JournalTOCs

Communications Chemistry
Number of Followers: 2

This is an Open Access Journal

Open Access journal
ISSN (Online) 2399-3669
Published by NPG

[138 journals]

Electropolymerization without an electric power supply
- Communications Chemistry, Published online: 27 May 2022; doi:10.1038/s42004-022-00682-8
  Electrochemical synthesis has become a powerful tool, but the need for an electric power supply has disadvantages when considering sustainable development goals. Here, a streaming potential generated by a laminar flow of electrolyte in a microchannel acts as a driving force for electrode reactions, enabling electrochemical oxidative polymerization of aromatic monomers without an electric power supply.Communications Chemistry, Published online: 2022-05-27; doi:10.1038/s42004-022-00682-82022-05-27
  DOI: 10.1038/s42004-022-00682-8
Constructing rapid water vapor transport channels within mixed matrix
membranes based on two-dimensional mesoporous nanosheets
- Communications Chemistry, Published online: 24 May 2022; doi:10.1038/s42004-022-00681-9
  Gas dehumidification with permeable membranes is typically a technique low in operating costs and environmental impact, making it preferable over condensation or adsorption methods, but membrane permeability and selectivity remain a trade-off. Here, the authors use cerium fluoride oxide mesoporous nanosheets in the ionic liquid [Emim][DCA] as a filler in the polyether block amide PEBAX to achieve a mixed matrix membrane with a water vapour permeability of 4.53 × 105 Barrer and a H2O/N2 selectivity of 1.69 × 105.Communications Chemistry, Published online: 2022-05-24; doi:10.1038/s42004-022-00681-92022-05-24
  DOI: 10.1038/s42004-022-00681-9
Targeting undruggable carbohydrate recognition sites through focused
fragment library design
- Communications Chemistry, Published online: 20 May 2022; doi:10.1038/s42004-022-00679-3
  Carbohydrate–protein interactions are key for cell–cell and host–pathogen recognition, but their hydrophilic nature makes the development of drug-like inhibitors a challenge. Here, screening of fragment libraries identifies metal-binding pharmacophores as novel scaffolds for the inhibition of Ca2+-dependent carbohydrate–protein interactions.Communications Chemistry, Published online: 2022-05-20; doi:10.1038/s42004-022-00679-32022-05-20
  DOI: 10.1038/s42004-022-00679-3
Iridium-catalyzed enantioselective synthesis of chiral γ-amino alcohols
and intermediates of (S)-duloxetine, (R)-fluoxetine, and (R)-atomoxetine
- Communications Chemistry, Published online: 19 May 2022; doi:10.1038/s42004-022-00678-4
  Enantioselective hydrogenation of β-amino ketones is a powerful tool to produce bioactive molecules, but their asymmetric transformation is synthetically challenging. Here, an iridium-catalysed system with tridentate ferrocene-based phosphine ligands bearing unsymmetrical vicinal diamine scaffolds is developed for the efficient asymmetric synthesis of diverse γtertiary-amino and γ-secondary-amino alcohols, including intermediates of (S)-duloxetine, (R)-fluoxetine and (R)-atomoxetine.Communications Chemistry, Published online: 2022-05-19; doi:10.1038/s42004-022-00678-42022-05-19
  DOI: 10.1038/s42004-022-00678-4
A chemical link between methylamine and methylene imine and implications
for interstellar glycine formation
- Communications Chemistry, Published online: 12 May 2022; doi:10.1038/s42004-022-00677-5
  The detection of glycine in comets is suggestive of a cosmic origin for amino acids on Earth, but the formation of glycine in interstellar media remains poorly understood. Here, infrared spectroscopy shows that the CH2NH2 radical can be formed from H + CH3NH2 in conditions relevant to dark interstellar clouds, supporting the proposal that glycine could be formed from the reaction of CH2NH2 and HOCO radicals.Communications Chemistry, Published online: 2022-05-12; doi:10.1038/s42004-022-00677-52022-05-12
  DOI: 10.1038/s42004-022-00677-5
Supercritical fluid chromatography-mass spectrometry enables simultaneous
measurement of all phosphoinositide regioisomers
- Communications Chemistry, Published online: 11 May 2022; doi:10.1038/s42004-022-00676-6
  Phosphoinositide (PIP) species play important roles in a number of cellular events, but the simultaneous quantification of individual PIP species remains challenging using conventional methods. Here, the authors report a supercritical fluid chromatography-mass spectrometry approach to simultaneous measure the molecular species of all seven PIP regioisomers.Communications Chemistry, Published online: 2022-05-11; doi:10.1038/s42004-022-00676-62022-05-11
  DOI: 10.1038/s42004-022-00676-6
Thiazol-2-ylidenes as N-Heterocyclic carbene ligands with enhanced
electrophilicity for transition metal catalysis
- Communications Chemistry, Published online: 06 May 2022; doi:10.1038/s42004-022-00675-7
  N-heterocyclic carbenes are widely exploited as ligands in transition metal catalysis, but are largely limited to N-arylimidazolylidenes. Here, the authors report on the steric and electronic properties of thiazol-2-ylidenes, demonstrating that their enhanced π-electrophilicity makes them attractive as carbene ligands in transition metal-catalysed electrophilic cyclization reactions.Communications Chemistry, Published online: 2022-05-06; doi:10.1038/s42004-022-00675-72022-05-06
  DOI: 10.1038/s42004-022-00675-7
Pre-arranged building block approach for the orthogonal synthesis of an
unfolded tetrameric organic–inorganic phosphazane macrocycle
- Communications Chemistry, Published online: 05 May 2022; doi:10.1038/s42004-022-00673-9
  Hybrid organic–inorganic phosphazane macrocycles have been studied for their potentially useful host–guest chemistries, but synthetic routes capable of controlling their size have yet to be reported. Here, a two-step route that exploits pre-arranged building blocks enables the design of an unfolded tetrameric macrocycle.Communications Chemistry, Published online: 2022-05-05; doi:10.1038/s42004-022-00673-92022-05-05
  DOI: 10.1038/s42004-022-00673-9