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Bioorganic & Medicinal Chemistry Letters
Journal Prestige (SJR): 0.81

Citation Impact (citeScore): 3
Number of Followers: 61

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0960-894X - ISSN (Online) 1464-3405
Published by Elsevier

[2974 journals]

Di-Fluoro Azepane HBV Capsid Assembly Modulators
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  Abstract: Publication date: Available online 27 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Lindsey G. DeRatt, Bart Stoops, Paul Shaffer, Angela M. Lam, Christine Espiritu, Robert Vogel, Vincent Lau, Osvaldo A. Flores, Scott D. Kuduk
Design, synthesis and biological evaluation of novel indole-3-carboxylic
acid derivatives with antihypertensive activity
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  Abstract: Publication date: 15 June 2023Source: Bioorganic & Medicinal Chemistry Letters, Volume 90Author(s): Andrey V. Danilenko, Alexander N. Volov, Nikolai A. Volov, Yana B. Platonova, Serguei V. Savilov
Synthesis, Modeling, and Biological Evaluation of Anti-Tubulin
Indole-Substituted Furanones
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  Abstract: Publication date: Available online 24 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Brianna Hurysz, Blake A. Evans, Reuben N. Laryea, Brooke E. Boyer, Taylor E. Coburn, Molly S. Dexter, Marissa A. Edwards, Grace V. Faulkner, Rebecca L. Huss, Megan M. Lafferty, Maegan Manning, Matthew McNulty, Sophia J. Melvin, Christina M. Mitrow, Roslyn R. Patel, Kelsey Pierce, Jack Russo, Allie M. Seminer, Kaitlynn A. Sockett, Nathan R. Webster
Graphical abstract TOC
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  Abstract: Publication date: 1 June 2023Source: Bioorganic & Medicinal Chemistry Letters, Volume 89Author(s):
Graphical abstract TOC
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  Abstract: Publication date: 1 June 2023Source: Bioorganic & Medicinal Chemistry Letters, Volume 89Author(s):
Contents continued
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  Abstract: Publication date: 1 June 2023Source: Bioorganic & Medicinal Chemistry Letters, Volume 89Author(s):
[¹⁸F]ONO-8430506: A novel radioligand for PET imaging of
autotaxin (ATX)
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  Abstract: Publication date: Available online 20 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Edris Ebrahimi, Melinda Wuest, Jatinder Kaur, Atul Bhardwaj, Narendar Reddy Gade, Frank Wuest
Green Synthesis of Nitroaryl Thioureas: Towards an Improved Preparation of
Guanidinium DNA Binders
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  Abstract: Publication date: Available online 20 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Marco Minneci, Matas Misevicius, Isabel Rozas
Generation and structure-activity relationships of novel
imidazo-thienopyridine based TLR7 agonists: application as payloads for
immunostimulatory antibody drug-conjugates
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  Abstract: Publication date: Available online 20 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Michael G. Brant, Graham A.E. Garnett, Joy Guedia, Manuel Lasalle, Samuel Lawn, Mark E. Petersen, Renee Duan, Jose Mendez-Campos, Truman Hirkala-Schaefer, Geoffrey C. Winters, Stuart D. Barnscher
Design, Synthesis and Characterizations of Prodrugs of Brexanolone
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  Abstract: Publication date: Available online 20 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Lianhong Xu, Ji Ma, Leifeng Shi, Fuying Li
Design and synthesis of 4-acetoxypentanamide derivatives of spliceostatin
A and their biological evaluation towards prostate cancer treatment
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  Abstract: Publication date: Available online 18 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Satoru Hirabayashi, Yuko Tsuyuguchi, Yue Li, Noriko Ohta, Yusuke Yoshikawa, Bangzhong Lin, Megumi Fumimoto, Kazuto Nunomura, Takeyuki Suzuki, Junichi Haruta, Keisuke Nimura, Mitsuhiro Arisawa
The rational design of novel 5-amino-2-oxindole derivatives with
antiglaucomic activity
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  Abstract: Publication date: Available online 18 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Roman O. Eremeev, Olga V. Beznos, Alexander M. Efremov, Natalia B. Chesnokova, Natalia A. Lozinskaya
Identification of new Hit to lead magmas inhibitors as potential
therapeutics for Glioblastoma
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  Abstract: Publication date: Available online 16 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Bhaskar C. Das, Javier J. Lepe, Mohammed Adil Shareef, Naomi Lomeli, Sasmita Das, Daniela A. Bota
In Vivo Tracking of Plasmid DNA/mRNA: a Novel Labelling Precursor for 89Zr
Positron Emission Tomography
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  Abstract: Publication date: Available online 15 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Naohiro Aoyama, Sadaaki Kimura, Toshiyuki Matsui, Takashi Nozawa
Structure-activity relationship of BMS906024 derivatives for
Cryptosporidium parvum growth inhibition
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  Abstract: Publication date: Available online 15 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Seungheon Lee, Melissa S. Love, Ramkumar Modukuri, Arnab K. Chatterjee, Lauren Huerta, Ann P. Lawson, Case W. McNamara, Jan R. Mead, Lizbeth Hedstrom, Gregory D. Cuny
Improved Synthesis and Anticancer Activity of a Potent Neuronal Nitric
Oxide Synthase Inhibitor
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  Abstract: Publication date: Available online 15 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Dhananjayan Vasu, Cory T. Reidl, Eric Wang, Sun Yang, Richard B. Silverman
Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in
the brain
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  Abstract: Publication date: Available online 13 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Aya Ogata, Takashi Yamada, Saori Hattori, Hiroshi Ikenuma, Junichiro Abe, Masanori Ichise, Masaaki Suzuki, Kengo Ito, Takashi Kato, Kazuma Amaike, Tsuyoshi Hirota, Kenichiro Itami, Yasuyuki Kimura
Evaluating the druggability of TrmD, a potential antibacterial target,
through design and microbiological profiling of a series of potent TrmD
inhibitors
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  Abstract: Publication date: Available online 13 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Andrew J. Wilkinson, Nicola Ooi, Jonathan Finlayson, Victoria E. Lee, David Lyth, Kathryn S. Maskew, Rebecca Newman, David Orr, Keith Ansell, Kristian Birchall, Peter Canning, Peter Coombs, Lucia Fusani, Ed McIver, João Pisco, Philip M. Ireland, Christopher Jenkins, Isobel H. Norville, Stephanie J. Southern, Richard Cowan
The lipidation and glycosylation enabling bioactivity enhancement and
structural change of antibacterial peptide G3
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  Abstract: Publication date: Available online 13 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Ruipin Cao, Li Li, Zuxian Xu, Jiaxin Li, Danli Wu, Yinglu Wang, Hu Zhu
Identification of (-)-Epigallocateshin Gallate Derivatives promoting
innate immune activation via 2′ 3′-cyclic GMP-AMP-stimulator of
interferon genes pathway
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  Abstract: Publication date: Available online 13 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Hyelim Lee, Jeong Hyun Jeong, Taegum Lee, Youhoon Chong, Hyunah Choo, Sanghee Lee
Design, syntheses and biological evaluation of natural product aiphanol
derivatives and analogues: discovery of potent anticancer agents
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  Abstract: Publication date: Available online 12 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Licheng Yao, Wenqing Cai, Shanmei Chen, Aidan Wang, Xin Wang, Chuanke Zhao, Chengchao Shou, Yanxing Jia
Discovery of Novel Bicyclic[3.3.0]proline Peptidyl α-Ketoamides as Potent
3CL-Protease Inhibitors for SARS-CoV-2
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  Abstract: Publication date: Available online 12 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Xiaoxin Chen, Peng Li, Jianzhou Huang, Yaxun Yang, Haoyu Zhang, Zheng Wang, Zhenzhen Zhu, Jingjing Wang, Jianchen Zhang, Kevin Chen, Haiying He, Chaofeng Long, Shuhui Chen
SolS-catalyzed sulfoxidation of labionin to solabionin drives
antibacterial activity of solabiomycins
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  Abstract: Publication date: 1 June 2023Source: Bioorganic & Medicinal Chemistry Letters, Volume 89Author(s): Shinta Ijichi, Shotaro Hoshino, Shumpei Asamizu, Hiroyasu Onaka
Design, Synthesis and Biological Evaluation of Novel Indole-piperazine
Derivatives as Antibacterial Agents
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  Abstract: Publication date: Available online 6 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Ting Liu, Xiaofang Yao, Rongrong Zhang, Tianling Wu, Zhigang Liu, Ding Li, Qingjian Dong
Synthesis of 6-alkoxy and 6-hydroxy-alkyl amine derivatives of braylin as
vasorelaxing agents
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  Abstract: Publication date: Available online 4 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Kripa Shankar Nainawat, Sarita Singh, Karishma Agarwal, Hina Iqbal, Poonam Rani, Divya Bhatt, Sana Khan, Debabrata Chanda, Dnyaneshwar Umrao Bawankule, Sudeep Tandon, Feroz Khan, Anil Kumar Gupta, Atul Gupta
Discovery of arylsulfonamides as a novel class of allosteric integrase
inhibitors with antiviral activity
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  Abstract: Publication date: Available online 3 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Cheng Wang, Gregory C. Adam, Christine Burlein, Steven Carroll, William Dankulich, Tracy Diamond, Jay Grobler, Jeffrey Heath, Adam Johnson, Daniel Klein, Daniel Krosky, Kartik Narayan, Yangsi Ou, John Sanders, Sujata Sharma, Min Xu, Antonella Converso
Development of a fluorescence screening assay for binding partners of the
iron-sulfur mitochondrial protein mitoNEET
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  Abstract: Publication date: Available online 1 May 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Ebenezer Newton, Sarah A. Starcovic, Michael Menze, Mary E. Konkle, Timothy E. Long, Lori A. Hazlehurst, Jason D. Huber, Aaron R. Robart, Werner J. Geldenhuys
Discovery of imidazo[1,2-b]pyridazine macrocyclic derivatives as novel ALK
inhibitors capable of combating multiple resistant mutants
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  Abstract: Publication date: Available online 29 April 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Xiaofei Xiao, Yunsheng Xu, Xihua Yu, Yinbo Chen, Weiwei Zhao, Zhendong Xie, Xueyan Zhu, Hongjiang Xu, Yulei Yang, Peng Zhang
Development of actein derivatives as potent anti-triple negative breast
cancer agents
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  Abstract: Publication date: Available online 28 April 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Honglin Zhang, Yiyan Chen, Songwen Huang, Wen-Wen Xiao, Ming-Hua Qiu, Li-Dong Shao, Chuan-Huizi Chen, Dashan Li
Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved
potency and efficacy as non-electrophilic antioxidant response element
(ARE) activators
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  Abstract: Publication date: Available online 26 April 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Jeyun Jo, Jisu Kim, Lara Ibrahim, Manoj Kumar, Jonathan Iaconelli, Cong So Tran, Hyung Ryong Moon, Yunjin Jung, R. Luke Wiseman, Luke L. Lairson, Arnab K. Chatterjee, Michael J. Bollong, Hwayoung Yun
Filling a nick in NIK: extending the half-life of a NIK inhibitor through
structure-based drug design
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  Abstract: Publication date: Available online 25 April 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): James J. Crawford, Jianwen Feng, Hans D. Brightbill, Adam R. Johnson, Matthew Wright, Aleksandr Kolesnikov, Wendy Lee, Georgette M. Castanedo, Steven Do, Nicole Blaquiere, Steven T. Staben, Po-Chang Chiang, Peter W. Fan, Matt Baumgardner, Susan Wong, Robert Godemann, Alice Grabbe, Catharina Wiegel, Swathi Sujatha-Bhaskar, Sarah G. Hymowitz
Identification and structure-activity relationships for a series of N,
N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus
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  Abstract: Publication date: Available online 23 April 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Feng Cao, Ramakumar Kinthada, Terri Boehm, Napoleon D' Cunha, Inga V. Leus, Cari Orth, Helen I. Zgurskaya, John K. Walker
Prevention of the Lachnum polysaccharide and its selenium derivatives on
cisplatin-induced acute kidney injury in mice
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  Abstract: Publication date: Available online 20 February 2023Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Yaling He, Dong Liu, Changsong Zhu, Xue Chen, Hongling Ye, Ming Ye