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  Subjects -> CHEMISTRY (Total: 849 journals)
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CHEMISTRY (598 journals)                  1 2 3 | Last

Showing 1 - 200 of 735 Journals sorted alphabetically
2D Materials     Hybrid Journal   (Followers: 8)
Accreditation and Quality Assurance: Journal for Quality, Comparability and Reliability in Chemical Measurement     Hybrid Journal   (Followers: 26)
ACS Catalysis     Full-text available via subscription   (Followers: 32)
ACS Chemical Neuroscience     Full-text available via subscription   (Followers: 17)
ACS Combinatorial Science     Full-text available via subscription   (Followers: 23)
ACS Macro Letters     Full-text available via subscription   (Followers: 23)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
ACS Nano     Full-text available via subscription   (Followers: 227)
ACS Photonics     Full-text available via subscription   (Followers: 11)
ACS Synthetic Biology     Full-text available via subscription   (Followers: 21)
Acta Chemica Iasi     Open Access   (Followers: 2)
Acta Chimica Sinica     Full-text available via subscription   (Followers: 1)
Acta Chimica Slovaca     Open Access   (Followers: 1)
Acta Chromatographica     Full-text available via subscription   (Followers: 9)
Acta Facultatis Medicae Naissensis     Open Access  
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5)
Acta Scientifica Naturalis     Open Access   (Followers: 2)
adhäsion KLEBEN & DICHTEN     Hybrid Journal   (Followers: 5)
Adhesion Adhesives & Sealants     Hybrid Journal   (Followers: 7)
Adsorption Science & Technology     Full-text available via subscription   (Followers: 5)
Advanced Functional Materials     Hybrid Journal   (Followers: 50)
Advanced Science Focus     Free   (Followers: 3)
Advances in Chemical Engineering and Science     Open Access   (Followers: 53)
Advances in Chemical Science     Open Access   (Followers: 13)
Advances in Chemistry     Open Access   (Followers: 14)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Enzyme Research     Open Access   (Followers: 9)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 15)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8)
Advances in Materials Physics and Chemistry     Open Access   (Followers: 19)
Advances in Nanoparticles     Open Access   (Followers: 14)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15)
Advances in Polymer Science     Hybrid Journal   (Followers: 41)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 19)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Science and Technology     Full-text available via subscription   (Followers: 12)
African Journal of Bacteriology Research     Open Access  
African Journal of Chemical Education     Open Access   (Followers: 2)
African Journal of Pure and Applied Chemistry     Open Access   (Followers: 7)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Journal of Biochemistry and Biotechnology     Open Access   (Followers: 67)
American Journal of Biochemistry and Molecular Biology     Open Access   (Followers: 14)
American Journal of Chemistry     Open Access   (Followers: 26)
American Journal of Plant Physiology     Open Access   (Followers: 13)
American Mineralogist     Hybrid Journal   (Followers: 13)
Analyst     Full-text available via subscription   (Followers: 38)
Angewandte Chemie     Hybrid Journal   (Followers: 158)
Angewandte Chemie International Edition     Hybrid Journal   (Followers: 208)
Annales UMCS, Chemia     Open Access   (Followers: 1)
Annals of Clinical Chemistry and Laboratory Medicine     Open Access   (Followers: 1)
Annual Reports in Computational Chemistry     Full-text available via subscription   (Followers: 3)
Annual Reports Section A (Inorganic Chemistry)     Full-text available via subscription   (Followers: 3)
Annual Reports Section B (Organic Chemistry)     Full-text available via subscription   (Followers: 8)
Annual Review of Chemical and Biomolecular Engineering     Full-text available via subscription   (Followers: 12)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 14)
Anti-Infective Agents     Hybrid Journal   (Followers: 3)
Antiviral Chemistry and Chemotherapy     Hybrid Journal  
Applied Organometallic Chemistry     Hybrid Journal   (Followers: 7)
Applied Spectroscopy     Full-text available via subscription   (Followers: 23)
Applied Surface Science     Hybrid Journal   (Followers: 28)
Arabian Journal of Chemistry     Open Access   (Followers: 6)
ARKIVOC     Open Access   (Followers: 2)
Asian Journal of Biochemistry     Open Access   (Followers: 1)
Atomization and Sprays     Full-text available via subscription   (Followers: 3)
Australian Journal of Chemistry     Hybrid Journal   (Followers: 7)
Autophagy     Hybrid Journal   (Followers: 2)
Avances en Quimica     Open Access   (Followers: 1)
Biochemical Pharmacology     Hybrid Journal   (Followers: 10)
Biochemistry     Full-text available via subscription   (Followers: 283)
Biochemistry Insights     Open Access   (Followers: 5)
Biochemistry Research International     Open Access   (Followers: 6)
BioChip Journal     Hybrid Journal  
Bioinorganic Chemistry and Applications     Open Access   (Followers: 9)
Bioinspired Materials     Open Access   (Followers: 5)
Biointerface Research in Applied Chemistry     Open Access   (Followers: 2)
Biointerphases     Open Access   (Followers: 1)
Biology, Medicine, & Natural Product Chemistry     Open Access   (Followers: 1)
Biomacromolecules     Full-text available via subscription   (Followers: 19)
Biomass Conversion and Biorefinery     Partially Free   (Followers: 10)
Biomedical Chromatography     Hybrid Journal   (Followers: 6)
Biomolecular NMR Assignments     Hybrid Journal   (Followers: 3)
BioNanoScience     Partially Free   (Followers: 4)
Bioorganic & Medicinal Chemistry     Hybrid Journal   (Followers: 108)
Bioorganic & Medicinal Chemistry Letters     Hybrid Journal   (Followers: 93)
Bioorganic Chemistry     Hybrid Journal   (Followers: 10)
Biopolymers     Hybrid Journal   (Followers: 18)
Biosensors     Open Access   (Followers: 2)
Biotechnic and Histochemistry     Hybrid Journal   (Followers: 1)
Bitácora Digital     Open Access  
Boletin de la Sociedad Chilena de Quimica     Open Access  
Bulletin of the Chemical Society of Ethiopia     Open Access   (Followers: 2)
Bulletin of the Chemical Society of Japan     Full-text available via subscription   (Followers: 24)
Bulletin of the Korean Chemical Society     Hybrid Journal   (Followers: 1)
C - Journal of Carbon Research     Open Access   (Followers: 3)
Cakra Kimia (Indonesian E-Journal of Applied Chemistry)     Open Access  
Canadian Association of Radiologists Journal     Full-text available via subscription   (Followers: 2)
Canadian Journal of Chemistry     Hybrid Journal   (Followers: 10)
Canadian Mineralogist     Full-text available via subscription   (Followers: 3)
Carbohydrate Research     Hybrid Journal   (Followers: 26)
Carbon     Hybrid Journal   (Followers: 67)
Catalysis for Sustainable Energy     Open Access   (Followers: 6)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 6)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysts     Open Access   (Followers: 7)
Cellulose     Hybrid Journal   (Followers: 7)
Cereal Chemistry     Full-text available via subscription   (Followers: 4)
ChemBioEng Reviews     Full-text available via subscription   (Followers: 1)
ChemCatChem     Hybrid Journal   (Followers: 8)
Chemical and Engineering News     Free   (Followers: 12)
Chemical Bulletin of Kazakh National University     Open Access  
Chemical Communications     Full-text available via subscription   (Followers: 70)
Chemical Engineering Research and Design     Hybrid Journal   (Followers: 23)
Chemical Research in Chinese Universities     Hybrid Journal   (Followers: 3)
Chemical Research in Toxicology     Full-text available via subscription   (Followers: 19)
Chemical Reviews     Full-text available via subscription   (Followers: 170)
Chemical Science     Open Access   (Followers: 21)
Chemical Technology     Open Access   (Followers: 16)
Chemical Vapor Deposition     Hybrid Journal   (Followers: 5)
Chemical Week     Full-text available via subscription   (Followers: 8)
Chemie in Unserer Zeit     Hybrid Journal   (Followers: 55)
Chemie-Ingenieur-Technik (Cit)     Hybrid Journal   (Followers: 25)
ChemInform     Hybrid Journal   (Followers: 8)
Chemistry & Biodiversity     Hybrid Journal   (Followers: 6)
Chemistry & Biology     Full-text available via subscription   (Followers: 30)
Chemistry & Industry     Hybrid Journal   (Followers: 5)
Chemistry - A European Journal     Hybrid Journal   (Followers: 144)
Chemistry - An Asian Journal     Hybrid Journal   (Followers: 15)
Chemistry and Materials Research     Open Access   (Followers: 18)
Chemistry Central Journal     Open Access   (Followers: 4)
Chemistry Education Research and Practice     Free   (Followers: 5)
Chemistry in Education     Open Access   (Followers: 9)
Chemistry International     Hybrid Journal   (Followers: 2)
Chemistry Letters     Full-text available via subscription   (Followers: 45)
Chemistry of Materials     Full-text available via subscription   (Followers: 226)
Chemistry of Natural Compounds     Hybrid Journal   (Followers: 9)
Chemistry World     Full-text available via subscription   (Followers: 22)
Chemistry-Didactics-Ecology-Metrology     Open Access  
ChemistryOpen     Open Access   (Followers: 2)
Chemkon - Chemie Konkret, Forum Fuer Unterricht Und Didaktik     Hybrid Journal  
Chemoecology     Hybrid Journal   (Followers: 2)
Chemometrics and Intelligent Laboratory Systems     Hybrid Journal   (Followers: 15)
Chemosensors     Open Access  
ChemPhysChem     Hybrid Journal   (Followers: 9)
ChemPlusChem     Hybrid Journal   (Followers: 2)
ChemTexts     Hybrid Journal  
CHIMIA International Journal for Chemistry     Full-text available via subscription   (Followers: 2)
Chinese Journal of Chemistry     Hybrid Journal   (Followers: 6)
Chinese Journal of Polymer Science     Hybrid Journal   (Followers: 10)
Chromatographia     Hybrid Journal   (Followers: 24)
Chromatography Research International     Open Access   (Followers: 7)
Clay Minerals     Full-text available via subscription   (Followers: 9)
Cogent Chemistry     Open Access  
Colloid and Interface Science Communications     Open Access  
Colloid and Polymer Science     Hybrid Journal   (Followers: 10)
Colloids and Surfaces B: Biointerfaces     Hybrid Journal   (Followers: 8)
Combinatorial Chemistry & High Throughput Screening     Hybrid Journal   (Followers: 3)
Combustion Science and Technology     Hybrid Journal   (Followers: 18)
Comments on Inorganic Chemistry: A Journal of Critical Discussion of the Current Literature     Hybrid Journal   (Followers: 2)
Composite Interfaces     Hybrid Journal   (Followers: 6)
Comprehensive Chemical Kinetics     Full-text available via subscription   (Followers: 2)
Comptes Rendus Chimie     Full-text available via subscription  
Comptes Rendus Physique     Full-text available via subscription   (Followers: 1)
Computational and Theoretical Chemistry     Hybrid Journal   (Followers: 9)
Computational Biology and Chemistry     Hybrid Journal   (Followers: 12)
Computational Chemistry     Open Access   (Followers: 2)
Computers & Chemical Engineering     Hybrid Journal   (Followers: 9)
Coordination Chemistry Reviews     Full-text available via subscription   (Followers: 2)
Copernican Letters     Open Access  
Critical Reviews in Biochemistry and Molecular Biology     Hybrid Journal   (Followers: 5)
Crystal Structure Theory and Applications     Open Access   (Followers: 3)
CrystEngComm     Full-text available via subscription   (Followers: 11)
Current Catalysis     Hybrid Journal   (Followers: 2)
Current Metabolomics     Hybrid Journal   (Followers: 5)
Current Opinion in Colloid & Interface Science     Hybrid Journal   (Followers: 9)
Current Research in Chemistry     Open Access   (Followers: 8)
Current Science     Open Access   (Followers: 56)
Dalton Transactions     Full-text available via subscription   (Followers: 20)
Detection     Open Access   (Followers: 2)
Developments in Geochemistry     Full-text available via subscription   (Followers: 2)
Diamond and Related Materials     Hybrid Journal   (Followers: 12)
Dislocations in Solids     Full-text available via subscription  
Doklady Chemistry     Hybrid Journal  
Drying Technology: An International Journal     Hybrid Journal   (Followers: 4)
Eclética Química     Open Access   (Followers: 1)
Ecological Chemistry and Engineering S     Open Access   (Followers: 4)
Ecotoxicology and Environmental Contamination     Open Access  
Educación Química     Open Access   (Followers: 1)
Education for Chemical Engineers     Hybrid Journal   (Followers: 5)
EJNMMI Radiopharmacy and Chemistry     Open Access  
Elements     Full-text available via subscription   (Followers: 2)
Environmental Chemistry     Hybrid Journal   (Followers: 9)
Environmental Chemistry Letters     Hybrid Journal   (Followers: 4)
Environmental Science & Technology Letters     Full-text available via subscription   (Followers: 5)

        1 2 3 | Last

Journal Cover Cakra Kimia (Indonesian E-Journal of Applied Chemistry)
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   ISSN (Online) 2302-7274
   Published by Universitas Udayana Homepage  [28 journals]
  • ANALISIS LOGAM Cd (II) DENGAN METODE VOLTAMETRI PELUCUTAN ANODIK
           MENGGUNAKAN ELEKTRODA PASTA KARBON TERMODIFIKASI ZEOLIT ALAM

    • Authors: Irdhawati Irdhawati, Ni Ketut Esati, Hery Suyanto
      Pages: 94 - 102
      Abstract: Pada penelitian ini telah dipelajari material zeolit alam teraktivasi asam sulfat 0,1 M yang digunakan sebagai modifier dalam elektroda kerja pasta karbon (EPK). Kinerja EPK termodifikasi zeolit alam teraktivasi asam (EPKZA) dibandingkan dengan EPK tanpa modifier dan penerapannya dalam penentuan kadar logam Cd(II) dalam sampel sayur dengan metode voltametri pelucutan anodik. Parameter optimasi yang diuji meliputi waktu deposisi dan laju pindai pada EPK dan EPKZA, serta komposisi zeolit dalam EPKZA. Komposisi elektroda kerja terbaik pada kondisi optimum pengukuran digunakan untuk menentukan rentang konsentrasi linier, limit deteksi, ketelitian, dan ketepatan penentuan logam Cd(II). Hasil yang diperoleh yaitu waktu deposisi 630 detikdan laju pindai 10 mV/s menggunakan EPK, dan komposisi modifier terbaik sebesar 5% dalam EPKZA, dengan waktu deposisi  540 detik dan laju pindai 20 mV/s. Rentang konsentrasi pengukuran EPKZA lebih luas yaitu dari 50-2000 ppb, sedangkan EPK tanpa modifier hanya memiliki rentang konsentrasi dari 100-1000 ppb. EPKZA dapat mengukur logam dengan konsentrasi yang lebih rendah dari EPK tanpa modifier, dengan batas deteksi pengukuran EPKZA adalah 58,41 ppb, sedangkan batas deteksi pengukuran EPK tanpa modifier sebesar 94,38 ppb. Keberulangan pengukuran larutan standar logamCd(II) dengan EPKZA menghasilkan nilai HorRat yang lebih kecil dari dua, serta nilai persen perolehan kembali sebesar 99,28±3,12 %, sehingga metode ini memiliki keseksamaan dan akurasi yang sangat baik. In this research the natural zeolite material activated by 0.1 M sulfuric acid was used as a modifier for carbon paste electrode (CPE). The performance of CPE modified by acid activated natural zeolite (CPEZ) was compared with CPE without modifier one and applied in the determination of Cd(II) concentration in vegetable samples using anodic stripping voltammetry method. The observed parameters includes deposition time and scan rate at CPE and CPEZ, and composition of modifier in CPEZ. The optimum composition and measurement condition of working electrode was used for determination linear range concentration, limit of detection, repeatability, and percent recovery. The result shows that the optimum deposition time are 630 s and 540 s, and scan rates are 10 mV/s and 20 mV/s for CPE and CPEZ respectively with the modifier concentration of 5%. The linear range concentration for CPEZ observed at 50-2000 ppb has wider range than CPE which was 100-1000 ppb. Limit of detection of CPEZ of 58.41 ppb is lower than CPE of 94.38 ppb. Determination of repeatability measurement of Cd(II) solution has HorRat value less than two, and percent recovery is 99.28+3.12%. Therefore, this method has a very good precision and accuracy.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • POTENSI ZAT AKTIF ANTIKANKER SOLASODIN TERENKAPUSULASI PADA ZEOLIT
           KLINOPTILOLIT SEBAGAI SISTEM PENGANTAR OBAT (DRUG DELIVERY SYSTEM)

    • Authors: I Made Wisnu Adhi Putra, I Gede Mustika
      Pages: 103 - 112
      Abstract: Sistem penghantar obat merupakan formulasi obat atau alat yang memungkinkan pemasukan obat ke dalam tubuh dan meningkatkan kemanjuran dan keamanan obat dengan mengontrol laju, waktu, dan situs lepas obat di dalam tubuh. Dalam penelitian ini, sistem penghantar obat dibuat dengan enkapsulasi senyawa aktif antikanker solasodin (SSD) pada zeolit klinoptilolit (CLI) dengan variasi konsentrasi larutan awal solasodin. Sistem penghantar obat hasil sintesis dikarakterisasi menggunakan FTIR, XRD dan N2 sorption analyzer. Jumlah solasodin terenkapsulasi dihitung menggunakan metode gravimetri sederhana. Hasil karakterisasi menggunakan FTIR menunjukkan tidak terjadi perubahan gugus fungsi pada zeolit ketika solasodin dienkapsulasi. Hasil XRD juga menyatakan bahwa tidak terjadi perubahan struktur kristal pada zeolit karena enkapsualasi solasodin. Luas permukaan zeolit ditemukan menurun ketika solasodin terenkapsulasi. Enkapsulasi solasodin pada zeolit klinoptilolit secara optimum terjadi pada pH 9. Jumlah solasodin terenkapsulasi secara maksimum terjadi pada konsentrasi larutan awal solasodin 250 mg/L. Uji in vitro menunjukkan bahwa pelepasan solasodin tidak terjadi pada cairan lambung simulasi (pH 1,2) selama 12 jam. Pada cairan usus simulasi (pH 7,4), solasodin perlahan-lahan lepas pada 4 jam pertama, meningkat drastis pada jam ke-5, dan menurun perlahan-lahan pada jam ke-6 sampai jam ke-12. Drug delivery system (DDS) is drug formulation or device that allows the drugs administration within the body and increases drug efficacy and safety by controlling drugs rate, time, and release sites in the body. In this research, we made drug delivery systems by encapsulating anticancer active compound solasodine (SSD) into clinoptilolite zeolite (CLI) with the variation of initial concentration of solasodine. The as-synthetized drug delivery systems were then characterized by using FTIR, XRD and N2 sorption analyzer. The amount of solasodine encapsulated on zeolite was calculated by using simple gravimetric method. FTIR results showed that there were no alteration in functional groups of zeolite when solasodine encapsulated into zeolite. XRD results also confirmed that there were no zeolite crystalline structure changes after the encapsulation of solasodine. Surface area of zeolite was found to decrease as the solasodine encapsulated into zeolites. Based on the effect of pH test, it was found that the maximum amount of solasodine encapsulated into zeolite structure was occurred at pH of 9. Meanwhile, the encapsulation of solasodine in various concentrations reached the maximum at the concentration of solasodine of 250 mg/L. The release of solasodine did not happen in simulated gastric solution (pH of 1.2) over 12 hours. In simulated intestine solution (pH of 7.4), solasodine was gradually released in the first four hours, drastically released in the fifth hour, and gradually released again in the sixth hour until twelfth hour.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • AKTIVITAS ANTIOKSIDAN BIJI KAKAO (Theobroma cacao L.) DALAM MENURUNKAN
           KADAR 8-HIDROKSI-2’-DEOKSIGUANOSIN DALAM URIN TIKUS SETELAH TERPAPAR
           ETANOL

    • Authors: Mahardika Aprilia Iflahah, Ni Made Puspawati, Ni Made Suaniti
      Pages: 113 - 119
      Abstract: ABSTAK: Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan biji kakao pada fraksi yang memiliki aktivitas antioksidan paling tinggi secara in vitro dalam menurunkan kadar 8-OHdG dalam urin tikus yang terpapar etanol. Uji aktivitas antioksidan dilakukan dengan metode DPPH dan pengukuran kadar 8-OHdG dalam urin tikus dilakukan dengan metode ELISA. Biji kakao dimaserasi dengan pelarut etanol dan selanjutnya dipartisi dengan pelarut n-heksana, etil asetat, dan n-butanol. Uji aktivitas antioksidan secara in vitro dengan metode DPPH menunjukkan bahwa fraksi n-butanol memiliki aktivitas antioksidan paling tinggi dengan nilai IC50 170 ppm. Berdasarkan analisis statistik, data kadar 8-OHdG pada kelompok pemberian fraksi n-butanol berbeda nyata (p<0,05). Sehingga, pemberian fraksi n-butanol berpengaruh terhadap penurunan kadar 8-OHdG dalam urin tikus yang terpapar etanol dibandingkan dengan kelompok kontrol negatif dengan efektivitas penurunan kadar 8-OHdG untuk dosis 50 mg/kg BB; dosis 100 mg/kg BB; dan 200 mg/kg BB berturut-turut adalah 21,20%, 31,34%, dan 35,28%.     ABSTRACT: This study aimed to determine antioxidant activity of cocoa beans in fraction that has the highest antioxidant activity in lowering 8-OHdG level in urine after exposuring to ethanol. Antioxidant activity test was conducted using DPPH and measurement 8-OHdG level in urine was carried out by ELISA. Cocoa beans was macerated with ethanol and partitioned with n-hexane, ethyl acetate, and n-butanol. Antioxidant activity test by DPPH method showed that n-butanol fraction has the highest antioxidant activity with IC50 value of 170 ppm. Based on statistical analysis, n-butanol fraction was significantly reduced the urinary level of 8-OHdG (p<0,05) in rats after exposuring to ethanol compared to negative control group. The level effectiveness of n-butanol fraction in decreasing the level of urinary 8-OHdG was 21,20% at dose 50 mg/kg of  BW; 31,34% at dose 100 mg/kg of BW; and 35,28% at dose 200 mg/kg of BW.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • POTENSI MINYAK ATSIRI RIMPANG JERINGAU (Acorus calamus Linn) SEBAGAI
           PENGHAMBAT PERTUMBUHAN Fusarium solani, JAMUR PATOGEN PENYEBAB BUSUK
           BATANG PADA BUAH NAGA

    • Authors: Wiwik Susanah Rita, Ida Ayu Raka Astiti Asih, Ni Made Yuliari
      Pages: 120 - 128
      Abstract: ABSTRAK: Isolasi dan uji aktivitas minyak atsiri rimpang jeringau (Acorus calamus Linn) sebagai penghambat pertumbuhan jamur patogen Fusarium solani telah dilakukan. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur terhadap Fusarium solani dan kandungan utama dari minyak atsiri rimpang jeringau. Ekstraksi minyak atsiri dilakukan dengan metode destilasi uap, sedangkan uji aktivitas antijamur dilakukan dengan metode sumur difusi, dan identifikasi dilakukan dengan gas kromatografi – spektrometri massa (GC-MS). Ekstraksi 10 kg rimpang jeringau menghasilkan 13,39 gram minyak dengan hasil rendemen sebesar 0,1339%. Minyak atsiri memiliki warna kuning dan bau yang sangat tajam. Hasil uji aktivitas antijamur Fusarium solani terhadap minyak atsiri konsentrasi 10% menunjukkan aktivitas kuat dengan daya hambat sebesar 10,00 mm. Nilai Minimum Inhibitory Consentration (MIC) sebesar 2,0 % (v/v) dengan diameter hambat sebesar 5,50 mm. Hasil uji daya hambat pertumbuhan koloni, spora, dan biomassa jamur meningkat dengan kenaikan konsentrasi minyak atsiri. Analisis dengan gas kromatografi – spektrometri massa (GC-MS) menunjukkan bahwa komponen terbesar minyak atsiri jeringau adalah senyawa asaron.     ABSTRACT: Isolation and Activity test of Jeringau rhizome’s essential oil (Acorus Calamus Linn) to inhibit the growth of fungal pathogen, Fusarium solani has been performed. The aim of this research are to determine the antifungal activity and essential oil’s components of Jeringau rhizome. The extraction process was performed by steam distillation method, antifungal activity was analysed by well diffusion method, and the Gas Chromatography-Mass Spectrometry (GC-MS) was used to determine the essential oil components. The yield of essential oil was 0.1339% and has yellow colour with pungent smell. At concentration of 10.0%, the essential oil extract gave the strong activity to inhibit the Fusarium solani, with 10 mm in diameter. Minimum Inhibitory Concentration (MIC) was 2.0% that gave inhibition’s zone of 5.50 mm. Inhibition of colony, spore, and biomass of fungi increase with concentration. Analysis using GC-MS indicated the main essential compound is asarone.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • UJI EFEKTIFITAS EKSTRAK DAUN TREMBESI (Samanea saman (jacq.) Merr) SEBAGAI
           ANTIBAKTERI Escherichia coli Dan Staphylococcus aureus

    • Authors: Ni Ketut Sinarsih, Wiwik Susanah Rita, Ni Made Puspawati
      Pages: 129 - 136
      Abstract: ABSTRAK: Penelitian ini dilakukan untuk menentukan efektivitas ekstrak daun trembesi dalam menghambat pertumbuhan bakteri E. coli dan S. aureus, yang meliputi penentuan pelarut terbaik, toksisitas akut terhadap mencit, konsentrasi optimum, serta senyawa yang berperan sebagai antibakteri. Hasil penelitian menunjukkan bahwa ekstrak etanol daun trembesi memberikan efek penghambatan yang lebih baik dibandingkan ekstrak air, yaitu sebesar 11 mm terhadap S. aureus dan sebesar 8,67 mm terhadap E. coli pada konsentrasi 4%. Uji toksisitas akut ekstrak etanol pada mencit memberikan hasil LD50 16000 mg/kg BB/hari, yang masuk dalam kategori tidak toksik. Konsentrasi optimum ekstrak etanol dalam menghambat pertumbuhan bakteri dilakukan secara in vitro pada media Mueller Hinton dan dianalisis dengan Duncan Multiple Range Test dengan hasil 8,3% terhadap S. aureus dan 9% terhadap E. coli. Pada konsentrasi tersebut, aktivitas antibakteri ekstrak etanol daun trembesi dapat dikategorikan sedang terhadap E. coli dan kuat terhadap S. aureus. Uji fitokimia menunjukkan bahwa senyawa-senyawa yang berperan dalam aktivitasnya sebagai antibakteri yaitu alkaloid, steroid, fenol, flavonoid, dan saponin.   ABSTRACT: This research has been conducted to determine the effect of Samanea saman (Jacq.) Merr leaf extract in inhibiting the growth of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) bacteria. The research includes the determination of the best solvent, the acute toxicity testing in mice, the optimum concentrations, and the identification of compounds that influenced the antibacterial activity. The results showed that the ethanol extract of S. saman leaves at concentration of 4% gave a better inhibitory effect than the water extract that was 11.00 mm against S. aureus and 8.67 mm against E. coli. The acute toxicity test of ethanol extract in mice gave LD50 of 16000 mg/kg BW/day indicating that the extract was safe for consumption in the test animal. The optimum concentration of ethanol extract in inhibiting the growth of bacteria on Mueller Hinton media was analyzed by Duncan Multiple Range Test and it was found to be 8.3% against S. aureus and 9% against E. coli. Phytochemical testing result indicated the presence of alkaloids, steroids, phenols, flavonoids, and saponins which may influence the antibacterial activities of  ethanol extract of S. saman leaves.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • PENGARUH BIOFILM TERHADAP EFEKTIVITAS PENURUNAN BOD, COD, TSS, MINYAK DAN
           LEMAK DARI LIMBAH PENGOLAHAN IKAN MENGGUNAKAN TRICKLING FILTER

    • Authors: Arik Agustina, Iryanti Eka Suprihatin, James Sibarani
      Pages: 137 - 145
      Abstract: ABSTRAK : Penelitian mengenai proses pengolahan limbah dari pabrik pengolahan ikan menggunakan trickling filter bertujuan untuk mengetahui pengaruh sumber mikroorganisme terhadap pembentukan biofilm serta pengaruh biofilm dan variasi sirkulasi terhadap efektivitas penurunan Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Total Suspended Solid (TSS), minyak dan lemak dari limbah pengolahan ikan. Penelitian ini diawali dengan pembuatan biofilm dari pecahan genting sebagai media menggunakan air limbah pengolahan ikan dan air sungai sebagai sumber mikroorganisme. Setelah biofilm terbentuk, air limbah dipercikkan ke dalam bak yang berisi biofilm tersebut sebanyak 4 kali sirkulasi. BOD, COD, TSS, minyak dan lemak diukur pada masing-masing sirkulasi. Data dianalisis dengan menggunakan ANOVA dua arah untuk mengetahui pengaruh sumber mirkroorganisme dan variasi sirkulasi pada efektivitas sistem dalam menurunkan parameter pencemar. Sumber mikroorganisme dari limbah pengolahan ikan lebih efektif dibandingkan air sungai. Analisis menujukkan bahwa sirkulasi 4 lebih Efektif dalam menurunkan BOD, COD, TSS, minyak dan lemak dengan persentase secara berurutan adalah 87,50%; 59,57%; 91,85%; dan 88,56%.   ABSTRACT : The research on waste treatment process from fish processing plant by using trickling filter aims to determine the  influence of source of microorganisms on biofilm formation, and the effect of biofilm and the number of circulation on the decrease of Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Total Suspended Solid (TSS), oil and grease. This study started with the formation of biofilm on roof tiles as the media, using fish processing waste and river water as the sources of microbes. The liquid waste was then trickled through the biofilm and circulated for four times. Samples were collected at each circulation and were analysed for their BOD, COD, TSS, Oil and fat concentrations. Data were analysed using two way ANOVA to determine the effect of microbe sources and circulation numbers on the effectivity of the system in decreasing the pollutant parameters. It was evident that biofilm formed by the fish processing waste was more effective than that by river water. The analysis also suggested that 4 circulations lower the BOD, COD, TSS, oil and grease most effectively, with the percentages of 87,50%; 59,57%; 91,85%, and 88,56% respectively.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • POTENSI FLAVONOID EKSTRAK BIJI MAHONI (Swietenia mahagoni Jacq) UNTUK
           MENURUNKAN KONSENTRASI 8-OHdG PADA URIN TIKUS WISTAR JANTAN YANG TERPAPAR
           ETANOL

    • Authors: Agung Ari Chandra Wibawa, I Made Dira Swantara, Manuntun Manurung
      Pages: 146 - 152
      Abstract: ABSTRAK : Penelitian ini bertujuan untuk menentukan fraksi aktif senyawa flavonoid  biji mahoni sebagai antioksidan untuk menurunkan konsentrasi 8-OHdG dalam urin tikus yang terpapar etanol. Uji kadar total flavonoid pada fraksi dilakukan dengan metode spektrofotometri UV-Vis yang menunjukan fraksi n-butanol mengandung flavonoid terbanyak yaitu sebesar 41,734 mg/L. Pengukuran konsentrasi 8-OHdG dilakukan dengan ELISA pada panjang gelombang 450 nm. Hasil analisis dengan ELISA, dosis 50, 100, 150, dan 200 mg/kg selama 21 hari bb terbukti dapat menurunkan konsentrasi 8-OHdG pada urin tikus yang terpapar etanol selama 30 hari. Konsentrasi 8-OHdG pada perlakuan fraksi n-butanol dosis 50, 100, 150, dan 200 mg/kg bb, secara berturut-turut dapat diprediksi membutuhkan waktu selama 64, 66, 54, dan 32 hari agar konsentrasi 8-OHdG menjadi 0,3318 ng/mL.   ABSTRACT : This study aims to determine the active fraction flavonoid compounds in mahoni seeds as the antioxidant in decreasing urinary concentration of 8-OHdG in rats after being exposed to ethanol. Total flavonoid test was conducted using spectrophotometry UV-Vis method showing that n-buthanol fraction has the highest flavonoid level of 41,73 mg/L. The measurement of urinary 8-OHdG concentration has been carried out by ELISA on wavelength of 450 nm. The results showed that the concentration of 8-OHdG with dose of 50, 100, 150, and 200 mg/kg of body weight decreased during 21 days in male rats after being exposed to ethanol. The 8-OHdG concentration after treatment with  n-buthanol fractions with doses of 50, 100, 150, and 200 mg/kg of body weight was predicted to be 0,3318 ng/mL after 64, 66, 54, 31 days respectively.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • SINTESIS KOMPOSIT ZnO-BENTONIT dan PENGGUNAANNYA DALAM PROSES DEGRADASI
           METHYL ORANGE

    • Authors: Olivia Carolyn Sitepu, Oka Ratnayani, Iryanti Eka Suprihatin
      Pages: 153 - 160
      Abstract: ABSTRAK: Penelitian ini bertujuan untuk menentukan kondisi optimum proses degradasi methyl orange dengan menggunakan komposit ZnO-bentonit. Komposit ZnO-bentonit telah disintesis melalui proses sonikasi menggunakan ultrasonic batch selama 3 jam. Komposit tersebut dikarakterisasi menggunakan FTIR, XRD dan SEM, dan kemudian diaplikasikan sebagai fotokatalis dalam proses degradasi methyl orange menggunakan iradiasi sinar UV. Kondisi optimumnya didapat pada pH 5, konsentrasi komposit ZnO-bentonit sebesar 10 g/L dan waktu iradiasi selama 15 menit. Pada kondisi optimum tersebut, dihasilkan degradasi methyl orange menggunakan komposit ZnO-bentonit sebesar 56,71±0,65%.
      ABSTRACT: This research aims to determine the optimum conditions of degradation of methyl orange by using ZnO-Bentonite composite. ZnO-bentonite composite had been synthesized through sonicationby using ultrasonic batch for 3 hours. The particles were characterized by FTIR, XRD and SEM, and then applied as photocatalyst for degradation of methyl orange with UV irradiation. The optimum conditions were obtained at pH 5, composite concentration of 10 g/L, and irradiation time of 15 minutes. The result showed that at the optimum conditions, the percentage of degradation of methyl orange by using ZnO-bentonit composite was 56,71±0,65%.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • DETEKSI MUTASI KODON 510 dan 511 DAERAH RRDR GEN rpoB PADA ISOLAT KLINIK
           Mycobacterium tuberculosis MULTIDRUG RESISTANT DI BALI DENGAN
           PCR-RESTRICTION FRAGMENT LENGHT POLYMORPHISM

    • Authors: Made Rai Dwitya Wiradiputra, Sagung Chandra Yowani, I Nengah Wirajana
      Pages: 161 - 167
      Abstract: ABSTRAK: Tujuan penelitian ini adalah untuk melakukan deteksi mutasi daerah RRDR gen rpoB Mycobacterium tuberculosis khususnya pada kodon 510 dan 511 dari isolat klinis Multidrug Resistant Tuberculosis (MDR-TB) di Bali dengan metode Polymerase Chain Reaction – Restriction Fragment Length Polymorphism (PCR-RFLP). Isolat M. tuberculosis H37Rv digunakan sebagai kontrol bakteri yang tidak mengalami mutasi dan empat isolat klinis MDR-TB digunakan sebagai sampel pada penelitian ini. Proses PCR-RFLP meliputi dua tahap, yaitu amplifikasi (PCR) dan digesti. Produk PCR hasil amplifikasi didigesti dengan enzim PvuII (New England Biolabs) melalui proses inkubasi pada suhu 37oC selama 3 jam diikuti dengan inaktivasi ice shock pada suhu -20oC selama 5 menit. Hasil penelitian ini menunjukan bahwa enzim restriksi PvuII dapat mendeteksi mutasi kodon 510 dan 511 daerah RRDR gen rpoB M. tuberculosis dengan teknik PCR-RFLP. Pada isolat 134 diketahui terdapat mutasi pada kodon 510 dan/atau 511 sedangkan pada isolat P10, P11, dan P16 tidak ditemukan adanya mutasi pada kodon 510 dan 511. Berdasarkan hasil penelitian sebelumnya, diketahui pula bahwa mutasi yang terjadi pada isolat 134 adalah mutasi kodon 510 (CAG'CTG).   ABSTRACT: The objective of this study is to detect mutation in the region of RRDR of rpoB gene Mycobacterium tuberculosis particularly at codon 510 and 511 from MDR-TB clinical isolates in Bali using Polymerase Chain Reaction – Restriction Fragment Length Polymorphism (PCR-RFLP) method. Isolate of M. tuberculosis H37Rv was used as control of non-mutated bacteria, and four MDR-TB clinical isolates were used for sample in this study. PCR-RFLP was conducted in two steps which were amplification (PCR) and digestion. PCR products were digested using PvuII restriction enzyme (New England Biolabs) through incubation at 37oC for 3 hours followed by ice shock inactivation at -20oC for 5 minutes. The result of this study showed that PvuII restriction enzyme could detect mutation of codon 510 and 511 in the region of RRDR of rpoB gene M. tuberculosis using PCR-RFLP. In isolate 134, mutation at codon 510 and/or 511 was found while there were no mutation of codon 510 and 511 detected in isolate P10, P11, and P16. Based on previous research, it was found that the mutation occurred in isolate 134 was at codon 510 (CAG'CTG).
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
  • PEMBUATAN DAN KARAKTERISASI ARANG DARI BATANG TANAMAN GUMITIR (Tagetes
           erecta) PADA BERBAGAI SUHU DAN WAKTU PIROLISIS

    • Authors: I Made Siaka, Ni Putu Diana Febriyanti, Emmy Sahara, I Made Sutha Negara
      Pages: 168 - 177
      Abstract: ABSTRAK: Telah dilakukan penelitian tentang pembuatan dan karakterisasi arang dari batang tanaman gumitir (Tagetes erecta) pada berbagai suhu dan waktu pirolisis. Penelitian ini dilakukan untuk memperoleh suhu dan waktu yang optimum dalam pembuatan arang serta mengetahui karakteristik arang yang dihasilkan pada suhu dan waktu optimumnya. Karakteristik arang mengacu pada SNI 06–3730-1995 dengan melakukan analisis terhadap kadar air, abu, volatile, dan karbon serta daya serapnya terhadap odine dan metilen biru. Suhu optimum pirolisis pembuatan arang adalah 300oC dengan karakteristik terbaik berupa rendemen, kadar air, volatile, abu, dan karbon berturut-turut sebesar 40,27 ±; 4,00 ± 0,00; 6,58 ± 0,07; 4,34 ± 1,22; dan 85,06%, serta daya serapnya terhadap iodin dan metilen biru sebesar 631,0935 ± 0,00 dan 131,34 ± 1,7 mg/g arang. Waktu pirolisis optimum adalah 90 menit dengan karakterisitik paling baik, yakni rendemen, kadar air, volatile, abu, dan karbon berturut-turut sebesar 42,30 ± 8,7; 2,00 ± 0,00; 2,87 ± 0,07; 9,68 ± 1,17; dan 85,44% serta daya serapnya terhadap iodin dan metilen biru sebesar 647,4642 ± 0,00 dan 136,20 ± 1,28 mg/g arang. Arang yang dihasilkan dari pirolisis pada suhu dan waktu optimum memiliki karakteristik yang sesuai dengan SNI 06-3730-1995 memiliki gugus fungsi O-H dan berupa karbon alifatik.  ABSTRACT: This paper discusses the manufacture and characterization of carbon made from the stems of marigold (Tagetes erecta) at various temperatures and times of pyrolysis. This research aimed to obtain the optimum temperature and time of pyrolising in producing carbon, as well asto recognize the characteristics of the carbon produced. Characteristics of the carbon quality followed the Indonesian National Standard (SNI) 06-3730-1995 by analyzing the contents of water, volatile substances, ash, and carbon, as well as, the ability of the carbon in absorption capacities of iodine and methylene blue. The optimum pyrolysis temperature in producing carbon was 300oC with the best characteristics including result rendement, contents of water, volatile substances, ash, and carbon were 40,27 ± ; 4,00 ± 0,00; 6,58 ± 0,07; 4,34 ± 1,22, and 85,06%b/b respectively, as well as, the absorption capacities of iodine and methylene blue were 631,0935 ± 0,00 mg/g and 131,34 ± 1,7 mg/g respectively. The optimum time of pyrolysis in producing carbon was 90 minutes with the best characteristics including result rendement, contents of water, volatile substances, ash, and carbon were 42,30 ± 8,7; 2,00 ± 0,00; 2,87 ± 0,07; 9,68 ± 1,17; and 85,44% b/brespectively, as well as, the absorption capacities of iodine and methylene blue were 647,4642 ± 0,00and the 136,20 ± 1,28 mg/g respectively. The carbon produced from the optimum of pyrolysis temperature and time had characteristic in accordance with the SNI 06-3730-1995, it contained O-H functional group and it is in aliphatic structure.
      PubDate: 2017-03-02
      Issue No: Vol. 4, No. 2 (2017)
       
 
 
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