19) nucleotide residue.
      PubDate: 2018-01-16T23:27:38.870487-05:
      DOI: 10.1002/aoc.4254
       
  • Au-dimercaprol functionalized cellulose aerogel: Synthesis,
           characterization and catalytic application
    • Authors: Sajjad Keshipour; Masoumeh Khezerloo
      Abstract: A new derivative of cellulose aerogel was prepared via functionalization of cellulose with dimercaprol. Dimercaprol, as a chelating agent of Au(III), was applied for the loading of Au(III) on cellulose aerogel. The new organogold compound after characterization was used as an efficient heterogeneous catalyst in the oxidation reactions of aliphatic alcohols, benzyl alcohol, and ethylbenzene. Excellent selectivities and good conversions were obtained in the green oxidation reactions of alcohols and ethylbenzene. The high porosity of cellulose aerogel led to the good conversions with the low catalyst amounts. The significance of the presented work is the introducing of an environmentally benign process for the oxidation reactions based on a biocompatible catalyst.Cellulose aerogel were modified with dimercaprol, and Au(III). The new biocomposite showed good catalytic activity in the oxidation reactions of some organic substrates. High conversions and excellent selectivities were observed for the oxidation of alcohols and ethylbenzene in the green oxidation reaction conditions.
      PubDate: 2018-01-16T23:27:14.402637-05:
      DOI: 10.1002/aoc.4255
       
  • Green synthesis of Fe3O4@SiO2-Ag magnetic nanocatalyst using safflower
           extract and its application as recoverable catalyst for reduction of dye
           pollutants in water
    • Authors: Pourya Mohammadi; Hassan Sheibani
      Abstract: This paper reports the green and in situ preparation of Fe3O4@SiO2-Ag magnetic nanocatalyst synthesized using safflower (Carthamus tinctorius L.) flower extract without the addition of any stabilizers or surfactants. The catalytic performance of the resulting nanocatalyst was examined for the reduction of 4-nitrophenol (4-NP), methylene blue (MB) and methyl orange (MO) in an environment-friendly medium at room temperature. The main factors such as pH, temperature and amount of catalyst influencing the nanocatalyst performance were studied. The apparent rate constants for 4-NP, MO and MB reduction were calculated, being 0.756 min−1, 0.064 s−1 and 0.09 s−1, respectively. The catalyst was recovered using an external magnet and reused several times with negligible loss of catalytic activity. The as-synthesized nanoparticles were characterized using powder X-ray diffraction, transmission electron microscopy, UV–visible, Fourier transform infrared and inductively coupled plasma atomic emission spectroscopies, dynamic light scattering and vibrating sample magnetometry.Fe3O4@SiO2-Ag nanocatalyst was prepared by using safflower flower extract and characterized by X-ray powder diffraction, transmission electron microscopy, UV-Vis spectroscopy, Fourier transform infrared spectra, Inductively coupled plasma atomic emission spectroscopy, dynamic light scattering and vibration sample magnetometer. This nanocatalyst was used for the reduction of dye pollutants in water such 4-nitrophenol (4-NP), methylene blue (MB) and methyl orange (MO). The nanocatalyst is stable and reusable.
      PubDate: 2018-01-16T23:26:23.013265-05:
      DOI: 10.1002/aoc.4249
       
  • Novel Pyrazoline-based Organometallic Compounds Containing Ferrocenyl and
           Quinoline units: Synthesis, Characterization and Microbial
           susceptibilities
    • Authors: Humaira Parveen; Raedah Aiyed Suliman Alatawi, Meshari A. Alsharif, Mohammed Issa Alahmdi, Sayeed Mukhtar, Salman Ahmad Khan, Sadaf Hasan, Asad U. Khan
      Abstract: Some novel pyrazoline-based organometallic compounds were synthesized as new leads in antimicrobial chemotherapy. The structures of compounds were elucidated by different spectroscopic techniques and elemental analyses. All compounds were investigated for in vitro antimicrobial studies against fifteen ATTC bacterial and fungal strains. The microbial susceptibility of these compounds revealed that all the tested compounds gave good minimum inhibitory concentration (MIC) values against the tested organisms that are either similar or even better than the reference drugs amoxicillin and fluconazole, which gave MIC values 8-64 μg/ml against bacterial and 64 μg/ml against fungal strains, respectively. Among all compounds, compound (4d)1-(5-(4-chlorophenyl)-3-ferrocenyl-4,5-dihydropyrazol-1-yl)-2-quinolin-8-yloxy) ethanone, emerged out the most promising antimicrobial organometallic derivative with MIC values against all the strains ranging from 8-32 μg/ml. Other compounds gave a range of MIC values between 16-64 μg/ml against S. bovis, 16-32 μg/ml against E. coli, and C. tropicalis except compound (4d) which gave MIC 8 μg/ml against S. bovis and E. coli, whereas 32 μg/ml against C. tropicalis. Collectively, these compounds gave a lower MIC value between 32-64 μg/ml against both of the biofilm forming strains namely, P. aeruginosa and S. mutans. The results of microbial susceptibility concluded that these novel organometallic compounds are new leads in antimicrobial chemotherapy and can be very useful for further optimization work on microbial chemotherapy.Novel pyrazoline-based organometallic compounds containing ferrocenyl and quinoline units were synthesized, well characterized and screened for microbial susceptibility. The results revealed that these compounds are new leads in antimicrobial chemotherapy as all the tested compounds gave an extraordinary minimum inhibitory concentration (MIC) than the reference drugs Amoxicillin and Fluconazole. Among all, compound (4d) was emerged as the most promising antimicrobial organometallic derivative.
      PubDate: 2018-01-16T23:20:38.104815-05:
      DOI: 10.1002/aoc.4257
       
  • Synthesis of crab type Aminomethyldiphosphine-Oxovanadium(IV) complexes
           supported on magnetic Nano particles: Selective and recoverable catalysts
           in vitamin K3 synthesis
    • Authors: Serhan Uruş; Mahmut Çaylar, Ferudun Koçer
      Abstract: Nano Fe3O4 particles were obtained in microvawe oven using closed system. Oxovanadium(IV) complexes of Fe3O4@SiO2@(aminomethylphosphine) type ligands were synthesized and characterized using SEM, EDX, TEM, UV-Visible, XRD, FT-IR and TG/DTA techniques. Catalytic properties of the synthesized pincer type oxovanadium(IV)-aminomethylphosphine complexes supported on magnetic nano structure were investigated in the synthesis of 2-methyl-1, 4-naphthoquinone (Vitamin K3, menadione, 2MNQ) from 2-methyl naphthalene (2MN) in hydrogen peroxide, acetic acid and sulfuric acid. Magnetic-nano particle supported oxovanadium(IV)-aminomethylphosphine type complexes were very efficient catalysts with the 51.36-55.20 % selectivities in conversions of 89.78-95.01 %. Besides, the hetergeneous complexes were very active in five cycling tests on avarage evaluated in the reusability.Fe3O4@SiO2@(aminomethylphosphine)-oxovanadium(IV) type complexes active catalyst in vitamin K3 (2-methyl-1, 4-naphthoquinone) synthesis.
      PubDate: 2018-01-16T23:16:01.869124-05:
      DOI: 10.1002/aoc.4219
       
  • Anticancer platinum-based complexes with non-classical structures
    • Authors: Linxiang Cai; Congtao Yu, Linkui Ba, Qinghua Liu, Yunxu Qian, Bo Yang, Chuanzhu Gao
      Abstract: Although classical platinum drugs such as cisplatin, carboplatin and oxaliplatin play a vitally important role in cancer treatment, nonselective distribution of platinum drugs in normal and tumor cells can induce serious gastrointestinal reaction, nephrotoxicity, ototoxicity, neurotoxicity and cross resistance, limiting their applications. Over the past few years, a great number of platinum complexes of non-classical structures have been extensively investigated and evaluated in vitro and in vivo, some of them exhibiting considerable activity. In this review, platinum-based complexes with non-classical structures which have anticancer potential are described and several representative examples are discussed with their mechanism of action.Classical platinum drugs play an important role in treatment of solid neoplasms, but have various defects such as toxic side effects and drug resistance. Therefore, the search for less toxic and more effective novel platinum derivatives is the subject of intensive research. This review reports non-classical platinum complexes with their structures and characteristics for overcoming some difficult problems in cancer treatment, to maximize antitumor effect and minimize toxic side effects and drug resistance.
      PubDate: 2018-01-11T03:16:45.453851-05:
      DOI: 10.1002/aoc.4228
       
  • Hybridization of Al2O3 microspheres and acrylic ester resins as a
           synergistic absorbent for selective oil and organic solvent absorption
    • Authors: Tao Zhang; Xuejie Yue, Dongya Yang, Qing Guo, Fengxian Qiu, Zhangdi Li
      Abstract: In this study, we have focused on the synthesis, characterization, and oil absorption properties of Al2O3 microspheres/acrylic ester resin (AER) hybrids. The Al2O3 microspheres are prepared by a combined hydrothermal and sintering processes, followed by surface modification with silane coupling agent (KH 570). The Al2O3 microspheres/AER hybrids with a rough surface are synthesized by a microwave polymerization route by using modified Al2O3 microspheres as modifiers. In this hybrid materials system, the Al2O3 microspheres with porous structures may provide fast oil absorption due to the low oils absorption energy and short diffusion lengths. The resin hybrids exhibited reversible oils and organic solvents adsorption with maximum absorption capacities up to 29.85 g/g. This study suggests potential environmental advantage in using metal oxide microspheres in improving the oil absorption properties of oil-absorbing resins as absorbents for recovering oil and organic solvent from water.The synthesis, characterization, and oil absorption properties of Al2O3 microspheres/acrylic ester resin hybrids
      PubDate: 2018-01-11T03:16:27.153344-05:
      DOI: 10.1002/aoc.4244
       
  • Nature of MoH···I bonds in Cp2Mo(L)H···I-C≡C-R Complexes (L=H, CN,
           PPh2, C(CH3)3; R=NO2, Cl, Br, H, OH, CH3, NH2)
    • Authors: Yaru Dang; Weihua Wang, Lingpeng Meng, Qingzhong Li, Xiaoyan Li
      Abstract: The nature of the MoH···I bond in Cp2Mo(L)H···I-C≡C-R (L= H, CN, PPh2, C(CH3)3; R=NO2, Cl, Br, H, OH, CH3, NH2) was investigated using electrostatic potential analysis, topological analysis of the electron density, energy decomposition analysis and natural bond orbital analysis. The calculated results show that MoH···I interactions in the title complexes belong to halogen-hydride bond, which is similar to halogen bonds, not hydrogen bonds. Different to the classical halogen bonds, the directionality of MoH···I bond is low; Although electrostatic interaction is dorminant, the orbital interactions also play important roles in this kind of halogen bond, and steric interactions are weak; the strength of H···I bond can tuned by the most positive electrostatic potential of the I atom. As the electron-withdrawing ability of the R substituent in the alkyne increases, the electrostatic potential maximum of the I atom increases, which enhances the strength of the H···I halogen bond, as well as the electron transfer.In contrast to classical halogen bonds, the MoH···I bond is lowly directional and orbital interaction is important.
      PubDate: 2018-01-11T03:11:15.873195-05:
      DOI: 10.1002/aoc.4258
       
  • (Benzyl isocyanide)gold(I) pyrimidine-2-thiolate complex: Synthesis and
           biological activity
    • Authors: Masood Fereidoonnezhad; Hamid R. Shahsavari, Elaheh Lotfi, Mojgan Babaghasabha, Motahareh Fakhri, Zeinab Faghih, Zahra Faghih, M. Hassan Beyzavi
      Abstract: The reaction of [(Me2S)AuCl] with an equimolar amount of benzyl isocyanide (PhCH2NC) ligand led to the formation of complex [(PhCH2NC)AuCl] (1). The solid-state structure of 1 was determined using the X-ray diffraction method. Through a salt metathesis reaction, the chloride ligand in 1 was replaced by pyrimidine-2-thiolate (SpyN−) to afford the complex [(PhCH2NC)Au(η1-S-Spy)] (2), which was characterized spectroscopically. The cytotoxic activities of 1 and 2 were evaluated against three human cancer cell lines: ovarian carcinoma (SKOV3), lung carcinoma (A549) and breast carcinoma (MCF-7). Complex 2 showed higher cytotoxicity than cisplatin against SKOV3 and MCF-7 cancer cell lines. It showed a strong anti-proliferative activity with IC50 of 7.80, 6.26 and 6.14 μM, compared with that measured for cisplatin which was 7.62, 12.36 and 11.47 μM, against A549, SKOV3 and MCF-7 cell lines, respectively. The induction of cellular apoptosis by 2 was also studied on MCF-7 cell line. Our results indicated that 2 could induce apoptosis in cancerous cells in a dose-dependent manner.Gold(I) complexes with isocyanide and thiolate ligands were prepared and studied for in vitro cytotoxic activity against three human cancer cell lines: ovarian carcinoma (SKOV3), lung carcinoma (A549) and breast carcinoma (MCF-7). Complexes 1 and 2 were also investigated for their apoptosis effect. Complex 2 exhibited higher cytotoxicity than cisplatin.
      PubDate: 2018-01-11T03:05:41.460952-05:
      DOI: 10.1002/aoc.4200
       
  • Nanostructured Pyrophosphate Na2PdP2O7-Catalyzed Suzuki-Miyaura
           Cross-Coupling Under Microwave Irradiation
    • Authors: Karim Dânoun; Younes Essamlali, Othmane Amadine, Rida Tabit, Aziz Fihri, Christophe Len, Mohamed Zahouily
      Abstract: Nanostructured palladium pyrophosphate (Na2PdP2O7) catalyst was synthesized and well characterized by using different techniques (TGA, XRD, SEM, TEM....). This nanocatalyst exhibited excellent catalytic activity in the synthesis of biaryl compounds via Suzuki-Miyaura cross-coupling to produce their corresponding products in good to excellent yields under mild conditions. The catalyst is recyclable and was recycled for four runs for the reaction of 4-bromoacetophenone with phenylboronic acid without appreciable loss of its catalytic activity.
      PubDate: 2018-01-11T03:02:22.472294-05:
      DOI: 10.1002/aoc.4232
       
  • Use of an efficient polystyrene-supported cerium catalyst for one-pot
           multicomponent synthesis of spiro-piperidine derivatives and click
           reactions in green solvent
    • Authors: Paramita Mondal; Swarbhanu Ghosh, Sabuj kanti Das, Asim Bhaumik, Debashis Das, Sk. Manirul Islam
      Abstract: One-pot multicomponent reactions are very demanding in synthetic organic chemistry. Here we report a new polystyrene-supported cerium catalyst (PS-Ce-amtp) obtained via an easy two-step procedure, which was thoroughly characterized using various techniques. PS-Ce-amtp catalyses the environmentally benign one-pot multicomponent synthesis of spiro-piperidine derivatives through the reaction of substituted aniline, cyclic active methylene compound and formaldehyde at room temperature. The catalyst also exhibits excellent catalytic activity in one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via click reaction between in situ generated azides (derived from anilines and amines) and terminal alkynes. The catalyst can be recovered easily after reaction and reused five times without significant loss in its catalytic activity. The advantageous features of this catalyst are atom economy, operational simplicity, short reaction times, easy handling and high recycling efficiency.A new and efficient polystyrene-supported cerium complex, PS-Ce-amtp, has been prepared for the synthesis of spiro-piperidine derivatives and of 1,4-disubstituted 1,2,3-triazoles. The complex showed high catalytic activity towards cyclo-condensation reactions and gave excellent yields in a green reaction pathway. The catalyst could be recovered easily and reused five times without significant loss of catalytic activity.
      PubDate: 2018-01-11T02:57:27.009088-05:
      DOI: 10.1002/aoc.4227
       
  • Copper-supported β-cyclodextrin-functionalized magnetic nanoparticles:
           Efficient multifunctional catalyst for one-pot ‘green’ synthesis of
           1,2,3-triazolylquinazolinone derivatives
    • Authors: Saeed Bahadorikhalili; Arsalan Ashtari, Leila Ma’mani, Parviz Rashidi Ranjbar, Mohammad Mahdavi
      Abstract: The green synthesis of 2-(4-((1-phenyl-1H-1,2,3-triazol-4-yl)oxy)phenyl)quinazolin-4(3H)-one derivatives is reported. The catalyst for this synthesis is copper-supported β-cyclodextrin-functionalized magnetic silica–iron oxide nanoparticles ([Cu@BCD@SiO2@SPION]). [Cu@BCD@SiO2@SPION] simultaneously catalyses ‘click’ reaction, oxidation of CN bond and multicomponent reaction. The desired 1,2,3-triazolylquinazolinone product is easily obtained in water at room temperature under mild reaction conditions. Another advantage of the catalyst is its reusability. It can simply be isolated using an external magnet and reused in reactions with no significant decrease in catalyst efficiency. Transmission electron microscopy, scanning electron microscopy, vibrating sample magnetometry and Fourier transform infrared spectroscopy are used for exact characterization of the [Cu@BCD@SiO2@SPION] catalyst.A novel catalyst based on copper-supported β-cyclodextrin-functionalized magnetic silica–iron oxide nanoparticles is prepared. The catalyst catalyzes ‘click’ reaction, CN bond oxidation, and multicomponent reaction, for the synthesis of 2-(4-((1-phenyl-1H-1,2,3-triazol-4-yl)oxy)phenyl) quinazolin-4(3H)-one derivatives. The products are prepared in water at room temperature under mild reaction conditions. Another advantage of the catalyst is its reusability, while can simply be isolated using an external magnet and reused in reactions with no significant decrease in catalyst efficiency.
      PubDate: 2018-01-11T02:56:15.22124-05:0
      DOI: 10.1002/aoc.4212
       
  • Theoretical insight into the photodeactivation pathway of the tetradentate
           Pt(II) complex: The π-conjugation effect
    • Authors: Ke Zuo; Yafei Luo, Xin Sun, Wei Shen, Dianyong Tang, Jianping Hu
      Abstract: In this work, density functional theory and time-dependent density functional theory were used to investigate the effects of π-conjugation of the ligand on the photophysical properties, radiative/nonradiative processes and phosphorescence quantum efficiency of tetradentate cyclometalated Pt (II) complex with carbazolyl-pyridine ligands PtNON. By simulating the absorption spectra and emission wavelengths, increasing the π-conjugation of the ligand could cause the absorption and emission wavelengths to red-shift. The results of the computation of key parameters in the radiative decay process, such as singlet-triplet splitting energy, transition dipole moment and spin-coupled matrix element between the lowest triplet and singlet excited states, showed that the expansion of π-conjugation on the carbazole ligand of PtNON resulted in reduction of these parameters, thereby reducing the radiation rate constant. The analyses of the PtNON nonradiative pathway also found that the high activation energy of PtNON made it one of the reasons for the high phosphorescence quantum yield. At the same time, enhancing the molecular orbital delocalization of the ligand further enlarged the energy barrier of the nonradiative pathway, and was conducive to the improvement of phosphorescence quantum yield.Expanding the π-conjugation of the main ligand results in a red-shift in the absorption and emission wavelength and a decrease of excitation energy and the radiative decay rate constant. It also reduces the matrix element between the T1 and S0 states, and enlarges activation energy barrier of the nonradiative process leading to a suppression of the thermally activated nonradiative photodeactivation. In general, increasing the π-conjugation can reduce the nonradiative rate constant and increase the phosphorescence quantum yield of the complexes.
      PubDate: 2018-01-11T02:53:46.31715-05:0
      DOI: 10.1002/aoc.4220
       
  • Cell-based studies of the first-in-class half-sandwich Ir(III) complex
           containing histone deacetylase inhibitor 4-phenylbutyrate
    • Authors: Pavel Štarha; Zdeněk Trávníček, Bohuslav Drahoš, Radovan Herchel, Zdeněk Dvořák
      Abstract: We report on a cytotoxic half-sandwich iridium(III) complex [Ir(η5-Cpph)(phen)(PB)]PF6 (1-PB), containing a monodentate coordinated O-donor 4-phenylbutyrato ligand (PB) belonging to the family of histone deacetylase inhibitors (HDACi); HCpph = (2,3,4,5-tetramethylcyclopenta-2,4-dien-1-yl)benzene, phen = 1,​10-phenanthroline. The solution behaviour studies indicated that complex 1-PB partially hydrolysed in the mixture of methanol and water (1:4, v/v), resulting in the release of the PB ligand. The extent of the PB ligand release increased in the presence of 2 molar equiv. of the reduced glutathione (GSH). Complex 1-PB exhibited comparable in vitro cytotoxicity against the cisplatin-sensitive (IC50 = 15.8 μM) and -resistant (IC50 = 13.0 μM) variants of the A2780 human ovarian carcinoma cells, while its potency against the MRC-5 human normal fibroblast cells was markedly lower (IC50 = 124.1 μM). The cytotoxicity studies revealed an ability of complex 1-PB to overcome the acquired resistance against cisplatin, with the resistance factor (RF = 0.8) being markedly lower than for complex 1-Cl (RF = 1.8) and cisplatin (RF = 2.9). The A2780 cell-based flow cytometry experiments showed different cell cycle modification induced by complex 1-PB and cisplatin, induction of production of reactive oxygen species, and higher mitochondria membrane potential depleted cell populations after the treatment by complex 1-PB as compared with cisplatin. In the cell-free assay, complex 1-PB inhibited the HDAC activity to ca 66% as compared to ca 74% valid for NaPB. The [Ir(η5-Cpph)(phen)(H2O)]2+ species (1-OH2), representing the hydrolysis product of both complexes 1-PB and 1-Cl, induced hydroxyl radical from the hydrogen peroxide, as proved by the EPR spin trapping studies with the 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO) spin trap.Exchange of the chlorido ligand by the HDAC inhibitor 4-phenylbutyrate (PB) in [Ir(η5-Cpph)(phen)(PB)]PF6 improved cytotoxicity against A2780 and A2780R cells.
      PubDate: 2018-01-11T02:50:41.087321-05:
      DOI: 10.1002/aoc.4246
       
  • α-Diimine nickel catalyst for copolymerization of hexene and acrylate
           monomers activated by different cocatalysts
    • Authors: Sajad Avar; Seyed Mohammad Mahdi Mortazavi, Saeid Ahmadjo, Gholam Hossein Zohuri
      Abstract: Bulk homopolymerization and copolymerization of 1-hexene (H) with polar monomers including butyl acrylate (B) and methyl methacrylate (M) in the presence of 1,4-bis (2,6-diisopropylphenyl) acenaphthene diimine nickel (II) dibromide catalyst were investigated. Two cocatalysts, including diethyl aluminium chloride (DEAC) and ethyl aluminium sesqui chloride (EASC), were used to activate the catalyst at ambient temperature. In both the homopolymerization and copolymerization of 1-hexene with polar monomers, the catalyst activity resulted from EASC as cocatalyst was higher than that resulted from DEAC. 1HNMR analysis was used in order to determine incorporation level of polar monomers and branching density of the synthesized polymers. A highest incorporation level of 13.3% mol was obtained using monomer B in the presence of the cocatalyst EASC. In addition, the influence of polar monomers on molecular weight and molecular weight distribution (PDI) was studied for both the homo- and co-polymerizations of 1-hexene in the presence of various cocatalysts. A higher molecular weight and narrower PDI were obtained by using the DEAC cocatalyst compared to the EASC cocatalyst. Glass transition temperature (Tg) and melting point (Tm) of the synthesized polymers were found to be dependent on the cocatalyst type and comonomer incorporation level. The addition of dichloromethane solvent into reaction medium showed a positive effect on comonomer incorporation which could not be seen in bulk polymerization. However, the presence of dichloromethane led to decrease the catalyst activity and molecular weight of the polymers.Homopolymerization and copolymerization of 1-hexene with polar monomers (acrylate type) were carried out using late transition metal catalyst and different cocatalyst.
      PubDate: 2018-01-11T02:45:54.789644-05:
      DOI: 10.1002/aoc.4238
       
  • Nickel(II) and copper(II) complexes of 2,2’-bibenzo[d]thiazole:
           Synthesis, characterisation and biological studies
    • Authors: Omaka N. Omaka; Anthony C. Ekennia, Nwaji N. Njoku, Damian C. Onwudiwe
      Abstract: Benzothiazole moiety has gained a lot of attention because of its importance as essential pharmacophore in the development of metal based drugs. Nickel(II) and copper(II) complexes of a benzothiazole based ligand, 2,2’-bibenzo[d]thiazole (L1), synthesized by the reaction of benzothiazole-2-carbonylchloride and o-aminothiophenol, is reported. The compounds were characterised by elemental and percentage metal analyses, spectroscopic (FTIR and UV–vis), 1H and 13C NMR, Mass spectra, thermal, magnetic moment and molar conductance analyses. The mass spectra, elemental and percentage metal composition of the metal complexes gave a 2:1 ligand to metal stoichiometric mole ratio. The spectral data showed that the ligand was coordinated to the metal ions through the nitrogen atoms of the benzothiazole moiety. The electronic spectra and magnetic susceptibility measurements showed that the nickel and copper complexes adopted square planar geometries. The ligand and its metal(II) complexes were screened against some drug resistant microbes and were found to exhibit varied degree of antimicrobial activities. The nickel complex was more active compared to ciprofloxacin against Staphylococcus aureus and Bacillus cereus. Similarly, the antioxidant potential of the ligand was evaluated. The ligand is a better ferrous ion chelating agent compared to 1,10-phenanthroline and 2,2-bipyridine. The ligand and its complexes exhibited good antimicrobial and Fe2+ chelating properties making them probable compounds of interest in antibiotic and antioxidant drug researches.Novel benzothiazole based ligand, 2,2'-bibenzo[d]thiazole (L1) and its nickel and copper complexes were reported.The compounds exhibited good antimicrobial activity; however, the nickel complex was more active compared to ciprofloxacin against Staphylococcus aureus and Bacillus cereus.The ligand exhibited better ferrous ion chelating agent compared to componds of similar structural characteristics like 1,10-phenanthroline and 2,2-bipyridine.
      PubDate: 2018-01-11T02:45:30.949891-05:
      DOI: 10.1002/aoc.4241
       
  • Biological contour, molecular docking and antiproliferative studies of DNA
           targeted histidine based transition metal(II) complexes: Invention and its
           depiction
    • Authors: Alagarraj Arunadevi; Natarajan Raman
      Abstract: A novel series of histidine derived transition metal complexes were synthesized and characterized by multispectral techniques such as UV-Vis., FT IR, EPR, NMR, ESI-mass analysis and other physico-chemical methods like elemental analysis, molar conductivity, magnetic susceptibility. The synthesized compounds were attempted for their biological prospective. The biological studies involved are DNA interaction (binding and damage), antimicrobial, antioxidant, antiproliferative and molecular docking. DNA interaction studies were carried out with the help of UV-Vis absorption titration, viscosity measurement and cyclic voltammetric techniques which revealed that the synthesized compounds could interact with CT-DNA through intercalative binding mode. A gel electrophoresis assay demonstrated the ability of complexes to cleave the supercoiled pUC18 DNA. The antioxidant property shows that the metal complexes have preferable ability to scavenge hydroxyl radical than the ligand. Moreover, the antimicrobial assay indicates that these complexes are good antimicrobial agents against various pathogens. Furthermore, the in vitro antiproliferative activities of the complexes were examined on HeLa, Hep G2 and NIH 3 T3 cell lines using an MTT assay. The morphological changes were investigated using Hoechst 33258 staining apoptosis assay. In addition, molecular docking studies were executed to considerate the nature of binding of the synthesized complexes with protein and DNA.A novel series of histidine derived transition metal complexes were synthesized and characterized by various spectral techniques. The synthesized complexes are having good intercalative binding ability. They show good antimicrobial and potential antioxidant activities. Moreover, they are found to have superior antiproliferative activity against human cancer cell lines such as HeLa and Hep G2.
      PubDate: 2018-01-11T02:42:45.206972-05:
      DOI: 10.1002/aoc.4250
       
  • The reduction of 4-nitrophenol and 2-nitroaniline by palladium catalyst
           based on a KCC-1/IL in aqueous solution
    • Authors: Sakineh Esfandiari Baghbamidi; Asadollah Hassankhani, Esmael Sanchooli, Seyed Mohsen Sadeghzadeh
      Abstract: KCC-1/IL/Pd NPs can used as an excellent support for the synthesis of highly sparse homogeneous catalyst. KCC-1 has high surface area that was functionalized with ionic liquid phase acting as the strong performers so that the Pd catalyst was well-dispersed without aggregation on the framework of the KCC-1/IL. This nano catalyst was specified by TGA, XRD, TEM, SEM, FT-IR, and ICP. For reduction of 2-nitroaniline and 4-nitrophenol used from the KCC-1/IL/Pd NPs as a green catalyst that showed excellent catalytic activities. Compared with the traditional substrate, KCC-1 substantially increases protection and the accessibility of the nanoparticle sites due to its three dimensional hierarchical structure.KCC-1/IL/Pd NPs can used as a excellent support for the synthesis of highly sparse homogeneous catalyst. This nano catalyst was specified by TGA, XRD, TEM, SEM, FT-IR, and ICP. For reduction of 2-nitroaniline and 4-nitrophenol used from the KCC-1/IL/Pd NPs as a green catalyst that showed excellent catalytic activities. Compared with the traditional substrate, KCC-1 substantially increases protection and the accessibility of the nanoparticle sites due to its three dimensional hierarchical structure.
      PubDate: 2018-01-11T02:41:11.535621-05:
      DOI: 10.1002/aoc.4251
       
  • Kryptofix 5 as an inexpensive and efficient ligand for the
           palladium-catalyzed Mizoroki-Heck reaction
    • Authors: Barahman Movassagh; Shabnam Ranjbari
      Abstract: A novel complex of PdCl2 with a multidentate cryptand ligand, Kryptofix 5, has been prepared and characterized by various techniques including 1H- and 13C NMR spectroscopy, Fourier transform infrared (FT-IR), Raman, ultraviolet and visible (UV-VIS) spectroscopy, inductively coupled plasma (ICP), CHN elemental and energy dispersive X-ray analysis (EDX). This heat- and air-stable complex was utilized as a highly active catalyst for the Mizoroki-Heck reaction of aryl halides with various olefins. Interestingly, it was found that aryl bromides as well as aryl iodides were efficiently cross-coupled with terminal alkenes at 130 °C in 10 min. Furthermore, the least reactive aryl chlorides reacted with styrene to obtain the desired products in acceptable yields.A novel complex of PdCl2 with a multidentate cryptand ligand, Kryptofix 5, has been prepared and characterized by various techniques including 1H- and 13C NMR spectroscopy, Fourier transform infrared (FT-IR), Raman, ultraviolet and visible (UV-VIS) spectroscopy, inductively coupled plasma (ICP), CHN elemental and energy dispersive X-ray analysis (EDX). This heat- and air-stable complex was utilized as a highly active catalyst for the Mizoroki-Heck reaction of aryl halides with various olefins. Interestingly, it was found that aryl bromides as well as aryl iodides were efficiently cross-coupled with terminal alkenes at 130 °C in 10 min. Furthermore, the least reactive aryl chlorides reacted with styrene to obtain the desired products in acceptable yields.
      PubDate: 2018-01-11T02:40:37.869187-05:
      DOI: 10.1002/aoc.4224
       
  • Fe3O4@Propylsilane@Histidine[HSO4-] magnetic nanocatalysts: Synthesis,
           characterization and catalytic application for highly efficient synthesis
           of xanthene derivatives
    • Authors: Seyyedeh Masoumeh Mousavifar; Hassan Kefayati, Shahab Shariati
      Abstract: The surface of Fe3O4 magnetic nanoparticles (MNPs) was modified by chloropropylsilane and histidine. The imidazole group of prepared Fe3O4@Propylsilane@Histidine MNPs converted to imidazolium hydrogen sulfate group and Fe3O4@Propylsilane@Histidine [HSO4-] as a novel environmentally friendly ionic liquid/ magnetite nanoparticle was prepared, successfully. FT-IR, XRD, SEM and TEM instruments was used to identifiy the histidine ionic liquids/magnetite nanoparticles (HILMNPs). The catalytic activity of synthesized HILMNPs was appraised for the synthesis of 9-aryl-1,8-dioxooctahydroxanthene and spiro[indoline-3,9′-xanthene]trione derivatives. The activity of HILMNPs was much better than the other reported heterogeneous and homogeneous catalysts. Furthermore, the prepared catalyst could be separated from the reaction mixture and reused four times without any significant loss in its activity.Fe3O4 was functionalized with chloropropylsilane and histidine and Fe3O4@Propylsilane@Histidine [HSO4-] as a novel solid acid magnetic nanocatalyst was prepared and its performance for the synthesis of 1,8-dioxooctahydroxanthene and some novel spiro[indoline-3,9′-xanthene]triones was investigated.
      PubDate: 2018-01-11T02:36:14.319316-05:
      DOI: 10.1002/aoc.4242
       
  • Silver nanoparticles supported on ionic-tagged magnetic hydroxyapatite as
           a highly efficient and reusable nanocatalyst for hydrogenation of
           nitroarenes in water
    • Authors: Mokhtar Pashaei; Ebrahim Mehdipour
      Abstract: A novel chemically modified magnetic hydroxyapatite (MHAp) was prepared and used as support and stabilizer for the synthesis of silver nanoparticles. First, 1,4-diazabicyclo[2.2.2]octane (DABCO) was successfully grafted onto the surface of MHAp, and then silver nanoparticles were homogeneously loaded on mesoporous MHAp-DABCO (ionic-tagged MHAp) nanocomposite by in situ chemical reduction of silver nitrate using sodium borohydride. The structure and properties of the resulting MHAp-DABCO-Ag nanocomposite were confirmed using various techniques. The catalytic activity of ionic-tagged MHAp-Ag nanocatalyst was investigated for the hydrogenation reaction of nitroarenes in aqueous media. The results reveal that the Ag-containing inorganic–organic nanocomposite is highly efficient for the reduction of a wide range of aromatic nitro compounds under green conditions. The superparamagnetic nature of the nanocatalyst leads to its being readily removed from solution via application of a magnetic field, and it can be easily stored and reused.A highly efficient heterogenized silver nanocatalyst was synthesized on ionic-tagged magnetic hydroxyapatite and was used as an organometallic catalyst for hydrogenation of nitroarenes in water.
      PubDate: 2018-01-11T02:30:56.267027-05:
      DOI: 10.1002/aoc.4226
       
  • Surface modified SPIONs-Cr(VI) ions-immobilized organic-inorganic hybrid
           as a magnetically recyclable nanocatalyst for rapid synthesis of
           polyhydroquinolines under solvent-free conditions at room temperature
    • Authors: Ali Maleki; Negar Hamidi, Saied Maleki, Jamal Rahimi
      Abstract: In this work, a magnetic hybrid dichromate nanocomposite with triphenylphosphine surface modified superparamagnetic iron oxide nanoparticles (SPIONs) as a recyclable nanocatalyst was designed, prepared and characterized by Fourier transform infrared spectroscopy (FT-IR) spectra, X-ray diffraction (XRD) pattern analysis, vibrating sample magnetometer (VSM) curves, X-ray fluorescence (XRF) analysis, thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images and dynamic light scattering (DLS) analysis. Then, it was used in a green and efficient procedure for one-pot multicomponent synthesis of polyhydroquinoline derivatives by the condensation of aldehydes, dimedone or 1,3-cyclohexadione, ethyl acetoacetate and ammonium acetate. This protocol includes some new and exceptional advantages such as short reaction times, low catalyst loading, high yields, solvent-free and room temperature conditions, easy separation and reusability of the catalyst.A recoverable heterogeneous superparamagnetic nanocomposite was prepared, characterized and efficiently examined in an important one-pot multicomponent reaction for the catalytic synthesis of chemically and biologically important polyhydroquinoline derivatives.
      PubDate: 2018-01-11T02:28:57.013889-05:
      DOI: 10.1002/aoc.4245
       
  • Palladium(II) Immobilized Onto the Glucose Functionalized Magnetic
           Nanoparticle as a New and Efficient Catalyst for the One-pot Synthesis of
           Benzoxazoles
    • Authors: Firouz Matloubi Moghaddam; Vahid Saberi, Sepideh Kalhor, Nazila Veisi
      Abstract: Palladium(II) have been immobilized into the nano magnetic Fe3O4 which was functionalized with glucose in order to achieve a one-pot synthesis of 2-substituted benzoxazole derivatives with high yields in the diverse range of organic solvents. The nano catalyst is highly dispersive in polar solvents and can be easily recovered and reused for 6 runs without significant loss of its activity. Finally, the catalyst was fully characterized by FT-IR, TGA, CHN, SEM, EDX and atomic absorption spectroscopy.A catalyst based on Pd immobilized onto glucose functionalized magnetic nanoparticles is synthesized for the benzoxazoles synthesis.The catalyst recovery is carried out by applying an external magnetic field.Using glucose as a green ligand for synthesis of benzoxazole derivatives.
      PubDate: 2018-01-11T02:26:03.374825-05:
      DOI: 10.1002/aoc.4240
       
  • Polypyrrole/Fe3O4/CNT as a recyclable and highly efficient catalyst for
           one-pot three-component synthesis of pyran derivatives
    • Authors: Seyedeh Fatemeh Hojati; Amirhassan Amiri, Nasrin MoeiniEghbali, Sakineh Mohamadi
      Abstract: Polypyrrole (PPY)/Fe3O4/CNT has been synthesized and characterized by FT-IR, TEM and SEM techniques and its catalytic activity has been evaluated in the synthesis of several series of pyran derivatives. Tetrahydrobenzo[b]pyranes, 4H-pyran-3-carboxylates, 4H,5H-pyrano[3,2-c]chromenes and dihydropyrano[2,3-c]pyrazoles have been successfully prepared from one-pot three-component condensation of aldehyde, malononitrile and active methylene-containing compounds (dimedone /ethyl acetoacetate/4-hydroxycoumarin/3-methyl-2-pyrazoline-5-one) using PPY/Fe3O4/CNT as a new and reusable heterogeneous catalyst. The present method offer several advantages such as; high yields of products, short reaction times, easy work-up procedure and easy separation of the catalyst from the reaction mixture due to its magnetic character. Furthermore, chemoselective synthesis of bis-benzo[b]pyran from terephthalaldehyde can be achieved by this method.PPY/Fe3O4/CNT has been synthesized, characterized and its catalytic activity has been evaluated in the synthesis of several series of pyran derivatives via multi-component reaction.
      PubDate: 2018-01-11T02:25:36.454328-05:
      DOI: 10.1002/aoc.4235
       
  • Catalytic activity of nickel(II), copper(II) and
           oxovanadium(II)-dihydroindolone complexes towards homogeneous oxidation
           reactions
    • Authors: Mohamed Shaker S. Adam
      Abstract: Three novel paramagnetic metal complexes (MH2ID) of Ni2+, Cu2+ and VO2+ ions with 3-hydroxy-3,3’-biindoline-2,2’-dione (dihydroindolone, H4ID) were synthesized and characterized by different spectroscopic methods. The ligand (H4ID) was synthesized via homocoupling reaction of isatin in presence of phenylalanine in methanol. Complexation of low valent Ni2+, Cu2+ ions and high valent VO2+ ions with H4ID carried out in 1: 2 molar ratios. A comparison in the catalytic potential of paramagnetic complexes of low and high valent metal ion was explored in the oxidation processes of cis-cyclooctene, benzyl alcohol and thiophene by an aqueous H2O2, as a green terminal oxidant, in the presence and absence of acetonitrile, as an organic solvent, at 85 °C. NiH2ID, CuH2ID and VOH2ID show good catalytic activity, i.e. good chemo- and regioselectivity. VOH2ID has the highest catalytic potential compared to both Ni2+- and Cu2+-species in the same homogenous aerobic atmosphere. Catalytic oxidation of other alkenes and alcohols was also studied using NiH2ID, CuH2ID or VOH2ID as a pre-catalyst by an aqueous H2O2. A mechanistic pathway for those oxidation processes was proposed.Three novel complexes of Ni2+, Cu2+ and VO2+ ions with dihydroindolone were synthesized and characterized. The catalytic efficiency of Ni-, Cu- and VO-complex was measured in the redox processes of cis-cyclooctene, benzyl alcohol and thiophene by an aqueous H2O2 in acetonitrile or under solvent-free conditions. VO-complex is more effective catalyst than Ni- and Cu-complexes. The more Lewis acid character and the high oxidation number of the V4+/V5+ ions could be the main reasons for that higher catalytic potential. Under solvent-free conditions, the catalytic processes are less sufficient compared to that in acetonitrile with all complex catalysts. The catalytic potential of Ni-, Cu- and VO-complexes was investigated in redox processes of various aliphatic or cyclic alkenes and alcohols. A short mechanistic pathway of the catalytic redox process is presented involving electron and oxygen transfers.
      PubDate: 2018-01-11T02:24:45.403963-05:
      DOI: 10.1002/aoc.4234
       
  • Preparation, crystal structure, spectroscopic studies, DFT calculations,
           antibacterial activities and molecular docking of a tridentate Schiff base
           ligand and its cis-MoO2 complex
    • Authors: S. Yousef Ebrahimipour; Mehrji Khosravan, Jonathan White, Sahar Fekri
      Abstract: We synthesized a tridentate Schiff base ligand, 6-(((2-hydroxyphenyl)amino)methylene)-2-methoxycyclohexa-2,4-dienone [H2L], as well as its Mo(VI) complex [MoO2(L)(DMSO)], and then characterized them completely using elemental analysis, FT-IR, UV–Vis and 1HNMR spectroscopy techniques. X-ray single crystal diffraction method was used for the determination of the structure of the synthesized ligand and complex. All other spectroscopic techniques performed, confirmed that [MoO2(L)(DMSO)]had an octahedral geometry around the Mo(VI) central ion coordinated by the donor atoms of the deprotonated ligand, two oxido groups and one oxygen atom of DMSO molecule. Hybrid functional B3LYP with DGDZVP as basis set was applied for DFT calculations of the compounds in their ground state. The MEP, Mulliken, HOMO-LUMO energy gap and thermodynamic properties of the compounds were also theoretically predicted. In-vitro antimicrobial studies on the synthesized compounds indicated the great antibacterial activities of the Mo(VI) complex against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus bacteria.– A tridentate Schiff base ligand and its cis-MoO2 complex were synthesized and fully characterized.– The antimicrobial activity of the synthesized compounds were also investigated.– The MEP, HOMO-LUMO energy gap and thermodynamic properties were predicted using hybrid functional B3LYP with DGDZVP as basis set.
      PubDate: 2018-01-11T02:21:14.385349-05:
      DOI: 10.1002/aoc.4233
       
  • Design, synthesis, pharmacological evaluation and DNA interaction studies
           of binuclear Pt(II) complexes with pyrazolo[1,5-a]pyrimidine scaffold
    • Authors: Miral V. Lunagariya; Khyati P. Thakor, Bhargav N. Waghela, Chadramani Pathak, Mohan N. Patel
      Abstract: Substituted pyrazolo[1,5-a]pyrimidine ligands were synthesized by cyclization, using 3-(thiophen-2-yl)-1H-pyrazol-5-amine with substituted enones (3-phenyl-1-(pyridin-2-yl)prop-2-en-1-one) in presence of KOH and DMF as solvent to form cyclic aromatic compounds. The substituted pyrazolo[1,5-a] pyrimidine based binuclear PtII complexes containing neutral tetradentated ligands have general formula [Pt2(5a–5f)Cl4], (where, (5a -5f) = pyrazolo[1,5-a] pyrimidine ligand). This compounds were characterized by physicochemical and spectroscopic method like elemental analyses, UV-Visible, FT-IR, EDX, TGA, molar conductivity, magnetic susceptibility measurements, mass spectroscopy, 1H and 13C NMR method. The square planar geometry was predicted by electronic spectral study. All PtII compounds were evaluated by antimicrobial assay, in vitro brine shrimp assay, in vivo cellular level bioassay using S. Pombe cells and anti-tuberculosis study. LC50 (50% lethal concentration) values of compounds are observed between 6.450 - 102.07 μg/mL. UV-vis absorption titration, competitive displacement assay, molecular docking and viscosity measurement were carried out to examine the binding type and binding strength of complexes. The binding studies suggest partial intercalative binding mode of the complexes and the observed binding constant (Kb) values are found in the order of 6d > 6b > 6c > 6a > 6e > 6 f. The anti-proliferative cytotoxicity of the synthesized PtII complexes (6a-6f) were tested against the HCT-116 (Human Colorectal Carcinoma) cancer cell line.Synthesis of binuclear PtII complexes with tetradentate heterocyclic pyrazolo[1,5-a]pyrimidine derivatives ligands.Characterization by elemental analysis (C, H, N, S), 1H NMR, 13C NMR, FT-IR, UV–visible, EDX, molar conductivity, magnetic susceptibility measurements, mass spectroscopic and TGA spectroscopy.Accommodation of the binuclear Pt(II) complexes in the DNA base pairs as an partial intercalative mode of binding have been confirmed through molecular docking, absorption titration analysis, viscosity measurements and fluorescence quenching analysis.DNA cleavage assay was carried out by gel electrophoresis technique.All the heterocyclic compounds like, pyrazolo[1,5-a]pyrimidine based ligands, cisplatin, transplatin and their binuclear Pt(II) complexes have been study for in vitro antibacterial assay, cellular level cytotoxicity against S. Pombe cells, antituberculosis, in vitro cytotoxicity against brine shrimp lethality bioassay (LC50) and in vitro anti-proliferation cytotoxicity against HCT-116 cancer cell line (IC50).
      PubDate: 2018-01-11T02:19:09.929363-05:
      DOI: 10.1002/aoc.4222
       
  • Novel synthesis of Fe2O3–Pt ellipsoids coated by double-shelled La2O3 as
           a catalyst for the reduction of 4-nitrophenol
    • Authors: Yan Gao; Jiasheng Fang, Yiwei Zhang, Chao Zhang, Shuo Zhao, Yuming Zhou, Mengqiu Huang, Xiaoli Sheng
      Abstract: A facile strategy is reported for the fabrication of Pt-loaded core–shell nanocomposite ellipsoids (Fe2O3-Pt@DSL) consisting of ellipsoidal Fe2O3 cores, double-layered La2O3 shells and deposited Pt nanoparticles (NPs). The formation of the doubled-shelled structure uses Fe2O3-Pt@mSiO2 as template sacrificial agent and it involves the re-deposition of silica and self-assembly of metal oxide units. The preparation methods of double-shelled metal oxides avoid repeated coating and etching and could be utilized to fabricate other shaped double-shelled composites. Characterization results indicated that the Fe2O3-Pt@DSL nanocomposites possessed mesoporous structure and tunable shell thickness. Moreover, due to the formation of Fe2O3 and La2O3 composites, Pt NPs can also be stabilized via deposition on chemically active oxides with a synergistic effect. Therefore, as a catalyst for the reduction of 4-nitrophenol, Fe2O3-Pt@DSL showed superior catalytic activity and reusability due to structural superiority and enhanced composite synergy. Finally, well-dispersed Pt NPs were encapsulated into the void between the shell layers to construct the Fe2O3-Pt@DSL-Pt catalyst.Synthetic strategy for yolk–shell Fe2O3-Pt@DSL. Novel yolk–shell Fe2O3/La2O3 ellipsoids encapsulating Pt NPs were synthesized using a facile method. A dominating mechanism for the nanocomposites involved re-deposition and self-assembly. The Fe2O3-Pt@DSL catalyst showed high catalytic performance compared with other catalysts.
      PubDate: 2018-01-11T02:17:46.248068-05:
      DOI: 10.1002/aoc.4208
       
  • Stable trans isomer as the kinetic and theromodynamic product for the
           oxidative addition of MeI to cycloplatinated(II) complexes comprising
           isocyanide ligands
    • Authors: Hamid R. Shahsavari; Reza Babadi Aghakhanpour, Mojdeh Hossein-Abadi, Reza Kia, Paul R. Raithby
      Abstract: The present investigation introduces a new series of cycloplatinated(II) complexes, with the general formula Pt(O-bpy)(Me)(CN-R)] (R = benzyl, 2-naphtyl and tert-butyl), which are able to generate the stable trans-Pt(IV) product in the solution after the reaction with iodomethane. In fact, the trans product is both the kinetic and thermodynamic product of the reaction; this observation was supported by DFT calculations. These Pt(II) complexes are supported by 2,2'-bipyridine N-oxide (O-bpy) and one of several isocyanides as the cyclometalated and ancillary ligands, respectively. These new Pt(II) complexes undergo oxidative addition with MeI to give the corresponding trans-Pt(IV) complexes. All the complexes were identified employing the multi-nuclear NMR spectroscopy and single crystal X-ray crystallography. The kinetic investigations were also performed for the oxidative addition reactions in order to measure the reaction rates; the reaction was followed by UV-Vis spectroscopy. The rates obtained follow the trend CN-tBu> CN-Bz> CN-2 Np for the CN-R ligands in the Pt(II) complexes. The order can be related to the degree of electron-donation of the R group (tert-butyl> benzyl> 2-naphtyl).The new Pt(II) complexes bearing various isocyanide ligands underwent of oxidative addition reaction to give the corresponding trans-Pt(IV) complexes. The trans-Pt(IV) isomer was both the kinetic and thermodynamic product of the reaction.
      PubDate: 2018-01-05T04:37:43.228972-05:
      DOI: 10.1002/aoc.4216
       
  • Study of the chemical structure and the microbial effect of iron(III)
           metal ions with four consecutive generations of quinolones in a nanometric
           form for the purpose of increasing the efficacy of antibacterial and
           antifungal drugs
    • Authors: Moamen S. Refat; Mohamed Y. El-Sayed, Reham F. Hassan
      Abstract: A new series of iron(III) complexes with different fourth generation of quinolone drugs of the type [Fe(L)n(Cl)x]⋅yH2O ((1) L: nalidixic acid, n = 3, x = 3, y = 3; (2) L: oxolonic acid, n = 3, x = 3, y = 0; (3) L: pipemidic acid, n = 3, x = 3, y = 2; (4) L: lomefloxacin, n = 3, x = 3, y = 0; (5) L: pefloxacin mesylate, n = 3, x = 3, y = 2; (6) L: levofloxacin, n = 3, x = 3, y = 6) were synthesized and identified using microanalysis, Fourier transform infrared spectroscopy, conductance data, effective magnetic moments and electronic UV–visible spectra. In these six complexes, the quinolone drug chelates act in a unidentate manner via nitrogen atom of pyridone/piperazyl moiety. Electronic spectroscopic data are in agreement with an octahedral geometrical structure. Thermal degradation analyses in nitrogen gas were used to investigate the number and location of water molecules. The thermal decomposition process is completed in 3−5 steps, the first step being responsible for loss of uncoordinated water molecules and the steady state of all complexes occurs at around 500 °C with oxide forms as residual products. The stabilities of iron(III) complexes 1–6 were studied in terms of activation energy E*, entropy ΔS*, enthalpy ΔH* and Gibbs free energy ΔG* that were estimated using Coats–Redfern and Horowitz–Metzger non-isothermal methods. Molecular docking was used to predict the binding between some of the quinolone drugs and the receptor of prostate cancer 2q7k hormone.General structure of four quinolones and four chelation modes towards metal ions.
      PubDate: 2018-01-05T04:31:23.153905-05:
      DOI: 10.1002/aoc.4195
       
  • Synthesis, structure and catalytic polymerization activity of
           half-sandwich cyclometallated iridium complexes
    • Authors: Zi-Jian Yao; Peng Li, Kuan Li, Wei Deng
      Abstract: A series of mononuclear half-sandwich cyclometallated iridium complexes with Schiff base ligands were synthesized in good yields. Five air-stable C,N-chelate mode complexes were obtained smoothly through metal-mediated C─H bond activation. Treatments of dimeric metal complexes [Cp*IrCl2]2 with ligands L1–L5 afforded the corresponding C,N-chelate mononuclear half-sandwich iridium(III) complexes 1–5. These iridium complexes exhibit high catalytic activity for norbornene polymerization. Both steric and electronic effects of the substituted groups have influences on the behaviors of the polymerization process. All complexes were characterized using infrared and NMR spectroscopies and elemental analysis. Molecular structures of complexes 1, 2 and 5 were further confirmed using single-crystal X-ray analysis.A series of mononuclear half-sandwich cyclometallated iridium complexes with Schiff base ligands were synthesized in good yields. These iridium complexes exhibited high catalytic activity for norbornene polymerization.
      PubDate: 2018-01-03T04:40:44.29806-05:0
      DOI: 10.1002/aoc.4239
       
  • Statistical optimization and modeling approach for azo dye decolorization:
           Combined effects of ultrasound waves and nanomaterial-based adsorbent
    • Authors: Jaleh Pooralhossini; Mohammad Ali Zanjanchi, Mehrorang Ghaedi, Arash Asfaram, Mohammad Hossein Ahmadi Azqhandi
      Abstract: This study is devoted to an investigation of the effects of sonication time, adsorbent mass, pH and sunset yellow (SY) and disulfine blue (DB) concentration on the removal of DB and SY from water. Artificial neural network and response surface methodology approaches were used to optimize an analytical model to calculate the DB and SY removal performance of tin oxide nanoparticles loaded on activated carbon. The performance of both models was statistically evaluated in terms of the coefficient of determination (R2), root mean squared error (RMSE), mean absolute error (MAE) and absolute average deviation (AAD), and graphical plots were also used for comparison of the models. The obtained results show that the artificial neural network model outperforms the classical statistical model in terms of R2, RMSE, MAE and AAD for both dyes. Various isotherm models were studied for fitting the experimental equilibrium data, and the results confirm the applicability of the Langmuir isotherm for description of the adsorption equilibrium. Various kinetic models were applied to the experimental data and the results reveal that the pseudo-second-order model with better correlation is superior to the other kinetic models. The significant factors were optimized using the desirability function approach combined with central composite design. The obtained optimal point is located in the valid region and the experimental confirmation indicates good agreement between the predicted optimal points and the experimental data.The effects of sonication time, adsorbent mass, pH and sunset yellow (SY) and disulfine blue (DB) concentration on the removal of DB and SY from water were investigated. Artificial neural network and response surface methodology approaches were used to optimize the analytical model to calculate the DB and SY removal performance of tin oxide nanoparticles loaded on activated carbon.
      PubDate: 2018-01-02T03:36:55.416236-05:
      DOI: 10.1002/aoc.4205
       
  • New designed DNA light switch Ruthenium complexes as DNA photocleavers and
           Topoisomerase I inhibitors
    • Authors: Xue-Wen Liu; Yang Xiao, Wei-Gen Peng, Li-Jin Zhao, You-Ming Shen, Song-Bai Zhang, Ji-Lin Lu
      Abstract: Two ruthenium complexes containing a new ligand phipz (phipz = 2-(1,10-phenanthroline)-1H-imidazo[4,5-b]phenazine) were designed and synthesized. These complexes were found to inhibit the DNA supercoiled relaxation mediated by topoisomerase I (topo I), cleave DNA under irradiation and bind to calf thymus DNA through intercalative mode. Furthermore, complex 2 shows higher photocleavage activity, topo I inhibition activity and DNA affinity than complex 1. Additionally, introduction of phenazine unit may be the reason that two complexes exhibit DNA ‘light switch’ behavior. The present work shows that two complexes might be potential as new DNA ‘light switches’, DNA photocleavers and topo I inhibitors.DNA ‘light switch’ effects of two Ru(II) complexes, [Ru(bpy)2(phipz)]2+ and [Ru(phen)2(phipz]2+, were observed after binding to CT-DNA due to the introduction of phenazine unit. Both complexes can also serve as photocleavers and topo I inhibitors.
      PubDate: 2018-01-02T03:32:19.627284-05:
      DOI: 10.1002/aoc.4231
       
  • Evaluation of UiO-66 metal organic framework as an effective sorbent for
           Curcumin's overdose
    • Authors: Hossein Molavi; Mostafa Zamani, Mozhgan Aghajanzadeh, Hamidreza Kheiri Manjili, Hossein Danafar, Akbar Shojaei
      Abstract: Metal organic frameworks (MOFs) UiO-66 (UiO stands for University of Oslo) and NH2-UiO-66 were prepared and characterized as sorbent (antidotal agents) for curcumin (CUR) adsorption. The structure of products were characterized by X-ray powder diffraction (XRD), Field emission scanning electron microscopy (FESEM), thermogravimetric analysis (TGA), Attenuated Total Reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and N2 adsorption–desorption measurements. FESEM showed NH2-UiO-66 displayed symmetrical crystals with triangular base pyramid morphology, with the particle size around 100 nm and uniform size distribution. Adsorption capacities of CUR/MOFs with different mass ratios in the feed were investigated in the present study, and this investigation revealed that when the CUR/MOFs with mass ratio was around 0.4, the absorption capacity of NH2-UiO-66 had tended to maximum. Although, functionalization reduced the specific surface area and free volume, introducing polar amine groups could improve the affinity of NH2-UiO-66 respect to CUR. Kinetic studies showed that the kinetic data are well fitted with the pseudo- second-order model. MTT assay revealed that MOFs at the concentration range of 0–560 μg/ml had no cytotoxic effect on the Human Foreskin Fibroblast normal cell line (HFF-2). These results suggest that these MOFs could be safe as sorbent for adsorb CUR from the body.Metal organic framework (MOFs) UiO-66 (UiO stands for University of Oslo) and factionalized NH2-UiO-66 were prepared and characterized as antidotal agents (adsorbent) for curcumin (CUR) adsorption. The structure of MOFs was confirmed by Fourier transform infrared (ATFT-IR), Field emission scanning electron microscopy (FESEM) and X-ray diffraction (XRD). Thermal behavior of MOFs was investigated using with thermogravimetric analyzer (TGA) in nitrogen atmosphere to check the thermal stability.
      PubDate: 2018-01-02T03:32:10.249294-05:
      DOI: 10.1002/aoc.4221
       
  • Anti-neurotoxic evaluation of synthetic and characterized metal complexes
           of thiosemicarbazone derivatives
    • Authors: Fathy A. El-Saied; Tarek A. Salem, Mohamad M.E. Shakdofa, Ahmed N. Al-Hakimi
      Abstract: Quinoline-2-caboxyaldehyde thiosemicarbazone (HL1) and quinoline -2-caboxyaldehyde N-dimethyl thiosemicarbazone (HL2) metal complexes were prepared and characterized using analytical and spectroscopic techniques. The measurements showed that ligands behave as monovalent or neutral tridentate ligands bonding via azomethine, quinoline ring nitrogen atoms and sulfur atoms in thiol or thion forms. The anti-neurotoxic effect of ligands and their complexes showed that, exposure to aluminum increase oxidative stress in the brain, an effect that could be offset by concomitant thiosemicarbazone complexes. Complexes could be having an effect on absorption or excretion of aluminum, due to their chelating activity. These findings may shed light on the potential clinical importance of thiosemicarbazone complexes in Alzheimer's disease.Anti-oxidative and chelating activity of quinoline-2-caboxyaldehyde thiosemicarbazone (HL1) and quinoline -2-caboxyaldehyde N-dimethyl thiosemicarbazone (HL2)
      PubDate: 2018-01-02T03:25:26.020003-05:
      DOI: 10.1002/aoc.4215
       
  • Fe3O4/MIL-101(Fe) nanocomposite as an efficient and recyclable catalyst
           for Strecker reaction
    • Authors: Mohammad Mahdi Mostafavi; Farnaz Movahedi
      Abstract: A highly porous metal-organic framework, MIL-101(Fe), was prepared by a solvothermal method in the presence of amino-modified Fe3O4@SiO2 nanoparticles, in order to achieve Fe3O4/MIL-101(Fe) nanocomposite, which was characterized by XRD, FT-IR, SEM, TEM, BET, and VSM. This hybrid magnetic nanocomposite was employed as heterogeneous catalyst for α-amino nitriles synthesis through three-component condensation reaction of aldehydes (ketones), amines, and trimethylsilyl cyanide in EtOH, at room temperature. The recoverability and reusability was admitted for the heterogeneous magnetic catalyst; no significant reduction of catalytic activity was observed even after five consecutive reaction cycles.A highly porous metal-organic framework, MIL-101(Fe), was prepared by a solvothermal method in the presence of amino-modified Fe3O4@SiO2 nanoparticles, in order to achieve Fe3O4/MIL-101(Fe) nanocomposite. This hybrid magnetic nanocomposite was employed as heterogeneous catalyst for α-amino nitriles synthesis through three-component condensation reaction of aldehydes (ketones), amines, and trimethylsilyl cyanide in EtOH, at room temperature. The recoverability and reusability was admitted for the heterogeneous magnetic catalyst; no significant reduction of catalytic activity was observed even after five consecutive reaction cycles.
      PubDate: 2018-01-02T03:22:39.114075-05:
      DOI: 10.1002/aoc.4217
       
  • Design and synthesis of a magnetic hierarchical porous organic polymer: A
           new platform in heterogeneous phase-transfer catalysis
    • Authors: Arash Mouradzadegun; Mohammad Reza Ganjali, Mahsa Alsadat Mostafavi
      Abstract: Recyclable phase transfer catalysts containing magnetic nanoparticles (MNPs) have been known as a major trend towards sustainable catalysts. In this study, a novel class of magnetic porous polymer on the basis of calix[4]resorcinarene was synthesized starting from silica-coated Fe3O4 core-shell nanoparticles. This compound was found as an efficient phase transfer catalyst to the conversion of benzyl halides into benzyl azides and cyanides in good yields. The catalyst could be used at least for five consecutive cycles without appreciable loss in the catalytic activity.A new synthesized magnetic porous polymer on the basis of calix[4]resorcinarene provides a heterogeneous catalytic system for the synthesis of benzyl cyanides and benzyl azides starting from benzyl halides.
      PubDate: 2018-01-02T03:20:46.329494-05:
      DOI: 10.1002/aoc.4214
       
  • Polymer complexes. LXIX. Some divalent metal(II) polymer complexes of
           potentially bidentate monomer
           N-[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenyl]-acrylamide: Synthesis,
           spectroscopic characterization, thermal properties, antimicrobial agents
           and DNA studies
    • Authors: A.Z. El-Sonbati; M.A. Diab, Sh.M. Morgan, A.M. Eldesoky, M.Z. Balboula
      Abstract: Monomer of N-[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenyl]-acrylamide (HL) and some transition metal polymeric complexes of the general formula {[M(HL)(OH2)2(OCOCH3)2] xH2O}n (M = Co(II), x = 2; Ni(II), x = 3; Mn(II), x = 2) and [Cd(HL)2(OCOCH3)2] were synthesized and characterized by elemental analysis, IR, UV spectroscopy, conductance measurements, magnetic susceptibility, thermogravimetric analyses and X-ray diffraction analysis. In all polymer complexes, the spectral data revealed that the ligand act as bidentate neutral molecule and coordinate to metal ion through enolic sulphonamide OH and isoxazol-N. In all polymer complexes, the spectral data revealed that the ligand act as bidentate neutral molecule and coordinate to metal ion through enolic sulphonamide OH and isoxazol-N. The molar conductance data revealed that the polymer complexes are non-electrolytes while UV-vis and magnetic measurements data have been shown that the polymer complexes have octahedral geometry. All the studies revealed coordination six for the metals in all the polymer complexes and octahedral structures were suggested. The inhibitive effect of HL against C38 steel was investigated in 2 M HCl solution (tafel polarization, electrochemical impedance spectroscopy (EIS) and electrochemical frequency modulation (EFM) methods). The type of HL is mixed inhibitor whose adsorption habit onto C38 steel.The advantages of electrochemical frequency modulation (EFM) test give it an ideal for online monitoring of corrosion. The data of EFM in acidic solution with and without various doses of N-[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenyl]-acrylamide (HL) monomer is discussed. The EFM experimental data were utilized two unlike models: diffusion complete control of the cathodic reaction and the “activation” model. The higher peaks were utilized to measure the (icorr), (CF-2 and CF-3) and (βc and βa). The EFM parameters show that, the appended of HL at a given dose to the acidic solution lower the current corrosion density, lead to these compounds protect the corrosion of alloy through adsorption. The best data of CF-2 and CF-3 are similar to their theoretical data of 2.0 and 3.0, respectively lead to the calculated value are quality good.
      PubDate: 2018-01-02T03:16:31.873509-05:
      DOI: 10.1002/aoc.4207
       
  • Gold nanoparticles supported on thiol-functionalized reduced graphene
           oxide as effective recyclable catalyst for synthesis of
           tetrahydro-4H-chromenes in aqueous media
    • Authors: Hossein Naeimi; Maryam Farahnak Zarabi
      Abstract: Gold nanoparticles supported on thiol-functionalized reduced graphene oxide (AuNPs@RGO-SH) were found to be a biocompatible, stable, recyclable heterogeneous catalyst. The catalysts were characterized by field emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), and X-ray diffraction spectroscopy (XRD). The obtained catalyst was used in synthesis of tetrahydro-4H-chromenes in aqueous media with excellent yields. The catalysts could be easily separated from the reaction mixture and recovered several times without a significant loss of activity.Gold nanoparticles supported on thiol-functionalized reduced graphene oxide (AuNPs@RGO-SH) used as highly efficient and reusable catalysts for the preparation of tetrahydro-4H-chromenes.
      PubDate: 2018-01-02T03:11:12.016521-05:
      DOI: 10.1002/aoc.4225
       
  • Preparation of high-activity AgBr/Ag3PO4 photocatalyst based on
           hexadecyltrimethylammonium bromide and mechanism of photocatalytic
           enhancement
    • Authors: Limin Song; Tongtong Li, Shujuan Zhang
      Abstract: A high-activity AgBr/Ag3PO4 heterojunction photocatalyst was synthesized based on hexadecyltrimethylammonium bromide. Its microspheres were characterized using X-ray diffractometry, transmission electron microscopy and ultraviolet–visible diffuse reflectance spectroscopy. The new photocatalyst with high photocatalytic activity exceptionally outperforms pure Ag3PO4 and AgBr in methyl orange degradation. The enhancement of photocatalytic activity is attributed to the efficient separation of electron–hole pairs. In this photocatalytic reaction, h+ and •O2− are the main reactive species that induce visible-light-driven degradation.A high-activity AgBr/Ag3PO4 heterojunction photocatalyst was synthesized. The new photocatalyst with high photocatalytic activity outperforms pure Ag3PO4 and AgBr in methyl orange degradation. The enhancement of photocatalytic activity is attributed to the efficient separation of electron–hole pairs. The •OH species formed in the photocatalytic reaction may be the main reactive oxygen species that induce visible-light-driven degradation.
      PubDate: 2018-01-02T03:05:51.31937-05:0
      DOI: 10.1002/aoc.4209
       
  • Methanol aided synthesis of PdNPs decorated on montmorillonite K 10 and
           its implication in Suzuki Miyaura type cross coupling reaction under base
           free condition
    • Authors: Abhijit Mahanta; Prasanta Kumar Raul, Sanjib Saikia, Utpal Bora, Ashim Jyoti Thakur
      Abstract: An efficient catalyst PdNPs decorated on Montmorillonite K 10 is prepared by simply stirring Pd(OAc)2 in methanol at room temperature without using any external reducing agent. The catalyst shows excellent activity for Suzuki Miyaura type cross coupling reaction between aryl diazonium salt and arylboronic acid under ligand and base free reaction conditions within short reaction time. The main advantage of this methodology is the easy synthesis of heterogeneous PdNPs @ Mont K 10 catalyst in a mild condition without using any reducing agent or additive and the catalyst is very efficient for biaryl synthesis. The catalyst is well characterized by SEM, EDX, TEM, BET, Powder XRD, TGA, DSC etc. The reaction pathway is greener with aqueous reaction medium, base free reaction condition, room temperature and reusable heterogeneous catalyst.The work describes an efficient method for Suzuki-Miyaura type cross coupling reaction between aryl diazonium salt and arylboronic acid catalyzed by a prepared catalyst Pd@K 10. The catalyst is prepared by simply stirring Pd(OAc)2/Mont K 10 in methanol at room temperature without using any reducing agent. The catalyst is found to be reusable and it is characterized by different characterization techniques.
      PubDate: 2017-12-29T03:26:13.144634-05:
      DOI: 10.1002/aoc.4192
       
  • Synthesis, spectroscopic, thermal analyses, biological activity and
           molecular docking studies on mixed ligand complexes derived from Schiff
           base ligands and 2,6-pyridine dicarboxylic acid
    • Authors: Hanan F. Abd El-Halim; Gehad G. Mohamed
      Abstract: Two novel Schiff base ligands (La and Lb) were prepared from the condensation of quinoline 2-aldehyde with 2-aminopyridine (ligand La) and from the condensation of oxamide with furfural (ligand Lb). Mixed ligand complexes of the type M+2La/b Lc were prepared, where (La and Lb) the primary ligands and Lc was 2,6-pyridinedicarboxylic acid as secondary ligand. Metal ions used were Fe(II), Co(II), Ni(II) and Zn(II) for mixed ligands La Lc and Fe(II), Co(II), Ni(II), Cu(II), Hg(II) and Zn(II) for LbLc mixed ligands. La and Lb Schiff base ligands were both characterized using elemental analyses, molar conductance, IR, 1H and 13C NMR. Mass spectra for Lb, [Zn(La)LcCl]Cl and [Cu(Lb)LcCl]Cl were also studied. ESR spectrum of the [Cu(Lb) LcCl]Cl complex was also recorded The metal complexes were synthesized and characterized using elemental analyses, spectroscopic (IR, 1H NMR, UV-visible, diffused reflectance), molar conductance, magnetic moment and thermal studies. The IR and 1H NMR spectral data revealed that 2,6-pyridinedicarboxalic acid ligand coordinated to the metal ions via pyridyl N and carboxylate O without proton displacement. In addition, the IR data showed that La and Lb ligands behaved as neutral bidentate ligands with N2 donation sites (quinoline N and azomethine N for La and two azomethine N for Lb). Based on spectroscopic studies, an octahedral geometry was proposed for the complexes. The thermal stability and degradation of the metal complexes were investigated by thermogravimetric analysis. The binding modes and affinities of La, Lb and Zn(II) complexes towards receptors of crystal structure of E. coli (PDB ID: 3 t88) and mutant oxidoreductase of breast cancer (PDB ID: 3 hb5) receptors were also studied.The antimicrobial activity against two species of Gram positive, Gram negative bacteria and fungi were tested for the Schiff base ligands, 2,6-pyridinedicarboxylic acid and the mixed ligand complexes and revealed that the synthesized mixed ligand complexes exhibited higher antimicrobial activity than their free Schiff base ligands.Antimicrobial activity of La, Lb and their mixed ligand complexes.
      PubDate: 2017-12-27T01:45:56.48976-05:0
      DOI: 10.1002/aoc.4176
       
  • Synthesis of gold nanoparticles decorated on sulfonated three-dimensional
           graphene nanocomposite and application as a highly efficient and
           recyclable heterogeneous catalyst for Ullmann homocoupling of aryl iodides
           and reduction of p-nitrophenol
    • Authors: Minoo Dabiri; Seyede Razie Banifatemi Kashi, Noushin Farajinia Lehi, Sahareh Bashiribod
      Abstract: Gold nanoparticles were decorated onto sulfonated three-dimensional graphene (3DG-SO3H) through spontaneous chemical reduction of HAuCl4 by 3DG-SO3H. This nanocomposite exhibited excellent catalytic activity for the synthesis of symmetric biaryls via the Ullmann homocoupling of aryl iodides in an aqueous medium. Additionally, this nanocomposite was used as a catalyst for the reduction of p-nitrophenol to p-aminophenol. The catalyst could be used more than six times successively without significant deactivation.Gold nanoparticles were decorated over sulfonated three-dimensional graphene (3DG-SO3H) through spontaneous chemical reduction of HAuCl4 by 3DG-SO3H. The Ullmann homocoupling of aryl iodides and reduction of 4-nitrophenol were successfully accomplished.
      PubDate: 2017-12-22T04:57:53.89723-05:0
      DOI: 10.1002/aoc.4189
       
  • Synthesis, characterization, DNA binding, apoptosis and molecular docking
           of three Mn(II), Zn(II) and Cu(II) complexes with terpyridine-based
           carboxylic acid
    • Authors: En-Jun Gao; Yun-Hui Feng, Jun-Qi Su, Bo Meng, Bing Jia, Zhen-Zhen Qi, Ting-Ting Peng, Ming-Chang Zhu
      Abstract: A series of novel cytotoxic compounds, [Mn(cpt)2], [Zn(tpt)(H2O)2]⋅DMA⋅2(H2O) and [Cu(tpt)]⋅DMA (cpt = 4′-(4-carboxyphenyl)-2,2′:6′,2″-terpyridine, tpt = 4-(2,4,6-tricarboxylphenyl)-2,2′:6′,2″-terpyridine, DMA = (CH3)2NH), were isolated and characterized. The structures of these complexes were characterized using single-crystal X-ray diffraction. The mode and extent of binding between fish sperm DNA and the complexes were investigated using fluorescence spectroscopy and molecular docking. These results indicate the ability of the complexes to bind to DNA with different binding affinities. The binding of the Zn(II) complex with DNA is stronger than that of the corresponding Cu(II) analogue, which is expected due to the z* effect and geometry. The ability of these complexes to cleave pBR322 plasmid DNA was demonstrated using gel electrophoresis assay, showing that the complexes have effective DNA cleavage activity. In addition, the cytotoxic effects of these complexes were examined on HeLa cells (human cervix epithelia carcinoma cells) in vitro. The three complexes exhibit different cytotoxic effects and decent cancer cell inhibitory rate. This means that the structures and type of metal have a great influence on the activity of these novel complexes.The major chemical and biological findings of this study have demonstrated that the complexes can indeed show activity against human cancer cells in vitro in a reasonable range of concentrations, which indicates that these complexes are very promising candidates as antitumor agents.
      PubDate: 2017-12-22T04:50:12.588472-05:
      DOI: 10.1002/aoc.4164
       
  • Synthesis, spectroscopic evaluation, molecular modelling, thermal study
           and biological evaluation of manganese(II) complexes derived from
           bidentate N,O and N,S donor Schiff base ligands
    • Authors: Savita Bargujar; Sulekh Chandra, Reeta Chauhan, Hament K. Rajor, Jyoti Bhardwaj
      Abstract: Manganese(II) complexes having the general composition Mn(L)2X2 (where L = 3-bromoacetophenone semicarbazone, 3-bromoacetophenone thiosemicarbazone, 1-tetralone semicarbazone, 1-tetralone thiosemicarbazone, flavanone semicarbazone or flavanone thiosemicarbazone and X = Cl− or ½SO42−) were synthesized. All the complexes were characterized using elemental analyses, molar conductance and magnetic moment measurements, and mass, 1H NMR, infrared, electron paramagnetic resonance and electronic spectral studies. The molar conductance of the complexes in dimethylsulfoxide lies in the range 10–20 Ω−1 cm2 mol−1 indicating their non-electrolytic nature. All the complexes show magnetic moments corresponding to five unpaired electrons. The possible geometries of the complexes were assigned on the basis of electron paramagnetic resonance, electronic and infrared spectral studies. Some of the synthesized ligands and their complexes were screened for their antifungal activities against fungi Macrophomina phaseolina, Botrytis cinerea and Phoma glomerata using the food poison technique and their antibacterial activities against Xanthomonas campestris pv. campestris and Ralstonia solanacearum using the paper disc diffusion method. They showed appreciable activities.Graph showing activities of various ligands and complexes at different concentrations against the fungus Botritis cinerea.
      PubDate: 2017-12-22T04:32:46.892325-05:
      DOI: 10.1002/aoc.4149
       
  • Optimization of solid phase dispersive field-assisted ultrasonication for
           the extraction of auramine O and crystal violet dyes using central
           composite design
    • Authors: Faezeh Pourebrahim; Mehrorang Ghaedi, Kheibar Dashtian, Shadi Kheirandish, Alireza Goudarzi
      Abstract: Simultaneous preconcentration and determination of auramine o (AO) and crystal violet (CV) dyes from aqueous solution was conducted by ultrasound assisted (dispersive) solid phase microextraction (UASPME) based on SnO2/SnS composite loaded activated carbon (SnO2/SnS-NCs-AC). The prepared of SnO2/SnS-NCs-AC was characterized by FESEM and XRD analysis. Main and interaction influences of operational parameters such as pH, sonication time, amounts of sorbent, and type of eluent on extraction efficiency were investigated by central composite design and optimized with desirability function approach (DFA). ANOVA was conducted and shows that optimized values were found at 15.33 min sonication time, 0.019 g SnO2/SnS-NCs-AC mass, pH 5.46 and among different solvents, dimethyl formamide was selected as an efficient eluent. Under this conditions recoverees percentage were obtained 82.85% and 86.70% for AO and CV, respectively. Based on F-test under ANOVA all main effect and interaction effect of understudy parameters has the significant effect on the responses. At optimum conditions, limit of detection (0.0015 and 0.001 mg/l), limit of quantitation (0.4 and 0.4 mg/l), limit of linearity (9.0 and 9.0 mg/l), enrichment factor (33.48 and 83.71) and percent relative standard deviation (3.44 and 4.20) were found to be for auramine o and crystal violet dyes, respectively. Finally, the method was successfully applied for the preconcentration and determination of AO and CV in water samples and ER% of 89.0-97.0 and 96.2–98.0% as acceptable range were found to be for AO and CV samples, respectively.Simultaneous preconcentration and determination of auramine o (AO) and crystal violet (CV) dyes from aqueous solution was conducted by ultrasound assisted (dispersive) solid phase microextraction (UASPME) based on SnO2/SnS composite loaded activated carbon (SnO2/SnS-NCs-AC).
      PubDate: 2017-12-22T03:38:26.222372-05:
      DOI: 10.1002/aoc.4181
       
  • Visible light driven amide synthesis in water at room temperature from
           
    • Authors: Sudipto Das; Shounak Ray, Abhisek Brata Ghosh, Partha Kumar Samanta, Suvendu Samanta, Bibhutosh Adhikary, Papu Biswas
      Abstract: Highly efficient photocatalytic thioacid mediated amide synthesis at room temperature using CdS nanoparticles as photocatalyst was observed under a household 30 W CFL in water. The operationally mild reaction was tolerant to a number of functional group substitutions on amine and could be scaled up to gram. This heterogeneous photocatalyst was extremely stable and could easily be recovered by simple centrifugation for at least six recycling reactions without any significant loss of catalytic performance. The possible reaction mechanism for the photocatalytic thioacid mediated amide synthesis over the CdS semiconductor has also been proposed on the basis of experimental observations.Efficient photocatalytic thioacid mediated amide synthesis at room temperature using CdS nanoparticles as photocatalyst has been performed under visible light irradiation in water.
      PubDate: 2017-12-22T03:37:00.834444-05:
      DOI: 10.1002/aoc.4199
       
  • Hierarchical TiO2 nanosheet-assembled nanotubes with dual electron sink
           functional sites for efficient photocatalytic degradation of rhodamine B
    • Authors: Chao Zhang; Yuming Zhou, Jiehua Bao, Yiwei Zhang, Shuo Zhao, Jiasheng Fang, Wenxia Chen, Xiaoli Sheng
      Abstract: A novel Pt–TiO2/Ag nanotube photocatalyst has been synthesized successfully via a facile method. TiO2 nanotubes are assembled with numerous ultrathin TiO2 nanosheets and show a highly open structure. The gaps between adjacent TiO2 nanosheets can serve as channels for the access of reactants, accelerating the mass transfer process. During the fabrication process of the Pt–TiO2/Ag nanotube photocatalyst, high-quality Pt–SiO2 nanotubes are synthesized first with the structure-directing effect of polyvinylpyrrolidone. Then a TiO2 layer is coated on the outside surface of the silica nanotubes. The introduced titanium species can be converted into TiO2 nanosheet structure during the subsequent hydrothermal treatment, gradually constructing nanosheet-assembled nanotubes. Lastly, after the introduction of another electron sink function site of Ag through UV irradiation, the Pt–TiO2/Ag nanotube photocatalyst with dual electron sink functional sites is obtained. The specially doped Pt and Ag NPs can simultaneously inhibit the recombination process of photogenerated charge carriers and increase light utilization efficiency. Therefore, the as-synthesized Pt–TiO2/Ag nanotube catalyst exhibits a high photocatalytic degradation performance for rhodamine B of 0.2 min−1, which is about 3.2 and 5.3 times as high as that of Pt–TiO2 and TiO2 nanotubes because of the enhanced charge carrier separation efficiency. Furthermore, in the unique nanoarchitecture, the nanotubes are assembled with numerous ultrathin TiO2 nanosheets, which can absorb abundant active species and dye molecules for photocatalytic reaction. On the basis of experimental results, a possible rhodamine B degradation mechanism is proposed to explain the excellent photocatalytic efficiency of the Pt–TiO2/Ag nanotube photocatalyst.As-obtained nanotubes are assembled with numerous ultrathin TiO2 nanosheets. Pt and Ag nanoparticles could serve as electron sink function for photocatalysis simultaneously. The nanotubes show a large surface area and highly open structure.
      PubDate: 2017-12-22T03:30:14.462633-05:
      DOI: 10.1002/aoc.4204
       
  • Cover Image
    • Authors: Lin Tang; Chaoting Wu, Qiyan Hu, Qian Li, Wu Zhang
      Abstract: The cover image, by Lin Tang et al., is based on the Full Paper Cross-coupling reactions using porous multipod Cu2O microcrystals as recoverable catalyst in aqueous media.
      DOI : 10.1002/aoc.3980.
      PubDate: 2017-12-20T01:18:50.612505-05:
       
  • Issue Information
    • Abstract: No abstract is available for this article.
      PubDate: 2017-12-20T01:18:49.236639-05:
      DOI: 10.1002/aoc.4083
       
  • Pd-catalyzed Desulfitative reaction of Aryltrifluoroborates with sodium
           Arenesulfinates in water
    • Authors: Sheng Chang; Yong Bing Sun, Xiu Rong Zhang, Lin Lin Dong, He Yun Zhu, Hong Wei Lai, Dan Wang
      Abstract: An efficient procedure for the synthesis of biaryls was catalyzed by Pd(CH3CN)4(BF4)2 is reported. This Pd-catalyzed cross-coupling reaction of aryltrifluoroborates with sodium arenesulfinates was developed under mild and environmentally benign conditions, in water without any ligand or additive. The reaction gave a range of structurally diverse unsymmetrical bi-aryl molecules with excellent yields, in which the byproduct was sulfur dioxide. It is worth noting that this protocol is also applicable to many heterocyclic aromatics such as thiophene, furan, pyridine, quinoline, isoquinoline and indole.An efficient procedure for the synthesis of biaryls was catalyzed by Pd(CH3CN)4(BF4)2 is reported. This Pd-catalyzed cross-coupling reaction of aryltrifluoroborates with sodium arenesulfinates was developed under mild and environmentally benign conditions, in water without any ligand or additive. The reaction gave a range of structurally diverse unsymmetrical bi-aryl molecules including many heterocyclic aromatics with good yields, in which the byproduct was sulfur dioxide.
      PubDate: 2017-10-16T03:26:33.93373-05:0
      DOI: 10.1002/aoc.3970
       
  • Synthesis, characterization and solid-phase extraction properties of novel
           bis(diazo-azomethine) ligands supported on mesoporous silica
    • Authors: Serhan Uruş; Muharrem Karabörk, Hüseyin Köksal
      Abstract: The novel mesoporous silica-supported bis(diazo-azomethine) compounds have been synthesized and characterized successively. In the first step, 1,3-phenylenedimethanamine and 4,4′-diaminodiphenylmethane were diazotized, and the obtained bis(diazonium) cations were coupled with 2,4-dihydroxybenzaldehyde. The synthesized bis(diazo-carbonyl) compounds, 5,5′-((1,3-phenylenebis(methylene))bis(diazene-2,1-diyl))bis(2,4-dihydroxybenzaldehyde) (A1) and 5,5′-((methylenebis(4,1-phenylene))bis(diazene-2,1-diyl))bis(2,4-dihydroxybenzaldehyde) (A2) were chemically supported on amino-modified silica-gel (as L1 and L2). Elemental analysis, liquid chromatography-mass spectroscopy, liquid-phase NMR (1H and 13C) and solid-phase NMR (CP-MAS 29Si and 13C), FT-IR, TG/DTA, scanning electron microscopy and energy-dispersive X-ray spectroscopy techniques were used for characterizations of all the synthesized compounds. The syringe and batch techniques were applied for the solid-phase extraction properties of Pb(II), Cu(II), Cd(II) and Cr(III) ions using an inductively coupled plasma-atomic emission spectroscopy instrument. The recoveries of Pb(II), Cu(II), Cd(II) and Cr(III) ions have been achieved to 95–99% with the (RSDs) of ± 2–3% in optimum conditions.Synthesis of novel bis(diazo-azomethine) ligands supported on mesoporous silica.Effective adsorbents for metal ions in water samples.
      PubDate: 2017-10-04T03:47:20.440391-05:
      DOI: 10.1002/aoc.4022
       
  • Synthesis and characterization of antibacterial chromium iron oxide
           nanoparticle-loaded activated carbon for ultrasound-assisted wastewater
           treatment
    • Authors: Ali Akbar Bazrafshan; Shaaker Hajati, Mehrorang Ghaedi, Arash Asfaram
      Abstract: The aim of this study was to evaluate the surface adsorption capacity of CrFeO3 nanoparticle-loaded activated carbon (CrFeO3-NPs–AC) for the removal of a cationic dye (methyl violet, MV). CrFeO3-NPs were hydrothermally synthesized and loaded on AC followed by characterization using X-ray diffraction, field-emission scanning electron microscopy and energy-dispersive and Fourier transform infrared spectroscopies. The CrFeO3-NPs were tested for in vitro antibacterial activities against Gram-positive (Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa) bacteria. Minimum inhibitory and minimum bactericidal concentrations of CrFeO3-NPs–AC were obtained to be 50 and 100 μg ml−1, respectively, against S. aureus and 25 and 50 μg ml−1 against P. aeruginosa. These results indicated the antibacterial properties of CrFeO3-NPs–AC. To investigate the adsorption process, several systematic experiments were designed by varying parameters such as adsorbent mass, pH, initial MV concentration and sonication time. The adsorption process was modelled and the optimal conditions were determined to be 0.013 g, 7.4, 15 mg l−1 and 8 min for adsorbent mass, pH, MV concentration and sonication time, respectively. The real experimental data were found to be efficiently explained by response surface methodology and genetic algorithm model. Kinetic studies for MV adsorption showed rapid sorption dynamics described by a second-order kinetic model, suggesting a chemisorption mechanism. Then, the experimental equilibrium data obtained at various concentrations of MV and adsorbent masses were fitted to conventional Langmuir, Freundlich, Temkin and Dubinin–Radushkevich isotherm models. Dye adsorption equilibrium data were fitted well to the Langmuir isotherm. From the Langmuir model, the maximum monolayer capacity was calculated to be 65.67 mg g−1 at optimum adsorbent mass.The surface adsorption capacity of CrFeO3 nanoparticles-loaded activated carbon (CrFeO3-NPs–AC) for the removal of cationic dye (methyl violet; MV) was studied. CrFeO3-NPs were hydrothermally synthesized and loaded on activated carbon (AC) followed by their test for in-vitro antibacterial activities against gram-positive (Staphylococcus aureus) and gram-negative (Pseudomonas aeruginosa) bacteria.
      PubDate: 2017-09-20T06:27:24.255871-05:
      DOI: 10.1002/aoc.3981
       
  • Hiyama cross-coupling reaction using Pd(II) nanocatalyst immobilized on
           the surface of Fe3O4@SiO2
    • Authors: Kazem Karami; Nasrin Jamshidian, Mohammad Mehdi Nikazma, Pablo Hervés, Amir Rezaei Shahreza, Ali Karami
      Abstract: We report a simple process for the synthesis of Fe3O4@SiO2/APTMS (APTMS = 3-aminopropyltrimethoxysilane) core–shell nanocatalyst support. The new nanocatalyst was prepared by stabilization of Pd(cdha)2 (cdha = bis(2-chloro-3,4-dihydroxyacetophenone)) on the surface of the Fe3O4@SiO2/APTMS support. The structure and composition of this catalyst were characterized using various techniques. An efficient method was developed for the synthesis of a wide variety of biaryl compounds via fluoride-free Hiyama cross-coupling reactions of aryl halides with arylsiloxane, with Fe3O4@SiO2/APTMS/Pd(cdha)2 as the catalyst under reaction conditions. This methodology can be performed at 100°C through a simple one-pot operation using in situ generated palladium nanoparticles. High catalytic activity, quick separation of catalyst from products using an external magnetic field and use of water as green solvent are attributes of this protocol.A new nanocatalyst was prepared by stabilization of Pd(cdha)2 in the surface of Fe3O4@SiO2/APTMS support. High yields of products, as well as high stereoselectivity, high speed of the reaction and use of water as the solvent to additional eco-friendly attribute are important features in the fluoride-free Hiyama cross coupling reaction.
      PubDate: 2017-09-20T06:16:44.50423-05:0
      DOI: 10.1002/aoc.3978
       
  • Fe3O4@SiO2–ZrCl2-MNPs: A novel magnetic catalyst for the clean and
           efficient cascade synthesis of 1-(benzothiazolylamino)methyl-2-naphthol
           derivatives in the absence of solvent
    • Authors: Fatemeh Kamali; Farhad Shirini
      Abstract: A green, simple and eco-friendly three-component condensation for the synthesis of 1-(benzothiazolylamino)methyl-2-naphthols using new magnetic nanoparticles formulated as Fe3O4@SiO2–ZrCl2-MNPs is described. Considering the economic and environmental aspects, the method provides some advantages such as clean procedure, solvent-free conditions, simple operation and work-up, relatively short reaction times and high yields of the products. Moreover the introduced catalyst can be readily recovered up to 4 consecutive runs with consistent activity using an external magnet.A green, simple and eco-friendly three-component condensation for the synthesis of 1-(benzothiazolylamino)methyl-2-naphthols using new magnetic nanoparticles formulated as Fe3O4@SiO2–ZrCl2-MNPs is described.
      PubDate: 2017-09-11T03:00:44.345672-05:
      DOI: 10.1002/aoc.3972
       
  • Co(II) anchored glutaraldehyde crosslinked magnetic chitosan nanoparticles
           (MCS) for synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted
           imidazoles
    • Authors: Harminder Singh; Jaspreet Kaur Rajput
      Abstract: A simple, highly efficient and green synthesis of 2,4,5-trisubsituted and 1,2,4,5-tetrasubstituted imidazoles was developed using a novel MCS-GT@Co(II) magnetically recoverable and recyclable catalyst under refluxing conditions with ethanol as a solvent. The catalyst was prepared by immobilization of chitosan onto Fe3O4 using glutaraldehyde as crosslinker followed by Co(II) ion immobilization via cobalt acetate. The catalyst was characterized using various techniques. For organic products determination, 1H NMR, 13C NMR and Fourier transform infrared spectroscopies were used. The reaction was also tried with individual components of the catalyst, but the synergistic effect of the components in the prepared catalyst showed the highest yield and shortest reaction time.A green, novel and cost effective method of synthesis of MCS-GT-Co(II) nanoparticles is successfully developed and further they are used as a heterogeneous catalyst in the synthesis of tri and tetrasubstituted imidazoles. This method has advantages like short reaction time, high yield of product, simple work up, recyclable and reusable magnetic catalyst.
      PubDate: 2017-09-08T05:07:49.598563-05:
      DOI: 10.1002/aoc.3989
       
  • Sonophotocatalytic treatment of diazinon using visible light-driven
           Ce:Cu-1,4-BDOAH2 photocatalyst in a batch-mode process: Response surface
           methodology and optimization
    • Authors: T. Taghipour; G.R. Karimipour, M. Ghaedi, M.R. Rahimi, S. Mosleh
      Abstract: Cu–1,4-benzenedioxyacetic acid (Cu-1,4-BDOAH2) with a narrow band gap (2.52 eV) was synthesized and doped with Ce to afford Ce:Cu-1,4-BDOAH2 as an efficient photocatalyst with narrower band gap (2.39 eV). The prepared Cu-1,4-BDOAH2 and Ce:Cu-1,4-BDOAH2 were characterized using Fourier transform infrared, energy-dispersive X-ray, diffuse reflectance spectroscopies, scanning electron microscopy and X-ray diffraction. The sonophotocatalytic degradation of diazinon was carried out in a batch-mode reactor using visible light-driven Ce:Cu-1,4-BDOAH2 photocatalyst as well as ultrasonic irradiation. The narrow band gap of the photocatalyst means that it can be activated under visible light illumination. The effects of operational parameters such as initial diazinon concentration (5–25 mg l−1), pH (2–10), photocatalyst dosage (10–30 mg) and irradiation time (10–30 min) on the sonophotocatalytic degradation efficiency were investigated using central composite design under response surface methodology. The optimization process was studied using desirability function and the results indicated 99.8% degradation, which was obtained at optimum values of 25 mg l−1, 6, 20 mg and 20 min for the initial concentration of diazinon, pH, photocatalyst dosage and irradiation time, respectively. Reusability experiments of Ce:Cu-1,4-BDOAH2 photocatalyst showed that it is quite stable with excellent catalytic activity even after five cycles.Cu-1,4-BDOAH2 was synthesized and doped with Ce to afford Ce:Cu-1,4-BDOAH2 as a new photocatalyst. Ce:Cu-1,4-BDOAH2 was used for sonophotocatalytic degradation of diazinon in a batch -mode reactor using visible light. The effects of operational parameters on the sonophotocatalytic degradation efficiency were investigated using central composite design under response surface methodology. The optimization process was studied using desirability function and the results indicated 99.8% degradation, which was obtained at optimal condition.
      PubDate: 2017-09-05T22:51:41.440295-05:
      DOI: 10.1002/aoc.3962
       
  • Preparation of an organic–inorganic hybrid based on synergy of Brønsted
           and Lewis acid centres as heterogeneous magnetic nanocatalyst for
           ultrafast synthesis of acetaminophen
    • Authors: M. Kooti; E. Nasiri
      Abstract: A heterogeneous nanocatalyst based on a Cu(II) complex containing phosphotungstic acid and N/O-donor ligands supported on cobalt ferrite nanoparticles was successfully prepared. The synthesized nanocatalyst was characterized using various techniques. The magnetic nanocatalyst was examined as an efficient and synergistic catalyst for ultrafast synthesis of acetaminophen at room temperature and under solventless conditions. The examined synergistic nanocatalyst, which has both Lewis and Brønsted acidic sites, could be easily separated from the reaction system and reused several times without significant loss of its activity. The synthesized acetaminophen was also fully characterized.A novel copper complex with phosphotungstic acid and N/O donor ligands was supported on cobalt ferrite NPs and used as efficient catalyst for ultrafast synthesis of acetaminophen. Both the catalyst and acetaminophen have been fully ccharacterized.The nanocatalyst could be easily recovered and reused for several times without loss of its activity.
      PubDate: 2017-08-31T06:17:19.926032-05:
      DOI: 10.1002/aoc.3990
       
  • Synthesis of pyranopyrazoles using
           nano-Fe-[phenylsalicylaldiminemethylpyranopyrazole]Cl2 as a new Schiff
           base complex and catalyst
    • Authors: Ahmad Reza Moosavi-Zare; Hamid Goudarziafshar, Khadijeh Saki
      Abstract: By the condensation reaction of benzaldehyde with ethyl acetoacetate, malononitrile and hydrazine hydrate in the presence of FeCl2, a pyranopyrazole derivative was prepared which was then reacted with salicylaldehyde to afford nano-Fe-[phenylsalicylaldiminemethylpyranopyrazole]Cl2 (nano-[Fe-PSMP]Cl2). The prepared nano-Schiff base complex was fully characterized using Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, differential thermogravimetry, scanning electron microscopy and UV–visible spectroscopy, and was used as an efficient and catalyst for the preparation of pyranopyrazoles.Nano-Fe-[phenyl-salicylaldimine-methylpyranopyrazole]Cl2 as a new nano-Schiff base complex and catalyst was prepared, identified and applied for the preparation of pyranopyrazoles.
      PubDate: 2017-08-25T06:20:45.297416-05:
      DOI: 10.1002/aoc.3968
       
  • A tridentate CNO-donor palladium(II) complex as efficient catalyst for
           direct C―H arylation: Application in preparation of imidazole-based
           push–pull chromophores
    • Authors: Hui-Hong Li; Ratnava Maitra, Ya-Ting Kuo, Jie-Hong Chen, Ching-Han Hu, Hon Man Lee
      Abstract: A series of imidazolium chlorides for the formation of tridentate CNO-donor palladium(II) complexes featuring N-heterocyclic carbene moieties have been developed from cheap and readily available starting materials with high yields. Their palladium complexes were prepared by reactions between the ligand precursors and PdCl2 using K2CO3 as base in pyridine with reasonable yields. These air-stable metal complexes were characterized using 1H NMR and 13C{1H} NMR spectroscopy and elemental analyses. Heteronuclear multiple bond correlation experiments were performed to identify key NMR signals of these compounds. The structures of two of the complexes were also established by single-crystal X-ray diffraction analysis. One of these complexes was successfully applied in the direct C―H functionalization reactions between heterocyclic compounds and aryl bromides, producing excellent yields of coupled products. The coupling reactions were scalable, allowing grams of coupled products to be obtained with a mere 2 mol% of Pd loading. The catalyst system developed allowed the large-scale preparation of several push–pull chromophores straightforwardly. Photophysical properties based on UV–visible and fluorescence spectroscopy for these chromophores were investigated. Deep blue photoluminescence with moderate quantum efficiency and twisted intramolecular charge transfer excited state were observed for these chromophores. Density functional theory (DFT) and time-dependent DFT calculations were performed to support the experimental results.A tridentate CNO-donor palladium(II) complex featuring an N-heterocyclic carbene moiety was developed as an efficient catalyst for direct C―H arylation between heterocyclic compounds and aryl bromides. The catalyst system allowed large-scale preparation of several push–pull chromophores straightforwardly with a mere 2 mol% of Pd loading.
      PubDate: 2017-08-25T05:32:15.586936-05:
      DOI: 10.1002/aoc.3956
       
  • Selective detection of Hg2+ ion in aqueous medium with the use of
           3-(pyrimidin-2-ylimino)indolin-2-one-functionalized SBA-15
    • Authors: Negar Lashgari; Alireza Badiei, Ghodsi Mohammadi Ziarani
      Abstract: An isatin-based fluorophore, 3-(pyrimidin-2-ylimino)indolin-2-one, was grafted on a large-pore mesoporous silica material (SBA-15) via a two-step modification process. The obtained material (SBA-Is-Py) was characterized using various techniques and the characterization showed that the ordered porous structure was preserved after the post-grafting procedure. The optical sensing ability of SBA-Is-Py was studied upon the addition of a variety of metal ions and a marked fluorescence quenching by Hg2+ ion was observed. SBA-Is-Py exhibited excellent Hg2+-specific luminescence quenching over various competing cations. Furthermore, linear changes of the optical properties of SBA-Is-Py as a function of the concentrations of Hg2+ ion were found, with a calculated detection limit of 3.28 × 10−7 M. In addition, SBA-Is-Py was successfully employed for the determination of Hg2+ in real water samples.An isatin based fluorophore, (3-(pyrimidin-2-ylimino)indolin-2-one), was grafted on a mesoporous silica material (SBA-15) via a two-step modification process. The optical sensing ability of SBA-Is-Py was studied upon the addition of a variety of metal ions and a remarkable fluorescence quenching by Hg2+ ion was observed. SBA-Is-Py exhibited excellent Hg2+-specific luminescence quenching over various competitive cations. Furthermore, linear changes of the optical properties of SBA-Is-Py as a function of the concentrations of Hg2+ ion were proved.
      PubDate: 2017-08-25T05:21:39.004327-05:
      DOI: 10.1002/aoc.3991
       
  • Ferrocene-tagged ionic liquid stabilized on silica-coated magnetic
           nanoparticles: Efficient catalyst for the synthesis of
           2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions
    • Authors: Reza Teimuri-Mofrad; Mahdi Gholamhosseini-Nazari, Elmira Payami, Somayeh Esmati
      Abstract: An advanced novel magnetic ionic liquid based on imidazolium tagged with ferrocene, a supported ionic liquid, is introduced as a recyclable heterogeneous catalyst. Catalytic activity of the novel nanocatalyst was investigated in one-pot three-component reactions of various aldehydes, malononitrile and 2-naphthol for the facile synthesis of 2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions without additional co-catalyst or additive in air. For this purpose, we firstly synthesized and investigated 1-(4-ferrocenylbutyl)-3-methylimidazolium acetate, [FcBuMeIm][OAc], as a novel basic ferrocene-tagged ionic liquid. This ferrocene-tagged ionic liquid was then linked to silica-coated nano-Fe3O4 to afford a novel heterogeneous magnetic nanocatalyst, namely [Fe3O4@SiO2@Im-Fc][OAc]. The synthesized novel catalyst was characterized using 1H NMR, 13C NMR, Fourier transform infrared and energy-dispersive X-ray spectroscopies, X-ray diffraction, and transmission and field emission scanning electron microscopies. Combination of some unique characteristics of ferrocene and the supported ionic liquid developed the catalytic activity in a simple, efficient, green and eco-friendly protocol. The catalyst could be reused several times without loss of activity.An advanced novel magnetic ionic liquid based on imidazolium tagged with ferrocene was designed and synthesized as a recyclable heterogeneous catalyst. The activity of the nanocatalyst was investigated for the facile synthesis of 2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions.
      PubDate: 2017-08-25T05:15:55.189493-05:
      DOI: 10.1002/aoc.3955
       
  • Nitro group reduction and Suzuki reaction catalysed by palladium supported
           on magnetic nanoparticles modified with carbon quantum dots generated from
           glycerol and urea
    • Authors: Mohammad Gholinejad; Fatemeh Zareh, Carmen Nájera
      Abstract: Glycerol and urea were used as green and cheap sources of carbon quantum dots (CQD) for modifying Fe3O4 nanoparticles (NPs). The obtained CQD@Fe3O4 NPs were used for the stabilization of palladium species and the prepared catalyst, Pd@CQD@Fe3O4, was characterized using various techniques. This magnetic supported palladium was applied as an efficient catalyst for the reduction of aromatic nitro compounds to primary amines at room temperature using very low palladium loading (0.008 mol%) and also for the Suzuki–Miyaura cross-coupling reaction of aryl halides as well as challenging heteroaryl bromides and aryl diazonium salts with arylboronic acids and with potassium phenyltrifluoroborate. This magnetically recyclable catalyst was recovered and reused for seven consecutive runs in the reduction of 4-nitrotoluene to p-toluidine and for ten consecutive runs in the reaction of 4-iodoanisole with phenylboronic acid with small decrease of activity. The catalyst reused in the Suzuki reaction was characterized using transmission electron microscopy, vibrating sample magnetometry and X-ray photoelectron spectroscopy. Using experiments such as hot filtration and poisoning tests, it has been shown that the true catalyst works under homogeneous conditions according to the release–return pathway of active palladium species.A new sustainable magnetic carbon quantum dot-supported palladium catalyst was prepared and applied in reduction and Suzuki reactions.
      PubDate: 2017-08-25T05:11:46.819238-05:
      DOI: 10.1002/aoc.3984
       
  • Application of novel copper organic material for facile microextraction of
           sodium valproate from human plasma samples: Experimental design
           optimization and isotherm study
    • Authors: Sonia Bahrani; Mehrorang Ghaedi, Tahere Taghipour, Mohammad Javad Khoshnood Mansoorkhani, Ahmad Reza Bagheri, Abbas Ostovan
      Abstract: Well-designed metal organic materials (MOMs) were synthesized and applied for pre-concentration and determination of sodium valproate (Na-VP) from biological samples, bound to the copper complex of 1,4-phenylenedioxydiacetic acid under mild conditions. The channels of this sorbent provide high efficiency and also selectivity. The MOMs were structurally characterized using Fourier transform infrared and energy-dispersive X-ray spectroscopies, scanning electron microscopy and X-ray diffraction, and they were found to have suitable features for quantification of Na-VP using HPLC coupled with UV detection at λ = 215 nm. Moreover, the rate of adsorption is improved by ultrasonic power and the experimental data are best fitted according to Freundlich adsorption isotherm. According to the central composite design, the best experimental conditions are 280.0 μl, 3.0 min and 17.0 mg for volume of eluent, sonication time and sorbent mass respectively. Calibration plots show linear responses towards Na-VP concentrations (0.4–18.0 μg ml−1), satisfactory limit of detection (0.06 μg ml−1, S/N = 3) and reasonable enrichment factor (70.58). The coefficient of variation values of both inter- and intra-day analyses were less than 4.0%, indicating a candidate method for the determination of Na-VP in human plasma with reasonable recovery and efficiency.Well-designed metal organic materials (MOMs) were synthesized and applied for pre-concentration and determination of sodium valproate (Na-VP) from biological samples, bound to the copper complex of 1,4-phenylenedioxydiacetic acid under mild conditions. The channels of this sorbent provide high efficiency and also selectivity.
      PubDate: 2017-08-25T05:00:41.624639-05:
      DOI: 10.1002/aoc.3960
       
  • Preparation of Fe3O4@5,10-dihydropyrido[2,3-b]quinoxaline-7,8-diol copper
           complex: A capable nanocatalyst for the green synthesis of 1-substituted
           1H-tetrazoles
    • Authors: Davood Habibi; Narges Pakravan, Ameneh Arabi, Zahra Kaboudvand
      Abstract: Fe3O4 magnetic nanoparticles functionalized with 5,10-dihydropyrido[2,3-b]quinoxaline-7,8-diol were synthesized as was their complex with copper as a novel nanomagnetic iron oxide catalyst via a simple and green method, and characterized using various techniques. The capability of the catalyst was evaluated in the one-pot three-component synthesis of different tetrazoles, which showed very good results. Mild reaction conditions, good reusability and simple magnetic work-up make this methodology interesting for the efficient synthesis of tetrazoles.Fe3O4 magnetic nanoparticles functionalized with 5,10-dihydropyrido[2,3-b] quinoxaline-7,8-diol were synthesized as was their complex with copper as a novel nanomagnetic iron oxide catalyst via a simple and green method. The capability of the catalyst was evaluatedin the one-pot three-component synthesis of different tetrazoles, which showed very good results.
      PubDate: 2017-08-25T04:55:54.842524-05:
      DOI: 10.1002/aoc.3988
       
  • Facile fabrication of ZnO/N-doped helical carbon nanotubes composites with
           enhanced photocatalytic activity toward organic pollutant degradation
    • Authors: Shuaishuai Ma; Qing Li, Zhilan Cai, Zhaolian Ye, Yuming Zhou
      Abstract: Novel ZnO/N-doped helical carbon nanotubes (ZnO/N-HCNTs) composites were successfully synthesized via a facile chemical precipitation approach at room temperature. The sample was well characterized by X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM) and ultraviolet–visible diffuse reflectance spectroscopy (UV–vis DRS). The photocatalytic activity was evaluated in the degradation of methylene blue (MB) aqueous solution under UV light irradiation. It is found that ZnO nanoparticles were highly and uniformly anchored on the surface and inner tubes of the N-HCNTs with size of about 5 nm, and significantly enhanced the photocatalytic activity compared to pure ZnO. The enhanced photocatalytic activity of ZnO/N-HCNTs composites can be ascribed to the integrative synergistic effect of effective interfacial hybridization between N-HCNTs and ZnO nanoparticles and the prolonged lifetime of photogenerated electron–hole pairs. Moreover, the ZnO/N-HCNTs could be easily recycled without any obvious decrease in photocatalytic activity and could be promote their application in the area of environmental remediation.Novel ZnO/N-doped helical carbon nanotubes (ZnO/N-HCNTs) composites were successfully synthesized via a facile chemical precipitation approach at room temperature. It is found that ZnO nanoparticles were highly and uniformly anchored on the surface and inner tubes of the N-HCNTs with size of about 5 nm, and significantly enhanced the photocatalytic activity compared to pure ZnO.
      PubDate: 2017-08-22T04:31:56.537994-05:
      DOI: 10.1002/aoc.3966
       
  • Novel ionic liquid supported on Fe3O4 nanoparticles as an efficient
           catalyst for the synthesis of new chromenes
    • Authors: Javad Safaei-Ghomi; Fahime Eshteghal, Hossein Shahbazi-Alavi
      Abstract: An efficient procedure for the synthesis of new chromenes by the multicomponent reaction of aldehydes, 4-hydroxycoumarin and 2-hydroxynaphthalene-1,4-dione in the presence of an ionic liquid supported on Fe3O4 nanoparticles is described. The ionic liquid supported on Fe3O4 nanoparticles as a magnetic catalyst gives products in high yields. Significant features of this method are: short reaction times, excellent yields, green method and use of an effective catalyst that can be recovered and reused many times without loss of its catalytic activity.A novel ionic liquid (IL) supported on Fe3O4 magnetic nanoparticles (MNPs) has been successfully prepared and characterized. These MNPs were used as an efficient heterogeneous catalyst for the one-pot three-component synthesis of new chromenes in ethanol–water at 50 °C.
      PubDate: 2017-08-22T04:31:32.629377-05:
      DOI: 10.1002/aoc.3987
       
  • Excellent alkene epoxidation catalytic activity of macrocyclic-based
           complex of dioxo-Mo(VI) on supermagnetic separable nanocatalyst
    • Authors: Fatemeh Payami; Abolfazl Bezaatpour, Habibollah Eskandari
      Abstract: A phenoxybutane-based Schiff base complex of cis-dioxo-Mo(VI) was supported on paramagnetic nanoparticles and characterized using powder X-ray diffraction, infrared, diffuse reflectance and atomic absorption spectroscopies, scanning and transmission electron microscopies and vibrating sample magnetometry. The separable nanocatalyst was tested for the selective epoxidation of cyclohexene, cyclooctene, styrene, indene, α-pinene, 1-octene, 1-heptene, 1-dodecene and trans-stilbene using tert-butyl hydroperoxide (80% in di-tert-butyl peroxide–water, 3:2) as oxidant in chloroform. The catalyst was efficient for oxidation of cyclooctene with 100% selectivity for epoxidation with 98% conversion in 10 min. We were able to separate magnetically the nanocatalyst using an external magnetic field and used the catalyst at least six successive times without significant decrease in conversion. The turnover frequency of the catalyst was remarkable (2556 h−1 for cyclooctene). The proposed nanomagnetic catalyst has advantages in terms of catalytic activity, selectivity, catalytic reaction time and reusability by easy separation.Phenoxy butane based Schiff base complex of Cis-dioxo-Mo(VI) was supported on nanoparticles and characterized by physico-chemical spectroscopy. The catalyst was tested for the selective epoxidation of olefins using TBHP in chloroform. This catalyst is efficient for oxidation of cyclooctene with 100% selectivity for epoxidation with 98% conversion in 10 min. The turn over frequency of catalyst is so remarkable (2556 h−1 for cyclooctene).
      PubDate: 2017-08-22T04:25:53.747807-05:
      DOI: 10.1002/aoc.3986
       
  • Chemo-selective reduction of nitro and nitrile compounds using Ni
           nanoparticles immobilized on hyperbranched polymer-functionalized magnetic
           nanoparticles
    • Authors: Seyed Jamal Tabatabaei Rezaei; Asemeh Mashhadi Malekzadeh, Sima Poulaei, Ali Ramazani, Hossein Khorramabadi
      Abstract: The nitro and nitrile groups in aromatic and aliphatic compounds containing various reducible substituents such as carboxylic acid, ketone, aldehyde and halogen are selectively reduced to the corresponding amines in water as a green solvent with excellent yields by employing NaBH4 in the presence of Fe3O4@PAMAM/Ni(0)-b-PEG nanocatalyst. The morphology and structural features of the catalyst were characterized using various microscopic and spectroscopic techniques. The designed catalyst system because of it being covered with hydrophilic polymers is soluble in a wide range of solvents (e.g. water and ethanol) and suitable for immobilizing and stabilizing Ni nanoparticles in aqueous mediums. In addition, the catalyst can be easily recovered from a reaction mixture by applying an external magnetic field and can be reused up to six runs without significant loss of activity.We have developed a novel magnetically recoverable nickel-based semi-heterogeneous catalytic system (Fe3O4@PAMAM/Ni(0)-b-PEG) for the selective reduction of nitro and nitrile groups in aromatic and aliphatic compounds containing various reducible substituents to the corresponding amines in water as a green solvent.
      PubDate: 2017-08-22T04:20:48.122997-05:
      DOI: 10.1002/aoc.3975
       
  • Copper containing nanosilica thioalated dendritic material: A recyclable
           catalyst for synthesis of benzimidazoles and benzothiazoles
    • Authors: Maryam Zakeri; Majid Moghadam, Valiollah Mirkhani, Shahram Tangestaninejad, Iraj Mohammadpoor-Baltork, Zari Pahlevanneshan
      Abstract: In this paper, the design and characterization of a new heterogeneous catalyst by incorporation of copper ions into the nanosilica modified by thiole–based dendrimer are reported. The prepared catalyst was characterized by FT–IR, TGA, elemental analysis, FE–SEM, TEM, XPS and ICP–OES techniques. This material was used as catalyst in the synthesis benzimidazoles and benzothiazoles by the reaction of substituted benzaldehydes with 1,2–diaminobenzene or 2–aminothiophenol, respectively. The advantages of the present catalytic system are high yields, mild conditions and short reaction times. On the other hand, this new synthesized catalyst was recycled very well and reused several times without significant loss of its catalytic activity.The synthesis and characterization of Cu(II) containing thiolated dendrimer on nanosilica have been described. The prepared catalyst was characterized by FT-IR, UV–Vis, TGA, elemental analysis, ICP-OES, TEM, FE-SEM and XPS techniques. The Cu(II)-TD@nSiO2 has been used as an efficient catalyst for the preparation of various benzimidazoles and benzothiazoles under mild conditions. Furthermore, the catalyst is stable under the reaction conditions and can be recycled and reused several times without a significant loss in activity.
      PubDate: 2017-08-22T04:15:41.044032-05:
      DOI: 10.1002/aoc.3937
       
  • Highly efficient oxidative cleavage of alkenes and cyanosilylation of
           aldehydes catalysed by magnetically recoverable MIL-101
    • Authors: Maryam Nourian; Farnaz Zadehahmadi, Reihaneh Kardanpour, Shahram Tangestaninejad, Majid Moghadam, Valiollah Mirkhani, Iraj Mohammadpoor-Baltork
      Abstract: The catalytic activity of magnetically recoverable MIL-101 was investigated in the oxidation of alkenes to carboxylic acids and cyanosilylation of aldehydes. MIL-101 was treated with Fe3O4 and the prepared catalyst was characterized using Fourier transform infrared spectroscopy, X-ray diffraction, N2 adsorption measurements, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy and inductively coupled plasma analysis. The catalytic active sites in this heterogeneous catalyst are Cr3+ nodes of the MIL-101 framework. This heterogeneous catalyst has the advantages of excellent yields, short reaction times and reusability several times without significant decrease in its initial activity and stability in both oxidation and cyanosilylation reactions. Its magnetic property allows its easy separation using an external magnetic field.Magnetically recoverable catalysts are of great interest. In this paper, the catalytic activity of magnetically recoverable MIL-101 was investigated in the oxidation of alkenes to carboxylic acids and cyanosilylation of aldehydes.
      PubDate: 2017-08-22T04:10:55.051425-05:
      DOI: 10.1002/aoc.3957
       
  • Oxidation reactions catalysed by molybdenum(VI) complexes grafted on
           UiO-66 metal–organic framework as an elegant nanoreactor
    • Authors: Niloufar Afzali; Shahram Tangestaninejad, Majid Moghadam, Valiollah Mirkhani, Adam Mechler, Iraj Mohammadpoor-Baltork, Reihaneh Kardanpour, Farnaz Zadehahmadi
      Abstract: A heterogeneous catalyst was synthesized by immobilizing Mo(CO)3 in a UiO-66 metal–organic framework. The benzene ring of the organic linker in UiO-66 was modified via liquid-phase deposition of molybdenum hexacarbonyl, Mo(CO)6, as starting precursor to form the (arene)Mo(CO)3 species inside the framework. The structure of this catalyst was characterized using X-ray diffraction, and chemical integrity was confirmed using Fourier transform infrared and diffuse reflectance UV–visible spectroscopic methods. The metal content was analysed with inductively coupled plasma. Field emission scanning electron microscopy was used to measure particle size and N2 adsorption measurements to characterize the specific surface area. This catalytic system was efficiently applied for epoxidation of alkenes and oxidation of sulfides. The Mo-containing metal–organic framework was reused several times without any appreciable loss of its efficiency.We have developed an eco-friendly solid catalyst by immobilization of Mo complex into the framework of UiO-66 following a post-synthetic modification strategy. The benzene ring of the organic linker in UiO-66 was modified with Mo(CO)3 species. The prepared catalyst was totally characterized and efficiently applied for epoxidation of alkenes and oxidation of sulfides.
      PubDate: 2017-08-22T04:10:44.82014-05:0
      DOI: 10.1002/aoc.3958
       
  • Polystyrene-supported Pd(II)–N-heterocyclic carbene complex as a
           heterogeneous and recyclable precatalyst for cross-coupling of acyl
           chlorides with arylboronic acids
    • Authors: Barahman Movassagh; Fatemeh Hajizadeh, Elmira Mohammadi
      Abstract: Palladium-catalysed cross-coupling reaction of aroyl chlorides with arylboronic acids was achieved in the presence of polystyrene-supported palladium(II)–N-heterocyclic carbene complex, using K2CO3 in acetone–water, providing diaryl ketones in high yields. Furthermore, the heterogeneous catalyst could be reused up to four times without significant loss of activity.PS-NHC-Pd(II) was used in the Suzuki–Miyaura cross-coupling of aroyl chlorides and arylboronic acids to produce a wide range of diaryl ketones. This heterogeneous catalyst exhibited high efficiency in aqueous media under mild reaction conditions. It was recycled for four successive runs without any significant loss in its activity.
      PubDate: 2017-08-15T03:01:35.205682-05:
      DOI: 10.1002/aoc.3982
       
  • Utilization of industrial waste as a novel adsorbent: Mono/competitive
           adsorption of chromium(VI) and nickel(II) using diatomite waste modified
           by EDTA
    • Authors: Haitao Sha; Yunhai Wu, Yiang Fan
      Abstract: The adsorption of Cr(VI) and Ni(II) using ethylenediaminetetraacetic acid-modified diatomite waste (EDTA-DW) as an adsorbent in single and binary systems was investigated. The EDTA-DW was characterized using various analytical techniques, including Fourier transform infrared spectroscopy, thermogravimetric analysis, Brunauer–Emmett–Teller measurements, X-ray diffraction, scanning electron microscopy and energy-dispersive spectrometry. The adsorption experiment was conducted by varying pH, adsorbent dosage, initial concentration and temperature. In the single system, the sorption data for Cr(VI) fitted the Langmuir isotherm, but the Ni(II) adsorption data fitted well the Freundlich isotherm. The maximum sorption capacity of Cr(VI) and Ni(II) was 2.9 mg g−1 at pH = 3 and 3.64 mg g−1 at pH = 8, respectively. The kinetic data for both Cr(VI) and Ni(II) followed well the pseudo-second-order kinetic model in single and binary systems. Meanwhile, the extended Langmuir and extended Freundlich multicomponent isotherm models were found to fit the competitive adsorption data for Cr(VI) and Ni(II). In addition, in the binary system, the existence of Ni(II) hindered the adsorption of Cr(VI), but the presence of Cr(VI) enhanced the removal of Ni(II). This study provides some realistic and valid data about the usage of modified diatomite waste for the removal of metal ions.The aim was to recycle diatomite waste into a novel adsorbent. To improve adsorption capacity, EDTA was chosen to modify the diatomite waste. The physical and chemical properties of the surface of the adsorbent could be demonstrated by a series of representations. The novel adsorbent shows different adsorption capacities between single system and binary system for Cr(VI) and Ni(II).
      PubDate: 2017-08-15T03:01:31.717777-05:
      DOI: 10.1002/aoc.3977
       
  • Palladium(II) complexes bearing N-alkylpiperidoimidazolin-2-ylidene
           derivatives: Effect of alkyl chain length of ligands on catalytic activity
           
    • Authors: Sinem Çakır; Gülşah Türkmen, Hayati Türkmen
      Abstract: A series of piperidoimidazolinium salts which differ in the chain lengths (butyl, octyl, dodecyl, octadecyl) and their Pd–N-heterocyclic carbene complexes with pyridine were synthesized and characterized using elemental analysis and spectroscopic methods. The effects of these ligands on catalyst activation and the performance of the complexes were studied in Suzuki–Miyaura reactions of arylboronic acid with aryl chlorides. The complex with the ligand having the longest chain length was found to be most active. The results demonstrated that the length of the alkyl chain of the piperidoimidazolin-2-ylidene controlled the dispersion and composition of the nanoparticles and it affected the catalytic activity. The impact of alkyl chain length of piperidoimidazolin-2-ylidene on the Suzuki–Miyaura reactions of arylboronic acid with aryl halides was systematically investigated.Pd-PEPPSI-NHC complexes with various chain lengths were prepared and characterized. The catalytic activities of the complexes in Suzuki–Miyaura C–C coupling reactions were investigated and compared. The aliphatic chain length of the complexes affects the dispersion and composition of the nanoparticles.
      PubDate: 2017-08-15T02:55:48.856972-05:
      DOI: 10.1002/aoc.3969
       
  • Facile synthesis of PtSnZn nanosheet thin film at oil–water interface by
           use of organometallic complexes: An efficient catalyst for methanol
           oxidation and p-nitrophenol reduction reactions
    • Authors: Sajad Saberi Sarmoor; S. Jafar Hoseini, Roghayeh Hashemi Fath, Mahmoud Roushani, Mehrangiz Bahrami
      Abstract: PtSnZn nanosheet thin film with stable and high activity towards methanol electro-oxidation was synthesized via a simple reduction of organometallic precursors including [PtCl2(cod)] (cod = cis,cis-1,5-cyclooctadiene) and [Sn(CH3)4] complexes, in the presence of [Zn(acac)2] (acac = acetylacetonate) complex at toluene–water interface. Catalytic activities of PtSnZn nanosheets were investigated in the p-nitrophenol (p-Nip) reduction and methanol oxidation reactions. The obtained results demonstrate that PtSnZn nanosheets exhibit a good electrocatalytic performance for methanol oxidation reaction, the catalytic activity of the PtSnZn nanosheets being at least 3.5 times higher than that of Pt nanoparticle thin film. Also, the apparent rate constant obtained for p-Nip reduction with the PtSnZn nanosheets is at least 2.3 times higher than that for Pt nanoparticle thin film due to the appropriate interaction between platinum, tin and zinc metals and geometric properties of PtSnZn nanosheet thin film. Nanosheets are highly favourable for superior catalytic performances due to their geometric properties. A facile and efficient route was used to synthesize trimetallic alloy thin film at oil–water interface.A planar toluene–water interface was used as an ideal template for self-assembly of PtSnZn nanosheet thin film. The PtSnZn nanosheets are an efficient catalyst for methanol oxidation and p-nitrophenol reduction reactions.
      PubDate: 2017-08-15T02:55:38.254095-05:
      DOI: 10.1002/aoc.3979
       
  • Synthesis, characterization and photocatalytic application of
           TiO2/magnetic graphene for efficient photodegradation of crystal violet
    • Authors: Zahra Aalimohammadi Piranshahi; Mohammad Behbahani, Fatemeh Zeraatpisheh
      Abstract: A magnetized nano-photocatalyst based on TiO2/magnetic graphene was developed for efficient photodegradation of crystal violet (CV). Scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy and elemental mapping were used to characterize the prepared magnetic nano-photocatalyst. The photocatalytic activity of the synthesized magnetic nano-photocatalyst was evaluated using the decomposition of CV as a model organic pollutant under UV light irradiation. The obtained results showed that TiO2/magnetic graphene exhibited much higher photocatalytic performance than bare TiO2. Incorporation of graphene enhanced the activity of the prepared magnetic nano-photocatalyst. TiO2/magnetic graphene can be easily separated from an aqueous solution by applying an external magnetic field. Effects of pH, magnetized nano-photocatalyst dosage, UV light irradiation time, H2O2 amount and initial concentration of dye on the photodegradation efficiency were evaluated and optimized. Efficient photodegradation (>98%) of the selected dye under optimized conditions using the synthesized nano-photocatalyst under UV light irradiation was achieved in 25 min. The prepared magnetic nano-photocatalyst can be used in a wide pH range (4–10) for degradation of CV. The effects of scavengers, namely methanol (OH• scavenger), p-benzoquinone (O2•− scavenger) and disodium ethylenediaminetetraacetate (hole scavenger), on CV photodegradation were investigated.A synthesized magnetic nano-photocatalyst showed strong synergetic effect between graphene nanosheets and TiO2, which improved charge separation properties. The photocatalytic ability of the synthesized magnetic nano-photocatalyst was evaluated using degradation of crystal violet (CV) as a model organic pollutant under UV light irradiation. The efficiency of degradation of CV in the presence and absence of hydrogen peroxide was>98% after 60 and 25 min, respectively.
      PubDate: 2017-08-15T02:50:55.979628-05:
      DOI: 10.1002/aoc.3985
       
  • Dimethyltin(IV) complexes derived from hydroxamic acid and acylhydrazone
           
    • Authors: Kai Liu; Guoliang Chang, Hui Yan, Zhen Li, Min Hong, Meiju Niu
      Abstract: Two novel dimethyltin(IV) complexes, Me2SnL1(PyCOO)(MeOH) (1) and Me2SnL2 (2) (HL1 = 4-pyridinehydroxamic acid and H2L2 = 2-hydroxy-N′-[(2-hydroxy-5-chlorophenyl)methylidene]benzoylhydrazone), were synthesized and characterized using elemental analyses, Fourier transform infrared and NMR (1H, 13C) spectroscopies and single-crystal X-ray diffraction. In complex 1 the geometry around the tin atom is a six-coordinated distorted octahedral configuration, while complex 2 exhibits five-coordinated distorted trigonal bipyramid geometry. Preliminary in vitro cytotoxicity studies with two human cancer cell lines (HeLa and A549) using MTT assay show that complex 1 is more potent than complex 2. The interactions of the two complexes with calf thymus DNA and bovine serum albumin were also investigated using UV–visible absorption spectral, thermal denaturation and viscosity measurements and docking analysis. Investigations indicate that the structures of the mixed ligands play an important role in the properties of the dimethyltin(IV) complexes, and, to some extent, the antitumor activities of the complexes are partly related to interactions with DNA and some proteins in cancer cells.Two dimethyltin(IV) complexes were synthesized and characterized using some spectroscopy methods and single-crystal X-ray diffraction. In vitro cytotoxicity studies with two human cancer cell lines using MTT assay show that complex 1 is more potent than complex 2 and cisplatin. The results of the interaction of the complexes with CT-DNA and BSA indicated that the mixed ligands play an important role in the properties of the complexes. These studies could be helpful in the development of organotin complexes potential pharmaceutical application.
      PubDate: 2017-08-15T02:45:47.849464-05:
      DOI: 10.1002/aoc.3973
       
  • Metal complexes of chalcone analogue: Synthesis, characterization, DNA
           binding, molecular docking and antimicrobial evaluation
    • Authors: Faten M. Atlam; Marwa N. El-Nahass, Eman A. Bakr, Tarek A. Fayed
      Abstract: A novel chalcone, namely 5-(4-(dimethylamino)phenyl)-1-(thiophen-2-yl)penta-2,4-dien-1-one, DMATP, and its complexes with nickel(II), vanadium(III), palladium(II) and platinum(II) metal ions were synthesized and characterized using a set of chemical and spectroscopic tools including elemental analysis, electrical conductance, magnetic susceptibility and spectral techniques. The interactions of the synthesized chalcone and its metal complexes with DNA were studied using steady-state absorption and emission techniques as well as viscosity and electrochemical measurements. The obtained results confirm DNA intercalation. Additionally, theoretical studies were performed for all the investigated compounds using DFT/B3LYP calculations. The optimized geometries are found to be in good agreement with the suggested experimental structures. The bond lengths, bond angles, chemical reactivity, energy components, binding energy and dipole moment were evaluated. Also, theoretical infrared intensities and thermodynamic parameters for all compounds were calculated. Molecular docking calculations show that the Ni(II) complex exhibits the highest DNA binding activity, which agrees well with the experimental results. Finally, the compounds were screened for antimicrobial activity using several microorganisms.
      PubDate: 2017-08-11T04:42:33.180821-05:
      DOI: 10.1002/aoc.3951
       
  • Synthesis, characterization and application of alumina/ vanadium pentoxide
           nanocomposit by sol–gel method
    • Authors: Hassan Hassani; Batol Zakerinasab, Hoda Hossien Poor
      Abstract: In this work, we report the preparation of Al2O3/V2O5 nanocomposit using vanadium and aluminum nitrate by sol–gel method. Characterization of nanocomposit was carried out by powder X-ray diffractometry (XRD), Fourier transform infrared (FT-IR), scanning electron microscopy (SEM), Energy-Dispersive X-ray (EDX) and UV spectroscopy. Then, applicability of the synthesized nanocomposit was tested as a nanocatalyst for the synthesis of diindolyl oxindole derivatives, an important class of potentially bioactive compounds. The products were obtained in good to high yields from one-pot three-component condensation of isatin with indole. Also, this nanocatalyst has been reused several times, without observable loss of activity.In this work, we report the preparation of Al2O3/V2O5 nanocomposit by sol–gel method. Also, Al2O3/ V2O5 nanocomposit was used for the synthesis of diindolyl oxindole derivatives in good to high yields.
      PubDate: 2017-08-11T04:41:06.059051-05:
      DOI: 10.1002/aoc.3945
       
  • Facile Chemoselective synthesis of
           2-(2-(Methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acids and
           3H,3’H-Spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives
    • Authors: Neda Firoozi; Zohreh Roshan, Mohammad Reza Mohammadizadeh
      Abstract: Oxidation of some derivatives of 4b,9b–dihydroxyindeno[1,2-b]benzofuran-10-one have been investigated in detail using lead(IV) acetate in acetic acid under reflux conditions and periodic acid in aqueous ethanol at room temperature. We realized that during the first 5–15 minutes of the oxidation reactions in lead(IV) acetate/acetic acid system, 3H,3’H-spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives have been synthesized chemo selectively, while, if the reaction mixtures stirred for additional 3 hours, the main products would be 2-(2-(Methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acids. Moreover, room temperature oxidation of 4b,9b–dihydroxyindeno[1,2-b]benzofuran-10-ones by periodic acid (H5IO6), leads to the formation of 3H,3’H-spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione derivatives in good to excellent yields.3H,3'H-Spiro[benzofuran-2,1'-isobenzofuran]-3,3'-diones were chemoselectively obtained as the major products during first 15 minutes of the oxidation reactions of 4b,9b-dihydroxyindeno[1,2-b]benzofuran-10-ones with lead(IV) acetate in acetic acid. Interestingly, if the oxidation reactions were continued for 3 hours, 2-(2-(methoxycarbonyl)-3-oxo-2,3-dihydrobenzofuran-2-yl)benzoic acid derivatives would be obtained in moderate to good yields. Additionally, oxidation of dihydroxyindeno[1,2-b]benzofuran-10-ones with periodic acid in aqueous media resulted in the formation of 3H,3'H-spiro[benzofuran-2,1'-isobenzofuran]-3,3'-diones.
      PubDate: 2017-08-11T04:36:42.911124-05:
      DOI: 10.1002/aoc.3963
       
  • Syntheses, silylation, characterization, and antimicrobial and
           antifertility activities of organoboron derivatives of some bioactive
           monofunctional bidentate semicarbazones
    • Authors: Jyoti Bhomia; Jyoti Sharma, Rucha Lakhne, Rachna Sharma, R.S. Gupta, Ram Avatar Sharma, Yashpal Singh
      Abstract: Some new mononuclear organoboron derivatives of the type PhBL1–5(OH) (1a–1e) were synthesized by the reaction of PhB(OH)2 and LH (LH = OC(NH2)NH:NC(CH3)4C6H4R, where R = H (L1H); CH3(L2H); OCH3(L3H); Cl (L4H); Br (L5H)) in 1:1 molar ratio in refluxing tetrahydrofuran (THF). This was followed by the reactions of PhBL1–5(OH) with NH(SiMe3)2 in 2:1 molar ratio in THF to yield new heterodinuclear derivatives of the type PhBL1–5(OSiMe3) (2a–2e). All these newly synthesized complexes were characterized using elemental analyses and their probable structure was proposed on the basis of infrared, 1H NMR, 13C NMR, 11B NMR and 29Si NMR spectral data and mass spectrometry. Semicarbazone ligands and their corresponding mono- and heterodinuclear boron derivatives were screened against pathogenic bacteria (E. coli and P. aeruginosa) and fungi (A. niger and P. peniculosum) to examine their antimicrobial activities. Representative compounds of each series of mono- and heterodinuclear boron derivatives and a ligand were screened for their antifertility activity on male adult Wistar rats.Antimicrobial and antifertility activities of semicarbazones and their corresponding mono- and heterodinuclear boron derivatives have been investigated with a view to examining their potential as drugs.
      PubDate: 2017-08-11T04:36:06.328177-05:
      DOI: 10.1002/aoc.3983
       
  • Ni(II)-Adenine complex coated Fe3O4 nanoparticles as high reusable
           nanocatalyst for the synthesis of polyhydroquinoline derivatives and
           oxidation reactions
    • Authors: Taiebeh Tamoradi; Mohammad Ghadermazi, Arash Ghorbani-Choghamarani
      Abstract: In the present study, Fe3O4 nanoparticles were prepared via simple and versatile procedure. Then, a novel and green catalyst was synthesized by the immobilization of Ni on Fe3O4 nanoparticles coated with adenine. The activity of this nanostructure compound was examined for the oxidation of sulfides, oxidative coupling of thiols and synthesis of polyhydroquinolines. The prepared catalyst was characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma optical emission spectroscopy (ICP-OES), X-ray Diffraction (XRD), thermal gravimetric analysis (TGA), and vibrating sample magnetometer (VSM) measurements. This organometallic catalyst was recovered by the assistance of an external magnetic field from the reaction mixture and reused for seven continuous cycles without noticeable change in its catalytic activity.Ni(II)-Adenine complex coated Fe3O4 nanoparticles has been prepared and characterized with different techniques. This nano structural compound applied as an efficient catalyst for the oxidation of sulfides, oxidative coupling of thiols and synthesis of polyhydroquinolines.
      PubDate: 2017-08-08T05:31:05.285717-05:
      DOI: 10.1002/aoc.3974
       
  • Uniformly dispersed copper nanoparticles onto the modified magnetically
           recoverable nanocatalyst for aqueous synthesis of primary amides
    • Authors: Fariborz Ziaee; Mostafa Gholizadeh, Seyed Mohammad Seyedi
      Abstract: Magnetically recoverable and environmentally friendly Cu-based heterogeneous catalyst has been synthesized for the one-pot conversion of aldehydes to their corresponding primary amides. The Fe3O4@SiO2 nanocomposites were prepared by synthesis of Fe3O4 magnetic nanoparticles (MNPs) which was then coated with a silica shell via Stöber method. Bi-functional cysteine amino acid was covalently bonded onto the siliceous shell of nanocatalyst. The CuII ions were then loaded onto the modified surface of nanocatalyst. Finally, uniformly dispersed copper nanoparticles were achieved by reduction of CuII ions with NaBH4. Amidation reaction of aryl halides with electron-withdrawing or electron-donating groups and hydroxylamine hydrochloride catalyzed with Fe3O4@SiO2@Cysteine-copper (FSC-Cu) MNPs in aqueous condition gave an excellent yield of products. The FSC-Cu MNPs could be easily isolated from the reaction mixture with an external magnet and reused at least 8 times without significant loss in activity.Magnetically recoverable and environmentally friendly Cu-based heterogeneous catalyst has been synthesized for the one-pot conversion of aldehydes to their corresponding primary amides. Cysteine was used as a ligand for modification of silica coated magnetic nanoparticles which used for generation of Cu NPs. The mild reaction conditions, broad substrate scope make FSC-Cu MNPs efficient and environmentally friendly for the synthesis of primary amides.
      PubDate: 2017-08-01T23:12:24.996548-05:
      DOI: 10.1002/aoc.3925
       
  • Reaction of dimethylplatinum(II) complexes with PhCH2CH2Br: Comparative
           reactivity with CH3CH2Br and PhCH2Br and synthesis of Pt(IV) complexes
    • Authors: Mozhgan Samandar Sangari; Mehdi Rashidi, S. Masoud Nabavizadeh, Banafshe Askari, Fatemeh Niroomand Hosseini
      Abstract: Oxidative addition of 2-phenylethylbromide (PhCH2CH2Br) to dimethylplatinum(II) complexes [PtMe2(NN)] (1a, NN = 2,2′-bipyridine (bpy); 1b, NN = 1,10-phenanthroline (phen)) afforded the new organoplatinum(IV) complexes [PtMe2(Br)(PhCH2CH2)(bpy)], as a mixture of trans (2a) and cis (3a) isomers, and [PtMe2(Br)(PhCH2CH2)(phen)], as a mixture of trans (2b) and cis (3b) isomers, respectively. The new Pt(IV) complexes were readily characterized using multinuclear (1H and 13C) NMR spectroscopy and elemental microanalysis. The crystal structure of 2a was further determined using X-ray crystallography indicating an octahedral geometry around the platinum centre. A comparison of reactivity of RCH2Br reagents (R = CH3, Ph or PhCH2) in their oxidative addition reactions with complex 1a, with an emphasis on the effects of the R groups of alkyl halides, was also conducted using density functional theory.Oxidative addition of 2-phenylethylbromide to dimethylplatinum(II) complexes afforded new organoplatinum(IV) complexes as a mixture of trans and cis addition products.
      PubDate: 2017-07-28T06:28:56.77112-05:0
      DOI: 10.1002/aoc.3954
       
  • A ferrocene-containing porous organic polymer linked by tetrahedral
           silicon-centered units for gas sorption
    • Authors: Qingyu Ma; Yipeng Qi, Jianquan Li, Weiguo Wang, Xuejiao Sun
      Abstract: A novel ferrocene-containing porous organic polymer (FPOP) has been prepared by Sonogashira-Hagihara coupling reaction of 1,1′-dibromoferrocene and tetrakis(4-ethynylphenyl)silane. Compared with other polymers, the resulting polymer possesses excellent thermal stability with the decomposition temperature of 415°C and high porosity with Brunauer–Emmett–Teller (BET) surface area of 542 m2 g−1 as measured by nitrogen adsorption-desoprtion isotherm at 77 K. For applications, it shows moderate carbon dioxide uptakes of up to 1.42 mmol g−1 (6.26 wt%) at 273 K/1.0 bar and 0.82 mmol g−1 (3.62 wt%) at 298 K/1.0 bar, and hydrogen capacity of up to 0.45 mmol g−1 (0.91 wt%) at 77 K/1.0 bar, indicating that FPOP might be utilized as a promising candidate for storing carbon dioxide and hydrogen. Although FPOP possesses lower porosity than many porous polymers, the gas capacities are higher or comparable to them, thereby revealing that the incorporation of ferrocene units into the network is an effective strategy to enhance the affinity between the framework and gas.A novel ferrocene-containing porous organic polymer (FPOP) constructed from 1,1′-dibromoferrocene and tetrakis(4-ethynylphenyl)silane exhibits excellent thermal stability, high porosity and can be utilized as a promising candidate for storing CO2 and H2.
      PubDate: 2017-07-27T01:56:27.836705-05:
      DOI: 10.1002/aoc.3935
       
  • 2-Arylation/alkylation of benzothiazoles using superparamagneticgraphene
           oxide-Fe3O4 hybrid material as a heterogeneous catalystwith diisopropyl
           azodicarboxylate (DIAD) as an oxidant
    • Authors: Dariush Khalili; Elham Etemadi-Davan, Ali Reza Banazadeh
      Abstract: In this report, we introduced Graphene oxide-iron oxide (GO-Fe3O4) nanocomposites as a heterogeneous catalyst for arylation/alkylation of benzothiazoles with aldehydes and benzylic alcohols in the presence of diisopropyl azodicarboxylate (DIAD) as an oxidant which exclusively produced 2-aryl (alkyl)-1H–benzothizoles in moderate to excellent yields. The absence of precious metals and toxic solvent, easy product isolation, and recyclability of the GO-Fe3O4 with no loss of activity are notable advantages of this method.We introduced Graphene oxide-iron oxide (GO-Fe3O4) nanocomposites as a heterogeneous catalyst for arylation/alkylation of benzothiazoles with aldehydes and benzylic alcohols in the presence of diisopropyl azodicarboxylate (DIAD) as an oxidant which exclusively produced 2-aryl (alkyl)-1H–benzothizoles in moderate to excellent yields.
      PubDate: 2017-07-27T01:55:48.269882-05:
      DOI: 10.1002/aoc.3971
       
  • Cross-coupling reactions using porous multipod Cu2O microcrystals as
           recoverable catalyst in aqueous media
    • Authors: Lin Tang; Chaoting Wu, Qiyan Hu, Qian Li, Wu Zhang
      Abstract: Porous multipod Cu2O microcrystals were found to be an efficient, highly recyclable and eco-friendly catalyst for the cross-coupling reactions of aryl halides and terminal alkynes with high yields in aqueous media. Noteworthy, the Cu2O catalyst can be reused for several times without significant decrease in catalytic activity.Porous multipod Cu2O microcrystals were found to be an efficient, highly recyclable and eco-friendly catalyst for the cross-coupling reactions of aryl halides and terminal alkynes with high yields in aqueous media.
      PubDate: 2017-07-27T01:50:45.257401-05:
      DOI: 10.1002/aoc.3980
       
  • CuO nanoparticles supported on three-dimensional nitrogen-doped graphene
           
    • Authors: Seyed Ghorban Hosseini; Zahra Khodadadipoor, Mojtaba Mahyari
      Abstract: In the present work, CuO nanoparticles grown on three-dimensional nitrogen-doped graphene-based frameworks (CuO@3D-(N)GFs) were synthesized using a two-step method. After the synthesis of three-dimensional nitrogen-doped graphene, CuO nanoparticles were deposited on it, by adding cupric acetate followed by thermal treatment. Different analysis methods were used to characterize the products. The as-prepared nanocomposite was used as a promising catalyst for thermal decomposition of ammonium perchlorate (AP) as one of the most common oxidizer in composite propellants. Differential scanning calorimetry (DSC) and thermogravimetry analysis (TGA) techniques were used to investigate the thermal decomposition of ammonium perchlorate. According to the DSC/TGA, high temperature decomposition of AP decreased to 111 °C in the presence of 4% CuO@3D-(N)GFs and the total heat release (ΔH) from decomposition of AP increased to 1893 J g−1 which is much more than 590 J g−1 for pure AP.CuO nanoparticles grown on three-dimensional nitrogen-doped graphene based-frameworks (CuONPs@3D-(N)GFs) were found to be an efficient stable catalyst for the thermal decomposition of ammonium perchlorate.
      PubDate: 2017-07-27T01:45:50.43001-05:0
      DOI: 10.1002/aoc.3959
       
  • Graphene-mesoporous anatase TiO2 nanocomposite: A highly efficient and
           recyclable heterogeneous catalyst for one-pot multicomponent synthesis of
           benzodiazepine derivatives
    • Authors: Mohd Shoeb; Mohammad Mobin, Abad Ali, Shamsuz Zaman, Alim H. Naqvi
      Abstract: The potential to bias chemical reaction pathways is a significant goal for physicists and material researchers to design revolutionary materials. Recently, two-dimensional materials have appeared as a promising candidate for exploring novel catalyst activity in organic reaction. In this context, herein we report an easy and efficient synthesis of substituted benzodiazepines in high yields through the graphene-based mesoporous TiO2 nanocomposite (Gr@TiO2 NCs) catalyst. To validate the merits of the Gr@TiO2 NCs as a catalyst, we have also designed TiO2 nanoparticle (NPs) under similar conditions. Successful comprehension realization of Gr@TiO2 NCs and TiO2 NPs were concluded from the XRD, SEM, HR-TEM, EDS elemental mapping, FT-IR, Raman, UV–Vis and TGA analysis. Gr@TiO2 NCs has the propitious catalyst performance (~98%) over the TiO2 NPs (~77%), which could be scrutinized in terms of graphene support toward the TiO2 NPs and enable the large contact area between graphene and TiO2 NPs. Incorporated graphene maintaining TiO2 as a catalytically active and attracting electron to site isolation, as well as protecting TiO2 from oxidative degradation during the reaction. Moreover, the role of graphene is suggested to prolonged reaction duration, yield and unaltered throughout the reaction because of the π-π interaction between graphene and TiO2 NPs. Additionally, the catalyst is recycled by filtration and reprocessed six times without having a significant loss in its catalytic activity.We have successfully synthesized graphene bonded and mesoporous anatase TiO2 NPs through an ex-situ hybridization strategy. Gr@TiO2 NCs play a role in the reaction mechanism for coupling of o-phenylenediamine, dimedone, and aldehydes so as to synthesize benzodiazepine derivatives.
      PubDate: 2017-07-27T01:40:51.832524-05:
      DOI: 10.1002/aoc.3961
       
  • Synthesis of graphene oxide supported copper–cobalt ferrite material
           functionalized by arginine amino acid as a new high–performance catalyst
           
    • Authors: Rahim Ghadari; Hassan Namazi, Mohammad Aghazadeh
      Abstract: A novel Cu0.5Co0.5Fe2O4@Arg–GO catalytic system was successfully prepared by immobilization of copper substituted cobalt ferrite nanoparticles on arginine–grafted graphene oxide nanosheets, in which ferrite moiety acts as an oxidation catalyst and arginine has the role of base catalyst. Also, arginine amino acid was used to modify the surface of graphene oxide nanosheets which the prepared support can improve dispersion and uniform loading of nanoparticles. The prepared nanocomposite was characterized by flame atomic absorption spectroscopy (FAAS), inductively coupled plasma optical emission spectrometer (ICP–OES), energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT–IR), ultraviolet–visible spectroscopy (UV–vis), Raman spectroscopy, thermogravimetric analysis (TGA), x–ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) analysis. The prepared Cu0.5Co0.5Fe2O4@Arg–GO nanocomposite was used as an efficient catalyst for one–pot tandem oxidative synthesis of 2–phenylbenzimidazole derivatives in good yields.Arginine amino acid was attached to the surface of graphene oxide nanosheets to produce a green support for immobilization of copper substituted cobalt ferrite nanoparticles. The prepared catalyst was used for the one-pot tandem oxidative cyclization of primary alcohols with o-phenylenediamines to produce benzimidazoles under aerobic oxidation conditions, with efficient activity and reusability.
      PubDate: 2017-07-27T01:35:51.360482-05:
      DOI: 10.1002/aoc.3965
       
  • Green route for selective gram-scale oxidation of sulfides using
           tungstate/triazine-based ionic liquid immobilized on magnetic
           nanoparticles as a phase-transfer heterogeneous catalyst
    • Authors: Seyed Hassan Hosseini; Maryam Tavakolizadeh, Nasrin Zohreh, Rouhollah Soleyman
      Abstract: Tungstate ions were successfully loaded onto triazine-based ionic liquid-functionalized magnetic nanoparticles through an anion exchange process. The use of triazine core for creating ionic liquid led to the immobilization of high amounts of WO42−. The resulting catalyst showed high activity and selectivity in the oxidation of sulfides to sulfoxides with H2O2 as a green oxidant at room temperature. In addition, due to the presence of ammonium groups in the catalyst structure, water dispersibility of the catalyst was increased. More important, the catalyst was magnetically recovered and reused for up to six runs without any marked decrease of activity and selectivity. Finally, easy gram-scale oxidation of methylphenyl sulfide as well as fast separation of catalyst and product makes the protocol economical and industrially applicable.Simple preparation of tungstate/triazine-based ionic liquid immobilized on magnetic nanoparticles is provided as a phase-transfer catalyst for gram-scale selective oxidation of sulfides using 0.4 mol% catalyst loading. H2O and H2O2 used as green solvent and oxidant. Reusability of catalyst is up to 6 subsequent runs without significant loss of activity or leaching.
      PubDate: 2017-07-27T01:31:35.686901-05:
      DOI: 10.1002/aoc.3953
       
  • Molecular structure, molecular docking, thermal, spectroscopic and
           biological activity studies of bis-Schiff base ligand and its metal
           complexes
    • Authors: Ehab M. Zayed; Ahmed M.M. Hindy, Gehad G. Mohamed
      Abstract: Coordination compounds of Fe(III), Zn(II), Ni(II), Co(II), Cu(II), Cd(II) and Mn(II) ions were synthesized from the ligand [4,4′-((((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))bis(azanylylidene))diphenol]ethane (H2L) derived from the condensation of bisaldehyde and 4-aminophenol. Microanalysis, magnetic susceptibility, infrared, 1H NMR and mass spectroscopies, molar conductance, X ray powder diffraction and thermal analysis were used to confirm the structure of the synthesized chelates. According to the data obtained, the composition of the 1:1 metal ion–bis-Schiff base ligand was found to be [M(H2L)(H2O)2]Cln (M = Zn(II), Ni(II), Co(II), Cu(II), Cd(II) and Mn(II), n = 2; Fe(III), n = 3). Magnetic susceptibility measurements and reflectance spectra suggested an octahedral geometry for the complexes. Central metals ions and bis-Schiff base coordinated together via O2 and N2 donor sites which as evident from infrared spectra. The Gaussian09 program was applied to optimize the structural formula for the investigated Schiff base ligand. The energy gaps and other important theoretical parameters were calculated applying the DFT/B3LYP method. Molecular docking using AutoDock tools was utilized to explain the experimental behaviour of the Schiff base ligand towards proteins of Bacillus subtilis (5 h67), Escherichia coli (3 t88), Proteus vulgaris (5i39) and Staphylococcus aureus (3ty7) microorganisms through theoretical calculations. The docked protein receptors were investigated and the energies of hydrogen bonding were calculated. These complexes were then subjected to in vitro antibacterial studies against several organisms, both Gram negative (P. vulgaris and E. coli) and Gram positive (S. pyogones and B. subtilis). The ligand and metal complexes exhibited good microbial activity against the Gram-positive and Gram-negative bacteria.Optimized structure, and HOMO and LUMO patterns of bis-Schiff base ligand.
      PubDate: 2017-07-27T01:31:19.896239-05:
      DOI: 10.1002/aoc.3952
       
  • Hydrogenation of nitroarenes catalyzed by a dipalladium complex
    • Authors: Ming-Uei Hung; Shu-Ting Yang, Mani Ramanathan, Shiuh-Tzung Liu
      Abstract: A dipalladium complex [Pd2(L)Cl2](PF6)2 (2), via the substitution of (PhCN)2PdCl2 with 5-phenyl-2,8-bis(6′-bipyridinyl)-1,9,10-anthyridine (L) followed by the anion exchange, was found to be a good pre-catalyst for the reduction of nitroarenes to yield the corresponding anilines under atmospheric pressure of hydrogen in methanol. This method provides a straightforward access to a diverse array of functionalized anilines, exhibiting a possible application in synthetic chemistry. The catalytic activity of this complex is enhanced by the di-metallic system via the synergistic effect.A dipalladium complex resulting from complexation of [Pd(CH3CN)2Cl2] with 5-phenyl-2,8-bis(6′-bipyridinyl)-1,9,10-anthyridine has found to be a good catalyst for reduction of nitroarenes into the corresponding anilines under atmospheric pressure of hydrogen, presumably due to the cooperative interaction between metal ions.
      PubDate: 2017-07-27T01:26:13.296188-05:
      DOI: 10.1002/aoc.3976
       
  • Fe3O4@S-ABENZ@VO: Magnetically separable nanocatalyst for the efficient,
           
    • Authors: Somaieh Rezaei; Arash Ghorbani-Choghamarani, Rashid Badri, Ahmad Nikseresht
      Abstract: Oxovanadium(IV) immobilized on Fe3O4@S-ABEN is reported as a highly efficient nanocatalyst for the oxidation of sulfides and oxidative coupling of thiols (using H2O2 as green oxidant), the products of which are obtained in high to excellent yields. The products can be separated by a simple extraction with organic solvent and the catalyst is highly efficient, especially in terms of selectivity of desired product. The catalytic system can be recycled and reused without significant loss of catalytic activity.Fe3O4@S-ABEN has been prepared as new nanocatalyst and characterized by different techniques. This nano structural compound applied for the oxidation of sulfides and oxidative coupling of thiols using H2O2, as green oxidant.
      PubDate: 2017-07-27T01:22:01.637843-05:
      DOI: 10.1002/aoc.3948
       
  • Copper(I) complex covalently anchored on graphene oxide as an efficient
           and recyclable catalyst for Sonogashira reaction
    • Authors: Roghayeh Hashemi Fath; S. Jafar Hoseini
      Abstract: In this study, the organosilane-functionalized graphene oxide as a stabilizer was prepared by a facile one-step silylation approach. [Cu(PPh3)3Cl] complex was successfully immobilized onto the graphene oxide surface through coordination interaction with organosilane ligand spacers. The supported catalyst showed enhanced catalytic performance toward Sonogashira reaction of aryl halides with phenylacetylene in water solvent compared with the homogeneous analogues, and it could be readily recycled and reused several times without discernible loss of its activity.Copper(I) complex was covalently anchored onto the graphene oxide surface through coordination interaction by employing (3-aminopropyl)triethoxysilane ligand spacers and were used as efficient catalyst in the Sonogashira reaction.
      PubDate: 2017-07-21T06:01:09.871242-05:
      DOI: 10.1002/aoc.3964
       
  • A comparative study on the catalytic performance of heme and non-heme
           catalysts: Metal porphyrins versus metal Schiff bases
    • Authors: Atefeh Talaeizadeh; Mahdi Tofighi, Saeed Zakavi
      Abstract: Catalytic activity and oxidative stability of a series of iron and manganese porphyrins with 2-chlorophenyl, phenyl and 4-methoxyphenyl at the meso positions and metallosalens (Mn- and Fe-salens) including N,N′-bis(salicylidene)ethylenediamine, N,N′-bis(5- chlorosalicylidene)ethylenediamine and N,N′-bis(2,4-dihydroxysalicylidene)ethylenediamine for the oxidation of olefins with tetra-n-butylammonium periodate (TBAP) and tetra-n-butyl-ammonium Oxone (TBAO) have been investigated and compared. Although the metalloporphyrins showed an increased catalytic activity relative to the Schiff base complexes, the former provided no significant catalytic advantage over the latter. Also, a comparable or slightly higher oxidative stability was observed for the Schiff base complexes under the reaction conditions. Furthermore, in spite of large difference between the oxidizing ability of TBAO and TBAP, similar patterns were observed for the order of catalytic activity and oxidative stability of the used heme and non-heme catalysts. The introduction of a methyl group at the ɑ position of styrene led to an increase in its reactivity, indicating the dominance of electronic effects over the steric ones in these catalytic systems.The oxidation of olefins with tetra-butylammonium periodate and Oxone was conducted in the presence of the manganese and iron complexes of a series of porphyrins and Schiff bases to compare their relative catalytic activity and oxidative stability.
      PubDate: 2017-07-21T06:00:48.602452-05:
      DOI: 10.1002/aoc.3967
       
  • Amino acid ionic liquid-based titanomagnetite nanoparticles: An efficient
           and green nanocatalyst for the synthesis of
           1,4-dihydropyrano[2,3-c]pyrazoles
    • Authors: Davood Azarifar; Omolbanin Badalkhani, Younes Abbasi
      Abstract: The amino acid ionic liquid tetrabutylammonium asparaginate (TBAAsp) was immobilized on titanomagnetite (Fe3−xTixO4) nanoparticles in a facile one-pot process using an organosilane compound (TMSP) as spacer. The modified Fe3−xTixO4@TMSP@TBAAsp magnetic nanoparticles were characterized using Fourier transform spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, vibrating sample magnetometry and thermogravimetric analysis. The resulting analytical data clearly verified the successful immobilization of the ionic liquid on the magnetic substrate. The magnetic ionic liquid-based nanoparticles exhibited high catalytic activity in the synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives via a one-pot three-component reaction under mild reaction conditions. The catalyst was easily recycled and reused for at least six runs without any considerable loss of activity.Tetrabutylammonium asparaginate (TBAAsp) ionic liquid-functionalized titanomagnetite (Fe3−xTixO4@TMSP@TBAAsp) nanoparticles as an efficient and recyclable heterogeneous nanocatalyst were synthesized via a simple procedure for the first time. The prepared catalyst was fully characterized. Catalytic activity of this green catalyst was explored for one-pot three-component synthesis of dihydropyrano[2,3-c]pyrazoles under solvent-free conditions.
      PubDate: 2017-07-21T05:56:38.527075-05:
      DOI: 10.1002/aoc.3949
       
  • Synthesis and spectroscopic characterizations of Cu(II) complexes with
           novel 15-membered N4 macrocyclic ligand and their utility to obtain CuO
           nanostructures for efficient degradation of dyes
    • Authors: Abdel Majid A. Adam; A. Alhadhrami, Hosam A. Saad, Moamen S. Refat
      Abstract: This paper describes synthesis, characterization and application of a series of Cu(II) complexes with a novel 3-thioxo-[1,2,4,5]tetrazocane-6,8-dione (N4) macrocyclic ligand. The complexes were characterized by physicochemical and spectroscopic techniques, such as UV–visible and IR spectroscopies, molar conductance, magnetic susceptibility measurements, and elemental analysis. The data suggest that the mononuclear Cu(II) complexes have a metal-to-ligand mole ratio of 1:1 and that the Cu(II) ions are coordinated with the four nitrogen atoms inside the N4 macrocyclic ring. The experimental anisotropic g-values indicate that the chloro, nitrato, acetate, and perchlorato complexes have six-coordinate distorted octahedral behavior, whereas the sulfato complex has five-coordinate square-pyramidal geometry. A simple and nontoxic method for preparation of CuO nanoparticles based upon the thermal decomposition of the synthesized Cu(II) complexes has been explored. Finally, the degradation of Rhodamine 6G dye by the catalytic performance of nano-sized CuO material has been evaluated.A novel 15-membered N4 macrocyclic ligand was prepared. The direct thermal decomposition of the nitrato Cu(II) complex with this ligand leads to a CuO material with an unusual ice shovel-like-shaped morphology involving a highly organized nanoscale structure.
      PubDate: 2017-07-21T05:56:18.932548-05:
      DOI: 10.1002/aoc.3950
       
  • Phosphated tungstate: An efficient new solid phosphoric acid catalyst for
           the synthesis of heterocyclic nitrones
    • Authors: Alireza Banan; Hassan Valizadeh, Akbar Heydari, Abolghasem Moghimi
      Abstract: Phosphated tungstate as a new, reusable and efficient solid phosphoric acid catalyst was synthesized and used to promote the reaction of diaminoglyoxime with various aromatic aldehydes. The prepared phosphated tungstate was characterized using various techniques including X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy and thermal analysis. A wide variety of heterocyclic nitrones were obtained under mild reaction conditions and in high yields by using the prepared catalyst.Phosphated tungstate as a new, reusable and efficient solid phosphoric acid catalyst was synthesized, and to promote the reaction of diaminoglyoxime with various aromatic aldehydes. A wide variety of heterocyclic nitrones were obtained under mild reaction conditions and in high yields.
      PubDate: 2017-07-21T05:50:45.472423-05:
      DOI: 10.1002/aoc.3944
       
  • Sulfuric acid heterogenized on magnetic Fe3O4 nanoparticles: A new and
           efficient magnetically reusable catalyst for condensation reactions
    • Authors: Lotfi Shiri; Setare Zarei, Mosstafa Kazemi, Davood Sheikh
      Abstract: Immobilized sulfuric acid on magnetic Fe3O4 nanoparticles (Fe3O4 MNPs-OSO3H) as a new solid acid nanocomposite was successfully synthesized and its catalytic activity in a series of condensation reactions was studied. High catalytic activity, simple separation from reaction mixture by an external magnet and good reusability are several eco-friendly advantages of this catalytic system. It is noteworthy that this catalytic system is applicable to a wide range of spectrum of aromatic aldehydes, and the desired products were obtained in good to excellent yields under mild conditions. The use of ecofriendly solvents makes also this synthetic protocol ideal and fascinating from the environmental point of view.Sulfuric acid heterogenized on magnetic Fe3O4 nanoparticles (Fe3O4 MNPs-OSO3H) was found to be a novel, eco-friendly and versatile magnetically recoverable catalyst for the condensation reactions.
      PubDate: 2017-07-21T05:45:50.423418-05:
      DOI: 10.1002/aoc.3938
       
  • Anti-proliferative activity of newly synthesized cd(II), cu(II),
           Zn(II),Ni(II), co(II), VO(II), and Mn(II) complexes of
           2-((4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)methylene)
           hydrazinecarbothioamide on three human cancer cells
    • Authors: Mohamad M.E. Shakdofa; Hanan A. Mousa, Ahmed M.A. Elseidy, Ammar A. Labib, Mamdouh M. Ali, Amira S. Abd-El-All
      Abstract: Thiosemicarbazone ligand, 2-((4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)methylene) hydrazinecarbothioamide and its Cd(II), Cu(II), Zn(II), Ni(II), Co(II), VO(II), and Mn(II) complexes have been prepared and characterized by various spectroscopic and analytical techniques. Complexes molar conductance measurements displayed that all complexes (2–8) are non-electrolyte. With general composition [M(H3L)(CH3COO)2H2O].nH2O, where M = Cd(II), Cu(II), Zn(II), Ni(II), Co(II) and Mn(II) while complex (8) has [VO(H3L)(SO4)H2O].2H2O formula. Based on analytical and spectral measurements, the octahedral or distorted octahedral geometries suggested for complexes. Ligand and complexes anti-proliferative activities were assessed against three various human tumor cell lines including breast cancer (MCF-7), liver cancer (HepG2) and lung cancer (A549) using SRB fluorometric assay and cis-platin as positive control. The anti-proliferative activity result indicated that the ligand and its complexes have considerable anti-proliferative activity analogous to that of ordinarily utilized anti-cancer drug (cis-platin). They do their anti-cancer activities by modifying free radical's generation via raising the superoxide dismutase activity and depletion of intracellular reduced glutathione level, catalase, glutathione peroxidase activities, escorted by highly generation of hydrogen peroxide, nitric oxide and other free radicals leading to tumor cells death, as monitoring by decreasing the protein and nucleic acids synthesis.Cd(II), Cu(II), Zn(II), Ni(II), Co(II), VO(II), and Mn(II) complexes of 2-((4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl) methylene) hydrazinecarbothioamide have considerable anti-proliferative activity against human breast cancer (MCF-7); human liver cancer (HepG2) and human lung cancer (A549) analogous to the activity of ordinarily utilized anticancer drug (cisplatin).
      PubDate: 2017-07-21T05:40:25.436325-05:
      DOI: 10.1002/aoc.3936
       
  • Synthesis, characterization and computational study of CuI nanoparticles
           immobilized on modified poly (styrene-co-maleic anhydride) as a green,
           efficient and recyclable heterogeneous catalyst in the synthesis of
           1,4-disubstituted 1,2,3-triazoles via click reaction
    • Authors: Fatemeh Ebrahimpour-Malamir; Tayebeh Hosseinnejad, Razieh Mirsafaei, Majid M. Heravi
      Abstract: Poly (styrene-co-maleic anhydride) (SMA) was modified by reactionwith4-amino-2-methyl-10H-thiene [2,3-b][1,5]-benzodiazepine (ATD) hydrochloride, providing an imide with the appropriate sites for the coordination of Cu(I)ions. This modified SMA was reacted with CuI to obtain immobilized Cu(I) NPs. This Cu(I) NPs (CuI/SMI-TD) was fully characterized by conventional techniques such as FT-IR, NMR, SEM, TEM, EDAX and ICP-AES analysis. The SEM and TEM images clearly showed CuI NPs as spherical shapes and the size of particles is 30-60 nm. Moreover, a quantitative description for experimental features of CuI/SMI-TD was presented via computational assessment for the interactions between copper metal ions and coordination sites of SMI-TD ligand. The catalytic activity of this new catalyst was examined in the regioselective synthesis of 1,4-disubstituted-1,2,3 triazoles in a classical copper-catalyzed reaction a so-called click reaction. The catalyst showed highly efficient catalytic activity, excellent reusability, high yield and more importantly excellent, regioselectivity. The catalyst was recoverable through simple filtration and can be reused at least five times without significant loss of catalytic activity. The heterogeneous nature of the catalyst was confirmed based on the hot filtration test and ICP-AES analysis.A novel heterogeneous catalyst based on copper (I) supported on modified SMA has been synthesized and characterized. This catalyst exhibits excellent catalytic activities in synthesis of 1,4-disubstituted 1,2,3-triazoles via click reaction.
      PubDate: 2017-07-21T05:31:12.540269-05:
      DOI: 10.1002/aoc.3913
       
  • Three Arene-Ru(II) compounds of 2-halogen-5-aminopyridine: Synthesis,
           characterization, and cytotoxicity
    • Authors: Xiao-Wei Yan; Yong-Rong Xie, Zhi-Min Jin, Mao-Lin Hu, Liang-Pu Zhou
      Abstract: Three novel compounds, (η6-p-cymene)RuCl2(2-fluoro-5-aminopyridine) (compound 1), (η6-p-cymene)RuCl2(5-amino-2-chlorpyridine) (compound 2) and (η6-p-cymene)RuCl2(2-bromo- 5-aminopyridine) (compound 3), were synthesized and characterized. The compound 1 and 3 were determined by X-ray diffraction, showing a distorted piano-stool type of geometry with similar bond lengths and angles around the ruthenium. Compound 2 exhibited moderate in vitro activity against A549 and MCF-7 human cancer cells, the other two lower activities. The UV–vis and fluorescent absorption titrations showed that three compounds binded with CT-DNA in a minor groove. The intrinsic binding constants (Kb) were calculated to be 2.13(±0.03) × 105 M−1, 2.89(±0.03) × 105 M−1 and 2.45(±0.03) × 105 M−1 for compound 1, 2 and 3, respectively, by using UV–vis absorption titrations data. Among the three compound, the highest value of intrinsic binding constant of compound 2 was consistent with its highest cytoxicity against A549 and MCF-7 human cancer cells in vitro.Three novel compounds, (η6-p-cymene)RuCl2(2-X-5-aminopyridine) (X = F, Cl, Br), were synthesized and characterized. The X-ray diffraction revealed that the molecules containing substitutional F and Br atom showed a distorted piano-stool type of geometry. The UV-vis and fluorescent absorption titrations showed that three compounds binded with CT-DNA in a minor groove. The intrinsic binding constants (Kb) were 2.13(±0.03)×105 M−1, 2.89(±0.03) ×105 M−1 and 2.45(±0.03)×105 M−1 for compound containing substitutional F, Cl and Br atom, respectively. Among the three compounds, the highest value of intrinsic binding constant of compound containing substitutional Cl atom was consistent with its highest cytoxicity against A549 and MCF-7 human cancer cells in vitro.
      PubDate: 2017-07-20T03:32:37.218718-05:
      DOI: 10.1002/aoc.3923
       
  • An efficient synthesis and cytotoxic activity of
           2-(4-chlorophenyl)-1H–benzo[d]imidazole obtained using a magnetically
           recyclable Fe3O4 nanocatalyst-mediated white tea extract
    • Authors: Sara Shojaee; Mahnaz Mahdavi Shahri
      Abstract: A simple and efficient procedure has been developed for the synthesis of biologically relevant 2-substituted benzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes catalysed by iron oxide magnetic nanoparticles (Fe3O4 MNPs) in short reaction times with excellent yields. In the present study, Fe3O4 MNPs synthesized in a green manner using aqueous extract of white tea (Camelia sinensis) (Wt-Fe3O4 MNPs) were applied as a magnetically separable heterogeneous nanocatalyst to synthesize 2-(4-chlorophenyl)-1H–benzo[d]imidazole which has potential application in pharmacology and biological systems. Fourier transform infrared and NMR spectroscopies were used to characterize the 2-(4-chlorophenyl)-1H–benzo[d]imidazole. In vitro cytotoxicity studies on MOLT-4 cells showed a dose-dependent toxicity with non-toxic effect of 2-(4-chlorophenyl)-1H–benzo[d]imidazole, up to a concentration of 0.147 µM. The green synthesized Wt-Fe3O4 MNPs as recyclable nanocatalyst could be used for further research on the synthesis of therapeutic materials, particularly in nanomedicine, to assist in the treatment of cancer.In this research, the green synthesized Fe3O4 MNPs using aqueous extract of white tea has been applied as magnetically separable heterogeneous nanocatalyst to synthesize 2-(4-Chlorophenyl)-1 H benzo [d] imidazole which has potential application in pharmacology and biological systems. The present study successfully demonstrated a simple, eco-friendly method for the imidaozol with significant potential anticancer properties.
      PubDate: 2017-07-20T03:32:05.501733-05:
      DOI: 10.1002/aoc.3934
       
  • Synthesis of ferrocene-modified poly(glycidyl methacrylate) and its
           burning rate catalytic property
    • Authors: Weidong Zhou; Li Wang, Haojie Yu, Xia Xia
      Abstract: A series of ferrocene-modified poly(glycidyl methacrylate) (PGMA-Fc) compounds were synthesized and applied as burning rate catalysts in simulative solid propellant to overcome migration problems. 1H NMR and Fourier transform infrared spectroscopies and gel permeation chromatography were used to characterize the synthesized polymers. Their electrochemical behavior was evaluated using cyclic voltammetry. Their catalytic performance for the decomposition of ammonium perchlorate (AP) was investigated using thermogravimetric analysis. Anti-migration studies were conducted in migration tubes under 50°C. The results show that PGMA-Fc has a good catalytic effect on lowering the thermal decomposition temperature of AP. Anti-migration studies show that PGMA-Fc has better anti-migration performance than ferrocene and catocene.A series of ferrocene-modified poly(glycidyl methacrylate) (PGMA-Fc) compounds were synthesized and applied as burning rate catalysts in simulative solid propellant to overcome migration problems. Anti-migration studies show that PGMA-Fc has a good catalytic effect on lowering the thermal decomposition temperature of AP and better anti-migration performance than ferrocene and catocene.
      PubDate: 2017-07-20T03:25:55.907416-05:
      DOI: 10.1002/aoc.3932
       
  • Synthesis and characterization of SnO2/(NH4)2-SnCl6 nanocomposites loaded
           on activated carbon and its application for adsorption of methylene Blue
           and Orange G
    • Authors: Samane Jalali; Mahmood Reza Rahimi, Mehrorang Ghaedi, Arash Asfaram, Alireza Goudarzi
      Abstract: The present study deals with the synthesis and characterization (FE-SEM, particle size distribution, XRD and point of zero charge) SnO2/(NH4)2-SnCl6 nanocomposites loaded on activated carbon (SnO2/(NH4)2-SnCl6-NCs-AC) and its subsequent application for the simultaneous removal of Methylene Blue (MB) and Orange G (OG) from aqueous solution. Response surface methodology (RSM) based on central composite design (CCD) give trend of influencing responses with respect to five parameters such as contact time (X1), OG concentration (X2), MB concentration (X3), adsorbent mass (X4) and pH (X5). In later stage following recognition of significant variables and interaction, quadratic model generated which are able to predict the dyes removal in different conditions. Justification and selection of significant terms was conducted based on analysis of variance and Fisher's F-test Optimal value of contact time, OG concentration, MB concentration, adsorbent mass and pH were set at 4.0 min, 10 mg l−1, 20 mg L−1, 0.015 g and 6.0, respectively, which lead to achievement of best experiment removal percentage of 97.0 and 99.5% OG and MB respectively, from their binary solutions. The whole experimental data follow pseudo-first-order and pseudo-second-order rate equations. The fitting experimental data to more available conventional model like Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models revel more ability of Langmuir model (with R2 > 0.997) for explanation of system in equilibrium. The adsorption efficiency remained high even after the five cycle of reuse (99.76% and 95.56% for MB and OG, respectively).The present study deals with the synthesis and characterization SnO2/(NH4)2-SnCl6 nanocomposites loaded on activated carbon (SnO2/(NH4)2-SnCl6-NCs-AC) and its subsequent application for the simultaneous removal of Methylene Blue and Orange G from aqueous solution.
      PubDate: 2017-07-20T03:21:46.129491-05:
      DOI: 10.1002/aoc.3903
       
  • Preparation of chitosan functionalized end-capped Ag-NPs and composited
           with Fe3O4-NPs: Controlled release to pH-responsive delivery of
           progesterone and antibacterial activity against pseudomonas aeruginosa
           (PAO-1)
    • Authors: Faezeh Pourebrahim; Mehrorang Ghaedi, Kheibar Dashtian, Shadi Kheirandish, Ramin Jannesar, Vahid Pezeshkpour
      Abstract: In this work, functionalized chitosan end-capped Ag nanoparticles (NPs) and composited with Fe3O4-NPs was prepared as pH-responsive controlled release carrier for gastric-specific drug delivery. The structure of prepared material was characterized by FE-SEM, XRD, EDS and FT-IR analysis. The loading behavior of the progesterone onto this novel material was studied in aqueous medium at 25°C and their release was followed spectrophotometrically at 37°C in seven different buffer solutions (pH 1.2, 2.2, 3.2, 4.2, 5.2, 6.2 and 7.2) to simulate intestine and gastric media which experimental results reveal more release rate in pH 1.2 (gastric medium) with respect to other buffers. This observation is attributed to dependency of the CS-IMBDO-Ag-Fe3O4-NPs and progesterone structure with buffer pH that candidate this new material as prospective pH-sensitive carrier for gastric-targeted drug delivery. On the other hand, the antibacterial properties of this material against gram-negative bacterium pseudomonas aeruginosa (PAO-1) in agar plates was studied and accordingly based on broth micro dilution the minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) with respect to standard CLSI in different concentrations of CS-IMBDO-Ag-Fe3O4-NPs was calculated. The results reveal that MIC and MBC values are 50 and 1250 μg/mL, respectively. In addition, extracts of Portulaca oleracea leaves was prepared and its antibacterial activity in single and binary system with CS-IMBDO-Ag-Fe3O4-NPs as synergies effect against PAO-1 was tested and results shown that these materials have significant synergistic effect for each other.Functionalized chitosan end-capped Ag nanoparticles (NPs) composited with Fe3O4-NPs was prepared and characterized by FE-SEM, EDS and FT-IR analysis. The loading behavior of the progesterone onto this novel material was studied in aqueous medium at 25 °C and their release was followed spectrophotometrically some different solutions (buffered at pH 1.2, 2.2, 3.2, 4.2, 5.2,6.2 and 7.2) to simulate intestine and gastric media. The release rate in pH 1.2 (gastric medium) buffer is higher than that other buffers. Also, we investigated the antibacterial properties of this material against gram-negative bacterium pseudomonas aeruginosa (PAO-1) in agar plates.
      PubDate: 2017-07-16T23:37:15.312583-05:
      DOI: 10.1002/aoc.3921
       
  • Copper nanoparticles incorporated on a mesoporous carbon nitride, an
           excellent catalyst in the Huisgen 1,3-dipolar cycloaddition and
           N-arylation of N-heterocycles
    • Authors: Siyavash Kazemi Movahed; Parinaz Salari, Melika Kasmaei, Mahsa Armaghan, Minoo Dabiri, Mostafa M. Amini
      Abstract: Cu nanoparticles with average particles size around 10 nm were incorporated on the surface of a mesoporous carbon nitride support. The XRD and N2 adsorption isotherms show that it maintains a hexagonal mesoporous structure with a high surface area (600.03 m2 g−1). The embedded Cu nanoparticles exhibit extremely high catalytic performance in two different kinds of organic reactions. The Huisgen 1,3-dipolar cycloaddition and N-arylation of N-heterocycles were all accomplished.Copper nanoparticles around 10 nm were incorporated on the surface of a mesoporous carbon nitride support. The Huisgen 1,3-dipolar cycloaddition and N-arylation of N-heterocycles were all successfully accomplished.
      PubDate: 2017-07-16T23:01:19.198276-05:
      DOI: 10.1002/aoc.3914
       
  • Structural studies and biological activity evaluation of Pd(II), Pt(II)
           and Ru(II) complexes containing N-phenyl, N`-(3-triazolyl)thiourea
    • Authors: Ahmed M. Mansour
      Abstract: [MCl(H2L)(OH2)]·1.5H2O (M = Pd(II) (1) and Pt(II) (2)) and [Ru(H2L)2(OH2)2]·3H2O (3) (H3L: N-phenyl, N`-(3-triazolyl)thiourea) were synthesized, characterized and tested for their antibacterial activities against Staphylococcus aureus and Escherichia coli bacteria. The thiourea derivative is coordinated to Mn+ ions as a mono-negatively N,S-bidentate ligand via the enolization of C = S group and triazole N center. The density functional theory calculations reveal that presence of a water molecule in a trans position to triazole ring increased the stability of d8 metal ions complexes via the formation of strong Cl…NH intramolecular H-bond. The cis-Ru(II)-isomer with two isoenergetically H2L− molecules are more stable than the trans-analog. Coordination of H3L to Ru(II) ion did not alter the toxicity of the free ligand, while the interaction with the d8 metal ions gave rise to inactive compounds.DFT calculations reveal that presence of H2O, in the coordination spheres of Pd(II) and Pt(II) complexes of the title ligand, in a trans-position to the triazole ligand with increase the stability via the formation of strong Cl…NH hydrogen bond. Alternatively, the cis-isomer of Ru(II) complex is more stable than the trans-analog. The ligand interacts with the metal ions via the enolization of NH-C = S- group and triazole nitrogen atom as evidenced by the analytical and spectral tools.
      PubDate: 2017-07-11T02:35:49.738992-05:
      DOI: 10.1002/aoc.3928
       
  • Synthesis of innovative biochemical active mixed ligand metal(II)
           complexes with thiazole containing Schiff base: In vitro antimicrobial
           profile
    • Authors: Natarajan Raman; Thiravidamani Chandrasekar, Ganesan Kumaravel, Liviu Mitu
      Abstract: An unique Schiff base ligand, formed by the condensation reaction of 2-aminobenzothiazole with curcumin and its Cu(II), Ni(II), Co(II) and Zn(II) complexes incorporating 2,2′-bipyridine as coligand were synthesised. They were characterized via analytical and spectroscopic methods. The complexes adopt square planar geometry. Their antimicrobial activity and photocatalytic efficiency on Congo red dye molecule were explored. It is found that all the complexes are antimicrobial active and show higher activity than the ligand. The nuclease activity of the above metal complexes was also assessed by absorption titration, fluorescence, viscosity and gel electrophoresis assay. The complexes bind CT DNA through intercalation mode. The data reveal that the above synthesised metal(II) complexes are found to be effective metallonucleases. The gel electrophoresis results exhibit that the metal complexes cleave pBR322 plasmid DNA in presence of hydrogen peroxide effectively compared to the ligand. The synthesised metallonucleases should lead to a new era for the logical sketch of dominant agents for probing and targeting nucleic acids. This exploration reveals that Cu(II) complex has a valued biological and photochemical profile.A few novel mixed ligand metal(II) complexes were synthesized by the condensation of curcumin based Schiff base with 2-aminobenzothiazole and 2,2'-bipryidine and characterized by spectral and analytical data. They are identified as strong metallointercalators, potent DNA unfolding agents and have better biological profile. The complexes were also subjected to photocatalytic activity and inferred as potential catalysts for the degradation of Cango red dye. Among the metal complexes copper(II) complex has deserving biochemical profile.
      PubDate: 2017-07-07T05:00:51.929107-05:
      DOI: 10.1002/aoc.3922
       
  • Diethyldisulfoammonium chlorometallates as heterogeneous Brønsted–Lewis
           acidic catalysts for one-pot synthesis of
           14-aryl-7-(N-phenyl)-14H-dibenzo[a,j]acridines
    • Authors: Arup Kumar Dutta; Pinky Gogoi, Ruli Borah
      Abstract: A new series of Brønsted–Lewis acidic diethyldisulfoammonium chlorometallates, [DEDSA][FeCl4] and [DEDSA]2[Zn2Cl6], were synthesized as solid materials from the reaction of [(Et)2N(SO3H)2][Cl] ionic liquid with transition metal chlorides (FeCl3 and ZnCl2) at 80 °C in neat condition for 2 h. The chlorometallates were fully characterized using various spectroscopic and analytical techniques such as Fourier transform infrared, UV–visible and Raman spectroscopies, powder X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray and thermogravimetric analyses, Hammett acidity and elemental analyses. Their catalytic activity was studied as reusable heterogeneous catalysts for the three-component synthesis of novel 14-aryl-7-(N-phenyl)-14H-dibenzo[a,j]acridines under solvent-free conditions at 100 °C.Two Brønsted-Lewis acidic solid diethyl-disulfoammonium chlorometallates [DEDSA][FeCl4] and [DEDSA]2[Zn2Cl6] were synthesized from the reaction of [(Et)2N(SO3H)2][Cl] ionic liquid with transition metal chlorides (FeCl3 and ZnCl2) at 80 °C and evaluated as reusable heterogeneous catalyst for preparation of novel 14-aryl-7-(N-phenyl)-14H-dibenzo[a,j]acridines without solvent at 100 °C .The chlorometallates were confirmed by FT-IR, UV/Vis, Raman, PXRD, SEM-EDX, TGA, Hammett acidity and elemental analyses.
      PubDate: 2017-07-07T04:55:55.346066-05:
      DOI: 10.1002/aoc.3900
       
  • Antimicrobial and anticancer activities of Schiff base ligand and its
           transition metal mixed ligand complexes with heterocyclic base
    • Authors: H. F. Abd El-Halim; Gehad G. Mohamed, Mahmoud N. Anwar
      Abstract: A new Schiff base ligand (HL) was prepared via a condensation reaction of quinoline-2-carboxaldhyde with 2-aminophenol in a molar ratio of 1:1. Its transition metal mixed ligand complexes with 1,10-phenanthroline (1,10-phen) as co-ligand were also synthesized in a 1:1:1 ratio. HL and its mixed ligand complexes were characterized using elemental analysis, infrared, 1H NMR, mass and UV–visible spectroscopies, molar conductance, magnetic measurements, solid reflectance, thermal analysis, electron spin resonance and X-ray diffraction. Molar conductance measurements showed that all complexes have an electrolytic nature, except Cd(II) complex. From elemental and spectral data, the formulae [M(L)(1,10-phen)(H2O)]Clx⋅nH2O (where M = Cr(III) (x = n = 2), Mn(II) and Ni(II) (x = 1, n = 2), Fe(III) (x = n = 2), Co(II), Cu(II) and Zn(II) (x = 1, n = 2)) and [Cd(L)(1,10-phen)Cl]⋅3H2O for the metal complexes have been proposed. The geometric structures of complexes were found to be octahedral. Powder X-ray diffraction reflected the crystalline nature of the complexes; however, the Schiff base is amorphous. HL and its mixed ligand complexes were screened against Gram-positive bacteria (Streptococcus pneumoniae and Bacillus subtilis) and Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Antifungal activity was determined against Aspergillus fumigatus and Candida albicans, the data showing that most complexes had activity less than that of the Schiff base while Mn(II), Fe(III) and Ni(II) complexes showed no significant antifungal activity. The anticancer activity of HL and its metal complexes was also studied against breast and colon cell lines. The metal complexes showed IC50 higher than that of HL, especially the Cu(II) complex which showed the highest IC50 against breast cell line.The relation between M─O bond strength and inhibition zone diameter of metal complexes.
      PubDate: 2017-07-07T04:55:25.272053-05:
      DOI: 10.1002/aoc.3899
       
  • Biohybrid based on layered terbium hydroxide and applications as drug
           carrier and biological fluorescence probe
    • Authors: Ruijun Ju; Qingyang Gu
      Abstract: Aspirin (abbr. ASA) is intercalated into the layered terbium hydroxide (LTbH) by anion exchange method. Structure, chemical compositions, thermostability, morphology, luminescence property, cytotoxic effects and controlled-release behaviors have been investigated. The ASA molecules may embed between layers with monolayered vertical arrangement, and the thermal stability of organics was enhanced after intercalation. The Tb3+ luminescence in ASA-LTbH composites was enhanced compared with LTbH precusor and the luminescence intensity increased with the deprotonation degree. The cytotoxic effect of LTbH was observed with a sulforhodamine B (SRB) colorimetric assay, which revealed that the LTbH showed low cytotoxic effects. In addition, the ASA-LTbH composites exhibited a sustained release of ASA in Na2HPO4-NaH2PO4 buffer solution at pH 6.86 and 37°C. Construction of LRHs composites with drug molecules provided a beneficial pathway for preparing biohybrid based on LRHs, which may have potential applications in drug delivery carrier and biological fluorescence probe.Intercalation of aspirin (APC) into layered terbium hydroxide (LTbH) to form composites. The composites show excellent pharmaceutical properties and luminescence properties, which may have potential applications in drug carrier and biological fluorescence probe.
      PubDate: 2017-07-07T04:50:40.449535-05:
      DOI: 10.1002/aoc.3926
       
  • Synthesis of nanomagnetic supported thiourea–copper(I) catalyst and its
           application in the synthesis of triazoles and benzamides
    • Authors: Leila Mohammadi; Mohammad Ali Zolfigol, Ardeshir Khazaei, Meysam Yarie, Samira Ansari, Saeid Azizian, Maryam Khosravi
      Abstract: A novel nanomagnetic supported thiourea–copper(I) complex and inorganic–organic Takemoto-like hybrid nanomagnetic catalyst was designed, and synthesized. The prepared naomagnetic catalyst was characterized using Fourier transform infrared spectroscopy, X-ray diffraction, energy-dispersive X-ray analysis, transmission and scanning electron microscopies, thermogravimetry, nitrogen adsorption/desorption, zeta potential and vibrating sample magnetometry. Furthermore, the fabricated dual-role inorganic–organic hybrid catalyst shows a striking and robust catalytic activity for the synthesis of triazoles and benzamides through click and coupling reactions, respectively, under mild and eco-friendly reaction conditions.A novel inorganic–organic Takemoto-like hybrid nanomagnetic catalyst was constructed. The structural verification of the new catalyst was fully made by applying various methods. The fabricated dual-role hybrid catalyst showed striking and robust catalytic activity for the synthesis of triazoles and benzamides through click and coupling reactions, respectively, under mild and eco-friendly reaction conditions.
      PubDate: 2017-07-07T03:56:08.143194-05:
      DOI: 10.1002/aoc.3933
       
  • Simultaneous removal of Cu2+ and Cr3+ ions from aqueous solution based on
           Complexation with Eriochrome cyanine-R and derivative spectrophotometric
           method
    • Authors: Ahmad Reza Bagheri; Mehrorang Ghaedi, Kheibar Dashtian, Shaaker Hajati, Ali Akbar Bazrafshan
      Abstract: TiO2 nanoparticles deposited on activated carbon (TiO2–NP–AC) was prepared and characterized by XRD and SEM analysis. Subsequently, simultaneous ultrasound-assisted adsorption of Cu2+ and Cr3+ ions onto TiO2-NPs-AC after complexation via eriochrome cyanine R (ECR) has been investigated with UV–Vis and FAA spectrophotometer. Spectra overlapping of the ECR-Cu and ECR-Cr complex was resolve by derivative spectrophotometric technique. The effects of various parameters such as initial Cu2+ (A) and Cr3+ (B) ions concentrations, TiO2-NPs-AC mass (C), sonication time (D) and pH (E) on the removal percentage were investigated and optimized by central composite design (CCD). The optimize conditions were set as: 4.21 min, 0.019 mg, 20.02 and 13.22 mg L−1 and 6.63 for sonication time, TiO2–NP–AC mass, initial Cr3+ and Cu2+ ions concentration and pH, respectively. The experimental equilibrium data fitting to Langmuir, Freundlich, Temkin and Dubinin–Radushkevich models show that the Langmuir model is a good and suitable model for evaluation and the actual behavior of adsorption process and maximum adsorption capacity of 105.26 and 93.46 mg g−1 were obtained for Cu2+ and Cr3+ ions, respectively. Kinetic evaluation of experimental data showed that the adsorption processes followed well pseudo second order and intraparticle diffusion models.TiO2 nanoparticles deposited on activated carbon (TiO2–NP–AC) was prepared and characterized by XRD and SEM analysis. Subsequently, simultaneous ultrasound-assisted adsorption of Cu2+ and Cr3+ ions onto TiO2-NPs-AC after complexation via eriochrome cyanine R (ECR) has been investigated with UV–Vis and FAA spectrophotometer. Spectra overlapping of the ECR-Cu and ECR-Cr complex was resolve by derivative spectrophotometric technique.
      PubDate: 2017-07-07T03:46:03.304041-05:
      DOI: 10.1002/aoc.3918
       
  • Synthesis of soluble and meltable pre-ceramic polymers for Zr-containing
           ceramic nanocomposites
    • Authors: Xin Long; Changwei Shao, Jun Wang, Yanzi Gou
      Abstract: Polymer-derived methods are one of the most important tools for the synthesis of ceramics with a finely dispersed microstructure. In this study, a soluble and meltable ZrC/C pre-ceramic polymer, P-DACZ, (which would later exhibit a high ceramic yield of 71 wt%) was synthesized via radical polymerization. By adding low molecular weight polycarbosilane in any proportion during the radical polymerization process of P-DACZ, a soluble and meltable ZrC/SiC/C pre-ceramic precursor, PCS-DACZ (which would later exhibit a high ceramic yield of>80 wt%) was synthesized. After annealing at 1400 °C under an argon flow, the precursors converted into bulk ZrC/C and ZrC/SiC/C ceramic nanocomposites. The ZrC nanoparticles could resist any grain growth when heat-treated at temperatures above 1800 °C because the C or SiC matrix prevented long-range atomic diffusion of zirconium. Such ceramic nanocomposites would be suitable for structural and (multi)functional applications at harsh environments with high temperatures.The synthesized soluble and meltable pre-ceramic polymers can convert into bulk ZrC/C and ZrC/SiC/C ceramic nanocomposites after annealing at 1400 °C under an argon flow. The ZrC nanoparticles could resist any grain growth when heat treated at temperatures above 1800 °C because the C or SiC matrix prevented long range atomic diffusion of zirconium.
      PubDate: 2017-07-05T03:11:15.699372-05:
      DOI: 10.1002/aoc.3942
       
  • N-(3-silyl propyl) diethylene triamine N,N',N''-tri-sulfonic acid
           immobilized on Fe3-xTixO4 magnetic nanoparticles: A new recyclable
           heterogeneous nanocatalyst for the synthesis of hexahydroquinolines
    • Authors: Davood Azarifar; Younes Abbasi, Omolbanin Badalkhani
      Abstract: In the present study, for the first time N-(3-silyl propyl) diethylene triamine N,N',N''-tri-sulfonic acid (SPDETATSA) was grafted on magnetic Fe3-xTixO4 nanoparticles. The structure of the resulted nanoparticles was characterized based on Fourier-transform infrared (FT-IR), energy-dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermal gravimetric analysis (TGA), and vibrating sample magnetometer (VSM) analyses. The results confirmed the successful immobilization of sulfamic acid groups onto the magnetic support. These nanoparticles exhibited high catalytic activity as novel magnetically recyclable acid nanocatalyst in the synthesis of a diverse range of hexahydroquinolines through one-pot tandem reactions in excellent yields. Also, this nanocatalyst performed satisfactory catalytic maintenance of activity for the synthesis of the reaction products after 4 rounds of recycling with no considerable loss of activity.For the first time N-(3-silyl propyl) diethylene triamine N,N',N''-tri-sulfonic acid (SPDETATSA) was grafted on magnetic Fe3-xTixO4 nanoparticles. The structure of the resulted nanoparticles was characterized based on FT-IR, EDX, SEM, TEM, TGA and VSM techniques. These nanoparticles exhibited high catalytic activity in synthesis of hexahydroquinolines from tandem reactions in excellent yields.
      PubDate: 2017-07-05T03:05:56.639567-05:
      DOI: 10.1002/aoc.3939
       
  • Supported copper (I) catalyst from fish bone waste: An efficient, green
           and reusable catalyst for the click reaction toward N-substituted
           1,2,3-TRIAZOLES
    • Authors: Xingquan Xiong; Zhongke Tang, Zhaohong Sun, Xiaoqing Meng, Sida Song, Zhilong Quan
      Abstract: An eco-efficient, green, and multi-gram procedure is presented for one-pot multicomponent synthesis of N-substituted 1,2,3-triazoles by using waste fishbone powders supported CuBr (FBPs-CuBr) as catalyst. FBPs-CuBr is found to be an efficient heterogeneous catalyst and a series of 1,2,3-triazoles are obtained in moderate to excellent yields in water under MW irradiation (70–98%). It can be separated conveniently by a simple filtration and reused at least seven consecutive runs with a slight drop in the product yields. Furthermore, the desired product still could be obtained in 80% yield when the scale of the reaction was increased to 40.0 mmol.Waste fishbone powders supported CuBr (FBPs-CuBr) was developed for the synthesis of N-substituted 1, 2, 3-triazoles in good to excellent yields under microwave-assisted condition. The N-substituted 1, 2, 3-triazole in the model reaction could be prepared in 80% yield even when the reaction scale was increased to 40 mmol.
      PubDate: 2017-07-05T03:01:11.118749-05:
      DOI: 10.1002/aoc.3946
       
  • Click approach to the three-component synthesis of novel
           β-hydroxy-1,2,3-triazoles catalysed by new (Cu/Cu2O) nanostructure as a
           ligand-free, green and regioselective nanocatalyst in water
    • Authors: Hadi Esmaeili-Shahri; Hossein Eshghi, Jalil Lari, Seyyed Amin Rounaghi
      Abstract: Copper nanostructures were produced as an effective and regioselective catalyst for the synthesis of 1,2,3-triazoles from a wide range of raw materials, such as sodium azide, epoxides and terminal alkynes, in water via a one-pot three-component click reaction. The new heterogeneous catalyst was prepared by a simple ball mill reduction of CuO with NaBH4 using a ball-to-powder weight ratio of 50:1 under air atmosphere at room temperature. The catalyst was fully characterized using scanning electron microscopy, energy-dispersive X-ray analysis, Fourier transform infrared spectroscopy and X-ray diffraction. The copper nanostructures catalysed both ring opening and triazole cyclization steps. Products were obtained in high yields and short reaction times. The reactions were performed at ambient temperature in water as a green solvent. The Cu/Cu2O nanostructures revealed high reusability and high stability via a simple recycling process.1,4-Disubstituted 1,2,3-triazoles were synthesized from sodium azide, epoxides and terminal alkynes in water via a one-pot three-component click reaction. Cu/Cu2O nanostructures as a regioselective and reusable catalyst were used in the synthesis. This method has many advantages including the use of water as a green solvent under mild conditions.
      PubDate: 2017-07-05T03:00:38.53054-05:0
      DOI: 10.1002/aoc.3947
       
  • Magnetic Fe3O4 nanoparticles supported imine/Thiophene-nickel (II)
           complex: A new and highly active heterogeneous catalyst for the synthesis
           of polyhydroquinolines and 2, 3-dihydroquinazoline-4(1H)-ones
    • Authors: Lotfi Shiri; Leili Heidari, Mosstafa Kazemi
      Abstract: A new magnetically separable nickel catalyst (Ni(NO3)2−Imine/Thiophene-Fe3O4@SiO2) was readily prepared and structurally characterized by Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDX), Vibrating sample magnetometer (VSM), X-Ray diffraction (XRD) and Atomic absorption spectroscopy (AAS). The Ni(NO3)2−Imine/Thiophene-Fe3O4@SiO2 exhibited efficient catalytic activity in the synthesis of 2,3-dihydroquinazoline-4(1H)-ones and polyhydroquinolines. Catalysis research under water and solvent-free conditions makes also this synthetic protocol ideal and fascinating from the environmental point of view. The catalyst can be magnetically recovered after the reaction and can be reused for many times without appreciable decrease in activity.Magnetic Fe3O4 nanoparticles supported Imine/Thiophene-nickel (II) complex (Ni(NO3)2−Imine/Thiophene-Fe3O4@SiO2) was shown to be a versatile and highly efficient reusable catalyst for the synthesis of polyhydroquinoline and 2,3-dihydroquinazoline-4(1H)-one derivatives.
      PubDate: 2017-07-05T02:55:52.748348-05:
      DOI: 10.1002/aoc.3943
       
  • Polymerization of graphene oxide nanosheet by using of aminoclay:
           Electrocatalytic activity of its platinum nanohybrids
    • Authors: S. Jafar Hoseini; Mehrangiz Bahrami, Mahnaz Maddahfar, Roghayeh Hashemi Fath, Mahmoud Roushani
      Abstract: This study describes the polymerization of graphene oxide (GO) nanosheet to reduced-GO-aminoclay (RGC) by covalent functionalization of chemically reactive epoxy groups on the basal planes of GO with amine groups of magnesium phyllosilicate clay (known as aminoclay). The resulting RGC sheets were characterized and applied to support platinum nanostructures at toluene/water interface. Pt nanoparticles (NPs) with diameters about several nanometers were adhered to RGC sheets by chemical reduction of [PtCl2(cod)] (cod = cis,cis-1,5-cyclooctadiene) complex. Catalytic activity of Pt NPs thin films were investigated in the methanol oxidation reaction. Cyclic voltammetry results exhibit that the Pt/reduced-GO (RGO) and Pt/RGC thin films showed improved catalytic activity in methanol oxidation reaction in comparison to other Pt NPs thin films, demonstrating that the prepared Pt/RGO and Pt/RGC thin films are promising catalysts for direct methanol fuel cell.In this study, we have compared the electrocatalytic activity of Pt/reduced graphene oxide and Pt/reduced graphene-clay thin films in methanol oxidation reaction that showed improved catalytic activity in comparison to other Pt nanoparticle thin films.
      PubDate: 2017-07-05T02:51:15.231724-05:
      DOI: 10.1002/aoc.3894
       
  • Synthesis and characterization of sulfamic acid supported on Fe3O4
           nanoparticles: A green, versatile and magnetically separable acidic
           catalyst for oxidation reactions and Knoevenagel condensation
    • Authors: Lotfi Shiri; Hojatollah Narimani, Mosstafa Kazemi
      Abstract: Sulfamic acid immobilized on diethylenetriamine functionalized Fe3O4 nanoparticles (SA-DETA-Fe3O4) was successfully prepared and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), vibrating sample magnetometer (VSM), thermo gravimetric analysis (TGA), X-Ray diffraction (XRD) and scanning electron microscopy (SEM). The sulfamic acid was found as a magnetically separable and highly active catalyst for the oxidative coupling thiols, oxidation of sulfides. Furthermore, the SA-DETA-Fe3O4 showed the high catalytic activity in Knoevenagel condensation of aromatic aldehydes with active methylene compounds (malononitrile and ethyl cynoacetate). The nanosolid catalyst could be easily recovered by a simple magnetic separation and reused for many cycles without deterioration in catalytic activity.Sulfamic acid immobilized on amino-functionalized magnetic Fe3O4 nanoperticles (SA-DETA-Fe3O4) was shown to be a versatile and highly efficient reusable catalyst for theorganic oxidation reactions and Knoevenagel condensation.
      PubDate: 2017-07-05T02:41:07.122614-05:
      DOI: 10.1002/aoc.3927
       
  • Structural designing, spectral and computational studies of bioactive
           Schiff's base ligand and its transition metal complexes
    • Authors: Seema Gautam; Sulekh Chandra, Hament Rajor, Swati Agrawal, Praveen Kumar Tomar
      Abstract: Transition metal complexes of Mn(II) and Ni(II) have been synthesized with novel bioactive Schiff's base ligand. Schiff's base ligand i.e. benzoylacetone-bis(2-amino-4-methylbenzothioazole) has been synthesized via condensation reaction between 2-amino-4-methylbenzothioazole and benzoylacetone in 2:1 ratio, respectively. Synthesized ligand has been characterized using elemental analysis, infra-red, 1H–NMR and mass spectroscopy techniques. Characterization of complexes was based on magnetic moment, molar conductance, elemental analysis, electronic spectra, infra-red and EPR spectroscopic techniques. Molar conductance data suggest that metal complexes are non-electrolytic in nature. Therefore, these complexes are formulated as [M(L)X2], where M = Mn(II), Ni(II), L = Schiff's base ligand, X = Cl−, CH3COO−, NO3−. Data of characterization study suggest octahedral geometry for Mn(II) and Ni(II) complexes. Geometry of metal complexes was also optimized with the help of computational study i.e. molecular modelling. Computational study also suggests octahedral geometry for complexes. Free ligand as well as its all metal complexes have been screened against the growth of pathogenic bacteria (E.coli, S.aureus) and fungi (C.albicans, C.krusei, C.parapsilosis, C.tropicalis) to assess their inhibition potential. The inhibition data revealed that metal complexes exhibit higher inhibition potential against the growth of bacteria and fungi microorganisms than free ligand.Synthesis and characterization of novel bioactive Schiff's base ligand and its metal complexes were done by various spectral techniques, molecular modelling.On the basis of characterization study data, metal complexes possess six coordinated octahedral geometry.Thermal data suggested that metal complexes are more thermal stable than free Schiff's base ligand.In vitro antibacterial and antifungal activity of synthesized ligand and its metal complexes were screened.All metal complexes were more biologically sensitive than ligand against the growth of microorganism.
      PubDate: 2017-07-05T02:35:37.330218-05:
      DOI: 10.1002/aoc.3915
       
  • Synthesis, structure and in vitro antiproliferative activities of
           oxamido-bridged dicopper(II) complexes: A comparative study of
           experimental evidence and molecular docking of DNA/protein binding
    • Authors: Ling-Yang Wang; Kang Zheng, Yan-Tuan Li, Zhi-Yong Wu, Cui-Wei Yan
      Abstract: Two μ-oxamido-bridged dicopper(II) complexes, namely [Cu2(hmpoxd)(H2O)(phen)](ClO4) (1) and [Cu2(papo)(H2O)(phen)](ClO4)·2H2O (2), where H3hmpoxd and H3papo represent N-(2-hydroxy-5-methylphenyl)-N′-[3-(dimethylamino)propyl]oxamide and N-(2-hydroxylphenyl)-N′-(3-aminopropyl)oxamide, respectively, and phen represents 1,10-phenanthroline, were synthesized. Single-crystal X-ray crystallography and other methods revealed that the two copper(II) ions in complex 1 are bridged by the cis-hmpoxd3− with Cu···Cu separation of 5.1896(7) Å, in which the inner (Cu1) and outer (Cu2) copper(II) atoms are located in square-planar and square-pyramidal geometries, respectively. To evaluate the effects of bridging ligand hydrophobicity on DNA/protein binding and potential anticancer activities, comparative studies of the reactivity towards herring sperm DNA and protein bovine serum albumin (BSA) as well as cytotoxicity of complex 1 with our previously reported complex 2 were conducted theoretically and experimentally. The results indicate that the two complexes can interact interactively with DNA, and bind to BSA via the binding sites Trp213 for 1 and Trp134 for 2. Interestingly, the in vitro anticancer activities and DNA/protein binding affinities consistently follow the order of 1> 2.The DNA/BSA binding properties of synthesized dicopper(II) complexes are studied theoretically and experimentally. The importance of bridging ligand hydrophobicity is highlighted.
      PubDate: 2017-07-05T02:25:54.914113-05:
      DOI: 10.1002/aoc.3940
       
  • Equisetum arvense As an abundant source of silica nanoparticles.
           SiO2/H3PW12O40 nanohybrid material as an efficient and environmental
           benign catalyst in the synthesis of 2-amino-4H-chromenes under
           solvent-free conditions
    • Authors: Reza Tayebee; Akbar Pejhan, Hassan Ramshini, Behrooz Maleki, Nasrin Erfaninia, Zohre Tabatabaie, Effat Esmaeili
      Abstract: Uniform SiO2 nanoparticles were successfully prepared from Equisetum arvense obtained from the north-east of Iran. Then, surface modification of the extracted nanoparticles was performed with a methanol solution of H3PW12O40 via wet impregnation method. The prepared nanocatalyst was characterized by XRD, FESEM, ICP, UV–Vis, and FT-IR spectroscopy. The supported heterogeneous nanocatalyst was successfully applied as a Lewis/Bronsted acid catalyst in the synthesis of a series of substituted 4H–chromenes via condensation of aromatic aldehydes, malononitrile, and 4-hydroxycoumarin under solventless conditions with fine yields in appropriately short times.SiO2/HPA nanoparticles were prepared, characterized and performed as efficient heterogeneous acid catalyst in the synthesis of substituted 4H–chromenes under solventless conditions.
      PubDate: 2017-07-05T02:20:51.035239-05:
      DOI: 10.1002/aoc.3924
       
  • Assembly immobilized palladium(0) on carboxymethylcellulose/Fe3O4 hybrid:
           An efficient tailor-made magnetically catalyst for the Suzuki–Miyaura
           couplings
    • Authors: Zhuan Zhang; Yizong Zhang, Xiaoping Liu, Binbin Shen, Tianzhu Zhang, Yiqun Li
      Abstract: The Pd nanoparticles (Pd NPs) embedded on magnetically retrievable carboxymethylcellulose/Fe3O4 (Pd0@CMC/Fe3O4) organic/inorganic hybrid were prepared via the conventional simple process. The presence of the hydroxyl and carboxyl groups within the framework of the magnetic hybrid enables the facile preparation and stabilization of Pd NPs in this organic/inorganic hybrid. This hybrid catalyst was very effective in the Suzuki–Miyaura reaction of a variety of aryl halides with arylboronic acid to afford excellent product yields. The catalyst showed good stability and could be easily recovered with an external magnetic field and reused for several times without a significant loss in its catalytic activity. Furthermore, the Pd0@CMC/Fe3O4 hybrid catalyst was fully characterized by UV–Vis, FT–IR, XRD, SEM, EDX, TEM, XPS and TGA techniques. The hot filtration test suggests that a homogeneous mechanism is operative in Suzuki–Miyaura reaction.A novel magnetic organic/inorganic hybrid materials (CMC/Fe3O4) supported Pd nanoparticles (Pd0@CMC/Fe3O4) was prepared by a simple and low-cost approach without using any expensive organosilane. The as-synthesized Pd0@CMC/Fe3O4 hybrid exhibited excellent catalytic activities for Suzuki–Miyaura cross-coupling reactions in excellent yields.
      PubDate: 2017-07-05T02:16:10.720023-05:
      DOI: 10.1002/aoc.3912
       
  • Fe3O4-Methylene diphenyl diisocyanate-guanidine (Fe3O4–4,4′-MDI-Gn): A
           novel superparamagnetic powerful basic and recyclable nanocatalyst as an
           efficient heterogeneous catalyst for the Knoevenagel condensation and
           tandem Knoevenagel-Michael-cyclocondensation reactions
    • Authors: Razieh Maleki; Nadiya Koukabi, Eskandar Kolvari
      Abstract: In this paper, guanidine groups (Gn) supported on modified magnetic nanoparticles (Fe3O4–4,4′-MDI) were synthesized for the first time. The catalyst synthesized was characterized by various techniques such as SEM (Scanning Electron Microscopy), TEM (Transmission electron microscopy), XRD (X-ray Diffraction), TGA (Thermogravimetric ananlysis), EDS (Energy-dispersive X-ray spectroscopy) and VSM (vibrating sample magnetometer). The catalyst activity of modified MNPs–MDI-Gn, as powerful basic nanocatalyst, was probed through the Knoevenagel and Tandem Knoevenagel–Michael-cyclocondensation reactions. Conversion was high under optimal conditions, and reaction time was remarkably shortened. This nanocatalyst could simply be separated and recovered from the reaction mixture by simple magnetic decantation and reused many times without significant loss of its catalytic activity. Also, the nanocatalyst could be recycled for at least seven (Knoevenagel condensation) and six (Knoevenagel and Tandem Knoevenagel–Michael-cyclocondensation) additional cycles after they were separated by magnetic decantation and, washed with ethanol, air-dried, and immediately reused.In this paper, we successfully synthesized supported iron oxide magnetic nanoparticles (Fe3O4–4,4′-MDI-Gn) from readily available starting materials. It was applied as magnetically recyclable and powerful basic heterogeneous nanocatalyst for the Knoevenagel and Tandem Knoevenagel–Michael-cyclocondensation reactions in excellent yields and short reaction times. This nanocatalyst could simply be separated and recovered from the reaction mixture by simple magnetic decantation and reused many times without significant loss of its catalytic activity. Furthermore, the catalyst could be recovered and reused without significant degradation in activity.
      PubDate: 2017-07-05T02:10:40.748112-05:
      DOI: 10.1002/aoc.3905
       
  • Electronic structures and photophysical properties of phosphorescent
           platinum (II) complexes with tridentate C^N*N cyclometalated ligands
    • Authors: Wenqian Li; Jian Wang, Xi Yan, Huize Zhang, Wei Shen
      Abstract: To get an insight into the structure–property relationships in a series of strongly phosphorescent platinum(II) complexes with tridentate C^N*N cyclometalated ligands, their electronic structures and electroluminescence properties were systematically investigated via density functional theory and time-dependent density functional theory. Moreover, the factors related to the radiative and non-radiative decay process, including the transition electric dipole moment μ(Sn), the energy difference between singlet and lowest triplet excited states ΔE(Sn–T1) and the spin–orbital coupling matrix elements ⟨Sn ĤSOC T1⟩, as well as the energy gap between T1 and S0 states ΔE(T1–S0) and absorption–emission Stokes shifts have been calculated. Fine emission color tuning and high phosphorescence quantum yield of phosphorescent complexes may be achieved through introducing five–six-membered metallacycle geometries and linking a substituent (such as phenyl) at bridge atoms. Additionally, phosphorescent properties of these complexes show a clear dependence on the electronegativity of bridge atoms.Heteroatoms were incorporated into the bridges between two pyridyls in main ligands to study the structure–property relationships of cyclometalated Pt(II) complexes and inspire new ideas for designing tridentate Pt(II) complexes.
      PubDate: 2017-06-29T02:35:46.603326-05:
      DOI: 10.1002/aoc.3929
       
  • Novel CuFe2O4@SiO2-OP2O5H magnetic nanoparticles: Preparation,
           characterization and first catalytic application to the synthesis of
           1,8-dioxo-octahydroxanthenes
    • Authors: Farzaneh Tajfirooz; Abolghasem Davoodnia, Mehdi Pordel, Mahmoud Ebrahimi, Amir Khojastehnezhad
      Abstract: New functionalized magnetic core–shell nanoparticles, CuFe2O4@SiO2-OP2O5H, were prepared by grafting of phosphorus pentoxide on CuFe2O4@SiO2 nanoparticles and characterized using Fourier transform infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray analysis, inductively coupled plasma optical emission spectrometry and vibrating sample magnetometry. The catalytic activity of CuFe2O4@SiO2-OP2O5H as a novel catalyst was evaluated in the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions. The results showed that the catalyst has high activity and the desired products are obtained in high yields within short reaction times. The catalyst is readily recovered using magnetic decantation and can be used at least four times without noticeable deterioration in catalytic activity.New functionalized magnetic core–shell nanoparticles, CuFe2O4@SiO2-OP2O5H, were prepared by grafting of phosphorus pentoxide on CuFe2O4@SiO2 nanoparticles and characterized. The catalytic activity of CuFe2O4@SiO2-OP2O5H was evaluated in the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions. The catalyst has high activity leading to products in high yields within short reaction times. The catalyst is readily recovered by magnetic decantation and can be used at least four times without loss of catalytic activity.
      PubDate: 2017-06-29T02:30:54.554761-05:
      DOI: 10.1002/aoc.3930
       
  • Preparation, characterization and biological evaluation of two chiral
           binuclear copper(II) complexes
    • Authors: Jing-Jing Suo; Zhong-Ying Ma, Jing-Yuan Xu, Jin-Lei Tian, Xin Liu
      Abstract: Two chiral Cu(II) complexes of [Cu2(R-L)2](PF6)2·2C2H5OH (1) and [Cu2(S-L)2](PF6)2·2C2H5OH (2) (HL = 2-(Bis(quinolin-2-ylmethyl)amino)-1-propanol) were designed and synthesized to serve as chemical nucleases and anticancer drugs. X-ray crystallography revealed that two complexes contain chiral binuclear cations and PF6− anions. The interaction of two complexes with CT-DNA was researched via various spectroscopic techniques and viscosity measurement, indicating that the complexes were bound to CT-DNA by a classical intercalation binding mode. In addition, the two complexes exhibited remarkable DNA cleavage activity with an optimal dosage of 10 μM in the absence of any exogenous oxidant agent. Both of the complexes showed excellent in vitro cytotoxicity on A549 cell lines with IC50 values in the low micromolar range. Moreover, complex 2 could damage DNA of A549 cells into fragmentation and then induced cell apoptosis in a dose-dependent manner, which was demonstrated by comet assay and Hoechst 33342 staining experiment. Further research showed that complex 2 could also induce G2 and S phase cell cycle arrest.In this contribution, we designed and synthesized two chiral binuclear Cu(II) complexes 1 and 2. Both of them exhibited remarkable DNA binding and cleavage ability. Moreover, they showed excellent in vitro cytotoxicity on A549 cell lines, and induced cell apoptosis and G2 and S phase cell cycle arrest, indicating 1 and 2 can be anticancer drug candidates.
      PubDate: 2017-06-29T02:16:27.411349-05:
      DOI: 10.1002/aoc.3911
       
  • Synthesis and characterization of the novel diamine-functionalized
           Fe3O4@SiO2 nanocatalyst and its application for one-pot three-component
           synthesis of chromenes
    • Authors: Ali Maleki; Reza Ghalavand, Razieh Firouzi Haji
      Abstract: Fe3O4@SiO2@propyltriethoxysilane@o-phenylendiamine as an environmentally-benign functionalized silica-coated magnetic organometallic nanomaterial has been synthesized and characterized by Fourier transforms infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM) images and energy dispersive X-ray (EDX) and vibrating sample magnetometer (VSM) analyses. Then, its catalytic activity was investigated for the one-pot three-component condensation reaction between dimedone, malononitrile and various substituted aromatic aldehydes to afford the corresponding 2-amino-4H-chromene derivatives under mild reaction conditions. This nanocatalyst can be easily recovered from the reaction mixture by using a magnet and reused for at least five times without significant decrease in catalytic activity.A new and environmentally-benign OPDA-functionalized silica-coated magnetic heterogeneous catalyst have been synthesized and its activity was investigated for the one-pot three-component condensation reaction between aromatic aldehydes, dimedone and malononitrile to afford the corresponding chromene derivatives under mild reaction conditions.
      PubDate: 2017-06-29T02:15:52.655689-05:
      DOI: 10.1002/aoc.3916
       
  • Simultaneous formation of platinum-based nanocatalysts and degradation of
           dyes at oil/water interface: Comparative morphological and kinetic studies
           
    • Authors: Mehrangiz Bahrami; S. Jafar Hoseini
      Abstract: To decrease the water pollution of textile industries with a large amount of toxic and non-biodegradable colored dye effluents, an efficient technique is required to safely remove harmful pollutants. In this paper, the reaction between azo dyes and NaBH4 catalyzed by nanoparticles (NPs) thin films has been studied. We report insitu degradation of methyl orange (MO) and methyl red (MR) by using Pt-based thin films monitored by UV–Vis spectroscopy. We have synthesized different thin films such as Pt, PtPd, PtFeFe2O3, PtNi and PtAu films from Pt organometallic precursor in the MO and MR medium (dye degradation and NPs formation is happened simultaneously) and activity of these films were compared in the complete degradation of MO and MR dyes. Rate constants for the catalyzed reactions have been determined. PtPd NPs thin film has shown the highest rate constant for the degradation of MO and MR within only a few seconds due to its well-ordered structure. Furthermore, the effect of presence of MO on the morphology of NPs was investigated.Insitu degradation of methyl orange (MO) and methyl red (MR) is investigated by using Pt-based thin films that monitored by UV–Vis spectroscopy. Different thin films was synthesized such as Pt, PtPd, PtFeFe2O3, PtNi and PtAu films by using organometallic Pt precursor in the MO and MR medium (dye degradation and NPs formation is happened simultaneously) and activity of these films were compared in the complete degradation of MO and MR dyes.
      PubDate: 2017-06-29T02:11:19.687025-05:
      DOI: 10.1002/aoc.3920
       
  • A mixed-ligand quinazoline-based Ni(II) Schiff base complex: Synthesis,
           characterization, crystal structure, antimicrobial investigation and
           catalytic activity for the synthesis of
           2H–indazolo[2,1-b]phthalazine-triones
    • Authors: Fateme Khajoee Nejad; Mehrji Khosravan, S. Yousef Ebrahimipour, Franco Bisceglie
      Abstract: A tridentate Schiff base ligand, (E)-3-((2-hydroxy-3-methoxybenzylidene)amino)-2-methylquinazolin-4(3H)-one [HL], and its mixed-ligand Ni(II) complex [Ni(L)(imi)], were synthesized and fully characterized using elemental analysis, FT-IR, UV–Vis and 1HNMR spectroscopy techniques. The structure of the synthesized ligand and complex was determined with single crystal X-ray diffraction method. In the complex, a square planner geometry was observed around the Ni(II) central atom coordinated with the donor atoms of the Schiff base ligand and one nitrogen of imidazole group. In addition, the catalytic activity of the complex on the three-component condensation of hydrazine hydrate with phthalic anhydride and dimedone to obtain 2H–indazolo[2,1-b]phthalazine-triones was investigated. Furthermore, in-vitro antimicrobial studies were performed that indicated the great antibacterial activities of the Ni(II) complex against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus bacteria.A novel mixed-ligand quinazoline-based Ni(II) Schiff base complex was used as an efficient catalyst for the synthesis of 2H–indazolo[2,1-b]phthalazine-triones. The synthesized Ni(II) complex also showed better antibacterial activity compared with the parent Schiff base ligand.
      PubDate: 2017-06-29T02:10:27.631026-05:
      DOI: 10.1002/aoc.3907
       
  • Ni@Pd nanoparticles supported on ionic liquid-functionalized KCC-1 as
           robust and recyclable nanocatalysts for cycloaddition of propargylic
           amines and CO2
    • Authors: Seyed Mohsen Sadeghzadeh; Rahele Zhiani, Shokufe Emrani
      Abstract: Novel heterogeneous catalyst systems comprised of a fibrous nanosilica-supported nano-Ni@Pd-based ionic liquid (KCC-1/IL/Ni@Pd) are described for the cyclization of propargylic amines with CO2 to provide 2-oxazolidinones. KCC-1 with high surface area was functionalized with IL acting as a robust anchor so that the nano-Ni@Pd was well dispersed on the fibres of the KCC-1 microspheres, without aggregation. Because of the amplification effect of IL, high loading capacities of the nanocatalysts were achieved. The reported synthesis includes several advantages like solvent-free conditions, operational simplicity, short reaction times, environmentally benign reaction conditions, cost effectiveness, high atom economy and excellent yields, making it a genuinely green protocol.Novel heterogeneous catalyst systems comprised of a fibrous nanosilica-supported nano-Ni@Pd-based ionic liquid (KCC-1/IL/Ni@Pd) are described for the cyclization of propargylic amines with CO2 to provide 2-oxazolidinones.
      PubDate: 2017-06-29T02:06:30.966309-05:
      DOI: 10.1002/aoc.3941
       
  • A novel Prussian blue-magnetite composite synthesized by self-template
           method and its application in reduction of hydrogen peroxide
    • Authors: Wei Cai; Songhai Wu, Yong Liu, Danlin Li
      Abstract: A novel Prussian blue (PB)-Fe3O4 composite has been prepared for the first time by self-template method using PB as the precursor. According to this method, Fe3O4 nanoparticles distributed uniformly on the surface of PB cube. The feed ratio of sodium acetate to PB has been proved to be a key factor for magnetic properties and electro-catalysis properties of the composite. Under the experimental conditions, the saturation magnetization value (Ms) of PB-Fe3O4–2 composite was 22 emug−1, while the Ms value of other samples reduced. The composites also showed a good peroxidase-like activity for the oxidation of substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2. The catalytic reduction of hydrogen peroxide capacity was PB-Fe3O4–1> PB-Fe3O4–2> PB-Fe3O4–3> PB-Fe3O4–0, which confirmed the Fe(II) centres in PB surface and Fe3O4 nanoparticles had synergistic effect on catalytic reduction of hydrogen peroxide.Herein, a self-template method that PB was used not only as the template but also as iron source for the formation of Fe3O4 nanoparticles was used to synthesize a novel composite material, which consists of micron-sized PB cube and nano-scale Fe3O4 spherical particles. Moreover, magnetic and electrochemical properties were investigated. Besides, the composites were applied in a promising catalyst for the reduction of hydrogen peroxide.
      PubDate: 2017-06-29T02:01:19.995285-05:
      DOI: 10.1002/aoc.3909
       
  • Ferrocene based chiral binuclear η6-benzene-Ru(II)-phosphinite complexes:
           Synthesis, characterization and catalytic activity in asymmetric reduction
           of ketones
    • Authors: Yaser W. Abdlhmed Al-bayati; Duygu Elma Karakaş, Nermin Meriç, Murat Aydemir, Feyyaz Durap, Akın Baysal
      Abstract: In the present study, a series of chiral C2-symmetric ferrocenyl based binuclear η6-benzene-Ru(II) complexes bearing diphenylphosphinite and diisopropylphosphinite moieties have been synthesised. The new binuclear η6-benzene-Ru(II)-phosphinite complexes were characterised based on nuclear magnetic resonance (1H, 13C, 31P–NMR), FT-IR spectroscopy and elemental analysis. Then, these complexes have been screened as catalytic precursors in the transfer hydrogenation of acetophenone with 2-propanol as both the hydrogen source and solvent in the presence of KOH. The corresponding optically active secondary alcohols were obtained in excellent conversion rates between 96 and 99% and moderate to good enantioselectivities (up to 78% ee). The complex 5 was the most efficient catalyst among the four new complexes investigated herein.Chiral C2-symmetric ferrocenyl based binuclear η6-benzene-ruthenium(II) complexes bearing diphenylphosphinite and diisopropylphosphinite moieties have been synthesised. These complexes have been screened as catalytic precursors in the transfer hydrogenation of acetophenone with 2-propanol in the presence of KOH. The corresponding optically active secondary alcohols were obtained in excellent conversion rates between 96 and 99 % and moderate to good enantioselectivities (up to 78% ee).
      PubDate: 2017-06-29T02:01:05.998308-05:
      DOI: 10.1002/aoc.3919
       
  • Ag-nanoparticle embedded p(AA) hydrogel as an efficient green
           heterogeneous Nano-catalyst for oxidation and reduction of organic
           compounds
    • Authors: Massomeh Ghorbanloo; Ali Heydari, Hidenori Yahiro
      Abstract: P(AA)-Ag heterogeneous catalyst system comprised of Ag nanoparticles embedded within hydrogel matrices has been described for the selective aerobic oxidation of alcohols and reduction of nitro phenols in water. P(AA)-Ag nanocomposite was characterized by Fourier transform infrared (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermal gravimetric analysis (TGA), X-Ray photoelectron spectroscopy (XPS) and inductively coupled plasma atomic emission spectrometer (ICP). Catalytic activity of p(AA)-Ag catalyst was investigated in the aerobic oxidation of primary alcohols and reduction of nitro compounds by emphasizing the effect of different parameters such as temperature, catalyst amount, substituent effect, etc. The catalyst was easily recovered from the reaction medium and it could be re-used for other three runs without significant loss of activity.p(AA)-Ag heterogeneous catalyst system has been described for the selective aerobic oxidation of alcohols in water. In the presence of the Ag catalyst, within 24 h and with 0.036 mmol Ag, 79% isolated yield of the benzoic acid and 1.96% yield of the benzaldehyde were obtained.
      PubDate: 2017-06-23T05:41:21.250682-05:
      DOI: 10.1002/aoc.3917
       
  • Four-, five- and six-coordinated transition metal complexes based on
           naphthalimide Schiff base ligands: Synthesis, crystal structure and
           properties
    • Authors: Yuling Xu; Han Zhang, Kesheng Shen, Shanshan Mao, Xinkui Shi, Huilu Wu
      Abstract: Two bidentate Schiff base ligands (HL1 = N-n-butyl-4-[(E)-2-(((2-aminoethyl)imino)methyl)phenol]-1,8-naphthalimide; and HL2 = N-n-butyl-4-[(E)-2-(((2-aminoethyl)imino)methyl)-6-methoxyphenol]-1,8-naphthalimide) with their metal complexes [Cu(L1)2] (1), [Zn(L1)2(Py)]2⋅H2O (2) and [Ni(L2)2(DMF)2] (3) have been synthesized and characterized. Single-crystal X-ray structure analysis reveals that complex 1 has a four-coordinated square geometry, while complex 2 is a five-coordinated square pyramidal structure and complex 3 is a distorted six-coordinated octahedral structure. Cyclic voltammograms of 1 indicate an irreversible Cu2+/Cu+ couple. In vitro antioxidant activity assay demonstrates that the ligands and the two complexes 1 and 3 display high scavenging activity against hydroxyl (HO•) and superoxide (O2−•) radicals. Moreover, the fluorescence properties of the ligands and complexes 1–3 were studied in the solid state. Metal-mediated enhancement is observed in 2, whereas metal-mediated fluorescence quenching occurs with 1 and 3.Three transition metal complexes based on naphthalimide Schiff base ligands have been synthesized and characterized systematically. The complexes and ligands have a strong potential to be applied as scavengers to eliminate radicals. Complex 2 has excellent fluorescence properties.
      PubDate: 2017-06-23T05:35:59.949943-05:
      DOI: 10.1002/aoc.3902
       
  • Claycop/hydrazine: A new and highly efficient recyclable/reusable
           catalytic system for 1,4-disubstituted-1,2,3-triazole synthesis under
           solvent-free conditions
    • Authors: Hanan M. F. Elnagdy; Kongkona Gogoi, Abdul A. Ali, Diganta Sarma
      Abstract: Clay-supported copper(II) nitrate (claycop) has been used as an efficient catalyst for azide–alkyne cycloaddition reactions leading to 1,4-disubstituted 1,2,3-triazoles. The highly efficient claycop/hydrazine hydrate catalytic system affords triazoles in a few minutes (1–20 min) at room temperature, under mild and solvent-free conditions. High regioselectivity, excellent yields, ease of claycop synthesis and recyclability/reusability of the catalyst are considered as practical merits of the protocol.A very novel method is reported where click reaction proceeds in less than a minute at room temperature under solvent-free conditions. High regioselectivity and excellent yields of triazoles in very short time are some of the important features of this methodology. The catalyst is easy to prepare and it is recyclable and reusable.
      PubDate: 2017-06-23T05:26:43.414588-05:
      DOI: 10.1002/aoc.3931
       
  • Baeyer-Villiger oxidation of cyclopentanone over zeolite Y entrapped
           transition metal-Schiff base complexes
    • Authors: Chetan K. Modi; Naresh Solanki, Ravi Vithalani, Dikin Patel
      Abstract: Transition metal [M = VO (IV) and/or Cu (II)] complexes with Schiff base ligand, (Z)-2-((2-hydroxybenzylideneamino)phenol (H2L) have been entrapped in the super cages of zeolite-Y by Flexible Ligand Method. Synthesized materials have been characterized by preferential physico-chemical techniques such as inductively coupled plasma optical emission spectroscopy (ICP-OES), elemental analyses (CHN), fourier transmission infrared spectroscopy (FTIR), electronic and UV-reflectance spectra, Brunauer–Emmett–Teller (BET) surface area measurements, scanning electron micrographs (SEMs), X-ray diffraction patterns (XRD) and thermogravimetric analysis (TGA). The catalytic competence of zeolite-Y entrapped transition metal complexes was examined in Baeyer-Villiger (BV) oxidation of cyclopentanone using 30% H2O2 as an oxidant beside neat complexes to check the aptitude of heterogeneous catalysis over the homogeneous system. The effect of experimental variables such as mole ratio of substrate to an oxidant, amount of catalyst, reaction time, varying oxidants and solvents on the conversion of cyclopentanone was also tested. Under the optimized reaction conditions, one of the zeolite-Y entrapped transition metal complex viz. [VO(L)H2O]-Y [where L = (Z)-2-((2-hydroxybenzylideneamino)phenol] was found to be a potential contender by providing 80.22% conversion of cyclopentanone (TON: 10479.42), and the selectivity towards δ-valerolactone was 83.56%.Zeolite-Y entrapped transition metal complexes were examined to check the catalytic competence for Baeyer-Villiger (BV) oxidation of cyclopentanone using 30% H2O2 as an oxidant. Amongst them, optimal performance attained by [VO(L)H2O]-Y catalyst with 80.22% conversion of cyclopentanone and 83.56% selectivity towards δ-valerolactone.
      PubDate: 2017-06-19T00:10:35.460311-05:
      DOI: 10.1002/aoc.3910
       
  • Mesoporous silica SBA-15 functionalized with acidic deep eutectic solvent:
           A highly active heterogeneous N-formylation catalyst under solvent-free
           conditions
    • Authors: Najmedin Azizi; Mahtab Edrisi, Faezeh Abbasi
      Abstract: Mesoporous silica SBA-15 functionalized with N-methylpyrrolidonium-zinc chloride based deep eutectic solvent (DES) is found to be a more efficient and reusable catalyst for a convenient N-formylation of a variety of amines at room temperature. N-Formylation of primary, secondary as well as heterocyclic amines have been carried out in good to excellent yields by treatment with formic acid in low loading of DES/SBA-15 an environmentally benign catalyst for the first time. The DES/SBA-15 catalyst, which possesses both Brønsted and Lewis acidities as well as an active SBA-15 support, makes this procedure quite simple, reusable, more convenient and practical. This catalyst was tolerant of a wide range of functional groups, and it can be reused for four runs without obvious deactivation.DES/SBA-15 an attractive nanocomposite, was employed as a more efficient and reusable catalyst for a convenient N-formylation of a variety of amines. Various primary, secondary as well as heterocyclic amines were tested and proved successful using this green methodology under mild reaction condition. This nanocomposite was tolerant of a wide range of functional groups, and it can be reused for four runs without obvious deactivation.
      PubDate: 2017-06-19T00:06:01.673305-05:
      DOI: 10.1002/aoc.3901
       
  • Efficient and selective oxidation of alcohols in water employing palladium
           supported nanomagnetic Fe3O4@hyperbranched polyethylenimine
           (Fe3O4@HPEI.Pd) as a new organic–inorganic hybrid nanocatalyst
    • Authors: Ali Ramazani; Mehdi Khoobi, Fariba Sadri, Roghayeh Tarasi, Abbas Shafiee, Hamideh Aghahosseini, Sang Woo Joo
      Abstract: Palladium immobilized magnetic nanoFe3O4@hyperbranched polyethylenimine (Fe3O4@HPEI.Pd) was prepared according to a simple and cost effective pathway and it was employed as a new efficient and selective organic–inorganic hybrid nanocatalyst for the aqueous oxidation of primary and secondary alcohols to their corresponding products in good yields applying oxone (potassium hydrogen monopersulfate) and H2O2 as an oxidant at room temperature. Moreover, the catalytic system was reused at least 13 times without significant loss of activity. The complete characterization of this efficient nanocatalyst was investigated by FTIR, UV–Vis, TEM, SEM, XRD, TGA, VSM, ICP and EDX techniques.Modifying the surfaces of Fe3O4 with the blend of hyperbranched polyethylenimine (HPEI) and [3-(2,3-epoxypropoxy)propyl]trimethoxysilane (EPO), then the adsorption of Pd inside its shell to produce fe3o4@hpei.pd, as an active, stable, and reusable catalyst for the selective oxidation of alcohols.
      PubDate: 2017-06-13T03:50:52.729174-05:
      DOI: 10.1002/aoc.3908
       
  • Buchwald-Hartwig amination reaction of aryl halides using heterogeneous
           catalyst based on Pd nanoparticles decorated on chitosan functionalized
           graphene oxide
    • Authors: Mosayeb Sarvestani; Roya Azadi
      Abstract: In this work, graphene oxide was functionalized with chitosan (GO-Chit) followed by a simple approach for immobilization of palladium nanoparticles onto a chitosan grafted graphene oxide surface. The Pd-nanocomposite (GO-Chit-Pd) was characterized using Transmission Electron Microscopy (TEM), Fourier transforms infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) measurements. The catalytic activity of the prepared heterogeneous graphene oxide functionalized chitosan-palladium (GO-Chit-Pd) was investigated in term of C-N coupling reaction (Buchwald-Hartwig amination reaction of aryl halides) yielding products of N-arylamines. The easy purification, convenient operation, and environmental friendliness, combined with a high yield, render this method viable for use in both laboratory research and larger industrial scales. Studying the reusability of the catalyst in this work showed that it could be reused for five times without obvious loss in catalytic activity.Graphene oxide was functionalized with chitosan (GO-Chit) followed by a simple approach for immobilization of palladium nanoparticles onto a chitosan grafted graphene oxide surface. The catalytic activity of the prepared heterogeneous graphene oxide functionalized chitosan-palladium (GO-Chit-Pd) was investigated in term of C-N coupling reaction (Buchwald-Hartwig amination reaction of aryl halides) yielding products of N-arylamines.
      PubDate: 2017-06-13T03:31:07.824221-05:
      DOI: 10.1002/aoc.3906
       
  • Synthesis, characterization and biological properties of mixed ligand
           complexes of cobalt(II/III) valproate with
           2,9-dimethyl-1,10-phenanthroline and 1,10-phenanthroline
    • Authors: Amani Abu Shamma; Hijazi Abu Ali, Shayma Kamel
      Abstract: The synthesis of mononuclear cobalt(II/III) complexes with two different ligands (complex 2: [Co(valp)2(2,9-dmp)] and complex 3: [Co(valp)2(H2O)(1,10-phen)]) was investigated and the characterization of both complexes was achieved using IR, UV–Vis, and single crystal X-ray diffraction. Using single crystal X-ray diffraction, the crystal structure of each of the complexes was determined. Additionally, the biological activity of these complexes was studied in five gram-positive and four gram-negative bacterial strains. Whereas in all gram-negative bacteria tested, cobalt valproate complexes did not show any anti-bacterial activity, both complexes had effects on gram positive bacteria. Complex 2 demonstrated good anti-bacterial activity against all gram-positive bacteria with inhibition zone diameter (IZD) ranging between 15–28 mm. Complex 3 exhibited low inhibition activity against all gram-positive bacteria except E. faecalis with IZD ranging between 11.3–13.7 mm. Moreover, as an indication of its uses as industrial catalyst, the rate of bis(p-nitrophenyl) phosphate (BNPP) hydrolysis when catalyzed by these complexes was measured at different temperatures, concentrations and pH. Complex 2 proved to be a better catalyst to induce the hydrolysis of BNPP.BNPP hydrolysis by complex 2 in MeOH /HEPEs buffer solution with different pH values under the selected conditions (T = 25 °C, [complex 2] = 2 × 10−3 M and [BNPP] = 1 × 10−4 M).
      PubDate: 2017-06-07T03:35:45.51204-05:0
      DOI: 10.1002/aoc.3904
       
  • Efficient and green catalytic system incorporating new benzimidazolium
           salts for the Sonogashira cross-coupling reaction
    • Authors: Kemal Yavuz; Hasan Küçükbay
      Abstract: A number of novel benzimidazole salts were synthesized and their structures were determined using 1H NMR, 13C NMR and infrared spectroscopic techniques and elemental analysis. A catalyst system consisting of Pd(OAc)2 and copper nanoparticles in the presence of Cs2CO3 and incorporating the novel benzimidazole salts in poly(ethylene glycol) solvent significantly improved the yields of Sonogashira reactions between aryl halides and phenylacetylene under microwave irradiation in 10 min.We have developed an efficient, simple and environmentally benign catalytic system incorparating novel benzimidazole salts for the Sonogashira cross coupling reaction.the catalyst system consisting of Pd(OAc)2, CuNPc, benzimidazole salts, Cs2CO3 in PEG300 can be recycled at least tree times without loss of activity in short reaction time (10 min) without any palladium black formation.
      PubDate: 2017-06-07T03:20:55.860566-05:
      DOI: 10.1002/aoc.3897
       
  • A new azo-Schiff base: Synthesis, characterization, biological activity
           and theoretical studies of its complexes
    • Authors: Wail Al Zoubi; Abbas Ali Salih Al-Hamdani, Susan Duraid Ahmed, Young Gun Ko
      Abstract: A new Azo-Schiff base ligand L was prepared by reaction of m-hydroxy benzoic acid with (Schiff base B) of 3-[2-(1H–indol-3-yl)-ethylimino]-1.5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamine. This synthesized ligand was used for complexation with different metal ions like Ni(II), Co(II), Pd(II) and Pt(IV) by using a molar ratio of ligand: metal as 1:1. Resulted compounds were characterized by NMR (1H and 13C), UV–vis spectroscopy, TGA, FT-IR, MS, elemental analysis, magnetic moment and molar conductivity studies. The activation thermodynamic parameters, such as ΔE*, ΔH*, ΔS*, ΔG*and K are calculated from the TGA curves using Coats-Redfern method. Hyper Chem-8 program has been used to predict structural geometries of compounds in gas phase. The biological activities of Schiff base and its complexes had been tested in vitro against, two Gram positive bacteria (Bacillus subtillis and Staphylococcus aureus) and two Gram negative bacteria (Escherichia coli and Pseudomonas aeruguinosa).Prepared ligand was used for complexation with different metal cations like Ni(II), Co(II), Pd(II) and Pt(IV) by using a molar ratio of ligand: metal as 1:1. These complexes were characterized by NMR (1H and 13C), UV–vis spectroscopy, TGA, FT-IR, MS, elemental analysis, magnetic moment and molar conductivity studies. Biological activities of Schiff base complexes had been tested in vitro against, two Gram positive bacteria (Bacillus subtillis and Staphylococcus aureus) and two Gram negative bacteria (Escherichia coli and Pseudomonas aeruguinosa).
      PubDate: 2017-06-02T04:01:01.217664-05:
      DOI: 10.1002/aoc.3895
       
  • Polymer-supported palladium: A hybrid system for multifunctional catalytic
           application
    • Authors: Abu Taher; Meenakshi Choudhary, Debkumar Nandi, Samarjeet Siwal, Kaushik Mallick
      Abstract: Polymer-supported palladium was synthesized by applying a single-step wet chemical synthesis route and the resultant composite material was characterized by means of various techniques. Infrared and UV–visible spectra provided information on the chemical structure of the polymer. Microscopy techniques showed the general morphology of the polymer. The oxidation state of palladium was determined using the X-ray photoelectron spectroscopy method. The synthesized material was applied as a heterogeneous catalyst for the Heck coupling reaction and also as an electrocatalyst for the oxidation of cysteine.Multifunctional polymer supported palladium catalyst for the (a) Heck coupling reaction and (b) electrochemical cysteine oxidation.
      PubDate: 2017-05-30T22:15:44.959558-05:
      DOI: 10.1002/aoc.3898
       
  • Bis-benzimidazolium-palladium system catalyzed Suzuki-Miyaura coupling
           reaction of aryl bromides under mild conditions
    • Authors: Yi-Rang Lin; Chien-Cheng Chiu, Huai-Tsu Chiu, Dong-Sheng Lee, Ta-Jung Lu
      Abstract: Bis-benzimidazolium salts were prepared successfully from commercially available and inexpensive o-phenylenediamine through a series of simple reactions. The bis-NHC-Pd complexes prepared in situ can catalyze Suzuki-Miyaura cross-coupling reaction under very mild conditions in aqueous media with excellent yields. The efficiency of this reaction is demonstrated by its compatibility with a range of functional groups. Di-ortho-substituted biaryls could be accomplished in 89–99% yields. Moreover, the rigorous exclusion of air or moisture is not required in these transformations.The bis-NHC-Pd complexes prepared in situ can catalyze Suzuki-Miyaura cross-coupling reaction under mild conditions in aqueous media with excellent yields. The efficiency of this reaction is demonstrated by its compatibility with a wide range of functional groups. Di-ortho-substituted biaryls could be accomplished in 89–99% yields.
      PubDate: 2017-05-30T22:10:48.44626-05:0
      DOI: 10.1002/aoc.3896
       
  • Hydrothermal preparation and characterization of ZnFe2O4 magnetic
           nanoparticles as an efficient heterogeneous catalyst for the synthesis of
           multi-substituted imidazoles and study of their anti-inflammatory activity
           
    • Authors: Adel A. Marzouk; Ahmed M. Abu-Dief, Antar A. Abdelhamid
      Abstract: Nanoparticles are key focus of research for a wide range of novel applications. As such, ZnFe2O4 magnetic nanoparticles were synthesized hydrothermally and characterized via scanning and transmission electron microscopies, powder X-ray diffraction, energy-dispersive X-ray and infrared spectroscopies, thermogravimetric analysis and magnetic measurements. They were used as a robust catalyst for the synthesis of a series of biologically active multi-substituted imidazoles using a multicomponent reaction by the reaction of benzil with various aromatic aldehydes, ammonium acetate and aliphatic amines (N,N-dimethyl-1,3-propanediamine and 1-amino-2-propanol) under solvent-free conditions. The key advantages of this method are shorter reaction times, very high yield and ease of operation. The thermally and chemically stable, benign and economical catalyst was easily recovered using an external magnet and reused in at least five successive runs without an appreciable loss of activity. All of these novel synthesized compounds were characterized from spectral data and their purities were checked using thin-layer chromatography, giving one spot. Furthermore, the prepared compounds were tested for their anti-inflammatory activity.ZnFe2O4 magnetic nanoparticles was synthesized hydrothermally and characterized via SEM, TEM, HR-TEM, powder X-ray, EDAX, IR, TGA as well as magnetic measurements. Moreover, they were used as a robust catalyst for the synthesis of a series of biologically active multi-substituted imidazoles using a multicomponent reaction. Furthermore, the prepared multi-substituted imidazoles were tested for their anti-inflammatory activity.
      PubDate: 2017-04-10T01:57:41.181615-05:
      DOI: 10.1002/aoc.3794
       
 
 
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