JournalTOCs

Analyst
Journal Prestige (SJR): 1.249

Citation Impact (citeScore): 4
Number of Followers: 35

Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0003-2654 - ISSN (Online) 1364-5528
Published by RSC

[50 journals]

Cyanine dye-assembled composite upconversion nanoparticles for the sensing
and cell imaging of nitrite based on a single particle imaging method
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00594H, PaperYunchun Liu, Wanru Zhu, Xinru Wei, Lun Wang, Hongqi Chen
  In this work, a single particle imaging method based on the total internal reflection (TIR) imaging platform for the sensing and cell imaging of nitrite (NO2-) in the near-infrared region...
  The content of this RSS Feed (c) The Royal Society of Chemistry
Bypassed ion-selective electrodes – self-powered polarization for
tailoring of sensor performance
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00458E, PaperAnna Kisiel, Agata Michalska, Krzysztof Maksymiuk
  The bypass circuit with zinc wire induces spontaneous charge flow: oxidation of zinc and reduction of the solid contact of K-ISE. This effect is helpful in the improvement of analytical parameters of K-ISE.
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Picomolar level Electrochemical Detection of Hydroquinone, Catechol and
Resorcinol Simultaneously Using a MoS2 Nano-Flower Decorated Graphene
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00531J, PaperArya J. S Nair, Saisree S, K. Y. Sandhya
  Herein, a graphene-nano-molybdenum disulphide (pGr-MoS2), synthesized from pulverized graphite and using precursors of MoS2, was investigated for the electrochemical sensing of dihydroxy benzene isomers (DHBI): hydroquinone (HQ), catechol (CA), and...
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Microfluidic Flow Cytometry for Blood-Based Biomarker Analysis
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00283C, Critical Review Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuxin Zhang, Ying Zhao, Tim Cole, Jiahao Zheng, Qiaoge Bayin, Jinhong Guo, Shiyang Tang
  Flow cytometry has proven its capability for rapid and quantitative analysis of individual cells and the separation of targeted biological samples from others. The emerging microfluidics technology makes it possible...
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Solid-state Nanopore Analysis on Conformation Change of DNA Polymerase I
induced by DNA Substrate
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00567K, PaperJiye Fu, Linlin Wu, Gang Hu, Fuyao Li, Qinyu Ge, Zuhong Lu, Jing Tu
  Proteins with changeable conformation, such as polymerases, play a very important role in various life activities. Their conformational changes can be reflected in the structural size and flexibility, which may...
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Determination of intracellular ascorbic acid using tandem mass
spectrometry
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02160E, CommunicationChizumi Abe, Ohki Higuchi, Akira Matsumoto, Taiki Miyazawa
  Ascorbic acid is involved in a variety of biological events. Nevertheless, its detailed intracellular behavior remains unexplored due to lack of sensitive analytical methods. Here we report a method using...
  The content of this RSS Feed (c) The Royal Society of Chemistry
Combination of LIBS-based elemental analysis and near-infrared molecular
fingerprinting of bile juice to enhance identification of gallbladder
cancer
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00563H, PaperChanghwan Eum, Eunjin Jang, Hyang Kim, Sang-Ho Nam, Yonghoon Lee, Dongho Choi, Hoeil Chung
  Laser-induced breakdown spectroscopy (LIBS) and near-infrared (NIR) spectroscopy, enabling the measurement of raw bile directly without sample pretreatment, were cooperatively combined to enhance the discrimination of gallbladder cancer (GBC) from...
  The content of this RSS Feed (c) The Royal Society of Chemistry
Ratiometric fluorescence enzyme-linked immunosorbent assay based on carbon
dots@SiO2@CdTe quantum dots with dual functionalities for
alpha-fetoprotein
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00691J, PaperXiuhui Liang, Zhenzhen Lin, Ling Li, Dianping Tang, Jinfeng Kong
  Molecular tags such as fluorophores are increasingly being replaced with nanoparticles thanks to their superior optical properties, substantially chemical stability, and stability against photobleaching. Herein, we innovatively constructed a new...
  The content of this RSS Feed (c) The Royal Society of Chemistry
A sensitive fluorescence biosensor based on metal ion-mediated DNAzyme
activity for amplified detection of acetylcholinesterase
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00414C, PaperXu-Hua Zhao, Xiao-Chun Dai, Ya-Nan Zhou, Han-Xiao Zhang, Xiao-Hua Cui, Xiang Zhai, Bao-Feng Yu, Zhi-Ling Song
  In this paper, we developed an amplified fluorescence biosensor for acetylcholinesterase (AChE) activity detection by taking advantage of the mercury ion-mediated Mgzyme (Mg2+-dependent DNAzyme) activity.
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Fluorescence imaging of intracellular telomerase activity for tumor cell
identification by oligonucleotide-functionalized gold nanoparticles
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00525E, PaperShan Shan, Jiajia Li, Guangmei Han, Ruilong Zhang, Zhengjie Liu, Zhongping Zhang
  An oligonucleotide-functionalized gold nanoparticle probe was developed and the high-efficiency detection of telomerase activity for cellular imaging toward the identification of tumors was realized.
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Rapid separation of cannabinoid isomer sets using differential mobility
spectrometry and mass spectrometry
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  Abstract: Analyst, 2022, 147,2198-2206
  
  DOI : 10.1039/D1AN02327F, PaperNour Mashmoushi, J. Larry Campbell, Robert di Lorenzo, W. Scott Hopkins
  With legalization and decriminalization of cannabis in many parts of the world comes the need for rapid separation and quantitation of the psychoactive ingredients.
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Hyphenated structural identification of additives in transmission fluids
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  Abstract: Analyst, 2022, 147,2068-2073
  
  DOI : 10.1039/D2AN00323F, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.F. H. M. van Zelst, J. Romanuka, A. P. M. Kentgens
  A novel hyphenated analytical method to unravel complex mixtures, SFC-1H NMR/MS, is introduced. It is applied for the structural analysis of additives in transmission fluids which can be used to prolong the lifetime of lubricants.
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Sulfur atom modification on thymine improves the specificity and
sensitivity of DNA polymerization and detection
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  Abstract: Analyst, 2022, 147,2164-2169
  
  DOI : 10.1039/D1AN02017J, PaperYang Li, Wen Sun, Danyan Luo, Zhaoyi Yang, Wei He, Zhen Huang
  The incorporation of STTP can significantly reduce the non-specific amplification products in DNA polymerase reaction.
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Ultrasensitive multiwall carbon nanotube-mesoporous MCM-41 hybrid-based
platform for the electrochemical detection of ascorbic acid
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  Abstract: Analyst, 2022, 147,2130-2140
  
  DOI : 10.1039/D2AN00473A, PaperVirginia M. Vaschetti, Benjamín N. Viada, Alejandro Tamborelli, Griselda A. Eimer, Gustavo A. Rivas, Pablo R. Dalmasso
  An ultrasensitive multiwall carbon nanotube-MCM-41 hybrid-based ascorbic acid sensor for electro-detection in real samples is proposed. The MWCNT–MCM-41 hybrid preparation via dispersion was optimized through an experimental design based on CCD/RSM.
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A genosensor for detecting single-point mutations in dendron chips after
blocked recombinase polymerase amplification
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  Abstract: Analyst, 2022, 147,2180-2188
  
  DOI : 10.1039/D2AN00160H, PaperSara Martorell, Ángel Maquieira, Luis A. Tortajada-Genaro
  Dendron–probe conjugates were effectively immobilized on chip surfaces, improving assay sensitivity and simplifying coupling reactions. Combined with an isothermal amplification, the array method accurately detects single-base changes.
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Diagnostic value of serum sphingolipids in patients with colorectal cancer
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  Abstract: Analyst, 2022, 147,2189-2197
  
  DOI : 10.1039/D1AN02239C, PaperZiyue Pan, Zuojian Hu, Li Guan, Lei Zhang, Xia Gao, Lujie Yang, Tianqi Gong, Yanling Hu, Yanping Zhao, Hongxiu Yu
  We compared serum sphingolipids in healthy individuals, and polyp and colorectal cancer patients, and found that serum sphingolipid profiles shift during the development of cancer.
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Enhancing scanning electrochemical microscopy's potential to probe dynamic
co-culture systems via hyperspectral assisted-imaging
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00319H, PaperSondrica Goines, Mingchu Deng, Matthew W. Glasscott, Justin W. C. Leung, Jeffrey E. Dick
  Overcoming challenges associated with biological imaging by correlating hyperspectral imaging and scanning electrochemical microscopy; this powerful combination provides unambiguous determination of cell boundaries for studying cellular dynamics.
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An ultrasensitive electrochemical sensing platform based on silver
nanoparticle-anchored 3D reduced graphene oxide for rifampicin detection
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  Abstract: Analyst, 2022, 147,2156-2163
  
  DOI : 10.1039/D2AN00452F, PaperQing Zhang, Shangshang Ma, Xin Zhuo, Cong Wang, Hongyan Wang, Yuying Xing, Qingyuan Xue, Keying Zhang
  An accurate and reliable electrochemical sensor based on Ag NPs/3D rGO composites for ultrasensitive determination of rifampicin (RIF) is proposed and shows great potential application in clinical diagnosis, pharmaceuticals and food-related fields.
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A novel and portable electrochemical sensor for 5-hydroxymethylfurfural
detection using silver microdendrite electrodeposited paper-based
electrode
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  Abstract: Analyst, 2022, 147,2170-2179
  
  DOI : 10.1039/D2AN00346E, PaperJantima Upan, Jamras Lerdsri, Jittrapun Soongsong, Pijika Mool-am-kha, Tharinee Sridara, Preeyaporn Reanpang, Jaroon Jakmunee
  A lab-made screen-printed carbon electrode was fabricated on poster paper and modified with silver microdendrites for the determination of 5-hydroxymethylfurfural in honey.
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A bright chemiluminescence conjugated polymer–mesoporous silica
nanoprobe for imaging of colonic tumors in vivo
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  Abstract: Analyst, 2022, 147,2060-2067
  
  DOI : 10.1039/D2AN00294A, PaperYukun Li, Beibei Zhu, Wanying Han, Wei Tang, Xinrui Duan
  A chemiluminescence (CL) conjugated polymer–mesoporous silica nanoprobe with significant improvement of CL quantum yield obtained from direct oxidation of a conjugated polymer and its application for in vivo imaging of colonic tumors.
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Effects of the interaction of gunshot residue plume and cotton
fabrics—an empirical study towards extensive assessment of close-range
shooting distance
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  Abstract: Analyst, 2022, 147,2141-2155
  
  DOI : 10.1039/D1AN02001C, PaperZuzanna Brożek-Mucha, Jolanta Wąs-Gubała
  This study is focused on the distribution of gunshot residue as well as changes in the textiles to support forensic investigations of suicides and homicides committed by means of a firearm.
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Isomeric separation of permethylated glycans by extra-long reversed-phase
liquid chromatography (RPLC)-MS/MS
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  Abstract: Analyst, 2022, 147,2048-2059
  
  DOI : 10.1039/D2AN00010E, PaperJunyao Wang, Xue Dong, Aiying Yu, Yifan Huang, Wenjing Peng, Yehia Mechref
  Separation of glycans with sialic acid linkage isomers and positional fucosylated isomers derived from model glycoproteins, human serum and cancer cell lines using LC-MS/MS with a 500 mm reversed-phase C18 column.
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Simple add-on devices to enhance the efficacy of conventional surface
immunoassays implemented on standard labware
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  Abstract: Analyst, 2022, 147,2040-2047
  
  DOI : 10.1039/D2AN00214K, PaperIago Pereiro, Anna Fomitcheva Kartchenko, Robert D. Lovchik, Govind V. Kaigala
  We propose microfluidic add-ons easily placed on standard assay labware such as microwells and slides to enhance the kinetics of immunoassays. The devices are compatible with mass production, well-established assay protocols and automated platforms.
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PharmaChk: A decade of research and development towards the first
quantitative, field-based medicine quality screening instrument
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00284A, Tutorial ReviewAndrew James Acevedo, Darash Desai, Muhammad Zaman, Gabriela Apiou-Sbirlea
  Biomedical and clinical scientists play a major role in translating observations into interventions – therapeutics, diagnostics, and medical devices including screening instruments – that improve the health of individuals and...
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A Fluorimetric Test Strip with Suppressed “Coffee Ring Effect” for
Selective Mercury Ion Analysis
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00562J, CommunicationYuchun Qiao, Yu Fang, Jizhen Shang, Xiaoting Zhao, Shuai Li, Guo-Jiang Mao, Hua Wang
  Nowadays, test strips have been widely applied but mostly limited to the qualitative or half-quantitative analysis of targets, for which one of the main reasons was the formidable “Coffee Ring...
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Ultra-bright carbon quantum dots for rapid cell staining
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00325B, PaperTongtong Zhu, Lei Cao, Zhenqiao Zhou, Hanzhou Guo, Mingfeng Ge, Wen-Fei Dong, Li Li
  A schematic illustration of the synthesis of G-CDs and cell imaging under one-photon and two-photon conditions.
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Visible microspectrophotometry coupled with machine learning to
discriminate the erythrocytic life cycle stages of P. Falciparum malaria
parasites in functional single cells
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00274D, PaperJohn Adeola Adegoke, Hannah Raper, Callum Gassner, Philip Heraud, Bayden Robert Wood
  Malaria was regarded as the most devastating infectious disease of the 21st century until the COVID-19 pandemic. Asexual blood staged parasites (ABS) play a unique role in ensuring the parasite’s...
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A controllable staining colorimetric method based on carboxylated
cellulose membranes for early-warning and semi-quantitative detection of
aflatoxins in water
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D1AN02355A, PaperHeng Zhang, Wenhui Zhong, Yang Yang, Genyan Liu, Xiaogang Luo
  A controllable staining colorimetric method was proposed for antibody-free detection of AFs by exploiting controllable electrostatic-staining of CCMs with Hg2+-capped AuNPs.
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Biophysical quantification of reorganization dynamics of human pancreatic
islets during co-culture with adipose-derived stem cells
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00222A, PaperKarina Torres-Castro, Mohammad S Azimi, Walter B Varhue, Carlos Honrado, Shayn Peirce, Nathan Swami
  Islet transplantation is a potential therapy for type 1 diabetes, but it is expensive due to limited pancreas donor numbers and the variability in islet quality. The latter is often...
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Photoelectrochemical sandwich immunoassay of CYFRA21-1 based on In2O3/WO3
type-II heterojunction and CdS quantum dots-polydopamine nanospheres
labeling
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00522K, PaperLuyao Liu, Chenglong Sun, Jialin Liu, Yun Du, Qingji Xie
  Using an In2O3/WO3 type-II heterojunction modified fluorine-doped tin oxide (FTO) electrode as the photoanode and CdS quantum dots (QDs)-polydopamine nanospheres (PDA NSs) as the secondary antibody (Ab2) labeling, the photoelectrochemistry...
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In vitro electrochemical measurement of serotonin release in the human
jejunum mucosa using a diamond microelectrode
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00487A, PaperMarion France, James J. Galligan, Greg M. Swain
  We report herein on the use of a boron-doped diamond microelectrode (DME) to record oxidation currents in vitro associated with the release of serotonin from enterochromaffin cells in the epithelium of the human intestinal mucosa.
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CLASSIFICATION OF BALLPOINT PEN INKS BASED ON SELECTIVE EXTRACTION AND
SUBSEQUENT DIGITAL COLOR AND CLUSTER ANALYSES
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00482H, PaperAndrey V Kalinichev, Anastasia V Kravchenko, Ivan P Gryazev, Arseniy A Kechin, Oleg R Karpukhin, Evgeniia M Khairullina, Ludmilla Kartsova, Anna G Golovkina, Vladimir A Kozynchenko, Maria A Peshkova, Ilya Tumkin
  Here, we propose a novel approach to the classification of blue ballpoint pen inks based on a combination of selective extraction of coloring components from a paper carrier, digital color...
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Plasmon Resonance-Inspired Discriminator Unscrambles Lipoprotein Subtypes
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00550F, PaperJianfang Cao, Mingshu Shuai, Yang Shu, Jian-Hua Wang
  The cardiovascular diseases are tightly linked to circulating lipoprotein subtypes. While the significance for their discrimination is generally underappreciated. Herein, we designed a facile approach for efficacious and precise profiling...
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A novel ratiometric fluorescent and colorimetric sensor based on
1,8–naphthalimide derivative for nanomolar Cu2+ sensing: Smartphone and
food applications
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00537A, PaperSukriye Nihan KARUK ELMAS, Fatma Nur Arslan, Duygu Aydin
  A novel 1,8–naphthalimide–based chemical sensor 3-((2-(2-butyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-6-yl)hydrazone-o)methyl)-4-hydroxy-[1,1-biphenyl]-4-carbonitrile (BUDIN) with a ratiometric fluorescence behavior as well as ''naked–eye'' response was developed for sensitive and specific determination of Cu2+ in nanomolar level. With...
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A coumarin coupled tetraphenylethylene based multi-targeted AIEgen for
cyanide ion and nitro explosive detection, and cellular imaging
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00040G, PaperViraj G Naik, Sharanabasava D Hiremath, Ankit Thakuri, Vijay Hemmadi, Malabika Biswas, Mainak Banerjee, Amrita Chatterjee
  A coumarin coupled tetraphenylethylene based AIEgen (TPE-Lac) with intense greenish-yellow emission has been synthesized and utilized for multipurpose sensing and imaging applications. TPE-Lac acts as a sensitive sensor for the...
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Point-of-care detection of sevoflurane anesthetics in exhaled breath using
a miniature TOFMS for diagnosis of postoperative agitation symptoms in
children
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00479H, PaperBing Liu, Wenxi Tang, Hang Li, Ruidong Liu, Fengshuo Dong, Yingzhe Guo, Jianjun Li, Keyong Hou
  A miniature TOFMS with MEPEI has been developed for POC diagnosis of postoperative agitation symptoms, and can analyze sevoflurane by direct sampling. The risk is high when the sevoflurane in the exhaled breath is higher than 500 ppmv.
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A novel AIE fluorescent probe for the monitor of aluminum ion in living
cells and zebrafish
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00543C, PaperYabing Gan, Guoxing Yin, Jianhua Wang, Peng Yin
  A novel fluorescent probe BTD with aggregation induced emission (AIE) characteristics for the monitor of Al3+ was rationally developed. This probe could be used to detect Al3+ in aqueous...
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Plastic-based lateral flow immunoassay device for electrochemical
detection of NT-proBNP
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00685E, PaperNikhil Raj, Richard M. Crooks
  A low-cost plastic-based lateral flow device was developed to detect NT-proBNP, a heart failure marker, using the electrochemical metalloimmunoassay technique.
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Cytidine rich hydrogel as the electrochemical signal amplification
strategy for microRNAs detection
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00667G, PaperXinying Zhang, Zhiwei Zhang, chujing Yang, Ziheng Hu, Yingying Chen, Lingyan Feng
  Signal amplification strategies increased the complexities of biosensors while improving the response signals. Herein a novel electrochemical biosensor was developed based on the DNA hydrogel for sensitive analysis using the...
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A Facile Visualized Solid-Phase Detection of Virus-Specific Nucleic Acid
Sequences through An Upconversion Activated Linear Luminescence Recovery
Process
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00382A, PaperXiaorong Liu, Chaonan He, Qi Huang, Mengmeng Yu, Zhuang Qiu, Haoxin Cheng, Yifei Yang, Xian Hao, Xiaolei Wang
  The development of portable solid-phase biosensors is of great significance for point-of-care testing (POCT). In this work, we constructed a simple visualized solid-phase biosensor based on luminescence resonance energy transfer...
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Development and critical evaluation of a novel fluorescent nanosensor
based on a molecularly imprinted polymer for the rapid detection of
procymidone in ginseng
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02186A, PaperYi Huang, Nan Guo, Chaojian Xu, Ningkang Xie, Feiya Liang, Shuo Yang, Shaowu Lv
  Effective methods are required to quantify the organochlorine pesticide procymidone due to its potentially harmful effects to human health and the environment. Here, hydrophilic hollow imprinted microspheres were prepared via...
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Highly sensitive and selective surface plasmon resonance biosensor for
detection of SARS-CoV-2 spike S1 protein
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00426G, PaperQiong Wu, Wen Wu, Fangfang Chen, Ping Ren
  The reality that the coronavirus disease 2019 (COVID-19) is still raging around the world and making a comeback with a strong posture has highlighted the need for rapid and sensitive...
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Hybridizing aggregated gold nanoparticles with hydrogel to prepare
flexible SERS chip for detecting organophosphorus pesticides
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00541G, PaperJiaxin Zhang, Xiajun Zhu, Mingming Chen, Tianwen Chen, Zhihong Liu, Jianli Huang, Fengfu Fu, Zhenyu Lin, Yongqiang Dong
  Surface enhanced Raman scattering (SERS) is an ultrasensitive analytic technique. However, the application of SERS in quantitative analysis usually suffers from poor reliability due to the limitations of current developed...
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Biorecognition Antifouling Coatings in Complex Biological Fluids: A Review
of Functionalization Aspects
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00436D, Critical ReviewIvana Víšová, Milan Houska, Hana Vaisocherová-Lísalová
  Recent progress in biointerface research have highlighted the role of antifouling functionalizable coatings in the development of advanced biosensors for point-of-care bioanalytical and biomedical applications dealing with real-world complex samples....
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Ultrasensitive luteolin electrochemical sensor based on glass carbon
electrodemodified using multi-walled carbon nanotube supported hollow
cobalt sulfide (CoSx) polyhedrons / graphene quantum dots composites
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00345G, PaperLi Zhang, Pengcheng Zhao, Chenxi Wang, Yilin Wang, Yaqi Yang, Yixi Xie, Junjie Fei
  Luteolin (LU) belongs to the group of flavonoids with rich biological activities, has been attracted much attention. Herein, a novel ultrasensitive LU electrochemical sensor was proposed based on hollow cobalt...
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Ratiometric fluorescent probe: a reliable and sensitive reporter for
CRISPR/Cas12a-based biosensing platform
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00613H, PaperQiang Liu, Mei Liu, Yan Jin, Baoxin Li
  Due to the excellent activity of trans-cleavage and target recognition, the recently discovered CRISPR/Cas12a systems provide a promise opportunity for designing fluorescence biosensing. In the reported CRISPR/Cas12a-based biosensing platform, TaqMan...
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Tandem-trapped ion mobility spectrometry/mass spectrometry (tTIMS/MS): a
promising analytical method for investigating heterogenous samples.
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00335J, Critical ReviewFanny C. Liu, Mark E. Ridgeway, Melvin A. Park, Christian Bleiholder
  Ion mobility spectrometry/mass spectrometry (IMS/MS) is widely used to study various levels of protein structure. Here, we review the current state of affairs in tandem-trapped ion mobility spectrometry/mass spectrometry (tTIMS/MS)....
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Probing Low Abundant DNA Methylation by CRISPR-Cas12a-assisted Cascade
Exponential Amplification
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00170E, PaperLiangliang Zhang, Xianxian Zhao, Xiaolin Hu, Yi Zhang, Ruining Liu, Hai Peng, Youhao Chen, Hong Zhang, Yang Luo
  Aberrant DNA methylation plays a pivotal role in tumor development and metastasis, and is regarded as a valuable non-invasive cancer biomarker. However, the sensitive and accurate quantification of DNA methylation...
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The simultaneous quantitative detection of multiple hormones based on
PS-MS: affinity capture by a single antibody
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  Abstract: Analyst, 2022, 147,1853-1858
  
  DOI : 10.1039/D2AN00029F, PaperTianhao Wu, Mingying Ma, Gongwei Sun, Sichun Zhang, Xinrong Zhang
  Here, we utilized single antibody to capture and separate multiple hormones from samples to avoid LC procedures and MS/MS detection to realize simultaneously qualitative and quantitative analysis of multiple molecules in a single run.
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A sensing system constructed by combining a structure-switchable molecular
beacon with nicking-enhanced rolling circle amplification for highly
sensitive miRNA detection
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  Abstract: Analyst, 2022, 147,1937-1943
  
  DOI : 10.1039/D1AN02218K, PaperShujuan Sun, Wenqing Wang, Xuemei Hu, Cheng Zheng, Qi Xiang, Qingguo Yang, Jing Zhang, Zhi-Fa Shen, Zai-Sheng Wu
  A novel amplification assay strategy is developed for the highly sensitive detection of miRNA-21 based on a combination of a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification.
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DNA walker-amplified signal-on electrochemical aptasensors for
prostate-specific antigen coupling with two hairpin DNA probe-based
hybridization reaction
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  Abstract: Analyst, 2022, 147,1923-1930
  
  DOI : 10.1039/D2AN00327A, PaperYuyu Zheng, Jinpeng Wang, Genwang Chen, Meie Wang, Tebin Chen, Qiaohong Ke, Yajun Huang, Fan Cai, Rongfu Huang, Chunmei Fan
  An electrochemical aptasensing platform was designed for the voltammetric detection of prostate-specific antigen without any washing and separation steps.
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Nanomaterial-assisted thread-based isotachophoresis with on-thread solute
trapping
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  Abstract: Analyst, 2022, 147,1944-1951
  
  DOI : 10.1039/D2AN00287F, PaperLiang Chen, Alireza Ghiasvand, Estrella Sanz Rodriguez, Peter C. Innis, Brett Paull
  This research describes a nanomaterial-assisted TB-ITP setup for the clean-up, preconcentration, and trapping of alkaloids in biological fluids, followed by their on-thread DESI-MS determination.
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Establishing a quantitative fluorescence assay for the rapid detection of
kynurenine in urine
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  Abstract: Analyst, 2022, 147,1931-1936
  
  DOI : 10.1039/D2AN00107A, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kamlesh Patel, Marcos Fernandez-Villamarin, Craig Ward, Janet M. Lord, Peter Tino, Paula M. Mendes
  A fluorescence-based assay for the detection of kynurenine in urine for low-cost and high-throughput analysis in clinical laboratory settings.
  The content of this RSS Feed (c) The Royal Society of Chemistry
Single-Particle Spectroelectrochemistry: Electrochemical Tuning of
Plasmonic Properties via Mercury Amalgamation in Mesoporous Silica Coated
Gold Nanorods without Structural Deformation
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00559J, CommunicationYola Yolanda Alizar, Ji Won Ha
  This paper elucidates the mercury (Hg) amalgamation induced by electrochemical reduction on gold nanorods coated with mesoporous silica shell (AuNRs@mSiO2) using single-particle spectroelectrochemistry. First, the silica shell significantly enhanced the...
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The unique physical shading pattern of Rayleigh scattering for the
generally improved detection of scattering particles
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00488G, PaperZhihui Li, Yan Meng, Hongyu Nie, Rongmeng Gu, Xiaokun Wang, Dan Xiao
  The Rayleigh scattering method is a rising analytical technique for its high sensitivity and simple operability in the detection of scattered particles. Herein, an efficient and facile physical shading method...
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Mimetic peroxidase based on gold amalgam for colorimetric sensing of trace
mercury (II) in water samples
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00560C, PaperJing Jiang, Xianwen Kan
  Development of an efficient protocol to achieve the precise monitoring of trace Hg2+ is of great significance. In this work, a colorimetric sensing platform for Hg2+ monitoring was constructed by...
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H2O2 activated independently bidirectional regulation for sensitive and
accurate electrochemiluminescence ratiometric analysis
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00601D, PaperXiang-Mei Liu, Yu-Ling Wang, Shu-Wei Ren, Juntao Cao, Yan-Ming Liu
  Potential-resolved electrochemiluminescence (ECL) ratiometric analysis have become a research hotspot in bioassays in virtue of the good accuracy, versatility and specificity. The current ECL ratiometry mainly focuses on competition for...
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Enzyme-triggered click chemistry combined with surface-enhanced Raman
spectroscopy for simple and sensitive detection of alkaline phosphatase
activity from complex biological samples
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02159A, PaperFanghao Cao, Minmin Wang, Xuan Yi, Dan Sun
  Alkaline phosphatase (ALP) is a widely used indicator in the diagnosis of various diseases. Thus, it is also urgent to develop simple and efficient methods that can meet the accurate...
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Multicolor biosensor for alkaline phosphatase activity detection based on
peroxidase activity of copper nanoclusters and etching of gold nanorods
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00517D, PaperQin Luo, Yisheng Lin, Qihong Cai, Fang Luo, Cuiying Lin, Jian Wang, Bin Qiu, Zhenyu Lin
  Alkaline phosphatase (ALP) plays a vital role in clinical diagnoses and biomedical researches. It is important to develop some convenient but sensitive methods for ALP activity detection. In this study,...
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Correction: Fast label-free recognition of NRBCs by deep-learning visual
object detection and single-cell Raman spectroscopy
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN90030K, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Teng Fang, Pengbo Yuan, Chen Gong, Yueping Jiang, Yuezhou Yu, Wenhao Shang, Chan Tian, Anpei Ye
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A multifunctional colorimetric sensor array for bacterial identification
and real-time bacterial elimination to prevent bacterial contamination
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00445C, PaperMinyang Zhao, Yong Yan, Hanqiong Guo, Yujie Zhang, Haotian Wu, Yuan Fang, Yaqing Liu
  The constructed sensor array has simple operation and successfully integrates bacterial identification and inactivation.
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Construction of Ag nanowire@Au nanoparticles nano nests with densely
stacked small gaps for actively trapping molecules to realize diversity
SERS detection
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00527A, PaperPan Li, tao xie, Meihong Ge, Siyu Chen:, guangyao huang, junxiang li, meiting gong, shirui weng, Liangbao Yang
  Highly sensitive Surface-enhanced Raman spectroscopy (SERS) sensing not only depends on the active substrate with high density of hot spots, but also depends more on whether the molecules can effectively...
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Separation, identification, and conformation of cyclic and tadpole
macromolecules via UPLC-MS/MS
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00208F, PaperJason O'Neill, Jialin Mao, Farihah Haque, Fabienne Barroso-Bujans, Scott M. Grayson, Chrys Wesdemiotis
  Macrocyclic poly(glycidyl phenyl ether) (pGPE) synthesized via zwitterionic ring opening polymerization is typically contaminated by chains with linear and tadpole architecture. Although mass spectrometry (MS) analysis can readily confirm the...
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Highly catalysis amplification of MOFNd-loaded nanogold combined with
specific aptamer SERS/RRS assay of trace glyphosate
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00549B, PaperJingjing Li, Jinling Shi, Aihui Liang, Zhiliang Jiang
  The neodymium metal-organic framework (MOFNd) was prepared by using 1H-pyrazole-3,5-dicarboxylic acid (H3pdc) and 2-pyrazinecarboxylic acid as ligand. Addition of HAuCl4 as precursor and NaBH4 as reducing agent, a new MOFNd-loaded...
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Magnet-actuated microfluidic array chip for high-throughput pretreatment,
amplification and detection of multiple pathogens
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00430E, PaperMengfan Zhou, Huiying Su, Bangfeng Wang, Chao Wan, Wei Du, Peng Chen, Xiaojun Feng, Bifeng Liu
  The outbreak of global infectious diseases has posed a significant threat to public health, entailing rapid and accurate diagnosis of pathogens promptly for the society to implement immediate control measures...
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A designer DNA tetrahedron-based molecular beacon for tumor-related
microRNA fluorescence imaging in living cells
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D2AN00418F, PaperShuainan Li, Chenguang Wang, Yi Xu, Wei Wang, Xiaoshuang Zhao, Qiuling Qian, Xianqiang Mi
  A designer nanoprobe of tetrahedral DNA framework (TDF) combined with MB (termed TDFM nanoprobe) for the efficient fluorescence imaging of tumor-related miRNA-214 in living cells.
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DNA tile self-assembly driven by antibody-mediated four-way branch
migration
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  Abstract: Analyst, 2022, Advance Article
  
  DOI : 10.1039/D1AN02273C, PaperXingdi Cui, Yuan Liu, Qiang Zhang
  The antibody-mediated four-way branch migration mechanism provides a novel idea for realizing the assembly of nanostructures, simply by attaching structures such as tiles, proteins, quantum dots, etc. to the ends of the four-way branches.
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Detection of Heterocyclic Amine(PhIP) by Fluorescently Labelled
Cucurbit[7]uril
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00495J, PaperLili Sun, Wang Zejiang, Hou Juan, Guozhen Fang, Jifeng Liu, Shuo Wang
  Heterocyclic amines (HCA) were the main mutagenic factors in cooked meat products and considered to be hazardous chemicals in the field of food safty. In this study, inspired by the...
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Recent advances in spheroid-based microfluidic models to mimic tumour
microenvironment
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00172A, MinireviewJooyoung Ro, Junyoung Kim, Yoon-Kyoung Cho
  Three-dimensional (3D) multicellular spheroid models can recapitulate the human tumour microenvironment with more accuracy than conventional cell culture models, as they include complex architectural structures and dynamic cellular interactions. Among...
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Rapid identification of human muscle disease with fibre optic Raman
spectroscopy
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN01932E, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.James Alix, Maria Plesia, Gavin Rhys Lloyd, Alexander Dudgeon, Catherine A. Kendall, Channa Hewamadduma, Marios Hadjivassiliou, Christopher McDermott, Grainne Gorman, Robert Taylor, Pamela J. Shaw, John Day
  The diagnosis of muscle disorders (“myopathies”) can be challenging and new biomarkers of disease are required to enhance clinical practice and research. Despite advances in areas such as imaging and...
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Naphthalene-Functionalized Resorcinarene as Selective, Fluorescent
Self-Quenching Sensor for Kynurenic Acid
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02224E, PaperAnna Karle, Kwaku Twum, Noorhan Sabbagh, Alise Haddad, S. Maryamdokht Taimoory, Maria Bryant, Evan R. Trivedi, John Frederick Trant, Ngong Kodiah Beyeh
  Kynurenic acid is a by-product of tryptophan metabolism in humans, with abnormal levels indicative of disease. There is a need for water-soluble receptors that selectively bind kynurenic acid, allowing for...
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Label-free and ultrasensitive electrochemical biosensor for oral cancer
overexpressed 1 gene via exonuclease III-assisted target recycling and
dual enzymes-assisted signal amplification strategy
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00367H, PaperDongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao, Shan Huang
  A label-free and ultrasensitive electrochemical biosensor for oral cancer overexpressed 1 (ORAOV1) gene was constructed via exonuclease III-assisted target recycling and dual enzymes-assisted signal amplification strategy. Capture DNA with sulfhydryl...
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A Novel Hydrophilic Hydrogel with 3D Network Structure for Highly
Efficient Enrichment of N-glycopeptides
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00516F, PaperHaozhou Jin, Wenqing Gao, Rong Liu, Jiaqian Yang, Shun Zhang, Renlu Han, Jing Lin, Sijia Zhang, Jiancheng Yu, Keqi Tang
  Protein glycosylation is of great significance in various physiological processes. Nevertheless, it remains a huge challenge to identify glycopeptides in complex biosamples by direct mass spectrometry analysis due to low...
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The Scaffold of Thermally Activated Delayed Fluorescence Polymer Dots
Towards Aqueous Electrochemiluminescence and Biosensing Application
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00352J, PaperYelin Luo, Bolin Zhao, Baohua Zhang, Yeying Lan, Lijuan Chen, Yuwei Zhang, Yu Bao, Li Niu
  Towards the most efficient, all-exciton-harvesting organic electrochemiluminescence (ECL) for biosensing, aqueous thermally activated delayed fluorescence (TADF)-ECL (aqueous TADF-ECL) was successfully launched to break through the theoretical ECL efficiency limitation of...
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A dual-signal electrochemical immunosensor for detection of HPV16 E6
oncoprotein based on PdBP dendritic ternary nanospheres and MBSi-Chi
nanocomposites
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02120F, PaperTao Wen, Chenchen Xia, Qiubo Yu, Yujie Yu, Siyuan Li, Chunli Zhou, Kexin Sun, Song Yue
  Cervical cancer is a common cancer in women. HPV16 E6 oncoprotein is a reliable biomarker for cervical cancer. Although there are other methods for detecting E6 oncoprotein, the electrochemical method...
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In-situ photoinitiated fabrication of phosphorylcholine functionalized
polyhedral oligomeric silsesquioxane hybrid monolithic column for
mixed-mode capillary electrochromatography
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00195K, PaperXiaoyun Lei, Bingyu Zhang, Yi Zhang, Ting Huang, Fengxiang Tang, Xiaoping Wu
  A monolithic-based mixed-mode stationary phase was prepared for capillary electrochromatography via a fast photoinitiated polymerization of 2-methacryloyloxyethyl phosphorylcholine and polyhedral oligomeric silsesquioxane methacrylate monomer (POSS-MA), in the presence of crosslinker...
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Dual-channel detection of viscosity and pH with near-infrared fluorescent
probes for cancer visualization
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00547F, Paperxiyuan zhang, Fangjun Huo, Yongbin Zhang, yongkang yue, Caixia Yin
  Compared to ordinary cells, tumor cells have its unique microenvironment, such as high viscosity, low pH value, high reactive oxygen species level, overexpression of some proteases, etc. Therefore, viscosity and...
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2D and 3D Maximum-Quantum NMR and diffusion spectroscopy for the
characterization of enzymatic reaction mixtures
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00200K, PaperElena Piersanti, Claudio Righetti, David Ribeaucourt, A. Jalila Simaan, Yasmina Mekmouche, Mickael Lafond, Jean-Guy Berrin, Thierry Tron, Mehdi Yemloul
  1D 1H NMR spectroscopy has been widely used to monitor enzymatic activity by recording the evolution of the spectra of substrates and/or products thanks to the linear response of NMR....
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The protective effect of biomineralized BSA-Mn3O4 nanoparticles on HUVECs
investigating by atomic force microscopy
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00483F, PaperXinyue Guo, weiqi Zhou, Yanxue Guan, Juan Qin, Bailin Zhang, Miaomiao Zhang, Jilin Tang
  Manganese-based nanozymes have been widely used in the field of cell protection due to their various mimic enzyme activities, but the effect of manganese-based nanozymes on the mechanical properties of...
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Aptazymes-induced cascade amplification integrated with volumetric
bar-chart chip for highly sensitive detection of aflatoxin B1 and
adenosine triphosphate
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00650B, PaperYuanyue Han, Xinli Liu, Qiao Zhao, Yanfeng Gao, Dongtao Zhou, Wenxiu Long, Yuzhen Wang, Yujun Song
  A simple aptazymes-induced cascade signal amplification (denoted as ACSA) was integrated with a triple-channel volumetric bar-chart chip (TV-Chip) to visually quantitate aflatoxin B1 (AFB1) and adenosine triphosphate (ATP). Bifunctional aptazymes...
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Raman Spectrum Matching with Contrastive Representation Learning
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00403H, PaperBo Li, Mikkel Schmidt, Tommy Sonne Alstrøm
  Raman spectroscopy is an important, low-cost, non-intrusive technique often used for chemical identification. Typical approaches identify a spectrum by comparing it with a reference database using supervised machine learning, which...
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A triblock probe-polyA-probe electrochemical interfacial engineering for
sensitive analysis of RNAi plant
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00366J, PaperYu Zheng, Lele Wang, Li Xu, Yan Li, Xue Yang, Zhenzhou Yang, Lanying Li, Min Ding, Shuzhen Ren, Feiyan Gong, Jinxue Chang, Chengming Cao, Yanli Wen, Liang Li, Gang Liu
  RNA interference (RNAi) is currently under fast development, which brings improved crop quality and new activity against pests in agriculture, by producing RNAs to specifically inhibit gene expression. This technology,...
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Rational design of a facile camphor-based fluorescence turn-on probe for
real-time tracking of hypochlorous acid in vivo and vitro
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00321J, PaperZhonglong Wang, Yan Zhang, Yueyin Liang, Mingxin Li, Zhiyuan Meng, Shuai Gong, Yiqin Yang, Xu Xu, Shifa Wang
  A simple yet highly effective camphor-derived fluorescent probe named 3-(anthracen-9-ylmethylene)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime (ATHO) was developed based on the oxime recognition receptor and anthracene fluorophore. The probe ATHO displayed a remarkably enhanced...
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Multiple Stem-loop Primers Induced Cascaded Loop-Mediated Isothermal
Amplification for Direct Recognition and Specific Detection of Circular
RNA
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00261B, PaperXin Liu, Pengbo Zhang, Kejian Gao, Xiaoyu Wang, Zhengping Li
  Circular RNAs (circRNAs), as a novel class of endogenous noncoding RNAs, play important roles in many biological functions, such as acting as microRNA sponges and cancer biomarkers. Rapid and sensitive...
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Electrochemiluminescent Sensor Based on Aggregation-induced Emission Probe
for Bioanalytical Detection
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00349J, Tutorial ReviewXiaoyi Lv, Yanping Li, Bo Cui, Yishan Fang, Lishi Wang
  In recent years, with the rapid development of electrochemiluminescence (ECL) sensor, more luminophores have been designed to achieve high-throughput and reliable analysis. Impressively, after the proposed fantastic concept of “aggregation-induced...
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Sensitive detection of fusion transcripts with padlock probe-based
continuous cascade amplification (P-CCA)
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00341D, PaperYutong Chen, Fengxia Su, Yongqiang Cheng, Xiaofei He, Zhengping Li
  Gene fusion, resulted from chromosomal rearrangements, is the juxtaposition of two or more original genes into the same set to form a functional gene. The significant specificity of fusion genes...
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The Application of Physics-Informed Neural Networks to Hydrodynamic
Voltammetry
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00456A, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Haotian Chen, Enno Kätelhön, Richard G Compton
  Electrochemical problems are widely studied in flowing systems since the latter offer improved sensitivity notably for electro-analysis and the possibility of steady-state measurements for fundamental studies even with macro-electrodes. We...
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Single-cell droplet microfluidics for biomedical applications
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02321G, Critical Review Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dan Liu, Meilin Sun, Jinwei Zhang, Rui Hu, Wenzhu Fu, Tingting Xuanyuan, Wenming Liu
  Single-cell manipulation and analysis is critical to the study of many fundamental biological processes and uncovering cellular heterogeneity and presents the potential for extremely valuable applications in biomedical fields, including...
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Profiling of Branched-Chain Fatty Acids via Nitroxide Radical-Directed
Dissociation Integrated on an LC-MS/MS Workflow
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00266C, PaperRuijun Jian, Xue Zhao, Qiaohong Lin, Yu Xia
  Chain modifications on fatty acyls, such as methyl branching, are important to modulate the biochemical and biophysical properties of lipids. The current lipid analysis workflows which mainly rely on collisional-induced...
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An Improved Dual-Channel Capacitively Coupled Contactless Conductivity
Detector with Higher Detection Performance
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00330A, PaperHongyu Nie, Zhihui Li, Xiaokun Wang, Rongmeng Gu, Hongyan Yuan, Yong Guo, Dan Xiao
  Conductivity detector is a widely used electrochemical sensor. It has been the long goal of researchers to achieve higher detection performance. In this contribution, we propose a multi-input capacitively coupled...
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Preparation of a disposable electrochemiluminescence sensor chip based on
MXene-loaded ruthenium luminescent agent and its application in detection
of carcinoembryonic antigen
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00450J, PaperWeiwei Luo, Zhuoxin Ye, Pinyi Ma, Qiong Wu, Daqian Song
  Carcinoembryonic antigen (CEA) is an important cancer marker that plays a significant role in achieving low-cost, rapid and highly sensitive clinical detection. In this work, we developed a disposable electrochemiluminescence...
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Hairpin-functionalized DNA tetrahedral for miRNA imaging in living cells
via self-assembly to form dendrimers
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00080F, PaperWenjing Zhao, Yao Jiang, Huimin Zhou, Shu-Sheng Zhang
  DNA self-assembling nanoprobes with self-transferability and resistance to nuclease degradation have been developed and applied to live cell bio-imaging. In this work, we constructed a hairpin-functionalized DNA tetrahedron (HFDT) intramolecular...
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A sensitive and simple competitive nanozyme-linked apta-sorbent assay for
dual-mode detection of Ochratoxin A
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02335G, PaperMin Li, hao Wang, Xiaodi Yu, Xindi Jia, Chao Zhu, Jiahui Liu, Fan Zhang, Zilei Chen, Mengmeng Yan, Qinzheng Yang
  The enzyme-linked apta-sorbent assay (ELASA) is widely used for detection of small-molecule compounds as a result of low cost and reagent stability of aptamers. However, enzyme labels used in ELASA...
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Magnetic solid-phase extraction of pyrethroid and neonicotinoid
insecticides separately in environmental water samples based on alkaline
or acidic group-functionalized mesoporous silica
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00088A, PaperRui Han, Fei Wang, Chuanfeng Zhao, Meixing Zhang, Shihai Cui, Jing Yang
  Pyrethroids and neonicotinoids are widely used insecticides. However, their residues have unfavorable effects on ecological systems. Magnetic solid phase extraction is a reliable pretreatment method for better detection of insecticide...
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CdSe/ZnS quantum dot-encoded maleic anhydride-grafted PLA microspheres
prepared through membrane emulsification for multiplexed immunoassays of
tumor markers
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00350C, PaperWan-Sheng Tang, Bo Zhang, Laidi Xu, Ning Bao, Qing Zhang, Shou-Nian Ding
  Early diagnosis of tumor markers is of great importance for the successful treatment of cancer. As a high-throughput and high-sensitivity detection technology, liquid suspension biochips based on quantum dots (QDs)...
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A simple fluorescent strategy for labeling liver capillary with carbon
quantum dot-lectin nanoprobe
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D1AN02364K, PaperChang-Zhi An, Chao-Qing Li, Lai-Bo Song, Yanfei He, Wei Chen, Bo Liu, Yuan-Di Zhao
  Taking the hepatic sinusoid (HS) as the main delivery area of liver nutrient and metabolic waste, recognizing its structure is important for the deep understanding of liver function. In this...
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Primer extension activating 3D DNAzyme walker for telomerase activity in
situ imaging and sensitive detection
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00142J, PaperXiaoting Liu, Liyan Zhang, Ling Lu, Wei Jiang, Nan Zhang
  Acquiring information on telomerase activity at multiple levels contributes to better understanding of its role in various physiological and pathological processes. Herein, a primer extension activating 3D DNAzyme walker is...
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Tetrahedral DNA- directed core-satellite assembly as SERS sensor for
mercury ions at the single-particle level
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00402J, PaperNing Feng, Jingjing Shen, Chang Li, Qianqian Zhao, Essy Kouadio Fodjo, Lei Zhang, Shufen Chen, Quli Fan, Lian-Hui Wang
  Facing deteriorating mercury emissions, it is imperative to propose methods for detecting mercury ions (Hg2+) with sensitivity and selection. The SERS spectral-resolved single-particle detection approach can be carried out by...
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Ultrasensitive Detection of Tumor-Derived Small Extracellular Vesicles
Based on Nonlinear Hybridization Chain Reaction Fluorescence Signal
Amplification and Immunomagnetic Separation
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00242F, PaperQianqian Kong, Shasha Cheng, Xinyu Hu, Jia You, Cuiling Zhang, Yuezhong Xian
  Small extracellular vesicles (sEVs) have attracted wide attention as a promising tumor biomarker. However, sensitive and selective detection of sEVs is challenging due to the low levels of sEVs in...
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Detecting Bacterial Infections in Wounds: A Review of Biosensors and
Wearable Sensors in Comparison with Conventional Laboratory Methods
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  Abstract: Analyst, 2022, Accepted Manuscript
  
  DOI : 10.1039/D2AN00157H, Critical ReviewNur Asinah binte Mohamed Salleh, Yuki Tanaka, Laura Sutarlie, Xiaodi Su
  Bacterial infection is a common impediment towards wound healing. Detecting bacterial infections is important to promote wound healing and curb chronic non-healing wounds. In this review, we firstly discuss bacterial...
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